Arf4 (ARF GTPase 4) - Rat Genome Database

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Gene: Arf4 (ARF GTPase 4) Rattus norvegicus
Analyze
Symbol: Arf4
Name: ARF GTPase 4 (Ensembl:ADP-ribosylation factor 4)
RGD ID: 621275
Description: Predicted to enable several functions, including GTP binding activity; NAD+-protein-arginine ADP-ribosyltransferase activity; and epidermal growth factor receptor binding activity. Involved in epidermal growth factor receptor signaling pathway and response to axon injury. Predicted to be located in several cellular components, including Golgi membrane; dendritic spine; and ruffle membrane. Predicted to be active in cytoplasm; glutamatergic synapse; and plasma membrane. Orthologous to human ARF4 (ARF GTPase 4); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ADP-ribosylation factor 4
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8161,903,238 - 1,920,012 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl161,903,371 - 1,920,011 (+)EnsemblGRCr8
mRatBN7.2161,896,692 - 1,913,267 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl161,896,546 - 1,913,261 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx161,903,319 - 1,919,895 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0163,049,015 - 3,065,591 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0161,909,772 - 1,926,348 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0162,338,333 - 2,354,909 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl162,338,333 - 2,354,909 (+)Ensemblrn6Rnor6.0
Rnor_5.0162,313,358 - 2,330,255 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4161,955,745 - 1,972,321 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera161,865,523 - 1,882,099 (+)NCBICelera
RGSC_v3.1161,955,744 - 1,972,321 (+)NCBI
Cytogenetic Map16p16NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dimethoxyphenol  (ISO)
2-nitrotoluene  (EXP)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP)
ammonium chloride  (EXP)
Aroclor 1254  (ISO)
azoxystrobin  (ISO)
beta-lapachone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
bleomycin A5  (ISO)
bromochloroacetic acid  (EXP)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloropicrin  (ISO)
chlorpyrifos  (ISO)
clobetasol  (ISO)
cocaine  (EXP)
Cuprizon  (EXP)
cyclosporin A  (ISO)
DDE  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP,ISO)
dichlorine  (EXP)
dioxygen  (ISO)
diuron  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
eugenol  (EXP)
fipronil  (EXP)
flutamide  (EXP)
folic acid  (ISO)
furfural  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
glyphosate  (ISO)
indirubin  (ISO)
inulin  (ISO)
isoprenaline  (ISO)
ivermectin  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
methylmercury chloride  (ISO)
ochratoxin A  (ISO)
okadaic acid  (ISO)
ozone  (EXP)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
picoxystrobin  (ISO)
propiconazole  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
Soman  (EXP)
tamoxifen  (ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (EXP,ISO)
thiram  (ISO)
titanium dioxide  (ISO)
tolcapone  (EXP)
trichloroethene  (EXP)
triphenyl phosphate  (ISO)
triptonide  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IEA,ISO)
cytosol  (IEA,ISO)
dendritic spine  (IEA,ISO)
glutamatergic synapse  (IEA,ISO)
Golgi apparatus  (IEA,ISO)
Golgi membrane  (IEA,ISO,ISS)
membrane  (IEA)
plasma membrane  (IBA,IEA,ISO)
ruffle membrane  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. P-CIP1, a novel protein that interacts with the cytosolic domain of peptidylglycine alpha-amidating monooxygenase, is associated with endosomes. Chen L, etal., J Biol Chem 1998 Dec 11;273(50):33524-32.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. ADP-ribosylation factor 4 small GTPase mediates epidermal growth factor receptor-dependent phospholipase D2 activation. Kim SW, etal., J Biol Chem 2003 Jan 24;278(4):2661-8.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Regulation of ADP-ribosylation factor (ARF) expression. Cross-species conservation of the developmental and tissue-specific alternative polyadenylation of ARF 4 mRNA. Mishima K, etal., J Biol Chem 1992 Nov 25;267(33):24109-16.
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. Interspecies relationships among ADP-ribosylation factors (ARFs): evidence of evolutionary pressure to maintain individual identities. Price SR, etal., Mol Cell Biochem 1996 Jun 7;159(1):15-23.
8. GOA pipeline RGD automated data pipeline
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Comprehensive gene review and curation RGD comprehensive gene curation
11. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
12. Localization of mRNAs for six ARFs (ADP-ribosylation factors) in the brain of developing and adult rats and changes in the expression in the hypoglossal nucleus after its axotomy. Suzuki I, etal., Brain Res Mol Brain Res. 2001 Mar 31;88(1-2):124-34.
Additional References at PubMed
PMID:1899243   PMID:8947846   PMID:15489334   PMID:19041174   PMID:19946888   PMID:20458337   PMID:20921225   PMID:21700703   PMID:22004728   PMID:23050017   PMID:23376485   PMID:23979707  
PMID:24586199   PMID:24768165   PMID:29476059   PMID:33450132  


Genomics

Comparative Map Data
Arf4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8161,903,238 - 1,920,012 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl161,903,371 - 1,920,011 (+)EnsemblGRCr8
mRatBN7.2161,896,692 - 1,913,267 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl161,896,546 - 1,913,261 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx161,903,319 - 1,919,895 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0163,049,015 - 3,065,591 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0161,909,772 - 1,926,348 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0162,338,333 - 2,354,909 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl162,338,333 - 2,354,909 (+)Ensemblrn6Rnor6.0
Rnor_5.0162,313,358 - 2,330,255 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4161,955,745 - 1,972,321 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera161,865,523 - 1,882,099 (+)NCBICelera
RGSC_v3.1161,955,744 - 1,972,321 (+)NCBI
Cytogenetic Map16p16NCBI
ARF4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38357,571,363 - 57,597,344 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl357,571,363 - 57,598,220 (-)Ensemblhg38GRCh38
GRCh37357,557,090 - 57,583,071 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36357,532,130 - 57,558,118 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34357,532,129 - 57,558,118NCBI
Celera357,570,930 - 57,583,662 (-)NCBICelera
Cytogenetic Map3p14.3NCBI
HuRef357,654,526 - 57,680,689 (-)NCBIHuRef
CHM1_1357,507,192 - 57,533,313 (-)NCBICHM1_1
T2T-CHM13v2.0357,611,733 - 57,637,720 (-)NCBIT2T-CHM13v2.0
Arf4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391426,359,289 - 26,377,997 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1426,359,229 - 26,386,239 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381426,638,134 - 26,656,842 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1426,638,074 - 26,665,084 (+)Ensemblmm10GRCm38
MGSCv371427,457,683 - 27,476,744 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361425,471,381 - 25,490,442 (+)NCBIMGSCv36mm8
Celera1422,881,059 - 22,899,926 (+)NCBICelera
Cytogenetic Map14A3NCBI
cM Map1416.09NCBI
Arf4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554307,289,255 - 7,319,083 (-)Ensembl
ChiLan1.0NW_0049554307,288,386 - 7,319,449 (-)NCBIChiLan1.0ChiLan1.0
ARF4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2257,539,666 - 57,566,805 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1357,544,439 - 57,571,074 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0357,504,701 - 57,530,545 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1358,710,897 - 58,736,315 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl358,710,897 - 58,736,816 (-)EnsemblpanPan2panpan1.1
ARF4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12032,849,725 - 32,871,127 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2032,849,757 - 32,870,721 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2032,777,874 - 32,799,283 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02033,122,306 - 33,143,713 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2033,122,415 - 33,159,515 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12032,578,184 - 32,599,566 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02032,936,246 - 32,957,656 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02033,106,867 - 33,128,487 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Arf4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118174,768,725 - 174,788,135 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364737,907,320 - 7,926,668 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364737,907,277 - 7,926,816 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARF4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1339,409,376 - 39,430,129 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11339,410,094 - 39,430,177 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21343,338,149 - 43,361,729 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ARF4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12218,879,064 - 18,904,234 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2218,877,715 - 18,903,891 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666041147,967,881 - 147,993,267 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arf4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624821346,579 - 362,021 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Arf4
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1132,441,614 - 2,458,284 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Arf4
60 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:492
Count of miRNA genes:236
Interacting mature miRNAs:284
Transcripts:ENSRNOT00000017692
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)1638712345387123Rat
1549842Bp248Blood pressure QTL 2480.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1638712345387123Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16133425095Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16139568015Rat
2303566Bw90Body weight QTL 902body mass (VT:0001259)body weight (CMO:0000012)16139568015Rat
631524Bp75Blood pressure QTL 750.05arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)161177108157035Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1683908666195506Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)1683908666195506Rat
12903955Kidm69Kidney mass QTL 690.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)168392304234212Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1683908666195506Rat
634355Rends4Renal damage susceptibility QTL 40.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)16126734272Rat
61405Niddm6Non-insulin dependent diabetes mellitus QTL 63.660.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)16126734272Rat
2293343Glom16Glomerulus QTL 167.4kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1683908652786090Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1683908666195506Rat
631830Alc7Alcohol consumption QTL 72.9consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16126734272Rat

Markers in Region
RH125729  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2161,912,966 - 1,913,213 (+)MAPPERmRatBN7.2
Rnor_6.0162,354,609 - 2,354,855NCBIRnor6.0
Rnor_5.0162,329,955 - 2,330,201UniSTSRnor5.0
RGSC_v3.4161,972,021 - 1,972,267UniSTSRGSC3.4
Celera161,881,799 - 1,882,045UniSTS
Cytogenetic Map16p16UniSTS
RH129316  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2161,912,978 - 1,913,143 (+)MAPPERmRatBN7.2
Rnor_6.0162,354,621 - 2,354,785NCBIRnor6.0
Rnor_5.0162,329,967 - 2,330,131UniSTSRnor5.0
RGSC_v3.4161,972,033 - 1,972,197UniSTSRGSC3.4
Celera161,881,811 - 1,881,975UniSTS
RH 3.4 Map1616.3UniSTS
Cytogenetic Map16p16UniSTS
RH129652  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2161,913,052 - 1,913,245 (+)MAPPERmRatBN7.2
Rnor_6.0162,354,695 - 2,354,887NCBIRnor6.0
Rnor_5.0162,330,041 - 2,330,233UniSTSRnor5.0
RGSC_v3.4161,972,107 - 1,972,299UniSTSRGSC3.4
Celera161,881,885 - 1,882,077UniSTS
RH 3.4 Map1616.3UniSTS
Cytogenetic Map16p16UniSTS
AW533731  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2161,896,445 - 1,896,636 (+)MAPPERmRatBN7.2
Rnor_6.0162,338,087 - 2,338,277NCBIRnor6.0
Rnor_5.0162,313,112 - 2,313,302UniSTSRnor5.0
RGSC_v3.4161,955,499 - 1,955,689UniSTSRGSC3.4
Celera161,865,277 - 1,865,467UniSTS
Cytogenetic Map16p16UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000017692   ⟹   ENSRNOP00000017692
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl161,903,371 - 1,920,011 (+)Ensembl
mRatBN7.2 Ensembl161,896,626 - 1,913,261 (+)Ensembl
Rnor_6.0 Ensembl162,338,333 - 2,354,909 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000104253   ⟹   ENSRNOP00000077700
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl161,896,546 - 1,911,447 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000117367   ⟹   ENSRNOP00000094601
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl161,903,652 - 1,920,011 (+)Ensembl
mRatBN7.2 Ensembl161,896,908 - 1,913,261 (+)Ensembl
RefSeq Acc Id: NM_024151   ⟹   NP_077065
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8161,903,436 - 1,920,012 (+)NCBI
mRatBN7.2161,896,692 - 1,913,267 (+)NCBI
Rnor_6.0162,338,333 - 2,354,909 (+)NCBI
Rnor_5.0162,313,358 - 2,330,255 (+)NCBI
RGSC_v3.4161,955,745 - 1,972,321 (+)RGD
Celera161,865,523 - 1,882,099 (+)RGD
Sequence:
RefSeq Acc Id: XM_063275756   ⟹   XP_063131826
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8161,903,238 - 1,919,475 (+)NCBI
Protein Sequences
Protein RefSeqs NP_077065 (Get FASTA)   NCBI Sequence Viewer  
  XP_063131826 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA40688 (Get FASTA)   NCBI Sequence Viewer  
  AAH63167 (Get FASTA)   NCBI Sequence Viewer  
  EDL75072 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000017692
  ENSRNOP00000017692.2
GenBank Protein P61751 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_077065   ⟸   NM_024151
- UniProtKB: P36403 (UniProtKB/Swiss-Prot),   P61751 (UniProtKB/Swiss-Prot),   A6KMJ6 (UniProtKB/TrEMBL),   A0A8I6AL60 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000017692   ⟸   ENSRNOT00000017692
Ensembl Acc Id: ENSRNOP00000094601   ⟸   ENSRNOT00000117367
Ensembl Acc Id: ENSRNOP00000077700   ⟸   ENSRNOT00000104253
RefSeq Acc Id: XP_063131826   ⟸   XM_063275756
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZJK0 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P61751-F1-model_v2 AlphaFold P61751 1-180 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699895
Promoter ID:EPDNEW_R10419
Type:initiation region
Name:Arf4_1
Description:ADP-ribosylation factor 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0162,338,372 - 2,338,432EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621275 AgrOrtholog
BioCyc Gene G2FUF-12252 BioCyc
Ensembl Genes ENSRNOG00000012623 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000017692 ENTREZGENE
  ENSRNOT00000017692.6 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:6921397 IMAGE-MGC_LOAD
InterPro Arf1_5_like UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
  Small_GTP-bd_dom UniProtKB/Swiss-Prot
  Small_GTPase_ARF UniProtKB/Swiss-Prot
  Small_GTPase_ARF/SAR UniProtKB/Swiss-Prot
KEGG Report rno:79120 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72808 IMAGE-MGC_LOAD
NCBI Gene 79120 ENTREZGENE
PANTHER PTHR11711 UniProtKB/Swiss-Prot
Pfam Arf UniProtKB/Swiss-Prot
PharmGKB ARF4 RGD
PhenoGen Arf4 PhenoGen
PRINTS SAR1GTPBP UniProtKB/Swiss-Prot
PROSITE ARF UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000012623 RatGTEx
SMART ARF UniProtKB/Swiss-Prot
  RAB UniProtKB/Swiss-Prot
  SAR UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot
UniProt A0A8I5ZJK0 ENTREZGENE
  A0A8I6AL60 ENTREZGENE, UniProtKB/TrEMBL
  A6KMJ6 ENTREZGENE, UniProtKB/TrEMBL
  ARF4_RAT UniProtKB/Swiss-Prot
  P36403 ENTREZGENE
  P61751 ENTREZGENE
UniProt Secondary P36403 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-11-07 Arf4  ARF GTPase 4  Arf4  ADP-ribosylation factor 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Arf4  ADP-ribosylation factor 4      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Arf4  ADP-ribosylation factor 4      Symbol and Name status set to provisional 70820 PROVISIONAL