Rassf5 (Ras association domain family member 5) - Rat Genome Database

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Gene: Rassf5 (Ras association domain family member 5) Rattus norvegicus
Analyze
Symbol: Rassf5
Name: Ras association domain family member 5
RGD ID: 621694
Description: Predicted to enable identical protein binding activity. Predicted to be involved in signal transduction. Predicted to act upstream of or within negative regulation of lymphocyte proliferation; positive regulation of protein ubiquitination; and regulation of protein localization to nucleus. Predicted to be located in cytoplasm and microtubule. Predicted to be active in nucleus. Orthologous to human RASSF5 (Ras association domain family member 5); PARTICIPATES IN lung non-small cell carcinoma pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Maxp1; new ras effector 1; Nore1; novel ras effector 1; protein interacting with guanine nucleotide exchange factor; Ras association (RalGDS/AF-6) domain family 5; Ras association (RalGDS/AF-6) domain family member 5; ras association domain-containing protein 5
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81345,189,768 - 45,255,277 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1345,189,804 - 45,255,277 (-)EnsemblGRCr8
mRatBN7.21342,637,513 - 42,703,024 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1342,637,549 - 42,703,024 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1345,244,277 - 45,311,065 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01346,532,408 - 46,599,197 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01343,796,450 - 43,862,915 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1344,567,621 - 44,634,401 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive1344,799,864 - 44,866,652 (-)NCBILyon_Normotensive
Lyon_Hypertensive1344,765,376 - 44,832,158 (-)NCBILyon_Hypertensive
F344_StmMcwi1344,719,228 - 44,786,026 (-)NCBIF344_StmMcwi
Rnor_6.01347,956,754 - 48,022,333 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1347,956,790 - 48,022,333 (-)Ensemblrn6Rnor6.0
Rnor_5.01353,032,680 - 53,098,045 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41344,121,863 - 44,188,493 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1342,983,422 - 43,048,730 (-)NCBICelera
RGSC_v3.11344,135,904 - 44,202,536 (-)NCBI
RH 3.4 Map13201.8RGD
Cytogenetic Map13q13NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
8-Br-cAMP  (ISO)
acetamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
cisplatin  (EXP,ISO)
cobalt dichloride  (ISO)
crocidolite asbestos  (ISO)
daidzein  (ISO)
daidzein 7-O-beta-D-glucoside  (ISO)
DDE  (ISO)
diazinon  (ISO)
Dibutyl phosphate  (ISO)
dioxygen  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
ethanol  (ISO)
flavonoids  (EXP)
folic acid  (ISO)
genistein  (ISO)
genistein 7-O-beta-D-glucoside  (ISO)
gentamycin  (EXP)
glycitein  (ISO)
glycitin  (ISO)
glyphosate  (EXP)
hemin  (ISO)
hydroquinone  (ISO)
ketamine  (EXP)
L-methionine  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methyl methanesulfonate  (ISO)
methylmercury(1+)  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
nickel atom  (ISO)
ochratoxin A  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
perfluorohexanesulfonic acid  (ISO)
permethrin  (EXP)
phenobarbital  (ISO)
pirinixic acid  (ISO)
progesterone  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sulforaphane  (ISO)
tamoxifen  (ISO)
testosterone  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
tributylstannane  (ISO)
Tributyltin oxide  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
valproic acid  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
cytoskeleton  (IEA)
microtubule  (IEA)
nucleus  (IBA,IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence. Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Information Derived from GenBank Report RGD, Sept. 2003
10. Suppression of hydroxyurea-induced centrosome amplification by NORE1A and down-regulation of NORE1A mRNA expression in non-small cell lung carcinoma. Shinmura K, etal., Lung Cancer. 2011 Jan;71(1):19-27. doi: 10.1016/j.lungcan.2010.04.006.
11. The pro-apoptotic Ras effector Nore1 may serve as a Ras-regulated tumor suppressor in the lung. Vos MD, etal., J Biol Chem 2003 Jun 13;278(24):21938-43. Epub 2003 Apr 3.
Additional References at PubMed
PMID:11978988   PMID:17517604   PMID:21194982   PMID:21938476   PMID:22173032   PMID:24165023  


Genomics

Comparative Map Data
Rassf5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81345,189,768 - 45,255,277 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1345,189,804 - 45,255,277 (-)EnsemblGRCr8
mRatBN7.21342,637,513 - 42,703,024 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1342,637,549 - 42,703,024 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1345,244,277 - 45,311,065 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01346,532,408 - 46,599,197 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01343,796,450 - 43,862,915 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1344,567,621 - 44,634,401 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive1344,799,864 - 44,866,652 (-)NCBILyon_Normotensive
Lyon_Hypertensive1344,765,376 - 44,832,158 (-)NCBILyon_Hypertensive
F344_StmMcwi1344,719,228 - 44,786,026 (-)NCBIF344_StmMcwi
Rnor_6.01347,956,754 - 48,022,333 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1347,956,790 - 48,022,333 (-)Ensemblrn6Rnor6.0
Rnor_5.01353,032,680 - 53,098,045 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41344,121,863 - 44,188,493 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1342,983,422 - 43,048,730 (-)NCBICelera
RGSC_v3.11344,135,904 - 44,202,536 (-)NCBI
RH 3.4 Map13201.8RGD
Cytogenetic Map13q13NCBI
RASSF5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381206,507,531 - 206,589,448 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1206,507,531 - 206,589,448 (+)Ensemblhg38GRCh38
GRCh371206,680,864 - 206,762,780 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361204,747,502 - 204,829,239 (+)NCBIBuild 36Build 36hg18NCBI36
Celera1179,932,333 - 180,014,065 (+)NCBICelera
Cytogenetic Map1q32.1NCBI
HuRef1177,379,199 - 177,460,931 (+)NCBIHuRef
CHM1_11207,953,085 - 208,034,823 (+)NCBICHM1_1
T2T-CHM13v2.01205,771,712 - 205,853,623 (+)NCBIT2T-CHM13v2.0
Rassf5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391131,104,147 - 131,172,915 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1131,104,147 - 131,172,995 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381131,176,410 - 131,245,178 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1131,176,410 - 131,245,258 (-)Ensemblmm10GRCm38
MGSCv371133,072,987 - 133,141,755 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361133,003,956 - 133,072,724 (-)NCBIMGSCv36mm8
Celera1133,798,687 - 133,867,483 (-)NCBICelera
Cytogenetic Map1E4NCBI
cM Map156.91NCBI
Rassf5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540642,086,081 - 42,159,204 (+)Ensembl
ChiLan1.0NW_00495540642,086,081 - 42,159,204 (+)NCBIChiLan1.0ChiLan1.0
RASSF5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2142,787,046 - 42,871,019 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1142,752,573 - 42,836,547 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01182,107,396 - 182,191,346 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11186,388,571 - 186,471,134 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1186,388,571 - 186,471,134 (+)EnsemblpanPan2panpan1.1
RASSF5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1382,783,049 - 2,849,188 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl382,783,122 - 2,847,909 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha382,873,999 - 2,941,303 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0382,779,187 - 2,846,485 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl382,779,211 - 2,846,483 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1382,772,433 - 2,839,712 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0383,165,827 - 3,232,690 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0383,366,000 - 3,433,252 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Rassf5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934468,748,273 - 68,815,134 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365575,988,554 - 6,045,274 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365575,988,578 - 6,014,214 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RASSF5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl967,157,167 - 67,237,365 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1967,157,167 - 67,237,366 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2973,576,896 - 73,590,604 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RASSF5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12522,775,917 - 22,854,739 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2522,774,661 - 22,807,353 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605523,474,267 - 23,553,128 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rassf5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248074,837,730 - 4,905,711 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248074,837,106 - 4,905,717 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Rassf5
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1104,567,552 - 4,631,853 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Rassf5
488 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:781
Count of miRNA genes:289
Interacting mature miRNAs:368
Transcripts:ENSRNOT00000008055
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10755495Bp387Blood pressure QTL 3873.78arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133721624190057603Rat
9589141Insul28Insulin level QTL 2810.820.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)131186625456866254Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1338975045103588154Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133992469384924693Rat
61391Bp5Blood pressure QTL 55.6arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)132485392569853925Rat
4889861Pur29Proteinuria QTL 2913.80.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133996821183286298Rat
1300163Cardf1Cardiac cell morphology QTL 14.18aorta morphology trait (VT:0000272)artery lesion measurement (CMO:0000975)131244842147969993Rat
2317040Aia21Adjuvant induced arthritis QTL 212.75joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)131238432057384320Rat
631645Bp121Blood pressure QTL 1213.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131746828262468282Rat
2317046Aia8Adjuvant induced arthritis QTL 83.9700000286102295joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)131238432057384320Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13742179187286911Rat
2303032Bp328Blood pressure QTL 328arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134373632747969993Rat
61339Bp24Blood pressure QTL 240.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13600200847359539Rat
1331784Bp222Blood pressure QTL 2222.944arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)132433543255601132Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133708798382087983Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)134098358585983585Rat
2302275Gluco37Glucose level QTL 373.8blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)131244842148744906Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1321120177109350286Rat
1558644Cm45Cardiac mass QTL 453.60.002heart mass (VT:0007028)heart wet weight (CMO:0000069)132624480871244808Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133379409678794096Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133992469384924693Rat
2303563Bw89Body weight QTL 896body mass (VT:0001259)body weight (CMO:0000012)133483494779834947Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1311081740103588154Rat
2301962Cm72Cardiac mass QTL 724.12heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)133379409660914504Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
12879471Bp398Blood pressure QTL 398arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)13308875548088755Rat
12879477Bp401Blood pressure QTL 401arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133981472684814726Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133996821184968211Rat
6893338Cm76Cardiac mass QTL 7600.99heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)132624480871244808Rat
11530006Niddm72Non-insulin dependent diabetes mellitus QTL 720.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)133828629883286298Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131103588154Rat
9589164Gluco66Glucose level QTL 666.670.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)131771133662711336Rat
7411662Foco29Food consumption QTL 2920.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)131186625456866254Rat

Markers in Region
RH134607  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21342,637,598 - 42,637,750 (+)MAPPERmRatBN7.2
Rnor_6.01347,956,840 - 47,956,991NCBIRnor6.0
Rnor_5.01353,032,766 - 53,032,917UniSTSRnor5.0
RGSC_v3.41344,121,912 - 44,122,063UniSTSRGSC3.4
Celera1342,983,471 - 42,983,622UniSTS
Cytogenetic Map13q13UniSTS
RH142382  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21342,639,455 - 42,639,611 (+)MAPPERmRatBN7.2
Rnor_6.01347,958,697 - 47,958,852NCBIRnor6.0
Rnor_5.01353,034,623 - 53,034,778UniSTSRnor5.0
RGSC_v3.41344,124,274 - 44,124,429UniSTSRGSC3.4
Celera1342,985,328 - 42,985,483UniSTS
RH 3.4 Map13201.8UniSTS
Cytogenetic Map13q13UniSTS
Nore1-pending  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21342,638,121 - 42,638,252 (+)MAPPERmRatBN7.2
Rnor_6.01347,957,363 - 47,957,493NCBIRnor6.0
Rnor_5.01353,033,289 - 53,033,419UniSTSRnor5.0
RGSC_v3.41344,122,435 - 44,122,565UniSTSRGSC3.4
Celera1342,983,994 - 42,984,124UniSTS
Cytogenetic Map13q13UniSTS
BF386245  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21342,637,335 - 42,637,508 (+)MAPPERmRatBN7.2
Rnor_6.01347,956,577 - 47,956,749NCBIRnor6.0
Rnor_5.01353,032,503 - 53,032,675UniSTSRnor5.0
RGSC_v3.41344,121,649 - 44,121,821UniSTSRGSC3.4
Celera1342,983,208 - 42,983,380UniSTS
RH 3.4 Map13110.8UniSTS
Cytogenetic Map13q13UniSTS
BE120661  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81345,210,940 - 45,211,133 (+)Marker Load Pipeline
mRatBN7.21342,658,685 - 42,658,878 (+)MAPPERmRatBN7.2
Rnor_6.01347,977,927 - 47,978,119NCBIRnor6.0
Rnor_5.01353,053,851 - 53,054,043UniSTSRnor5.0
RGSC_v3.41344,143,504 - 44,143,696UniSTSRGSC3.4
Celera1343,004,558 - 43,004,750UniSTS
RH 3.4 Map13110.1UniSTS
Cytogenetic Map13q13UniSTS
AU046422  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21342,655,218 - 42,655,438 (+)MAPPERmRatBN7.2
Rnor_6.01347,974,460 - 47,974,679NCBIRnor6.0
Rnor_5.01353,050,384 - 53,050,603UniSTSRnor5.0
RGSC_v3.41344,140,037 - 44,140,256UniSTSRGSC3.4
Celera1343,001,091 - 43,001,310UniSTS
Cytogenetic Map13q13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000008055   ⟹   ENSRNOP00000008055
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1345,189,804 - 45,255,277 (-)Ensembl
mRatBN7.2 Ensembl1342,637,549 - 42,703,024 (-)Ensembl
Rnor_6.0 Ensembl1347,956,790 - 48,022,333 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000080035   ⟹   ENSRNOP00000070574
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1345,189,804 - 45,212,758 (-)Ensembl
mRatBN7.2 Ensembl1342,637,549 - 42,660,592 (-)Ensembl
Rnor_6.0 Ensembl1347,958,645 - 47,979,797 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000095675   ⟹   ENSRNOP00000077087
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1345,189,804 - 45,243,337 (-)Ensembl
mRatBN7.2 Ensembl1342,637,549 - 42,691,082 (-)Ensembl
RefSeq Acc Id: NM_019365   ⟹   NP_062238
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81345,189,805 - 45,255,277 (-)NCBI
mRatBN7.21342,637,550 - 42,703,024 (-)NCBI
Dahl_SR_JrHsd1344,567,621 - 44,634,401 (-)NCBI
Lyon_Normotensive1344,799,864 - 44,866,652 (-)NCBI
Lyon_Hypertensive1344,765,376 - 44,832,158 (-)NCBI
F344_StmMcwi1344,719,228 - 44,786,026 (-)NCBI
Rnor_6.01347,956,791 - 48,022,333 (-)NCBI
Rnor_5.01353,032,680 - 53,098,045 (-)NCBI
RGSC_v3.41344,121,863 - 44,188,493 (-)RGD
Celera1342,983,422 - 43,048,730 (-)RGD
Sequence:
RefSeq Acc Id: XM_008769494   ⟹   XP_008767716
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81345,189,768 - 45,212,835 (-)NCBI
mRatBN7.21342,637,513 - 42,660,547 (-)NCBI
Rnor_6.01347,956,754 - 47,979,789 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_062238 (Get FASTA)   NCBI Sequence Viewer  
  XP_008767716 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB71821 (Get FASTA)   NCBI Sequence Viewer  
  EDM09831 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000008055
  ENSRNOP00000008055.3
  ENSRNOP00000070574
GenBank Protein O35141 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_062238   ⟸   NM_019365
- UniProtKB: O35141 (UniProtKB/Swiss-Prot),   A6IC16 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008767716   ⟸   XM_008769494
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JY99 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000070574   ⟸   ENSRNOT00000080035
Ensembl Acc Id: ENSRNOP00000008055   ⟸   ENSRNOT00000008055
Ensembl Acc Id: ENSRNOP00000077087   ⟸   ENSRNOT00000095675
Protein Domains
Phorbol-ester/DAG-type   Ras-associating   SARAH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O35141-F1-model_v2 AlphaFold O35141 1-413 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698794
Promoter ID:EPDNEW_R9319
Type:single initiation site
Name:Rassf5_1
Description:Ras association domain family member 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01348,022,250 - 48,022,310EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621694 AgrOrtholog
BioCyc Gene G2FUF-18354 BioCyc
Ensembl Genes ENSRNOG00000005342 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000008055 ENTREZGENE
  ENSRNOT00000008055.6 UniProtKB/Swiss-Prot
  ENSRNOT00000080035 ENTREZGENE
Gene3D-CATH 1.20.5.110 UniProtKB/Swiss-Prot
  3.30.60.20 UniProtKB/Swiss-Prot
  Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1 UniProtKB/Swiss-Prot
InterPro C-RASSF UniProtKB/Swiss-Prot
  C1-like_sf UniProtKB/Swiss-Prot
  PE/DAG-bd UniProtKB/Swiss-Prot
  RA_dom UniProtKB/Swiss-Prot
  RASSF5 UniProtKB/Swiss-Prot
  SARAH_dom UniProtKB/Swiss-Prot
  Ubiquitin-like_domsf UniProtKB/Swiss-Prot
KEGG Report rno:54355 UniProtKB/Swiss-Prot
NCBI Gene 54355 ENTREZGENE
PANTHER PTHR22738 UniProtKB/Swiss-Prot
  PTHR22738:SF9 UniProtKB/Swiss-Prot
Pfam C1_1 UniProtKB/Swiss-Prot
  Nore1-SARAH UniProtKB/Swiss-Prot
  PF00788 UniProtKB/Swiss-Prot
PhenoGen Rassf5 PhenoGen
PROSITE PS50200 UniProtKB/Swiss-Prot
  SARAH UniProtKB/Swiss-Prot
  ZF_DAG_PE_1 UniProtKB/Swiss-Prot
  ZF_DAG_PE_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000005342 RatGTEx
SMART SM00109 UniProtKB/Swiss-Prot
  SM00314 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF54236 UniProtKB/Swiss-Prot
  SSF57889 UniProtKB/Swiss-Prot
UniProt A0A0G2JY99 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5Y5W8_RAT UniProtKB/TrEMBL
  A6IC16 ENTREZGENE, UniProtKB/TrEMBL
  O35141 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-03 Rassf5  Ras association domain family member 5  Rassf5  Ras association (RalGDS/AF-6) domain family member 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-25 Rassf5  Ras association (RalGDS/AF-6) domain family member 5  Rassf5  Ras association (RalGDS/AF-6) domain family 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Rassf5  Ras association (RalGDS/AF-6) domain family 5  Maxp1  protein interacting with guanine nucleotide exchange factor  Symbol and Name updated 1299863 APPROVED
2002-08-07 Maxp1  protein interacting with guanine nucleotide exchange factor      Symbol and Name status set to provisional 70820 PROVISIONAL