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Gene: Ntm (neurotrimin) Rattus norvegicus

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Symbol:

Ntm

Name:

neurotrimin

RGD ID:

620958

Description:

Enables identical protein binding activity. Involved in several processes, including cellular response to estradiol stimulus; negative regulation of glial cell proliferation; and regulation of neuron projection development. Located in several cellular components, including cell surface; excitatory synapse; and perinuclear region of cytoplasm. Is active in hippocampal mossy fiber to CA3 synapse; postsynaptic density membrane; and presynaptic active zone membrane. Human ortholog(s) of this gene implicated in hypertension and primary open angle glaucoma. Orthologous to human NTM (neurotrimin); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-Tetrachlorodibenzofuran; acrylamide.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

GP65; Hnt; protein CEPU-1; RNU16845

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	NTM (neurotrimin)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Ntm (neurotrimin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ntm (neurotrimin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	NTM (neurotrimin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	NTM (neurotrimin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ntm (neurotrimin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	NTM (neurotrimin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	NTM (neurotrimin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ntm (neurotrimin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Ntm (neurotrimin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	OPCML (opioid binding protein/cell adhesion molecule like)	HGNC	OrthoDB
Alliance orthologs ³
Mus musculus (house mouse):	Ntm (neurotrimin)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	NTM (neurotrimin)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	opcml (opioid binding protein/cell adhesion molecule-like)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Ama	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	Ama	Alliance	DIOPT (Ensembl Compara\|OMA\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	rig-5	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoInspector\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG31814	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoInspector\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG45781	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoInspector\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG45781	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoInspector\|SonicParanoid)
Drosophila melanogaster (fruit fly):	DIP-alpha	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoInspector\|SonicParanoid)
Drosophila melanogaster (fruit fly):	DIP-beta	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoInspector\|SonicParanoid)
Drosophila melanogaster (fruit fly):	DIP-epsilon	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoInspector\|SonicParanoid)
Drosophila melanogaster (fruit fly):	DIP-eta	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|SonicParanoid)
Drosophila melanogaster (fruit fly):	DIP-gamma	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|SonicParanoid)
Drosophila melanogaster (fruit fly):	DIP-iota	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|SonicParanoid)
Drosophila melanogaster (fruit fly):	DIP-theta	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoInspector\|SonicParanoid)
Drosophila melanogaster (fruit fly):	DIP-zeta	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoInspector\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	ntm	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	ntm	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Allele / Splice:

Ntm^{Tn(sb-T2/Bart3)2.130Mcwi}

Genetic Models:

F344-Ntm^{Tn(sb-T2/Bart3)2.130Mcwi}

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	35,634,929 - 36,625,081 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	8	35,635,640 - 36,624,807 (-)	Ensembl				GRCr8
mRatBN7.2	8	27,376,582 - 28,366,604 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	27,377,773 - 28,366,595 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	8	31,432,377 - 31,859,793 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	29,726,707 - 30,154,131 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	27,606,506 - 28,040,870 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	30,039,332 - 31,041,755 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	30,039,408 - 30,222,036 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	8	30,073,163 - 31,070,882 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	8	28,587,019 - 29,019,888 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	8	28,861,001 - 29,285,304 (-)	NCBI		Celera
RGSC_v3.1	8	28,587,115 - 29,019,985 (-)	NCBI
Cytogenetic Map	8	q13	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

congestive heart failure (ISO)

connective tissue disease (ISO)

hypertension (ISO)

Hypertriglyceridemia (ISO)

ovary epithelial cancer (ISO)

primary open angle glaucoma (ISO)

uterine fibroid (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

1,2-dichloroethane (ISO)

1-naphthyl isothiocyanate (EXP)

17beta-estradiol (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

2,4,4'-trichlorobiphenyl (ISO)

2,4-D (ISO)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

acrylamide (EXP)

aflatoxin B1 (ISO)

aldehydo-D-glucose (ISO)

all-trans-retinoic acid (ISO)

antirheumatic drug (ISO)

aripiprazole (EXP)

arsane (ISO)

arsenic atom (ISO)

atrazine (EXP)

benzo[a]pyrene (ISO)

bis(2-chloroethyl) sulfide (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

Butylbenzyl phthalate (ISO)

C60 fullerene (EXP)

cadmium atom (ISO)

cadmium dichloride (EXP,ISO)

CGP 52608 (ISO)

cytarabine (ISO)

D-glucose (ISO)

dexamethasone (ISO)

dimethylarsinic acid (EXP)

dorsomorphin (ISO)

doxorubicin (ISO)

ethanol (EXP,ISO)

ethyl methanesulfonate (ISO)

formaldehyde (ISO)

fructose (ISO)

fucoxanthin (ISO)

fulvestrant (ISO)

glucose (ISO)

glyphosate (EXP)

lipopolysaccharide (ISO)

manganese(II) chloride (EXP)

methoxychlor (EXP)

methyl methanesulfonate (ISO)

mono(2-ethylhexyl) phthalate (ISO)

N-methyl-N-nitrosourea (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

PCB138 (ISO)

PD 0325901 (ISO)

perfluorooctane-1-sulfonic acid (ISO)

phenobarbital (ISO)

potassium dichromate (ISO)

progesterone (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

senecionine (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

temozolomide (ISO)

tetrachloromethane (ISO)

titanium dioxide (ISO)

trichostatin A (ISO)

triclosan (ISO)

valproic acid (ISO)

vinclozolin (EXP)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell adhesion (IEA)

cellular response to estradiol stimulus (IEP)

cerebellum development (IEP)

heterophilic cell-cell adhesion (IBA)

negative regulation of glial cell proliferation (IDA,IEA)

negative regulation of neuron projection development (IDA)

positive regulation of neuron projection development (IDA)

positive regulation of Schwann cell migration (IMP)

regulation of synapse assembly (IBA)

response to estradiol (IEP)

Cellular Component

axon (IDA)

cell surface (IDA)

excitatory synapse (IDA)

extracellular space (IDA)

hippocampal mossy fiber to CA3 synapse (IDA)

perinuclear region of cytoplasm (IDA)

plasma membrane (IBA,IEA)

postsynaptic density membrane (IBA,IDA)

presynaptic active zone membrane (IBA,IDA)

side of membrane (IEA)

synapse (IEA)

Molecular Function

identical protein binding (IDA)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Identification of novel biomarkers in plasma for prediction of treatment response in patients with heart failure.	Cao TH, etal., Lancet. 2015 Feb 26;385 Suppl 1:S26. doi: 10.1016/S0140-6736(15)60341-5.
2.	Neurotrimin expression during cerebellar development suggests roles in axon fasciculation and synaptogenesis.	Chen S, etal., J Neurocytol. 2001 Nov;30(11):927-37.
3.	Complementary expression and heterophilic interactions between IgLON family members neurotrimin and LAMP.	Gil OD, etal., J Neurobiol. 2002 Jun 5;51(3):190-204.
4.	Neurotrimin mediates bifunctional effects on neurite outgrowth via homophilic and heterophilic interactions.	Gil OD, etal., J Neurosci. 1998 Nov 15;18(22):9312-25. doi: 10.1523/JNEUROSCI.18-22-09312.1998.
5.	Glycosylation analysis of IgLON family proteins in rat brain by liquid chromatography and multiple-stage mass spectrometry.	Itoh S, etal., Biochemistry. 2008 Sep 23;47(38):10132-54. Epub 2008 Aug 26.
6.	Neurotrimin is an estrogen-regulated determinant of peripheral sympathetic innervation.	Krizsan-Agbas D, etal., J Neurosci Res. 2008 Nov 1;86(14):3086-95.
7.	Genome-wide linkage and positional association analyses identify associations of novel AFF3 and NTM genes with triglycerides: the GenSalt study.	Li C, etal., J Genet Genomics. 2015 Mar 20;42(3):107-17. doi: 10.1016/j.jgg.2015.02.003. Epub 2015 Feb 17.
8.	Adverse Cardiovascular Outcomes and Antihypertensive Treatment: A Genome-Wide Interaction Meta-Analysis in the International Consortium for Antihypertensive Pharmacogenomics Studies.	McDonough CW, etal., Clin Pharmacol Ther. 2021 Sep;110(3):723-732. doi: 10.1002/cpt.2355. Epub 2021 Aug 15.
9.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
10.	The IgLON family in epithelial ovarian cancer: expression profiles and clinicopathologic correlates.	Ntougkos E, etal., Clin Cancer Res. 2005 Aug 15;11(16):5764-8. doi: 10.1158/1078-0432.CCR-04-2388.
11.	Steroid hormones and hormone antagonists regulate the neural marker neurotrimin in uterine leiomyoma.	Parikh TP, etal., Fertil Steril. 2020 Jan;113(1):176-186. doi: 10.1016/j.fertnstert.2019.08.090.
12.	GOA pipeline	RGD automated data pipeline
13.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
15.	Ectodomain shedding of Limbic System-Associated Membrane Protein (LSAMP) by ADAM Metallopeptidases promotes neurite outgrowth in DRG neurons.	Sanz RL, etal., Sci Rep. 2017 Aug 11;7(1):7961. doi: 10.1038/s41598-017-08315-0.
16.	Cloning of neurotrimin defines a new subfamily of differentially expressed neural cell adhesion molecules.	Struyk AF, etal., J Neurosci 1995 Mar;15(3 Pt 2):2141-56.
17.	Overexpression of IgLON cell adhesion molecules changes proliferation and cell size of cortical astrocytes.	Sugimoto C, etal., Cell Biochem Funct. 2012 Jul;30(5):400-5. doi: 10.1002/cbf.2813. Epub 2012 Feb 28.
18.	Genome-wide analysis of central corneal thickness in primary open-angle glaucoma cases in the NEIGHBOR and GLAUGEN consortia.	Ulmer M, etal., Invest Ophthalmol Vis Sci. 2012 Jul 3;53(8):4468-74. doi: 10.1167/iovs.12-9784.
19.	miR-182 inhibits Schwann cell proliferation and migration by targeting FGF9 and NTM, respectively at an early stage following sciatic nerve injury.	Yu B, etal., Nucleic Acids Res. 2012 Nov 1;40(20):10356-65. doi: 10.1093/nar/gks750. Epub 2012 Aug 23.

Additional References at PubMed

PMID:21700703	PMID:29476059

Genomics

Comparative Map Data

Ntm
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	35,634,929 - 36,625,081 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	8	35,635,640 - 36,624,807 (-)	Ensembl				GRCr8
mRatBN7.2	8	27,376,582 - 28,366,604 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	27,377,773 - 28,366,595 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	8	31,432,377 - 31,859,793 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	29,726,707 - 30,154,131 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	27,606,506 - 28,040,870 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	30,039,332 - 31,041,755 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	30,039,408 - 30,222,036 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	8	30,073,163 - 31,070,882 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	8	28,587,019 - 29,019,888 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	8	28,861,001 - 29,285,304 (-)	NCBI		Celera
RGSC_v3.1	8	28,587,115 - 29,019,985 (-)	NCBI
Cytogenetic Map	8	q13	NCBI

NTM
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	131,370,615 - 132,336,822 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	131,370,478 - 132,336,822 (+)	Ensembl			hg38	GRCh38
GRCh37	11	131,240,510 - 132,206,716 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	130,745,581 - 131,711,926 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	11	128,409,354 - 129,378,081 (+)	NCBI		Celera
Cytogenetic Map	11	q25	NCBI
HuRef	11	127,951,230 - 128,162,504 (+)	NCBI		HuRef
CHM1_1	11	131,126,401 - 132,093,912 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	131,406,501 - 132,375,341 (+)	NCBI		T2T-CHM13v2.0

Ntm
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	28,906,045 - 29,874,565 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	28,906,046 - 29,874,437 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	9	28,994,749 - 29,963,269 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	28,994,750 - 29,963,141 (-)	Ensembl			mm10	GRCm38
MGSCv37	9	28,803,549 - 29,770,714 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	9	28,745,410 - 29,712,575 (-)	NCBI		MGSCv36	mm8
Celera	9	26,253,249 - 27,220,687 (-)	NCBI		Celera
Cytogenetic Map	9	A4	NCBI
cM Map	9	14.38	NCBI

Ntm
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955412	32,227,794 - 33,195,101 (+)	Ensembl
ChiLan1.0	NW_004955412	32,779,245 - 33,194,093 (+)	NCBI	ChiLan1.0	ChiLan1.0

NTM
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	132,056,779 - 133,022,464 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	133,167,529 - 134,134,107 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	126,189,660 - 127,154,890 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	130,080,305 - 131,039,557 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	130,617,876 - 131,037,876 (+)	Ensembl			panPan2	panpan1.1

NTM
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	2,725,902 - 3,658,635 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	2,725,943 - 3,658,311 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	2,850,542 - 3,784,405 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	2,685,223 - 3,619,683 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	2,685,165 - 3,619,397 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	2,722,315 - 3,270,318 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	2,715,836 - 3,662,198 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	2,755,475 - 3,689,538 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Ntm
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	113,339,431 - 114,283,637 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936572	165,987 - 1,110,587 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936572	165,985 - 1,110,936 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NTM
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	58,743,504 - 58,968,355 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	9	57,965,751 - 58,967,534 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	65,007,525 - 65,420,592 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NTM
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	122,405,280 - 123,378,287 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	123,182,630 - 123,379,429 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666043	2,652,069 - 3,694,480 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ntm
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624812	5,834,748 - 6,812,837 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624812	5,834,367 - 6,812,623 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Ntm
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	8	24,829,138 - 25,780,641 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Ntm
7679 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	51
Count of miRNA genes:	47
Interacting mature miRNAs:	50
Transcripts:	ENSRNOT00000035454
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1357398	Slep3	Serum leptin concentration QTL 3	3.43		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	8	17994105	50763951	Rat
1358896	Bp262	Blood pressure QTL 262	2.89		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	35464071	107982864	Rat
2317030	Wbc5	White blood cell count QTL 5	3.21	0.005	leukocyte quantity (VT:0000217)	white blood cell count (CMO:0000027)	8	16994642	61994642	Rat
12880044	Am9	Aortic mass QTL 9		0.007	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	8	10382540	55382540	Rat
631648	Stl5	Serum triglyceride level QTL 5	4	0.0003	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	8	35464071	71842899	Rat
2317032	Ginf2	Gastrointestinal inflammation QTL 2	3.21	0.005	liver integrity trait (VT:0010547)	liver granuloma severity score (CMO:0002157)	8	12964165	57964165	Rat
2301416	Bp315	Blood pressure QTL 315		0.008	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	15952279	60952279	Rat
631842	Inf1	Infertility severity QTL 1	4.1	0.001	seminal gland mass (VT:0010524)	seminal vesicle wet weight (CMO:0001603)	8	31543661	76543661	Rat
2317036	Livw3	Liver weight QTL 3	2.43	0.01	liver mass (VT:0003402)	liver weight to body weight ratio (CMO:0000633)	8	12964165	57964165	Rat
1358907	Cm40	Cardiac mass QTL 40	1.89		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	8	35464071	107982864	Rat
1598824	Memor4	Memory QTL 4	2.5		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	8	17993862	62252873	Rat
12880023	Bw184	Body weight QTL 184		0.001	body mass (VT:0001259)	body weight (CMO:0000012)	8	10382540	55382540	Rat
12880028	Cm103	Cardiac mass QTL 103		0.02	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	8	10382540	55382540	Rat
2317051	Aia18	Adjuvant induced arthritis QTL 18	2.42		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	8	16994642	61994642	Rat
1358892	Kidm26	Kidney mass QTL 26	3.69		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	8	35464071	107982864	Rat
1359021	Bp271	Blood pressure QTL 271	1.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	34125902	55607752	Rat
2317048	Ginf1	Gastrointestinal inflammation QTL 1	3.52	0.005	cecum mucosa thickness (VT:0010234)	enterocolitis severity score (CMO:0002138)	8	12964165	57964165	Rat
2302367	Slep5	Serum leptin concentration QTL 5	3.43		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	8	17994105	50763951	Rat
12880025	Cm102	Cardiac mass QTL 102		0.044	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	8	10382540	55382540	Rat

Markers in Region

RH142564

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	27,723,411 - 27,723,602 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	30,398,813 - 30,399,003	NCBI	Rnor6.0
Rnor_5.0	8	30,431,408 - 30,431,598	UniSTS	Rnor5.0
RGSC_v3.4	8	28,936,809 - 28,936,999	UniSTS	RGSC3.4
Celera	8	29,204,580 - 29,204,770	UniSTS
RH 3.4 Map	8	241.7	UniSTS
Cytogenetic Map	8	q13	UniSTS

BE108548

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	27,800,843 - 27,800,998 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	30,476,029 - 30,476,183	NCBI	Rnor6.0
Rnor_5.0	8	30,508,056 - 30,508,210	UniSTS	Rnor5.0
RGSC_v3.4	8	29,016,499 - 29,016,653	UniSTS	RGSC3.4
Celera	8	29,281,919 - 29,282,073	UniSTS
RH 3.4 Map	8	240.4	UniSTS
Cytogenetic Map	8	q13	UniSTS

BE105927

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	27,381,119 - 27,381,269 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	30,043,869 - 30,044,018	NCBI	Rnor6.0
Rnor_5.0	8	30,077,700 - 30,077,849	UniSTS	Rnor5.0
RGSC_v3.4	8	28,590,366 - 28,590,515	UniSTS	RGSC3.4
Celera	8	28,864,348 - 28,864,497	UniSTS
RH 3.4 Map	8	241.5	UniSTS
Cytogenetic Map	8	q13	UniSTS

Genetic Models

This gene Ntm is modified in the following models/strains:

F344-Ntm^{Tn(sb-T2/Bart3)2.130Mcwi}

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
11	13	66	183	91	90	59	34	59	6	299	135	14	163	86	93	31	32	32

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001431454	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001431455	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001431456	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001431457	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001431458	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001431459	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001431460	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001431461	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_017354	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006242749	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008766065	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017595865	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017595866	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017595867	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039082005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039082006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039082007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC094830	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC110642	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ212682	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ231395	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U16845	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000035454 ⟹ ENSRNOP00000037037

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	8	30,039,408 - 30,222,036 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000094487 ⟹ ENSRNOP00000090247

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	35,635,640 - 36,624,807 (-)	Ensembl
mRatBN7.2 Ensembl	8	27,377,773 - 27,804,451 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000107198 ⟹ ENSRNOP00000085993

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	35,636,119 - 36,624,807 (-)	Ensembl
mRatBN7.2 Ensembl	8	27,377,773 - 28,366,595 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000135693 ⟹ ENSRNOP00000099382

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	35,635,640 - 36,624,807 (-)	Ensembl

RefSeq Acc Id:

NM_017354 ⟹ NP_059050

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	35,636,119 - 36,062,550 (-)	NCBI
mRatBN7.2	8	27,377,773 - 27,804,228 (-)	NCBI
Rnor_6.0	8	30,040,522 - 30,479,413 (-)	NCBI
Rnor_5.0	8	30,073,163 - 31,070,882 (-)	NCBI
RGSC_v3.4	8	28,587,019 - 29,019,888 (-)	RGD
Celera	8	28,861,001 - 29,285,304 (-)	RGD

Sequence:

show sequence

CAACTTAAGAAAGTGCTGGATTTCCCGTTGTTCGATTGAGGAACCGTAGACCACATCTGGGTAG
CTGGATTCAGCCCAGCCACAGCCCCGTTGGATACCAAAGTGCTTACTCCTGTCCAAAGTGCCAT
GCCTGAACTGCTACGGGGAAGAGGCAGCTTCTGAGACCCGCACCTGTGCGCCTGCTTGCCTGCC
TTGCGCTTCTCTCTCCTGGCCACCTTCCTGGCCACAGGCAGCACGGAGAAAGTCCGCCTCGGAT
GTGTGTGGAAACTGGTTCTCAGAGGCTGCGAGCTGAGGCTGGATTTAGGGGAGGAATATTAGAC
TTGGAGGAGTCTGCGCGCTTTTCTCCTCCCAGTGCATCGCGCGGTCGCCGCTAGTTCATCGCTG
GGTCCCCGCGCTCACTCCCCACCCCACCCACTTCCTGTGCTCGCCCGGGGGGCGTGTGCGTGCC
ACTACCGGAGTTCTGGGAAGTTGTGGCTGTCGAGAATGGGGGTCTGTGGGTACCTGTTCCTGCC
CTGGAAGTGCCTCGTGGTCGTGTCTCTCAGGCTGCTGTTCCTTGTACCCACAGGAGTGCCGGTG
CGTAGCGGAGATGCCACCTTTCCCAAAGCTATGGACAACGTGACGGTCAGGCAGGGGGAGAGCG
CCACCCTCAGGTGCACAATTGACAACCGAGTCACCCGGGTGGCCTGGCTAAACCGCAGTACCAT
CCTCTATGCTGGAAATGACAAGTGGTGCCTAGATCCTCGTGTGGTTCTCCTGAGTAACACCCAG
ACCCAGTACAGCATTGAGATCCAGAATGTGGATGTGTATGATGAGGGCCCTTATACCTGCTCGG
TGCAGACAGACAACCACCCTAAGACCTCCAGGGTCCACCTCATTGTACAAGTATCTCCCAAAAT
TGTAGAGATTTCTTCAGATATCTCCATTAATGAAGGGAACAACATCAGCCTCACTTGCATAGCC
ACAGGTAGACCGGAGCCTACAGTAACCTGGAGACATATTTCTCCCAAAGCTGTCGGCTTTGTGA
GTGAGGATGAGTACCTGGAGATCCAGGGCATCACTCGGGAGCAGTCAGGCGAGTATGAGTGCAG
CGCCTCCAACGACGTGGCAGCACCAGTCGTACGAAGAGTGAACGTCACCGTGAACTATCCACCA
TACATCTCAGAAGCTAAGGGTACAGGTGTCCCCGTGGGGCAGAAGGGGACTCTGCAGTGTGAAG
CCTCGGCAGTCCCTTCAGCAGAATTTCAGTGGTTCAAGGATGACAAAAGACTGGTTGAAGGGAA
GAAGGGAGTCAAAGTGGAAAACAGACCTTTCCTTTCAAGACTCACCTTTTTCAACGTCTCTGAA
CACGACTATGGGAACTACACATGTGTGGCATCCAACAAGTTGGGCCACACCAATGCCAGCATCA
TGCTATTTGGCCCAGGTGCTGTCAGCGAGGTCAACAATGGGACGTCAAGGAGGGCAGGCTGCAT
TTGGCTCCTCCCTCTTCTGGTCTTACACCTGCTCCTCAAATTTTGATGTGAGTGCCCCTTCCCT
GCCGGGGAGAGCTGCTGCCACCGCATCTCAATTCAACAGCACTGCAACATGAAGCAACAAGTCA
GAATCAAATGAAATTCCGAGAATCACAGCCAATGAGACAGAAATTCGAGGGAGGGGAACAAAGC
ATACTGTGGTAAAGGGGAAAAAAAAAGTCTAAAAAAAGGAAATTTGAAAATTGCCTTGCAGACA
TTTCGGTACCACTGAGTTTTCTTTCTTTTCCCAAATGGGAAGAAGGCGCACCTAGCTTGGACCC
ACCCACAAGCTGCACTGTGTGACCTCTCTGTTGCCAGGGTGGGCAAGGGCTCAGCCACTCTGCC
CACTAAAGTGCCCCACCATGGAACATTCTGGAGTCGGCCATCCCAAATTTCATCGGTCCATAGA
CACAAGCACAGAGTGAGAAACAGGGGCCCAGAAGTGCCACGGAGGGCCCTTTGGTGGGCTGCGC
GATGGTGGCGTGTGTCATGAAGTGTGAAATCCGAAGTAGAAAAAAAACAAGAATAA

hide sequence

RefSeq Acc Id:

XM_017595865 ⟹ XP_017451354

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	35,634,929 - 36,624,963 (-)	NCBI
mRatBN7.2	8	27,376,582 - 28,366,604 (-)	NCBI
Rnor_6.0	8	30,039,332 - 31,041,755 (-)	NCBI

Sequence:

show sequence

GTCAATCCTTGGATTAGAACCAATGATTGCAGCTTGTAGGAGGGCTGTCCAGGGCCAGATTGTA
CAATGTGCCTCAGTGCCAGAGTATGAGTGGAGATAATTACGGAGAAGTCAGACTCTCTCTCGCC
CTCGGCTTCCTTGTTGTGTCCTTCAGCAAAACAGTGGATTTAAATCTCCTCGGACTAGCTTGAG
AGCAACACAATCTATCAGGAGGAAAAAGGAAAGAAAGAGGGAGAAAAAAAACCGATCCTGACAA
AAAAGAAGAAAAAGAAGAAAAATATGAAAACCATCCAGGCAAAAATGCACAATTCTATCTCGTG
GGCAATCTTCACGGGGCTGGCTGCTCTGTGCCTCTTCCAAGGAGTGCCGGTGCGTAGCGGAGAT
GCCACCTTTCCCAAAGCTATGGACAACGTGACGGTCAGGCAGGGGGAGAGCGCCACCCTCAGGT
GCACAATTGACAACCGAGTCACCCGGGTGGCCTGGCTAAACCGCAGTACCATCCTCTATGCTGG
AAATGACAAGTGGTGCCTAGATCCTCGTGTGGTTCTCCTGAGTAACACCCAGACCCAGTACAGC
ATTGAGATCCAGAATGTGGATGTGTATGATGAGGGCCCTTATACCTGCTCGGTGCAGACAGACA
ACCACCCTAAGACCTCCAGGGTCCACCTCATTGTACAAGTATCTCCCAAAATTGTAGAGATTTC
TTCAGATATCTCCATTAATGAAGGGAACAACATCAGCCTCACTTGCATAGCCACAGGTAGACCG
GAGCCTACAGTAACCTGGAGACATATTTCTCCCAAAGCTGTCGGCTTTGTGAGTGAGGATGAGT
ACCTGGAGATCCAGGGCATCACTCGGGAGCAGTCAGGCGAGTATGAGTGCAGCGCCTCCAACGA
CGTGGCAGCACCAGTCGTACGAAGAGTGAAGGTCACCGTGAACTATCCACCATACATCTCAGAA
GCTAAGGGTACAGGTGTCCCCGTGGGGCAGAAGGGGACTCTGCAGTGTGAAGCCTCGGCAGTCC
CTTCAGCAGAATTTCAGTGGTTCAAGGATGACAAAAGACTGGTTGAAGGGAAGAAGGGAGTCAA
AGTGGAAAACAGACCTTTCCTTTCAAGACTCACCTTTTTCAACGTCTCTGAACACGACTATGGG
AACTACACATGTGTGGCATCCAACAAGTTGGGCCACACCAATGCCAGCATCATGCTATTTGAAC
TAAATGAGCCTACAAGCTCAACTTTATTGCAAGAAGTGAAAACTACAGCCCTGACCCCTTGGAA
AGGCCCAGGTGCTGTCAGCGAGGTCAACAATGGGACGTCAAGGAGGGCAGGCTGCATTTGGCTC
CTCCCTCTTCTGGTCTTACACCTGCTCCTCAAATTTTGATGTGAGTGCCCCTTCCCTGCCGGGG
AGAGCTGCTGCCACCGCATCTCAATTCAACAGCACTGCAACATGAAGCAACAAGTCAGAATCAA
ATGAAATTCCGAGAATCACAGCCAATGAGACAGAAATTCGAGGGAGGGGAACAAAGCATACTGT
GGTAAAGGGGAAAAAAAAGTCTAAAAAAAGGAAATTTGAAAATTGCCTTGCAGACATTTCGGTA
CCACTGAGTTTTCTTTCTTTTCCCAAATGGGAAGAAGGCGCACCTAGCTTGGACCCACCCACAA
GCTGCACTGTGTGACCTCTCTGTTGCCAGGGTGGGCAAGGGCTCAGCCACTCTGCCCACTAAAG
TGCCCCACCATGGAACATTCTGGAGTCGGCCATCCCAAATTTCATCGGTCCATAGACACAAGCA
CAGAGTGAGAAACAGGGGCCCAGAAGTGCCACGGAGGGCCCTTTGGTGGGCTGCGCGATGATGG
CGTGTGTCATGAAGTGTGAAATCCGAAGTAGAAAAAAAAACAAGAATAAAAAAAGAAGAGAAGA
AAGAAGAAAGAACAAACGAAACAAGACAGCCTGACAGCACCATAACCCCACAAGCAACAGTCAC
AAAAGACACCGTTAAGCTTTCGGTTTTTTTTTTTTTTTTTTCATTTTACCACATGGACATCATG
GATAATAAGGGATTCTGATTCATTGTTAATTTTATTAATTATATTTTCTGATATGAGTCTAGAA
CTTAGGGCAAAAACAAGAGACAAAACTAAAATTACACAGGCAAGGGTGAAGGGAAGCGTGTTTC
TTAAGTATTAAAAGTGAATAGTATACTTCTTACCTAAGTTTACAACTGGTGGACCAGACACCAG
GCACTAACCACCTGGCGAGGCTTTGGCAAATCCACCAGACACACATGTGATTTAACAAACACCT
CCACCAGCGTCATAGATTCCTCCTCATCTCTTGCAGACAGAACTATGCTATCTATACACTACTT
AGACACGGAAGGTTGGTCTGCACTCTATCTTGGTTTGTTGGCTATGCTTCTTTTGATGACATAT
ATTATACAGTATATATATATATATACATATATTTTTTTTTGTTAGAGTTCTAGCCATTTTCTTT
CTCAGCAGGGTCCTTCTCAGACATTACTGCATGCTGTATATGGCGTTAGCTGTGTGTTGATCTT
CTAAAAGATGATAGAGTTTACCGGTAATTGTGTAATCAGCTCCTTCCTTTTTTTTTTTCCCTTG
GGTTATTTACATGTCAGAGACATTTCTACAAAGCAGAAAGGACAACAGAAACAATAACTAATAC
CAGGCGCAGCATCTTTCCGGGTGTGGCTCTCTGAGGAGGAGGCTACCAGCTTGGCTTCTCCATC
ACACCTTGGGGCATTAACGGACAGCAAGCAACTGAAACAACTAAACCAACAGTAATCACTTGCT
TTAGCCCATTGTGGGAATCCCTGATGCCTTTTGTGACTACTGGAGAACTTAATCCTCTTGGTTT
ATTTTATTTAATTTTCCACCCTTGTGTGAGTGCGTATGAAAGAGAAGAAAAATGCAGTTTTTAG
GTAACCATTTTTTCCTTCCCCGAAGTCTGGGGACCAGAGAGGCCTCGGGGAGGGGTCCTGGATG
TGATGAGGGAAACTGGGATTGGGGGAATAGGGGAGGGATGGGTTGTCTCTGACTTGACATTAAA
AAAGTGTTCCATGTCCCTCTTCA

hide sequence

RefSeq Acc Id:

XM_039082005 ⟹ XP_038937933

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	35,634,929 - 36,625,081 (-)	NCBI
mRatBN7.2	8	27,376,582 - 28,366,604 (-)	NCBI

RefSeq Acc Id:

XM_039082006 ⟹ XP_038937934

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	35,634,929 - 36,624,947 (-)	NCBI
mRatBN7.2	8	27,376,582 - 28,366,603 (-)	NCBI

RefSeq Acc Id:

XM_039082007 ⟹ XP_038937935

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	35,634,929 - 36,624,978 (-)	NCBI
mRatBN7.2	8	27,376,582 - 28,366,596 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001418383	(Get FASTA)	NCBI Sequence Viewer
	NP_001418384	(Get FASTA)	NCBI Sequence Viewer
	NP_001418385	(Get FASTA)	NCBI Sequence Viewer
	NP_001418386	(Get FASTA)	NCBI Sequence Viewer
	NP_001418387	(Get FASTA)	NCBI Sequence Viewer
	NP_001418388	(Get FASTA)	NCBI Sequence Viewer
	NP_001418389	(Get FASTA)	NCBI Sequence Viewer
	NP_001418390	(Get FASTA)	NCBI Sequence Viewer
	NP_059050	(Get FASTA)	NCBI Sequence Viewer
	XP_017451354	(Get FASTA)	NCBI Sequence Viewer
	XP_038937933	(Get FASTA)	NCBI Sequence Viewer
	XP_038937934	(Get FASTA)	NCBI Sequence Viewer
	XP_038937935	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA67445	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000085993
	ENSRNOP00000090247
	ENSRNOP00000099382
GenBank Protein	Q62718	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_059050 ⟸ NM_017354
- Peptide Label:	precursor
- UniProtKB:	Q62718 (UniProtKB/Swiss-Prot), A0A8I6AE09 (UniProtKB/TrEMBL), A6JYE7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGVCGYLFLPWKCLVVVSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDNRVT RVAWLNRSTILYAGNDKWCLDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRV HLIVQVSPKIVEISSDISINEGNNISLTCIATGRPEPTVTWRHISPKAVGFVSEDEYLEIQGIT REQSGEYECSASNDVAAPVVRRVNVTVNYPPYISEAKGTGVPVGQKGTLQCEASAVPSAEFQWF KDDKRLVEGKKGVKVENRPFLSRLTFFNVSEHDYGNYTCVASNKLGHTNASIMLFGPGAVSEVN NGTSRRAGCIWLLPLLVLHLLLKF hide sequence

RefSeq Acc Id:

XP_017451354 ⟸ XM_017595865

- Peptide Label:

isoform X1

- Sequence:

show sequence

MKTIQAKMHNSISWAIFTGLAALCLFQGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDNRVT
RVAWLNRSTILYAGNDKWCLDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRV
HLIVQVSPKIVEISSDISINEGNNISLTCIATGRPEPTVTWRHISPKAVGFVSEDEYLEIQGIT
REQSGEYECSASNDVAAPVVRRVKVTVNYPPYISEAKGTGVPVGQKGTLQCEASAVPSAEFQWF
KDDKRLVEGKKGVKVENRPFLSRLTFFNVSEHDYGNYTCVASNKLGHTNASIMLFELNEPTSST
LLQEVKTTALTPWKGPGAVSEVNNGTSRRAGCIWLLPLLVLHLLLKF

hide sequence

Ensembl Acc Id:

ENSRNOP00000037037 ⟸ ENSRNOT00000035454

RefSeq Acc Id:	XP_038937933 ⟸ XM_039082005
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038937934 ⟸ XM_039082006
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038937935 ⟸ XM_039082007
- Peptide Label:	isoform X4

Ensembl Acc Id:

ENSRNOP00000090247 ⟸ ENSRNOT00000094487

Ensembl Acc Id:

ENSRNOP00000085993 ⟸ ENSRNOT00000107198

Ensembl Acc Id:

ENSRNOP00000099382 ⟸ ENSRNOT00000135693

Protein Domains

Ig-like Ig-like C2-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q62718-F1-model_v2	AlphaFold	Q62718	1-344	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620958	AgrOrtholog
BioCyc Gene	G2FUF-31294	BioCyc
Ensembl Genes	ENSRNOG00000023720	Ensembl
	ENSRNOG00000066437	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000094487	ENTREZGENE
	ENSRNOT00000107198	ENTREZGENE
	ENSRNOT00000135693	ENTREZGENE
Gene3D-CATH	2.60.40.10	UniProtKB/Swiss-Prot
InterPro	Ig-like_dom	UniProtKB/Swiss-Prot
	Ig-like_dom_sf	UniProtKB/Swiss-Prot
	Ig-like_fold	UniProtKB/Swiss-Prot
	Ig_I-set	UniProtKB/Swiss-Prot
	Ig_sub	UniProtKB/Swiss-Prot
	Ig_sub2	UniProtKB/Swiss-Prot
	IgLON_domain	UniProtKB/Swiss-Prot
	Immunoglobulin	UniProtKB/Swiss-Prot
KEGG Report	rno:50864	UniProtKB/Swiss-Prot
NCBI Gene	50864	ENTREZGENE
PANTHER	IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED	UniProtKB/Swiss-Prot
	NEUROTRIMIN	UniProtKB/Swiss-Prot
Pfam	I-set	UniProtKB/Swiss-Prot
	Ig_3	UniProtKB/Swiss-Prot
	PF00047	UniProtKB/Swiss-Prot
PhenoGen	Ntm	PhenoGen
PROSITE	IG_LIKE	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000023720	RatGTEx
	ENSRNOG00000066437	RatGTEx
SMART	IGc2	UniProtKB/Swiss-Prot
	SM00409	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF48726	UniProtKB/Swiss-Prot
UniProt	A0A8I6AE09	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6GEH9	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0KXF1_RAT	UniProtKB/TrEMBL
	A6JYE7	ENTREZGENE, UniProtKB/TrEMBL
	NTRI_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-01-20	Hnt	neurotrimin	RNU16845		Symbol updated	1299863	APPROVED
2002-08-07	RNU16845	neurotrimin			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_domains	contains three immunoglobulin like domains	633890

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar