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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Nr2f6 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Nr2f6 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of NR2F6 mRNA | CTD | PMID:36331819 | Nr2f6 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Nr2f6 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of NR2F6 mRNA | CTD | PMID:22206623 | Nr2f6 | Rat | 17beta-estradiol | increases expression | ISO | NR2F6 (Homo sapiens) | 6480464 | Estradiol results in increased expression of NR2F6 mRNA | CTD | PMID:31646340 | Nr2f6 | Rat | 17beta-estradiol | increases expression | EXP | | 6480464 | Estradiol results in increased expression of NR2F6 mRNA | CTD | PMID:32145629 | Nr2f6 | Rat | 17beta-estradiol | multiple interactions | ISO | NR2F6 (Homo sapiens) | 6480464 | Estradiol inhibits the reaction [Fulvestrant results in increased expression of NR2F6 mRNA] and Fulvestrant inhibits the reaction [Estradiol results in increased expression of NR2F6 mRNA] | CTD | PMID:31646340 | Nr2f6 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Nr2f6 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of NR2F6 mRNA | CTD | PMID:21570461 and PMID:24058054 | Nr2f6 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of NR2F6 mRNA | CTD | PMID:32109520 | Nr2f6 | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of NR2F6 mRNA | CTD | PMID:21346803 | Nr2f6 | Rat | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 6-dinitrotoluene affects the expression of NR2F6 mRNA | CTD | PMID:21346803 | Nr2f6 | Rat | 4,4'-sulfonyldiphenol | decreases expression | ISO | Nr2f6 (Mus musculus) | 6480464 | bisphenol S results in decreased expression of NR2F6 mRNA | CTD | PMID:32071231 | Nr2f6 | Rat | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of NR2F6 mRNA | CTD | PMID:36041667 | Nr2f6 | Rat | 4,4'-sulfonyldiphenol | increases methylation | ISO | NR2F6 (Homo sapiens) | 6480464 | bisphenol S results in increased methylation of NR2F6 gene | CTD | PMID:31601247 | Nr2f6 | Rat | 4,4'-sulfonyldiphenol | increases methylation | ISO | Nr2f6 (Mus musculus) | 6480464 | bisphenol S results in increased methylation of NR2F6 promoter | CTD | PMID:33297965 | Nr2f6 | Rat | 4-hydroxynon-2-enal | decreases expression | ISO | NR2F6 (Homo sapiens) | 6480464 | 4-hydroxy-2-nonenal results in decreased expression of NR2F6 mRNA | CTD | PMID:12419474 | Nr2f6 | Rat | 4-hydroxyphenyl retinamide | increases expression | ISO | Nr2f6 (Mus musculus) | 6480464 | Fenretinide results in increased expression of NR2F6 mRNA | CTD | PMID:28973697 | Nr2f6 | Rat | 4-tert-Octylphenol | increases expression | EXP | | 6480464 | 4-tert-octylphenol results in increased expression of NR2F6 mRNA | CTD | PMID:17011747 | Nr2f6 | Rat | aflatoxin B1 | affects expression | ISO | NR2F6 (Homo sapiens) | 6480464 | Aflatoxin B1 affects the expression of NR2F6 protein | CTD | PMID:20106945 | Nr2f6 | Rat | all-trans-retinoic acid | decreases expression | ISO | Nr2f6 (Mus musculus) | 6480464 | Tretinoin results in decreased expression of NR2F6 mRNA | CTD | PMID:16604517 | Nr2f6 | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of NR2F6 mRNA | CTD | PMID:16483693 | Nr2f6 | Rat | aristolochic acid A | increases expression | ISO | NR2F6 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of NR2F6 mRNA | CTD | PMID:33212167 | Nr2f6 | Rat | Aroclor 1254 | increases expression | ISO | Nr2f6 (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in increased expression of NR2F6 mRNA | CTD | PMID:23650126 | Nr2f6 | Rat | arsenite(3-) | increases expression | ISO | NR2F6 (Homo sapiens) | 6480464 | arsenite results in increased expression of NR2F6 mRNA | CTD | PMID:31646340 | Nr2f6 | Rat | arsenous acid | decreases expression | ISO | NR2F6 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of NR2F6 mRNA | CTD | PMID:20458559 | Nr2f6 | Rat | benzene | multiple interactions | EXP | | 6480464 | [Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in decreased expression of NR2F6 mRNA | CTD | PMID:17905399 | Nr2f6 | Rat | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of NR2F6 mRNA | CTD | PMID:21839799 | Nr2f6 | Rat | benzo[a]pyrene | decreases expression | ISO | NR2F6 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of NR2F6 mRNA | CTD | PMID:32234424 | Nr2f6 | Rat | benzo[a]pyrene | affects methylation | ISO | NR2F6 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of NR2F6 intron | CTD | PMID:30157460 | Nr2f6 | Rat | benzo[a]pyrene | multiple interactions | ISO | Nr2f6 (Mus musculus) | 6480464 | AHR protein affects the reaction [Benzo(a)pyrene affects the expression of NR2F6 mRNA] | CTD | PMID:22228805 | Nr2f6 | Rat | benzo[a]pyrene | decreases expression | ISO | Nr2f6 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of NR2F6 mRNA | CTD | PMID:20127859 more ... | Nr2f6 | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | NR2F6 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:19150397 | Nr2f6 | Rat | benzo[e]pyrene | increases methylation | ISO | NR2F6 (Homo sapiens) | 6480464 | benzo(e)pyrene results in increased methylation of NR2F6 intron | CTD | PMID:30157460 | Nr2f6 | Rat | bisphenol A | increases expression | ISO | Nr2f6 (Mus musculus) | 6480464 | bisphenol A results in increased expression of NR2F6 mRNA | CTD | PMID:26063408 more ... | Nr2f6 | Rat | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of NR2F6 mRNA | CTD | PMID:36041667 | Nr2f6 | Rat | bisphenol A | increases expression | ISO | NR2F6 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of NR2F6 mRNA | CTD | PMID:33670352 | Nr2f6 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of NR2F6 mRNA | CTD | PMID:32145629 | Nr2f6 | Rat | bisphenol A | decreases expression | ISO | Nr2f6 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of NR2F6 mRNA | CTD | PMID:32071231 and PMID:35598803 | Nr2f6 | Rat | bisphenol A | affects methylation | ISO | Nr2f6 (Mus musculus) | 6480464 | bisphenol A affects the methylation of NR2F6 promoter | CTD | PMID:27334623 | Nr2f6 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of NR2F6 mRNA | CTD | PMID:25181051 | Nr2f6 | Rat | bisphenol F | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of NR2F6 mRNA | CTD | PMID:36041667 | Nr2f6 | Rat | butanal | decreases expression | ISO | NR2F6 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of NR2F6 mRNA | CTD | PMID:26079696 | Nr2f6 | Rat | cadmium atom | increases expression | ISO | NR2F6 (Homo sapiens) | 6480464 | Cadmium results in increased expression of NR2F6 mRNA | CTD | PMID:31646340 | Nr2f6 | Rat | cadmium dichloride | decreases expression | ISO | NR2F6 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of NR2F6 mRNA | CTD | PMID:38382870 and PMID:38568856 | Nr2f6 | Rat | caffeine | increases phosphorylation | ISO | NR2F6 (Homo sapiens) | 6480464 | Caffeine results in increased phosphorylation of NR2F6 protein | CTD | PMID:35688186 | Nr2f6 | Rat | carbamazepine | affects expression | ISO | NR2F6 (Homo sapiens) | 6480464 | Carbamazepine affects the expression of NR2F6 mRNA | CTD | PMID:24752500 | Nr2f6 | Rat | carbon nanotube | decreases expression | ISO | Nr2f6 (Mus musculus) | 6480464 | Nanotubes and Carbon analog results in decreased expression of NR2F6 mRNA | CTD | PMID:25620056 | Nr2f6 | Rat | clofibrate | decreases expression | ISO | Nr2f6 (Mus musculus) | 6480464 | Clofibrate results in decreased expression of NR2F6 mRNA | CTD | PMID:17585979 | Nr2f6 | Rat | copper(II) sulfate | decreases expression | ISO | NR2F6 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of NR2F6 mRNA | CTD | PMID:19549813 | Nr2f6 | Rat | coumestrol | multiple interactions | ISO | NR2F6 (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of NR2F6 mRNA | CTD | PMID:19167446 | Nr2f6 | Rat | cyclosporin A | decreases expression | ISO | NR2F6 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of NR2F6 mRNA | CTD | PMID:20106945 | Nr2f6 | Rat | decabromodiphenyl ether | increases expression | EXP | | 6480464 | decabromobiphenyl ether results in increased expression of NR2F6 mRNA | CTD | PMID:23640034 and PMID:23914054 | Nr2f6 | Rat | diarsenic trioxide | decreases expression | ISO | NR2F6 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of NR2F6 mRNA | CTD | PMID:20458559 | Nr2f6 | Rat | Dibutyl phosphate | affects expression | ISO | NR2F6 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of NR2F6 mRNA | CTD | PMID:37042841 | Nr2f6 | Rat | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of NR2F6 mRNA | CTD | PMID:21266533 | Nr2f6 | Rat | dichloromethane | increases expression | ISO | Nr2f6 (Mus musculus) | 6480464 | Methylene Chloride results in increased expression of NR2F6 mRNA | CTD | PMID:28392392 | Nr2f6 | Rat | diclofenac | affects expression | ISO | NR2F6 (Homo sapiens) | 6480464 | Diclofenac affects the expression of NR2F6 mRNA | CTD | PMID:24752500 | Nr2f6 | Rat | diethylstilbestrol | increases expression | EXP | | 6480464 | Diethylstilbestrol results in increased expression of NR2F6 mRNA | CTD | PMID:17011747 | Nr2f6 | Rat | diquat | decreases expression | ISO | Nr2f6 (Mus musculus) | 6480464 | Diquat results in decreased expression of NR2F6 protein | CTD | PMID:36851058 | Nr2f6 | Rat | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of NR2F6 mRNA | CTD | PMID:29391264 | Nr2f6 | Rat | Enterolactone | multiple interactions | ISO | NR2F6 (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of NR2F6 mRNA | CTD | PMID:19167446 | Nr2f6 | Rat | epoxiconazole | increases expression | ISO | Nr2f6 (Mus musculus) | 6480464 | epoxiconazole results in increased expression of NR2F6 mRNA | CTD | PMID:35436446 | Nr2f6 | Rat | finasteride | increases expression | EXP | | 6480464 | Finasteride results in increased expression of NR2F6 mRNA | CTD | PMID:24136188 | Nr2f6 | Rat | folic acid | multiple interactions | ISO | Nr2f6 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of NR2F6 mRNA | CTD | PMID:22206623 | Nr2f6 | Rat | FR900359 | increases phosphorylation | ISO | NR2F6 (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of NR2F6 protein | CTD | PMID:37730182 | Nr2f6 | Rat | fulvestrant | increases expression | ISO | NR2F6 (Homo sapiens) | 6480464 | Fulvestrant results in increased expression of NR2F6 mRNA | CTD | PMID:31646340 | Nr2f6 | Rat | fulvestrant | multiple interactions | ISO | NR2F6 (Homo sapiens) | 6480464 | Estradiol inhibits the reaction [Fulvestrant results in increased expression of NR2F6 mRNA] and Fulvestrant inhibits the reaction [Estradiol results in increased expression of NR2F6 mRNA] | CTD | PMID:31646340 | Nr2f6 | Rat | gamma-hexachlorocyclohexane | affects expression | EXP | | 6480464 | Hexachlorocyclohexane affects the expression of NR2F6 mRNA | CTD | PMID:17785943 | Nr2f6 | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of NR2F6 mRNA | CTD | PMID:33387578 | Nr2f6 | Rat | hydrogen peroxide | decreases expression | ISO | NR2F6 (Homo sapiens) | 6480464 | Hydrogen Peroxide results in decreased expression of NR2F6 mRNA | CTD | PMID:12419474 | Nr2f6 | Rat | isoflurane | increases methylation | ISO | Nr2f6 (Mus musculus) | 6480464 | Isoflurane results in increased methylation of NR2F6 mRNA | CTD | PMID:35249202 | Nr2f6 | Rat | lead diacetate | decreases expression | ISO | Nr2f6 (Mus musculus) | 6480464 | lead acetate results in decreased expression of NR2F6 mRNA | CTD | PMID:25270620 | Nr2f6 | Rat | methapyrilene | decreases expression | EXP | | 6480464 | Methapyrilene results in decreased expression of NR2F6 mRNA | CTD | PMID:16393664 | Nr2f6 | Rat | methapyrilene | increases methylation | ISO | NR2F6 (Homo sapiens) | 6480464 | Methapyrilene results in increased methylation of NR2F6 intron | CTD | PMID:30157460 | Nr2f6 | Rat | methylmercury chloride | affects expression | ISO | Nr2f6 (Mus musculus) | 6480464 | methylmercuric chloride affects the expression of NR2F6 mRNA | CTD | PMID:21613230 | Nr2f6 | Rat | methylmercury(1+) | multiple interactions | EXP | | 6480464 | [Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in decreased expression of NR2F6 mRNA | CTD | PMID:17905399 | Nr2f6 | Rat | nickel dichloride | affects expression | EXP | | 6480464 | nickel chloride affects the expression of NR2F6 mRNA | CTD | PMID:22546817 | Nr2f6 | Rat | nickel sulfate | increases expression | ISO | NR2F6 (Homo sapiens) | 6480464 | nickel sulfate results in increased expression of NR2F6 mRNA | CTD | PMID:16780908 | Nr2f6 | Rat | p-tert-Amylphenol | increases expression | EXP | | 6480464 | 4-tert-octylphenol results in increased expression of NR2F6 mRNA | CTD | PMID:17011747 | Nr2f6 | Rat | paracetamol | decreases expression | ISO | NR2F6 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of NR2F6 mRNA | CTD | PMID:21420995 and PMID:29067470 | Nr2f6 | Rat | paraquat | increases expression | EXP | | 6480464 | Paraquat results in increased expression of NR2F6 mRNA | CTD | PMID:17077588 and PMID:18198484 | Nr2f6 | Rat | perfluorohexanesulfonic acid | decreases expression | ISO | Nr2f6 (Mus musculus) | 6480464 | perfluorohexanesulfonic acid results in decreased expression of NR2F6 mRNA | CTD | PMID:37995155 | Nr2f6 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Nr2f6 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of NR2F6 mRNA and [perfluorooctane sulfonic acid co-treated with Pectins] results in decreased expression of NR2F6 mRNA | CTD | PMID:36331819 | Nr2f6 | Rat | phenobarbital | affects expression | ISO | Nr2f6 (Mus musculus) | 6480464 | Phenobarbital affects the expression of NR2F6 mRNA | CTD | PMID:23091169 | Nr2f6 | Rat | pirinixic acid | decreases expression | ISO | Nr2f6 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of NR2F6 mRNA | CTD | PMID:18445702 | Nr2f6 | Rat | procymidone | increases expression | EXP | | 6480464 | procymidone results in increased expression of NR2F6 mRNA | CTD | PMID:15686871 | Nr2f6 | Rat | raloxifene | multiple interactions | ISO | NR2F6 (Homo sapiens) | 6480464 | [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NR2F6 mRNA | CTD | PMID:19059307 | Nr2f6 | Rat | raloxifene | affects expression | ISO | NR2F6 (Homo sapiens) | 6480464 | Raloxifene Hydrochloride affects the expression of NR2F6 mRNA | CTD | PMID:14699072 | Nr2f6 | Rat | sodium arsenite | increases expression | ISO | NR2F6 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of NR2F6 mRNA | CTD | PMID:12016162 and PMID:12760830 | Nr2f6 | Rat | sodium arsenite | decreases expression | ISO | Nr2f6 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of NR2F6 mRNA | CTD | PMID:16014739 and PMID:25270620 | Nr2f6 | Rat | tamoxifen | multiple interactions | ISO | NR2F6 (Homo sapiens) | 6480464 | [Tamoxifen co-treated with ESR2 protein] results in decreased expression of NR2F6 mRNA | CTD | PMID:19059307 | Nr2f6 | Rat | temozolomide | increases expression | ISO | NR2F6 (Homo sapiens) | 6480464 | Temozolomide results in increased expression of NR2F6 mRNA | CTD | PMID:31758290 | Nr2f6 | Rat | tert-butyl hydroperoxide | decreases expression | ISO | NR2F6 (Homo sapiens) | 6480464 | tert-Butylhydroperoxide results in decreased expression of NR2F6 mRNA | CTD | PMID:12419474 and PMID:15336504 | Nr2f6 | Rat | tetrachloroethene | decreases expression | ISO | Nr2f6 (Mus musculus) | 6480464 | Tetrachloroethylene results in decreased expression of NR2F6 mRNA | CTD | PMID:28973375 | Nr2f6 | Rat | tetrachloromethane | decreases expression | ISO | Nr2f6 (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of NR2F6 mRNA | CTD | PMID:31919559 | Nr2f6 | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of NR2F6 mRNA | CTD | PMID:34492290 | Nr2f6 | Rat | thiram | decreases expression | ISO | NR2F6 (Homo sapiens) | 6480464 | Thiram results in decreased expression of NR2F6 mRNA | CTD | PMID:38568856 | Nr2f6 | Rat | titanium dioxide | decreases methylation | ISO | Nr2f6 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of NR2F6 gene | CTD | PMID:35295148 | Nr2f6 | Rat | trichloroethene | multiple interactions | EXP | | 6480464 | [Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in decreased expression of NR2F6 mRNA | CTD | PMID:17905399 | Nr2f6 | Rat | triptonide | decreases expression | ISO | Nr2f6 (Mus musculus) | 6480464 | triptonide results in decreased expression of NR2F6 mRNA | CTD | PMID:33045310 | Nr2f6 | Rat | trovafloxacin | multiple interactions | ISO | Nr2f6 (Mus musculus) | 6480464 | [trovafloxacin co-treated with lipopolysaccharide and E coli O55-B5] results in decreased expression of NR2F6 mRNA | CTD | PMID:18930950 | Nr2f6 | Rat | urethane | decreases expression | ISO | NR2F6 (Homo sapiens) | 6480464 | Urethane results in decreased expression of NR2F6 mRNA | CTD | PMID:28818685 | Nr2f6 | Rat | vinclozolin | affects expression | EXP | | 6480464 | vinclozolin affects the expression of NR2F6 mRNA | CTD | PMID:19015723 | |