Obp1f (odorant binding protein I f) - Rat Genome Database

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Gene: Obp1f (odorant binding protein I f) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Obp1f
Name: odorant binding protein I f
RGD ID: 621639
Description: Enables odorant binding activity. Predicted to be involved in sensory perception of smell. Predicted to be located in extracellular region. Predicted to be active in extracellular space; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC103690319; OBP; Obp-1f; odorant-binding protein; odorant-binding protein 1F
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X45,833,861 - 45,839,070 (+)NCBIGRCr8GRCr8GRCr8
mRatBN7.2X41,955,618 - 41,960,681 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX41,955,618 - 41,960,681 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX43,258,991 - 43,264,064 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X46,726,331 - 46,731,404 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X44,391,061 - 44,396,138 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X83,847,944 - 83,864,150 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX45,282,187 - 45,284,341 (-)Ensemblrn6Rnor6.0
Rnor_5.0X83,742,999 - 83,746,062 (+)NCBIRnor_5.0Rnor_5.0rn5
Rnor_5.0X45,505,140 - 45,506,321 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X63,689,823 - 63,696,729 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX42,669,718 - 42,676,625 (-)NCBICelera
RGSC_v3.1X63,743,291 - 63,750,198 (-)NCBI
Cytogenetic MapXq21NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Ligand-binding properties and structural characterization of a novel rat odorant-binding protein variant. Briand L, etal., Eur J Biochem 2000 May;267(10):3079-89.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. Molecular cloning of odorant-binding protein: member of a ligand carrier family. Pevsner J, etal., Science 1988 Jul 15;241(4863):336-9.
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:15047593   PMID:16849331   PMID:17584948   PMID:19390145   PMID:19688223   PMID:20932975  


Genomics

Variants

.
Variants in Obp1f
17 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:128
Count of miRNA genes:111
Interacting mature miRNAs:115
Transcripts:ENSRNOT00000045436, ENSRNOT00000073734
Prediction methods:Microtar, Miranda, Pita, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
731181Uae27Urinary albumin excretion QTL 272.70.0059urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)X197044046970440Rat
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX45182909117740458Rat
631666Iddm5Insulin dependent diabetes mellitus QTL 5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X811148653111486Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X4493088389930883Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
3 9 45 64 49 34 5 34 2 120 30 28 53 53 15 2 2

Sequence


Ensembl Acc Id: ENSRNOT00000045436   ⟹   ENSRNOP00000039557
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX45,282,187 - 45,284,341 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000088538   ⟹   ENSRNOP00000071673
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX41,955,618 - 41,960,681 (+)Ensembl
Rnor_6.0 EnsemblX45,213,228 - 45,217,455 (+)Ensembl
RefSeq Acc Id: NM_138903   ⟹   NP_620258
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X45,834,006 - 45,839,069 (+)NCBI
mRatBN7.2X41,955,618 - 41,960,681 (+)NCBI
Rnor_6.0X83,847,944 - 83,864,150 (-)NCBI
Rnor_5.0X45,505,140 - 45,506,321 (-)NCBI
Rnor_5.0X83,742,999 - 83,746,062 (+)NCBI
RGSC_v3.4X63,689,823 - 63,696,729 (-)RGD
CeleraX42,669,718 - 42,676,625 (-)RGD
Sequence:
RefSeq Acc Id: XM_063279774   ⟹   XP_063135844
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X45,833,861 - 45,839,070 (+)NCBI
Protein Sequences
Protein RefSeqs NP_620258 (Get FASTA)   NCBI Sequence Viewer  
  XP_063135844 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein CAB61693 (Get FASTA)   NCBI Sequence Viewer  
  EDL96077 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000064887
GenBank Protein P08937 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_620258   ⟸   NM_138903
- Peptide Label: precursor
- UniProtKB: Q9QYU9 (UniProtKB/TrEMBL),   A6IPT6 (UniProtKB/TrEMBL),   A6IPT5 (UniProtKB/TrEMBL),   A0A0G2K124 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000039557   ⟸   ENSRNOT00000045436
Ensembl Acc Id: ENSRNOP00000071673   ⟸   ENSRNOT00000088538
RefSeq Acc Id: XP_063135844   ⟸   XM_063279774
- Peptide Label: isoform X1
Protein Domains
Lipocalin/cytosolic fatty-acid binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P08937-F1-model_v2 AlphaFold P08937 1-172 view protein structure
AF-Q9QYU9-F1-model_v2 AlphaFold Q9QYU9 1-173 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621639 AgrOrtholog
BioCyc Gene G2FUF-2409 BioCyc
Ensembl Genes ENSRNOG00000045757 Ensembl
  ENSRNOG00000058697 Ensembl
  ENSRNOG00000063224 Ensembl
  ENSRNOG00000086793 ENTREZGENE
Ensembl Transcript ENSRNOT00000073734 ENTREZGENE
Gene3D-CATH 2.40.128.20 UniProtKB/Swiss-Prot
InterPro Calycin UniProtKB/Swiss-Prot
  Lipocalin UniProtKB/Swiss-Prot
  Lipocalin_CS UniProtKB/Swiss-Prot
  Lipocln_cytosolic_FA-bd_dom UniProtKB/Swiss-Prot
  OBP-like UniProtKB/Swiss-Prot
KEGG Report rno:192267 UniProtKB/Swiss-Prot
NCBI Gene 192267 ENTREZGENE
PANTHER ODORANT-BINDING PROTEIN 1A-RELATED UniProtKB/Swiss-Prot
  PTHR11430 UniProtKB/Swiss-Prot
Pfam Lipocalin UniProtKB/Swiss-Prot
PhenoGen Obp1f PhenoGen
PRINTS ODORANTBNDNG UniProtKB/Swiss-Prot
PROSITE LIPOCALIN UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000045757 RatGTEx
  ENSRNOG00000058697 RatGTEx
  ENSRNOG00000063224 RatGTEx
  ENSRNOG00000086793 RatGTEx
Superfamily-SCOP SSF50814 UniProtKB/Swiss-Prot
UniProt A0A0G2K124 ENTREZGENE, UniProtKB/TrEMBL
  A6IPT5 ENTREZGENE, UniProtKB/TrEMBL
  A6IPT6 ENTREZGENE
  OBP_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q9QYU9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Obp1f  odorant binding protein I f  LOC103690319  odorant-binding protein  Data merged from RGD:9122946 737654 PROVISIONAL
2014-08-25 LOC103690319  odorant-binding protein      Symbol and Name status set to provisional 70820 PROVISIONAL
2004-02-11 Obp1f  odorant binding protein I f  Obp-1f  odorant-binding protein 1F  Symbol and Name updated to reflect Human and Mouse nomenclature 625702 APPROVED
2002-08-07 Obp-1f  odorant-binding protein 1F      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in nasal epithelium 633371
gene_protein 18,091-dalton protein 633371