Pla1a (phospholipase A1 member A) - Rat Genome Database

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Gene: Pla1a (phospholipase A1 member A) Rattus norvegicus
Analyze
Symbol: Pla1a
Name: phospholipase A1 member A
RGD ID: 621261
Description: Predicted to enable phospholipase A1 activity. Predicted to be involved in lipid catabolic process. Predicted to be located in acrosomal membrane. Predicted to be active in extracellular space. Orthologous to human PLA1A (phospholipase A1 member A); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: phosphatidylserine-specific phospholipase A1; Ps-pla1; Pspla1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81175,825,626 - 75,863,296 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1175,825,585 - 75,878,165 (+)EnsemblGRCr8
mRatBN7.21162,320,112 - 62,357,779 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1162,320,493 - 62,357,779 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1171,132,637 - 71,170,302 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01163,794,884 - 63,832,553 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01162,845,532 - 62,883,163 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01164,882,024 - 64,919,714 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1164,882,288 - 64,919,579 (+)Ensemblrn6Rnor6.0
Rnor_5.01167,166,387 - 67,203,665 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41164,099,837 - 64,137,353 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1161,822,091 - 61,859,256 (+)NCBICelera
RGSC_v3.11164,157,425 - 64,194,945 (+)NCBI
Cytogenetic Map11q21NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
(1->4)-beta-D-glucan  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
6alpha-methylprednisolone  (ISO)
acetamide  (EXP)
aflatoxin B1  (EXP,ISO)
alpha-Zearalanol  (EXP)
amitrole  (EXP)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsenite(3-)  (ISO)
atrazine  (EXP)
azithromycin  (EXP)
beclomethasone  (ISO)
benzo[a]pyrene  (ISO)
beta-naphthoflavone  (EXP)
bilirubin IXalpha  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
buta-1,3-diene  (ISO)
cadmium dichloride  (EXP)
carbon nanotube  (ISO)
carbonyl sulfide  (EXP)
cefaloridine  (EXP)
CGP 52608  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
clotrimazole  (EXP)
cobalt dichloride  (EXP)
corticosterone  (EXP)
Cuprizon  (EXP)
cyclosporin A  (ISO)
dexamethasone  (ISO)
dibutyl phthalate  (EXP)
dioxygen  (ISO)
diuron  (EXP)
ethyl methanesulfonate  (ISO)
fenofibrate  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
furan  (EXP)
genistein  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
glycidol  (EXP)
GW 4064  (ISO)
GW 7647  (EXP,ISO)
leflunomide  (EXP)
lipopolysaccharide  (ISO)
methamphetamine  (EXP)
methimazole  (EXP)
methotrexate  (ISO)
mono(2-ethylhexyl) phthalate  (EXP,ISO)
monobenzyl phthalate  (ISO)
Monobutylphthalate  (ISO)
monoethyl phthalate  (ISO)
Muraglitazar  (EXP)
N-nitrosodiethylamine  (EXP,ISO)
naphthalene  (ISO)
nickel atom  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
p-toluidine  (EXP)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
pirinixic acid  (ISO)
prednisolone  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
propiconazole  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SCH 23390  (EXP)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
Soman  (EXP)
Tesaglitazar  (EXP)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
troglitazone  (EXP,ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vincristine  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Serine phospholipid-specific phospholipase A that is secreted from activated platelets. A new member of the lipase family. Sato T, etal., J Biol Chem 1997 Jan 24;272(4):2192-8.
8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:11395520   PMID:15489334   PMID:23376485   PMID:23943622   PMID:24006456  


