Srp54a (signal recognition particle 54A) - Rat Genome Database

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Gene: Srp54a (signal recognition particle 54A) Rattus norvegicus
Analyze
Symbol: Srp54a
Name: signal recognition particle 54A
RGD ID: 621390
Description: Predicted to enable several functions, including 7S RNA binding activity; endoplasmic reticulum signal peptide binding activity; and guanyl ribonucleotide binding activity. Predicted to contribute to GTPase activity. Predicted to be involved in several processes, including SRP-dependent cotranslational protein targeting to membrane; exocrine pancreas development; and neutrophil chemotaxis. Predicted to be located in cytoplasm and nucleus. Predicted to be part of signal recognition particle, endoplasmic reticulum targeting. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in severe congenital neutropenia 8. Orthologous to human SRP54 (signal recognition particle 54); INTERACTS WITH 2,6-dinitrotoluene; 6-propyl-2-thiouracil; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: signal recognition particle 54; signal recognition particle 54 kDa; signal recognition particle 54kDa; signal recognition particle subunit SRP54; Srp54
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8678,322,308 - 78,362,017 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl678,322,721 - 78,362,031 (+)EnsemblGRCr8
mRatBN7.2672,587,584 - 72,626,878 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl672,587,605 - 72,625,189 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx673,010,076 - 73,047,802 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0673,316,425 - 73,354,151 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0672,745,035 - 72,782,580 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0675,996,629 - 76,035,768 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl675,996,643 - 76,034,083 (+)Ensemblrn6Rnor6.0
Rnor_5.0685,532,350 - 85,572,100 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4675,446,838 - 75,494,001 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera671,428,873 - 71,466,500 (+)NCBICelera
RGSC_v3.1675,474,626 - 75,478,796 (+)NCBI
Cytogenetic Map6q23NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
7. Modulation of the signal recognition particle 54-kDa subunit (SRP54) in rat preosteoblasts by the extracellular matrix. Traianedes K, etal., J Biol Chem 1995 Sep 8;270(36):20891-4.
Additional References at PubMed
PMID:8247130   PMID:8521805   PMID:8622769   PMID:9511762   PMID:10618370   PMID:12477932   PMID:15489334   PMID:16469117   PMID:18089836   PMID:22658674   PMID:28972538   PMID:31505169  


Genomics

Comparative Map Data
Srp54a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8678,322,308 - 78,362,017 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl678,322,721 - 78,362,031 (+)EnsemblGRCr8
mRatBN7.2672,587,584 - 72,626,878 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl672,587,605 - 72,625,189 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx673,010,076 - 73,047,802 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0673,316,425 - 73,354,151 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0672,745,035 - 72,782,580 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0675,996,629 - 76,035,768 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl675,996,643 - 76,034,083 (+)Ensemblrn6Rnor6.0
Rnor_5.0685,532,350 - 85,572,100 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4675,446,838 - 75,494,001 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera671,428,873 - 71,466,500 (+)NCBICelera
RGSC_v3.1675,474,626 - 75,478,796 (+)NCBI
Cytogenetic Map6q23NCBI
SRP54
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381434,982,992 - 35,029,567 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1434,981,957 - 35,029,686 (+)Ensemblhg38GRCh38
GRCh371435,452,198 - 35,498,773 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361434,521,982 - 34,568,519 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341434,521,981 - 34,568,517NCBI
Celera1415,315,912 - 15,362,600 (+)NCBICelera
Cytogenetic Map14q13.2NCBI
HuRef1415,564,659 - 15,611,702 (+)NCBIHuRef
CHM1_11435,450,690 - 35,497,725 (+)NCBICHM1_1
T2T-CHM13v2.01429,181,721 - 29,228,319 (+)NCBIT2T-CHM13v2.0
Srp54a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391255,127,318 - 55,162,152 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1255,127,047 - 55,162,152 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381255,080,476 - 55,115,367 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1255,080,262 - 55,115,367 (+)Ensemblmm10GRCm38
MGSCv371256,181,483 - 56,216,354 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361255,998,696 - 56,031,814 (+)NCBIMGSCv36mm8
Celera1256,371,141 - 56,408,843 (+)NCBICelera
Cytogenetic Map12C1NCBI
cM Map1223.86NCBI
Srp54
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540925,977,226 - 26,016,351 (-)Ensembl
ChiLan1.0NW_00495540925,977,226 - 26,016,351 (-)NCBIChiLan1.0ChiLan1.0
LOC100987236
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21536,293,771 - 36,393,170 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11435,510,292 - 35,609,673 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01415,733,446 - 15,779,987 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11433,920,330 - 33,966,023 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1433,920,287 - 34,017,151 (+)EnsemblpanPan2panpan1.1
SRP54
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1813,800,275 - 13,837,799 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl813,677,760 - 13,837,722 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha813,597,521 - 13,634,635 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0813,907,202 - 13,944,631 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl813,907,474 - 13,944,627 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1813,608,264 - 13,646,077 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0813,673,490 - 13,710,632 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0813,962,922 - 13,999,855 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
LOC101965130
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864045,677,956 - 45,741,100 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364949,183,632 - 9,222,855 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0 EnsemblNW_0049364949,227,321 - 9,246,955 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364949,183,620 - 9,220,510 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SRP54
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl764,829,228 - 64,877,195 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1764,829,625 - 64,877,574 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2769,658,033 - 69,706,782 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103228813
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12411,802,671 - 11,846,534 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2411,859,688 - 11,899,545 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
ChlSab1.1 Ensembl2411,812,672 - 11,846,675 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666053764,178 - 808,147 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Srp54
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248381,697,863 - 1,747,136 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248381,697,863 - 1,747,115 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Srp54a
348 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:786
Count of miRNA genes:310
Interacting mature miRNAs:397
Transcripts:ENSRNOT00000052076
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590290Uminl2Urine mineral level QTL 23.960.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)64451097489510974Rat
2293088Iddm28Insulin dependent diabetes mellitus QTL 285.21blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)668767270135411972Rat
4889933Bss88Bone structure and strength QTL 883.8tibia size trait (VT:0100001)tibia total bone volume (CMO:0001724)65368492198684921Rat
634307Bp141Blood pressure QTL 1414arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)64095756485957564Rat
1331743Uae28Urinary albumin excretion QTL 284.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)64515378690153786Rat
5684992Bmd83Bone mineral density QTL 824.8tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)65368492198684921Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)671278722116278722Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)664367996109367996Rat
1558641Cm47Cardiac mass QTL 472.90.001heart mass (VT:0007028)heart wet weight (CMO:0000069)66345744194939581Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)646050607116278722Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)64604735391047353Rat
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62661831486868070Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)620859430113082285Rat
9590140Scort4Serum corticosterone level QTL 414.490.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)64451097489510974Rat
2301964Bp323Blood pressure QTL 3234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6186868070Rat
9590306Scort18Serum corticosterone level QTL 182.880.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)64451097489510974Rat
1578665Bss16Bone structure and strength QTL 164.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)63332884178328841Rat
2293841Kiddil4Kidney dilation QTL 44.4kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62661831486868070Rat
4889848Pur25Proteinuria QTL 25140.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)66303731995934232Rat
1578668Bmd14Bone mineral density QTL 143.8femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)63332884178328841Rat
6893340Cm77Cardiac mass QTL 770.260.57heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)63902865986867923Rat
5684963Bss99Bone structure and strength QTL 993.1tibia area (VT:1000281)tibia area measurement (CMO:0001382)65368492198684921Rat
1576302Schws4Schwannoma susceptibility QTL 40.0078nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)678204640123204640Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)676937178121937178Rat
1300143Rf14Renal function QTL 142.92renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)64016318385163183Rat
6893332Cm74Cardiac mass QTL 740.40.64heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)66345744194939581Rat

Markers in Region
D6Rat22  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8678,328,752 - 78,328,841 (+)Marker Load Pipeline
mRatBN7.2672,593,596 - 72,593,685 (+)MAPPERmRatBN7.2
Rnor_6.0676,002,643 - 76,002,731NCBIRnor6.0
Rnor_5.0685,538,356 - 85,538,444UniSTSRnor5.0
RGSC_v3.4675,462,022 - 75,462,111RGDRGSC3.4
RGSC_v3.4675,462,023 - 75,462,111UniSTSRGSC3.4
Celera671,434,873 - 71,434,961UniSTS
RGSC_v3.1675,465,149 - 75,465,237RGD
RH 2.0 Map6698.7RGD
SHRSP x BN Map647.8099RGD
FHH x ACI Map656.9999RGD
Cytogenetic Map6q23UniSTS
D6Got311  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2672,604,632 - 72,604,860 (+)MAPPERmRatBN7.2
Rnor_6.0676,013,618 - 76,013,845NCBIRnor6.0
Rnor_5.0685,549,608 - 85,549,835UniSTSRnor5.0
RGSC_v3.4675,473,358 - 75,473,585UniSTSRGSC3.4
Celera671,445,833 - 71,446,060UniSTS
Cytogenetic Map6q23UniSTS
RH128735  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2672,624,967 - 72,625,149 (+)MAPPERmRatBN7.2
Rnor_6.0676,033,858 - 76,034,039NCBIRnor6.0
Rnor_5.0685,570,203 - 85,570,384UniSTSRnor5.0
RGSC_v3.4675,493,773 - 75,493,954UniSTSRGSC3.4
Celera671,466,272 - 71,466,453UniSTS
Cytogenetic Map6q23UniSTS
RH144431  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2672,626,550 - 72,626,805 (+)MAPPERmRatBN7.2
Rnor_6.0676,035,441 - 76,035,695NCBIRnor6.0
Rnor_5.0685,571,786 - 85,572,040UniSTSRnor5.0
RGSC_v3.4675,495,356 - 75,495,610UniSTSRGSC3.4
Celera671,467,855 - 71,468,109UniSTS
Cytogenetic Map6q23UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000052076   ⟹   ENSRNOP00000048945
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl678,322,721 - 78,360,344 (+)Ensembl
mRatBN7.2 Ensembl672,587,605 - 72,625,189 (+)Ensembl
Rnor_6.0 Ensembl675,996,643 - 76,034,083 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000098782   ⟹   ENSRNOP00000085749
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl678,322,742 - 78,362,031 (+)Ensembl
mRatBN7.2 Ensembl672,587,630 - 72,625,181 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000131173   ⟹   ENSRNOP00000104350
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl678,322,742 - 78,362,031 (+)Ensembl
RefSeq Acc Id: NM_053871   ⟹   NP_446323
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8678,322,753 - 78,360,348 (+)NCBI
mRatBN7.2672,587,597 - 72,625,196 (+)NCBI
Rnor_6.0675,996,643 - 76,034,086 (+)NCBI
Rnor_5.0685,532,350 - 85,572,100 (+)NCBI
RGSC_v3.4675,446,838 - 75,494,001 (+)RGD
Celera671,428,873 - 71,466,500 (+)RGD
Sequence:
RefSeq Acc Id: XM_006240097   ⟹   XP_006240159
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8678,322,308 - 78,362,017 (+)NCBI
mRatBN7.2672,587,622 - 72,625,196 (+)NCBI
Rnor_6.0675,996,629 - 76,035,768 (+)NCBI
Rnor_5.0685,532,350 - 85,572,100 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_446323 (Get FASTA)   NCBI Sequence Viewer  
  XP_006240159 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB17124 (Get FASTA)   NCBI Sequence Viewer  
  AAH79117 (Get FASTA)   NCBI Sequence Viewer  
  EDM03421 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000048945.3
  ENSRNOP00000085749
  ENSRNOP00000104350
GenBank Protein Q6AYB5 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_446323   ⟸   NM_053871
- UniProtKB: Q6AYB5 (UniProtKB/Swiss-Prot),   A0A8I6A4J0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240159   ⟸   XM_006240097
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A4J0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000048945   ⟸   ENSRNOT00000052076
Ensembl Acc Id: ENSRNOP00000085749   ⟸   ENSRNOT00000098782
Ensembl Acc Id: ENSRNOP00000104350   ⟸   ENSRNOT00000131173
Protein Domains
SRP54-type proteins GTP-binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AYB5-F1-model_v2 AlphaFold Q6AYB5 1-504 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694602
Promoter ID:EPDNEW_R5126
Type:initiation region
Name:Srp54a_1
Description:signal recognition particle 54A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0675,996,654 - 75,996,714EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621390 AgrOrtholog
BioCyc Gene G2FUF-37492 BioCyc
Ensembl Genes ENSRNOG00000032776 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000052076.5 UniProtKB/Swiss-Prot
  ENSRNOT00000098782 ENTREZGENE
  ENSRNOT00000131173 ENTREZGENE
Gene3D-CATH 1.10.260.30 UniProtKB/Swiss-Prot
  1.20.120.140 UniProtKB/Swiss-Prot
  3.40.50.300 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7126297 IMAGE-MGC_LOAD
InterPro AAA+_ATPase UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
  Signal_recog_part_SRP54_M_sf UniProtKB/Swiss-Prot
  Signal_recog_particl_SRP54_hlx UniProtKB/Swiss-Prot
  Signal_recog_particle_SRP54_M UniProtKB/Swiss-Prot
  SRP54 UniProtKB/Swiss-Prot
  SRP54_euk UniProtKB/Swiss-Prot
  SRP54_GTPase_dom UniProtKB/Swiss-Prot
  SRP54_N_sf UniProtKB/Swiss-Prot
KEGG Report rno:116650 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94117 IMAGE-MGC_LOAD
NCBI Gene 116650 ENTREZGENE
PANTHER PTHR11564 UniProtKB/Swiss-Prot
  SIGNAL RECOGNITION PARTICLE 54 KDA PROTEIN UniProtKB/Swiss-Prot
Pfam SRP54 UniProtKB/Swiss-Prot
  SRP54_N UniProtKB/Swiss-Prot
  SRP_SPB UniProtKB/Swiss-Prot
PhenoGen Srp54a PhenoGen
PROSITE SRP54 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000032776 RatGTEx
SMART AAA UniProtKB/Swiss-Prot
  SRP54 UniProtKB/Swiss-Prot
  SRP54_N UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47446 UniProtKB/Swiss-Prot
  SSF52540 UniProtKB/Swiss-Prot
UniProt A0A8I6A4J0 ENTREZGENE, UniProtKB/TrEMBL
  Q6AYB5 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-11-19 Srp54a  signal recognition particle 54A  Srp54a  signal recognition particle 54kDa  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-11-11 Srp54a  signal recognition particle 54kDa  Srp54  signal recognition particle 54A  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-02-03 Srp54  signal recognition particle 54A  Srp54a  signal recognition particle 54a  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-05-15 Srp54a  signal recognition particle 54a  Srp54  signal recognition particle 54  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-08 Srp54  signal recognition particle 54    signal recognition particle 54 kDa  Name updated 1299863 APPROVED
2002-08-07 Srp54  signal recognition particle 54 kDa      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression mRNA expression increases in preosteoblastic cells subcultured on collagen compared with subculture on plastic only 634092