Il11ra1 (interleukin 11 receptor subunit alpha 1) - Rat Genome Database

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Gene: Il11ra1 (interleukin 11 receptor subunit alpha 1) Rattus norvegicus
Analyze
Symbol: Il11ra1
Name: interleukin 11 receptor subunit alpha 1
RGD ID: 621332
Description: Predicted to enable interleukin-11 binding activity and interleukin-11 receptor activity. Involved in embryo implantation. Predicted to be located in extracellular region and membrane. Predicted to be part of receptor complex. Predicted to be active in external side of plasma membrane. Orthologous to human IL11RA (interleukin 11 receptor subunit alpha); PARTICIPATES IN cytokine mediated signaling pathway; Jak-Stat signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: IL-11 receptor subunit alpha; IL-11R subunit alpha; IL-11R-alpha; IL-11RA; interleukin 11 receptor, alpha chain 1; interleukin-11 receptor alpha chain; interleukin-11 receptor subunit alpha
RGD Orthologs
Human
Mouse
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8561,727,650 - 61,737,265 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl561,727,931 - 61,737,264 (+)EnsemblGRCr8
mRatBN7.2556,931,824 - 56,941,408 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl556,935,516 - 56,941,408 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx558,908,620 - 58,915,700 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0560,727,450 - 60,734,530 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0560,713,513 - 60,720,605 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0558,149,150 - 58,159,072 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl558,151,985 - 58,159,072 (+)Ensemblrn6Rnor6.0
Rnor_5.0562,673,838 - 62,683,436 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4559,192,698 - 59,199,783 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera555,526,482 - 55,533,561 (+)NCBICelera
RGSC_v3.1559,192,876 - 59,199,962 (+)NCBI
Cytogenetic Map5q22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2-methylcholine  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
Azoxymethane  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
cadmium dichloride  (ISO)
cannabidiol  (ISO)
capsaicin  (EXP)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlordecone  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
cobalt dichloride  (EXP)
copper atom  (EXP)
copper(0)  (EXP)
cyclosporin A  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
dibutyl phthalate  (EXP)
diuron  (EXP)
ethanol  (ISO)
ferulic acid  (ISO)
finasteride  (EXP)
graphite  (EXP)
GSK-J4  (ISO)
imiquimod  (ISO)
indometacin  (ISO)
methidathion  (ISO)
methimazole  (EXP)
methylmercury chloride  (ISO)
nickel atom  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
propiconazole  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
sulindac  (EXP)
sunitinib  (ISO)
temozolomide  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
toluene 2,4-diisocyanate  (ISO)
Tributyltin oxide  (ISO)
trimellitic anhydride  (ISO)
triptonide  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Cloning of rat interleukin 11 and interleukin 11 receptor alpha chain and analysis of their expression in rat uterus in the peri-implantation period. Li R, etal., Reproduction 2001 Oct;122(4):593-600.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:7957045   PMID:9500603   PMID:9679067   PMID:14701802   PMID:15489334   PMID:15499555   PMID:21741611   PMID:36521373  


Genomics

Comparative Map Data
Il11ra1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8561,727,650 - 61,737,265 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl561,727,931 - 61,737,264 (+)EnsemblGRCr8
mRatBN7.2556,931,824 - 56,941,408 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl556,935,516 - 56,941,408 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx558,908,620 - 58,915,700 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0560,727,450 - 60,734,530 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0560,713,513 - 60,720,605 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0558,149,150 - 58,159,072 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl558,151,985 - 58,159,072 (+)Ensemblrn6Rnor6.0
Rnor_5.0562,673,838 - 62,683,436 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4559,192,698 - 59,199,783 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera555,526,482 - 55,533,561 (+)NCBICelera
RGSC_v3.1559,192,876 - 59,199,962 (+)NCBI
Cytogenetic Map5q22NCBI
IL11RA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38934,652,185 - 34,661,902 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl934,651,582 - 34,661,902 (+)Ensemblhg38GRCh38
GRCh37934,652,182 - 34,661,899 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36934,643,932 - 34,651,884 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34934,643,931 - 34,650,815NCBI
Celera934,583,653 - 34,593,355 (+)NCBICelera
Cytogenetic Map9p13.3NCBI
HuRef934,606,462 - 34,616,181 (+)NCBIHuRef
CHM1_1934,651,965 - 34,661,682 (+)NCBICHM1_1
T2T-CHM13v2.0934,670,713 - 34,680,432 (+)NCBIT2T-CHM13v2.0
Il11ra1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39441,760,443 - 41,769,473 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl441,699,989 - 41,769,474 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38441,760,443 - 41,769,473 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl441,699,989 - 41,769,474 (+)Ensemblmm10GRCm38
MGSCv37441,707,316 - 41,716,346 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36441,950,869 - 41,957,984 (+)NCBIMGSCv36mm8
Celera441,421,225 - 41,430,277 (+)NCBICelera
Cytogenetic Map4A5NCBI
cM Map421.94NCBI
Il11ra
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554721,475,178 - 1,482,206 (-)Ensembl
ChiLan1.0NW_0049554721,474,802 - 1,485,352 (-)NCBIChiLan1.0ChiLan1.0
IL11RA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11151,324,915 - 51,341,981 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1149,953,267 - 49,970,134 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01152,265,652 - 52,282,519 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1152,268,766 - 52,275,323 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11150,928,355 - 50,945,221 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01150,796,497 - 50,813,366 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01151,561,269 - 51,578,140 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Il11ra
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947166,184,831 - 166,211,247 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365242,735,507 - 2,742,660 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365242,732,477 - 2,743,044 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IL11RA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1032,139,063 - 32,146,138 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11032,138,984 - 32,149,315 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21036,278,889 - 36,289,165 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IL11RA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11245,959,370 - 45,970,563 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1245,955,863 - 45,969,310 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603843,076,251 - 43,087,084 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Il11ra
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473639,046,176 - 39,055,306 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473639,043,972 - 39,055,689 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Il11ra
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v113,784,829 - 3,794,462 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Il11ra1
52 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:40
Count of miRNA genes:36
Interacting mature miRNAs:38
Transcripts:ENSRNOT00000020885
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)53275164977751649Rat
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53801167083011670Rat
1300115Hrtrt7Heart rate QTL 72.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)55266537294894052Rat
6907115Mcs29Mammary carcinoma susceptibility QTL 29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)53800433183004331Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)544924861153890773Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)52367149379046465Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)538207390136631402Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51757663362576633Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)548523123134369373Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53801167083011670Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53801167083011670Rat
1331782Rf36Renal function QTL 363.296kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)539019942102105896Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)53331167378311673Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)53275164977751649Rat
1641922Alcrsp8Alcohol response QTL 8alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)51748608062486080Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)53998594884985948Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)5692228281330203Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53331167378311673Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)53952692484526924Rat
1331773Scl26Serum cholesterol level QTL 263.065blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)54852312391770353Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)560601597137492949Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906491770353Rat
61359EaexExperimental allergic encephalomyelitis QTL x3nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)560511627105511627Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5706553574335773Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)536460764136631402Rat
1641903Alcrsp3Alcohol response QTL 3response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)51748608062486080Rat
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906487027358Rat
8552954Pigfal14Plasma insulin-like growth factor 1 level QTL 149blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)52602321171023211Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)556546393101546393Rat
1600358Mamtr5Mammary tumor resistance QTL 5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)52367149368671493Rat

Markers in Region
RH141539  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2556,941,240 - 56,941,390 (+)MAPPERmRatBN7.2
Rnor_6.0558,158,905 - 58,159,054NCBIRnor6.0
Rnor_5.0562,683,271 - 62,683,420UniSTSRnor5.0
RGSC_v3.4559,199,618 - 59,199,767UniSTSRGSC3.4
Celera555,533,396 - 55,533,545UniSTS
Cytogenetic Map5q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 162 91 90 59 66 59 6 330 166 11 141 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000020885   ⟹   ENSRNOP00000020885
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl561,727,931 - 61,737,264 (+)Ensembl
mRatBN7.2 Ensembl556,935,516 - 56,941,408 (+)Ensembl
Rnor_6.0 Ensembl558,151,985 - 58,159,072 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000117668   ⟹   ENSRNOP00000094379
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl556,935,516 - 56,941,392 (+)Ensembl
RefSeq Acc Id: NM_139116   ⟹   NP_620816
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8561,730,180 - 61,737,265 (+)NCBI
mRatBN7.2556,934,321 - 56,941,406 (+)NCBI
Rnor_6.0558,151,985 - 58,159,070 (+)NCBI
Rnor_5.0562,673,838 - 62,683,436 (+)NCBI
RGSC_v3.4559,192,698 - 59,199,783 (+)RGD
Celera555,526,482 - 55,533,561 (+)RGD
Sequence:
RefSeq Acc Id: XM_006238023   ⟹   XP_006238085
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8561,727,650 - 61,737,265 (+)NCBI
mRatBN7.2556,931,829 - 56,941,408 (+)NCBI
Rnor_6.0558,149,158 - 58,159,072 (+)NCBI
Rnor_5.0562,673,838 - 62,683,436 (+)NCBI
Sequence:
RefSeq Acc Id: NP_620816   ⟸   NM_139116
- Peptide Label: precursor
- UniProtKB: Q99MF4 (UniProtKB/Swiss-Prot),   A6IIX5 (UniProtKB/TrEMBL),   A0A8I6ARG9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006238085   ⟸   XM_006238023
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000020885   ⟸   ENSRNOT00000020885
Ensembl Acc Id: ENSRNOP00000094379   ⟸   ENSRNOT00000117668
Protein Domains
Fibronectin type-III   Ig-like   Ig-like C2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q99MF4-F1-model_v2 AlphaFold Q99MF4 1-431 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693659
Promoter ID:EPDNEW_R4184
Type:multiple initiation site
Name:Il11ra1_1
Description:interleukin 11 receptor subunit alpha 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0558,151,966 - 58,152,026EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621332 AgrOrtholog
BioCyc Gene G2FUF-41541 BioCyc
Ensembl Genes ENSRNOG00000015068 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000020885 ENTREZGENE
  ENSRNOT00000020885.6 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7105297 IMAGE-MGC_LOAD
InterPro FN3_dom UniProtKB/Swiss-Prot
  FN3_sf UniProtKB/Swiss-Prot
  Hematopoietin_rcpt_L_F3_CS UniProtKB/Swiss-Prot
  Ig-like_dom UniProtKB/Swiss-Prot
  Ig-like_dom_sf UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Ig_sub UniProtKB/Swiss-Prot
  IL11/IL27_subunit_beta UniProtKB/Swiss-Prot
KEGG Report rno:245983 UniProtKB/Swiss-Prot
MGC_CLONE MGC:91472 IMAGE-MGC_LOAD
NCBI Gene 245983 ENTREZGENE
PANTHER INTERLEUKIN-27 SUBUNIT BETA UniProtKB/Swiss-Prot
  INTERLEUKIN-27 SUBUNIT BETA UniProtKB/Swiss-Prot
PhenoGen Il11ra1 PhenoGen
PROSITE FN3 UniProtKB/Swiss-Prot
  HEMATOPO_REC_L_F3 UniProtKB/Swiss-Prot
  IG_LIKE UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000015068 RatGTEx
SMART FN3 UniProtKB/Swiss-Prot
  SM00409 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot
  SSF49265 UniProtKB/Swiss-Prot
UniProt A0A8I6ARG9 ENTREZGENE
  A6IIX5 ENTREZGENE, UniProtKB/TrEMBL
  I11RA_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-07-13 Il11ra1  interleukin 11 receptor subunit alpha 1  Il11ra1  interleukin 11 receptor, alpha chain 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Il11ra1  interleukin 11 receptor, alpha chain 1      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Il11ra1  interleukin 11 receptor, alpha chain 1      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expression is high in the uterine primary decidual zone at the time of the attachment reaction 1302225