Megf6 (multiple EGF-like-domains 6) - Rat Genome Database

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Gene: Megf6 (multiple EGF-like-domains 6) Rattus norvegicus
Analyze
Symbol: Megf6
Name: multiple EGF-like-domains 6
RGD ID: 621188
Description: Predicted to enable calcium ion binding activity and scavenger receptor activity. Predicted to be involved in endocytosis. Predicted to be located in extracellular region. Orthologous to human MEGF6 (multiple EGF like domains 6); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 7,12-dimethyltetraphene; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: EGF-like domain-containing protein 3; EGF-like protein 3; EGF-like-domain, multiple 3; Egfl3; epidermal growth factor-like protein 3; LOC100911486; multiple EGF-like domain protein 3; multiple EGF-like domains protein 6; multiple epidermal growth factor-like domains 6; multiple epidermal growth factor-like domains protein 6; multiple epidermal growth factor-like domains protein 6-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85170,020,699 - 170,121,557 (+)NCBIGRCr8
mRatBN7.25164,738,272 - 164,839,142 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5164,738,352 - 164,839,139 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5167,442,460 - 167,543,339 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05169,263,873 - 169,364,753 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05169,226,389 - 169,327,272 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05171,588,901 - 171,620,947 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5171,472,273 - 171,620,947 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05175,061,318 - 175,092,801 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45171,022,566 - 171,050,436 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5162,949,005 - 163,049,274 (+)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-azacytidine  (ISO)
7,12-dimethyltetraphene  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (ISO)
diethylstilbestrol  (EXP)
dorsomorphin  (ISO)
fenvalerate  (EXP)
fulvestrant  (ISO)
genistein  (ISO)
gentamycin  (EXP)
GW 4064  (ISO)
indometacin  (ISO)
methapyrilene  (ISO)
nickel atom  (ISO)
ozone  (ISO)
paracetamol  (EXP)
paraquat  (EXP)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
propanal  (ISO)
quercetin  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
sunitinib  (ISO)
T-2 toxin  (ISO)
testosterone  (ISO)
tetraphene  (ISO)
thimerosal  (ISO)
titanium dioxide  (ISO)
Trapidil  (EXP)
triptonide  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
2. Identification of high-molecular-weight proteins with multiple EGF-like motifs by motif-trap screening. Nakayama M, etal., Genomics 1998 Jul 1;51(1):27-34.
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Megf6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85170,020,699 - 170,121,557 (+)NCBIGRCr8
mRatBN7.25164,738,272 - 164,839,142 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5164,738,352 - 164,839,139 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5167,442,460 - 167,543,339 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05169,263,873 - 169,364,753 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05169,226,389 - 169,327,272 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05171,588,901 - 171,620,947 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5171,472,273 - 171,620,947 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05175,061,318 - 175,092,801 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45171,022,566 - 171,050,436 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5162,949,005 - 163,049,274 (+)NCBICelera
Cytogenetic Map5q36NCBI
MEGF6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3813,487,951 - 3,624,786 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl13,487,951 - 3,611,508 (-)EnsemblGRCh38hg38GRCh38
GRCh3713,404,515 - 3,528,072 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3613,394,366 - 3,517,919 (-)NCBINCBI36Build 36hg18NCBI36
Build 3413,429,640 - 3,471,169NCBI
Celera12,657,546 - 2,783,180 (-)NCBICelera
Cytogenetic Map1p36.32NCBI
HuRef12,699,245 - 2,824,471 (-)NCBIHuRef
CHM1_113,391,530 - 3,514,788 (-)NCBICHM1_1
T2T-CHM13v2.012,994,964 - 3,134,506 (-)NCBIT2T-CHM13v2.0
Megf6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394154,255,156 - 154,360,178 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4154,255,187 - 154,360,170 (+)EnsemblGRCm39 Ensembl
GRCm384154,170,704 - 154,275,721 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4154,170,730 - 154,275,713 (+)EnsemblGRCm38mm10GRCm38
MGSCv374153,544,822 - 153,649,830 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364153,014,513 - 153,119,521 (+)NCBIMGSCv36mm8
Celera4156,454,674 - 156,563,044 (+)NCBICelera
Cytogenetic Map4E2NCBI
cM Map483.89NCBI
Megf6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554868,029,200 - 8,102,876 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554868,029,200 - 8,103,395 (+)NCBIChiLan1.0ChiLan1.0
LOC100975124
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21224,697,347 - 224,825,216 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11223,342,714 - 223,470,778 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012,155,295 - 2,283,034 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.113,283,100 - 3,405,920 (-)NCBIpanpan1.1PanPan1.1panPan2
MEGF6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1558,058,833 - 58,145,855 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl558,059,031 - 58,146,193 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha558,069,548 - 58,159,767 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0558,260,038 - 58,346,898 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl558,260,236 - 58,347,762 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1558,274,617 - 58,361,420 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0558,143,351 - 58,230,183 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0558,533,553 - 58,620,411 (-)NCBIUU_Cfam_GSD_1.0
Megf6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505829,101,134 - 29,196,271 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936737269,629 - 364,809 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MEGF6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl665,053,389 - 65,141,380 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1665,055,533 - 65,141,449 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2659,798,036 - 59,826,365 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103225737
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120128,075,329 - 128,195,618 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605432,339,756 - 32,476,481 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Megf6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248186,867,706 - 6,945,383 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Megf6
439 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:40
Count of miRNA genes:37
Interacting mature miRNAs:39
Transcripts:ENSRNOT00000000169
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5121846814166846814Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5126424772166875058Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5127798274166875058Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5127798274166875058Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5128506074166875058Rat
634349Bp139Blood pressure QTL 1390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5128924607166875058Rat
738018Anxrr4Anxiety related response QTL 45.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)5130130159166875058Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5131345754166875058Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5132717196165560427Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5143069996166846814Rat
631272Lanf1Left ventricular atrial natriuretic factor QTL 112heart left ventricle natriuretic peptide A amount (VT:0010596)heart left ventricle natriuretic peptide A level (CMO:0002165)5151113452166875058Rat
1549904Neuinf1Neuroinflammation QTL 130nervous system integrity trait (VT:0010566)blood T lymphocyte count (CMO:0000110)5154828214166875058Rat

Markers in Region
BE096131  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25164,838,929 - 164,839,101 (+)MAPPERmRatBN7.2
Rnor_6.05171,620,738 - 171,620,909NCBIRnor6.0
Rnor_5.05175,092,592 - 175,092,763UniSTSRnor5.0
Celera5163,049,065 - 163,049,236UniSTS
RH 3.4 Map51159.6UniSTS
Cytogenetic Map5q36UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2
Low 29 17 14 4 14 46 20 29 11
Below cutoff 3 14 37 26 15 26 2 2 28 8 10 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000000169   ⟹   ENSRNOP00000000169
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5164,738,352 - 164,839,139 (+)Ensembl
Rnor_6.0 Ensembl5171,478,608 - 171,620,947 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000055386   ⟹   ENSRNOP00000052252
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5164,803,091 - 164,839,139 (+)Ensembl
Rnor_6.0 Ensembl5171,472,273 - 171,620,380 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000091417   ⟹   ENSRNOP00000074085
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5164,738,352 - 164,839,139 (+)Ensembl
Rnor_6.0 Ensembl5171,478,555 - 171,620,935 (+)Ensembl
RefSeq Acc Id: NM_022955   ⟹   NP_075244
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85170,020,778 - 170,121,554 (+)NCBI
mRatBN7.25164,738,352 - 164,839,139 (+)NCBI
Rnor_6.05171,588,901 - 171,620,947 (+)NCBI
Rnor_5.05175,061,318 - 175,092,801 (+)NCBI
RGSC_v3.45171,022,566 - 171,050,436 (+)RGD
Celera5162,949,005 - 163,049,274 (+)RGD
Sequence:
RefSeq Acc Id: XM_039110728   ⟹   XP_038966656
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85170,020,699 - 170,121,557 (+)NCBI
mRatBN7.25164,738,273 - 164,839,142 (+)NCBI
RefSeq Acc Id: XM_039110730   ⟹   XP_038966658
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85170,085,518 - 170,121,557 (+)NCBI
mRatBN7.25164,803,098 - 164,839,142 (+)NCBI
Protein Sequences
Protein RefSeqs NP_075244 (Get FASTA)   NCBI Sequence Viewer  
  XP_038966656 (Get FASTA)   NCBI Sequence Viewer  
  XP_038966658 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAA32462 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000000169
  ENSRNOP00000000169.7
  ENSRNOP00000052252
  ENSRNOP00000052252.5
  ENSRNOP00000074085.2
GenBank Protein O88281 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_075244   ⟸   NM_022955
- Peptide Label: precursor
- UniProtKB: O88281 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_038966656   ⟸   XM_039110728
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038966658   ⟸   XM_039110730
- Peptide Label: isoform X2
- UniProtKB: D4AA94 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000052252   ⟸   ENSRNOT00000055386
RefSeq Acc Id: ENSRNOP00000000169   ⟸   ENSRNOT00000000169
RefSeq Acc Id: ENSRNOP00000074085   ⟸   ENSRNOT00000091417
Protein Domains
EGF-like   EMI

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O88281-F1-model_v2 AlphaFold O88281 1-1574 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621188 AgrOrtholog
BioCyc Gene G2FUF-38961 BioCyc
Ensembl Genes ENSRNOG00000000156 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000000169 ENTREZGENE
  ENSRNOT00000000169.7 UniProtKB/TrEMBL
  ENSRNOT00000055386 ENTREZGENE
  ENSRNOT00000055386.5 UniProtKB/TrEMBL
  ENSRNOT00000091417.2 UniProtKB/TrEMBL
Gene3D-CATH Laminin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tie2 ligand-binding domain superfamily UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro cEGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF-like_Ca-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF-type_Asp/Asn_hydroxyl_site UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_Ca-bd_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_extracell UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EMI_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Growth_fac_rcpt_cys_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Laminin_EGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MEGF10/SREC1/2-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:65049 UniProtKB/Swiss-Prot
NCBI Gene 65049 ENTREZGENE
PANTHER EGF-LIKE DOMAIN-CONTAINING PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  INTEGRIN BETA-LIKE PROTEIN A-RELATED UniProtKB/TrEMBL
  MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS PROTEIN UniProtKB/TrEMBL
  SCAVENGER RECEPTOR CLASS F UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam cEGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_CA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FXa_inhibition UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Laminin_EGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Megf6 PhenoGen
PRINTS EGFLAMININ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ASX_HYDROXYL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_CA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EMI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000000156 RatGTEx
SMART EGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_CA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_Lam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP EGF/Laminin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57184 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K769_RAT UniProtKB/TrEMBL
  D4AA94 ENTREZGENE, UniProtKB/TrEMBL
  F1LLY1_RAT UniProtKB/TrEMBL
  MEGF6_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Megf6  multiple EGF-like-domains 6  LOC100911486  multiple epidermal growth factor-like domains protein 6-like  Data merged from RGD:6492904 737654 PROVISIONAL
2012-07-05 LOC100911486  multiple epidermal growth factor-like domains protein 6-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-02-19 Megf6  multiple EGF-like-domains 6  Egfl3  EGF-like-domain, multiple 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Egfl3  EGF-like-domain, multiple 3    MEGF6  Name updated 1299863 APPROVED
2002-08-07 Egfl3  MEGF6      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_domains seven-transmembrane protein containing multiple cadherin and EGF-like motifs, and two homologues of Drosophila slit protein 68762