Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (1->4)-beta-D-glucan | multiple interactions | ISO | Grin3b (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of GRIN3B mRNA | CTD | PMID:36331819 | 17beta-estradiol | affects expression | ISO | GRIN3B (Homo sapiens) | 6480464 | Estradiol affects the expression of GRIN3B mRNA | CTD | PMID:22574217 | 17beta-estradiol | multiple interactions | ISO | GRIN3B (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in increased expression of GRIN3B mRNA | CTD | PMID:30165855 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of GRIN3B mRNA | CTD | PMID:33387578 | 4,4'-sulfonyldiphenol | decreases methylation | ISO | Grin3b (Mus musculus) | 6480464 | bisphenol S results in decreased methylation of GRIN3B promoter | CTD | PMID:33297965 | 4,4'-sulfonyldiphenol | affects methylation | ISO | Grin3b (Mus musculus) | 6480464 | bisphenol S affects the methylation of GRIN3B gene | CTD | PMID:31683443 | 4,4'-sulfonyldiphenol | decreases expression | ISO | GRIN3B (Homo sapiens) | 6480464 | bisphenol S results in decreased expression of GRIN3B mRNA | CTD | PMID:34979203 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of GRIN3B mRNA | CTD | PMID:24780913 | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of GRIN3B mRNA | CTD | PMID:31881176 | aflatoxin B1 | increases methylation | ISO | GRIN3B (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of GRIN3B intron | CTD | PMID:30157460 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of GRIN3B mRNA | CTD | PMID:16483693 | atrazine | affects methylation | EXP | | 6480464 | Atrazine affects the methylation of GRIN3B gene | CTD | PMID:28931070 | benzo[a]pyrene | multiple interactions | ISO | Grin3b (Mus musculus) | 6480464 | Benzo(a)pyrene promotes the reaction [AHR protein binds to GRIN3B promoter] | CTD | PMID:19654925 | benzo[a]pyrene | decreases methylation | ISO | Grin3b (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased methylation of GRIN3B exon | CTD | PMID:27901495 | benzo[a]pyrene | increases methylation | ISO | GRIN3B (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of GRIN3B exon | CTD | PMID:27901495 | bisphenol A | decreases expression | ISO | Grin3b (Mus musculus) | 6480464 | bisphenol A results in decreased expression of GRIN3B mRNA | CTD | PMID:25270620 and PMID:38074096 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of GRIN3B mRNA | CTD | PMID:25181051 | cadmium dichloride | increases methylation | EXP | | 6480464 | Cadmium Chloride results in increased methylation of GRIN3B promoter | CTD | PMID:22457795 | celecoxib | multiple interactions | ISO | Grin3b (Mus musculus) | 6480464 | Celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIN3B mRNA] | CTD | PMID:21589914 | chlorpyrifos | decreases expression | EXP | | 6480464 | Chlorpyrifos results in decreased expression of GRIN3B mRNA | CTD | PMID:19440498 | cisplatin | increases expression | ISO | GRIN3B (Homo sapiens) | 6480464 | Cisplatin results in increased expression of GRIN3B mRNA | CTD | PMID:27392435 | cisplatin | multiple interactions | ISO | GRIN3B (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of GRIN3B mRNA | CTD | PMID:27392435 | cocaine | affects expression | EXP | | 6480464 | Cocaine affects the expression of GRIN3B protein | CTD | PMID:15140200 | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of GRIN3B mRNA | CTD | PMID:26577399 | dexamethasone | decreases expression | EXP | | 6480464 | Dexamethasone results in decreased expression of GRIN3B mRNA | CTD | PMID:20032058 | dexamethasone | multiple interactions | EXP | | 6480464 | Testosterone inhibits the reaction [Dexamethasone results in decreased expression of GRIN3B mRNA] | CTD | PMID:20032058 | dieldrin | affects expression | EXP | | 6480464 | Dieldrin affects the expression of GRIN3B mRNA | CTD | PMID:19440498 | dioxygen | increases expression | ISO | GRIN3B (Homo sapiens) | 6480464 | Oxygen deficiency results in increased expression of GRIN3B mRNA | CTD | PMID:26516004 | endosulfan | increases expression | EXP | | 