Genomics

Comparative Map Data
Pla1a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81175,825,626 - 75,863,296 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1175,825,585 - 75,878,165 (+)EnsemblGRCr8
mRatBN7.21162,320,112 - 62,357,779 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1162,320,493 - 62,357,779 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1171,132,637 - 71,170,302 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01163,794,884 - 63,832,553 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01162,845,532 - 62,883,163 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01164,882,024 - 64,919,714 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1164,882,288 - 64,919,579 (+)Ensemblrn6Rnor6.0
Rnor_5.01167,166,387 - 67,203,665 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41164,099,837 - 64,137,353 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1161,822,091 - 61,859,256 (+)NCBICelera
RGSC_v3.11164,157,425 - 64,194,945 (+)NCBI
Cytogenetic Map11q21NCBI
PLA1A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383119,597,885 - 119,629,811 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3119,597,808 - 119,629,816 (+)Ensemblhg38GRCh38
GRCh373119,316,732 - 119,348,658 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363120,799,436 - 120,831,342 (+)NCBIBuild 36Build 36hg18NCBI36
Build 343120,799,434 - 120,831,341NCBI
Celera3117,725,283 - 117,757,207 (+)NCBICelera
Cytogenetic Map3q13.33NCBI
HuRef3116,692,381 - 116,724,322 (+)NCBIHuRef
CHM1_13119,280,198 - 119,312,157 (+)NCBICHM1_1
T2T-CHM13v2.03122,317,610 - 122,349,514 (+)NCBIT2T-CHM13v2.0
Pla1a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391638,214,245 - 38,253,553 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1638,216,479 - 38,253,507 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381638,396,117 - 38,433,191 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1638,396,117 - 38,433,145 (-)Ensemblmm10GRCm38
MGSCv371638,396,203 - 38,433,225 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361638,315,356 - 38,352,378 (-)NCBIMGSCv36mm8
Celera1638,806,434 - 38,843,606 (-)NCBICelera
Cytogenetic Map16B3NCBI
cM Map1626.83NCBI
Pla1a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542719,297,938 - 19,335,825 (+)Ensembl
ChiLan1.0NW_00495542719,298,004 - 19,334,454 (+)NCBIChiLan1.0ChiLan1.0
PLA1A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22117,575,584 - 117,606,829 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13117,580,362 - 117,612,292 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03116,720,777 - 116,752,030 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13123,633,173 - 123,664,383 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3123,633,173 - 123,664,383 (+)EnsemblpanPan2panpan1.1
PLA1A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13323,222,217 - 23,262,603 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3323,236,161 - 23,288,651 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3323,252,379 - 23,292,764 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03323,460,284 - 23,500,933 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3323,474,593 - 23,500,910 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13323,262,901 - 23,303,070 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03323,298,489 - 23,338,887 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03323,867,996 - 23,908,366 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Pla1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602130,973,457 - 131,006,822 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365366,515,115 - 6,548,954 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365366,515,151 - 6,548,943 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLA1A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13140,638,521 - 140,665,961 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.113140,638,522 - 140,666,064 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213149,969,013 - 149,999,194 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PLA1A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12261,190,815 - 61,222,540 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2261,190,721 - 61,222,182 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666041105,091,764 - 105,122,399 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pla1a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473128,511,156 - 28,578,646 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473128,513,863 - 28,587,394 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Pla1a
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1423,347,479 - 23,384,350 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Pla1a
269 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:35
Count of miRNA genes:33
Interacting mature miRNAs:33
Transcripts:ENSRNOT00000038400
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)114644316891443168Rat
70208Niddm22Non-insulin dependent diabetes mellitus QTL 223.61blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)117330848796070872Rat
1598811Bp291Blood pressure QTL 2911.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)113330600878306008Rat
4889859Pur28Proteinuria QTL 2819.50.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)115892833699753367Rat
10755497Bp388Blood pressure QTL 3882.76arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)113294306789836615Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)113642841681428416Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)117385089499753367Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)113461876079618760Rat
2298551Neuinf10Neuroinflammation QTL 103.7nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)115893182292356038Rat
2312566Glom20Glomerulus QTL 203.60.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)115775483796071021Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112019354996351019Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)116796218499753367Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)117330831599753367Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)113674945981749459Rat
1581572Uae35Urinary albumin excretion QTL 350.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)115827236396350770Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)115107102196071021Rat
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)112252474682951192Rat
1598841Memor7Memory QTL 7exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)113330600878306008Rat
1581565Pur10Proteinuria QTL 100.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)115827236396350770Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)113674945981749459Rat
1300130Rf20Renal function QTL 204.44kidney glomerulus integrity trait (VT:0010546)kidney glomerulus diameter (CMO:0001166)113191546976915469Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)115441539196071021Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)113674945981749459Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)113674945981749459Rat
4889521Gluco62Glucose level QTL 622.820.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)116859932196497754Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)116985594399753367Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 161 91 90 59 92 59 6 355 192 11 140 80 92 31 14 14

