Unc5b (unc-5 netrin receptor B) - Rat Genome Database

Name: Unc5b
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Unc5b (unc-5 netrin receptor B) Rattus norvegicus

Analyze

Symbol:

Unc5b

Name:

unc-5 netrin receptor B

RGD ID:

621756

Description:

Enables netrin receptor activity. Involved in axon guidance and positive regulation of extrinsic apoptotic signaling pathway in absence of ligand. Located in membrane raft. Orthologous to human UNC5B (unc-5 netrin receptor B); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

netrin receptor UNC5B; transmembrane receptor Unc5H2; unc-5 homolog 2; unc-5 homolog B; unc-5 homolog B (C. elegans); Unc5h2

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	UNC5B (unc-5 netrin receptor B)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Unc5b (unc-5 netrin receptor B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Unc5b (unc-5 netrin receptor B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	UNC5B (unc-5 netrin receptor B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	UNC5B (unc-5 netrin receptor B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Unc5b (unc-5 netrin receptor B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	UNC5B (unc-5 netrin receptor B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	UNC5B (unc-5 netrin receptor B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Unc5b (unc-5 netrin receptor B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Unc5b (unc-5 netrin receptor B)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	UNC5B (unc-5 netrin receptor B)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	unc5b (unc-5 netrin receptor B)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	unc-5	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	unc-5	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	unc5b	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	29,240,639 - 29,307,270 (-)	NCBI		GRCr8
mRatBN7.2	20	28,697,726 - 28,764,474 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	28,697,726 - 28,764,537 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	20	29,713,216 - 29,779,955 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	29,099,533 - 29,166,268 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	29,842,007 - 29,908,740 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	30,339,680 - 30,406,593 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	30,339,673 - 30,406,295 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	32,148,315 - 32,215,391 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	28,095,243 - 28,162,204 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	20	28,109,042 - 28,176,004 (-)	NCBI
Celera	20	30,138,282 - 30,201,182 (-)	NCBI		Celera
Cytogenetic Map	20	q11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autism spectrum disorder (ISO)

genetic disease (ISO)

Subarachnoid Hemorrhage (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

(S)-nicotine (ISO)

1,1-dichloroethene (ISO)

1-naphthyl isothiocyanate (EXP)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

5-fluorouracil (ISO)

6-propyl-2-thiouracil (EXP)

8-Br-cAMP (ISO)

acetamide (EXP)

acrylamide (ISO)

aflatoxin B1 (EXP,ISO)

Aflatoxin B2 alpha (ISO)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

amphetamine (EXP)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

benzo[b]fluoranthene (ISO)

benzo[e]pyrene (ISO)

Benzo[k]fluoranthene (ISO)

bis(2-ethylhexyl) phthalate (EXP,ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

butanal (ISO)

Butylparaben (EXP)

cadmium atom (ISO)

cadmium dichloride (ISO)

carbamazepine (ISO)

choline (ISO)

clofibric acid (EXP)

copper(II) sulfate (ISO)

cordycepin (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

DDE (EXP)

decabromodiphenyl ether (EXP)

dexamethasone (ISO)

dibutyl phthalate (EXP)

dichlorine (EXP)

dichloroacetic acid (ISO)

dieldrin (EXP)

disodium selenite (ISO)

dorsomorphin (ISO)

elemental selenium (ISO)

endosulfan (EXP)

entinostat (ISO)

enzacamene (EXP)

epoxiconazole (EXP)

ethanol (ISO)

fenvalerate (EXP)

fipronil (EXP)

folic acid (ISO)

formaldehyde (ISO)

furan (EXP)

hydrogen peroxide (ISO)

hydroquinone (ISO)

indole-3-methanol (EXP)

iron dichloride (ISO)

isotretinoin (ISO)

L-methionine (ISO)

linuron (EXP)

methapyrilene (ISO)

methoxychlor (EXP)

methylmercury chloride (ISO)

Muraglitazar (EXP)

N,N-diethyl-m-toluamide (EXP)

N-methyl-4-phenylpyridinium (ISO)

nicotine (ISO)

nitrofen (EXP)

orphenadrine (EXP)

oxaliplatin (EXP)

ozone (EXP)

paracetamol (EXP,ISO)

pentanal (ISO)

perfluorononanoic acid (ISO)

perfluorooctanoic acid (EXP)

permethrin (EXP)

phenethyl isothiocyanate (ISO)

phenobarbital (ISO)

pirinixic acid (ISO)

prochloraz (EXP)

procymidone (EXP)

propanal (ISO)

rimonabant (ISO)

rotenone (ISO)

SB 431542 (ISO)

selenium atom (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

Tesaglitazar (EXP)

tetrachloromethane (EXP)

thioacetamide (EXP)

titanium dioxide (ISO)

topotecan (EXP)

trichloroethene (ISO)

triclosan (ISO)

Triptolide (ISO)

triptonide (ISO)

troglitazone (EXP,ISO)

trovafloxacin (ISO)

urethane (ISO)

valproic acid (EXP,ISO)

vinclozolin (EXP)

zinc dichloride (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

anterior/posterior axon guidance (IBA,IEA,ISO)

apoptotic process (IEA)

axon guidance (IDA,IGI)

negative regulation of extrinsic apoptotic signaling pathway in absence of ligand (IEA,ISO)

negative regulation of neuron apoptotic process (IEA,ISO)

netrin-activated signaling pathway (IEA)

positive regulation of extrinsic apoptotic signaling pathway in absence of ligand (IMP)

