Cdh4 (cadherin 4) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Cdh4 (cadherin 4) Rattus norvegicus
Analyze
Symbol: Cdh4
Name: cadherin 4
RGD ID: 621091
Description: Predicted to enable calcium ion binding activity. Predicted to be involved in cell-cell adhesion. Predicted to act upstream of or within several processes, including heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; homophilic cell adhesion via plasma membrane adhesion molecules; and positive regulation of axon extension. Predicted to be located in plasma membrane. Orthologous to human CDH4 (cadherin 4); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: cadherin 4 type 1 R-cadherin (retinal); cadherin 4, type 1, R-cadherin (retinal); cadherin 4-like; cadherin-4; cadherin-4-like; Cdh4l; LOC102554066; R-CAD; R-cadherin; retinal cadherin
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83186,902,763 - 187,381,020 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3186,902,751 - 187,381,020 (+)EnsemblGRCr8
mRatBN7.23166,525,092 - 167,003,380 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3166,525,099 - 167,003,371 (+)EnsemblmRatBN7.2
Rnor_6.03175,220,520 - 175,283,144 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3175,144,495 - 175,279,761 (+)Ensemblrn6Rnor6.0
Rnor_5.03181,831,741 - 181,885,027 (-)NCBIRnor_5.0Rnor_5.0rn5
Celera3165,574,985 - 166,047,678 (-)NCBICelera
RGSC_v3.13168,759,379 - 168,874,826 (+)NCBI
Cytogenetic Map3q43NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dinitrobenzenesulfonic acid  (ISO)
2-palmitoylglycerol  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
8-Br-cAMP  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlordecone  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
clobetasol  (ISO)
clofibrate  (ISO)
dimethylarsinic acid  (ISO)
ethanol  (ISO)
folic acid  (ISO)
fulvestrant  (ISO)
geldanamycin  (ISO)
hexadecanoic acid  (ISO)
irinotecan  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
methapyrilene  (ISO)
methimazole  (EXP)
methotrexate  (ISO)
methylparaben  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N,N-diethyl-m-toluamide  (EXP)
N-nitrosodiethylamine  (EXP)
niclosamide  (ISO)
Nor-9-carboxy-delta9-THC  (ISO)
paracetamol  (ISO)
paraquat  (EXP)
permethrin  (EXP)
potassium chromate  (ISO)
progesterone  (ISO)
Ptaquiloside  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
titanium dioxide  (ISO)
triazines  (ISO)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
urethane  (ISO)
valproic acid  (EXP,ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IEA)
plasma membrane  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Adult bone marrow-derived stem cells use R-cadherin to target sites of neovascularization in the developing retina. Dorrell MI, etal., Blood 2004 May 1;103(9):3420-7. Epub 2004 Jan 15.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8270638   PMID:9531566   PMID:14586016   PMID:15117735   PMID:15905612  


Genomics

Comparative Map Data
Cdh4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83186,902,763 - 187,381,020 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3186,902,751 - 187,381,020 (+)EnsemblGRCr8
mRatBN7.23166,525,092 - 167,003,380 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3166,525,099 - 167,003,371 (+)EnsemblmRatBN7.2
Rnor_6.03175,220,520 - 175,283,144 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3175,144,495 - 175,279,761 (+)Ensemblrn6Rnor6.0
Rnor_5.03181,831,741 - 181,885,027 (-)NCBIRnor_5.0Rnor_5.0rn5
Celera3165,574,985 - 166,047,678 (-)NCBICelera
RGSC_v3.13168,759,379 - 168,874,826 (+)NCBI
Cytogenetic Map3q43NCBI
CDH4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382061,252,261 - 61,940,617 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2061,252,261 - 61,940,617 (+)Ensemblhg38GRCh38
GRCh372059,827,317 - 60,515,673 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362059,260,952 - 59,945,694 (+)NCBIBuild 36Build 36hg18NCBI36
Build 342059,260,953 - 59,945,694NCBI
Celera2056,566,480 - 57,250,388 (+)NCBICelera
Cytogenetic Map20q13.33NCBI
HuRef2056,854,804 - 57,296,777 (+)NCBIHuRef
CHM1_12059,728,415 - 60,417,358 (+)NCBICHM1_1
T2T-CHM13v2.02063,037,438 - 63,731,679 (+)NCBIT2T-CHM13v2.0
Cdh4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392179,084,228 - 179,541,166 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2179,084,224 - 179,541,166 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm382179,442,423 - 179,899,377 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2179,442,431 - 179,899,373 (+)Ensemblmm10GRCm38
MGSCv372179,177,183 - 179,634,080 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv362179,371,975 - 179,825,813 (+)NCBIMGSCv36mm8
Celera2183,531,405 - 183,982,406 (+)NCBICelera
Cytogenetic Map2H4NCBI
cM Map2101.86NCBI
Cdh4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555282,043,648 - 2,220,640 (-)Ensembl
ChiLan1.0NW_0049555282,040,373 - 2,594,602 (-)NCBIChiLan1.0ChiLan1.0
CDH4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22167,009,075 - 67,721,867 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12067,002,225 - 67,714,988 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02057,595,158 - 58,306,115 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12058,943,597 - 59,629,795 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2058,943,614 - 59,629,795 (+)EnsemblpanPan2panpan1.1
CDH4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12445,749,589 - 46,063,960 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2445,782,133 - 46,064,028 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2444,795,625 - 45,301,679 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02446,416,026 - 46,921,118 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2446,416,037 - 46,921,085 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12445,518,675 - 46,023,036 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02445,639,296 - 46,145,886 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02446,399,447 - 46,899,845 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cdh4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640193,830,727 - 194,225,393 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365149,563,847 - 9,675,636 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365149,284,385 - 9,679,036 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDH4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1760,959,190 - 61,451,878 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11760,959,236 - 61,454,154 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21768,534,287 - 68,980,434 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CDH4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.122,281,712 - 2,373,281 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl22,277,958 - 2,372,351 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605050,241,185 - 50,353,963 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cdh4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474127,331,496 - 27,855,390 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474127,331,436 - 27,858,474 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Cdh4
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v15156,515,367 - 156,986,829 (+)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:91
Count of miRNA genes:68
Interacting mature miRNAs:74
Transcripts:ENSRNOT00000032405, ENSRNOT00000071022
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3152055202189428310Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3142898802187898802Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)3145335553189428310Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3151075912189428310Rat
1298068Bp167Blood pressure QTL 1670.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3161492708189428310Rat
1582256Insul9Insulin level QTL 94.40.0016blood insulin amount (VT:0001560)absolute change in serum insulin level (CMO:0002038)3155759447189428310Rat
1582248Insul7Insulin level QTL 73.90.0041blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)3155759447189428310Rat
1578666Vnigr1Vascular neointimal growth QTL 14.6artery morphology trait (VT:0002191)artery lumen area (CMO:0001409)3151075912189428310Rat
1300161Rf10Renal function QTL 103.57renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)3181611379189428310Rat
8552791Vie2Viral induced encephalitis QTL 24.1brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)3166376089189428310Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3151075912189428310Rat
1331726Bp208Blood pressure QTL 2083.129arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3161799270187311134Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3144575244189428310Rat
1582213Insul6Insulin level QTL 63.70.0009blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)3155759447189428310Rat
1598854Memor10Memory QTL 102exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)3166376089189428310Rat

Markers in Region
D3Got173  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23166,711,119 - 166,711,247 (+)MAPPERmRatBN7.2
Rnor_6.03174,975,534 - 174,975,661NCBIRnor6.0
Rnor_5.03182,131,958 - 182,132,085UniSTSRnor5.0
RGSC_v3.43168,663,050 - 168,663,178RGDRGSC3.4
RGSC_v3.43168,663,051 - 168,663,178UniSTSRGSC3.4
Celera3165,862,731 - 165,862,858UniSTS
RGSC_v3.13168,569,087 - 168,569,214RGD
RH 3.4 Map31516.8UniSTS
RH 3.4 Map31516.8RGD
RH 2.0 Map31030.8RGD
Cytogenetic Map3q43UniSTS
D3Mco35  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23166,863,347 - 166,863,549 (+)MAPPERmRatBN7.2
Rnor_6.03175,129,601 - 175,129,802NCBIRnor6.0
Rnor_5.03181,982,277 - 181,982,478UniSTSRnor5.0
RGSC_v3.43168,817,020 - 168,817,221UniSTSRGSC3.4
Celera3165,712,774 - 165,712,975UniSTS
Cytogenetic Map3q43UniSTS
D3Mco54  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23166,576,859 - 166,576,920 (+)MAPPERmRatBN7.2
mRatBN7.23166,576,742 - 166,576,920 (+)MAPPERmRatBN7.2
mRatBN7.23166,576,742 - 166,577,451 (+)MAPPERmRatBN7.2
Rnor_6.06137,628,455 - 137,629,225NCBIRnor6.0
Rnor_6.06137,628,455 - 137,628,634NCBIRnor6.0
Rnor_5.06146,624,975 - 146,625,745UniSTSRnor5.0
Rnor_5.06146,624,975 - 146,625,154UniSTSRnor5.0
RGSC_v3.43168,607,300 - 168,607,479UniSTSRGSC3.4
Celera3165,995,310 - 165,995,489UniSTS
Cytogenetic Map3q43UniSTS
D3Mco52  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23166,781,685 - 166,781,911 (+)MAPPERmRatBN7.2
Rnor_6.03175,047,040 - 175,047,265NCBIRnor6.0
Rnor_5.03182,062,569 - 182,062,794UniSTSRnor5.0
RGSC_v3.43168,734,934 - 168,735,159UniSTSRGSC3.4
Celera3165,793,043 - 165,793,268UniSTS
Cytogenetic Map3q43UniSTS
D3Mco59  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23166,653,001 - 166,653,176 (+)MAPPERmRatBN7.2
Rnor_6.03174,918,572 - 174,918,746NCBIRnor6.0
Rnor_5.03182,188,822 - 182,188,996UniSTSRnor5.0
RGSC_v3.43168,551,286 - 168,551,460UniSTSRGSC3.4
Celera3165,920,119 - 165,920,293UniSTS
Cytogenetic Map3q43UniSTS
D3Mco49  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23166,824,576 - 166,824,754 (+)MAPPERmRatBN7.2
Rnor_6.03175,089,893 - 175,090,068NCBIRnor6.0
Rnor_5.03182,019,813 - 182,019,988UniSTSRnor5.0
RGSC_v3.43168,777,829 - 168,778,004UniSTSRGSC3.4
Celera3165,750,260 - 165,750,435UniSTS
Cytogenetic Map3q43UniSTS
D3Mco51  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23166,793,175 - 166,793,325 (+)MAPPERmRatBN7.2
Rnor_6.03175,058,465 - 175,058,614NCBIRnor6.0
Rnor_5.03182,051,220 - 182,051,369UniSTSRnor5.0
RGSC_v3.43168,746,424 - 168,746,573UniSTSRGSC3.4
Celera3165,781,629 - 165,781,778UniSTS
Cytogenetic Map3q43UniSTS
D3Mco48  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23166,960,324 - 166,960,517 (+)MAPPERmRatBN7.2
Rnor_6.03175,240,740 - 175,240,932NCBIRnor6.0
Rnor_5.03181,873,002 - 181,873,194UniSTSRnor5.0
RGSC_v3.43168,939,719 - 168,939,911UniSTSRGSC3.4
Celera3165,617,037 - 165,617,229UniSTS
Cytogenetic Map3q43UniSTS
D3Mco56  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23166,689,940 - 166,690,121 (+)MAPPERmRatBN7.2
Rnor_6.03174,954,334 - 174,954,514NCBIRnor6.0
Rnor_5.03182,153,078 - 182,153,258UniSTSRnor5.0
RGSC_v3.43168,641,131 - 168,641,311UniSTSRGSC3.4
Celera3165,882,966 - 165,883,146UniSTS
Cytogenetic Map3q43UniSTS
D3Mco47  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23166,972,752 - 166,972,891 (+)MAPPERmRatBN7.2
Rnor_6.03175,252,524 - 175,252,662NCBIRnor6.0
Rnor_5.03181,861,272 - 181,861,410UniSTSRnor5.0
RGSC_v3.43168,952,067 - 168,952,205UniSTSRGSC3.4
Celera3165,604,983 - 165,605,121UniSTS
Cytogenetic Map3q43UniSTS
D3Mco50  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.03175,080,971 - 175,081,427NCBIRnor6.0
Rnor_5.03182,028,454 - 182,028,910UniSTSRnor5.0
RGSC_v3.43168,768,973 - 168,769,363UniSTSRGSC3.4
Celera3165,758,901 - 165,759,291UniSTS
Cytogenetic Map3q43UniSTS
D3Mco34  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23166,863,220 - 166,863,423 (+)MAPPERmRatBN7.2
Rnor_6.03175,129,474 - 175,129,676NCBIRnor6.0
Rnor_5.03181,982,403 - 181,982,605UniSTSRnor5.0
RGSC_v3.43168,816,893 - 168,817,095UniSTSRGSC3.4
Celera3165,712,900 - 165,713,102UniSTS
Cytogenetic Map3q43UniSTS
D3Mco57  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23166,692,672 - 166,692,920 (+)MAPPERmRatBN7.2
Rnor_6.03174,957,066 - 174,957,313NCBIRnor6.0
Rnor_5.03182,150,279 - 182,150,526UniSTSRnor5.0
RGSC_v3.43168,644,432 - 168,644,679UniSTSRGSC3.4
RGSC_v3.43168,643,863 - 168,644,679UniSTSRGSC3.4
Celera3165,880,167 - 165,880,414UniSTS
Cytogenetic Map3q43UniSTS
D3Mco53  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23166,585,339 - 166,585,506 (+)MAPPERmRatBN7.2
Rnor_6.06137,637,642 - 137,637,808NCBIRnor6.0
Rnor_5.06146,634,162 - 146,634,328UniSTSRnor5.0
RGSC_v3.43168,615,896 - 168,616,062UniSTSRGSC3.4
Celera3165,986,727 - 165,986,893UniSTS
Cytogenetic Map3q43UniSTS
D3Hmgc8  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23166,582,847 - 166,583,067 (+)MAPPERmRatBN7.2
Rnor_6.06137,635,152 - 137,635,369NCBIRnor6.0
Rnor_5.06146,631,672 - 146,631,889UniSTSRnor5.0
RGSC_v3.43168,613,406 - 168,613,623UniSTSRGSC3.4
Celera3165,989,166 - 165,989,383UniSTS
Cytogenetic Map3q43UniSTS
D3Hmgc7  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23166,671,506 - 166,671,654 (+)MAPPERmRatBN7.2
Rnor_6.03174,937,493 - 174,937,640NCBIRnor6.0
Rnor_5.03182,169,928 - 182,170,075UniSTSRnor5.0
RGSC_v3.43168,569,791 - 168,569,938UniSTSRGSC3.4
Celera3165,901,639 - 165,901,786UniSTS
Cytogenetic Map3q43UniSTS
BF401071  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23166,980,811 - 166,981,013 (+)MAPPERmRatBN7.2
Rnor_6.03175,260,583 - 175,260,784NCBIRnor6.0
Rnor_5.03181,853,150 - 181,853,351UniSTSRnor5.0
RGSC_v3.43168,960,126 - 168,960,327UniSTSRGSC3.4
Celera3165,596,861 - 165,597,062UniSTS
RH 3.4 Map31523.3UniSTS
Cytogenetic Map3q43UniSTS
BE100240  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23166,854,066 - 166,854,234 (+)MAPPERmRatBN7.2
Rnor_6.03175,120,324 - 175,120,491NCBIRnor6.0
Rnor_5.03181,991,588 - 181,991,755UniSTSRnor5.0
RGSC_v3.43168,807,743 - 168,807,910UniSTSRGSC3.4
Celera3165,722,085 - 165,722,252UniSTS
RH 3.4 Map31515.0UniSTS
Cytogenetic Map3q43UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
15 12 56 155 75 74 43 39 43 6 274 128 11 134 80 89 31 15 15

Sequence


Ensembl Acc Id: ENSRNOT00000082601   ⟹   ENSRNOP00000071000
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl3175,144,495 - 175,229,312 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000088026   ⟹   ENSRNOP00000074038
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3186,902,751 - 187,381,020 (+)Ensembl
mRatBN7.2 Ensembl3166,525,099 - 167,003,371 (+)Ensembl
Rnor_6.0 Ensembl3175,144,495 - 175,279,761 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000136921   ⟹   ENSRNOP00000110624
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3187,008,119 - 187,381,020 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000155267   ⟹   ENSRNOP00000104702
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3186,902,879 - 187,381,020 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000174135   ⟹   ENSRNOP00000103100
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3187,190,817 - 187,381,020 (+)Ensembl
RefSeq Acc Id: NM_001419540   ⟹   NP_001406469
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83186,902,763 - 187,381,020 (+)NCBI
mRatBN7.23166,525,092 - 167,003,380 (+)NCBI
RefSeq Acc Id: XM_039106754   ⟹   XP_038962682
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83187,000,913 - 187,381,020 (+)NCBI
mRatBN7.23166,623,231 - 167,003,380 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001406469 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962682 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAA13166 (Get FASTA)   NCBI Sequence Viewer  
  EDL88842 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000074038
  ENSRNOP00000110624
GenBank Protein Q63149 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Acc Id: ENSRNOP00000071000   ⟸   ENSRNOT00000082601
Ensembl Acc Id: ENSRNOP00000074038   ⟸   ENSRNOT00000088026
RefSeq Acc Id: XP_038962682   ⟸   XM_039106754
- Peptide Label: isoform X1
RefSeq Acc Id: NP_001406469   ⟸   NM_001419540
- Peptide Label: precursor
- UniProtKB: A0A0G2K728 (UniProtKB/TrEMBL),   A6KMD4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000104702   ⟸   ENSRNOT00000155267
Ensembl Acc Id: ENSRNOP00000110624   ⟸   ENSRNOT00000136921
Ensembl Acc Id: ENSRNOP00000103100   ⟸   ENSRNOT00000174135
Protein Domains
Cadherin

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q63149-F1-model_v2 AlphaFold Q63149 1-296 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621091 AgrOrtholog
BioCyc Gene G2FUF-46378 BioCyc
Ensembl Genes ENSRNOG00000052405 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000088026 ENTREZGENE
  ENSRNOT00000136921 ENTREZGENE
Gene3D-CATH Cadherins UniProtKB/Swiss-Prot
InterPro Cadherin UniProtKB/Swiss-Prot
  Cadherin-like_dom UniProtKB/Swiss-Prot
  Cadherin-like_sf UniProtKB/Swiss-Prot
  Cadherin_CS UniProtKB/Swiss-Prot
NCBI Gene 114588 ENTREZGENE
PANTHER CADHERIN-4 UniProtKB/Swiss-Prot
  PTHR24027 UniProtKB/Swiss-Prot
Pfam Cadherin UniProtKB/Swiss-Prot
PhenoGen Cdh4 PhenoGen
PRINTS CADHERIN UniProtKB/Swiss-Prot
PROSITE CADHERIN_1 UniProtKB/Swiss-Prot
  CADHERIN_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000052405 RatGTEx
SMART SM00112 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF49313 UniProtKB/Swiss-Prot
UniProt A0A0G2K728 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LMB4_RAT UniProtKB/TrEMBL
  A0ABK0LRF0_RAT UniProtKB/TrEMBL
  A0ABK0LWC5_RAT UniProtKB/TrEMBL
  A6KMD4 ENTREZGENE, UniProtKB/TrEMBL
  CADH4_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Cdh4  cadherin 4  LOC102554066  cadherin-4-like  Data merged from RGD:7638964 737654 PROVISIONAL
2013-12-18 LOC102554066  cadherin-4-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2013-08-01 Cdh4  cadherin 4  Cdh4l  cadherin 4-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-04-17 Cdh4l  cadherin 4-like  Cdh4  cadherin 4  Data merged from RGD:1586170 737654 PROVISIONAL
2008-03-13 Cdh4l  cadherin 4-like  Cdh4  cadherin 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-13 Cdh4  cadherin 4  LOC311710  similar to cadherin 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-19 LOC311710  similar to cadherin 4      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-01-20 Cdh4  cadherin 4    cadherin 4, type 1, R-cadherin (retinal)  Name updated 1299863 APPROVED
2002-08-07 Cdh4  cadherin 4, type 1, R-cadherin (retinal)      Symbol and Name status set to provisional 70820 PROVISIONAL