Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Fxyd3 | Rat | 17alpha-ethynylestradiol | increases expression | ISO | Fxyd3 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of FXYD3 mRNA | CTD | PMID:17942748 | Fxyd3 | Rat | 17alpha-ethynylestradiol | multiple interactions | ISO | Fxyd3 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of FXYD3 mRNA | CTD | PMID:17942748 | Fxyd3 | Rat | 17beta-estradiol | affects expression | ISO | Fxyd3 (Mus musculus) | 6480464 | Estradiol affects the expression of FXYD3 mRNA | CTD | PMID:15598610 | Fxyd3 | Rat | 17beta-estradiol | multiple interactions | EXP | | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of FXYD3 mRNA | CTD | PMID:32741896 | Fxyd3 | Rat | 17beta-estradiol | increases expression | ISO | Fxyd3 (Mus musculus) | 6480464 | Estradiol results in increased expression of FXYD3 mRNA | CTD | PMID:15289156|PMID:19484750 | Fxyd3 | Rat | 17beta-estradiol | decreases expression | ISO | FXYD3 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of FXYD3 mRNA | CTD | PMID:24758408 | Fxyd3 | Rat | 17beta-estradiol | multiple interactions | ISO | FXYD3 (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of FXYD3 mRNA; EGF protein promotes more ... | CTD | PMID:24758408|PMID:30165855 | Fxyd3 | Rat | 17beta-estradiol 3-benzoate | multiple interactions | EXP | | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of FXYD3 mRNA | CTD | PMID:32741896 | Fxyd3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Fxyd3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of FXYD3 mRNA | CTD | PMID:17942748 | Fxyd3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of FXYD3 mRNA | CTD | PMID:33387578 | Fxyd3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of FXYD3 mRNA | CTD | PMID:32109520 | Fxyd3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Fxyd3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of FXYD3 mRNA | CTD | PMID:21570461 | Fxyd3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Fxyd3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of FXYD3 mRNA | CTD | PMID:21354282 | Fxyd3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Fxyd3 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of FXYD3 mRNA | CTD | PMID:17942748 | Fxyd3 | Rat | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | affects expression | ISO | Fxyd3 (Mus musculus) | 6480464 | 2,2',4,4',5-brominated diphenyl ether affects the expression of FXYD3 mRNA | CTD | PMID:38648751 | Fxyd3 | Rat | 4,4'-sulfonyldiphenol | decreases methylation | ISO | FXYD3 (Homo sapiens) | 6480464 | bisphenol S results in decreased methylation of FXYD3 gene | CTD | PMID:31601247 | Fxyd3 | Rat | 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one | multiple interactions | ISO | FXYD3 (Homo sapiens) | 6480464 | [Benzo(a)pyrene co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of FXYD3 mRNA | CTD | PMID:20146248 | Fxyd3 | Rat | 4-hydroxyphenyl retinamide | decreases expression | ISO | Fxyd3 (Mus musculus) | 6480464 | Fenretinide results in decreased expression of FXYD3 mRNA | CTD | PMID:28973697 | Fxyd3 | Rat | 5-fluorouracil | increases expression | ISO | FXYD3 (Homo sapiens) | 6480464 | Fluorouracil results in increased expression of FXYD3 mRNA | CTD | PMID:15152939 | Fxyd3 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of FXYD3 mRNA | CTD | PMID:24780913|PMID:30047161 | Fxyd3 | Rat | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of FXYD3 mRNA | CTD | PMID:31881176 | Fxyd3 | Rat | actinomycin D | multiple interactions | ISO | FXYD3 (Homo sapiens) | 6480464 | [Dactinomycin co-treated with nutlin 3] results in increased expression of FXYD3 mRNA | CTD | PMID:38460933 | Fxyd3 | Rat | actinomycin D | increases expression | ISO | FXYD3 (Homo sapiens) | 6480464 | Dactinomycin results in increased expression of FXYD3 mRNA | CTD | PMID:38460933 | Fxyd3 | Rat | aflatoxin B1 | increases expression | ISO | FXYD3 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of FXYD3 mRNA | CTD | PMID:22100608|PMID:32234424 | Fxyd3 | Rat | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of FXYD3 mRNA | CTD | PMID:22484513|PMID:23630614 | Fxyd3 | Rat | all-trans-retinoic acid | affects expression | ISO | FXYD3 (Homo sapiens) | 6480464 | Tretinoin affects the expression of FXYD3 mRNA | CTD | PMID:31600526 | Fxyd3 | Rat | all-trans-retinoic acid | multiple interactions | ISO | Fxyd3 (Mus musculus) | 6480464 | [bisphenol F co-treated with Tretinoin] results in decreased expression of FXYD3 mRNA | CTD | PMID:30951980 | Fxyd3 | Rat | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of FXYD3 mRNA | CTD | PMID:30047161 | Fxyd3 | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of FXYD3 mRNA | CTD | PMID:16483693 | Fxyd3 | Rat | amphotericin B | increases expression | ISO | FXYD3 (Homo sapiens) | 6480464 | Amphotericin B analog results in increased expression of FXYD3 mRNA | CTD | PMID:28534445 | Fxyd3 | Rat | Azoxymethane | multiple interactions | ISO | Fxyd3 (Mus musculus) | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of FXYD3 more ... | CTD | PMID:29950665 | Fxyd3 | Rat | benzo[a]pyrene | multiple interactions | ISO | FXYD3 (Homo sapiens) | 6480464 | [Benzo(a)pyrene co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of FXYD3 mRNA | CTD | PMID:20146248 | Fxyd3 | Rat | benzo[a]pyrene | increases expression | ISO | FXYD3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of FXYD3 mRNA | CTD | PMID:32234424 | Fxyd3 | Rat | benzo[a]pyrene | affects methylation | ISO | FXYD3 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of FXYD3 3' UTR | CTD | PMID:27901495 | Fxyd3 | Rat | benzo[a]pyrene | decreases methylation | ISO | FXYD3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of FXYD3 5' UTR; Benzo(a)pyrene results in decreased methylation of more ... | CTD | PMID:27901495 | Fxyd3 | Rat | benzo[a]pyrene | multiple interactions | ISO | Fxyd3 (Mus musculus) | 6480464 | AHR protein affects the reaction [Benzo(a)pyrene affects the expression of FXYD3 mRNA] | CTD | PMID:22228805 | Fxyd3 | Rat | benzo[a]pyrene | decreases expression | ISO | Fxyd3 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of FXYD3 mRNA | CTD | PMID:22228805 | Fxyd3 | Rat | bisphenol A | decreases expression | ISO | Fxyd3 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of FXYD3 mRNA | CTD | PMID:26063408 | Fxyd3 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of FXYD3 mRNA | CTD | PMID:36779543 | Fxyd3 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of FXYD3 mRNA | CTD | PMID:25181051|PMID:33296240 | Fxyd3 | Rat | bisphenol F | multiple interactions | ISO | Fxyd3 (Mus musculus) | 6480464 | [bisphenol F co-treated with Tretinoin] results in decreased expression of FXYD3 mRNA | CTD | PMID:30951980 | Fxyd3 | Rat | bisphenol F | decreases expression | ISO | Fxyd3 (Mus musculus) | 6480464 | bisphenol F results in decreased expression of FXYD3 mRNA | CTD | PMID:38685157 | Fxyd3 | Rat | bisphenol F | increases expression | ISO | Fxyd3 (Mus musculus) | 6480464 | bisphenol F results in increased expression of FXYD3 mRNA | CTD | PMID:30951980 | Fxyd3 | Rat | cadmium dichloride | increases expression | ISO | FXYD3 (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of FXYD3 mRNA | CTD | PMID:26472689 | Fxyd3 | Rat | cadmium dichloride | decreases expression | ISO | FXYD3 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of FXYD3 mRNA | CTD | PMID:38382870 | Fxyd3 | Rat | caffeine | increases phosphorylation | ISO | FXYD3 (Homo sapiens) | 6480464 | Caffeine results in increased phosphorylation of FXYD3 protein | CTD | PMID:35688186 | Fxyd3 | Rat | calcitriol | multiple interactions | ISO | FXYD3 (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in increased expression of FXYD3 mRNA | CTD | PMID:21592394 | Fxyd3 | Rat | calcitriol | increases expression | ISO | FXYD3 (Homo sapiens) | 6480464 | Calcitriol results in increased expression of FXYD3 mRNA | CTD | PMID:21592394|PMID:26485663 | Fxyd3 | Rat | camptothecin | increases expression | ISO | FXYD3 (Homo sapiens) | 6480464 | Camptothecin results in increased expression of FXYD3 mRNA | CTD | PMID:38460933 | Fxyd3 | Rat | choline | multiple interactions | ISO | Fxyd3 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression more ... | CTD | PMID:20938992 | Fxyd3 | Rat | chrysene | increases expression | ISO | Fxyd3 (Mus musculus) | 6480464 | chrysene results in increased expression of FXYD3 mRNA | CTD | PMID:26377693 | Fxyd3 | Rat | cisplatin | multiple interactions | ISO | FXYD3 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of FXYD3 mRNA | CTD | PMID:27392435 | Fxyd3 | Rat | cisplatin | increases expression | ISO | FXYD3 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of FXYD3 mRNA | CTD | PMID:27392435 | Fxyd3 | Rat | cobalt dichloride | decreases expression | EXP | | 6480464 | cobaltous chloride results in decreased expression of FXYD3 mRNA | CTD | PMID:24386269 | Fxyd3 | Rat | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of FXYD3 mRNA | CTD | PMID:26577399|PMID:27523638 | Fxyd3 | Rat | dextran sulfate | multiple interactions | ISO | Fxyd3 (Mus musculus) | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of FXYD3 more ... | CTD | PMID:29950665 | Fxyd3 | Rat | diethyl phthalate | decreases expression | EXP | | 6480464 | diethyl phthalate results in decreased expression of FXYD3 mRNA | CTD | PMID:32341500 | Fxyd3 | Rat | diethylstilbestrol | increases expression | ISO | Fxyd3 (Mus musculus) | 6480464 | Diethylstilbestrol results in increased expression of FXYD3 mRNA | CTD | PMID:15289156 | Fxyd3 | Rat | diethylstilbestrol | increases expression | EXP | | 6480464 | Diethylstilbestrol results in increased expression of FXYD3 mRNA | CTD | PMID:36653537 | Fxyd3 | Rat | diuron | increases expression | EXP | | 6480464 | Diuron results in increased expression of FXYD3 mRNA | CTD | PMID:21551480 | Fxyd3 | Rat | folic acid | multiple interactions | ISO | Fxyd3 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression more ... | CTD | PMID:20938992 | Fxyd3 | Rat | furan | increases expression | EXP | | 6480464 | furan results in increased expression of FXYD3 mRNA | CTD | PMID:27387713 | Fxyd3 | Rat | gemcitabine | increases expression | ISO | FXYD3 (Homo sapiens) | 6480464 | Gemcitabine results in increased expression of FXYD3 mRNA | CTD | PMID:17039268 | Fxyd3 | Rat | genistein | increases expression | ISO | Fxyd3 (Mus musculus) | 6480464 | Genistein results in increased expression of FXYD3 mRNA | CTD | PMID:15289156 | Fxyd3 | Rat | genistein | decreases expression | ISO | Fxyd3 (Mus musculus) | 6480464 | Genistein results