Mpc1 (mitochondrial pyruvate carrier 1) - Rat Genome Database

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Gene: Mpc1 (mitochondrial pyruvate carrier 1) Rattus norvegicus
Analyze
Symbol: Mpc1
Name: mitochondrial pyruvate carrier 1
RGD ID: 620902
Description: Predicted to enable pyruvate transmembrane transporter activity. Predicted to be involved in mitochondrial pyruvate transmembrane transport. Predicted to act upstream of or within acetyl-CoA biosynthetic process from pyruvate and cellular response to leukemia inhibitory factor. Predicted to be located in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in mitochondrial pyruvate carrier deficiency. Orthologous to human MPC1 (mitochondrial pyruvate carrier 1); PARTICIPATES IN citric acid cycle pathway; fructose-1,6-bisphosphatase deficiency pathway; fumaric aciduria pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: apoptosis-regulating basic protein; brain protein 44-like; Brp44l; SLC54A1; solute carrier family 54 member 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8154,985,305 - 54,996,979 (-)NCBIGRCr8
mRatBN7.2152,437,745 - 52,449,399 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl152,437,741 - 52,449,400 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx153,139,229 - 53,150,880 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0159,130,934 - 59,142,585 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0153,214,825 - 53,226,476 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0153,026,608 - 53,038,229 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl153,026,608 - 53,038,229 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0154,275,046 - 54,286,667 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4147,077,723 - 47,089,344 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1147,080,667 - 47,092,289 (-)NCBI
Celera148,200,723 - 48,212,344 (-)NCBICelera
Cytogenetic Map1q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:12865426   PMID:18614015   PMID:20439489   PMID:22628554   PMID:22628558   PMID:34481907   PMID:37030616  


Genomics

Comparative Map Data
Mpc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8154,985,305 - 54,996,979 (-)NCBIGRCr8
mRatBN7.2152,437,745 - 52,449,399 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl152,437,741 - 52,449,400 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx153,139,229 - 53,150,880 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0159,130,934 - 59,142,585 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0153,214,825 - 53,226,476 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0153,026,608 - 53,038,229 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl153,026,608 - 53,038,229 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0154,275,046 - 54,286,667 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4147,077,723 - 47,089,344 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1147,080,667 - 47,092,289 (-)NCBI
Celera148,200,723 - 48,212,344 (-)NCBICelera
Cytogenetic Map1q12NCBI
MPC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386166,364,919 - 166,382,940 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6166,364,919 - 166,383,013 (-)EnsemblGRCh38hg38GRCh38
GRCh376166,778,407 - 166,796,428 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366166,698,397 - 166,716,476 (-)NCBINCBI36Build 36hg18NCBI36
Build 346166,748,820 - 166,766,897NCBI
Celera6167,517,772 - 167,535,855 (-)NCBICelera
Cytogenetic Map6q27NCBI
HuRef6164,249,365 - 164,267,463 (-)NCBIHuRef
CHM1_16167,042,136 - 167,060,235 (-)NCBICHM1_1
T2T-CHM13v2.06167,741,850 - 167,759,859 (-)NCBIT2T-CHM13v2.0
Mpc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39178,502,590 - 8,516,499 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl178,501,736 - 8,516,493 (+)EnsemblGRCm39 Ensembl
GRCm38178,283,787 - 8,297,667 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl178,282,904 - 8,297,661 (+)EnsemblGRCm38mm10GRCm38
MGSCv37178,476,678 - 8,490,526 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36178,121,987 - 8,135,835 (+)NCBIMGSCv36mm8
Celera12112,049,395 - 112,049,996 (-)NCBICelera
Cytogenetic Map17A1NCBI
cM Map174.92NCBI
Mpc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543915,516,090 - 15,531,116 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543915,515,966 - 15,531,618 (+)NCBIChiLan1.0ChiLan1.0
MPC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25186,572,971 - 186,591,196 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16184,468,871 - 184,487,160 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06164,331,604 - 164,349,747 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16169,313,271 - 169,318,685 (-)NCBIpanpan1.1PanPan1.1panPan2
MPC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1154,379,195 - 54,395,697 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha155,167,961 - 55,184,449 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0154,557,931 - 54,574,673 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl154,557,928 - 54,574,770 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1154,455,224 - 54,471,730 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0154,304,263 - 54,320,827 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0154,928,921 - 54,945,422 (-)NCBIUU_Cfam_GSD_1.0
Mpc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946148,927,328 - 148,929,837 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648916,179,810 - 16,184,020 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648916,179,321 - 16,181,991 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MPC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.112,541,475 - 2,552,864 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213,681,075 - 3,692,480 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MPC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11394,080,417 - 94,100,149 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604065,907,418 - 65,927,150 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mpc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478512,877,077 - 12,891,914 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478512,876,942 - 12,892,417 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mpc1
18 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:123
Count of miRNA genes:98
Interacting mature miRNAs:112
Transcripts:ENSRNOT00000017282
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738020Pia8Pristane induced arthritis QTL 84.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1165833076Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
631508Sald1Serum aldosterone level QTL 13.7blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)1985600154856001Rat
2302038Pia31Pristane induced arthritis QTL 315.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)11099206555992065Rat
1300167Hrtrt2Heart rate QTL 24.35heart pumping trait (VT:2000009)heart rate (CMO:0000002)11148131275088344Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)11148131282174945Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)11148131282174945Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)11148131282174945Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)11148131282174945Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
1578756Iddm22Insulin dependent diabetes mellitus QTL 222.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)11183518156835181Rat
634353Rends2Renal damage susceptibility QTL 20.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)11933357156983283Rat
724520Bp145Blood pressure QTL 1452.10.0024arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12078482865784828Rat
1357400Bw62Body weight QTL624.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)12234064767340647Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)122340647102268831Rat
1331785Rf27Renal function QTL 274.643urine sodium amount (VT:0006274)urine sodium level (CMO:0000129)12887978078430678Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13273727390665040Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
1354599Bw29Body weight QTL 293.460.001body mass (VT:0001259)body weight (CMO:0000012)13344984878449848Rat
1354643Foco2Food consumption QTL 27.170.0001eating behavior trait (VT:0001431)food intake rate (CMO:0000427)13344984878449848Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13483685879836858Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13483685879836858Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)13483685879836858Rat
1331732Srn4Serum renin concentration QTL 44.467renin activity (VT:0005581)plasma renin activity level (CMO:0000116)13523959878430678Rat
1331792Rf29Renal function QTL 294.589urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)13523959878430678Rat
2313051Bss57Bone structure and strength QTL 573.70.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)143284731118944897Rat
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313072Bss53Bone structure and strength QTL 534.30.0001tibia length (VT:0004357)tibia length (CMO:0000450)143284731118944897Rat
2313078Bss54Bone structure and strength QTL 543.50.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313094Bss58Bone structure and strength QTL 583.70.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143284731118944897Rat
2313098Bmd70Bone mineral density QTL 703.60.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)143284731118944897Rat
2313099Bss56Bone structure and strength QTL 562.40.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143284731118944897Rat
2302059Pia36Pristane induced arthritis QTL 363.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)14333300288333002Rat
1331778Rf28Renal function QTL 284.66urine potassium amount (VT:0010539)urine potassium excretion rate (CMO:0000761)14580314078430678Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)148963584144267916Rat
4889962Bss94Bone structure and strength QTL 943.8tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)14936146582174945Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)14939317294393172Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat

Markers in Region
Brp44l  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2863,551,065 - 63,551,166 (+)MAPPERmRatBN7.2
mRatBN7.23146,409,902 - 146,410,003 (+)MAPPERmRatBN7.2
Rnor_6.03154,234,207 - 154,234,307NCBIRnor6.0
Rnor_6.0867,980,955 - 67,981,055NCBIRnor6.0
Rnor_5.0867,709,847 - 67,709,947UniSTSRnor5.0
Rnor_5.03161,367,456 - 161,367,556UniSTSRnor5.0
RGSC_v3.43148,462,655 - 148,462,755UniSTSRGSC3.4
RGSC_v3.4867,239,327 - 67,239,427UniSTSRGSC3.4
Celera862,964,830 - 62,964,930UniSTS
Celera3145,113,595 - 145,113,695UniSTS
Cytogenetic Map3q42UniSTS
Cytogenetic Map1q11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000017282   ⟹   ENSRNOP00000017282
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl152,437,755 - 52,449,400 (-)Ensembl
Rnor_6.0 Ensembl153,026,608 - 53,038,229 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000098843   ⟹   ENSRNOP00000080552
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl152,437,741 - 52,449,392 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000105772   ⟹   ENSRNOP00000080891
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl152,437,741 - 52,438,967 (-)Ensembl
RefSeq Acc Id: NM_133561   ⟹   NP_598245
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8154,985,307 - 54,996,958 (-)NCBI
mRatBN7.2152,437,747 - 52,449,399 (-)NCBI
Rnor_6.0153,026,608 - 53,038,229 (-)NCBI
Rnor_5.0154,275,046 - 54,286,667 (-)NCBI
RGSC_v3.4147,077,723 - 47,089,344 (-)RGD
Celera148,200,723 - 48,212,344 (-)RGD
Sequence:
RefSeq Acc Id: XM_039086663   ⟹   XP_038942591
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8154,985,305 - 54,989,411 (-)NCBI
mRatBN7.2152,437,745 - 52,441,856 (-)NCBI
RefSeq Acc Id: XM_063274001   ⟹   XP_063130071
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8154,985,305 - 54,988,846 (-)NCBI
RefSeq Acc Id: XM_063274062   ⟹   XP_063130132
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8154,985,305 - 54,989,434 (-)NCBI
RefSeq Acc Id: XM_063274096   ⟹   XP_063130166
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8154,985,305 - 54,996,979 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_598245   ⟸   NM_133561
- UniProtKB: Q4V8N5 (UniProtKB/Swiss-Prot),   P63031 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000017282   ⟸   ENSRNOT00000017282
RefSeq Acc Id: XP_038942591   ⟸   XM_039086663
- Peptide Label: isoform X1
- UniProtKB: A0A8L2Q8K1 (UniProtKB/TrEMBL),   A6KK31 (UniProtKB/TrEMBL),   A0A8I5ZR29 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000080552   ⟸   ENSRNOT00000098843
RefSeq Acc Id: ENSRNOP00000080891   ⟸   ENSRNOT00000105772
RefSeq Acc Id: XP_063130166   ⟸   XM_063274096
- Peptide Label: isoform X3
- UniProtKB: Q4V8N5 (UniProtKB/Swiss-Prot),   P63031 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063130132   ⟸   XM_063274062
- Peptide Label: isoform X2
- UniProtKB: A6KK36 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063130071   ⟸   XM_063274001
- Peptide Label: isoform X2
- UniProtKB: A6KK36 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P63031-F1-model_v2 AlphaFold P63031 1-109 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689629
Promoter ID:EPDNEW_R153
Type:initiation region
Name:Mpc1_1
Description:mitochondrial pyruvate carrier 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0153,038,240 - 53,038,300EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620902 AgrOrtholog
BioCyc Gene G2FUF-61511 BioCyc
Ensembl Genes ENSRNOG00000012415 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000017282.7 UniProtKB/TrEMBL
  ENSRNOT00000098843.1 UniProtKB/TrEMBL
  ENSRNOT00000105772.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7445460 IMAGE-MGC_LOAD
InterPro MPC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:171087 UniProtKB/Swiss-Prot
MGC_CLONE MGC:114268 IMAGE-MGC_LOAD
NCBI Gene 171087 ENTREZGENE
PANTHER MITOCHONDRIAL PYRUVATE CARRIER UniProtKB/TrEMBL
  MITOCHONDRIAL PYRUVATE CARRIER 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UPF0041 BRAIN PROTEIN 44-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam MPC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Mpc1 PhenoGen
RatGTEx ENSRNOG00000012415 RatGTEx
UniProt A0A8I5ZR29 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6G4P7_RAT UniProtKB/TrEMBL
  A0A8L2Q8K1 ENTREZGENE, UniProtKB/TrEMBL
  A6KK31 ENTREZGENE, UniProtKB/TrEMBL
  A6KK36 ENTREZGENE, UniProtKB/TrEMBL
  MPC1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q4V8N5 ENTREZGENE
UniProt Secondary Q4V8N5 UniProtKB/Swiss-Prot
  Q9D6C0 UniProtKB/Swiss-Prot
  Q9JLG5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-08-08 Mpc1  mitochondrial pyruvate carrier 1  Brp44l  brain protein 44-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Brp44l  brain protein 44-like      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Brp44l  brain protein 44-like      Symbol and Name status set to provisional 70820 PROVISIONAL