Sequence


Ensembl Acc Id: ENSRNOT00000077727   ⟹   ENSRNOP00000071860
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1175,825,585 - 75,863,298 (+)Ensembl
mRatBN7.2 Ensembl1162,320,493 - 62,357,779 (+)Ensembl
Rnor_6.0 Ensembl1164,882,288 - 64,919,579 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000127091   ⟹   ENSRNOP00000108165
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1175,825,585 - 75,878,165 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000155316   ⟹   ENSRNOP00000101539
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1175,825,585 - 75,863,839 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000161617   ⟹   ENSRNOP00000103267
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1175,825,585 - 75,862,812 (+)Ensembl
RefSeq Acc Id: NM_138882   ⟹   NP_620237
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81175,825,626 - 75,863,296 (+)NCBI
mRatBN7.21162,320,112 - 62,357,779 (+)NCBI
Rnor_6.01164,882,434 - 64,919,714 (+)NCBI
Rnor_5.01167,166,387 - 67,203,665 (-)NCBI
RGSC_v3.41164,099,837 - 64,137,353 (+)RGD
Celera1161,822,091 - 61,859,256 (+)RGD
Sequence:
RefSeq Acc Id: XM_006248377   ⟹   XP_006248439
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81175,825,631 - 75,862,246 (+)NCBI
mRatBN7.21162,320,117 - 62,356,729 (+)NCBI
Rnor_6.01164,882,024 - 64,918,609 (+)NCBI
Rnor_5.01167,166,387 - 67,203,665 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_620237 (Get FASTA)   NCBI Sequence Viewer  
  XP_006248439 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH78727 (Get FASTA)   NCBI Sequence Viewer  
  BAA13672 (Get FASTA)   NCBI Sequence Viewer  
  EDM11222 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000071860
  ENSRNOP00000071860.1
  ENSRNOP00000108165
GenBank Protein P97535 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_620237   ⟸   NM_138882
- Peptide Label: precursor
- UniProtKB: P97535 (UniProtKB/Swiss-Prot),   A6IR69 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006248439   ⟸   XM_006248377
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000071860   ⟸   ENSRNOT00000077727
Ensembl Acc Id: ENSRNOP00000101539   ⟸   ENSRNOT00000155316
Ensembl Acc Id: ENSRNOP00000108165   ⟸   ENSRNOT00000127091
Ensembl Acc Id: ENSRNOP00000103267   ⟸   ENSRNOT00000161617
Protein Domains
Lipase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P97535-F1-model_v2 AlphaFold P97535 1-456 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621261 AgrOrtholog
BioCyc Gene G2FUF-21271 BioCyc
Ensembl Genes ENSRNOG00000057153 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000077727 ENTREZGENE
  ENSRNOT00000077727.2 UniProtKB/Swiss-Prot
  ENSRNOT00000127091 ENTREZGENE
Gene3D-CATH 3.40.50.1820 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7124402 IMAGE-MGC_LOAD
InterPro AB_hydrolase UniProtKB/Swiss-Prot
  Lipase/vitellogenin UniProtKB/Swiss-Prot
  Lipase_LIPH UniProtKB/Swiss-Prot
  Lipase_N UniProtKB/Swiss-Prot
  TAG_lipase UniProtKB/Swiss-Prot
KEGG Report rno:85311 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93173 IMAGE-MGC_LOAD
NCBI Gene 85311 ENTREZGENE
PANTHER PHOSPHOLIPASE A1 MEMBER A UniProtKB/Swiss-Prot
  PTHR11610 UniProtKB/Swiss-Prot
Pfam Lipase UniProtKB/Swiss-Prot
PhenoGen Pla1a PhenoGen
PIRSF Lipoprotein_lipase_LIPH UniProtKB/Swiss-Prot
PRINTS TAGLIPASE UniProtKB/Swiss-Prot
PROSITE LIPASE_SER UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000057153 RatGTEx
Superfamily-SCOP SSF53474 UniProtKB/Swiss-Prot
UniProt A0ABK0L0G5_RAT UniProtKB/TrEMBL
  A0ABK0L2T1_RAT UniProtKB/TrEMBL
  A0ABK0LZP9_RAT UniProtKB/TrEMBL
  A6IR69 ENTREZGENE, UniProtKB/TrEMBL
  P97535 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-02-19 Pla1a  phospholipase A1 member A  Pspla1  phosphatidylserine-specific phospholipase A1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_regulation activity is inhibited by diisopropyl fluorophosphate 633839