Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Arf3 | Rat | (S)-nicotine | multiple interactions | ISO | Arf3 (Mus musculus) | 6480464 | [Nicotine co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of ARF3 mRNA; Nicotine inhibits the reaction more ... | CTD | PMID:20230807 | Arf3 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Arf3 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in decreased expression of ARF3 mRNA | CTD | PMID:22206623 | Arf3 | Rat | 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | decreases expression | ISO | Arf3 (Mus musculus) | 6480464 | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of ARF3 mRNA | CTD | PMID:20230807 | Arf3 | Rat | 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | multiple interactions | ISO | Arf3 (Mus musculus) | 6480464 | [Nicotine co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of ARF3 mRNA; Nicotine inhibits the reaction more ... | CTD | PMID:20230807 | Arf3 | Rat | 17alpha-ethynylestradiol | decreases expression | ISO | ARF3 (Homo sapiens) | 6480464 | Ethinyl Estradiol results in decreased expression of ARF3 mRNA | CTD | PMID:18936297 | Arf3 | Rat | 17beta-estradiol | increases expression | ISO | Arf3 (Mus musculus) | 6480464 | Estradiol results in increased expression of ARF3 mRNA | CTD | PMID:39298647 | Arf3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Arf3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ARF3 mRNA | CTD | PMID:21354282 | Arf3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of ARF3 mRNA | CTD | PMID:34747641 | Arf3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Arf3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of ARF3 mRNA | CTD | PMID:21570461 | Arf3 | Rat | 2-ethoxyethanol | increases expression | EXP | | 6480464 | 2-ethoxyethanol results in increased expression of ARF3 mRNA | CTD | PMID:19643169 | Arf3 | Rat | 2-methoxyethanol | increases expression | EXP | | 6480464 | methyl cellosolve results in increased expression of ARF3 mRNA | CTD | PMID:19643169 | Arf3 | Rat | 3,3',5,5'-tetrabromobisphenol A | increases expression | EXP | | 6480464 | tetrabromobisphenol A results in increased expression of ARF3 mRNA | CTD | PMID:27914987 | Arf3 | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | ARF3 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... | CTD | PMID:28628672 | Arf3 | Rat | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of more ... | CTD | PMID:36041667 | Arf3 | Rat | 4-vinylcyclohexene dioxide | affects expression | ISO | Arf3 (Mus musculus) | 6480464 | 4-vinyl-1-cyclohexene dioxide affects the expression of ARF3 mRNA | CTD | PMID:20829426 | Arf3 | Rat | 5-fluorouracil | affects response to substance | ISO | ARF3 (Homo sapiens) | 6480464 | ARF3 protein affects the susceptibility to Fluorouracil | CTD | PMID:15548681 | Arf3 | Rat | 7,12-dimethyltetraphene | decreases expression | ISO | Arf3 (Mus musculus) | 6480464 | 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of ARF3 protein | CTD | PMID:39910959 | Arf3 | Rat | acrylamide | decreases expression | ISO | ARF3 (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of ARF3 mRNA | CTD | PMID:32763439 | Arf3 | Rat | aflatoxin B1 | decreases expression | ISO | Arf3 (Mus musculus) | 6480464 | Aflatoxin B1 results in decreased expression of ARF3 mRNA | CTD | PMID:19770486 | Arf3 | Rat | Ampullosporin | multiple interactions | EXP | | 6480464 | [ampullosporin co-treated with Ketamine] results in decreased expression of ARF3 mRNA | CTD | PMID:16635253 | Arf3 | Rat | antirheumatic drug | decreases expression | ISO | ARF3 (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of ARF3 mRNA | CTD | PMID:24449571 | Arf3 | Rat | arsane | affects methylation | ISO | ARF3 (Homo sapiens) | 6480464 | Arsenic affects the methylation of ARF3 gene | CTD | PMID:25304211 | Arf3 | Rat | arsenic atom | affects methylation | ISO | ARF3 (Homo sapiens) | 6480464 | Arsenic affects the methylation of ARF3 gene | CTD | PMID:25304211 | Arf3 | Rat | arsenite(3-) | multiple interactions | ISO | ARF3 (Homo sapiens) | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to ARF3 protein] | CTD | PMID:32406909 | Arf3 | Rat | benzo[a]pyrene | affects methylation | ISO | ARF3 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of ARF3 5' UTR | CTD | PMID:27901495 | Arf3 | Rat | bis(2-ethylhexyl) phthalate | increases expression | ISO | Arf3 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in increased expression of ARF3 mRNA | CTD | PMID:34319233 | Arf3 | Rat | bisphenol A | increases expression | ISO | ARF3 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of ARF3 mRNA; bisphenol A results in increased expression more ... | CTD | PMID:20678512|PMID:34186270 | Arf3 | Rat | bisphenol A | decreases expression | ISO | Arf3 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of ARF3 protein | CTD | PMID:35999755 | Arf3 | Rat | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of more ... | CTD | PMID:36041667 | Arf3 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of ARF3 mRNA | CTD | PMID:25181051|PMID:41034487 | Arf3 | Rat | bisphenol AF | increases expression | ISO | ARF3 (Homo sapiens) | 6480464 | bisphenol AF results in increased expression of ARF3 protein | CTD | PMID:34186270 | Arf3 | Rat | bisphenol F | multiple interactions | ISO | ARF3 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... | CTD | PMID:28628672 | Arf3 | Rat | bisphenol F | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of more ... | CTD | PMID:36041667 | Arf3 | Rat | butanal | decreases expression | ISO | ARF3 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of ARF3 mRNA | CTD | PMID:26079696 | Arf3 | Rat | carbon nanotube | decreases expression | ISO | Arf3 (Mus musculus) | 6480464 | Nanotubes, Carbon results in decreased expression of ARF3 mRNA | CTD | PMID:25554681 | Arf3 | Rat | clobetasol | increases expression | ISO | Arf3 (Mus musculus) | 6480464 | Clobetasol results in increased expression of ARF3 mRNA | CTD | PMID:27462272 | Arf3 | Rat | cobalt dichloride | decreases expression | ISO | ARF3 (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of ARF3 mRNA | CTD | PMID:19376846 | Arf3 | Rat | crocidolite asbestos | decreases expression | ISO | Arf3 (Mus musculus) | 6480464 | Asbestos, Crocidolite results in decreased expression of ARF3 mRNA | CTD | PMID:29279043 | Arf3 | Rat | crocidolite asbestos | affects expression | ISO | Arf3 (Mus musculus) | 6480464 | Asbestos, Crocidolite affects the expression of ARF3 mRNA | CTD | PMID:19446018 | Arf3 | Rat | CU-O LINKAGE | decreases expression | ISO | ARF3 (Homo sapiens) | 6480464 | cupric oxide results in decreased expression of ARF3 protein | CTD | PMID:25470785 | Arf3 | Rat | dexamethasone | multiple interactions | ISO | ARF3 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... | CTD | PMID:28628672 | Arf3 | Rat | dextran sulfate | decreases expression | ISO | Arf3 (Mus musculus) | 6480464 | Dextran Sulfate results in decreased expression of ARF3 protein | CTD | PMID:35999755 | Arf3 | Rat | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of ARF3 mRNA | CTD | PMID:17379624 | Arf3 | Rat | dichlorine | multiple interactions | EXP | | 6480464 | [Ozone co-treated with Chlorine] results in decreased expression of ARF3 mRNA | CTD | PMID:18636392 | Arf3 | Rat | doxorubicin | decreases expression | ISO | ARF3 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of ARF3 mRNA | CTD | PMID:29803840 | Arf3 | Rat | ethanol | affects splicing | ISO | Arf3 (Mus musculus) | 6480464 | Ethanol affects the splicing of ARF3 mRNA | CTD | PMID:30319688 | Arf3 | Rat | FR900359 | increases phosphorylation | ISO | ARF3 (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of ARF3 protein | CTD | PMID:37730182 | Arf3 | Rat | gamma-tocopherol | increases expression | ISO | Arf3 (Mus musculus) | 6480464 | Tocopherols results in increased expression of ARF3 mRNA | CTD | PMID:17654050 | Arf3 | Rat | glyphosate | decreases expression | ISO | Arf3 (Mus musculus) | 6480464 | Glyphosate results in decreased expression of ARF3 protein | CTD | PMID:37208198 | Arf3 | Rat | haloperidol | decreases expression | EXP | | 6480464 | Haloperidol results in decreased expression of ARF3 mRNA | CTD | PMID:15860345 | Arf3 | Rat | hydrogen sulfide | decreases expression | ISO | Arf3 (Mus musculus) | 6480464 | Hydrogen Sulfide results in decreased expression of ARF3 protein | CTD | PMID:29932956 | Arf3 | Rat | indometacin | multiple interactions | ISO | ARF3 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... | CTD | PMID:28628672 | Arf3 | Rat | ketamine | multiple interactions | EXP | | 6480464 | [ampullosporin co-treated with Ketamine] results in decreased expression of ARF3 mRNA | CTD | PMID:16635253 | Arf3 | Rat | lead(0) | decreases expression | ISO | ARF3 (Homo sapiens) | 6480464 | Lead results in decreased expression of ARF3 mRNA | CTD | PMID:19921347 | Arf3 | Rat | maneb | multiple interactions | ISO | Arf3 (Mus musculus) | 6480464 | [Maneb co-treated with Paraquat] results in decreased expression of ARF3 mRNA; [Paraquat co-treated with Maneb] more ... | CTD | PMID:18386188|PMID:36117858 | Arf3 | Rat | methoxychlor | decreases expression | EXP | | 6480464 | Methoxychlor results in decreased expression of ARF3 mRNA | CTD | PMID:21782745 | Arf3 | Rat | miconazole | increases expression | ISO | Arf3 (Mus musculus) | 6480464 | Miconazole results in increased expression of ARF3 mRNA | CTD | PMID:27462272 | Arf3 | Rat | N-methyl-4-phenylpyridinium | increases expression | ISO | Arf3 (Mus musculus) | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of ARF3 protein | CTD | PMID:26558463 | Arf3 | Rat | nickel atom | increases expression | ISO | ARF3 (Homo sapiens) | 6480464 | Nickel results in increased expression of ARF3 mRNA | CTD | PMID:24768652 | Arf3 | Rat | nicotine | multiple interactions | ISO | Arf3 (Mus musculus) | 6480464 | [Nicotine co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of ARF3 mRNA; Nicotine inhibits the reaction more ... | CTD | PMID:20230807 | Arf3 | Rat | nitrates | multiple interactions | ISO | Arf3 (Mus musculus) | 6480464 | [Particulate Matter results in increased abundance of Nitrates] which results in increased expression of ARF3 more ... | CTD | PMID:35964746 | Arf3 | Rat | ozone | multiple interactions | EXP | | 6480464 | [Ozone co-treated with Chlorine] results in decreased expression of ARF3 mRNA | CTD | PMID:18636392 | Arf3 | Rat | paclitaxel | affects response to substance | ISO | ARF3 (Homo sapiens) | 6480464 | ARF3 protein affects the susceptibility to Paclitaxel | CTD | PMID:16217747 | Arf3 | Rat | paracetamol | decreases expression | ISO | ARF3 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of ARF3 mRNA | CTD | PMID:21420995 | Arf3 | Rat | paracetamol | increases expression | ISO | ARF3 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of ARF3 mRNA | CTD | PMID:26690555 | Arf3 | Rat | paraquat | multiple interactions | ISO | Arf3 (Mus musculus) | 6480464 | [Maneb co-treated with Paraquat] results in decreased expression of ARF3 mRNA; [Paraquat co-treated with Maneb] more ... | CTD | PMID:18386188|PMID:36117858 | Arf3 | Rat | pentachlorophenol | increases expression | ISO | Arf3 (Mus musculus) | 6480464 | Pentachlorophenol results in increased expression of ARF3 mRNA | CTD | PMID:23892564 | Arf3 | Rat | perfluorooctane-1-sulfonic acid | decreases expression | EXP | | 6480464 | perfluorooctane sulfonic acid results in decreased expression of ARF3 mRNA | CTD | PMID:18692542 | Arf3 | Rat | pirinixic acid | decreases expression | ISO | Arf3 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of ARF3 mRNA | CTD | PMID:18445702 | Arf3 | Rat | quercetin | increases expression | ISO | ARF3 (Homo sapiens) | 6480464 | Quercetin results in increased expression of ARF3 protein | CTD | PMID:17292933 | Arf3 | Rat | Salinomycin | decreases expression | ISO | ARF3 (Homo sapiens) | 6480464 | salinomycin results in decreased expression of ARF3 mRNA | CTD | PMID:19682730 | Arf3 | Rat | sodium arsenite | increases expression | ISO | ARF3 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of ARF3 mRNA | CTD | PMID:34032870 | Arf3 | Rat | sunitinib | decreases expression | ISO | ARF3 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of ARF3 mRNA | CTD | PMID:31533062 | Arf3 | Rat | thapsigargin | decreases expression | ISO | ARF3 (Homo sapiens) | 6480464 | Thapsigargin results in decreased expression of ARF3 mRNA | CTD | PMID:29453283 | Arf3 | Rat | thapsigargin | increases expression | EXP | | 6480464 | Thapsigargin results in increased expression of ARF3 protein | CTD | PMID:35544339 | Arf3 | Rat | thiram | decreases expression | ISO | ARF3 (Homo sapiens) | 6480464 | Thiram results in decreased expression of ARF3 mRNA | CTD | PMID:38568856 | Arf3 | Rat | titanium dioxide | decreases methylation | ISO | Arf3 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of ARF3 gene; titanium dioxide results in decreased methylation more ... | CTD | PMID:35295148 | Arf3 | Rat | titanium dioxide | increases methylation | ISO | Arf3 (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of ARF3 gene | CTD | PMID:35295148 | Arf3 | Rat | tocopherol | increases expression | ISO | Arf3 (Mus musculus) | 6480464 | Tocopherols results in increased expression of ARF3 mRNA | CTD | PMID:17654050 | Arf3 | Rat | triphenyl phosphate | affects expression | ISO | ARF3 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of ARF3 mRNA | CTD | PMID:37042841 | Arf3 | Rat | triptonide | increases expression | ISO | Arf3 (Mus musculus) | 6480464 | triptonide results in increased expression of ARF3 mRNA | CTD | PMID:33045310 | Arf3 | Rat | valproic acid | affects expression | ISO | Arf3 (Mus musculus) | 6480464 | Valproic Acid affects the expression of ARF3 mRNA | CTD | PMID:17292431 | Arf3 | Rat | valproic acid | increases expression | ISO | ARF3 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of ARF3 mRNA | CTD | PMID:23179753 | Arf3 | Rat | valproic acid | affects expression | ISO | ARF3 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of ARF3 mRNA | CTD | PMID:25979313 | Arf3 | Rat | venlafaxine hydrochloride | decreases expression | EXP | | 6480464 | Venlafaxine Hydrochloride results in decreased expression of ARF3 mRNA | CTD | PMID:25423262 | Arf3 | Rat | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of ARF3 mRNA | CTD | PMID:23034163 | Arf3 | Rat | vitamin E | increases expression | ISO | ARF3 (Homo sapiens) | 6480464 | Vitamin E results in increased expression of ARF3 mRNA | CTD | PMID:19244175 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















