Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-epigallocatechin 3-gallate | increases expression | ISO | RAB3D (Homo sapiens) | 6480464 | epigallocatechin gallate results in increased expression of RAB3D protein | CTD | PMID:31195006 | 1,2-dimethylhydrazine | multiple interactions | ISO | Rab3d (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of RAB3D mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | increases expression | ISO | Rab3d (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of RAB3D mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of RAB3D mRNA | CTD | PMID:17557909 | 17beta-estradiol | multiple interactions | ISO | RAB3D (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of RAB3D mRNA | CTD | PMID:30165855 | 17beta-estradiol | decreases expression | ISO | RAB3D (Homo sapiens) | 6480464 | Estradiol results in decreased expression of RAB3D mRNA | CTD | PMID:31614463 | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of RAB3D mRNA | CTD | PMID:32145629 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Rab3d (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of RAB3D mRNA | CTD | PMID:19770486 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Rab3d (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of RAB3D mRNA | CTD | PMID:26290441 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Rab3d (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of RAB3D mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of RAB3D mRNA | CTD | PMID:21215274 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | AHR protein alternative form affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of RAB3D mRNA] | CTD | PMID:21215274 | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of RAB3D mRNA | CTD | PMID:21346803 | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 6-dinitrotoluene affects the expression of RAB3D mRNA | CTD | PMID:21346803 | 3,3',4,4',5-pentachlorobiphenyl | decreases expression | EXP | | 6480464 | 3 more ... | CTD | PMID:23196670 | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | Rab3d (Mus musculus) | 6480464 | tetrabromobisphenol A results in decreased expression of RAB3D mRNA | CTD | PMID:25172293 | 3-chloropropane-1,2-diol | decreases expression | EXP | | 6480464 | alpha-Chlorohydrin results in decreased expression of RAB3D protein | CTD | PMID:34915118 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of RAB3D mRNA | CTD | PMID:24780913 | aflatoxin B1 | decreases methylation | ISO | RAB3D (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of RAB3D intron | CTD | PMID:30157460 | all-trans-retinoic acid | increases expression | ISO | RAB3D (Homo sapiens) | 6480464 | Tretinoin results in increased expression of RAB3D mRNA | CTD | PMID:23724009 and PMID:33167477 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of RAB3D mRNA | CTD | PMID:16483693 | arsenite(3-) | multiple interactions | ISO | RAB3D (Homo sapiens) | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to RAB3D protein] | CTD | PMID:32406909 | benzo[a]pyrene | increases expression | ISO | Rab3d (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of RAB3D mRNA | CTD | PMID:19770486 | benzo[a]pyrene | affects methylation | ISO | RAB3D (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of RAB3D intron | CTD | PMID:30157460 | benzo[a]pyrene | increases methylation | ISO | RAB3D (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of RAB3D 5' UTR and Benzo(a)pyrene results in increased methylation of RAB3D promoter | CTD | PMID:27901495 | benzo[e]pyrene | increases methylation | ISO | RAB3D (Homo sapiens) | 6480464 | benzo(e)pyrene results in increased methylation of RAB3D intron | CTD | PMID:30157460 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of RAB3D mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of RAB3D mRNA | CTD | PMID:32145629 and PMID:34947998 | chloroprene | increases expression | ISO | Rab3d (Mus musculus) | 6480464 | Chloroprene results in increased expression of RAB3D mRNA | CTD | PMID:23125180 | cisplatin | increases expression | ISO | RAB3D (Homo sapiens) | 6480464 | Cisplatin results in increased expression of RAB3D mRNA | CTD | PMID:27594783 | cisplatin | multiple interactions | ISO | RAB3D (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of RAB3D mRNA | CTD | PMID:27392435 | clofibrate | multiple interactions | ISO | Rab3d (Mus musculus) | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of RAB3D mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of RAB3D mRNA] | CTD | PMID:17585979 | clofibric