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (IEA,ISO)

Cellular Component

membrane raft (IDA)

plasma membrane (IEA,TAS)

Molecular Function

netrin receptor activity (IBA,IDA,IEA)

protein binding (IPI,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	The dependence receptor UNC5H2/B triggers apoptosis via PP2A-mediated dephosphorylation of DAP kinase.	Guenebeaud C, etal., Mol Cell. 2010 Dec 22;40(6):863-76. doi: 10.1016/j.molcel.2010.11.021.
3.	Vertebrate homologues of C. elegans UNC-5 are candidate netrin receptors.	Leonardo ED, etal., Nature 1997 Apr 24;386(6627):833-8.
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
6.	GOA pipeline	RGD automated data pipeline
7.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
9.	Netrin-1 mediates neuronal survival through PIKE-L interaction with the dependence receptor UNC5B.	Tang X, etal., Nat Cell Biol. 2008 Jun;10(6):698-706. doi: 10.1038/ncb1732. Epub 2008 May 11.
10.	FLRT2 and FLRT3 act as repulsive guidance cues for Unc5-positive neurons.	Yamagishi S, etal., EMBO J. 2011 Jun 14;30(14):2920-33. doi: 10.1038/emboj.2011.189.

Additional References at PubMed

PMID:11387206	PMID:17825258	PMID:18479186	PMID:20628609	PMID:21820492	PMID:26116534	PMID:27856613	PMID:33914819	PMID:35668343

Genomics

Comparative Map Data

Unc5b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	29,240,639 - 29,307,270 (-)	NCBI		GRCr8
mRatBN7.2	20	28,697,726 - 28,764,474 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	28,697,726 - 28,764,537 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	20	29,713,216 - 29,779,955 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	29,099,533 - 29,166,268 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	29,842,007 - 29,908,740 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	30,339,680 - 30,406,593 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	30,339,673 - 30,406,295 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	32,148,315 - 32,215,391 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	28,095,243 - 28,162,204 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	20	28,109,042 - 28,176,004 (-)	NCBI
Celera	20	30,138,282 - 30,201,182 (-)	NCBI		Celera
Cytogenetic Map	20	q11	NCBI

UNC5B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	71,212,570 - 71,302,864 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	71,212,570 - 71,302,864 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	10	72,972,327 - 73,062,621 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	72,642,353 - 72,729,722 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	10	72,642,354 - 72,729,714	NCBI
Celera	10	66,254,788 - 66,343,547 (+)	NCBI		Celera
Cytogenetic Map	10	q22.1	NCBI
HuRef	10	66,966,129 - 67,056,670 (+)	NCBI		HuRef
CHM1_1	10	73,254,992 - 73,345,299 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	10	72,082,200 - 72,172,412 (+)	NCBI		T2T-CHM13v2.0

Unc5b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	60,598,373 - 60,667,360 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	60,598,372 - 60,667,360 (-)	Ensembl		GRCm39 Ensembl
GRCm38	10	60,762,594 - 60,831,581 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	60,762,593 - 60,831,581 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	60,225,343 - 60,294,329 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	60,157,952 - 60,226,938 (-)	NCBI		MGSCv36	mm8
Celera	10	61,863,405 - 61,932,538 (-)	NCBI		Celera
Cytogenetic Map	10	B4	NCBI
cM Map	10	31.52	NCBI

Unc5b
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955437	20,120,946 - 20,199,877 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955437	20,120,996 - 20,199,877 (-)	NCBI	ChiLan1.0	ChiLan1.0

UNC5B
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	83,362,648 - 83,453,001 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	83,367,973 - 83,458,343 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	67,682,415 - 67,772,760 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	10	70,207,998 - 70,298,038 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	70,207,998 - 70,298,038 (+)	Ensembl	panpan1.1		panPan2

UNC5B
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	22,003,131 - 22,084,107 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	4	22,003,131 - 22,081,744 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	4	22,139,026 - 22,219,691 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	4	22,280,582 - 22,358,557 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	4	22,280,284 - 22,357,950 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	4	22,178,248 - 22,258,859 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	22,383,898 - 22,464,744 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	22,736,647 - 22,817,352 (+)	NCBI		UU_Cfam_GSD_1.0

Unc5b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	58,980,118 - 59,055,010 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936521	7,470,663 - 7,547,793 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936521	7,472,788 - 7,547,408 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

UNC5B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	74,120,050 - 74,205,263 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	74,120,055 - 74,208,055 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	80,011,267 - 80,098,887 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

