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Gene: Scd2 (stearoyl-Coenzyme A desaturase 2) Rattus norvegicus

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Symbol:

Scd2

Name:

stearoyl-Coenzyme A desaturase 2

RGD ID:

621177

Description:

Enables stearoyl-CoA 9-desaturase activity. Involved in myelination and response to fatty acid. Predicted to be located in endoplasmic reticulum. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human SCD (stearoyl-CoA desaturase); PARTICIPATES IN eicosanoid signaling pathway via peroxisome proliferator-activated receptor gamma; unsaturated fatty acid biosynthetic pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,2',4,4',5,5'-hexachlorobiphenyl.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

acyl-CoA desaturase 2; delta(9)-desaturase 2; delta-9 desaturase 2; fatty acid desaturase 2; Scd; stearoyl-CoA desaturase (delta-9-desaturase); stearoyl-CoA desaturase 2

RGD Orthologs

Mouse

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Mus musculus (house mouse):	Scd2 (stearoyl-Coenzyme A desaturase 2)	RGD	RGD
Other homologs ²
Homo sapiens (human):	SCD (stearoyl-CoA desaturase)	HGNC	EggNOG, Ensembl, OrthoDB, Panther
Alliance orthologs ³
Homo sapiens (human):	SCD (stearoyl-CoA desaturase)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Mus musculus (house mouse):	Scd2 (stearoyl-Coenzyme A desaturase 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	scdb (stearoyl-CoA desaturase b)	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	scdb (stearoyl-CoA desaturase b)	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Danio rerio (zebrafish):	scd (stearoyl-CoA desaturase (delta-9-desaturase))	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	scd (stearoyl-CoA desaturase (delta-9-desaturase))	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG15531	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	CG15531	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):	OLE1	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	OLE1	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	fat-5	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	fat-7	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG9743	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	CG9743	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	CG9747	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	CG9747	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	Desat1	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Desat1	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Desat2	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Desat2	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Fad2	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Fad2	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	fat-6	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	scd	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	scd	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	253,118,377 - 253,131,436 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	253,117,655 - 253,128,874 (+)	Ensembl				GRCr8
mRatBN7.2	1	243,169,171 - 243,182,231 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	243,169,236 - 243,182,232 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	251,319,535 - 251,332,589 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	258,015,961 - 258,029,023 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	250,669,684 - 250,682,738 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	264,059,374 - 264,072,433 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	264,059,374 - 264,072,433 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	271,502,294 - 271,515,353 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	249,358,105 - 249,371,164 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	238,984,066 - 238,997,125 (+)	NCBI		Celera
RGSC_v3.1	1	249,616,941 - 249,630,001 (+)	NCBI
Cytogenetic Map	1	q54	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

atherosclerosis (ISO)

demyelinating disease (ISO)

Experimental Liver Cirrhosis (ISO)

Weight Gain (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

1-naphthyl isothiocyanate (EXP)

17alpha-ethynylestradiol (EXP,ISO)

17beta-estradiol (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,6-trinitrotoluene (EXP)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO)

2,4-dinitrotoluene (EXP)

2-amino-2-deoxy-D-glucopyranose (ISO)

3,3',4,4',5-pentachlorobiphenyl (EXP,ISO)

3,3',5,5'-tetrabromobisphenol A (EXP)

3,4-methylenedioxymethamphetamine (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

3H-1,2-dithiole-3-thione (EXP)

4,4'-diaminodiphenylmethane (EXP)

4,4'-sulfonyldiphenol (EXP,ISO)

acetamide (EXP)

aflatoxin B1 (ISO)

aldehydo-D-glucosamine (ISO)

Aroclor 1254 (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenous acid (ISO)

atrazine (EXP)

benzo[a]pyrene (ISO)

beta-D-glucosamine (ISO)

bexarotene (EXP)

bezafibrate (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (EXP)

C60 fullerene (EXP)

calcidiol (EXP)

carbon nanotube (ISO)

carboplatin (EXP)

choline (ISO)

cisplatin (EXP)

conjugated linoleic acid (ISO)

copper atom (EXP)

copper(0) (EXP)

curcumin (EXP)

dexamethasone (EXP,ISO)

dextran sulfate (ISO)

diarsenic trioxide (ISO)

dioxygen (ISO)

doxorubicin (EXP,ISO)

endosulfan (EXP)

ethanol (EXP,ISO)

fenofibrate (ISO)

fenvalerate (EXP)

folic acid (ISO)

genistein (EXP)

gentamycin (EXP)

glyphosate (ISO)

griseofulvin (ISO)

Heptachlor epoxide (ISO)

indometacin (EXP)

iron atom (EXP)

iron(0) (EXP)

L-methionine (ISO)

monosodium L-glutamate (ISO)

N-methyl-4-phenylpyridinium (EXP,ISO)

N-nitrosodiethylamine (EXP,ISO)

N-nitrosodimethylamine (EXP)

nickel sulfate (ISO)

oroxylin A (ISO)

ozone (EXP)

paracetamol (EXP,ISO)

paraquat (EXP)

perfluorohexanesulfonic acid (ISO)

perfluorooctane-1-sulfonic acid (EXP,ISO)

perfluorooctanoic acid (EXP,ISO)

phenobarbital (EXP,ISO)

phenylephrine (EXP)

PhIP (EXP)

pirinixic acid (EXP,ISO)

pravastatin (ISO)

raloxifene (EXP)

resveratrol (ISO)

rimonabant (ISO)

rotenone (EXP)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sodium dichromate (ISO)

succimer (ISO)

sulforaphane (ISO)

testosterone cypionate (ISO)

tetrachloromethane (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

triadimefon (EXP)

Tributyltin oxide (ISO)

troglitazone (ISO)

vinclozolin (EXP)

zaragozic acid A (ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

fatty acid biosynthetic process (IEA,TAS)

fatty acid metabolic process (IEA)

lipid metabolic process (IEA)

monounsaturated fatty acid biosynthetic process (IBA,ISO)

myelination (IEP)

response to fatty acid (IDA)

unsaturated fatty acid biosynthetic process (IBA,IEA)

Cellular Component

endoplasmic reticulum (IEA,ISO)

endoplasmic reticulum membrane (IBA,IEA)

membrane (IEA)

Molecular Function

acyl-CoA desaturase activity (IEA)

iron ion binding (IBA,IEA)

metal ion binding (IEA)

oxidoreductase activity (IEA)

oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water (IEA)

palmitoyl-CoA 9-desaturase activity (IBA,IEA,ISO)

stearoyl-CoA 9-desaturase activity (IBA,IDA,IEA,ISO,TAS)

Molecular Pathway Annotations Click to see Annotation Detail View

eicosanoid signaling pathway via peroxisome proliferator-activated receptor gamma (IEA)

unsaturated fatty acid biosynthetic pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Regulation of oleoyl-CoA synthesis in the peripheral nervous system: demonstration of a link with myelin synthesis.	Garbay B, etal., J Neurochem 1998 Oct;71(4):1719-26.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	Structure and regulation of rat liver microsomal stearoyl-CoA desaturase gene.	Mihara K J Biochem. 1990 Dec;108(6):1022-9.
6.	Expression and regulation of the SCD2 desaturase in the rat ovary.	Moreau C, etal., Biol Reprod. 2006 Jan;74(1):75-87. Epub 2005 Oct 5.
7.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
8.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
9.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
10.	GOA pipeline	RGD automated data pipeline
11.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
12.	Expression and regulation of delta5-desaturase, delta6-desaturase, stearoyl-coenzyme A (CoA) desaturase 1, and stearoyl-CoA desaturase 2 in rat testis.	Saether T, etal., Biol Reprod 2003 Jul;69(1):117-24. Epub 2003 Feb 19.
13.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
14.	(-)-Epigallocatechin-3-Gallate Ameliorates Atherosclerosis and Modulates Hepatic Lipid Metabolic Gene Expression in Apolipoprotein E Knockout Mice: Involvement of TTC39B.	Wang W, etal., Front Pharmacol. 2018 Mar 9;9:195. doi: 10.3389/fphar.2018.00195. eCollection 2018.

Additional References at PubMed

PMID:7800118	PMID:10716735	PMID:15489334	PMID:16443825	PMID:21266672

Genomics

Comparative Map Data

Scd2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	253,118,377 - 253,131,436 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	253,117,655 - 253,128,874 (+)	Ensembl				GRCr8
mRatBN7.2	1	243,169,171 - 243,182,231 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	243,169,236 - 243,182,232 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	251,319,535 - 251,332,589 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	258,015,961 - 258,029,023 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	250,669,684 - 250,682,738 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	264,059,374 - 264,072,433 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	264,059,374 - 264,072,433 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	271,502,294 - 271,515,353 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	249,358,105 - 249,371,164 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	238,984,066 - 238,997,125 (+)	NCBI		Celera
RGSC_v3.1	1	249,616,941 - 249,630,001 (+)	NCBI
Cytogenetic Map	1	q54	NCBI

Scd2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	19	44,282,115 - 44,295,303 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	19	44,282,113 - 44,295,303 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	19	44,293,676 - 44,306,864 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	19	44,293,674 - 44,306,864 (+)	Ensembl			mm10	GRCm38
MGSCv37	19	44,368,166 - 44,381,354 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	19	44,347,399 - 44,360,171 (+)	NCBI		MGSCv36	mm8
Celera	19	45,067,400 - 45,080,568 (+)	NCBI		Celera
Cytogenetic Map	19	C3	NCBI
cM Map	19	37.98	NCBI