acid | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of RAB3D mRNA | CTD | PMID:17602206 | coumarin | increases expression | EXP | | 6480464 | coumarin results in increased expression of RAB3D mRNA | CTD | PMID:18480146 | decabromodiphenyl ether | increases expression | EXP | | 6480464 | decabromobiphenyl ether results in increased expression of RAB3D mRNA | CTD | PMID:23914054 | dexamethasone | decreases expression | EXP | | 6480464 | Dexamethasone results in decreased expression of RAB3D mRNA | CTD | PMID:20032058 | dexamethasone | increases expression | ISO | Rab3d (Mus musculus) | 6480464 | Dexamethasone results in increased expression of RAB3D mRNA | CTD | PMID:22733784 | dexamethasone | multiple interactions | EXP | | 6480464 | Testosterone inhibits the reaction [Dexamethasone results in decreased expression of RAB3D mRNA] | CTD | PMID:20032058 | dichlorine | multiple interactions | EXP | | 6480464 | [Ozone co-treated with Chlorine] results in increased expression of RAB3D mRNA | CTD | PMID:18636392 | dioxygen | multiple interactions | ISO | Rab3d (Mus musculus) | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of RAB3D mRNA and [sulforaphane affects the susceptibility to Oxygen] which affects the expression of RAB3D mRNA | CTD | PMID:30529165 | doxorubicin | decreases expression | ISO | RAB3D (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of RAB3D mRNA | CTD | PMID:29803840 | ethanol | multiple interactions | EXP | | 6480464 | [Ethanol co-treated with Dietary Fats] results in increased expression of RAB3D mRNA | CTD | PMID:21051528 | ethanol | increases expression | ISO | RAB3D (Homo sapiens) | 6480464 | Ethanol results in increased expression of RAB3D mRNA | CTD | PMID:28986285 | ethyl methanesulfonate | decreases expression | ISO | RAB3D (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in decreased expression of RAB3D mRNA | CTD | PMID:23649840 | fluoranthene | multiple interactions | ISO | Rab3d (Mus musculus) | 6480464 | [1-methylanthracene co-treated with fluoranthene] results in decreased expression of RAB3D mRNA | CTD | PMID:28329830 | folic acid | multiple interactions | ISO | Rab3d (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of RAB3D mRNA | CTD | PMID:22206623 | formaldehyde | decreases expression | EXP | | 6480464 | Formaldehyde results in decreased expression of RAB3D mRNA | CTD | PMID:12679049 | FR900359 | increases phosphorylation | ISO | RAB3D (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of RAB3D protein | CTD | PMID:37730182 | furan | increases expression | EXP | | 6480464 | furan results in increased expression of RAB3D mRNA | CTD | PMID:25539665 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of RAB3D mRNA | CTD | PMID:22061828 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of RAB3D mRNA | CTD | PMID:33387578 | hydralazine | multiple interactions | ISO | RAB3D (Homo sapiens) | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of RAB3D mRNA | CTD | PMID:17183730 | ivermectin | decreases expression | ISO | RAB3D (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of RAB3D protein | CTD | PMID:32959892 | lipopolysaccharide | decreases expression | ISO | RAB3D (Homo sapiens) | 6480464 | Lipopolysaccharides results in decreased expression of RAB3D mRNA | CTD | PMID:35811015 | lipopolysaccharide | multiple interactions | ISO | RAB3D (Homo sapiens) | 6480464 | [S-(1 more ... | CTD | PMID:35811015 | lithocholic acid | affects binding | EXP | | 6480464 | Lithocholic Acid binds to RAB3D protein | CTD | PMID:18641422 | manganese atom | decreases expression | ISO | Rab3d (Mus musculus) | 6480464 | Manganese results in decreased expression of RAB3D mRNA | CTD | PMID:23499988 | manganese(0) | decreases expression | ISO | Rab3d (Mus musculus) | 6480464 | Manganese results in decreased expression of RAB3D mRNA | CTD | PMID:23499988 | methamphetamine | decreases expression | EXP | | 6480464 | Methamphetamine results in decreased expression of RAB3D mRNA | CTD | PMID:19564919 | methamphetamine | multiple interactions | EXP | | 6480464 | [Methamphetamine co-treated with SCH 23390] results in decreased expression of RAB3D mRNA | CTD | PMID:19564919 | methapyrilene | increases methylation | ISO | RAB3D (Homo sapiens) | 6480464 | Methapyrilene results in increased methylation of RAB3D intron | CTD | PMID:30157460 | methyl methanesulfonate | decreases expression | ISO | RAB3D (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of RAB3D mRNA | CTD | PMID:23649840 | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of