Fbp2 (fructose-bisphosphatase 2) - Rat Genome Database

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Gene: Fbp2 (fructose-bisphosphatase 2) Rattus norvegicus
Analyze
Symbol: Fbp2
Name: fructose-bisphosphatase 2
RGD ID: 620930
Description: Enables fructose 1,6-bisphosphate 1-phosphatase activity. Involved in gluconeogenesis. Predicted to be located in Z disc; anchoring junction; and nucleus. Predicted to be active in cytosol. Orthologous to human FBP2 (fructose-bisphosphatase 2); PARTICIPATES IN gluconeogenesis pathway; fructose and mannose metabolic pathway; glycolysis pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 28-Homobrassinolide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: D-fructose-1,6-bisphosphate 1-phosphohydrolase 2; FBPase; FBPase 2; fructose bisphosphatase 2; fructose-1,6-bisphosphatase 2; fructose-1,6-bisphosphatase isozyme 2; muscle FBPase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8172,241,767 - 2,259,371 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl172,241,975 - 2,259,366 (+)EnsemblGRCr8
mRatBN7.2172,236,088 - 2,253,702 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl172,236,336 - 2,253,698 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx172,254,973 - 2,273,317 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0173,797,572 - 3,814,936 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0172,252,427 - 2,269,786 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.017372,554 - 389,918 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl17372,551 - 389,967 (-)Ensemblrn6Rnor6.0
Rnor_5.017367,702 - 385,066 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4177,824,298 - 7,841,661 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera17271,263 - 288,628 (-)NCBICelera
RGSC_v3.1177,824,297 - 7,841,657 (+)NCBI
Cytogenetic Map17p14NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dichloroethane  (ISO)
15-acetyldeoxynivalenol  (ISO)
17beta-estradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-amino-2-deoxy-D-glucopyranose  (ISO)
28-Homobrassinolide  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3-chloropropane-1,2-diol  (EXP)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
aldehydo-D-glucosamine  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
beta-D-glucosamine  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
carbon nanotube  (ISO)
cefaloridine  (EXP)
CGP 52608  (ISO)
choline  (ISO)
clofibrate  (EXP,ISO)
cyclosporin A  (ISO)
D-glucose  (ISO)
dexamethasone  (EXP)
Di-n-octyl phthalate  (ISO)
dibutyl phthalate  (EXP)
dioxygen  (ISO)
diquat  (ISO)
duvoglustat  (ISO)
epoxiconazole  (ISO)
fenofibrate  (EXP)
folic acid  (ISO)
fucoxanthin  (ISO)
furan  (EXP)
gentamycin  (EXP)
glucose  (ISO)
GW 4064  (ISO)
isotretinoin  (ISO)
L-methionine  (ISO)
manganese(II) chloride  (EXP)
methapyrilene  (ISO)
Muraglitazar  (EXP)
N-methyl-N-nitrosourea  (ISO)
ochratoxin A  (EXP)
ozone  (ISO)
paracetamol  (EXP)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
pirinixic acid  (EXP,ISO)
pravastatin  (EXP)
sodium arsenite  (ISO)
streptozocin  (ISO)
Tesaglitazar  (EXP)
testosterone  (EXP)
tetrachloroethene  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
trichloroethene  (EXP,ISO)
trichostatin A  (ISO)
Triptolide  (EXP)
troglitazone  (EXP)
valproic acid  (EXP,ISO)
zaragozic acid A  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
anchoring junction  (IEA)
cytoplasm  (IBA,IEA)
cytosol  (IBA,ISO)
nucleus  (IEA)
Z disc  (IEA)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Mechanism of fat-induced hepatic gluconeogenesis: effect of metformin. Song S, etal., Am J Physiol Endocrinol Metab. 2001 Aug;281(2):E275-82.
8. Regulation of fructose-1,6-bisphosphatase activity in primary cultured astrocytes. Verge V and Hevor TK, Neurochem Res 1995 Sep;20(9):1049-56.
9. Induction and suppression of the key enzymes of glycolysis and gluconeogenesis in isolated perfused rat liver in response to glucose, fructose and lactate. Wimhurst JM and Manchester KL, Biochem J. 1973 May;134(1):143-56.
Additional References at PubMed
PMID:15498578   PMID:19056867   PMID:22021109   PMID:25416956   PMID:29507044   PMID:31515488  