6480464 | Endosulfan results in increased expression of GRIN3B mRNA | CTD | PMID:29391264 | ethanol | decreases expression | EXP | | 6480464 | Ethanol results in decreased expression of GRIN3B mRNA | CTD | PMID:20655511 | fenvalerate | increases expression | EXP | | 6480464 | fenvalerate results in increased expression of GRIN3B mRNA | CTD | PMID:30307764 | gentamycin | affects expression | EXP | | 6480464 | Gentamicins affects the expression of GRIN3B mRNA | CTD | PMID:33387578 | haloperidol | increases expression | EXP | | 6480464 | Haloperidol results in increased expression of GRIN3B mRNA | CTD | PMID:15860345 | iron dichloride | decreases expression | ISO | GRIN3B (Homo sapiens) | 6480464 | ferrous chloride results in decreased expression of GRIN3B mRNA | CTD | PMID:35984750 | kainic acid | decreases expression | ISO | Grin3b (Mus musculus) | 6480464 | Kainic Acid results in decreased expression of GRIN3B mRNA | CTD | PMID:21589914 | kainic acid | multiple interactions | ISO | Grin3b (Mus musculus) | 6480464 | celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIN3B mRNA] | CTD | PMID:21589914 | lead diacetate | increases expression | EXP | | 6480464 | lead acetate results in increased expression of GRIN3B mRNA | CTD | PMID:22160880 | lead diacetate | increases expression | ISO | Grin3b (Mus musculus) | 6480464 | lead acetate results in increased expression of GRIN3B mRNA | CTD | PMID:24260418 | methotrexate | affects response to substance | ISO | GRIN3B (Homo sapiens) | 6480464 | GRIN3B protein affects the susceptibility to Methotrexate | CTD | PMID:16217747 | mono(2-ethylhexyl) phthalate | decreases expression | ISO | Grin3b (Mus musculus) | 6480464 | mono-(2-ethylhexyl)phthalate results in decreased expression of GRIN3B mRNA | CTD | PMID:22401849 | nickel atom | increases expression | EXP | | 6480464 | Nickel results in increased expression of GRIN3B mRNA | CTD | PMID:19440498 | ozone | multiple interactions | ISO | GRIN3B (Homo sapiens) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the expression of GRIN3B mRNA | CTD | PMID:35430440 | paracetamol | affects expression | ISO | Grin3b (Mus musculus) | 6480464 | Acetaminophen affects the expression of GRIN3B mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of GRIN3B mRNA | CTD | PMID:33387578 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Grin3b (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of GRIN3B mRNA | CTD | PMID:36331819 | propanal | increases expression | ISO | GRIN3B (Homo sapiens) | 6480464 | propionaldehyde results in increased expression of GRIN3B mRNA | CTD | PMID:26079696 | rotenone | increases expression | ISO | GRIN3B (Homo sapiens) | 6480464 | Rotenone results in increased expression of GRIN3B mRNA | CTD | PMID:29955902 | sodium arsenite | decreases expression | ISO | GRIN3B (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of GRIN3B mRNA | CTD | PMID:29301061 and PMID:34032870 | tamoxifen | decreases expression | ISO | Grin3b (Mus musculus) | 6480464 | Tamoxifen results in decreased expression of GRIN3B mRNA | CTD | PMID:25123088 | testosterone | multiple interactions | EXP | | 6480464 | Testosterone inhibits the reaction [Dexamethasone results in decreased expression of GRIN3B mRNA] | CTD | PMID:20032058 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of GRIN3B mRNA | CTD | PMID:34492290 | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of GRIN3B mRNA | CTD | PMID:33387578 | triptonide | affects expression | ISO | Grin3b (Mus musculus) | 6480464 | triptonide affects the expression of GRIN3B mRNA | CTD | PMID:33045310 | trovafloxacin | increases expression | ISO | Grin3b (Mus musculus) | 6480464 | trovafloxacin results in increased expression of GRIN3B mRNA | CTD | PMID:35537566 | valproic acid | increases methylation | ISO | GRIN3B (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of GRIN3B gene | CTD | PMID:29154799 | valproic acid | increases expression | EXP | | 6480464 | Valproic Acid results in increased expression of GRIN3B mRNA | CTD | PMID:34779009 | |