RAB3D mRNA | CTD | PMID:17602206 | N-nitrosodiethylamine | increases expression | ISO | Rab3d (Mus musculus) | 6480464 | Diethylnitrosamine results in increased expression of RAB3D mRNA | CTD | PMID:24535843 | nickel sulfate | increases expression | ISO | RAB3D (Homo sapiens) | 6480464 | nickel sulfate results in increased expression of RAB3D mRNA | CTD | PMID:22714537 | orphenadrine | affects expression | EXP | | 6480464 | Orphenadrine affects the expression of RAB3D mRNA | CTD | PMID:23665939 | ozone | multiple interactions | EXP | | 6480464 | [Ozone co-treated with Chlorine] results in increased expression of RAB3D mRNA | CTD | PMID:18636392 | paracetamol | multiple interactions | ISO | Rab3d (Mus musculus) | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of RAB3D mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of RAB3D mRNA] | CTD | PMID:17585979 | pentachlorophenol | increases expression | ISO | Rab3d (Mus musculus) | 6480464 | Pentachlorophenol results in increased expression of RAB3D mRNA | CTD | PMID:23892564 | perfluorooctanoic acid | increases expression | ISO | RAB3D (Homo sapiens) | 6480464 | perfluorooctanoic acid results in increased expression of RAB3D mRNA | CTD | PMID:36326898 | pirinixic acid | increases expression | ISO | Rab3d (Mus musculus) | 6480464 | pirinixic acid results in increased expression of RAB3D mRNA | CTD | PMID:18301758 and PMID:23811191 | resveratrol | increases expression | ISO | Rab3d (Mus musculus) | 6480464 | resveratrol results in increased expression of RAB3D protein | CTD | PMID:25505154 | rotenone | increases expression | ISO | Rab3d (Mus musculus) | 6480464 | Rotenone results in increased expression of RAB3D mRNA | CTD | PMID:32937126 | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | RAB3D (Homo sapiens) | 6480464 | [S-(1 more ... | CTD | PMID:35811015 | SCH 23390 | multiple interactions | EXP | | 6480464 | [Methamphetamine co-treated with SCH 23390] results in decreased expression of RAB3D mRNA | CTD | PMID:19564919 | sodium arsenite | increases expression | ISO | Rab3d (Mus musculus) | 6480464 | sodium arsenite results in increased expression of RAB3D mRNA | CTD | PMID:33145626 | sodium fluoride | increases expression | ISO | Rab3d (Mus musculus) | 6480464 | Sodium Fluoride results in increased expression of RAB3D protein | CTD | PMID:27548804 | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of RAB3D mRNA | CTD | PMID:19281266 | sulforaphane | multiple interactions | ISO | Rab3d (Mus musculus) | 6480464 | [sulforaphane affects the susceptibility to Oxygen] which affects the expression of RAB3D mRNA | CTD | PMID:30529165 | sunitinib | decreases expression | ISO | RAB3D (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of RAB3D mRNA | CTD | PMID:31533062 | testosterone | multiple interactions | EXP | | 6480464 | Testosterone inhibits the reaction [Dexamethasone results in decreased expression of RAB3D mRNA] | CTD | PMID:20032058 | tetrachloromethane | affects expression | ISO | Rab3d (Mus musculus) | 6480464 | Carbon Tetrachloride affects the expression of RAB3D mRNA | CTD | PMID:17484886 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of RAB3D mRNA | CTD | PMID:23411599 | thioacetamide | affects expression | EXP | | 6480464 | Thioacetamide affects the expression of RAB3D mRNA | CTD | PMID:34492290 | trichloroethene | affects expression | ISO | Rab3d (Mus musculus) | 6480464 | Trichloroethylene affects the expression of RAB3D mRNA | CTD | PMID:21135412 | trichostatin A | increases expression | EXP | | 6480464 | trichostatin A results in increased expression of RAB3D mRNA | CTD | PMID:23558232 | trichostatin A | increases expression | ISO | RAB3D (Homo sapiens) | 6480464 | trichostatin A results in increased expression of RAB3D mRNA | CTD | PMID:26272509 | triphenyl phosphate | increases expression | EXP | | 6480464 | triphenyl phosphate results in increased expression of RAB3D mRNA | CTD | PMID:30589522 | tungsten | decreases expression | ISO | Rab3d (Mus musculus) | 6480464 | Tungsten results in decreased expression of RAB3D mRNA | CTD | PMID:30912803 | valproic acid | multiple interactions | ISO | RAB3D (Homo sapiens) | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of RAB3D mRNA | CTD | PMID:17183730 | valproic acid | increases expression | ISO | RAB3D (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of RAB3D mRNA | CTD | PMID:23179753 and PMID:28001369 | vinclozolin | affects expression | EXP | | 6480464 | vinclozolin affects the expression of RAB3D mRNA | CTD | PMID:19015723 | |