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Gene: Ltb4r2 (leukotriene B4 receptor 2) Rattus norvegicus

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Symbol:

Ltb4r2

Name:

leukotriene B4 receptor 2

RGD ID:

621029

Description:

Predicted to enable G protein-coupled peptide receptor activity and leukotriene B4 receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to act upstream of or within keratinocyte migration and signal transduction. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human LTB4R2 (leukotriene B4 receptor 2); PARTICIPATES IN calcium/calcium-mediated signaling pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; ammonium chloride; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LTB4 receptor JULF2; LTB4-R 2; LTB4-R2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	LTB4R2 (leukotriene B4 receptor 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Ltb4r2 (leukotriene B4 receptor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ltb4r2 (leukotriene B4 receptor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	LTB4R2 (leukotriene B4 receptor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ltb4r2 (leukotriene B4 receptor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	LTB4R2 (leukotriene B4 receptor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	LTB4R2 (leukotriene B4 receptor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ltb4r2 (leukotriene B4 receptor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Ltb4r2 (leukotriene B4 receptor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	CIDEB (cell death inducing DFFA like effector b)	HGNC	PhylomeDB
Alliance orthologs ³
Mus musculus (house mouse):	Ltb4r2 (leukotriene B4 receptor 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	LTB4R2 (leukotriene B4 receptor 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ltb4r2b (leukotriene B4 receptor 2b)	Alliance	DIOPT (Hieranoid\|OrthoFinder\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	ltb4r2a (leukotriene B4 receptor 2a)	Alliance	DIOPT (Hieranoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	ltb4r2a (leukotriene B4 receptor 2a)	Alliance	DIOPT (InParanoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	ltb4r2	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	ltb4r2	Alliance	DIOPT (InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	33,228,634 - 33,230,453 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	15	33,228,634 - 33,230,453 (+)	Ensembl				GRCr8
mRatBN7.2	15	29,258,712 - 29,260,531 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	29,259,240 - 29,260,316 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	15	31,104,925 - 31,106,001 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	32,252,131 - 32,253,207 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	30,494,484 - 30,495,560 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	34,446,478 - 34,448,220 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	34,446,878 - 34,447,954 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	15	38,335,390 - 38,336,466 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	15	33,923,472 - 33,924,548 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	15	28,833,900 - 28,834,976 (+)	NCBI		Celera
RGSC_v3.1	15	33,939,171 - 33,940,248 (+)	NCBI
Cytogenetic Map	15	p13	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Acute Lung Injury (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (EXP,ISO)

3,3',4,4',5-pentachlorobiphenyl (ISO)

4,4'-sulfonyldiphenol (ISO)

ammonium chloride (EXP)

aristolochic acid A (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (EXP)

capsaicin (EXP)

choline (ISO)

copper atom (EXP)

copper(0) (EXP)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

cypermethrin (ISO)

decabromodiphenyl ether (EXP)

Dibutyl phosphate (ISO)

dimethylarsinic acid (ISO)

ethanol (ISO)

flavonoids (EXP)

folic acid (ISO)

L-methionine (ISO)

leukotriene B4 (ISO)

leukotriene B5 (ISO)

mancozeb (ISO)

methylarsonic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (ISO)

pyridaben (ISO)

resveratrol (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

tetrachloromethane (ISO)

titanium dioxide (ISO)

trichloroethene (EXP)

triphenyl phosphate (ISO)

triptonide (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

G protein-coupled receptor signaling pathway (IEA)

keratinocyte migration (ISO)

leukotriene signaling pathway (IEA)

neuropeptide signaling pathway (IBA)

signal transduction (IEA,ISO)

Cellular Component

membrane (IEA,ISO)

plasma membrane (IBA,IEA,ISO)

Molecular Function

G protein-coupled peptide receptor activity (IBA)

G protein-coupled receptor activity (IEA)

leukotriene B4 receptor activity (IBA,IEA,ISO)

leukotriene receptor activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

calcium/calcium-mediated signaling pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
3.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
4.	GOA pipeline	RGD automated data pipeline
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:10889186	PMID:15866883	PMID:19946888	PMID:21189570

