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Gene: Asic4 (acid sensing ion channel subunit family member 4) Rattus norvegicus

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Symbol:

Asic4

Name:

acid sensing ion channel subunit family member 4

RGD ID:

621068

Description:

Predicted to enable ligand-gated sodium channel activity. Predicted to be involved in sodium ion transmembrane transport. Predicted to act upstream of or within behavioral fear response. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human ASIC4 (acid sensing ion channel subunit family member 4); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; ammonium chloride.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

ACCN4; acid sensing ion channel 4; acid-sensing (proton-gated) ion channel family member 4; acid-sensing ion channel 4; amiloride-sensitive cation channel 4; amiloride-sensitive cation channel 4, pituitary; putative acid-sensing ion channel; Spasic; spinal chord ASIC; spinal cord ASIC

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ASIC4 (acid sensing ion channel subunit family member 4)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Asic4 (acid-sensing ion channel family member 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Asic4 (acid sensing ion channel subunit family member 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ASIC4 (acid sensing ion channel subunit family member 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ASIC4 (acid sensing ion channel subunit family member 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Asic4 (acid sensing ion channel subunit family member 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ASIC4 (acid sensing ion channel subunit family member 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ASIC4 (acid sensing ion channel subunit family member 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Asic4 (acid sensing ion channel subunit family member 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Asic4 (acid sensing ion channel subunit family member 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Asic4 (acid-sensing ion channel family member 4)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	ASIC4 (acid sensing ion channel subunit family member 4)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	asic4b (acid-sensing (proton-gated) ion channel family member 4b)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	asic4b (acid-sensing (proton-gated) ion channel family member 4b)	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	asic4a (acid-sensing (proton-gated) ion channel family member 4a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	asic4a (acid-sensing (proton-gated) ion channel family member 4a)	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	acd-1	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)
Caenorhabditis elegans (roundworm):	acd-1	Alliance	DIOPT (Ensembl Compara\|OMA\|PANTHER)
Caenorhabditis elegans (roundworm):	acd-2	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)
Caenorhabditis elegans (roundworm):	acd-2	Alliance	DIOPT (Ensembl Compara\|OMA\|PANTHER)
Caenorhabditis elegans (roundworm):	acd-4	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)
Caenorhabditis elegans (roundworm):	acd-4	Alliance	DIOPT (Ensembl Compara\|OMA\|PANTHER)
Caenorhabditis elegans (roundworm):	acd-5	Alliance	DIOPT (OrthoFinder\|OrthoInspector\|PANTHER)
Caenorhabditis elegans (roundworm):	delm-2	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)
Caenorhabditis elegans (roundworm):	delm-2	Alliance	DIOPT (Ensembl Compara\|OMA\|PANTHER)
Caenorhabditis elegans (roundworm):	flr-1	Alliance	DIOPT (OMA\|OrthoFinder\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	ppk	Alliance	DIOPT (OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	ppk13	Alliance	DIOPT (Ensembl Compara\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	ppk12	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	ppk12	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	ppk28	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	ppk28	Alliance	DIOPT (Ensembl Compara\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	ppk23	Alliance	DIOPT (Ensembl Compara\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	ppk24	Alliance	DIOPT (Ensembl Compara\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	ppk25	Alliance	DIOPT (Ensembl Compara\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	ppk3	Alliance	DIOPT (Ensembl Compara\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	delm-1	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)
Caenorhabditis elegans (roundworm):	delm-1	Alliance	DIOPT (Ensembl Compara\|OMA\|PANTHER)
Drosophila melanogaster (fruit fly):	ppk8	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	ppk8	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	ppk26	Alliance	DIOPT (InParanoid\|OMA\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	rpk	Alliance	DIOPT (InParanoid\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	ppk16	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	ppk5	Alliance	DIOPT (Ensembl Compara\|InParanoid\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	ppk5	Alliance	DIOPT (Ensembl Compara\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Nach	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Nach	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	ppk17	Alliance	DIOPT (Ensembl Compara\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	ppk21	Alliance	DIOPT (OMA\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	ppk6	Alliance	DIOPT (Ensembl Compara\|InParanoid\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	ppk6	Alliance	DIOPT (Ensembl Compara\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	asic4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	asic4	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	ppk29	Alliance	DIOPT (Ensembl Compara\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	ppk18	Alliance	DIOPT (Ensembl Compara\|PANTHER\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	84,389,610 - 84,411,545 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	9	84,390,104 - 84,411,538 (+)	Ensembl				GRCr8
mRatBN7.2	9	76,941,532 - 76,962,900 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	76,941,532 - 76,962,900 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	9	85,385,842 - 85,407,158 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	90,514,723 - 90,536,037 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	88,900,898 - 88,922,216 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	82,647,071 - 82,668,920 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	82,647,071 - 82,668,920 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	9	82,412,948 - 82,438,181 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	9	74,728,291 - 74,749,661 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	9	74,511,463 - 74,532,798 (+)	NCBI		Celera
RGSC_v3.1	9	74,875,294 - 74,896,710 (+)	NCBI
Cytogenetic Map	9	q33	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

