B4galt1 (beta-1,4-galactosyltransferase 1) - Rat Genome Database

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Gene: B4galt1 (beta-1,4-galactosyltransferase 1) Rattus norvegicus
Analyze
Symbol: B4galt1
Name: beta-1,4-galactosyltransferase 1
RGD ID: 620900
Description: Predicted to enable several functions, including UDP-galactosyltransferase activity; manganese ion binding activity; and tubulin binding activity. Predicted to be involved in lipid metabolic process; positive regulation of circulating fibrinogen levels; and protein N-linked glycosylation. Predicted to act upstream of or within several processes, including binding activity of sperm to zona pellucida; lactose biosynthetic process; and regulation of epithelial cell proliferation. Predicted to be located in several cellular components, including Golgi trans cisterna; basolateral plasma membrane; and brush border membrane. Predicted to be part of protein-containing complex. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation and congenital disorder of glycosylation type IId. Orthologous to human B4GALT1 (beta-1,4-galactosyltransferase 1); PARTICIPATES IN galactose metabolic pathway; galactosemia pathway; Glut1 deficiency syndrome pathway; INTERACTS WITH 1-benzylpiperazine; 2-methoxyethanol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: b4Gal-T1; B4galt1_mapped; beta-1,4-GalTase 1; beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase; beta4Gal-T1; Ggtb2; Glycoprotein-4-beta-galactosyltransferase 2; N-acetyllactosamine synthase; nal synthase; neolactotriaosylceramide beta-1,4-galactosyltransferase; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 1; UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1; UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 (mapped); UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8560,731,601 - 60,778,456 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl560,731,602 - 60,778,445 (-)EnsemblGRCr8
mRatBN7.2555,935,614 - 55,982,461 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl555,935,615 - 55,982,461 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx557,902,532 - 57,949,398 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0559,721,688 - 59,768,553 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0559,715,682 - 59,762,877 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0557,121,768 - 57,168,610 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl557,121,769 - 57,168,610 (-)Ensemblrn6Rnor6.0
Rnor_5.0561,653,278 - 61,700,179 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4558,196,388 - 58,243,231 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera554,547,735 - 54,594,543 (-)NCBICelera
Cytogenetic Map5q22NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(-)-demecolcine  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
1-benzylpiperazine  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2-methoxyethanol  (EXP)
2-tert-butylhydroquinone  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (ISO)
4-nonylphenol  (ISO)
4-octylphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acetylsalicylic acid  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
ammonium chloride  (EXP)
andrographolide  (ISO)
antirheumatic drug  (ISO)
Bardoxolone methyl  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
captan  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chrysene  (ISO)
cobalt dichloride  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
coumarin  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diazinon  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
diethylstilbestrol  (ISO)
diquat  (ISO)
dopamine  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
epoxiconazole  (ISO)
estriol  (ISO)
fenoldopam  (EXP)
fenthion  (ISO)
finasteride  (EXP)
fipronil  (EXP)
folic acid  (ISO)
folpet  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
glycidyl methacrylate  (ISO)
ivermectin  (ISO)
keratan sulfate  (ISO)
lipopolysaccharide  (ISO)
lithium chloride  (ISO)
malathion  (ISO)
methapyrilene  (ISO)
methimazole  (EXP)
methotrexate  (ISO)
methoxychlor  (EXP)
methylseleninic acid  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
paracetamol  (ISO)
paricalcitol  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenylmercury acetate  (ISO)
phosphorus atom  (ISO)
phosphorus(.)  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (EXP,ISO)
Soman  (EXP)
sulfadimethoxine  (EXP)
sulforaphane  (ISO)
sulindac  (EXP)
sunitinib  (ISO)
tamoxifen  (ISO)
testosterone  (ISO)
tetraphene  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
Tributyltin oxide  (ISO)
trichloroethene  (EXP)
triphenyl phosphate  (ISO)
Triptolide  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Deficiency of UDP-galactose:N-acetylglucosamine beta-1,4-galactosyltransferase I causes the congenital disorder of glycosylation type IId. Hansske B, etal., J Clin Invest. 2002 Mar;109(6):725-33.
3. The functional interaction between CDK11p58 and beta-1,4-galactosyltransferase I involved in astrocyte activation caused by lipopolysaccharide. Liu X, etal., Inflammation. 2012 Aug;35(4):1365-77. doi: 10.1007/s10753-012-9450-9.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
9. GOA pipeline RGD automated data pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Comprehensive gene review and curation RGD comprehensive gene curation
13. Expression of beta-1,4-galactosyltransferase II and V in rat injured sciatic nerves. Shen A, etal., Neurosci Lett 2002 Jul 12;327(1):45-8.
Additional References at PubMed
PMID:33805   PMID:1302270   PMID:2120039   PMID:2503706   PMID:3917437   PMID:6121819   PMID:7641815   PMID:7744867   PMID:8089187   PMID:8134355   PMID:8787759   PMID:8889548  
PMID:9013935   PMID:9155011   PMID:9374408   PMID:9588205   PMID:9813328   PMID:10381349   PMID:10900002   PMID:11375348   PMID:11419947   PMID:11463354   PMID:11900463   PMID:12714507  
PMID:15039218   PMID:15158676   PMID:15282149   PMID:16157350   PMID:16502470   PMID:17372842   PMID:17917074   PMID:18294815   PMID:18320333   PMID:18512149   PMID:18677561   PMID:19056867  
PMID:19199708   PMID:19530228   PMID:19946888   PMID:21161318   PMID:21461672   PMID:21573722   PMID:22359038   PMID:22687727   PMID:22706684   PMID:23376485   PMID:23533145   PMID:24006456  


Genomics

Comparative Map Data
B4galt1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8560,731,601 - 60,778,456 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl560,731,602 - 60,778,445 (-)EnsemblGRCr8
mRatBN7.2555,935,614 - 55,982,461 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl555,935,615 - 55,982,461 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx557,902,532 - 57,949,398 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0559,721,688 - 59,768,553 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0559,715,682 - 59,762,877 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0557,121,768 - 57,168,610 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl557,121,769 - 57,168,610 (-)Ensemblrn6Rnor6.0
Rnor_5.0561,653,278 - 61,700,179 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4558,196,388 - 58,243,231 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera554,547,735 - 54,594,543 (-)NCBICelera
Cytogenetic Map5q22NCBI
B4GALT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38933,104,077 - 33,185,089 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl933,100,493 - 33,167,359 (-)Ensemblhg38GRCh38
GRCh37933,104,075 - 33,167,334 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36933,100,642 - 33,157,236 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34933,100,641 - 33,157,231NCBI
Celera933,041,647 - 33,098,362 (-)NCBICelera
Cytogenetic Map9p21.1NCBI
HuRef933,068,632 - 33,125,120 (-)NCBIHuRef
CHM1_1933,110,422 - 33,167,124 (-)NCBICHM1_1
T2T-CHM13v2.0933,120,636 - 33,185,969 (-)NCBIT2T-CHM13v2.0
B4galt1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39440,804,602 - 40,855,711 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl440,804,602 - 40,854,005 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38440,804,602 - 40,853,984 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl440,804,602 - 40,854,005 (-)Ensemblmm10GRCm38
MGSCv37440,751,635 - 40,801,031 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36440,993,273 - 41,042,669 (-)NCBIMGSCv36mm8
Celera440,465,334 - 40,514,995 (-)NCBICelera
Cytogenetic Map4A5NCBI
cM Map420.46NCBI
B4galt1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554722,490,661 - 2,536,317 (+)Ensembl
ChiLan1.0NW_0049554722,490,649 - 2,536,053 (+)NCBIChiLan1.0ChiLan1.0
B4GALT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21191,435,685 - 91,492,756 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1991,441,627 - 91,498,698 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0932,889,124 - 32,945,759 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1933,697,551 - 33,754,192 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl933,691,733 - 33,754,192 (-)EnsemblpanPan2panpan1.1
B4GALT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11150,223,880 - 50,276,745 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1150,226,242 - 50,276,730 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1148,852,300 - 48,904,681 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01151,162,293 - 51,214,628 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1151,144,069 - 51,214,773 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11149,827,305 - 49,879,364 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01149,693,975 - 49,746,100 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01150,459,162 - 50,511,219 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
B4galt1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947165,112,211 - 165,166,434 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365241,659,608 - 1,714,102 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365241,659,791 - 1,713,971 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
B4GALT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1033,317,305 - 33,381,285 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11033,317,295 - 33,381,285 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21037,574,201 - 37,635,284 (+)NCBISscrofa10.2Sscrofa10.2susScr3
B4GALT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11247,104,750 - 47,162,157 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1247,104,789 - 47,162,173 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366703211,002 - 21,137 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
B4galt1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473637,848,117 - 37,927,980 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473637,848,431 - 37,927,291 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
B4galt1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11117,330,343 - 117,380,818 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in B4galt1
402 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:129
Count of miRNA genes:100
Interacting mature miRNAs:114
Transcripts:ENSRNOT00000010874
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)53275164977751649Rat
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53801167083011670Rat
1300115Hrtrt7Heart rate QTL 72.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)55266537294894052Rat
6907115Mcs29Mammary carcinoma susceptibility QTL 29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)53800433183004331Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)544924861153890773Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)52367149379046465Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)538207390136631402Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51757663362576633Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)548523123134369373Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53801167083011670Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53801167083011670Rat
1331782Rf36Renal function QTL 363.296kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)539019942102105896Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)53331167378311673Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)53275164977751649Rat
1641922Alcrsp8Alcohol response QTL 8alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)51748608062486080Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)53998594884985948Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)5692228281330203Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53331167378311673Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)53952692484526924Rat
1331773Scl26Serum cholesterol level QTL 263.065blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)54852312391770353Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)560601597137492949Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906491770353Rat
61359EaexExperimental allergic encephalomyelitis QTL x3nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)560511627105511627Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5706553574335773Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)536460764136631402Rat
1641903Alcrsp3Alcohol response QTL 3response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)51748608062486080Rat
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906487027358Rat
8552954Pigfal14Plasma insulin-like growth factor 1 level QTL 149blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)52602321171023211Rat
2303577Gluco47Glucose level QTL 473blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51652001961520019Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)556546393101546393Rat
1600358Mamtr5Mammary tumor resistance QTL 5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)52367149368671493Rat

Markers in Region
D5Mit1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2555,962,278 - 55,962,414 (+)MAPPERmRatBN7.2
Rnor_6.0557,148,431 - 57,148,566NCBIRnor6.0
Rnor_5.0561,679,937 - 61,680,072UniSTSRnor5.0
RGSC_v3.4558,223,050 - 58,223,186RGDRGSC3.4
RGSC_v3.4558,223,051 - 58,223,186UniSTSRGSC3.4
Celera554,574,374 - 54,574,509UniSTS
RGSC_v3.1558,223,098 - 58,223,440RGD
RH 2.0 Map5353.9RGD
Cytogenetic Map5q22UniSTS
AU046353  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2555,978,678 - 55,978,876 (+)MAPPERmRatBN7.2
Rnor_6.0557,164,828 - 57,165,025NCBIRnor6.0
Rnor_5.0561,696,335 - 61,696,532UniSTSRnor5.0
RGSC_v3.4558,239,449 - 58,239,646UniSTSRGSC3.4
Celera554,590,761 - 54,590,958UniSTS
Cytogenetic Map5q22UniSTS
RH142957  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2555,935,638 - 55,935,800 (+)MAPPERmRatBN7.2
Rnor_6.0557,121,793 - 57,121,954NCBIRnor6.0
Rnor_5.0561,653,299 - 61,653,460UniSTSRnor5.0
Rnor_5.0561,653,151 - 61,653,460UniSTSRnor5.0
RGSC_v3.4558,196,413 - 58,196,574UniSTSRGSC3.4
Celera554,547,760 - 54,547,921UniSTS
RH 3.4 Map5287.5UniSTS
Cytogenetic Map5q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000090499   ⟹   ENSRNOP00000069825
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl560,731,602 - 60,778,445 (-)Ensembl
mRatBN7.2 Ensembl555,935,615 - 55,982,461 (-)Ensembl
Rnor_6.0 Ensembl557,121,769 - 57,168,610 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000112021   ⟹   ENSRNOP00000086535
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl560,734,789 - 60,778,445 (-)Ensembl
mRatBN7.2 Ensembl555,938,802 - 55,982,461 (-)Ensembl
RefSeq Acc Id: NM_053287   ⟹   NP_445739
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8560,731,601 - 60,778,445 (-)NCBI
mRatBN7.2555,935,614 - 55,982,461 (-)NCBI
Rnor_6.0557,121,768 - 57,168,610 (-)NCBI
Rnor_5.0561,653,278 - 61,700,179 (-)NCBI
RGSC_v3.4558,196,388 - 58,243,231 (-)RGD
Celera554,547,735 - 54,594,543 (-)RGD
Sequence:
RefSeq Acc Id: XM_039109259   ⟹   XP_038965187
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8560,743,307 - 60,778,456 (-)NCBI
mRatBN7.2555,947,321 - 55,982,461 (-)NCBI
Protein Sequences
Protein RefSeqs NP_445739 (Get FASTA)   NCBI Sequence Viewer  
  XP_038965187 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAD41721 (Get FASTA)   NCBI Sequence Viewer  
  EDL98643 (Get FASTA)   NCBI Sequence Viewer  
  EDL98644 (Get FASTA)   NCBI Sequence Viewer  
  EDL98645 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000069825
GenBank Protein P80225 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_445739   ⟸   NM_053287
- UniProtKB: G3V722 (UniProtKB/TrEMBL),   A6IIS4 (UniProtKB/TrEMBL),   A6IIS3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000069825   ⟸   ENSRNOT00000090499
RefSeq Acc Id: XP_038965187   ⟸   XM_039109259
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000086535   ⟸   ENSRNOT00000112021
Protein Domains
Galactosyltransferase C-terminal   Galactosyltransferase N-terminal

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693637
Promoter ID:EPDNEW_R4161
Type:multiple initiation site
Name:B4galt1_1
Description:beta-1,4-galactosyltransferase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0557,168,585 - 57,168,645EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620900 AgrOrtholog
BioCyc Gene G2FUF-41586 BioCyc
Ensembl Genes ENSRNOG00000059461 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000090499 ENTREZGENE
NCBI Gene 24390 ENTREZGENE
PhenoGen B4galt1 PhenoGen
RatGTEx ENSRNOG00000059461 RatGTEx
UniProt A0A8I6A607_RAT UniProtKB/TrEMBL
  A6IIS3 ENTREZGENE, UniProtKB/TrEMBL
  A6IIS4 ENTREZGENE, UniProtKB/TrEMBL
  B4GT1_RAT UniProtKB/Swiss-Prot
  G3V722 ENTREZGENE, UniProtKB/TrEMBL
  P80225 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-22 B4galt1  beta-1,4-galactosyltransferase 1  B4galt1  UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 B4galt1  UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1  B4galt1_predicted  UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1  'predicted' is removed 2292626 APPROVED
2007-04-13 B4galt1_predicted  UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1  B4galt1_mapped  UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 (mapped)  Symbol and Name updated 737654 APPROVED
2007-02-02 B4galt1_mapped  UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 (mapped)  B4galt1  UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 (mapped)  Data merged from RGD:1587392 737654 APPROVED
2006-11-19 B4galt1  UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 (mapped)      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-11-17 B4galt1_mapped  UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 (mapped)      Symbol and Name updated 1556543 APPROVED
2003-04-09 B4galt1  UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1      Symbol and Name updated 629477 APPROVED
2003-03-07 B4galt1  UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1  Ggtb2  Glycoprotein-4-beta-galactosyltransferase 2  Data merged from RGD:2685 628472 PROVISIONAL
2002-08-07 B4galt1        Symbol and Name status set to provisional 70820 PROVISIONAL
2002-06-10 Ggtb2  Glycoprotein-4-beta-galactosyltransferase 2      Symbol and Name status set to approved 70586 APPROVED