Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Avpi1 | Rat | 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene | multiple interactions | ISO | Avpi1 (Mus musculus) | 6480464 | [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... | CTD | PMID:25510870 | Avpi1 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Avpi1 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of AVPI1 mRNA | CTD | PMID:22206623 | Avpi1 | Rat | 17alpha-ethynylestradiol | affects expression | ISO | Avpi1 (Mus musculus) | 6480464 | Ethinyl Estradiol affects the expression of AVPI1 mRNA | CTD | PMID:17555576 | Avpi1 | Rat | 17alpha-ethynylestradiol | multiple interactions | ISO | Avpi1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of AVPI1 mRNA | CTD | PMID:17942748 | Avpi1 | Rat | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of AVPI1 mRNA | CTD | PMID:17557909 | Avpi1 | Rat | 17alpha-ethynylestradiol | increases expression | ISO | Avpi1 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of AVPI1 mRNA | CTD | PMID:17942748 | Avpi1 | Rat | 17beta-estradiol | multiple interactions | ISO | AVPI1 (Homo sapiens) | 6480464 | [Estradiol co-treated with Progesterone] results in increased expression of AVPI1 mRNA; [Estradiol co-treated with TGFB1 more ... | CTD | PMID:20660070|PMID:30165855 | Avpi1 | Rat | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | ISO | Avpi1 (Mus musculus) | 6480464 | [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... | CTD | PMID:25510870 | Avpi1 | Rat | 2,2',5,5'-tetrachlorobiphenyl | multiple interactions | ISO | Avpi1 (Mus musculus) | 6480464 | [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... | CTD | PMID:25510870 | Avpi1 | Rat | 2,2',5,5'-tetrachlorobiphenyl | increases expression | ISO | AVPI1 (Homo sapiens) | 6480464 | 2,5,2',5'-tetrachlorobiphenyl results in increased expression of AVPI1 mRNA | CTD | PMID:36804509 | Avpi1 | Rat | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | ISO | Avpi1 (Mus musculus) | 6480464 | 2,3',4,4',5-pentachlorobiphenyl results in increased expression of AVPI1 mRNA | CTD | PMID:31388691 | Avpi1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Avpi1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of AVPI1 mRNA | CTD | PMID:17942748 | Avpi1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of AVPI1 mRNA | CTD | PMID:34747641 | Avpi1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Avpi1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of AVPI1 mRNA | CTD | PMID:21570461 | Avpi1 | Rat | 2,4,4'-trichlorobiphenyl | multiple interactions | ISO | Avpi1 (Mus musculus) | 6480464 | [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... | CTD | PMID:25510870 | Avpi1 | Rat | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | affects expression | ISO | Avpi1 (Mus musculus) | 6480464 | 2,2',4,4',5-brominated diphenyl ether affects the expression of AVPI1 mRNA | CTD | PMID:38648751 | Avpi1 | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2,4-dinitrotoluene affects the expression of AVPI1 mRNA | CTD | PMID:21346803 | Avpi1 | Rat | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2,6-dinitrotoluene affects the expression of AVPI1 mRNA | CTD | PMID:21346803 | Avpi1 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | Avpi1 (Mus musculus) | 6480464 | bisphenol S results in increased expression of AVPI1 mRNA | CTD | PMID:39298647 | Avpi1 | Rat | 8-Br-cAMP | increases expression | ISO | AVPI1 (Homo sapiens) | 6480464 | 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of AVPI1 mRNA | CTD | PMID:22079614 | Avpi1 | Rat | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of AVPI1 mRNA | CTD | PMID:33354967 | Avpi1 | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of AVPI1 mRNA | CTD | PMID:16483693 | Avpi1 | Rat | amphetamine | increases expression | EXP | | 6480464 | Amphetamine results in increased expression of AVPI1 mRNA | CTD | PMID:30779732 | Avpi1 | Rat | aristolochic acid A | increases expression | ISO | AVPI1 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of