Genomics

Comparative Map Data

Ltb4r2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	33,228,634 - 33,230,453 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	15	33,228,634 - 33,230,453 (+)	Ensembl				GRCr8
mRatBN7.2	15	29,258,712 - 29,260,531 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	29,259,240 - 29,260,316 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	15	31,104,925 - 31,106,001 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	32,252,131 - 32,253,207 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	30,494,484 - 30,495,560 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	34,446,478 - 34,448,220 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	34,446,878 - 34,447,954 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	15	38,335,390 - 38,336,466 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	15	33,923,472 - 33,924,548 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	15	28,833,900 - 28,834,976 (+)	NCBI		Celera
RGSC_v3.1	15	33,939,171 - 33,940,248 (+)	NCBI
Cytogenetic Map	15	p13	NCBI

LTB4R2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	24,310,140 - 24,312,038 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	24,305,734 - 24,312,053 (+)	Ensembl			hg38	GRCh38
GRCh37	14	24,779,346 - 24,781,244 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	23,848,001 - 23,850,798 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	14	23,848,000 - 23,850,798	NCBI
Celera	14	4,643,986 - 4,645,888 (+)	NCBI		Celera
Cytogenetic Map	14	q12	NCBI
HuRef	14	4,894,524 - 4,896,426 (+)	NCBI		HuRef
CHM1_1	14	24,777,957 - 24,779,859 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	14	18,508,483 - 18,510,381 (+)	NCBI		T2T-CHM13v2.0

Ltb4r2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	55,995,379 - 56,001,523 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	55,998,885 - 56,002,595 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	14	55,757,922 - 55,764,066 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	55,761,428 - 55,765,138 (+)	Ensembl			mm10	GRCm38
MGSCv37	14	56,380,761 - 56,381,843 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	14	54,715,995 - 54,717,077 (+)	NCBI		MGSCv36	mm8
Celera	14	53,566,960 - 53,568,042 (+)	NCBI		Celera
Cytogenetic Map	14	C3	NCBI
cM Map	14	28.19	NCBI

Ltb4r2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955409	35,989,425 - 35,991,492 (-)	Ensembl
ChiLan1.0	NW_004955409	35,989,425 - 35,991,492 (-)	NCBI	ChiLan1.0	ChiLan1.0

LTB4R2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	4,278,047 - 4,282,326 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	8	4,280,869 - 4,281,948 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	4,199,538 - 4,206,302 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	4,388,676 - 4,392,789 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	8	4,391,671 - 4,392,750 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	8	4,079,024 - 4,083,137 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	4,140,847 - 4,144,961 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	4,403,431 - 4,407,545 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Ltb4r2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	36,146,927 - 36,149,192 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936722	239,811 - 242,050 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LTB4R2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	74,978,876 - 74,983,768 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	7	74,978,871 - 74,983,811 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	80,249,814 - 80,254,577 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LTB4R2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	1,292,283 - 1,298,723 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	24	1,293,587 - 1,294,756 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666036	12,976,846 - 12,979,595 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ltb4r2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624820	8,192,441 - 8,196,375 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624820	8,192,441 - 8,196,472 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Ltb4r2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	12	69,241,331 - 69,242,407 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Ltb4r2
5 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	170
Count of miRNA genes:	127
Interacting mature miRNAs:	137
Transcripts:	ENSRNOT00000027619
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1641913	Colcr2	Colorectal carcinoma resistance QTL 2	6.57	0.0197	intestine integrity trait (VT:0010554)	poorly differentiated malignant colorectal tumor number (CMO:0002076)	15	2315759	47315759	Rat
5684946	Bss98	Bone structure and strength QTL 98	3.9	0.0026	tibia strength trait (VT:1000284)	tibia ultimate force (CMO:0001734)	15	1	39411584	Rat
1641887	Alcrsp14	Alcohol response QTL 14			response to alcohol trait (VT:0010489)	brain neurotensin receptor 1 density (CMO:0002068)	15	1	44836456	Rat
738017	Hcas7	Hepatocarcinoma susceptibility QTL 7	2.91		liver integrity trait (VT:0010547)	liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)	15	2315759	53331089	Rat
152025253	Hrtrt24	Heart rate QTL 24	3.82		heart pumping trait (VT:2000009)		15	31855803	92671517	Rat
10054130	Srcrt8	Stress Responsive Cort QTL 8	2.18	0.0085	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	15	28527732	73527732	Rat
10755503	Bp391	Blood pressure QTL 391	2.37		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	15	22728353	42072050	Rat
1578646	Bmd18	Bone mineral density QTL 18	5.2		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	15	25285835	104695021	Rat
2324620	Coatc3	Coat color QTL 3			coat/hair pigmentation trait (VT:0010463)	pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)	15	22336351	52597086	Rat
1578647	Bmd17	Bone mineral density QTL 17	4		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	15	25285835	104695021	Rat
61424	Scl1	Serum cholesterol level QTL 1	7.7	0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	15	19155762	87086765	Rat
10401805	Kidm51	Kidney mass QTL 51			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	15	2785923	47785923	Rat
2317750	Glom26	Glomerulus QTL 26	4.3		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	15	14926594	71614418	Rat
631550	Bw7	Body weight QTL 7	3.6		body mass (VT:0001259)	body weight (CMO:0000012)	15	22336351	67336351	Rat
1578660	Bss19	Bone structure and strength QTL 19	4.3		femur morphology trait (VT:0000559)	bone trabecular cross-sectional area (CMO:0002311)	15	25285835	104695021	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
7	4	28	74	32	35	9	39	9	6	133	85	3	54	29	45	26	9	9

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_053640	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB052660	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC116083	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474049	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000027619 ⟹ ENSRNOP00000027619

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	15	33,228,634 - 33,230,453 (+)	Ensembl
mRatBN7.2 Ensembl	15	29,259,240 - 29,260,316 (+)	Ensembl
Rnor_6.0 Ensembl	15	34,446,878 - 34,447,954 (+)	Ensembl

RefSeq Acc Id:

NM_053640 ⟹ NP_446092

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	33,228,634 - 33,230,453 (+)	NCBI
mRatBN7.2	15	29,258,712 - 29,260,531 (+)	NCBI
Rnor_6.0	15	34,446,878 - 34,447,954 (+)	NCBI
Rnor_5.0	15	38,335,390 - 38,336,466 (+)	NCBI
RGSC_v3.4	15	33,923,472 - 33,924,548 (+)	RGD
Celera	15	28,833,900 - 28,834,976 (+)	RGD

Sequence:

show sequence

ATGTCTGTCTGCTACCGTCCGCCTGGGAATGAGACGCTGCTGAGTTGGAAGGGCTCGCGGGCCA
CCGGCACTGCCTTTCTCCTGCTGGCGGCGTTGCTGGGACTGCCAGGCAATGGCTTCGTAGTGTG
GAGCTTGGCGGGCTGGCGGCCCACCGCCGGGCGGCCACTAGCAGCCACACTTGTGCTGCATCTG
GCGCTAGCCGACGGCGCGGTGCTGCTGCTCACGCCGCTCTTTGTGGCCTTCCTGAGCCGACAGG
CTTGGCCCCTGGGCCAGGTGGGCTGCAAGGCAGTGTACTACGTGTGCGCGCTCAGCATGTACGC
CAGCGTGCTGCTCACCGGCCTGCTCAGCCTGCAGCGCTGTCTAGCGGTCACTCGGCCTTTCCTG
GCTCCCCGACTTCGCAGCCCGGCCCTGGCCCGCCGCCTGCTGCTGGGGGTCTGGCTGGCCGCCC
TGGTGCTCGCCGTCCCGGCCGCGGTCTACCGCCACCTCTGGGGTGATCGCGTGTGTCAATTGTG
CCACCCATCGGCCGTGCACGCTGCAGCTCATCTGAGCCTGGAGACCCTGACTGCCTTCGTCCTG
CCTTTTGGGACCGTGCTCGGCTGCTACGGCGTGACGCTGGCGCGGTTGCGGGGAGCGCGCTGGG
GCTCGGGGCGACAAGGCACGCGGGTGGGTCGTCTGGTGAGCGCCATCGTACTGGCCTTTGGCTT
GCTCTGGGCCCCCTACCACGCGGTCAATCTCCTACAGGCGGTGGCCGCGCTCGCTCCGCCGGAA
GGACCCCTAGCCAGGCTCGGTGGGGCGGGCCAGGCAGCGCGCGCTGGAACTACAGCCTTGGCTT
TCTTTAGTTCCAGCGTCAACCCGGTGCTCTACGTCTTTACTGCGGGTGATTTGCTGCCGCGGGC
GGGGCCTCGGTTCCTCACTCGACTCTTCGAAGGCTCTGGGGAGGCCCGAGTAGGCAGCCGCTCT
AGGGAGGGTACCATGGAGCTCCGAACTACCCCCAGGCTGAAAGTAGTGGGTCAGGGCAGGGGCT
ATGGAGACCCTGGAGGTGGGGGCAGGATGGAGAAAGACAGTCAGGAATGGTAG

hide sequence

Protein Sequences


Protein RefSeqs	NP_446092	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	BAB60815	(Get FASTA)	NCBI Sequence Viewer
	EDM14280	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000027619
	ENSRNOP00000027619.1
GenBank Protein	Q924U0	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_446092 ⟸ NM_053640

- UniProtKB:

Q924U0 (UniProtKB/Swiss-Prot), A6KH51 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSVCYRPPGNETLLSWKGSRATGTAFLLLAALLGLPGNGFVVWSLAGWRPTAGRPLAATLVLHL
ALADGAVLLLTPLFVAFLSRQAWPLGQVGCKAVYYVCALSMYASVLLTGLLSLQRCLAVTRPFL
APRLRSPALARRLLLGVWLAALVLAVPAAVYRHLWGDRVCQLCHPSAVHAAAHLSLETLTAFVL
PFGTVLGCYGVTLARLRGARWGSGRQGTRVGRLVSAIVLAFGLLWAPYHAVNLLQAVAALAPPE
GPLARLGGAGQAARAGTTALAFFSSSVNPVLYVFTAGDLLPRAGPRFLTRLFEGSGEARVGSRS
REGTMELRTTPRLKVVGQGRGYGDPGGGGRMEKDSQEW

hide sequence

Ensembl Acc Id:

ENSRNOP00000027619 ⟸ ENSRNOT00000027619

Protein Domains

G-protein coupled receptors family 1 profile

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q924U0-F1-model_v2	AlphaFold	Q924U0	1-358	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:621029	AgrOrtholog
BioCyc Gene	G2FUF-13690	BioCyc
Ensembl Genes	ENSRNOG00000020382	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000027619	ENTREZGENE
	ENSRNOT00000027619.3	UniProtKB/Swiss-Prot
Gene3D-CATH	Rhodopsin 7-helix transmembrane proteins	UniProtKB/Swiss-Prot
InterPro	GPCR_Rhodpsn	UniProtKB/Swiss-Prot
	GPCR_Rhodpsn_7TM	UniProtKB/Swiss-Prot
	Leukotriene_B4_rcpt	UniProtKB/Swiss-Prot
	Leukotriene_B4_typ-2_rcpt	UniProtKB/Swiss-Prot
KEGG Report	rno:114098	UniProtKB/Swiss-Prot
NCBI Gene	114098	ENTREZGENE
PANTHER	G-PROTEIN COUPLED RECEPTOR	UniProtKB/Swiss-Prot
	LEUKOTRIENE B4 RECEPTOR 2	UniProtKB/Swiss-Prot
Pfam	7tm_1	UniProtKB/Swiss-Prot
PhenoGen	Ltb4r2	PhenoGen
PRINTS	GPCRRHODOPSN	UniProtKB/Swiss-Prot
	LTB2RECEPTOR	UniProtKB/Swiss-Prot
	LTBRECEPTOR	UniProtKB/Swiss-Prot
PROSITE	G_PROTEIN_RECEP_F1_2	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000020382	RatGTEx
Superfamily-SCOP	Family A G protein-coupled receptor-like	UniProtKB/Swiss-Prot
UniProt	A6KH51	ENTREZGENE, UniProtKB/TrEMBL
	LT4R2_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2004-09-10	Ltb4r2	leukotriene B4 receptor 2			Symbol and Name status set to approved	1299863	APPROVED
2002-08-07	Ltb4r2	leukotriene B4 receptor 2			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Annotations - KEGG (archival)