Variants

Variants in Scd2
185 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	651
Count of miRNA genes:	279
Interacting mature miRNAs:	368
Transcripts:	ENSRNOT00000018090, ENSRNOT00000075397
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1578778	Pur4	Proteinuria QTL 4	3.3	0.003	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	1	160111531	262090437	Rat
1354646	Kidm18	Kidney mass QTL 18	5.7		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	160573753	266453731	Rat
1354652	Kidm20	Kidney mass QTL 20	4.3		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	186658830	266453731	Rat
2293674	Bss39	Bone structure and strength QTL 39	7.1	0.0001	femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	1	210980612	255980612	Rat
61327	Eae7	Experimental allergic encephalomyelitis QTL 7	5.6		body mass (VT:0001259)	change in body weight (CMO:0002045)	1	226175591	270518180	Rat
1578775	Iddm21	Insulin dependent diabetes mellitus QTL 21	4.13		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	245782829	270518180	Rat
1600395	Niddm69	Non-insulin dependent diabetes mellitus QTL 69	4.14	0.0002	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	1	205233991	267096252	Rat
1578763	Kidm29	Kidney mass QTL 29	3.3	0.0001	kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	1	218829748	263829748	Rat
1354624	Cm35	Cardiac mass QTL35	5.7		heart left ventricle mass (VT:0007031)	calculated heart weight (CMO:0000073)	1	186658830	266453731	Rat
1600396	Niddm68	Non-insulin dependent diabetes mellitus QTL 68	4.97	0.0003	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	205233991	267096252	Rat
631837	Niddm35	Non-insulin dependent diabetes mellitus QTL 35		0.01	blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	1	248619887	269633915	Rat
1600397	Edcs4	Endometrial carcinoma susceptibility QTL 4	2.2		uterus morphology trait (VT:0001120)	percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)	1	176288899	270518180	Rat
631836	Stl31	Serum triglyceride level QTL 31	4.64	5e-06	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	1	247133834	270518180	Rat
1549837	Hcar15	Hepatocarcinoma resistance QTL 15		0.05	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	162548015	270518180	Rat
1600388	Niddm67	Non-insulin dependent diabetes mellitus QTL 67	5.84	0.000004	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	205233991	267096252	Rat
2293694	Bss38	Bone structure and strength QTL 38	7.05	0.0001	femur strength trait (VT:0010010)	femur stiffness (CMO:0001674)	1	210980612	255980612	Rat
1598853	Memor3	Memory QTL 3	4.5		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	1	152919152	268496042	Rat
1578759	Uae30	Urinary albumin excretion QTL 30	3.3	0.003	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	160111531	262090437	Rat
1300108	Rf8	Renal function QTL 8	3.75		renal blood flow trait (VT:2000006)	absolute change in renal vascular resistance (CMO:0001900)	1	237995023	269633915	Rat
734767	Niddm57	Non-insulin dependent diabetes mellitus QTL 57			body mass (VT:0001259)	body weight (CMO:0000012)	1	233480549	270108840	Rat
1358898	Bp255	Blood pressure QTL 255	3.6		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	200449456	256003563	Rat
631215	Stl8	Serum triglyceride level QTL 8	9.27	0.0001	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	1	234540191	270518180	Rat
631843	Bw116	Body weight QTL 116	4.1	0.016	abdominal adipose amount (VT:1000220)	abdominal fat pad weight (CMO:0000088)	1	233480549	270108840	Rat
731175	Uae20	Urinary albumin excretion QTL 20	3.5	0.0018	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	207163993	269633915	Rat
2300175	Bmd40	Bone mineral density QTL 40	15.4	0.0001	femur mineral mass (VT:0010011)	bone mineral density (CMO:0001226)	1	210980612	255980612	Rat
1354661	Bw33	Body weight QTL 33	5.2		body mass (VT:0001259)	body weight (CMO:0000012)	1	160573753	266453731	Rat
724538	Kidm1	Kidney mass QTL 1	3.2		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	223134011	262090599	Rat
2293655	Bss36	Bone structure and strength QTL 36	10.66	0.0001	femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	1	210980612	255980612	Rat
724531	Uae5	Urinary albumin excretion QTL 5	4		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	1	160111426	262090599	Rat
2314011	Gluco56	Glucose level QTL 56			blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	209203273	254203273	Rat
734769	Niddm58	Non-insulin dependent diabetes mellitus QTL 58			body mass (VT:0001259)	body weight (CMO:0000012)	1	225108840	270108840	Rat
724533	Rf51	Renal function QTL 51	5.3	0.0002	kidney plasma flow trait (VT:0005524)	renal plasma flow (CMO:0001914)	1	228180370	266453608	Rat
1354580	Scort1	Serum corticosterone level QTL 1	3.4		blood corticosterone amount (VT:0005345)	blood corticosterone level (CMO:0001172)	1	154961463	266453731	Rat
634313	Niddm43	Non-insulin dependent diabetes mellitus QTL 43			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	208479811	269633915	Rat
70211	Niddm24	Non-insulin dependent diabetes mellitus QTL 24	3.79		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	224633915	269633915	Rat
724552	Glom2	Glomerulus QTL 2	3.3	0.0001	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)	1	232312773	270518180	Rat
2316896	Gluco57	Glucose level QTL 57	7.2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	238398865	255849249	Rat
1358916	Kidm22	Kidney mass QTL 22	3.32		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	1	212738576	257738576	Rat
2312564	Glom18	Glomerulus QTL 18	2.4	0.003	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	1	194786607	262083703	Rat
2292218	Kidm35	Kidney mass QTL 35			kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	1	208798288	253798288	Rat
61400	Niddm1	Non-insulin dependent diabetes mellitus QTL 1	11		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	228180243	255849249	Rat
1354610	Bw34	Body weight QTL 34	4.1		body mass (VT:0001259)	body weight (CMO:0000012)	1	160573753	266453731	Rat
2293700	Bmd27	Bone mineral density QTL 27	6.6	0.0001	femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	1	210980612	255980612	Rat
2293701	Bmd34	Bone mineral density QTL 34	8.3	0.0001	femur strength trait (VT:0010010)	femoral neck ultimate force (CMO:0001703)	1	210980612	255980612	Rat
7387289	Uae45	Urinary albumin excretion QTL 45	2.86	0.0021	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	233204160	270518180	Rat
1581544	Rf52	Renal function QTL 52		0.05	urine total protein amount (VT:0000032)	urine protein excretion rate to body weight ratio (CMO:0001099)	1	241569529	269633915	Rat
1600363	Hc6	Hypercalciuria QTL 6	2.7		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	1	210980612	255980612	Rat
631536	Lnnr2	Liver neoplastic nodule remodeling QTL 2	2.9	0.0005	liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)	1	243953669	270518180	Rat
738032	Hcas5	Hepatocarcinoma susceptibility QTL 5	3.12		liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	185857683	270518180	Rat
2302040	Pia35	Pristane induced arthritis QTL 35	3.8	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	1	226175591	270518180	Rat
631669	Iddm9	Insulin dependent diabetes mellitus QTL 9	2.8	0.039	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	1	233349180	270518180	Rat
7394701	Uae46	Urinary albumin excretion QTL 46	3.6	0.0056	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	210980612	255980612	Rat
1598821	Rf55	Renal function QTL 55	6.3		renal blood flow trait (VT:2000006)	ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239)	1	228174566	270518180	Rat

Markers in Region

D1Got350

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	243,177,527 - 243,177,760 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	264,067,730 - 264,067,962	NCBI	Rnor6.0
Rnor_5.0	1	271,510,650 - 271,510,882	UniSTS	Rnor5.0
RGSC_v3.4	1	249,366,461 - 249,366,693	UniSTS	RGSC3.4
Celera	1	238,992,422 - 238,992,654	UniSTS
Cytogenetic Map	1	q54	UniSTS

M26270

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	243,179,211 - 243,179,353 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	264,069,414 - 264,069,555	NCBI	Rnor6.0
Rnor_5.0	1	271,512,334 - 271,512,475	UniSTS	Rnor5.0
RGSC_v3.4	1	249,368,145 - 249,368,286	UniSTS	RGSC3.4
Celera	1	238,994,106 - 238,994,247	UniSTS
Cytogenetic Map	1	q54	UniSTS

BE107760

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	243,180,034 - 243,180,196 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	264,070,237 - 264,070,398	NCBI	Rnor6.0
Rnor_5.0	1	271,513,157 - 271,513,318	UniSTS	Rnor5.0
RGSC_v3.4	1	249,368,968 - 249,369,129	UniSTS	RGSC3.4
Celera	1	238,994,929 - 238,995,090	UniSTS
RH 3.4 Map	1	1617.41	UniSTS
Cytogenetic Map	1	q54	UniSTS

RH133521

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	243,180,749 - 243,180,949 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	264,070,952 - 264,071,151	NCBI	Rnor6.0
Rnor_5.0	1	271,513,872 - 271,514,071	UniSTS	Rnor5.0
RGSC_v3.4	1	249,369,683 - 249,369,882	UniSTS	RGSC3.4
Celera	1	238,995,644 - 238,995,843	UniSTS
RH 3.4 Map	1	1616.02	UniSTS
Cytogenetic Map	1	q54	UniSTS

RH143783

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	1	253,130,681 - 253,130,919 (+)	Marker Load Pipeline
mRatBN7.2	1	243,181,476 - 243,181,714 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	264,071,679 - 264,071,916	NCBI	Rnor6.0
Rnor_5.0	1	271,514,599 - 271,514,836	UniSTS	Rnor5.0
RGSC_v3.4	1	249,370,410 - 249,370,647	UniSTS	RGSC3.4
Celera	1	238,996,371 - 238,996,608	UniSTS
RH 3.4 Map	1	1618.11	UniSTS
Cytogenetic Map	1	q54	UniSTS

RH140028

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	243,181,390 - 243,181,595 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	264,071,593 - 264,071,797	NCBI	Rnor6.0
Rnor_5.0	1	271,514,513 - 271,514,717	UniSTS	Rnor5.0
RGSC_v3.4	1	249,370,324 - 249,370,528	UniSTS	RGSC3.4
Celera	1	238,996,285 - 238,996,489	UniSTS
RH 3.4 Map	1	1616.92	UniSTS
Cytogenetic Map	1	q54	UniSTS

AU050019

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	243,172,504 - 243,173,610 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	264,062,707 - 264,063,812	NCBI	Rnor6.0
Rnor_5.0	1	271,505,627 - 271,506,732	UniSTS	Rnor5.0
RGSC_v3.4	1	249,361,438 - 249,362,543	UniSTS	RGSC3.4
Celera	1	238,987,399 - 238,988,504	UniSTS
Cytogenetic Map	1	q54	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_031841	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB032243	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC105487	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF036761	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC061737	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473986	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ212986	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ213614	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ229444	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U67995	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000075397 ⟹ ENSRNOP00000067809

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	253,117,655 - 253,128,874 (+)	Ensembl
mRatBN7.2 Ensembl	1	243,169,236 - 243,182,232 (+)	Ensembl
Rnor_6.0 Ensembl	1	264,059,374 - 264,072,433 (+)	Ensembl

RefSeq Acc Id:

NM_031841 ⟹ NP_114029

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	253,118,377 - 253,131,436 (+)	NCBI
mRatBN7.2	1	243,169,171 - 243,182,231 (+)	NCBI
Rnor_6.0	1	264,059,374 - 264,072,433 (+)	NCBI
Rnor_5.0	1	271,502,294 - 271,515,353 (+)	NCBI
RGSC_v3.4	1	249,358,105 - 249,371,164 (+)	RGD
Celera	1	238,984,066 - 238,997,125 (+)	RGD

Sequence:

show sequence

CTGGGCTAGGGATGGGCACAATGCGGTGTTGGTGTCTGCAGTATTCTACTCCTGGACACCGGTG
GCCTGCAAGTGCGCTTTTGGCGTCCTCTCATTTTTCTATCCTTATCTCCGTCCGCGGCTGCCTT
GGCCAGCCAGTTTTTGATTTTTTATCTGTTCCTTGATCGATACAAAGAACCTAAGGACATACAG
GACATTAATACCCAACTGCCAGCTCTGGCCCAGGGCTTGTACTGTGCAGCGGGCTGGCTGCAGA
AACTTAAGTCATAACACTCTTTGTCGCTGAGGTCTGAAGCTCTCTGCACGTTCTCATCCCTGGG
AACGTGACCCCAGCATCCGACGCCAAGATGCCGGCTCACATACTGCAAGAGATCTCTGGCTCTT
ACTCGGCCACCACCACAATCACAGCGCCACCTTCTGGGGGACAGCAGAATGGAGGAGAGAAGTT
TGAAAAGAATCCTCACCACTGGGGAGCAGATGTTCGCCCTGAAATTAAAGATGACCTATACGAC
CCCAGCTACCAGGATGAGGAGGGGCCCCCGCCCAAGCTGGAGTACGTCTGGAGGAACATCATCC
TCATGGCCCTGCTGCACATTGGAGCCCTGTACGGGATCACACTGGTCCCCTCCTGCAAGGTCTA
CACCTGCCTCTTTGCATATTTGTACTACGTAATCAGCGCCCTGGGCATCACAGCCGGGGCTCAT
CGCCTGTGGAGCCACAGGACTTACAAGGCTCGGCTGCCCCTGAGGCTCTTTCTCATCATCGCCA
ACACCATGGCATTCCAGAACGATGTGTACGAATGGGCCCGGGATCACCGCGCCCACCACAAGTT
CTCAGAGACACACGCCGACCCTCACAACTCCCGCCGTGGCTTTTTCTTCTCTCACGTGGGTTGG
CTGCTTGTGCGCAAACACCCGGCTGTCAAAGAGAAGGGCGGAAAGCTGGACATGTCTGACCTGA
AAGCTGAGAAGCTGGTGATGTTCCAGAGGAGGTATTACAAGCCCGGCCTCCTGCTCATGTGCTT
CATCCTGCCCACGCTGGTGCCCTGGTACTGCTGGGGTGAGACGTTTGTAAACAGCCTGTGCGTC
AGCACTTTCTTACGGTACGCTGTGGTGCTCAACGCCACCTGGCTGGTGAACAGCGCCGCCCACC
TCTATGGATATCGCCCCTACGACAAGAACATCAGCTCTCGGGAGAACATCCTGGTGTCGATGGG
AGCTGTGGGCGAGGGCTTCCACAACTACCATCACGCCTTCCCCTATGACTACTCTGCCAGTGAG
TACCGCTGGCACATCAACTTCACCACGTTCTTCATCGACTGCATGGCCCTCCTGGGCCTGGCTT
ATGACCGGAAGAGGGTGTCCAAGGCCGCTGTCTTAGCCAGGATTAAGAGAACTGGGGAGGAGAG
CTGCAAGAGTGGCTGAGTTCGGGGTCTTCCAGTTCCTGTTCCAAGAGCCGGCTTGGCAGAGGCT
TACTGTTCTGTTAATTAACTACTGAGTATTGCTACCCAGATGCTAAAATGATGAAGTTAACCCA
TTCTGGTACAGTATTGTAAAACGGACAAATATCGGAAGTCAACAGCTCTACCTTTTGATGCTAA
GCTGTTCTCCCCTTCTATCTTCTTTTCCCGTTGTCTTTTTCTTCGCTTTGTCCCCAATGACCTC
ACCCCTCATCGCCTCCCCTAAGCCAGCAGCCACTCCGCTGTAGTTCAGAGTTCACCTTCCAGAG
CGTACCAGCTTTTCAAGGGTCTACAGTAAAGGTTCACGCCCCAGCCCCAACTTAACGTTGCTCC
AAGTTACAGATAGAAGAAAAATCTTGAGAAATTTCTCCTGTTATTTTAGTCCAGACTTTGCCAG
ATGGAATGGGAGAAAAAATAGTTTTATTTGGCAGAGAGCTTGCGAAGTGGGTAAATCTTAAGGG
GCCAAATTCAACACTCGGGCTGTGATTCATCAAAATTGTGGGAGAGGGGGATCTCCTGTGATCA
GGCTCCGCTCCGTCTGGCCGAGGTGCTGGCGTCTCTTGACACAGCGTGCCTCCTCTCCTAATTC
TGATTGGGTGACAGCCGTGGAACTTTGTGACACTAAAATATGGCAACACATCGGTATCTCAGTG
TACTTTAGGCTAAAGATTTAAAAAAATAGAGAAGTGAAAAACAATTTGTAGGAAAAGTGGTCTT
TCCTAAAATAAGATTTTCTTTTCCTTTCATAACAAGGACCTGGGGCCAGGCGTCGTGGCACCCG
CCTCAAAACAGTTGAGAGGAGAGGGGCAGGTGGGTCTCTGAGTTTGAAGCCAGCCAGGGCTAGA
TAGTGAGGCCTTGTCTCAAATAGAAAAGCCAACAATTAGCAGGACACACGGAGCCGGGGGTCCT
CTTGCGAGGCGTGTCTGGAATCCATGAGGGCGGTCGCTCGTGGTTTTTGAGCTTCCTGTGAGCT
GCACCCCCAGACACTTGTAATTCCTGTTCTTCCGTCTTTCGGATGCAGGTTGCTCCCACAAATT
CAGGATAGCTATGGCGTTTCCATGCATCCCACAATGGAAGGAGTGTAAGACTTGAGCTTGAGTC
ACAGCTAAAACCCAGAAGACACAAAGTCAGTCTGTCCTGGATCCTACAAACACTCAACGAGTGC
CTCCCTCTGGAAAAGATGGTGAACACCTTCCTTCCACTGTTGGGCAGTGGACAGGGAAGTTGGA
GGTCGCTGTAGGCAGCTCCAAGGTTTCTAGGGGCACCTTGCCAGGGGACCTCACAACTTTGGCG
GTCTCTAGTGGAGCAGGTTAGGTTTTAGCTCCCTTTGGTTCCCGCTGTGCTTTGTGGTAAGGCT
TTTCCCTGGGCTGTTGCCTCATTCCTCACTAGCTCTGTGACCAGGTAGGACTCTGGGATACATG
GCTGAAAGCTCTTTTGCTCTACCACATCTGCCTCTCTTTCCCTACCCATTTTTTTGTGTTTCGG
GGTGGTATTTTTGTGGTGGTTGTTTTGTTTTATTTCTTCTTTCCTCTTTGACGTTTAGTCTTGC
TCTAGGCAGAAACGTCCTGGATATTTACGGTCAGTAAAGATGTCCGGTCCCAGCAGAGATACAA
CCTCTATCTGCAGTAGGTAGAGAAGGCTGTCCCTTTCCGGTGGCTTTCAGATTCTCCACCTCTA
TCCCTCCCAGGCCTCTGATATTCTTTAAACTTTAAAGGAAAAGTTTGGCCGACTTTCTAGAAAC
ATCCCTGGCTCAGAGAGGCTCTCTGTCTCCTCGGTTGTTCTAAAACAAATGGTCCGGGTGGTGT
GGGTGCTGGCCCAAGACTCGATTCCTCTGAGTTAGGGCAGAGCATGCTCCCTGCACTCAGCAAA
GCCTCTCGGGCTGATCAGTGCTCCTGGGTGATGCTGTGGTGCTTTTAGGAGGAAGACAGTGTTG
GCTGGCTGGAAAGCATGACAGTTAAGGTTGTGTTCTTAAGTGCCTCAGTTTGAAAGCTTTGGCT
AGGGTAGGAGATCTGAGATGCCGTGGACTTTGCAGAAGAGATTTTGTGCAGCAACGCAGAAGCC
TGGCTGTGTTAAGATTGGCTGTACAGGATAGCGAATGCTGTGGTTGGAGGGCACAGTCTTCCCG
TGTTAGTTAAATAGAGAGGCTTTAGGACGTCTCTGCGCCCACTTGAAGGTAGCCTTATCCTTTA
GCTGTTCGCTAAAATAGAATCCTTGAGAGATTGACAATATATTTGCTGGCCTGTCGCCCTATTC
CTTGGAGAGGCCTTTTGAATGGTTTTAATTCCACTGGTTATCCGGTGCCCACTTAATCAAATGT
GAAAAATAAAAAGCAGCTCTCTTCTTAGCCTGCCCCCGTGGATCTGAGGACCCTGTTAGATACA
GCTGTCGGTAAGGGTGTACCAGCTCACTAAGAAACACTACTGTCAAGATTTTAAAGCTCAGACC
AAGTGACACGTTAATAAGAAACTAAGATCTGATTGAATTTTCTAACAGTCCTTGCCTCGTGGAC
ACGCTAAAATTCGACTTGGGTGCCTTACCTCTTTTCTAACTAGTGTTACTCATGGGCCTGCGCT
CCCTTCCTCTGCGGATTCCTTAGAACCGGAGAGCCTGTAAGTGTGACAGGCTCAAAACTGGCCT
GGCTGGAGGGTTAGGTGGACTTTGATCTGCAGTGTTCCCTCTGGGGTCTTCGTTTGGGGAATAT
TTCTTGGGGCTGTTTTGCTGAAGTGCCCGTAGCTGATGGATGGTGGAAGTAATTTGAACGTACG
CGATTTGTAGGTTTTGTTATTTGTTTTAAGATTTAAAGGCTGGTTGTAGCATTTAAAAGTGAAA
GCTTTTTCTTCCTGGTTTGCTAGTGTTCTGCGTGTCTTCTTTAGTTGAAATAGGTTAGTGGAGA
AGTTAAGAAAGCGGTGGCCGTGTTACGCTGGTGGTGAAGGCCAGGGCCGCCTACAAACTCTCAG
TTTTGTTTTGTTTTGTTTTTTTATAACAGTCCCACTCTGACAATAATGAGTTCACTCCTTGGAT
AAGGTTGTTAATGAGGGAAGAGCCCTTCAGACCTAATCAGCTCTTACTGGACCCAGCTGTCAAC
ACTGTTGCATTGGGGATTAAGTTTCCAACCCCGTGAATCATGGGACAGACTCAAACCGTAGCAC
TGGGCATGTCGCCTAACAATATAATGTGACTCAGTATTCTGTGAGACATGGGATAATATTCCTG
ACCTACCTCCACGGGTAGGTGCGAGCATGAGCAAATGCTCTTTATAAAACATTTGGGGATCCTC
AGCAGAGGAGTATTTAAGTCCTGCACATTTTTATAGTAACCGTCCACCATGGACTTGACACGTG
CCTATGTCCCAGACGACATTGTTAATCTACATCATTCTTCTCAGAGGTTGAATGGATGCATTAG
ATAATGTATACTCATTGCTATGGAAACCTGCAGGACTCCTTTTCCTTCCTTGGGTGGGATTTTT
TTTTCCTTTATTATGTGCAACAGTAGCTATTTGTAATCTAATAATTTTCATTAATACCAACTCT
GAAAGTATTTCTACTCATCTGAGGTTGTGTTTGTTCATAATAAAATGAAATGGATCTGACTGC

hide sequence

Protein Sequences


Protein RefSeqs	NP_114029	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAB39620	(Get FASTA)	NCBI Sequence Viewer
	AAB88865	(Get FASTA)	NCBI Sequence Viewer
	AAH61737	(Get FASTA)	NCBI Sequence Viewer
	BAA92436	(Get FASTA)	NCBI Sequence Viewer
	EDL94279	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000067809
GenBank Protein	Q6P7B9	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_114029 ⟸ NM_031841

- UniProtKB:

Q9JMC9 (UniProtKB/Swiss-Prot), Q64066 (UniProtKB/Swiss-Prot), Q6P7B9 (UniProtKB/Swiss-Prot), M0RDU8 (UniProtKB/TrEMBL), A6JHF6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPAHILQEISGSYSATTTITAPPSGGQQNGGEKFEKNPHHWGADVRPEIKDDLYDPSYQDEEGP
PPKLEYVWRNIILMALLHIGALYGITLVPSCKVYTCLFAYLYYVISALGITAGAHRLWSHRTYK
ARLPLRLFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLVRKHPAV
KEKGGKLDMSDLKAEKLVMFQRRYYKPGLLLMCFILPTLVPWYCWGETFVNSLCVSTFLRYAVV
LNATWLVNSAAHLYGYRPYDKNISSRENILVSMGAVGEGFHNYHHAFPYDYSASEYRWHINFTT
FFIDCMALLGLAYDRKRVSKAAVLARIKRTGEESCKSG

hide sequence

Ensembl Acc Id:

ENSRNOP00000067809 ⟸ ENSRNOT00000075397

Protein Domains

Fatty acid desaturase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6P7B9-F1-model_v2	AlphaFold	Q6P7B9	1-358	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13690938

Promoter ID:

EPDNEW_R1463

Type:

multiple initiation site

Name:

Scd2_1

Description:

stearoyl-Coenzyme A desaturase 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	264,059,412 - 264,059,472	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:621177	AgrOrtholog
BioCyc Gene	G2FUF-55591	BioCyc
Ensembl Genes	ENSRNOG00000046005	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000075397	ENTREZGENE
IMAGE_CLONE	IMAGE:5599134	IMAGE-MGC_LOAD
InterPro	Acyl-CoA_DS	UniProtKB/Swiss-Prot
	FA_desaturase_dom	UniProtKB/Swiss-Prot
	FADS-1_CS	UniProtKB/Swiss-Prot
KEGG Report	rno:83792	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:72380	IMAGE-MGC_LOAD
NCBI Gene	83792	ENTREZGENE
PANTHER	PTHR11351	UniProtKB/Swiss-Prot
	STEAROYL-COA DESATURASE 2	UniProtKB/Swiss-Prot
Pfam	FA_desaturase	UniProtKB/Swiss-Prot
PhenoGen	Scd2	PhenoGen
PRINTS	FACDDSATRASE	UniProtKB/Swiss-Prot
PROSITE	FATTY_ACID_DESATUR_1	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000046005	RatGTEx
UniProt	A6JHF6	ENTREZGENE, UniProtKB/TrEMBL
	ACOD2_RAT	UniProtKB/Swiss-Prot
	M0RDU8	ENTREZGENE, UniProtKB/TrEMBL
	Q64066	ENTREZGENE
	Q6P7B9	ENTREZGENE
	Q9JMC9	ENTREZGENE
UniProt Secondary	Q64066	UniProtKB/Swiss-Prot
	Q9JMC9	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-02-20	Scd2	stearoyl-Coenzyme A desaturase 2	Scd	stearoyl-CoA desaturase (delta-9-desaturase)	Name and Symbol changed	629549	APPROVED
2008-09-18	Scd	stearoyl-CoA desaturase (delta-9-desaturase)	Scd2	stearoyl-Coenzyme A desaturase 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-20	Scd2	stearoyl-Coenzyme A desaturase 2			Symbol and Name status set to approved	1299863	APPROVED
2002-08-07	Scd2	stearoyl-Coenzyme A desaturase 2			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_expression	predominantly expressed in the peripheral nervous system	633983

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - CTD

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - CTD

Imported Annotations - KEGG (archival)