cerebrotendinous xanthomatosis (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

2,4,4'-trichlorobiphenyl (ISO)

4,4'-sulfonyldiphenol (ISO)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

aristolochic acid A (ISO)

atrazine (EXP,ISO)

Azoxymethane (ISO)

benzo[a]pyrene (EXP,ISO)

bisphenol A (EXP)

bisphenol F (ISO)

Butylbenzyl phthalate (ISO)

C60 fullerene (EXP)

cisplatin (ISO)

Cuprizon (EXP)

dextran sulfate (ISO)

glyphosate (EXP)

hydralazine (ISO)

ketamine (EXP)

Licochalcone B (ISO)

mono(2-ethylhexyl) phthalate (ISO)

morphine (ISO)

PCB138 (ISO)

pirinixic acid (ISO)

sodium arsenite (ISO)

Theaflavin 3,3'-digallate (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

toluene (ISO)

trichloroethene (EXP)

triclosan (ISO)

valproic acid (EXP,ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

behavioral fear response (ISO)

monoatomic ion transmembrane transport (IEA)

monoatomic ion transport (IEA)

sodium ion transmembrane transport (IBA,IEA)

sodium ion transport (IEA)

Cellular Component

membrane (IEA)

plasma membrane (IBA,IEA)

Molecular Function

ligand-gated monoatomic ion channel activity (IEA)

ligand-gated sodium channel activity (IBA)

pH-gated sodium channel activity (IDA)

protein binding (ISO)

sodium channel activity (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	A new member of the acid-sensing ion channel family.	Akopian AN, etal., Neuroreport. 2000 Jul 14;11(10):2217-22. doi: 10.1097/00001756-200007140-00031.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	A new member of acid-sensing ion channels from pituitary gland.	Grunder S, etal., Neuroreport 2000 Jun 5;11(8):1607-11.
4.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
5.	GOA pipeline	RGD automated data pipeline
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:16085050	PMID:25828470

Genomics

Comparative Map Data

Asic4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	84,389,610 - 84,411,545 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	9	84,390,104 - 84,411,538 (+)	Ensembl				GRCr8
mRatBN7.2	9	76,941,532 - 76,962,900 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	76,941,532 - 76,962,900 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	9	85,385,842 - 85,407,158 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	90,514,723 - 90,536,037 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	88,900,898 - 88,922,216 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	82,647,071 - 82,668,920 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	82,647,071 - 82,668,920 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	9	82,412,948 - 82,438,181 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	9	74,728,291 - 74,749,661 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	9	74,511,463 - 74,532,798 (+)	NCBI		Celera
RGSC_v3.1	9	74,875,294 - 74,896,710 (+)	NCBI
Cytogenetic Map	9	q33	NCBI

ASIC4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	219,507,093 - 219,538,772 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	219,514,170 - 219,538,772 (+)	Ensembl			hg38	GRCh38
GRCh37	2	220,379,204 - 220,403,494 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	220,087,296 - 220,111,738 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	2	214,148,884 - 214,173,457 (+)	NCBI		Celera
Cytogenetic Map	2	q35	NCBI
HuRef	2	212,231,962 - 212,256,523 (+)	NCBI		HuRef
CHM1_1	2	220,384,734 - 220,409,316 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	219,991,838 - 220,023,471 (+)	NCBI		T2T-CHM13v2.0