UNC5B
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	59,995,997 - 60,086,663 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666048	20,718,376 - 20,809,131 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Unc5b
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624754	5,204,855 - 5,282,170 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624754	5,204,875 - 5,280,479 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Unc5b
456 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	56
Count of miRNA genes:	51
Interacting mature miRNAs:	56
Transcripts:	ENSRNOT00000038537
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
8694189	Bw153	Body weight QTL 153	3.13	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	20	1	29191651	Rat
9590275	Scort15	Serum corticosterone level QTL 15	3.48	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	20	1	29191651	Rat
7411650	Foco23	Food consumption QTL 23	20.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	1	29191651	Rat
9590109	Sffal8	Serum free fatty acids level QTL 8	5.32	0.01	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	20	1	29191651	Rat
9589155	Insul32	Insulin level QTL 32	6.38	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	20	1	29191651	Rat
6893685	Bw111	Body weight QTL 111	2.7	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	20	1	32578807	Rat
7411668	Foco32	Food consumption QTL 32	8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	1	36600972	Rat
9590252	Scort12	Serum corticosterone level QTL 12	20.46	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	20	1	36600972	Rat
2305926	Iddm37	Insulin dependent diabetes mellitus QTL 37	6		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	20	1527842	46527842	Rat
1641915	Colcr9	Colorectal carcinoma resistance QTL 9	2.97	0.0024	intestine integrity trait (VT:0010554)	benign colorectal tumor number (CMO:0001795)	20	1530655	46530655	Rat
1598816	Memor12	Memory QTL 12	2.4		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	20	2606836	47606836	Rat
4889870	Pur30	Proteinuria QTL 30	19	0.005	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	20	8042410	29322208	Rat
7411652	Foco24	Food consumption QTL 24		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	11757515	54435887	Rat
9590092	Insglur9	Insulin/glucose ratio QTL 9	18.38	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	20	11757515	54435887	Rat
4889610	Pancm3	Pancreatic morphology QTL 3	3.75	0.001	pancreas mass (VT:0010144)	pancreas wet weight (CMO:0000626)	20	17617832	47606836	Rat
2317880	Alcrsp25	Alcohol response QTL 25	2.3		response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	20	17697550	54435887	Rat
2303626	Vencon10	Ventilatory control QTL 10		0.001	respiration trait (VT:0001943)	respiration rate (CMO:0000289)	20	19190721	54435887	Rat
2303578	Gluco50	Glucose level QTL 50	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	20	25106722	54435887	Rat
2303587	Bw93	Body weight QTL 93	13		body mass (VT:0001259)	body weight (CMO:0000012)	20	25106722	54435887	Rat
2300188	Bmd68	Bone mineral density QTL 68	6.4	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	20	25106722	54435887	Rat
1331747	Hrtrt16	Heart rate QTL 16	3.163		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	20	25209734	54435887	Rat

Markers in Region

Unc5h2

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	20	30,349,728 - 30,349,751	NCBI	Rnor6.0
Rnor_5.0	20	32,158,510 - 32,158,533	UniSTS	Rnor5.0
RGSC_v3.4	20	28,105,734 - 28,105,757	UniSTS	RGSC3.4
Celera	20	30,145,090 - 30,145,113	UniSTS
Cytogenetic Map	20	q11	UniSTS

D7S512

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	20	28,727,888 - 28,729,073 (+)	MAPPER	mRatBN7.2
Rnor_6.0	20	30,370,045 - 30,371,229	NCBI	Rnor6.0
Rnor_5.0	20	32,178,827 - 32,180,011	UniSTS	Rnor5.0
RGSC_v3.4	20	28,126,051 - 28,127,235	UniSTS	RGSC3.4
Celera	20	30,164,947 - 30,166,131	UniSTS
Cytogenetic Map	20	q11	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	32	4	4	2	4			53	22	28	11
Low		11	43	27	17	27	8	11	21	13	12		8
Below cutoff			10	10		10					1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_022207	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006256423	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063279489	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063279490	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U87306	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000038537 ⟹ ENSRNOP00000034951

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	20	28,697,726 - 28,717,717 (-)	Ensembl
Rnor_6.0 Ensembl	20	30,339,673 - 30,406,295 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000102258 ⟹ ENSRNOP00000087913

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	20	28,697,726 - 28,764,537 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000109345 ⟹ ENSRNOP00000093505

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	20	28,697,726 - 28,764,537 (-)	Ensembl

RefSeq Acc Id:

NM_022207 ⟹ NP_071543

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	29,240,639 - 29,307,270 (-)	NCBI
mRatBN7.2	20	28,697,726 - 28,764,359 (-)	NCBI
Rnor_6.0	20	30,342,351 - 30,406,197 (-)	NCBI
Rnor_5.0	20	32,148,315 - 32,215,391 (-)	NCBI
RGSC_v3.4	20	28,095,243 - 28,162,204 (-)	RGD
Celera	20	30,138,282 - 30,201,182 (-)	RGD

Sequence:

show sequence

ATGAGGGCCCGGAGCGGGGCGCGGGGCGCGCTGCTGCTGGCGCTGCTGCTCTGCTGGGATCCGA
CACCGAGCTTAGCAGGCATTGACTCTGGTGGCCAGGCACTCCCAGACTCCTTCCCATCAGCACC
CGCGGAGCAGCTGCCTCACTTCCTGCTGGAACCAGAGGATGCCTACATCGTAAAGAACAAGCCA
GTGGAATTGCACTGCCGAGCCTTCCCTGCCACACAGATCTACTTCAAGTGTAATGGCGAGTGGG
TTAGCCAGAAAGGCCACGTCACGCAGGAGAGCCTGGATGAGGCCACAGGCTTGCGAATACGAGA
GGTGCAGATAGAGGTGTCGCGGCAGCAGGTGGAGGAACTTTTTGGGCTCGAGGACTACTGGTGT
CAGTGCGTGGCCTGGAGCTCTTCGGGAACCACCAAGAGTCGCCGAGCCTACATCCGCATTGCCT
ACTTGCGCAAGAACTTTGACCAGGAGCCTCTGGCGAAGGAGGTACCCTTGGATCATGAGGTCCT
TCTGCAGTGCCGCCCACCAGAGGGAGTGCCTGTGGCTGAGGTGGAATGGCTCAAGAATGAAGAT
GTCATCGATCCCGCTCAGGACACTAACTTCCTGCTCACCATTGACCACAACCTCATCATCCGCC
AGGCGCGCCTCTCAGACACAGCCAACTACACCTGTGTGGCAAAGAATATTGTGGCCAAGCGCCG
GAGCACGACGGCCACAGTCATCGTCTATGTGAACGGAGGTTGGTCCAGCTGGGCAGAATGGTCA
CCCTGCTCTAACCGCTGCGGCCGAGGTTGGCAGAAACGTACTAGGACCTGCACCAACCCAGCCC
CACTCAATGGAGGTGCCTTCTGCGAGGGACAGGCTTGCCAGAAGACGGCTTGCACCACCGTGTG
CCCAGTGGATGGAGCGTGGACTGAGTGGAGCAAGTGGTCCGCCTGCAGCACAGAGTGTGCGCAC
TGGCGCAGCCGCGAGTGCATGGCACCGCCGCCCCAGAACGGAGGCCGTGACTGCAGCGGGACGC
TACTTGACTCCAAGAACTGCACCGATGGGCTGTGCGTGCTGAATCAGAGAACTCTAAACGACCC
TAAAAGCCGCCCCCTGGAGCCGTCGGGAGACGTGGCGCTGTATGCGGGCCTCGTGGTGGCCGTC
TTTGTGGTTCTGGCAGTTCTCATGGCTGTAGGAGTGATCGTGTACCGGAGAAACTGCCGGGACT
TCGACACGGACATCACTGACTCCTCTGCTGCCCTCACTGGTGGTTTCCACCCCGTCAACTTCAA
GACTGCAAGGCCCAGCAACCCACAGCTCCTGCACCCATCCGCCCCTCCGGACCTAACGGCCAGT
GCTGGCATCTACCGCGGACCTGTGTATGCCCTGCAGGACTCTGCCGACAAGATCCCTATGACTA
ATTCACCCCTTCTGGATCCCTTGCCCAGCCTCAAGATCAAGGTCTATGACTCCAGCACCATCGG
CTCTGGGGCTGGCCTGGCTGATGGAGCCGACCTGCTGGGTGTCTTACCACCCGGTACATACCCA
GGCGATTTCTCCCGGGACACCCACTTCCTGCACCTGCGCAGCGCCAGCCTTGGTTCCCAGCACC
TCCTGGGCCTCCCTCGAGACCCCAGCAGCAGTGTCAGTGGCACCTTTGGTTGCCTGGGTGGGAG
GCTGACCATTCCCGGCACAGGGGTCAGCCTGTTGGTACCAAATGGAGCCATTCCCCAGGGCAAG
TTCTATGACTTGTATCTACGTATCAACAAGACTGAAAGCACCCTCCCACTTTCGGAAGGTTCCC
AGACAGTATTGAGCCCCTCGGTGACCTGCGGGCCCACGGGCCTCCTCCTGTGCCGCCCTGTTGT
CCTCACTGTGCCCCACTGTGCTGAAGTCATTGCCGGAGACTGGATCTTCCAGCTCAAGACCCAG
GCCCATCAGGGCCACTGGGAGGAGGTGGTGACTTTGGATGAGGAGACTCTGAACACCCCCTGCT
ACTGCCAGCTAGAGGCTAAATCCTGCCACATCCTGTTGGACCAGCTGGGTACCTACGTGTTCAC
GGGCGAGTCCTACTCCCGCTCCGCAGTCAAGCGGCTCCAGCTAGCCATCTTCGCCCCAGCCCTC
TGCACCTCCCTGGAGTATAGTCTCAGGGTCTACTGTCTGGAGGACACTCCTGCAGCACTGAAGG
AGGTCCTAGAGCTGGAGAGGACTCTGGGTGGCTACTTGGTGGAGGAGCCCAAGACTTTGCTCTT
TAAGGACAGTTACCACAACCTACGNCTCTCCCTCCATGACATCCCCCATGCCCACTGGAGGAGC
AAACTACTGGCCAAGTACCAGGAGATTCCCTTCTACCATGTGTGGAACGGCAGCCAGAAAGCCC
TGCACTGCACTTTCACCCTGGAGAGACATAGCCTAGCCTCCACTGAGTTCACCTGTAAGGTCTG
CGTGCGGCAGGTAGAAGGGGAAGGCCAGATTTTCCAGCTGCACACCACGCTGGCTGAGACGCCT
GCTGGCTCCCTGGATGCACTCTGCTCTGCCCCTGGCAATGCTGCCACCACACAGCTGGGACCCT
ATGCCTTCAAGATACCACTGTCCATCCGCCAGAAGATCTGCAACAGCCTGGACGCCCCCAACTC
ACGGGGCAATGACTGGCGGCTGTTGGCACAGAAGCTCTCCATGGACCGGTACCTGAACTACTTC
GCCACCAAAGCTAGTCCCACAGGCGTGATCTTAGACCTCTGGGAAGCTCGGCAGCAGGATGATG
GGGACCTCAACAGCCTGGCCAGTGCCTTGGAGGAGATGGGCAAGAGTGAGATGCTGGTAGCCAT
GACCACTGATGGCGATTGCTGA

hide sequence

RefSeq Acc Id:

XM_006256423 ⟹ XP_006256485

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	29,240,639 - 29,307,007 (-)	NCBI
mRatBN7.2	20	28,697,726 - 28,764,474 (-)	NCBI
Rnor_6.0	20	30,339,680 - 30,406,593 (-)	NCBI
Rnor_5.0	20	32,148,315 - 32,215,391 (-)	NCBI

Sequence:

show sequence

CGGGCGAAGGTGCCGAGCCGCGGGGAGCGGCAGGGCGCGGAGGGGAGCGCACACCCCACTTGGA
CAGACTTTGCGGCGCGGCCGCTGCGAGCGCCACTGAGCGCACTCCACTGGGATCGCGCAACTTC
GGAGCAGGGCGCGGACGGCGGTCGCCGCCGGAGAGCGCGGAAAGGGCGCACCAGAGCCGGGTTC
CCCAGCGGCGTCCACTCCCGGAGCGCTCCGAGCCTCCGGGCAGTCTCCCGGCGCTGCGTGGTTG
CCGCTGCGCCCACGGAGGGCACGGGCTGGCGCTGCCGGGCGCCTGCGAGGACGGCGAGGCGGCG
GCGAAGGCGAAGGCGGCGAGGCTGGGGACCGGGAAAGAACCCCGAGGGAGAGGCGCCCGGGCCG
GGCGACAGGAGCATGAGGGCCCGGAGCGGGGCGCGGGGCGCGCTGCTGCTGCTGGCGCTGCTGC
TCTGCTGGGATCCGACACCGAGCTTAGCAGGCATTGACTCTGGTGGCCAGGCACTCCCAGACTC
CTTCCCATCAGCACCCGCGGAGCAGCTGCCTCACTTCCTGCTGGAACCAGAGGATGCCTACATC
GTAAAGAACAAGCCAGTGGAATTGCACTGCCGAGCCTTCCCTGCCACACAGATCTACTTCAAGT
GTAATGGCGAGTGGGTTAGCCAGAAAGGCCACGTCACGCAGGAGAGCCTGGATGAGGCCACAGG
CTTGCGAATACGAGAGGTGCAGATAGAGGTGTCGCGGCAGCAGGTGGAGGAACTCTTTGGGCTC
GAGGACTACTGGTGTCAGTGCGTGGCCTGGAGCTCTTCGGGAACCACCAAGAGTCGCCGAGCCT
ACATCCGCATTGCCTACTTGCGCAAGAACTTTGACCAGGAGCCTCTGGCGAAGGAGGTACCCTT
GGATCATGAGGTCCTTCTGCAGTGCCGCCCACCAGAGGGAGTGCCTGTGGCTGAGGTGGAATGG
CTCAAGAATGAAGATGTCATCGATCCCGCTCAGGACACTAACTTCCTGCTCACCATTGACCACA
ACCTCATCATCCGCCAGGCGCGCCTCTCAGACACAGCCAACTACACCTGTGTGGCCAAGAATAT
TGTGGCCAAGCGCCGGAGCACGACGGCCACAGTCATCGTCTATGTGAACGGAGGTTGGTCCAGC
TGGGCAGAATGGTCACCCTGCTCTAACCGCTGCGGCCGAGGTTGGCAGAAACGTACTAGGACCT
GCACCAACCCAGCCCCACTCAATGGAGGTGCCTTCTGCGAGGGACAGGCTTTCCAGAAGACGGC
TTGCACCACCGTGTGCCCAGTGGATGGAGCGTGGACTGAGTGGAGCAAGTGGTCCGCCTGCAGC
ACAGAGTGTGCGCACTGGCGCAGCCGCGAGTGCATGGCACCGCCGCCCCAGAACGGAGGCCGCG
ACTGCAGCGGGACGCTACTTGACTCCAAGAACTGCACCGATGGGCTGTGCGTGCTGACCCTGGA
GCCGTCGGGAGACGTGGCGCTGTATGCGGGCCTCGTGGTGGCCGTCTTTGTGGTTCTGGCAGTT
CTCATGGCTGTAGGAGTGATCGTGTACCGGAGAAACTGCCGGGACTTCGACACGGACATCACTG
ACTCCTCTGCTGCCCTCACTGGTGGTTTCCACCCCGTCAACTTCAAGACTGCAAGGCCCAGCAA
CCCACAGCTCCTGCACCCATCCGCCCCTCCGGACCTAACGGCCAGTGCTGGCATCTACCGCGGA
CCTGTGTATGCCCTGCAGGACTCCGCCGACAAGATCCCTATGACTAATTCACCCCTGCTGGATC
CCTTGCCCAGCCTCAAGATCAAGGTCTATGACTCCAGCACCATCGGCTCTGGGGCTGGCCTGGC
TGATGGAGCCGACCTGCTGGGTGTCTTACCACCCGGTACATACCCAGGCGATTTCTCCCGGGAC
ACCCACTTCCTGCACCTGCGCAGCGCCAGCCTCGGTTCCCAGCACCTCCTGGGCCTCCCTCGAG
ACCCCAGCAGCAGTGTCAGTGGCACCTTTGGTTGCCTGGGTGGGAGGCTGACCATTCCCGGCAC
AGGGGTCAGCCTGTTGGTACCAAATGGAGCCATTCCCCAGGGCAAGTTCTATGACTTGTATCTA
CGTATCAACAAGACTGAAAGCACCCTCCCACTTTCAGAAGGTTCCCAGACAGTATTGAGCCCCT
CGGTGACCTGCGGGCCCACGGGCCTCCTCCTGTGCCGCCCTGTTGTCCTCACTGTGCCCCACTG
TGCTGAAGTCATTGCCGGAGACTGGATCTTCCAGCTCAAGACCCAGGCCCATCAGGGCCACTGG
GAGGAGGTGGTGACTTTGGATGAGGAGACTCTGAACACCCCCTGCTACTGCCAGCTAGAGGCTA
AATCCTGCCACATCCTGTTGGACCAGCTGGGTACCTACGTGTTCACGGGCGAGTCCTACTCCCG
CTCCGCAGTCAAGCGGCTCCAGCTAGCCATCTTCGCCCCAGCCCTCTGCACCTCCCTGGAGTAT
AGTCTCAGGGTCTACTGTCTGGAGGACACTCCTGCAGCACTGAAGGAGGTCCTAGAACTGGAGA
GGACTCTGGGTGGCTACTTGGTGGAGGAGCCCAAGCCTTTGCTCTTTAAGGACAGTTACCACAA
CCTACGCCTCTCCCTCCATGACATCCCCCATGCCCACTGGAGGAGCAAACTACTGGCCAAGTAC
CAGGAGATTCCCTTCTACCATGTGTGGAACGGCAGCCAGAAAGCCCTGCACTGCACTTTCACCC
TGGAGAGACATAGCCTAGCCTCCACTGAGTTCACCTGTAAGGTCTGCGTGCGGCAGGTAGAAGG
GGAAGGCCAGATTTTCCAGCTGCACACCACGCTGGCTGAGACGCCTGCTGGCTCCCTGGATGCA
CTCTGCTCTGCCCCTGGCAATGCTGCCACCACACAGCTGGGACCCTATGCCTTCAAGATACCAC
TGTCCATCCGCCAGAAGATCTGCAACAGCCTGGACGCCCCCAACTCACGGGGCAATGACTGGCG
GCTGTTGGCACAGAAGCTCTCCATGGACCGGTACCTGAACTACTTCGCCACCAAAGCTAGTCCC
ACAGGCGTGATCTTAGACCTCTGGGAAGCTCGGCAGCAGGATGATGGGGACCTCAACAGCCTGG
CCAGTGCCTTGGAGGAGATGGGCAAGAGTGAGATGCTGGTAGCCATGACCACTGATGGCGATTG
CTGAGTGCCTGTGACCTCAGGCCTGTGGGGGCCAGTAGGAGATGGTGCAAGGAGGCCTGGCAAC
CTCTCTGTGGGGGTGTCCAACCTCCACCATCCCTGGCTCACAGCTGGAATGGTCCCTCACGCCC
CTCCCCACCACAACCCTCAGACCACCACCAGCCTTAGAAAGACTCTGTGCTCTACTGCCAGGAG
GCGGGGATCCTCGGCCTCACCGTTTCCCCAGCTCACTCTGGGGTGGGCTGAGTCCTCGGGGGCA
GCTGAAGGCCAGAGGCTTTCCCCCCACAACACACCACCCTCAGCCCTGTGACTTTGGAGGCCCA
CGGGTTTCAGTTCTGTGTTCACATGGTCCTCGGCTAAGGACTGCTCTCCTATCCCGGGTCCTCT
CTGAAAGGTCAAGTTCAGTTCAAGCAAACTGCTCGCTTTCTCCTGCCCACAAACTTAGAGAGAG
AGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAATATGAGCCTCAGAA
GTCAGCGAGACTCGGGCAATGATAGTGCAAAAACTATAAGGGCAAAGAAACCCAGTTTCTTAGG
GAACGAAAATGATTTATCATCCAGATACCTGGATAGGTCCTTTTTAAGAAAACAAACAAACAAA
CAAAAAAGTAAGGAAAGAAAAAAAAACTTTTATCCTTGAATGTGGTTAAGAGTGGCTGTGCTTG
TGGTTTGGGCCATAGGCAAGTGCATTCTCGGGCACACGTGTGCATGGGTGTGGTCAGCAAGAGA
CTGCACAGGGGAATACTTTGCTGTGGCAAGACCTCAGTGTCCCTAGCTGTGCAGGGAGCTGAGA
CAGGGTTTTAGCCATGACACCAAGTGCTAAACTCTTGAGCAGAGGCTGGCCTGGTGGTCCTCCC
ACTCTCTGTGCTCTTCTGTGGCCTCCTCTAGTTTTGGGGAACCCAAATGGAGGCCCAGGCCAGC
TGTGATGGGGGAGACTGTTCAGGTCTGTTTTACTTTGGTGATTCCTGGTCTAGTGATGGCCAAG
GGTGTGGCTCTTACTGAGAGGGAGGGGCTATTCCAGGGATGGTTCCCTCCCAGGTTGGATGGCT
TTGTGTCTAGGCTGGTACTAGCCAGTCCGCACCCTGTTTACCCACTCATCTTCCTTCTTGGAGT
CAGGAGCTGTGAAGGTAACTTTTCCACCCACCTTTGGCCACAGCCCATTCTGGGATGTTCCACA
GGGCCACAGTAGAAGGGATGAATTCTTGTCCCTTCAGCCCACGGGCAGTGATGGAGACCAGGAC
CTCACTGTAGACATAGAGATCCTATCGAAGGATACTTACTGTAGAATCAAGACTTGCTGTAAAA
CTTCCCTGAACTCCCATTGAGACCACCCTGGCAGGTCCTGAGCTTTGAAAGTTGGGGCCTCTGT
GGGGAGGCAGGTTTCATGGCCACAGACCCAGCGAGCGTCTGTGCCCTGGGTTTCCGCAGTGGCT
CCTGAAGTGGGACTCTAAGACTGAGACCGAGGTGCTCCTGGCATCTAGGTGAATGGTGCCTCAT
AGAGTGTCCTCAGCTCCTCCTGCCAAAGATGCTCATCCCCGTGGGCATACTCTTGCTGGTCACT
GTTAGCCCGCACATAGAAATGGGAAGCCCGGGAACCAAGTTGTAGCTATGCTGTGTGACTTCAG
GCACATAACCGCTTTCTCTGGGCTTAAGTGTCCTTTTATCCTGGGATGCTCCACGAGGCCCCTT
AGGTTCCCACACTCCTCTGGGACTCTAGTAGAGACAAGTTGATTGTGGTCTGCATTTGCCCATC
CTCAGAAACCTGCCTGTCTGGGCCCTGGTGGGAGCACGTAGGGAGCGAGTCCCAGTTTACGGTC
TGACTCTTGGGAGGTGCTCAGCATCTGGAGCACAAAGGCTGGAGCTGGAGCCTGGGGCAGGGCT
CCAACCTCATAGTTTGGTAGCAGCCGCCCGGGGAATGTCGGCCAACTCTGGGCAGAGCCAGGCA
GGGCTATTGGGTTGGGTTTCCACTCCTGCCTCCAATGAGATGGCACCTCCCCTTCCCATTCCTG
GCCAGCTTGGTGTTGCCGGGTCCTGCAGGGTATTTCTGTGTCATCGTGTGTGTGTGTGTGTGTG
TGTGTGTGTGTGTGTGTGTGTGTGTGCGCGCGCACGCGCGCGCGTGCGTGCTTGCCTGTGTTTT
TCAACTTGGGCACATCAGGGCACCCCTCCTAGAACGCACACACTTGTCCCCACACGTGGACATG
ACCTCTGTGCCCAGGCTCGTGCCACTGAGGAGGACATGCCTGTTTGCTGTCCCAAGTCAGTCAG
TCCGTGTATCTCCTAATGTGCCTCTCCTGCCCTTCCTCAGGGGGCTCCAGGCTTCTGCGCTCTG
GCTAGACACCTCCTGAGGGACAGAGACCCTCCTCATCCCTGGATCTGCCAGGGCTCTCTGGTCC
CCATCTTGAGGCTCCCAGGCATCTGAGTCAGCACCTTCCTCCCGCCCTCAGAGGTCGGGTGTGT
GGGAGCTTGGATGTCAGGCTGTGAACATGGCTGTGTGTCTGTGGGTTCTGATCCACTGGGGATA
GTCCCAGCCCCACCCGTTCATTCTGTAAACAACTTGTAAATAACCTTTAGCATTCCTCTTGTAA
CAAAATTAATTTTTATGAAATAAATTATATTTCCTAGTCTATAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_063279489 ⟹ XP_063135559

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	29,240,639 - 29,284,915 (-)	NCBI

RefSeq Acc Id:

XM_063279490 ⟹ XP_063135560

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	29,240,639 - 29,284,917 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_071543	(Get FASTA)	NCBI Sequence Viewer
	XP_006256485	(Get FASTA)	NCBI Sequence Viewer
	XP_063135559	(Get FASTA)	NCBI Sequence Viewer
	XP_063135560	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAB57679	(Get FASTA)	NCBI Sequence Viewer
	EDL93040	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000034951.5
	ENSRNOP00000087913
	ENSRNOP00000087913.1
	ENSRNOP00000093505
	ENSRNOP00000093505.1
GenBank Protein	O08722	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_071543 ⟸ NM_022207
- Peptide Label:	precursor
- UniProtKB:	O08722 (UniProtKB/Swiss-Prot), A0A8I6AKI5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MRARSGARGALLLALLLCWDPTPSLAGIDSGGQALPDSFPSAPAEQLPHFLLEPEDAYIVKNKP VELHCRAFPATQIYFKCNGEWVSQKGHVTQESLDEATGLRIREVQIEVSRQQVEELFGLEDYWC QCVAWSSSGTTKSRRAYIRIAYLRKNFDQEPLAKEVPLDHEVLLQCRPPEGVPVAEVEWLKNED VIDPAQDTNFLLTIDHNLIIRQARLSDTANYTCVAKNIVAKRRSTTATVIVYVNGGWSSWAEWS PCSNRCGRGWQKRTRTCTNPAPLNGGAFCEGQACQKTACTTVCPVDGAWTEWSKWSACSTECAH WRSRECMAPPPQNGGRDCSGTLLDSKNCTDGLCVLNQRTLNDPKSRPLEPSGDVALYAGLVVAV FVVLAVLMAVGVIVYRRNCRDFDTDITDSSAALTGGFHPVNFKTARPSNPQLLHPSAPPDLTAS AGIYRGPVYALQDSADKIPMTNSPLLDPLPSLKIKVYDSSTIGSGAGLADGADLLGVLPPGTYP GDFSRDTHFLHLRSASLGSQHLLGLPRDPSSSVSGTFGCLGGRLTIPGTGVSLLVPNGAIPQGK FYDLYLRINKTESTLPLSEGSQTVLSPSVTCGPTGLLLCRPVVLTVPHCAEVIAGDWIFQLKTQ AHQGHWEEVVTLDEETLNTPCYCQLEAKSCHILLDQLGTYVFTGESYSRSAVKRLQLAIFAPAL CTSLEYSLRVYCLEDTPAALKEVLELERTLGGYLVEEPKTLLFKDSYHNLRLSLHDIPHAHWRS KLLAKYQEIPFYHVWNGSQKALHCTFTLERHSLASTEFTCKVCVRQVEGEGQIFQLHTTLAETP AGSLDALCSAPGNAATTQLGPYAFKIPLSIRQKICNSLDAPNSRGNDWRLLAQKLSMDRYLNYF ATKASPTGVILDLWEARQQDDGDLNSLASALEEMGKSEMLVAMTTDGDC hide sequence

RefSeq Acc Id:	XP_006256485 ⟸ XM_006256423
- Peptide Label:	isoform X3
- UniProtKB:	O08722 (UniProtKB/Swiss-Prot), A0A8I6A411 (UniProtKB/TrEMBL)
- Sequence:	show sequence MRARSGARGALLLLALLLCWDPTPSLAGIDSGGQALPDSFPSAPAEQLPHFLLEPEDAYIVKNK PVELHCRAFPATQIYFKCNGEWVSQKGHVTQESLDEATGLRIREVQIEVSRQQVEELFGLEDYW CQCVAWSSSGTTKSRRAYIRIAYLRKNFDQEPLAKEVPLDHEVLLQCRPPEGVPVAEVEWLKNE DVIDPAQDTNFLLTIDHNLIIRQARLSDTANYTCVAKNIVAKRRSTTATVIVYVNGGWSSWAEW SPCSNRCGRGWQKRTRTCTNPAPLNGGAFCEGQAFQKTACTTVCPVDGAWTEWSKWSACSTECA HWRSRECMAPPPQNGGRDCSGTLLDSKNCTDGLCVLTLEPSGDVALYAGLVVAVFVVLAVLMAV GVIVYRRNCRDFDTDITDSSAALTGGFHPVNFKTARPSNPQLLHPSAPPDLTASAGIYRGPVYA LQDSADKIPMTNSPLLDPLPSLKIKVYDSSTIGSGAGLADGADLLGVLPPGTYPGDFSRDTHFL HLRSASLGSQHLLGLPRDPSSSVSGTFGCLGGRLTIPGTGVSLLVPNGAIPQGKFYDLYLRINK TESTLPLSEGSQTVLSPSVTCGPTGLLLCRPVVLTVPHCAEVIAGDWIFQLKTQAHQGHWEEVV TLDEETLNTPCYCQLEAKSCHILLDQLGTYVFTGESYSRSAVKRLQLAIFAPALCTSLEYSLRV YCLEDTPAALKEVLELERTLGGYLVEEPKPLLFKDSYHNLRLSLHDIPHAHWRSKLLAKYQEIP FYHVWNGSQKALHCTFTLERHSLASTEFTCKVCVRQVEGEGQIFQLHTTLAETPAGSLDALCSA PGNAATTQLGPYAFKIPLSIRQKICNSLDAPNSRGNDWRLLAQKLSMDRYLNYFATKASPTGVI LDLWEARQQDDGDLNSLASALEEMGKSEMLVAMTTDGDC hide sequence

RefSeq Acc Id:

ENSRNOP00000034951 ⟸ ENSRNOT00000038537

RefSeq Acc Id:

ENSRNOP00000087913 ⟸ ENSRNOT00000102258

RefSeq Acc Id:

ENSRNOP00000093505 ⟸ ENSRNOT00000109345

RefSeq Acc Id:	XP_063135560 ⟸ XM_063279490
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_063135559 ⟸ XM_063279489
- Peptide Label:	isoform X1

Protein Domains

Death Ig-like Ig-like C2-type TSP type-1 ZU5

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-O08722-F1-model_v2	AlphaFold	O08722	1-945	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:621756	AgrOrtholog
BioCyc Gene	G2FUF-3738	BioCyc
Ensembl Genes	ENSRNOG00000000567	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000038537.6	UniProtKB/TrEMBL
	ENSRNOT00000102258.1	UniProtKB/TrEMBL
	ENSRNOT00000109345	ENTREZGENE
	ENSRNOT00000109345.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.533.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	2.20.100.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	2.60.220.30	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	2.60.40.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	DEATH-like_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Death_domain	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Death_UNC5B	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig-like_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig-like_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig_I-set	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig_sub	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig_sub2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TSP1_rpt	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TSP1_rpt_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	UNC5	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	UPA	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ZU5_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:60630	UniProtKB/Swiss-Prot
NCBI Gene	60630	ENTREZGENE
PANTHER	NETRIN RECEPTOR UNC5B	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PROPERDIN	UniProtKB/TrEMBL
	PROPERDIN	UniProtKB/TrEMBL
	PTHR12582	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Death	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	I-set	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TSP_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	UPA	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ZU5	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Unc5b	PhenoGen
PRINTS	TSP1REPEAT	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	DEATH_DOMAIN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	IG_LIKE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TSP1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ZU5	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000000567	RatGTEx
SMART	DEATH	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	IGc2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SM00409	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TSP1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ZU5	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF47986	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF48726	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF82895	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8I6A411	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AKI5	ENTREZGENE, UniProtKB/TrEMBL
	A6K3Y2_RAT	UniProtKB/TrEMBL
	F1LNE2_RAT	UniProtKB/TrEMBL
	O08722	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-06-26	Unc5b	unc-5 netrin receptor B	Unc5b	unc-5 homolog B (C. elegans)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-09-10	Unc5b	unc-5 homolog B (C. elegans)	Unc5h2	transmembrane receptor Unc5H2	Symbol and Name updated	1299863	APPROVED
2002-08-07	Unc5h2	transmembrane receptor Unc5H2			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD