Stag3 (STAG3 cohesin complex component) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Stag3 (STAG3 cohesin complex component) Rattus norvegicus
Analyze
Symbol: Stag3
Name: STAG3 cohesin complex component (Ensembl:stromal antigen 3)
RGD ID: 621333
Description: Predicted to enable chromatin binding activity. Predicted to be involved in establishment of meiotic sister chromatid cohesion. Predicted to act upstream of or within homologous chromosome pairing at meiosis and protein localization to chromosome. Predicted to be located in chromatin; male germ cell nucleus; and nuclear lumen. Predicted to be part of meiotic cohesin complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in primary ovarian insufficiency 8 and spermatogenic failure 61. Orthologous to human STAG3 (STAG3 cohesin complex component); INTERACTS WITH 17beta-estradiol; 6-propyl-2-thiouracil; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: cohesin subunit SA-3; cohesin subunit SA-3-like; LOC102553065; SCC3 homolog 3; stromal antigen 3; stromalin 3; stromalin-3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81222,398,291 - 22,428,548 (+)NCBIGRCr8
mRatBN7.21217,284,677 - 17,314,936 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1217,284,794 - 17,314,935 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1218,251,836 - 18,281,954 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01218,875,558 - 18,905,676 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01217,928,975 - 17,959,093 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01219,599,741 - 19,630,775 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1219,599,834 - 19,630,780 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01221,656,406 - 21,686,863 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41217,865,273 - 17,896,993 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11217,854,794 - 17,886,514 (+)NCBI
Celera1219,209,251 - 19,239,357 (+)NCBICelera
Cytogenetic Map12q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Evaluation of the Stag3 gene and the synaptonemal complex in a rat model (as/as) for male infertility. Bayes M, etal., Mol Reprod Dev 2001 Nov;60(3):414-7.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10698974   PMID:15870106   PMID:17696610   PMID:21242291   PMID:21527826   PMID:22164254   PMID:22664934   PMID:22711701   PMID:24797475  


Genomics

Comparative Map Data
Stag3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81222,398,291 - 22,428,548 (+)NCBIGRCr8
mRatBN7.21217,284,677 - 17,314,936 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1217,284,794 - 17,314,935 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1218,251,836 - 18,281,954 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01218,875,558 - 18,905,676 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01217,928,975 - 17,959,093 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01219,599,741 - 19,630,775 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1219,599,834 - 19,630,780 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01221,656,406 - 21,686,863 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41217,865,273 - 17,896,993 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11217,854,794 - 17,886,514 (+)NCBI
Celera1219,209,251 - 19,239,357 (+)NCBICelera
Cytogenetic Map12q11NCBI
STAG3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387100,177,724 - 100,219,334 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7100,177,563 - 100,214,387 (+)EnsemblGRCh38hg38GRCh38
GRCh37799,775,347 - 99,812,010 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36799,613,474 - 99,649,946 (+)NCBINCBI36Build 36hg18NCBI36
Build 34799,420,188 - 99,456,661NCBI
Celera794,510,888 - 94,547,361 (+)NCBICelera
Cytogenetic Map7q22.1NCBI
HuRef794,410,283 - 94,446,767 (+)NCBIHuRef
CHM1_1799,705,616 - 99,742,079 (+)NCBICHM1_1
T2T-CHM13v2.07101,417,534 - 101,459,147 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2799,135,619 - 99,172,096 (+)NCBI
Stag3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395138,270,757 - 138,310,659 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5138,278,502 - 138,310,655 (+)EnsemblGRCm39 Ensembl
GRCm385138,272,514 - 138,312,397 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5138,280,240 - 138,312,393 (+)EnsemblGRCm38mm10GRCm38
MGSCv375138,721,737 - 138,753,621 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365138,510,339 - 138,542,181 (+)NCBIMGSCv36mm8
Celera5135,263,360 - 135,295,714 (+)NCBICelera
Cytogenetic Map5G2NCBI
cM Map577.01NCBI
Stag3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955573602,016 - 630,936 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955573602,635 - 631,775 (-)NCBIChiLan1.0ChiLan1.0
STAG3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26118,096,086 - 118,133,316 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17166,360,718 - 166,397,948 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0792,215,064 - 92,249,202 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17105,645,413 - 105,682,220 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7105,648,425 - 105,681,850 (+)Ensemblpanpan1.1panPan2
STAG3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.169,326,402 - 9,354,049 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl69,326,448 - 9,353,204 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha611,030,377 - 11,058,041 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.069,260,281 - 9,287,741 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl69,260,338 - 9,286,897 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.169,112,910 - 9,140,199 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.069,091,601 - 9,119,271 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.069,272,833 - 9,300,317 (-)NCBIUU_Cfam_GSD_1.0
Stag3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344133,578,049 - 133,603,974 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936543432,552 - 458,112 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936543430,804 - 458,112 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STAG3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl38,175,915 - 8,211,889 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.138,175,908 - 8,211,898 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.237,310,188 - 7,346,525 (-)NCBISscrofa10.2Sscrofa10.2susScr3
STAG3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12812,853,456 - 12,893,098 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2812,853,404 - 12,891,638 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660703,388,692 - 3,427,657 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Stag3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474016,707,999 - 16,732,537 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474016,706,695 - 16,734,142 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Stag3
62 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:41
Count of miRNA genes:36
Interacting mature miRNAs:38
Transcripts:ENSRNOT00000042006
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61443Btemp2Thermal response to stress QTL 23.30.000094body temperature trait (VT:0005535)core body temperature (CMO:0001036)121502518320794014Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)12960327746669029Rat
61331Eau2Experimental allergic uveoretinitis QTL 20.0005uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)12852542328064601Rat
2293684Bmd26Bone mineral density QTL 264.40.0002femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)121587265332974238Rat
6893681Bw109Body weight QTL 1092.30.004body mass (VT:0001259)body weight (CMO:0000012)12123297788Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)12719673046669029Rat
1598855Bp294Blood pressure QTL 2943.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12134851688Rat
1600391Edcs2Endometrial carcinoma susceptibility QTL23.50.01uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)12683319017870186Rat
10755457Coatc14Coat color QTL 140.01759coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)12122591684Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121107382545055165Rat
8694179Bw150Body weight QTL 1502.90.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
7411545Bw128Body weight QTL 1285.20.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)6556449546669029Rat
1300157Rf21Renal function QTL 214.4renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)12931821632103380Rat
737979Pia22Pristane induced arthritis QTL 2253.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12144465750Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121047413746669029Rat
7411660Foco28Food consumption QTL 2810.90.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
1331755Bp219Blood pressure QTL 2193.041arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121107382528064557Rat
2312418Kidm41Kidney mass QTL 413.70.0001kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)12119611090Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
1549912Bp268Blood pressure QTL 268arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)101318273646669029Rat
2302060Pia37Pristane induced arthritis QTL 376.10.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)121319815746669029Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121281238546669029Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449846669029Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)12610757946669029Rat
1581516Cm56Cardiac mass QTL 564.20.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)12129333307Rat
9590086Insglur6Insulin/glucose ratio QTL 618.970.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)12142110980Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
1549902Bp269Blood pressure QTL 269arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)121318273646669029Rat
61404Bw120Body weight QTL 1205.1body mass (VT:0001259)body mass index (BMI) (CMO:0000105)121235161946669029Rat
1331786Kidm11Kidney mass QTL 113.571kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)121107382524234895Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121047413746669029Rat
634351Apr5Acute phase response QTL 56.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)12144503507Rat
634350Apr4Acute phase response QTL 46orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)12117200546172005Rat
61416Pia4Pristane induced arthritis QTL 48.4joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)121363552330827399Rat
7204484Bp358Blood pressure QTL 3580.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121300829619212979Rat
7387292Kidm42Kidney mass QTL 423.030.0004kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)12136247923Rat
61421Cia12Collagen induced arthritis QTL 124.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121363552335682913Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121281238546669029Rat
7411586Foco5Food consumption QTL 55.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12142450532Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
2302042Pia38Pristane induced arthritis QTL 383.50.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)12144503507Rat
7411595Foco9Food consumption QTL 940.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
2293086Iddm30Insulin dependent diabetes mellitus QTL 303.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)12844949028302290Rat
631543Bp83Blood pressure QTL 835.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)121555082638478808Rat

Markers in Region
D12Rat29  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21217,310,678 - 17,310,845 (+)MAPPERmRatBN7.2
Rnor_6.01219,626,515 - 19,626,681NCBIRnor6.0
Rnor_5.01221,682,606 - 21,682,772UniSTSRnor5.0
RGSC_v3.41217,892,735 - 17,892,902RGDRGSC3.4
RGSC_v3.41217,892,736 - 17,892,902UniSTSRGSC3.4
RGSC_v3.11217,882,258 - 17,882,424RGD
Celera1219,235,112 - 19,235,266UniSTS
RH 3.4 Map12250.2UniSTS
RH 3.4 Map12250.2RGD
RH 2.0 Map12181.0RGD
SHRSP x BN Map1221.58RGD
Cytogenetic Map12q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 7 33 111 57 57 26 22 26 6 151 75 92 35 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000042006   ⟹   ENSRNOP00000041918
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1217,284,794 - 17,314,935 (+)Ensembl
Rnor_6.0 Ensembl1219,599,960 - 19,630,771 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000092039   ⟹   ENSRNOP00000072692
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1219,599,834 - 19,630,780 (+)Ensembl
RefSeq Acc Id: NM_053730   ⟹   NP_446182
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81222,398,408 - 22,428,548 (+)NCBI
mRatBN7.21217,284,794 - 17,314,936 (+)NCBI
Rnor_6.01219,599,960 - 19,630,772 (+)NCBI
Rnor_5.01221,656,406 - 21,686,863 (+)NCBI
RGSC_v3.41217,865,273 - 17,896,993 (+)RGD
Celera1219,209,251 - 19,239,357 (+)RGD
Sequence:
RefSeq Acc Id: XM_006249020   ⟹   XP_006249082
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81222,398,291 - 22,428,548 (+)NCBI
mRatBN7.21217,284,677 - 17,314,936 (+)NCBI
Rnor_6.01219,599,863 - 19,630,775 (+)NCBI
Rnor_5.01221,656,406 - 21,686,863 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039089015   ⟹   XP_038944943
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81222,398,297 - 22,428,548 (+)NCBI
mRatBN7.21217,284,677 - 17,314,936 (+)NCBI
RefSeq Acc Id: XM_039089016   ⟹   XP_038944944
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81222,398,754 - 22,428,548 (+)NCBI
mRatBN7.21217,285,149 - 17,314,936 (+)NCBI
RefSeq Acc Id: XM_039089017   ⟹   XP_038944945
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81222,398,499 - 22,428,548 (+)NCBI
mRatBN7.21217,284,979 - 17,314,936 (+)NCBI
RefSeq Acc Id: XM_039089018   ⟹   XP_038944946
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81222,398,291 - 22,428,548 (+)NCBI
mRatBN7.21217,284,677 - 17,314,936 (+)NCBI
RefSeq Acc Id: XM_063270988   ⟹   XP_063127058
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81222,398,300 - 22,428,548 (+)NCBI
RefSeq Acc Id: NP_446182   ⟸   NM_053730
- UniProtKB: Q99M76 (UniProtKB/Swiss-Prot),   A6KSU8 (UniProtKB/TrEMBL),   A6KSU9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006249082   ⟸   XM_006249020
- Peptide Label: isoform X1
- UniProtKB: Q99M76 (UniProtKB/Swiss-Prot),   A6KSU8 (UniProtKB/TrEMBL),   A6KSU9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000072692   ⟸   ENSRNOT00000092039
Ensembl Acc Id: ENSRNOP00000041918   ⟸   ENSRNOT00000042006
RefSeq Acc Id: XP_038944946   ⟸   XM_039089018
- Peptide Label: isoform X2
- UniProtKB: A6KSU9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944943   ⟸   XM_039089015
- Peptide Label: isoform X1
- UniProtKB: Q99M76 (UniProtKB/Swiss-Prot),   A6KSU8 (UniProtKB/TrEMBL),   A6KSU9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944945   ⟸   XM_039089017
- Peptide Label: isoform X1
- UniProtKB: Q99M76 (UniProtKB/Swiss-Prot),   A6KSU8 (UniProtKB/TrEMBL),   A6KSU9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944944   ⟸   XM_039089016
- Peptide Label: isoform X1
- UniProtKB: Q99M76 (UniProtKB/Swiss-Prot),   A6KSU8 (UniProtKB/TrEMBL),   A6KSU9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063127058   ⟸   XM_063270988
- Peptide Label: isoform X2
Protein Domains
SCD

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q99M76-F1-model_v2 AlphaFold Q99M76 1-1256 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698504
Promoter ID:EPDNEW_R9027
Type:multiple initiation site
Name:Stag3_1
Description:stromal antigen 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01219,599,847 - 19,599,907EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621333 AgrOrtholog
BioCyc Gene G2FUF-19773 BioCyc
Ensembl Genes ENSRNOG00000001360 Ensembl, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000042006.5 UniProtKB/Swiss-Prot
Gene3D-CATH 1.25.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cohesin_Scc3/SA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SCD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STAG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:114522 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 114522 ENTREZGENE
PANTHER COHESIN SUBUNIT SA-3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11199 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam SCD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STAG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Stag3 PhenoGen
PROSITE SCD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000001360 RatGTEx
Superfamily-SCOP ARM repeat UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
UniProt A6KSU8 ENTREZGENE, UniProtKB/TrEMBL
  A6KSU9 ENTREZGENE, UniProtKB/TrEMBL
  Q99M76 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-05-05 Stag3  STAG3 cohesin complex component  Stag3  stromal antigen 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2021-03-09 Stag3  stromal antigen 3  LOC102553065  cohesin subunit SA-3-like  Data merged from RGD:7729409 737654 PROVISIONAL
2013-12-18 LOC102553065  cohesin subunit SA-3-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2004-02-26 Stag3  stromal antigen 3      Symbol and Name status set to approved 625702 APPROVED
2002-08-07 Stag3  stromal antigen 3      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_domains contains a polymorphic hexanucleotide repeat doamin 727325
gene_homology aa sequence shares 93% identity with mouse Stag3, and 77% with human STAG3 727325
gene_product member of the stromalin protein family 727325
gene_protein predicted protein contains 1256 aa residues 727325