Gpr176 (G protein-coupled receptor 176) - Rat Genome Database

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Gene: Gpr176 (G protein-coupled receptor 176) Rattus norvegicus
Analyze
Symbol: Gpr176
Name: G protein-coupled receptor 176
RGD ID: 621718
Description: Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and circadian behavior. Predicted to act upstream of or within adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human GPR176 (G protein-coupled receptor 176); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: G-protein coupled receptor AGR9; gene model 1012, (NCBI); Gm1012; Gpr; probable G-protein coupled receptor 176; putative G protein coupled receptor; RBU-15
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83125,690,750 - 125,791,172 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3125,690,751 - 125,791,172 (-)EnsemblGRCr8
mRatBN7.23105,236,794 - 105,337,664 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3105,236,795 - 105,337,226 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3108,902,124 - 109,003,886 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03117,497,650 - 117,599,415 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03115,158,025 - 115,259,793 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03110,042,853 - 110,140,756 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3110,042,853 - 110,140,756 (-)Ensemblrn6Rnor6.0
Rnor_5.03116,588,548 - 116,686,465 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43104,699,853 - 104,801,217 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3104,154,931 - 104,254,445 (-)NCBICelera
RGSC_v3.13104,596,280 - 104,603,263 (-)NCBI
Cytogenetic Map3q35NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
1,2-dichloroethane  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
4,4'-sulfonyldiphenol  (EXP)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
amphetamine  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
Azoxymethane  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
cadmium atom  (EXP)
cadmium dichloride  (EXP)
capsaicin  (EXP)
carbon nanotube  (ISO)
CGP 52608  (ISO)
choline  (ISO)
cisplatin  (EXP,ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
diclofenac  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
fenvalerate  (EXP)
ferroheme b  (ISO)
folic acid  (ISO)
furan  (EXP)
genistein  (ISO)
gentamycin  (EXP)
heme b  (ISO)
L-methionine  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methimazole  (EXP)
methylmercury chloride  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
oxaliplatin  (EXP)
ozone  (ISO)
paraquat  (EXP)
perfluorohexanesulfonic acid  (ISO)
phenylmercury acetate  (ISO)
potassium chromate  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
testosterone  (EXP)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
trichloroethene  (EXP)
triclosan  (ISO)
trovafloxacin  (ISO)
valproic acid  (ISO)
vincaleukoblastine  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IEA)
plasma membrane  (IBA,IEA,ISO,ISS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. cDNA cloning of a putative G protein-coupled receptor from brain. Hata S, etal., Biochim Biophys Acta 1995 Mar 14;1261(1):121-5.
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8018717   PMID:26882873  


Genomics

Comparative Map Data
Gpr176
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83125,690,750 - 125,791,172 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3125,690,751 - 125,791,172 (-)EnsemblGRCr8
mRatBN7.23105,236,794 - 105,337,664 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3105,236,795 - 105,337,226 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3108,902,124 - 109,003,886 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03117,497,650 - 117,599,415 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03115,158,025 - 115,259,793 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03110,042,853 - 110,140,756 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3110,042,853 - 110,140,756 (-)Ensemblrn6Rnor6.0
Rnor_5.03116,588,548 - 116,686,465 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43104,699,853 - 104,801,217 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3104,154,931 - 104,254,445 (-)NCBICelera
RGSC_v3.13104,596,280 - 104,603,263 (-)NCBI
Cytogenetic Map3q35NCBI
GPR176
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381539,799,008 - 39,920,266 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1539,799,008 - 39,920,936 (-)Ensemblhg38GRCh38
GRCh371540,091,209 - 40,212,467 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361537,880,223 - 38,000,385 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341537,880,222 - 38,000,385NCBI
Celera1516,856,199 - 16,976,371 (-)NCBICelera
Cytogenetic Map15q14-q15.1NCBI
HuRef1516,935,032 - 17,057,623 (-)NCBIHuRef
CHM1_11540,210,585 - 40,332,721 (-)NCBICHM1_1
T2T-CHM13v2.01537,604,203 - 37,725,586 (-)NCBIT2T-CHM13v2.0
Gpr176
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392118,107,577 - 118,205,022 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2118,107,591 - 118,203,900 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm382118,277,096 - 118,374,549 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2118,277,110 - 118,373,419 (-)Ensemblmm10GRCm38
MGSCv372118,102,834 - 118,199,155 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv362117,968,551 - 118,064,752 (-)NCBIMGSCv36mm8
Celera2119,421,829 - 119,523,000 (-)NCBICelera
Cytogenetic Map2E5NCBI
cM Map259.4NCBI
Gpr176
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554166,735,636 - 6,878,982 (-)Ensembl
ChiLan1.0NW_0049554166,735,790 - 6,879,078 (-)NCBIChiLan1.0ChiLan1.0
GPR176
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21629,039,137 - 29,157,861 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11533,190,322 - 33,309,919 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01518,739,092 - 18,858,618 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11536,995,149 - 37,114,516 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1536,995,149 - 37,007,073 (-)EnsemblpanPan2panpan1.1
GPR176
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1306,990,463 - 7,120,361 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl306,992,849 - 7,119,992 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha307,045,213 - 7,174,733 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0307,116,881 - 7,246,688 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl307,116,890 - 7,247,495 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1307,040,657 - 7,171,678 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0307,146,150 - 7,276,513 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0307,275,692 - 7,406,107 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Gpr176
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864085,450,184 - 85,565,052 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364713,298,139 - 3,413,095 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364713,298,247 - 3,413,093 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GPR176
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1131,365,180 - 131,494,959 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11131,355,332 - 131,494,967 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21146,588,375 - 146,671,430 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GPR176
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12643,085,416 - 43,205,075 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604897,749,543 - 97,870,064 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gpr176
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248047,119,323 - 7,248,778 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248047,119,104 - 7,249,561 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Gpr176
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1596,425,031 - 96,520,066 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Gpr176
633 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:777
Count of miRNA genes:303
Interacting mature miRNAs:393
Transcripts:ENSRNOT00000007882
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)396509147141509147Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)373592512136118980Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)373592512136118980Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)351581665184004958Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)367641776167835660Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)358601291153936591Rat
1582216Bw65Body weight QTL 656.3body mass (VT:0001259)body weight (CMO:0000012)3122654702136118980Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)349872657138829559Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)373592512136118980Rat
1582219Bw63Body weight QTL 633.80.001body mass (VT:0001259)body weight (CMO:0000012)3116582412136118980Rat
1582221Kidm30Kidney mass QTL 303.50.0008kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)385062224136118980Rat
1582210Bw71Body weight QTL 713.30.0012body mass (VT:0001259)body weight (CMO:0000012)385062224136118980Rat
7387306Bw124Body weight QTL 1243.20.0003body mass (VT:0001259)body weight (CMO:0000012)3104545086149545086Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)381425008141509147Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)370845569136091483Rat
1600376Arunc5Aerobic running capacity QTL 50.21exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)393829559138829559Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)3112250810157250810Rat
2302273Gluco35Glucose level QTL 355.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)3101255536134750886Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)379649560177741895Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)367641995130815812Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)396509147141509147Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)3117537367162537367Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3125116475170116475Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3110225882155225882Rat
631200Cm25Cardiac mass QTL 254.80.0001heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)381541464126563126Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)390755164141509147Rat
5686842Rf59Renal function QTL 59urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)3122395989167395989Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31141509147Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)398651826167012663Rat
1331758Bp207Blood pressure QTL 2072.848arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3110634702155634702Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35675975141509147Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)367641995130815812Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)3116188400161188400Rat

Markers in Region
RH144016  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23105,337,357 - 105,337,497 (+)MAPPERmRatBN7.2
Rnor_6.03110,140,888 - 110,141,027NCBIRnor6.0
Rnor_5.03116,686,597 - 116,686,736UniSTSRnor5.0
RGSC_v3.43104,801,339 - 104,801,478UniSTSRGSC3.4
Celera3104,254,577 - 104,254,716UniSTS
RH 3.4 Map3915.5UniSTS
Cytogenetic Map3q35UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 147 84 83 52 87 52 6 344 187 11 126 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000007882   ⟹   ENSRNOP00000007882
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3125,690,751 - 125,791,172 (-)Ensembl
mRatBN7.2 Ensembl3105,236,795 - 105,337,226 (-)Ensembl
Rnor_6.0 Ensembl3110,042,853 - 110,140,756 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000166976   ⟹   ENSRNOP00000100020
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3125,690,751 - 125,790,862 (-)Ensembl
RefSeq Acc Id: NM_001270986   ⟹   NP_001257915
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83125,690,751 - 125,791,172 (-)NCBI
mRatBN7.23105,236,795 - 105,337,226 (-)NCBI
Rnor_6.03110,042,853 - 110,140,756 (-)NCBI
Rnor_5.03116,588,548 - 116,686,465 (-)NCBI
Celera3104,154,931 - 104,254,445 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017591434   ⟹   XP_017446923
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83125,690,750 - 125,790,960 (-)NCBI
mRatBN7.23105,236,794 - 105,337,664 (-)NCBI
Rnor_6.03110,042,973 - 110,140,470 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039104128   ⟹   XP_038960056
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83125,690,750 - 125,711,440 (-)NCBI
mRatBN7.23105,236,794 - 105,257,360 (-)NCBI
RefSeq Acc Id: XM_039104129   ⟹   XP_038960057
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83125,690,750 - 125,790,950 (-)NCBI
mRatBN7.23105,236,794 - 105,337,660 (-)NCBI
RefSeq Acc Id: XM_039104132   ⟹   XP_038960060
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83125,690,750 - 125,790,950 (-)NCBI
mRatBN7.23105,236,794 - 105,336,985 (-)NCBI
RefSeq Acc Id: XM_063283010   ⟹   XP_063139080
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83125,690,750 - 125,790,960 (-)NCBI
RefSeq Acc Id: XM_063283011   ⟹   XP_063139081
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83125,690,750 - 125,790,940 (-)NCBI
RefSeq Acc Id: XM_063283012   ⟹   XP_063139082
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83125,690,750 - 125,729,595 (-)NCBI
RefSeq Acc Id: XM_063283013   ⟹   XP_063139083
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83125,690,750 - 125,729,595 (-)NCBI
RefSeq Acc Id: NP_001257915   ⟸   NM_001270986
- UniProtKB: Q63231 (UniProtKB/Swiss-Prot),   Q64017 (UniProtKB/Swiss-Prot),   A6HPA4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017446923   ⟸   XM_017591434
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000007882   ⟸   ENSRNOT00000007882
RefSeq Acc Id: XP_038960057   ⟸   XM_039104129
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038960060   ⟸   XM_039104132
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038960056   ⟸   XM_039104128
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063139080   ⟸   XM_063283010
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063139081   ⟸   XM_063283011
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063139083   ⟸   XM_063283013
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063139082   ⟸   XM_063283012
- Peptide Label: isoform X4
Ensembl Acc Id: ENSRNOP00000100020   ⟸   ENSRNOT00000166976
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q64017-F1-model_v2 AlphaFold Q64017 1-513 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692307
Promoter ID:EPDNEW_R2831
Type:initiation region
Name:Gpr176_1
Description:G protein-coupled receptor 176
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03110,140,713 - 110,140,773EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621718 AgrOrtholog
BioCyc Gene G2FUF-48256 BioCyc
Ensembl Genes ENSRNOG00000005971 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000007882 ENTREZGENE
  ENSRNOT00000007882.5 UniProtKB/Swiss-Prot
  ENSRNOT00000166976 ENTREZGENE
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot
InterPro GPCR_176_Rhodpsn_7TM UniProtKB/Swiss-Prot
  GPCR_Rhodpsn UniProtKB/Swiss-Prot
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot
KEGG Report rno:117257 UniProtKB/Swiss-Prot
NCBI Gene 117257 ENTREZGENE
PANTHER G PROTEIN-COUPLED RECEPTOR UniProtKB/Swiss-Prot
  G-PROTEIN COUPLED RECEPTOR 176 UniProtKB/Swiss-Prot
Pfam 7tm_1 UniProtKB/Swiss-Prot
PhenoGen Gpr176 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/Swiss-Prot
PROSITE G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000005971 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot
UniProt A0ABK0LA46_RAT UniProtKB/TrEMBL
  A6HPA4 ENTREZGENE, UniProtKB/TrEMBL
  GP176_RAT UniProtKB/Swiss-Prot
  Q63231 ENTREZGENE
  Q64017 ENTREZGENE
UniProt Secondary Q63231 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Gpr176  G protein-coupled receptor 176  Gm1012  gene model 1012, (NCBI)  Symbol and Name updated 1299863 APPROVED
2004-09-10 Gm1012  gene model 1012, (NCBI)  Gpr  putative G protein coupled receptor  Symbol and Name updated 1299863 APPROVED
2002-08-07 Gpr  putative G protein coupled receptor      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_domains contains four putative glycosylation sites in the N-terminal part, seven transmembrane domains, and a large cytosolic domain in the C-terminal part 632864