Asic4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	75,426,467 - 75,450,984 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	75,427,080 - 75,450,987 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	1	75,450,510 - 75,474,340 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	75,450,436 - 75,474,343 (+)	Ensembl			mm10	GRCm38
MGSCv37	1	75,447,085 - 75,470,915 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	1	75,333,847 - 75,357,488 (+)	NCBI		MGSCv36	mm8
Celera	1	75,941,575 - 75,963,693 (+)	NCBI		Celera
Cytogenetic Map	1	C4	NCBI
cM Map	1	39.08	NCBI

Asic4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955453	13,935,826 - 13,961,664 (-)	Ensembl
ChiLan1.0	NW_004955453	13,937,745 - 13,961,664 (-)	NCBI	ChiLan1.0	ChiLan1.0

ASIC4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	13	122,142,061 - 122,168,942 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2B	122,157,383 - 122,183,950 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2B	106,770,714 - 106,796,044 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2B	225,361,131 - 225,386,087 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	225,361,477 - 225,386,081 (+)	Ensembl			panPan2	panpan1.1

ASIC4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	37	26,024,136 - 26,048,060 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	37	26,024,947 - 26,048,077 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	37	26,849,461 - 26,873,031 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	37	26,039,062 - 26,062,668 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	37	26,039,987 - 26,063,158 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	37	25,942,213 - 25,966,226 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	37	25,879,090 - 25,902,650 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	37	25,899,663 - 25,923,239 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Asic4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	175,553,612 - 175,576,041 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936569	1,896,395 - 1,918,847 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936569	1,894,631 - 1,918,822 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ASIC4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	121,522,550 - 121,547,497 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	15	121,520,003 - 121,547,520 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	134,594,197 - 134,626,509 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ASIC4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	105,406,889 - 105,433,792 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666040	93,967,447 - 93,992,202 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Asic4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624823	5,523,185 - 5,544,956 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624823	5,523,166 - 5,544,982 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Asic4
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	4	148,802,920 - 148,824,567 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Asic4
273 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	384
Count of miRNA genes:	205
Interacting mature miRNAs:	244
Transcripts:	ENSRNOT00000027135
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2303170	Bp332	Blood pressure QTL 332	3.73	0.027	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	9	6714888	84474983	Rat
631656	Bp108	Blood pressure QTL 108	5.97	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	56047863	101047863	Rat
7411571	Bw138	Body weight QTL 138	14.3	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	9	40029925	85029925	Rat
1582203	Gluco19	Glucose level QTL 19	3.3	0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	9	63376862	108376862	Rat
8662828	Vetf6	Vascular elastic tissue fragility QTL 6	3.9		artery integrity trait (VT:0010639)	patent ductus arteriosus score (CMO:0002566)	9	44458256	99506504	Rat
724515	Uae16	Urinary albumin excretion QTL 16	8		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	65657365	108376720	Rat
61352	Bp34	Blood pressure QTL 34	5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	82168823	86720295	Rat
1598834	Memor11	Memory QTL 11	2.5		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	9	44458256	85262605	Rat
70218	Cm28	Cardiac mass QTL 28	8.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	9	41720295	86720295	Rat
724544	Uae9	Urinary albumin excretion QTL 9	4.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	9	64220169	109220169	Rat
2290450	Scl57	Serum cholesterol level QTL 57	4.15		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	9	44458256	121768150	Rat
1578760	Cm53	Cardiac mass QTL 53	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	9	64220169	109220169	Rat
1581580	Uae34	Urinary albumin excretion QTL 34			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	64220169	109220169	Rat
1300134	Bp185	Blood pressure QTL 185	3.73		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	9	68875497	121768150	Rat
1354626	Bvd1	Brain ventricular dilatation QTL 1	3.73	0.001	brain ventricle morphology trait (VT:0000822)	hydrocephalus severity score (CMO:0001881)	9	83161999	118999486	Rat
731164	Uae25	Urinary albumin excretion QTL 25	3.5	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	48718864	108376862	Rat
7411656	Foco26	Food consumption QTL 26	9.8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	9	40029925	85029925	Rat
4889943	Bss90	Bone structure and strength QTL 90	4.1		tibia area (VT:1000281)	tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)	9	54506504	99506504	Rat
1578757	Pur6	Proteinuria QTL 6	3.3	0.005	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	9	64220169	109220169	Rat

Markers in Region

D9Mco53

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	76,943,526 - 76,943,723 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	82,649,066 - 82,649,262	NCBI	Rnor6.0
Rnor_5.0	9	82,418,327 - 82,418,523	UniSTS	Rnor5.0
RGSC_v3.4	9	74,730,286 - 74,730,482	UniSTS	RGSC3.4
Celera	9	74,513,458 - 74,513,654	UniSTS
Cytogenetic Map	9	q33	UniSTS

D9Mco55

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	76,962,850 - 76,963,043 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	82,668,871 - 82,669,063	NCBI	Rnor6.0
Rnor_5.0	9	82,438,132 - 82,438,324	UniSTS	Rnor5.0
RGSC_v3.4	9	74,749,612 - 74,749,804	UniSTS	RGSC3.4
Celera	9	74,532,749 - 74,532,941	UniSTS
Cytogenetic Map	9	q33	UniSTS

D9Mco54

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	9	84,398,346 - 84,398,530 (+)	Marker Load Pipeline
mRatBN7.2	9	76,949,699 - 76,949,885 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	82,655,239 - 82,655,426	NCBI	Rnor6.0
Rnor_5.0	9	82,424,500 - 82,424,687	UniSTS	Rnor5.0
RGSC_v3.4	9	74,736,459 - 74,736,646	UniSTS	RGSC3.4
Celera	9	74,519,634 - 74,519,816	UniSTS
Cytogenetic Map	9	q33	UniSTS

stSG633055

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	76,941,889 - 76,943,117 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	82,647,429 - 82,648,656	NCBI	Rnor6.0
Rnor_5.0	9	82,416,690 - 82,417,917	UniSTS	Rnor5.0
RGSC_v3.4	9	74,728,649 - 74,729,876	UniSTS	RGSC3.4
Celera	9	74,511,821 - 74,513,048	UniSTS
Cytogenetic Map	9	q33	UniSTS

ECD06448

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	76,942,410 - 76,943,117 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	82,647,950 - 82,648,656	NCBI	Rnor6.0
Rnor_5.0	9	82,417,211 - 82,417,917	UniSTS	Rnor5.0
RGSC_v3.4	9	74,729,170 - 74,729,876	UniSTS	RGSC3.4
Celera	9	74,512,342 - 74,513,048	UniSTS
Cytogenetic Map	9	q33	UniSTS

REN53167

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	76,941,863 - 76,942,133 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	82,647,403 - 82,647,672	NCBI	Rnor6.0
Rnor_5.0	9	82,416,664 - 82,416,933	UniSTS	Rnor5.0
RGSC_v3.4	9	74,728,623 - 74,728,892	UniSTS	RGSC3.4
Celera	9	74,511,795 - 74,512,064	UniSTS
Cytogenetic Map	9	q33	UniSTS

REN53166

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	76,941,659 - 76,941,910 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	82,647,199 - 82,647,449	NCBI	Rnor6.0
Rnor_5.0	9	82,416,460 - 82,416,710	UniSTS	Rnor5.0
RGSC_v3.4	9	74,728,419 - 74,728,669	UniSTS	RGSC3.4
Celera	9	74,511,591 - 74,511,841	UniSTS
Cytogenetic Map	9	q33	UniSTS

REN53165

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	76,941,410 - 76,941,679 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	82,646,950 - 82,647,218	NCBI	Rnor6.0
Rnor_5.0	9	82,416,211 - 82,416,479	UniSTS	Rnor5.0
RGSC_v3.4	9	74,728,170 - 74,728,438	UniSTS	RGSC3.4
Celera	9	74,511,342 - 74,511,610	UniSTS
Cytogenetic Map	9	q33	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
14	8	57	147	75	74	43	72	43	6	285	160	11	122	63	87	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_022234	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063267669	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC112361	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AJ242554	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AJ271642	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CB703338	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000027135 ⟹ ENSRNOP00000027135

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	9	84,390,104 - 84,411,538 (+)	Ensembl
mRatBN7.2 Ensembl	9	76,941,532 - 76,962,900 (+)	Ensembl
Rnor_6.0 Ensembl	9	82,647,071 - 82,668,920 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000101375 ⟹ ENSRNOP00000094476

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	9	84,390,104 - 84,411,538 (+)	Ensembl
mRatBN7.2 Ensembl	9	76,941,532 - 76,962,900 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000102212 ⟹ ENSRNOP00000081247

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	9	84,390,104 - 84,411,538 (+)	Ensembl
mRatBN7.2 Ensembl	9	76,941,532 - 76,962,900 (+)	Ensembl

RefSeq Acc Id:

NM_022234 ⟹ NP_071570

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	84,390,177 - 84,411,545 (+)	NCBI
mRatBN7.2	9	76,941,532 - 76,962,900 (+)	NCBI
Rnor_6.0	9	82,647,071 - 82,668,920 (+)	NCBI
Rnor_5.0	9	82,412,948 - 82,438,181 (+)	NCBI
RGSC_v3.4	9	74,728,291 - 74,749,661 (+)	RGD
Celera	9	74,511,463 - 74,532,798 (+)	RGD

Sequence:

show sequence

CGCAGGGACACACGCAGGGGCTGACAGCTGTGCGGGTGCTGATAAGGGAAGCCACAAGGAGACG
ATCGAGGAGAGAGACAAGCGGCAGCAGAGGCAGCAGCGACAGAGGCAGCGCCGGGGCTGCGGAG
CTGCTGGGAGTGGGAGTGACGCCCCCACCTCGGGCCCCCACCCTGTCCCCATCCTCCTCCTGGT
TGCCCTGAGTTTAGAAGAGCAGCCGCTGCCACCACCACCACTCCGGAGGGCACCAGGGCTGCTG
TCCAGGGAAGGACAGTAGCAGTGAGGCTCTGGCCAGTCCCAGCAGCCGGGGACAGATGCCGATC
GAGATTGTGTGCAAAATCAAATTTGCTGAGGAGGATGCAAAACCCAAGGAGAAGGAGGCAGGGG
ATGAGCAGAGCCTCCTGGGGGCTGCTCAGGGGCCAGCAGCCCCTCGGGACCTGGCTACCTTTGC
CAGCACCAGTACTCTGCATGGGCTGGGCCGGGCCTGTGGCCCAGGCCCCCATGGACTGCGCAGA
ACCCTGTGGGTACTGGCCCTACTCACCTCACTGGCTGCCTTCCTGTACCAGGCAGCCAGCCTGG
CCAGGGGCTACCTGACCCGGCCTCACCTGGTAGCCATGGACCCTGCTGCCCCAGCCCCAGTGGC
GGGCTTTCCGGCTGTCACCCTCTGCAACATCAACCGCTTCCGGCATTCGGCACTCAGCGATGCT
GATATCTTCCACCTGGCCAATCTGACAGGGCTGCCCCCCAAAGACCGGGATGGGCACCGTGCAG
CTGGCCTTCGCTACCCAGAGCCTGACATGGTAGACATCCTCAACCGCACTGGCCACCAGCTTGC
TGACATGCTCAAGAGCTGCAACTTCAGTGGGCACCACTGCTCCGCCAGCAACTTCTCTGTGGTC
TATACTCGCTATGGAAAGTGTTACACCTTCAATGCAGATCCTCAGAGTTCACTGCCCAGCAGGG
CAGGCGGCATGGGTAGTGGCCTGGAGATCATGCTAGACATCCAGCAGGAGGAATACCTACCCAT
ATGGAGGGAGACAAATGAGACATCATTCGAGGCAGGGATCCGGGTGCAGATCCACAGCCAGGAG
GAGCCTCCCTACATCCACCAGCTGGGGTTCGGTGTGTCCCCAGGCTTCCAGACTTTTGTGTCCT
GCCAGGAACAGCGGCTAACTTATCTGCCCCAGCCTTGGGGCAACTGCCGGGCGGAAAGCAAGCT
CAGGGAGCCTGAGCTTCAGGGCTACTCAGCCTATAGTGTGTCTGCCTGCCGACTGCGCTGTGAG
AAGGAGGCCGTGCTTCAGCGCTGCCACTGCCGGATGGTGCACATGCCAGGCAATGAGACCATCT
GCCCGCCAAATATCTACATTGAATGTGCCGACCACACACTGGACTCCCTGGGTGGGGGCTCTGA
GGGCCCATGCTTCTGCCCTACACCCTGCAACCTGACTCGTTACGGCAAAGAGATCTCCATGGTC
AAGATCCCCAACAGGGGCTCTGCCAGGTACCTGGCGAGGAAGTACAACCGCAATGAGACCTACA
TAAGGGAAAACTTCTTGGTCCTGGATGTCTTCTTTGAGGCCCTAACCTCTGAAGCCATGGAACA
GCGAGCTGCCTATGGTCTGTCAGCCTTGCTGGGGGACCTTGGGGGACAGATGGGCCTGTTCATT
GGGGCTAGCATCCTCACCTTGCTGGAGATCCTTGACTACATCTATGAGGTCTCCTGGGATCGAC
TCAAGAGGGTGTGGCGACGGCCCAAGACCCCACTTAGGACGTCCACTGGGGGCATCTCCACTTT
GGGGCTGCAGGAACTGAAGGAACAGAGTCCCTGTCCAAATCGAGGCCGTGCTGAGGGTGGTGGG
GCTAGCAACCTGCTTCCCAACCATCACCACCCCCACGGCCCCCCAGGAAGCCTCTTTGAAGACT
TTGCTTGCTAGGATGGTGCTGTGTGGGGAAAGTACCCATGAAACCCCACACATCTCCTATTCCT
GGGACAGAAGGTCTGGGGCAGCCCAGGGCTAAGGGAAGGGGTGGTGCTCACTGAGAGGCCAGGA
CTAGGGTCCTGCTCTCCCTGACCTAGGCTCAGCTGCCTTGCACAAGAGTCCTTCTTGTCCATAC
TCCCTGCTCCCAGGCAGGTGTCCAGGAAGGGCTAGAGACCGGACTAGAGGCCCCTGAGGAGGGG
AGGGAGGAAGAGAGGGAGGAAGGCGGAACCCTGGTAGAGCCCCTCTGTACATTTGTATATATTT
AGGGACTGGGTGGGGGTGGGACACAGACATAGAAGGGTGGGGCTGCAGGGGAGGGTGACACAGG
ATAGTCAGGGTCCCAACCCTAATGGCAGAAGGCAACTCCTTGGGACCTAGGCATGTTGGGCTGG
TTCTACTTCCCTCTTTCCAGGCCCAGCTCCCTCTTGGCAGGGGGAGTGGGTGGCCCAGCAGGCC
TGGCCCAGCTCCCAGTTCCCCCTGTACCAGCCCCACCACAAGTTCCCTTCGTGGGGAGTGGGTG
GAAAGACCTTTCAGACCTTGGCTAAGCTTAGGGGGAGAGGGAGTGGCCTTCTCAGGCCTTGCTC
CCTAGAGACTGGTTTTATAAAGTGCTGGTGAACTTGGGAATAAAGAGACACAAAGAATTCTGTG
TCTG

hide sequence

RefSeq Acc Id:

XM_063267669 ⟹ XP_063123739

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	84,389,610 - 84,411,534 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_071570	(Get FASTA)	NCBI Sequence Viewer
	XP_063123739	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	CAB61836	(Get FASTA)	NCBI Sequence Viewer
	CAB93984	(Get FASTA)	NCBI Sequence Viewer
	EDL75443	(Get FASTA)	NCBI Sequence Viewer
	EDL75444	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000027135
GenBank Protein	Q9JHS6	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_071570 ⟸ NM_022234

- UniProtKB:

Q9QYV9 (UniProtKB/Swiss-Prot), Q9JHS6 (UniProtKB/Swiss-Prot), G3V8N2 (UniProtKB/TrEMBL), A6JW35 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPIEIVCKIKFAEEDAKPKEKEAGDEQSLLGAAQGPAAPRDLATFASTSTLHGLGRACGPGPHG
LRRTLWVLALLTSLAAFLYQAASLARGYLTRPHLVAMDPAAPAPVAGFPAVTLCNINRFRHSAL
SDADIFHLANLTGLPPKDRDGHRAAGLRYPEPDMVDILNRTGHQLADMLKSCNFSGHHCSASNF
SVVYTRYGKCYTFNADPQSSLPSRAGGMGSGLEIMLDIQQEEYLPIWRETNETSFEAGIRVQIH
SQEEPPYIHQLGFGVSPGFQTFVSCQEQRLTYLPQPWGNCRAESKLREPELQGYSAYSVSACRL
RCEKEAVLQRCHCRMVHMPGNETICPPNIYIECADHTLDSLGGGSEGPCFCPTPCNLTRYGKEI
SMVKIPNRGSARYLARKYNRNETYIRENFLVLDVFFEALTSEAMEQRAAYGLSALLGDLGGQMG
LFIGASILTLLEILDYIYEVSWDRLKRVWRRPKTPLRTSTGGISTLGLQELKEQSPCPNRGRAE
GGGASNLLPNHHHPHGPPGSLFEDFAC

hide sequence

Ensembl Acc Id:

ENSRNOP00000027135 ⟸ ENSRNOT00000027135

Ensembl Acc Id:

ENSRNOP00000081247 ⟸ ENSRNOT00000102212

Ensembl Acc Id:

ENSRNOP00000094476 ⟸ ENSRNOT00000101375

RefSeq Acc Id:	XP_063123739 ⟸ XM_063267669
- Peptide Label:	isoform X1
- UniProtKB:	Q9QYV9 (UniProtKB/Swiss-Prot), Q9JHS6 (UniProtKB/Swiss-Prot), A6JW35 (UniProtKB/TrEMBL), G3V8N2 (UniProtKB/TrEMBL)

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9JHS6-F1-model_v2	AlphaFold	Q9JHS6	1-539	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:621068	AgrOrtholog
BioCyc Gene	G2FUF-27066	BioCyc
Ensembl Genes	ENSRNOG00000019985	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000027135	ENTREZGENE
Gene3D-CATH	Acid-sensing ion channels like domains	UniProtKB/Swiss-Prot
	YojJ-like	UniProtKB/Swiss-Prot
InterPro	ENaC	UniProtKB/Swiss-Prot
	ENaC_CS	UniProtKB/Swiss-Prot
KEGG Report	rno:63882	UniProtKB/Swiss-Prot
NCBI Gene	63882	ENTREZGENE
PANTHER	ACID-SENSING ION CHANNEL 4	UniProtKB/Swiss-Prot
	PTHR11690	UniProtKB/Swiss-Prot
Pfam	ASC	UniProtKB/Swiss-Prot
PhenoGen	Asic4	PhenoGen
PRINTS	AMINACHANNEL	UniProtKB/Swiss-Prot
PROSITE	ASC	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000019985	RatGTEx
UniProt	A0A8I5ZSF3_RAT	UniProtKB/TrEMBL
	A0A8I6AKV8_RAT	UniProtKB/TrEMBL
	A6JW35	ENTREZGENE, UniProtKB/TrEMBL
	ASIC4_RAT	UniProtKB/Swiss-Prot
	G3V8N2	ENTREZGENE, UniProtKB/TrEMBL
	Q9JHS6	ENTREZGENE
	Q9QYV9	ENTREZGENE
UniProt Secondary	Q9QYV9	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-12-13	Asic4	acid sensing ion channel subunit family member 4	Asic4	acid sensing ion channel 4	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2015-12-09	Asic4	acid sensing ion channel 4	Asic4	acid-sensing (proton-gated) ion channel family member 4	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2012-07-13	Asic4	acid-sensing (proton-gated) ion channel family member 4	Accn4	amiloride-sensitive cation channel 4, pituitary	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-09-10	Accn4	amiloride-sensitive cation channel 4, pituitary	Asic4	SPASIC protein	Symbol and Name updated	1299863	APPROVED
2002-08-07	Asic4	SPASIC protein			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_expression	strongest expression in pituitary gland; also expressed in throughout brain, in the spinal cord, and inner ear	632227

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar