Zbtb7a (zinc finger and BTB domain containing 7A) - Rat Genome Database

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Gene: Zbtb7a (zinc finger and BTB domain containing 7A) Rattus norvegicus
Analyze
Symbol: Zbtb7a
Name: zinc finger and BTB domain containing 7A
RGD ID: 620946
Description: Enables DNA-binding transcription factor activity. Involved in regulation of DNA-templated transcription and regulation of osteoclast differentiation. Predicted to be located in cytoplasm. Predicted to be part of DNA-dependent protein kinase complex. Predicted to be active in nucleus. Predicted to colocalize with site of double-strand break. Orthologous to human ZBTB7A (zinc finger and BTB domain containing 7A); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: leukemia/lymphoma related factor; leukemia/lymphoma-related factor; Lrf; OCZF; osteoclast-derived zinc finger; Zbtb7; zinc finger and BTB domain-containing protein 7A
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr879,211,733 - 9,229,273 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl79,214,496 - 9,227,252 (-)EnsemblGRCr8
mRatBN7.278,561,015 - 8,578,243 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl78,563,779 - 8,576,539 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx711,448,841 - 11,461,603 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0713,324,328 - 13,337,091 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0711,190,783 - 11,203,558 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0711,429,266 - 11,446,119 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl711,432,049 - 11,444,786 (-)Ensemblrn6Rnor6.0
Rnor_5.0711,596,630 - 11,613,467 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4710,047,586 - 10,060,456 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera76,751,640 - 6,757,036 (-)NCBICelera
RGSC_v3.1710,047,608 - 10,052,982 (-)NCBI
Cytogenetic Map7q11NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Osteoclast-derived zinc finger (OCZF) protein with POZ domain, a possible transcriptional repressor, is involved in osteoclastogenesis. Kukita A, etal., Blood 1999 Sep 15;94(6):1987-97.
3. Leukemia/lymphoma-related factor, a POZ domain-containing transcriptional repressor, interacts with histone deacetylase-1 and inhibits cartilage oligomeric matrix protein gene expression and chondrogenesis. Liu CJ, etal., J Biol Chem. 2004 Nov 5;279(45):47081-91. Epub 2004 Aug 26.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12004059   PMID:14701838   PMID:15662416   PMID:15917220   PMID:17495164   PMID:17595526   PMID:20812024   PMID:24514149   PMID:24772825   PMID:25514493   PMID:26446488   PMID:26455326  
PMID:26816381   PMID:29813070   PMID:35474350  


Genomics

Comparative Map Data
Zbtb7a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr879,211,733 - 9,229,273 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl79,214,496 - 9,227,252 (-)EnsemblGRCr8
mRatBN7.278,561,015 - 8,578,243 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl78,563,779 - 8,576,539 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx711,448,841 - 11,461,603 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0713,324,328 - 13,337,091 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0711,190,783 - 11,203,558 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0711,429,266 - 11,446,119 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl711,432,049 - 11,444,786 (-)Ensemblrn6Rnor6.0
Rnor_5.0711,596,630 - 11,613,467 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4710,047,586 - 10,060,456 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera76,751,640 - 6,757,036 (-)NCBICelera
RGSC_v3.1710,047,608 - 10,052,982 (-)NCBI
Cytogenetic Map7q11NCBI
ZBTB7A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38194,043,303 - 4,066,899 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl194,043,303 - 4,067,636 (-)Ensemblhg38GRCh38
GRCh37194,043,301 - 4,066,897 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36193,996,216 - 4,017,816 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34193,996,216 - 4,017,816NCBI
Celera193,984,710 - 4,006,260 (-)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef193,809,524 - 3,824,110 (-)NCBIHuRef
CHM1_1194,044,801 - 4,066,422 (-)NCBICHM1_1
T2T-CHM13v2.0194,026,415 - 4,050,025 (-)NCBIT2T-CHM13v2.0
Zbtb7a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391080,971,113 - 80,988,056 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1080,971,054 - 80,988,829 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381081,135,225 - 81,152,222 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1081,135,220 - 81,152,995 (+)Ensemblmm10GRCm38
MGSCv371080,599,016 - 80,614,402 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361080,539,400 - 80,554,393 (+)NCBIMGSCv36mm8
Celera1082,156,627 - 82,172,013 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
Zbtb7a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554954,740,901 - 4,753,992 (+)Ensembl
ChiLan1.0NW_0049554954,747,905 - 4,754,066 (+)NCBIChiLan1.0ChiLan1.0
ZBTB7A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2208,440,492 - 8,466,499 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1197,670,621 - 7,694,593 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0193,066,554 - 3,090,285 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1194,013,208 - 4,037,630 (-)NCBIPanPan1.1PanPan1.1panPan2
ZBTB7A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12055,517,531 - 55,527,071 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2055,505,916 - 55,523,736 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2055,233,807 - 55,252,980 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02056,169,484 - 56,187,224 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2056,166,283 - 56,182,676 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12055,224,406 - 55,243,571 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02055,705,817 - 55,724,966 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02055,904,666 - 55,923,869 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Zbtb7a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118215,512,758 - 215,525,208 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365882,311,727 - 2,321,372 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365882,310,975 - 2,321,790 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZBTB7A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl274,681,193 - 74,694,869 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1274,678,293 - 74,699,347 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2275,223,154 - 75,243,600 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ZBTB7A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.163,802,171 - 3,824,552 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl63,801,046 - 3,812,884 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660814,418,198 - 4,441,462 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Zbtb7a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248285,530,543 - 5,545,902 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248285,529,351 - 5,548,481 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Zbtb7a
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11153,734,489 - 153,743,359 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Zbtb7a
150 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:117
Count of miRNA genes:81
Interacting mature miRNAs:94
Transcripts:ENSRNOT00000027323
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7166965846669658Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)7123748937Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7721609752216097Rat
2290372Gluco33Glucose level QTL 332.71blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)7131777942Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)71104117804Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7170952746709527Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7132612984Rat
1582260Bw72Body weight QTL 723.20.0043body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582261Bw69Body weight QTL 693.20.0048body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582262Bw75Body weight QTL 7530.0038body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7129716167Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134650782Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7132612984Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001439481 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001439482 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001439483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001439484 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_054002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006240836 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006240837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006240838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594615 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262898 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC120292 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D88450 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212204 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221382 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000027323   ⟹   ENSRNOP00000027323
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl79,214,516 - 9,227,252 (-)Ensembl
mRatBN7.2 Ensembl78,563,799 - 8,576,539 (-)Ensembl
Rnor_6.0 Ensembl711,432,049 - 11,444,786 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000082126   ⟹   ENSRNOP00000073998
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl79,214,496 - 9,226,207 (-)Ensembl
mRatBN7.2 Ensembl78,563,779 - 8,575,536 (-)Ensembl
Rnor_6.0 Ensembl711,432,049 - 11,443,357 (-)Ensembl
RefSeq Acc Id: NM_054002   ⟹   NP_446454
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr879,214,493 - 9,227,252 (-)NCBI
mRatBN7.278,563,776 - 8,576,539 (-)NCBI
Rnor_6.0711,432,026 - 11,444,786 (-)NCBI
Rnor_5.0711,596,630 - 11,613,467 (-)NCBI
RGSC_v3.4710,047,586 - 10,060,456 (-)RGD
Celera76,751,640 - 6,757,036 (-)RGD
Sequence:
RefSeq Acc Id: XM_006240836   ⟹   XP_006240898
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr879,211,733 - 9,226,570 (-)NCBI
mRatBN7.278,561,015 - 8,575,859 (-)NCBI
Rnor_6.0711,429,266 - 11,444,082 (-)NCBI
Rnor_5.0711,596,630 - 11,613,467 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006240837   ⟹   XP_006240899
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr879,211,733 - 9,228,134 (-)NCBI
mRatBN7.278,561,015 - 8,576,978 (-)NCBI
Rnor_6.0711,429,266 - 11,445,233 (-)NCBI
Rnor_5.0711,596,630 - 11,613,467 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006240838   ⟹   XP_006240900
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr879,211,733 - 9,229,273 (-)NCBI
mRatBN7.278,561,015 - 8,578,243 (-)NCBI
Rnor_6.0711,429,266 - 11,446,119 (-)NCBI
Rnor_5.0711,596,630 - 11,613,467 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063262898   ⟹   XP_063118968
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr879,211,733 - 9,226,898 (-)NCBI
RefSeq Acc Id: NP_446454   ⟸   NM_054002
- UniProtKB: Q9QZ48 (UniProtKB/Swiss-Prot),   G3V8P6 (UniProtKB/TrEMBL),   A6K8C0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240900   ⟸   XM_006240838
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006240899   ⟸   XM_006240837
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006240898   ⟸   XM_006240836
- Peptide Label: isoform X1
- UniProtKB: Q9QZ48 (UniProtKB/Swiss-Prot),   A0A0G2K6Z3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000073998   ⟸   ENSRNOT00000082126
Ensembl Acc Id: ENSRNOP00000027323   ⟸   ENSRNOT00000027323
RefSeq Acc Id: XP_063118968   ⟸   XM_063262898
- Peptide Label: isoform X2
Protein Domains
BTB   C2H2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9QZ48-F1-model_v2 AlphaFold Q9QZ48 1-569 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694997
Promoter ID:EPDNEW_R5512
Type:single initiation site
Name:Zbtb7a_2
Description:zinc finger and BTB domain containing 7a
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R5513  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0711,443,373 - 11,443,433EPDNEW
RGD ID:13694988
Promoter ID:EPDNEW_R5513
Type:initiation region
Name:Zbtb7a_1
Description:zinc finger and BTB domain containing 7a
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R5512  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0711,444,798 - 11,444,858EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620946 AgrOrtholog
BioCyc Gene G2FUF-34997 BioCyc
Ensembl Genes ENSRNOG00000020161 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000027323 ENTREZGENE
  ENSRNOT00000082126 ENTREZGENE
Gene3D-CATH Classic Zinc Finger UniProtKB/Swiss-Prot
  Potassium Channel Kv1.1, Chain A UniProtKB/Swiss-Prot
InterPro BTB/POZ_dom UniProtKB/Swiss-Prot
  SKP1/BTB/POZ_sf UniProtKB/Swiss-Prot
  Znf_C2H2_sf UniProtKB/Swiss-Prot
  Znf_C2H2_type UniProtKB/Swiss-Prot
  ZnFinger_BTB_dom_contain UniProtKB/Swiss-Prot
KEGG Report rno:117107 UniProtKB/Swiss-Prot
NCBI Gene 117107 ENTREZGENE
PANTHER AGAP004733-PA UniProtKB/Swiss-Prot
  ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 7A UniProtKB/Swiss-Prot
Pfam BTB UniProtKB/Swiss-Prot
  zf-C2H2 UniProtKB/Swiss-Prot
PhenoGen Zbtb7a PhenoGen
PROSITE BTB UniProtKB/Swiss-Prot
  ZINC_FINGER_C2H2_1 UniProtKB/Swiss-Prot
  ZINC_FINGER_C2H2_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000020161 RatGTEx
SMART BTB UniProtKB/Swiss-Prot
  ZnF_C2H2 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF54695 UniProtKB/Swiss-Prot
  SSF57667 UniProtKB/Swiss-Prot
UniProt A0A0G2K6Z3 ENTREZGENE, UniProtKB/TrEMBL
  A6K8C0 ENTREZGENE, UniProtKB/TrEMBL
  G3V8P6 ENTREZGENE, UniProtKB/TrEMBL
  Q9QZ48 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2025-08-25 Zbtb7a  zinc finger and BTB domain containing 7A  Zbtb7a  zinc finger and BTB domain containing 7a  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-11-17 Zbtb7a  zinc finger and BTB domain containing 7a      Symbol and Name updated 1299863 APPROVED
2004-09-10 Zbtb7  leukemia/lymphoma related factor  Lrf    Symbol and Name updated 1299863 APPROVED
2002-08-07 Lrf  leukemia/lymphoma related factor      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_domains contains an N-terminal POZ domain and C-terminal Kruppel-like zinc fingers 633299
gene_expression expressed in osteoclasts and kidney cells 633299