Mpc1 (mitochondrial pyruvate carrier 1) - Rat Genome Database

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Gene: Mpc1 (mitochondrial pyruvate carrier 1) Rattus norvegicus
Analyze
Symbol: Mpc1
Name: mitochondrial pyruvate carrier 1
RGD ID: 620902
Description: Predicted to enable pyruvate transmembrane transporter activity. Predicted to be involved in pyruvate import into mitochondria. Predicted to act upstream of or within cellular response to leukemia inhibitory factor and pyruvate decarboxylation to acetyl-CoA. Predicted to be located in membrane and mitochondrion. Predicted to be active in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in mitochondrial pyruvate carrier deficiency. Orthologous to human MPC1 (mitochondrial pyruvate carrier 1); PARTICIPATES IN citric acid cycle pathway; fructose-1,6-bisphosphatase deficiency pathway; fumaric aciduria pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: apoptosis-regulating basic protein; brain protein 44-like; Brp44l; SLC54A1; solute carrier family 54 member 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8154,985,305 - 54,996,979 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl154,985,301 - 54,997,064 (-)EnsemblGRCr8
mRatBN7.2152,437,745 - 52,449,399 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl152,437,741 - 52,449,400 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx153,139,229 - 53,150,880 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0159,130,934 - 59,142,585 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0153,214,825 - 53,226,476 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0153,026,608 - 53,038,229 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl153,026,608 - 53,038,229 (-)Ensemblrn6Rnor6.0
Rnor_5.0154,275,046 - 54,286,667 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4147,077,723 - 47,089,344 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera148,200,723 - 48,212,344 (-)NCBICelera
RGSC_v3.1147,080,667 - 47,092,289 (-)NCBI
Cytogenetic Map1q12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(+)-schisandrin B  (EXP)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2-methylcholine  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-phenylbutyric acid  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (EXP)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
azathioprine  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP)
carbamazepine  (ISO)
CGP 52608  (ISO)
chromium(6+)  (ISO)
ciglitazone  (ISO)
cobalt dichloride  (EXP)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
dicrotophos  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
flavonoids  (EXP)
folic acid  (ISO)
genistein  (EXP,ISO)
gentamycin  (EXP)
glyphosate  (ISO)
isotretinoin  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
Mesaconitine  (EXP)
methimazole  (EXP)
N-methyl-N-nitrosourea  (EXP)
nefazodone  (EXP)
ozone  (EXP)
paracetamol  (EXP,ISO)
perfluorooctanoic acid  (EXP)
phenylmercury acetate  (ISO)
pirinixic acid  (EXP,ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
progesterone  (EXP)
propofol  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
sevoflurane  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
tetrachloromethane  (EXP)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
Triptolide  (EXP)
triptonide  (ISO)
tungsten  (ISO)
tunicamycin  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:12865426   PMID:18614015   PMID:20439489   PMID:22628554   PMID:22628558   PMID:34481907   PMID:37030616   PMID:38867145  


Genomics

Comparative Map Data
Mpc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8154,985,305 - 54,996,979 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl154,985,301 - 54,997,064 (-)EnsemblGRCr8
mRatBN7.2152,437,745 - 52,449,399 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl152,437,741 - 52,449,400 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx153,139,229 - 53,150,880 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0159,130,934 - 59,142,585 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0153,214,825 - 53,226,476 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0153,026,608 - 53,038,229 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl153,026,608 - 53,038,229 (-)Ensemblrn6Rnor6.0
Rnor_5.0154,275,046 - 54,286,667 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4147,077,723 - 47,089,344 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera148,200,723 - 48,212,344 (-)NCBICelera
RGSC_v3.1147,080,667 - 47,092,289 (-)NCBI
Cytogenetic Map1q12NCBI
MPC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386166,364,919 - 166,382,940 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6166,364,919 - 166,383,013 (-)Ensemblhg38GRCh38
GRCh376166,778,407 - 166,796,428 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366166,698,397 - 166,716,476 (-)NCBIBuild 36Build 36hg18NCBI36
Build 346166,748,820 - 166,766,897NCBI
Celera6167,517,772 - 167,535,855 (-)NCBICelera
Cytogenetic Map6q27NCBI
HuRef6164,249,365 - 164,267,463 (-)NCBIHuRef
CHM1_16167,042,136 - 167,060,235 (-)NCBICHM1_1
T2T-CHM13v2.06167,741,850 - 167,759,859 (-)NCBIT2T-CHM13v2.0
Mpc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39178,502,590 - 8,516,499 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl178,501,736 - 8,516,493 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38178,283,787 - 8,297,667 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl178,282,904 - 8,297,661 (+)Ensemblmm10GRCm38
MGSCv37178,476,678 - 8,490,526 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36178,121,987 - 8,135,835 (+)NCBIMGSCv36mm8
Celera12112,049,395 - 112,049,996 (-)NCBICelera
Cytogenetic Map17A1NCBI
cM Map174.92NCBI
Mpc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543915,516,090 - 15,531,116 (+)Ensembl
ChiLan1.0NW_00495543915,515,966 - 15,531,618 (+)NCBIChiLan1.0ChiLan1.0
MPC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25186,572,971 - 186,591,196 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16184,468,871 - 184,487,160 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06164,331,604 - 164,349,747 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16169,313,271 - 169,318,685 (-)NCBIPanPan1.1PanPan1.1panPan2
MPC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1154,379,195 - 54,395,697 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha155,167,961 - 55,184,449 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0154,557,931 - 54,574,673 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl154,557,928 - 54,574,770 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1154,455,224 - 54,471,730 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0154,304,263 - 54,320,827 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0154,928,921 - 54,945,422 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Mpc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946148,927,328 - 148,929,837 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648916,179,810 - 16,184,020 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493648916,179,321 - 16,181,991 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MPC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.112,541,475 - 2,552,864 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213,681,075 - 3,692,480 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MPC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11394,080,417 - 94,100,149 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604065,907,418 - 65,927,150 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mpc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478512,877,077 - 12,891,914 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462478512,876,942 - 12,892,417 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Mpc1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v12187,151,291 - 187,163,032 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Mpc1
479 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:123
Count of miRNA genes:98
Interacting mature miRNAs:112
Transcripts:ENSRNOT00000017282
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331732Srn4Serum renin concentration QTL 44.467renin activity (VT:0005581)plasma renin activity level (CMO:0000116)14345783787558729Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)151940904101229020Rat
1357397Bw41Body weight QTL 414.190.0001body mass (VT:0001259)body weight (CMO:0000012)12940927974409279Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)14630261591302615Rat
1331792Rf29Renal function QTL 294.589urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)14345783787558729Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)14630261591302615Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)151940904168768703Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat
1354643Foco2Food consumption QTL 27.170.0001eating behavior trait (VT:0001431)food intake rate (CMO:0000427)14212296887122968Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)14630261591302615Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
1331778Rf28Renal function QTL 284.66urine potassium amount (VT:0010539)urine potassium excretion rate (CMO:0000761)14345783787558729Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)14630261591302615Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)151511344153680016Rat
1578756Iddm22Insulin dependent diabetes mellitus QTL 222.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)12050832665508326Rat
1331785Rf27Renal function QTL 274.643urine sodium amount (VT:0006274)urine sodium level (CMO:0000129)13070837587558729Rat
631508Sald1Serum aldosterone level QTL 13.7blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)11168446456684464Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13456572679565726Rat
4889962Bss94Bone structure and strength QTL 943.8tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)15190920691302615Rat
1558642Prcr2Prostate cancer resistance QTL 24.3prostate integrity trait (VT:0010571)area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)11037949255379492Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)14630261591302615Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)14350995288509952Rat
152025249Scl82Serum cholesterol level QTL 824.77blood cholesterol amount (VT:0000180)152891222109116986Rat
1354599Bw29Body weight QTL 293.460.001body mass (VT:0001259)body weight (CMO:0000012)14212296887122968Rat
2302038Pia31Pristane induced arthritis QTL 315.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)11282049457820494Rat
4889919Bss86Bone structure and strength QTL 864.1tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)14630261591302615Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat
634353Rends2Renal damage susceptibility QTL 20.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)12065642065656420Rat

Markers in Region
Brp44l  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2863,551,065 - 63,551,166 (+)MAPPERmRatBN7.2
mRatBN7.23146,409,902 - 146,410,003 (+)MAPPERmRatBN7.2
Rnor_6.03154,234,207 - 154,234,307NCBIRnor6.0
Rnor_6.0867,980,955 - 67,981,055NCBIRnor6.0
Rnor_5.0867,709,847 - 67,709,947UniSTSRnor5.0
Rnor_5.03161,367,456 - 161,367,556UniSTSRnor5.0
RGSC_v3.43148,462,655 - 148,462,755UniSTSRGSC3.4
RGSC_v3.4867,239,327 - 67,239,427UniSTSRGSC3.4
Celera862,964,830 - 62,964,930UniSTS
Celera3145,113,595 - 145,113,695UniSTS
Cytogenetic Map3q42UniSTS
Cytogenetic Map1q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000017282   ⟹   ENSRNOP00000017282
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl154,985,301 - 54,997,064 (-)Ensembl
mRatBN7.2 Ensembl152,437,755 - 52,449,400 (-)Ensembl
Rnor_6.0 Ensembl153,026,608 - 53,038,229 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000098843   ⟹   ENSRNOP00000080552
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl152,437,741 - 52,449,392 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000105772   ⟹   ENSRNOP00000080891
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl154,985,301 - 54,986,527 (-)Ensembl
mRatBN7.2 Ensembl152,437,741 - 52,438,967 (-)Ensembl
RefSeq Acc Id: NM_133561   ⟹   NP_598245
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8154,985,307 - 54,996,958 (-)NCBI
mRatBN7.2152,437,747 - 52,449,399 (-)NCBI
Rnor_6.0153,026,608 - 53,038,229 (-)NCBI
Rnor_5.0154,275,046 - 54,286,667 (-)NCBI
RGSC_v3.4147,077,723 - 47,089,344 (-)RGD
Celera148,200,723 - 48,212,344 (-)RGD
Sequence:
RefSeq Acc Id: XM_039086663   ⟹   XP_038942591
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8154,985,305 - 54,989,411 (-)NCBI
mRatBN7.2152,437,745 - 52,441,856 (-)NCBI
RefSeq Acc Id: XM_063274001   ⟹   XP_063130071
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8154,985,305 - 54,988,846 (-)NCBI
RefSeq Acc Id: XM_063274062   ⟹   XP_063130132
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8154,985,305 - 54,989,434 (-)NCBI
RefSeq Acc Id: XM_063274096   ⟹   XP_063130166
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8154,985,305 - 54,996,979 (-)NCBI
RefSeq Acc Id: NP_598245   ⟸   NM_133561
- UniProtKB: Q4V8N5 (UniProtKB/Swiss-Prot),   P63031 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSRNOP00000017282   ⟸   ENSRNOT00000017282
RefSeq Acc Id: XP_038942591   ⟸   XM_039086663
- Peptide Label: isoform X1
- UniProtKB: A0A8L2Q8K1 (UniProtKB/TrEMBL),   A6KK31 (UniProtKB/TrEMBL),   A0A8I5ZR29 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000080552   ⟸   ENSRNOT00000098843
Ensembl Acc Id: ENSRNOP00000080891   ⟸   ENSRNOT00000105772
RefSeq Acc Id: XP_063130166   ⟸   XM_063274096
- Peptide Label: isoform X3
- UniProtKB: Q4V8N5 (UniProtKB/Swiss-Prot),   P63031 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063130132   ⟸   XM_063274062
- Peptide Label: isoform X2
- UniProtKB: A6KK36 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063130071   ⟸   XM_063274001
- Peptide Label: isoform X2
- UniProtKB: A6KK36 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P63031-F1-model_v2 AlphaFold P63031 1-109 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689629
Promoter ID:EPDNEW_R153
Type:initiation region
Name:Mpc1_1
Description:mitochondrial pyruvate carrier 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0153,038,240 - 53,038,300EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620902 AgrOrtholog
BioCyc Gene G2FUF-61511 BioCyc
Ensembl Genes ENSRNOG00000012415 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000017282 ENTREZGENE
  ENSRNOT00000105772 ENTREZGENE
IMAGE_CLONE IMAGE:7445460 IMAGE-MGC_LOAD
InterPro MPC UniProtKB/Swiss-Prot
KEGG Report rno:171087 UniProtKB/Swiss-Prot
MGC_CLONE MGC:114268 IMAGE-MGC_LOAD
NCBI Gene 171087 ENTREZGENE
PANTHER UPF0041 BRAIN PROTEIN 44-RELATED UniProtKB/Swiss-Prot
Pfam MPC UniProtKB/Swiss-Prot
PhenoGen Mpc1 PhenoGen
RatGTEx ENSRNOG00000012415 RatGTEx
UniProt A0A8I5ZR29 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2Q8K1 ENTREZGENE, UniProtKB/TrEMBL
  A6KK31 ENTREZGENE, UniProtKB/TrEMBL
  A6KK36 ENTREZGENE, UniProtKB/TrEMBL
  MPC1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q4V8N5 ENTREZGENE
UniProt Secondary Q4V8N5 UniProtKB/Swiss-Prot
  Q9D6C0 UniProtKB/Swiss-Prot
  Q9JLG5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-08-08 Mpc1  mitochondrial pyruvate carrier 1  Brp44l  brain protein 44-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Brp44l  brain protein 44-like      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Brp44l  brain protein 44-like      Symbol and Name status set to provisional 70820 PROVISIONAL