Artn (artemin) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Artn (artemin) Rattus norvegicus
Analyze
Symbol: Artn
Name: artemin
RGD ID: 621427
Description: Predicted to enable growth factor activity. Involved in peripheral nervous system development. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Used to study peripheral nervous system disease. Biomarker of peripheral nervous system disease. Orthologous to human ARTN (artemin); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85136,750,188 - 136,755,645 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5136,750,188 - 136,753,457 (-)EnsemblGRCr8
mRatBN7.25131,458,596 - 131,470,193 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5131,464,756 - 131,468,025 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5134,169,882 - 134,173,127 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05135,924,501 - 135,927,746 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05135,946,923 - 135,950,168 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05136,759,717 - 136,765,036 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5136,759,717 - 136,762,986 (-)Ensemblrn6Rnor6.0
Rnor_5.05140,548,766 - 140,554,035 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45138,390,981 - 138,394,250 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5130,012,959 - 130,016,228 (-)NCBICelera
RGSC_v3.15138,396,703 - 138,397,079 (-)NCBI
Cytogenetic Map5q36NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Nerve growth factor and artemin are paracrine mediators of pancreatic neuropathy in pancreatic adenocarcinoma. Ceyhan GO, etal., Ann Surg. 2010 May;251(5):923-31.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. BDNF mRNA expression is significantly upregulated in vestibular schwannomas and correlates with proliferative activity. Kramer F, etal., J Neurooncol. 2010 May;98(1):31-9. doi: 10.1007/s11060-009-0063-6. Epub 2009 Nov 25.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
9. Expression of the GDNF family members and their receptors in the mature rat cochlea. Stover T, etal., Brain Res Mol Brain Res 2000 Mar 10;76(1):25-35.
10. Acetyl-l-carnitine increases artemin level and prevents neurotrophic factor alterations during neuropathy. Vivoli E, etal., Neuroscience. 2010 Jun 2;167(4):1168-74. Epub 2010 Mar 16.
11. Persistent restoration of sensory function by immediate or delayed systemic artemin after dorsal root injury. Wang R, etal., Nat Neurosci. 2008 Apr;11(4):488-96. Epub 2008 Mar 23.
12. Nan fang yi ke da xue xue bao = Journal of Southern Medical University Zhu DL, etal., Nan Fang Yi Ke Da Xue Xue Bao. 2009 Mar;29(3):428-32.
Additional References at PubMed
PMID:9883723   PMID:12160745   PMID:12477932   PMID:15204970   PMID:15489334   PMID:16325003   PMID:16781061   PMID:17322904   PMID:17337595   PMID:19845789   PMID:24886596   PMID:25889103  
PMID:25918373   PMID:28899786   PMID:29712778  


Genomics

Comparative Map Data
Artn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85136,750,188 - 136,755,645 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5136,750,188 - 136,753,457 (-)EnsemblGRCr8
mRatBN7.25131,458,596 - 131,470,193 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5131,464,756 - 131,468,025 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5134,169,882 - 134,173,127 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05135,924,501 - 135,927,746 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05135,946,923 - 135,950,168 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05136,759,717 - 136,765,036 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5136,759,717 - 136,762,986 (-)Ensemblrn6Rnor6.0
Rnor_5.05140,548,766 - 140,554,035 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45138,390,981 - 138,394,250 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5130,012,959 - 130,016,228 (-)NCBICelera
RGSC_v3.15138,396,703 - 138,397,079 (-)NCBI
Cytogenetic Map5q36NCBI
ARTN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38143,933,801 - 43,937,240 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl143,933,320 - 43,937,244 (+)Ensemblhg38GRCh38
GRCh37144,399,473 - 44,402,912 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36144,171,579 - 44,175,471 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34144,070,746 - 44,071,977NCBI
Celera142,682,525 - 42,686,445 (+)NCBICelera
Cytogenetic Map1p34.1NCBI
HuRef142,517,866 - 42,521,786 (+)NCBIHuRef
CHM1_1144,515,224 - 44,519,144 (+)NCBICHM1_1
T2T-CHM13v2.0143,802,329 - 43,808,317 (+)NCBIT2T-CHM13v2.0
Artn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394117,783,105 - 117,787,993 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4117,783,359 - 117,786,960 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm384117,925,908 - 117,930,795 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4117,926,162 - 117,929,763 (-)Ensemblmm10GRCm38
MGSCv374117,598,767 - 117,602,368 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv364117,424,094 - 117,427,695 (-)NCBIMGSCv36mm8
Celera4116,641,832 - 116,645,434 (-)NCBICelera
Cytogenetic Map4D1NCBI
cM Map453.83NCBI
Artn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555373,460,176 - 3,464,335 (+)Ensembl
ChiLan1.0NW_0049555373,460,176 - 3,464,335 (+)NCBIChiLan1.0ChiLan1.0
ARTN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21182,872,431 - 182,878,378 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11182,013,760 - 182,019,707 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0143,233,097 - 43,239,044 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1144,604,514 - 44,610,643 (+)NCBIPanPan1.1PanPan1.1panPan2
ARTN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha1516,435,953 - 16,442,427 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01516,469,613 - 16,476,086 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UMICH_Zoey_3.11516,268,455 - 16,274,928 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01516,340,604 - 16,343,946 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01516,410,202 - 16,416,677 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Artn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505859,423,684 - 59,434,755 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647425,252,684 - 25,253,810 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647425,252,510 - 25,254,221 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARTN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6167,357,662 - 167,361,221 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.16167,356,363 - 167,361,370 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26154,725,018 - 154,726,492 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ARTN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12088,869,463 - 88,874,036 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2088,869,941 - 88,871,049 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603328,051,970 - 28,057,269 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Artn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248923,214,012 - 3,218,699 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248923,213,203 - 3,218,699 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Artn
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1139,093,333 - 39,096,972 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Artn
22 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:44
Count of miRNA genes:40
Interacting mature miRNAs:40
Transcripts:ENSRNOT00000026852
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)5102105698152749382Rat
2303586Gluco52Glucose level QTL 522blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)5100826632145826632Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5130249266172190305Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)544924861153890773Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5116702075161702075Rat
1354583Despr3Despair related QTL34.980.0002locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)5132930505172190305Rat
1300122Wbc1White blood cell count QTL 12.75leukocyte quantity (VT:0000217)total white blood cell count (CMO:0000365)5130678987145274255Rat
7365049Bp359Blood pressure QTL 359arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5133308734140009902Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)599905133172190305Rat
70156Niddm30Non-insulin dependent diabetes mellitus QTL 303.98blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)5134369218156289444Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5133789363172190305Rat
1331803Rf32Renal function QTL 322.798kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)5134369199172190305Rat
7411582Foco3Food consumption QTL 37.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)592583776137583776Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)565089051166764498Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5136631198172190305Rat
7207486Bss109Bone structure and strength QTL 109femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)5112142946157142946Rat
7207481Bss106Bone structure and strength QTL 1067.9femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5112142946157142946Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5110770739155770739Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5133081618172190305Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
1581505Rf54Renal function QTL 54kidney physiology trait (VT:0002136)kidney 20-HETE level (CMO:0001854)5133270647172190305Rat
1549838Bss4Bone structure and strength QTL 49.2femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)5112142946157142946Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5133789363172190305Rat
7411564Bw135Body weight QTL 1350.001body mass (VT:0001259)body weight gain (CMO:0000420)592583776137583776Rat
1581510Cm54Cardiac mass QTL 543.40.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)5125969677172190305Rat
8657050Bw146Body weight QTL 14619.840.001body mass (VT:0001259)body weight gain (CMO:0000420)598972960143972960Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
7411601Foco12Food consumption QTL 1219.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)592583776137583776Rat
2303618Vencon1Ventilatory control QTL 13.8respiration trait (VT:0001943)oxygen consumption (CMO:0002169)5100826632145826632Rat
