Gene:	Ppp2r2a ( Rattus norvegicus ) protein phosphatase 2 (formerly 2A), regulatory subunit B, alpha isoform
Description:	human homolog forms a complex with cyclin G2 that may inhibit cell cycle progression
Synonyms:	protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform;  (details...)
ArrayIDs:	1369221_at; 6361662; 6464492; 1387485_a_at; 5633745; rc_AI228112_s_at; M83298_at; D14419_s_at; A_44_P304057; 5620868; 6212727; 6705054; 5986675; M83298_g_at; 6238137; 6626117; 6394204; 6562287; rc_AA819691_at; 5693700; 6271691; 5639085; 6318166; 6546605; 6359595; 5961542; 5883978;  (details...)
Gene Type:	protein-coding
Additional Data
Homologs
Homo sapiens: PPP2R2A     See the Human gene in context in:     UCSC     NCBI MapViewer
Mus musculus: Ppp2r2a     See the Mouse gene in context in:     UCSC     NCBI MapViewer
Comparative Map Data Species Symbol Map Name Chr. Position Rattus norvegicus Ppp2r2a genome assembly 3.1 15 46562545 - 46621738     Rat Celera Assembly 15 40872346 - 40931299     RGSC genome assembly v3.4 15 46546766 - 46605958     Cytogenetic 15 p12 Mus musculus Ppp2r2a Mouse genome assembly build 36.1 14 67632893 - 67691281     Cytogenetic 14 14 D1 Homo sapiens PPP2R2A human genome assembly 8 26204950 - 26284562     Human genome assembly build 36.2 8 26204951 - 26284563     Cytogenetic 8 p21.2   View comparative maps:      NCBI MapViewer
Genome
View:
Browsers:	Select a browser to viewGene (GBrowse)Gene and SNPs (GBrowse)UCSCVCMAPEnsemblNCBIECRVISTAVISTA+UCSC
Annotation
Molecular Function	Gene Ontology protein serine/threonine phosphatase activity,  protein binding,  protein phosphatase type 2A regulator activity (details...)
Biological Process	Gene Ontology response to morphine,  protein amino acid dephosphorylation,  signal transduction (details...)
Cellular Component	Gene Ontology protein phosphatase type 2A complex (details...)
External Links
Databases	DATABASE ID SOURCE SMART: WD40 IPI PROSITE: PR55_2 IPI PROSITE: PR55_1 IPI UNIPARC: UPI0000124EA3 IPI KEGG Report: rno:117104 ENTREZGENE HomoloGene Group ID: 2035 ENTREZGENE Germonline: 620919 Pfam: PP2A_B_subs_rcg IPI Pfam: PP2A_B_N IPI KEGG Pathway: 04530 ENTREZGENE InterPro: WD40_repeat-like_dom. IPI InterPro: WD40_repeat. IPI InterPro: WD40/YVTN_repeat-like_dom. IPI InterPro: PP2A_suB_N. IPI InterPro: PP2A_PR55_CS. IPI InterPro: PP2A_Bsu_A/B_central-region. IPI InterPro: PP2A_PR55. IPI Ensembl Protein: ENSRNOP00000015318 IPI IPI: IPI00326486 IPI Gene3D-CATH: WD40/YVTN_repeat-like IPI Entrez Gene: Ppp2r2a ENTREZGENE PIRSF: PP2A_PR55 IPI IMAGE_CLONE: IMAGE:7370343 IMAGE-MGC_LOAD MGC_CLONE: MGC:156605 IMAGE-MGC_LOAD UniProt: 2ABA_RAT IPI Ensembl Genes: ENSRNOG00000011158 IPI Superfamily-SCOP: WD40_like IPI PANTHER: Pp2A_PR55 IPI PRINTS: PP2APR55. IPI
Sequences	Nucleotide: CH474023 Get FASTA Search GEO Profiles Nucleotide: BC128731 Get FASTA Search GEO Profiles Nucleotide: M83298 Get FASTA Search GEO Profiles Nucleotide: NM_053999 Get FASTA Search GEO Profiles Nucleotide: D14419 Get FASTA Search GEO Profiles Nucleotide: M83297 Get FASTA Search GEO Profiles (View all 6 Nucleotide Accessions) Protein: BAA21904 Get FASTA Protein: AAA41909 Get FASTA Protein: AAI28732 Get FASTA Protein: EDL85402 Get FASTA Protein: NP_446451 Get FASTA Protein: EDL85399 Get FASTA Protein: EDL85400 Get FASTA Protein: AAA41910 Get FASTA Protein: P36876 Get FASTA Protein: EDL85401 Get FASTA (View all 10 Protein Accessions)
Clusters	UniGene: 81155
References
Curated References	6 references in RGD related to Ppp2r2a
Other References	5 other references at PubMed related to Ppp2r2a
Database Information
RGD ID	620919
History	Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference 15-DEC-08: Ppp2r2a protein phosphatase 2 (formerly 2A), regulatory subunit B, alpha isoform Ppp2r2a protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform APPROVED Nomenclature updated to reflect human and mouse nomenclature 1299863 10-SEP-04: Ppp2r2a protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform APPROVED Symbol and Name status set to approved 1299863 07-AUG-02: Ppp2r2a protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform PROVISIONAL Symbol and Name status set to provisional 70820