Genomics

Comparative Map Data
Fbp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8172,241,767 - 2,259,371 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl172,241,975 - 2,259,366 (+)EnsemblGRCr8
mRatBN7.2172,236,088 - 2,253,702 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl172,236,336 - 2,253,698 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx172,254,973 - 2,273,317 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0173,797,572 - 3,814,936 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0172,252,427 - 2,269,786 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.017372,554 - 389,918 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl17372,551 - 389,967 (-)Ensemblrn6Rnor6.0
Rnor_5.017367,702 - 385,066 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4177,824,298 - 7,841,661 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera17271,263 - 288,628 (-)NCBICelera
RGSC_v3.1177,824,297 - 7,841,657 (+)NCBI
Cytogenetic Map17p14NCBI
FBP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38994,558,720 - 94,593,824 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl994,558,720 - 94,593,824 (-)Ensemblhg38GRCh38
GRCh37997,321,002 - 97,356,106 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36996,360,823 - 96,395,896 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34994,400,559 - 94,435,630NCBI
Celera967,762,024 - 67,797,107 (-)NCBICelera
Cytogenetic Map9q22.32NCBI
HuRef966,929,657 - 66,964,734 (-)NCBIHuRef
CHM1_1997,467,108 - 97,502,191 (-)NCBICHM1_1
T2T-CHM13v2.09106,728,044 - 106,763,156 (-)NCBIT2T-CHM13v2.0
Fbp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391362,984,698 - 63,006,214 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1362,984,691 - 63,006,236 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381362,836,884 - 62,858,400 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1362,836,877 - 62,858,422 (-)Ensemblmm10GRCm38
MGSCv371362,938,245 - 62,959,730 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361362,846,505 - 62,867,939 (-)NCBIMGSCv36mm8
Celera1364,496,099 - 64,518,734 (-)NCBICelera
Cytogenetic Map13B3NCBI
cM Map1332.74NCBI
Fbp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542221,505,857 - 21,530,302 (-)Ensembl
ChiLan1.0NW_00495542221,508,906 - 21,530,296 (-)NCBIChiLan1.0ChiLan1.0
FBP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21144,863,836 - 44,900,354 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1944,866,218 - 44,902,736 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0965,650,460 - 65,685,794 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1993,780,956 - 93,815,872 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl993,780,956 - 93,815,872 (-)EnsemblpanPan2panpan1.1
FBP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1172,136,072 - 72,168,487 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl172,136,106 - 72,184,795 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha172,898,185 - 72,930,586 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0172,440,760 - 72,473,186 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl172,440,788 - 72,490,930 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1172,251,624 - 72,283,999 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0172,017,205 - 72,049,603 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0172,722,749 - 72,755,421 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Fbp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049444,293,631 - 4,319,818 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366263,521,953 - 3,548,195 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366263,521,953 - 3,548,206 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FBP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1027,631,496 - 27,665,246 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11027,631,833 - 27,661,704 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21031,837,933 - 31,900,482 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FBP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.112108,486,830 - 108,527,443 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl12108,493,645 - 108,527,219 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603896,889,075 - 96,926,197 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fbp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475315,980,116 - 16,010,489 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475315,981,008 - 16,010,389 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Fbp2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11476,642,964 - 76,660,403 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Fbp2
111 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:87
Count of miRNA genes:75
Interacting mature miRNAs:81
Transcripts:ENSRNOT00000023865
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10401807Kidm52Kidney mass QTL 52kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17131706603Rat
1354613Kidm14Kidney mass QTL 146.2kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)17136045694Rat
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17143999106Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17143999106Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17143999106Rat
1641902Colcr7Colorectal carcinoma resistance QTL 73.350.0044intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)17212084322087569Rat
2324619Coatc4Coat color QTL 40.001coat/hair pigmentation trait (VT:0010463)pigmented dorsal coat/hair area to total dorsal coat/hair area ratio (CMO:0001811)17121499218Rat
1300123Bp194Blood pressure QTL 1942.82arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)17212084342054133Rat
1549900Iddm20Insulin dependent diabetes mellitus QTL 203.7pancreas integrity trait (VT:0010560)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)17122181410Rat
9590316Scort21Serum corticosterone level QTL 214.750.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17122877318Rat
631207Niddm41Non-insulin dependent diabetes mellitus QTL 41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)17138037084Rat

Markers in Region
RH128752  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8172,259,140 - 2,259,325 (+)Marker Load Pipeline
mRatBN7.2172,253,471 - 2,253,656 (-)MAPPERmRatBN7.2
Rnor_6.017372,600 - 372,784NCBIRnor6.0
Rnor_5.017367,748 - 367,932UniSTSRnor5.0
RGSC_v3.4177,841,431 - 7,841,615UniSTSRGSC3.4
Celera17271,309 - 271,493UniSTS
RH 3.4 Map175.6UniSTS
Cytogenetic Map17p14UniSTS
Fbp2  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2172,253,497 - 2,253,659 (-)MAPPERmRatBN7.2
Rnor_6.017372,597 - 372,758NCBIRnor6.0
Rnor_5.017367,745 - 367,906UniSTSRnor5.0
RGSC_v3.4177,841,457 - 7,841,618UniSTSRGSC3.4
Celera17271,306 - 271,467UniSTS
Cytogenetic Map17p14UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 63 128 75 74 43 75 43 6 312 171 11 100 74 91 31 8 8

Sequence


Ensembl Acc Id: ENSRNOT00000023865   ⟹   ENSRNOP00000023865
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl172,241,975 - 2,259,366 (+)Ensembl
mRatBN7.2 Ensembl172,236,336 - 2,253,698 (+)Ensembl
Rnor_6.0 Ensembl17372,551 - 389,967 (-)Ensembl
RefSeq Acc Id: NM_053716   ⟹   NP_446168
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8172,242,008 - 2,259,371 (+)NCBI
mRatBN7.2172,236,336 - 2,253,702 (+)NCBI
Rnor_6.017372,554 - 389,918 (-)NCBI
Rnor_5.017367,702 - 385,066 (-)NCBI
RGSC_v3.4177,824,298 - 7,841,661 (+)RGD
Celera17271,263 - 288,628 (-)RGD
Sequence:
RefSeq Acc Id: XR_005495224
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8172,241,767 - 2,259,119 (+)NCBI
mRatBN7.2172,236,088 - 2,253,446 (+)NCBI
RefSeq Acc Id: XR_005495226
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8172,241,769 - 2,256,679 (+)NCBI
mRatBN7.2172,236,091 - 2,251,003 (+)NCBI
RefSeq Acc Id: XR_010058804
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8172,241,769 - 2,256,679 (+)NCBI
Protein Sequences
Protein RefSeqs NP_446168 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein CAA06313 (Get FASTA)   NCBI Sequence Viewer  
  EDL84406 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000023865
  ENSRNOP00000023865.2
GenBank Protein Q9Z1N1 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_446168   ⟸   NM_053716
- UniProtKB: Q9Z1N1 (UniProtKB/Swiss-Prot),   A6KQB2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000023865   ⟸   ENSRNOT00000023865
Protein Domains
Fructose-1-6-bisphosphatase class 1 C-terminal   Fructose-1-6-bisphosphatase class I N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9Z1N1-F1-model_v2 AlphaFold Q9Z1N1 1-339 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700256
Promoter ID:EPDNEW_R10779
Type:initiation region
Name:Fbp2_1
Description:fructose-bisphosphatase 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.017389,930 - 389,990EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620930 AgrOrtholog
BioCyc Gene G2FUF-10511 BioCyc
BioCyc Pathway PWY66-399 [gluconeogenesis III] BioCyc
BioCyc Pathway Image PWY66-399 BioCyc
Ensembl Genes ENSRNOG00000017637 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000023865 ENTREZGENE
  ENSRNOT00000023865.4 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.190.80 UniProtKB/Swiss-Prot
  Fructose-1,6-Bisphosphatase, subunit A, domain 1 UniProtKB/Swiss-Prot
InterPro FBPase_C_dom UniProtKB/Swiss-Prot
  FBPase_class-1 UniProtKB/Swiss-Prot
  FBPase_N UniProtKB/Swiss-Prot
  FBPtase UniProtKB/Swiss-Prot
  Fructose_bisphosphatase_AS UniProtKB/Swiss-Prot
KEGG Report rno:114508 UniProtKB/Swiss-Prot
NCBI Gene 114508 ENTREZGENE
PANTHER FRUCTOSE-1,6-BISPHOSPHATASE ISOZYME 2 UniProtKB/Swiss-Prot
  PTHR11556 UniProtKB/Swiss-Prot
Pfam FBPase UniProtKB/Swiss-Prot
  FBPase_C UniProtKB/Swiss-Prot
PhenoGen Fbp2 PhenoGen
PIRSF FBPtase UniProtKB/Swiss-Prot
  FBPtase_SBPase UniProtKB/Swiss-Prot
PRINTS F16BPHPHTASE UniProtKB/Swiss-Prot
PROSITE FBPASE UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000017637 RatGTEx
Superfamily-SCOP Carbohydrate phosphatase UniProtKB/Swiss-Prot
UniProt A6KQB2 ENTREZGENE, UniProtKB/TrEMBL
  F16P2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-02 Fbp2  fructose-bisphosphatase 2  Fbp2  fructose-1,6-bisphosphatase 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Fbp2  fructose-1,6-bisphosphatase 2    fructose bisphosphatase 2  Name updated 1299863 APPROVED
2002-08-07 Fbp2  fructose bisphosphatase 2      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_regulation enzyme activity enhanced by Mn2+ and potassium ions 708330