Imported Disease Annotations - ClinVarTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | familial adult myoclonic epilepsy 5 | | ISO | RNPEP (Homo sapiens) | 8554872 | ClinVar Annotator: match by term: Epilepsy more ... | ClinVar | PMID:28492532 | gastrointestinal stromal tumor | | ISO | RNPEP (Homo sapiens) | 8554872 | ClinVar Annotator: match by term: Gastrointestinal stromal tumor | ClinVar | PMID:28492532 | genetic disease | | ISO | RNPEP (Homo sapiens) | 8554872 | ClinVar Annotator: match by term: Inborn genetic diseases | ClinVar | | Hypokalemic Periodic Paralysis, Type 1 | | ISO | RNPEP (Homo sapiens) | 8554872 | ClinVar Annotator: match by term: Hypokalemic periodic paralysis and type 1 | ClinVar | PMID:28492532 | parathyroid carcinoma | | ISO | RNPEP (Homo sapiens) | 8554872 | ClinVar Annotator: match by term: Parathyroid carcinoma | ClinVar | PMID:28492532 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Imported Disease Annotations - CTD
Gene-Chemical Interaction Annotations Click to see Annotation Detail View
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References
References - curated
| # | Reference Title | Reference Citation |
| 1. | Aminopeptidase B: a processing enzyme secreted and associated with the plasma membrane of rat pheochromocytoma (PC12) cells. | Balogh A, etal., J Cell Sci. 1998 Jan;111 ( Pt 2):161-9. |
| 2. | Aminopeptidase B from the rat testis is a bifunctional enzyme structurally related to leukotriene-A4 hydrolase. | Cadel S, etal., Proc Natl Acad Sci U S A 1997 Apr 1;94(7):2963-8. |
| 3. | Renin-angiotensin system-regulating aminopeptidase activities are modified in the pineal gland of rats with breast cancer induced by N-methyl-nitrosourea. | Carrera MP, etal., Cancer Invest. 2006 Mar;24(2):149-53. |
| 4. | Congenic mapping and sequence analysis of the Renin locus. | Flister MJ, etal., Hypertension. 2013 Apr;61(4):850-6. doi: 10.1161/HYPERTENSIONAHA.111.01008. Epub 2013 Mar 4. |
| 5. | Miniglucagon (MG)-generating endopeptidase, which processes glucagon into MG, is composed of N-arginine dibasic convertase and aminopeptidase B. | Fontes G, etal., Endocrinology. 2005 Feb;146(2):702-12. Epub 2004 Nov 11. |
| 6. | Aminopeptidase B is structurally related to leukotriene-A4 hydrolase but is not a bifunctional enzyme with epoxide hydrolase activity. | Fukasawa KM, etal., Biochem J 1999 May 1;339 ( Pt 3):497-502. |
| 7. | Molecular cloning and expression of rat liver aminopeptidase B. | Fukasawa KM, etal., J Biol Chem 1996 Nov 29;271(48):30731-5. |
| 8. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 9. | Rat ISS GO annotations from GOA human gene data--August 2006 | GOA data from the GO Consortium |
| 10. | Characterization of the metal-binding site in aminopeptidase B. | Hirose J, etal., Biol Pharm Bull. 2006 Dec;29(12):2378-82. |
| 11. | Rat ISS GO annotations from MGI mouse gene data--August 2006 | MGD data from the GO Consortium |
| 12. | Electronic Transfer of LocusLink and RefSeq Data | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
| 13. | Expression of aminopeptidase B in the developing and adult rat retina. | Piesse C, etal., Exp Eye Res. 2004 Nov;79(5):639-48. |
| 14. | Insulin-regulated aminopeptidase/placental leucil Aminopeptidase (IRAP/P-lAP) and angiotensin IV-forming activities are modified in serum of rats with breast cancer induced by N-methyl-nitrosourea. | Pilar Carrera M, etal., Anticancer Res. 2006 Mar-Apr;26(2A):1011-4. |
| 15. | Activities of aminopeptidases in a rat saline model of volume hypertension. | Prieto I, etal., Horm Metab Res. 1998 May;30(5):246-8. |
| 16. | Developmental and ageing changes in aminopeptidase activities in selected tissues of the rat. | Ramirez M, etal., Experientia. 1993 Apr 15;49(4):300-3. |
| 17. | Soluble and membrane-bound leucyl- and arginyl-aminopeptidase activities in subcellular fractions of young and adult rat brains. | Ramirez M, etal., Rev Esp Fisiol. 1990 Dec;46(4):393-7. |
| 18. | GOA pipeline | RGD automated data pipeline |
| 19. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 20. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
| 21. | Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. | Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11. |
| 22. | Dysfunction of central angiotensinergic aminopeptidase activity in spontaneously hypertensive rats. | Wright JW, etal., Neurosci Lett. 1985 Nov 11;61(3):351-6. |
Additional References at PubMed
| PMID:10467730 | PMID:12119107 | PMID:18547641 | PMID:18571504 | PMID:19056867 | PMID:19199708 | PMID:21237246 | PMID:23376485 | PMID:23533145 | PMID:27068509 | PMID:32357304 |
Genomics
Comparative Map Data
| Rnpep (Rattus norvegicus - Norway rat) |
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| RNPEP (Homo sapiens - human) |
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| Rnpep (Mus musculus - house mouse) |
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| Rnpep (Chinchilla lanigera - long-tailed chinchilla) |
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| RNPEP (Pan paniscus - bonobo/pygmy chimpanzee) |
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| RNPEP (Canis lupus familiaris - dog) |
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| Rnpep (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| RNPEP (Sus scrofa - pig) |
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| RNPEP (Chlorocebus sabaeus - green monkey) |
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| Rnpep (Heterocephalus glaber - naked mole-rat) |
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Variants
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Variants in Rnpep
76 total Variants 
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