AVPI1 mRNA | CTD | PMID:33212167 | Avpi1 | Rat | atrazine | increases expression | ISO | AVPI1 (Homo sapiens) | 6480464 | Atrazine results in increased expression of AVPI1 mRNA | CTD | PMID:18461179 | Avpi1 | Rat | benzene | increases expression | ISO | AVPI1 (Homo sapiens) | 6480464 | Benzene results in increased expression of AVPI1 mRNA | CTD | PMID:19162166 | Avpi1 | Rat | benzo[a]pyrene | increases expression | ISO | Avpi1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of AVPI1 mRNA | CTD | PMID:19770486 | Avpi1 | Rat | benzo[a]pyrene | increases methylation | ISO | AVPI1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of AVPI1 promoter | CTD | PMID:27901495 | Avpi1 | Rat | benzo[b]fluoranthene | increases expression | ISO | Avpi1 (Mus musculus) | 6480464 | benzo(b)fluoranthene results in increased expression of AVPI1 mRNA | CTD | PMID:26377693 | Avpi1 | Rat | beta-lapachone | increases expression | ISO | AVPI1 (Homo sapiens) | 6480464 | beta-lapachone results in increased expression of AVPI1 mRNA | CTD | PMID:38218311 | Avpi1 | Rat | bisphenol A | increases expression | ISO | AVPI1 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of AVPI1 mRNA | CTD | PMID:25047013 | Avpi1 | Rat | bisphenol A | increases expression | ISO | Avpi1 (Mus musculus) | 6480464 | bisphenol A results in increased expression of AVPI1 mRNA | CTD | PMID:32156529|PMID:38074096 | Avpi1 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of AVPI1 mRNA | CTD | PMID:32145629 | Avpi1 | Rat | bisphenol A | affects expression | ISO | AVPI1 (Homo sapiens) | 6480464 | bisphenol A affects the expression of AVPI1 mRNA | CTD | PMID:30903817 | Avpi1 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of AVPI1 mRNA | CTD | PMID:25181051 | Avpi1 | Rat | butanal | increases expression | ISO | AVPI1 (Homo sapiens) | 6480464 | butyraldehyde results in increased expression of AVPI1 mRNA | CTD | PMID:26079696 | Avpi1 | Rat | cadmium atom | increases expression | ISO | AVPI1 (Homo sapiens) | 6480464 | Cadmium results in increased expression of AVPI1 mRNA | CTD | PMID:21120746 | Avpi1 | Rat | cadmium dichloride | decreases expression | ISO | AVPI1 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of AVPI1 mRNA | CTD | PMID:38568856 | Avpi1 | Rat | chloropicrin | affects expression | ISO | AVPI1 (Homo sapiens) | 6480464 | chloropicrin affects the expression of AVPI1 mRNA | CTD | PMID:26352163 | Avpi1 | Rat | choline | multiple interactions | ISO | Avpi1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression more ... | CTD | PMID:20938992 | Avpi1 | Rat | chromium(6+) | affects expression | ISO | Avpi1 (Mus musculus) | 6480464 | chromium hexavalent ion affects the expression of AVPI1 mRNA | CTD | PMID:28472532 | Avpi1 | Rat | cisplatin | multiple interactions | ISO | AVPI1 (Homo sapiens) | 6480464 | Cisplatin promotes the reaction [Piroxicam results in decreased expression of AVPI1 mRNA] | CTD | PMID:21858171 | Avpi1 | Rat | cisplatin | increases expression | ISO | AVPI1 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of AVPI1 mRNA | CTD | PMID:19561079|PMID:27594783 | Avpi1 | Rat | cobalt dichloride | increases expression | ISO | AVPI1 (Homo sapiens) | 6480464 | cobaltous chloride results in increased expression of AVPI1 mRNA | CTD | PMID:19376846 | Avpi1 | Rat | copper atom | decreases expression | EXP | | 6480464 | Copper results in decreased expression of AVPI1 mRNA | CTD | PMID:30556269 | Avpi1 | Rat | copper(0) | decreases expression | EXP | | 6480464 | Copper results in decreased expression of AVPI1 mRNA | CTD | PMID:30556269 | Avpi1 | Rat | copper(II) sulfate | decreases expression | ISO | AVPI1 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of AVPI1 mRNA | CTD | PMID:19549813 | Avpi1 | Rat | cyclosporin A | decreases expression | ISO | AVPI1 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of AVPI1 mRNA | CTD | PMID:20106945|PMID:25562108 | Avpi1 | Rat | Dibutyl phosphate | affects expression | ISO | AVPI1 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of AVPI1 mRNA | CTD | PMID:37042841 | Avpi1 | Rat | dioxygen | multiple interactions | ISO | Avpi1 (Mus musculus) | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of AVPI1 mRNA | CTD | PMID:30529165 | Avpi1 | Rat | endosulfan | increases expression | EXP | | 6480464 | Endosulfan results in increased expression of AVPI1 mRNA | CTD | PMID:29391264 | Avpi1 | Rat | ethanol | increases expression | ISO | Avpi1 (Mus musculus) | 6480464 | Ethanol results in increased expression of AVPI1 mRNA | CTD | PMID:30319688 | Avpi1 | Rat | ethyl methanesulfonate | increases expression | ISO | AVPI1 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of AVPI1 mRNA | CTD | PMID:23649840 | Avpi1 | Rat | etoposide | affects response to substance | ISO | AVPI1 (Homo sapiens) | 6480464 | AVPI1 protein affects the susceptibility to Etoposide | CTD | PMID:16217747 | Avpi1 | Rat | fipronil | increases expression | EXP | | 6480464 | fipronil results in increased expression of AVPI1 mRNA | CTD | PMID:23962444 | Avpi1 | Rat | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of AVPI1 mRNA | CTD | PMID:24136188 | Avpi1 | Rat | folic acid | multiple interactions | ISO | Avpi1 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of AVPI1 mRNA; [Methionine deficiency co-treated more ... | CTD | PMID:20938992|PMID:22206623 | Avpi1 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of AVPI1 mRNA | CTD | PMID:33387578 | Avpi1 | Rat | L-methionine | multiple interactions | ISO | Avpi1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression more ... | CTD | PMID:20938992 | Avpi1 | Rat | methyl methanesulfonate | increases expression | ISO | AVPI1 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of AVPI1 mRNA | CTD | PMID:23649840 | Avpi1 | Rat | mitomycin C | affects response to substance | ISO | AVPI1 (Homo sapiens) | 6480464 | AVPI1 protein affects the susceptibility to Mitomycin | CTD | PMID:16217747 | Avpi1 | Rat | mono(2-ethylhexyl) phthalate | decreases expression | ISO | Avpi1 (Mus musculus) | 6480464 | mono-(2-ethylhexyl)phthalate results in decreased expression of AVPI1 mRNA | CTD | PMID:22401849 | Avpi1 | Rat | N-methyl-4-phenylpyridinium | increases expression | ISO | Avpi1 (Mus musculus) | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of AVPI1 mRNA | CTD | PMID:22776087 | Avpi1 | Rat | N-methyl-4-phenylpyridinium | increases expression | ISO | AVPI1 (Homo sapiens) | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of AVPI1 mRNA | CTD | PMID:24810058 | Avpi1 | Rat | niclosamide | increases expression | ISO | AVPI1 (Homo sapiens) | 6480464 | Niclosamide results in increased expression of AVPI1 mRNA | CTD | PMID:36318118 | Avpi1 | Rat | okadaic acid | increases expression | ISO | AVPI1 (Homo sapiens) | 6480464 | Okadaic Acid results in increased expression of AVPI1 mRNA | CTD | PMID:38832940 | Avpi1 | Rat | ozone | multiple interactions | ISO | Avpi1 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased more ... | CTD | PMID:34911549 | Avpi1 | Rat | paracetamol | affects expression | ISO | Avpi1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of AVPI1 mRNA | CTD | PMID:17562736 | Avpi1 | Rat | paracetamol | increases expression | ISO | AVPI1 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of AVPI1 mRNA | CTD | PMID:21420995 | Avpi1 | Rat | paraquat | increases expression | EXP | | 6480464 | Paraquat results in increased expression of AVPI1 mRNA | CTD | PMID:32680482 | Avpi1 | Rat | PCB138 | multiple interactions | ISO | Avpi1 (Mus musculus) | 6480464 | [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... | CTD | PMID:25510870 | Avpi1 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Avpi1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Pectins] results in increased expression of AVPI1 mRNA | CTD | PMID:36331819 | Avpi1 | Rat | phenobarbital | affects expression | ISO | AVPI1 (Homo sapiens) | 6480464 | Phenobarbital affects the expression of AVPI1 mRNA | CTD | PMID:19159669 | Avpi1 | Rat | phenylephrine | increases expression | EXP | | 6480464 | Phenylephrine results in increased expression of AVPI1 mRNA | CTD | PMID:18158353 | Avpi1 | Rat | piroxicam | multiple interactions | ISO | AVPI1 (Homo sapiens) | 6480464 | Cisplatin promotes the reaction [Piroxicam results in decreased expression of AVPI1 mRNA] | CTD | PMID:21858171 | Avpi1 | Rat | progesterone | multiple interactions | ISO | AVPI1 (Homo sapiens) | 6480464 | [Estradiol co-treated with Progesterone] results in increased expression of AVPI1 mRNA | CTD | PMID:20660070 | Avpi1 | Rat | progesterone | increases expression | EXP | | 6480464 | Progesterone results in increased expression of AVPI1 mRNA | CTD | PMID:20726854 | Avpi1 | Rat | silicon dioxide | increases expression | ISO | AVPI1 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of AVPI1 mRNA | CTD | PMID:25895662 | Avpi1 | Rat | silver atom | increases expression | ISO | Avpi1 (Mus musculus) | 6480464 | Silver results in increased expression of AVPI1 mRNA | CTD | PMID:27131904 | Avpi1 | Rat | silver(0) | increases expression | ISO | Avpi1 (Mus musculus) | 6480464 | Silver results in increased expression of AVPI1 mRNA | CTD | PMID:27131904 | Avpi1 | Rat | sodium arsenite | decreases expression | ISO | AVPI1 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of AVPI1 mRNA | CTD | PMID:38568856 | Avpi1 | Rat | tamoxifen | affects expression | ISO | Avpi1 (Mus musculus) | 6480464 | Tamoxifen affects the expression of AVPI1 mRNA | CTD | PMID:17555576 | Avpi1 | Rat | temozolomide | decreases expression | ISO | AVPI1 (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of AVPI1 mRNA | CTD | PMID:31758290 | Avpi1 | Rat | testosterone | decreases expression | ISO | AVPI1 (Homo sapiens) | 6480464 | Testosterone results in decreased expression of AVPI1 mRNA | CTD | PMID:33359661 | Avpi1 | Rat | tetrachloroethene | decreases expression | ISO | Avpi1 (Mus musculus) | 6480464 | Tetrachloroethylene results in decreased expression of AVPI1 mRNA | CTD | PMID:28973375 | Avpi1 | Rat | tetrachloromethane | increases expression | ISO | Avpi1 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of AVPI1 mRNA | CTD | PMID:27339419|PMID:31919559 | Avpi1 | Rat | thiram | decreases expression | ISO | AVPI1 (Homo sapiens) | 6480464 | Thiram results in decreased expression of AVPI1 mRNA | CTD | PMID:38568856 | Avpi1 | Rat | triphenyl phosphate | increases expression | EXP | | 6480464 | triphenyl phosphate results in increased expression of AVPI1 mRNA | CTD | PMID:30589522 | Avpi1 | Rat | triphenyl phosphate | affects expression | ISO | AVPI1 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of AVPI1 mRNA | CTD | PMID:37042841 | Avpi1 | Rat | troglitazone | increases expression | ISO | Avpi1 (Mus musculus) | 6480464 | troglitazone results in increased expression of AVPI1 mRNA | CTD | PMID:28973697 | Avpi1 | Rat | urethane | increases expression | ISO | AVPI1 (Homo sapiens) | 6480464 | Urethane results in increased expression of AVPI1 mRNA | CTD | PMID:28818685 | Avpi1 | Rat | valproic acid | decreases methylation | ISO | AVPI1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of AVPI1 gene | CTD | PMID:29154799 | Avpi1 | Rat | valproic acid | increases expression | ISO | AVPI1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of AVPI1 mRNA | CTD | PMID:23527032|PMID:29154799 | Avpi1 | Rat | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of AVPI1 mRNA | CTD | PMID:22570695 | Avpi1 | Rat | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of AVPI1 mRNA | CTD | PMID:23034163 | Avpi1 | Rat | zinc atom | multiple interactions | ISO | AVPI1 (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of AVPI1 mRNA | CTD | PMID:18593933 | Avpi1 | Rat | zinc(0) | multiple interactions | ISO | AVPI1 (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of AVPI1 mRNA | CTD | PMID:18593933 | Avpi1 | Rat | zoledronic acid | decreases expression | ISO | AVPI1 (Homo sapiens) | 6480464 | zoledronic acid results in decreased expression of AVPI1 mRNA | CTD | PMID:24714768 | | |||||||||






