2317056Wbc3White blood cell count QTL 32.510.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)5111236572156236572Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5131708216172190305Rat
7394710Emca12Estrogen-induced mammary cancer QTL 12mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)594034903139034903Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5114131300159131300Rat
2293642Bss37Bone structure and strength QTL 374.640.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5125969677156302135Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)560601597137492949Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5116702075161702075Rat
7207488Bss110Bone structure and strength QTL 18.4femur strength trait (VT:0010010)femur stiffness (CMO:0001674)5112142946157142946Rat
7207491Bss112Bone structure and strength QTL 1127femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)5112142946157142946Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5116702075161702075Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)574335621156302135Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5116702075161702075Rat
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5114131300159131300Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5133081618172190305Rat
6903316Bw113Body weight QTL 11320.0103body mass (VT:0001259)body weight (CMO:0000012)592881678137881678Rat
1358187Emca1Estrogen-induced mammary cancer QTL 14.4mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)5104262817153890625Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 8 64 155 83 82 51 68 51 6 315 162 11 134 80 92 31 13 13

Sequence


Ensembl Acc Id: ENSRNOT00000026852   ⟹   ENSRNOP00000026852
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5136,750,188 - 136,753,457 (-)Ensembl
mRatBN7.2 Ensembl5131,464,756 - 131,468,025 (-)Ensembl
Rnor_6.0 Ensembl5136,759,717 - 136,762,986 (-)Ensembl
RefSeq Acc Id: NM_053397   ⟹   NP_445849
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85136,750,188 - 136,753,457 (-)NCBI
mRatBN7.25131,464,756 - 131,468,025 (-)NCBI
Rnor_6.05136,759,717 - 136,762,986 (-)NCBI
Rnor_5.05140,548,766 - 140,554,035 (-)NCBI
RGSC_v3.45138,390,981 - 138,394,250 (-)RGD
Celera5130,012,959 - 130,016,228 (-)RGD
Sequence:
RefSeq Acc Id: XM_039110297   ⟹   XP_038966225
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85136,750,188 - 136,755,645 (-)NCBI
mRatBN7.25131,458,596 - 131,470,193 (-)NCBI
RefSeq Acc Id: XM_039110299   ⟹   XP_038966227
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85136,750,188 - 136,755,645 (-)NCBI
mRatBN7.25131,458,596 - 131,470,193 (-)NCBI
RefSeq Acc Id: NP_445849   ⟸   NM_053397
- Peptide Label: precursor
- UniProtKB: Q9QZG3 (UniProtKB/Swiss-Prot),   Q810F7 (UniProtKB/Swiss-Prot),   Q810F6 (UniProtKB/Swiss-Prot),   Q6AYE8 (UniProtKB/Swiss-Prot),   A6JZG2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000026852   ⟸   ENSRNOT00000026852
RefSeq Acc Id: XP_038966227   ⟸   XM_039110299
- Peptide Label: isoform X1
- UniProtKB: Q9QZG3 (UniProtKB/Swiss-Prot),   Q810F7 (UniProtKB/Swiss-Prot),   Q810F6 (UniProtKB/Swiss-Prot),   Q6AYE8 (UniProtKB/Swiss-Prot),   A6JZG2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038966225   ⟸   XM_039110297
- Peptide Label: isoform X1
- UniProtKB: Q9QZG3 (UniProtKB/Swiss-Prot),   Q810F7 (UniProtKB/Swiss-Prot),   Q810F6 (UniProtKB/Swiss-Prot),   Q6AYE8 (UniProtKB/Swiss-Prot),   A6JZG2 (UniProtKB/TrEMBL)
Protein Domains
TGF-beta family profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AYE8-F1-model_v2 AlphaFold Q6AYE8 1-224 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693961
Promoter ID:EPDNEW_R4485
Type:multiple initiation site
Name:Artn_1
Description:artemin
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05136,763,030 - 136,763,090EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621427 AgrOrtholog
BioCyc Gene G2FUF-40175 BioCyc
Ensembl Genes ENSRNOG00000019842 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000026852 ENTREZGENE
  ENSRNOT00000026852.4 UniProtKB/Swiss-Prot
Gene3D-CATH 2.10.90.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7122331 IMAGE-MGC_LOAD
InterPro Cystine-knot_cytokine UniProtKB/Swiss-Prot
  GDNF_fam UniProtKB/Swiss-Prot
  TGF-b_C UniProtKB/Swiss-Prot
KEGG Report rno:362572 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94034 IMAGE-MGC_LOAD
NCBI Gene Artn ENTREZGENE
PANTHER ARTEMIN UniProtKB/Swiss-Prot
  PTHR12173 UniProtKB/Swiss-Prot
Pfam TGF_beta UniProtKB/Swiss-Prot
PhenoGen Artn PhenoGen
PROSITE TGF_BETA_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000019842 RatGTEx
Superfamily-SCOP SSF57501 UniProtKB/Swiss-Prot
UniProt A6JZG2 ENTREZGENE, UniProtKB/TrEMBL
  ARTN_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q810F6 ENTREZGENE
  Q810F7 ENTREZGENE
  Q9QZG3 ENTREZGENE
UniProt Secondary Q810F6 UniProtKB/Swiss-Prot
  Q810F7 UniProtKB/Swiss-Prot
  Q9QZG3 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-01-20 Artn  artemin      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Artn  artemin      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in cochlea and substantia nigra 631959
gene_product member of the glial cell line-derived neurotrophic factor subgroup of the TGF-beta growth factor superfamily 631959