in decreased expression of FXYD3 mRNA | CTD | PMID:32186404 | Fxyd3 | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of FXYD3 mRNA | CTD | PMID:33387578 | Fxyd3 | Rat | ICI D1694 | increases expression | ISO | FXYD3 (Homo sapiens) | 6480464 | raltitrexed results in increased expression of FXYD3 mRNA | CTD | PMID:15152939 | Fxyd3 | Rat | indole-3-methanol | affects expression | EXP | | 6480464 | indole-3-carbinol affects the expression of FXYD3 mRNA | CTD | PMID:21396975 | Fxyd3 | Rat | irinotecan | increases expression | ISO | FXYD3 (Homo sapiens) | 6480464 | Irinotecan results in increased expression of FXYD3 mRNA | CTD | PMID:15152939 | Fxyd3 | Rat | L-methionine | multiple interactions | ISO | Fxyd3 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression more ... | CTD | PMID:20938992 | Fxyd3 | Rat | medroxyprogesterone acetate | increases expression | ISO | FXYD3 (Homo sapiens) | 6480464 | Medroxyprogesterone Acetate results in increased expression of FXYD3 mRNA | CTD | PMID:18497975 | Fxyd3 | Rat | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of FXYD3 mRNA | CTD | PMID:30047161 | Fxyd3 | Rat | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of FXYD3 mRNA | CTD | PMID:28943392 | Fxyd3 | Rat | nickel atom | multiple interactions | ISO | FXYD3 (Homo sapiens) | 6480464 | trichostatin A inhibits the reaction [Nickel affects the expression of FXYD3 mRNA] | CTD | PMID:14575637 | Fxyd3 | Rat | nickel atom | affects expression | ISO | FXYD3 (Homo sapiens) | 6480464 | Nickel affects the expression of FXYD3 mRNA | CTD | PMID:14575637 | Fxyd3 | Rat | Nutlin-3 | multiple interactions | ISO | FXYD3 (Homo sapiens) | 6480464 | [Dactinomycin co-treated with nutlin 3] results in increased expression of FXYD3 mRNA | CTD | PMID:38460933 | Fxyd3 | Rat | okadaic acid | decreases expression | ISO | FXYD3 (Homo sapiens) | 6480464 | Okadaic Acid results in decreased expression of FXYD3 mRNA | CTD | PMID:38832940 | Fxyd3 | Rat | oxaliplatin | increases expression | ISO | FXYD3 (Homo sapiens) | 6480464 | oxaliplatin results in increased expression of FXYD3 mRNA | CTD | PMID:15152939 | Fxyd3 | Rat | ozone | multiple interactions | ISO | Fxyd3 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased more ... | CTD | PMID:34911549 | Fxyd3 | Rat | paclitaxel | increases response to substance | ISO | FXYD3 (Homo sapiens) | 6480464 | FXYD3 mRNA results in increased susceptibility to Paclitaxel | CTD | PMID:16322897 | Fxyd3 | Rat | paclitaxel | decreases expression | ISO | FXYD3 (Homo sapiens) | 6480464 | Paclitaxel results in decreased expression of FXYD3 mRNA | CTD | PMID:19682730 | Fxyd3 | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of FXYD3 mRNA | CTD | PMID:33387578 | Fxyd3 | Rat | paraquat | decreases expression | EXP | | 6480464 | Paraquat results in decreased expression of FXYD3 mRNA | CTD | PMID:32680482 | Fxyd3 | Rat | poly(I:C) | multiple interactions | EXP | | 6480464 | [Poly I-C co-treated with HU 211] results in increased expression of FXYD3 mRNA | CTD | PMID:26923065 | Fxyd3 | Rat | progesterone | increases expression | ISO | FXYD3 (Homo sapiens) | 6480464 | Progesterone results in increased expression of FXYD3 mRNA | CTD | PMID:18497975 | Fxyd3 | Rat | rotenone | increases expression | EXP | | 6480464 | Rotenone results in increased expression of FXYD3 mRNA | CTD | PMID:19013527 | Fxyd3 | Rat | S-nitrosoglutathione | decreases expression | ISO | FXYD3 (Homo sapiens) | 6480464 | S-Nitrosoglutathione results in decreased expression of FXYD3 mRNA | CTD | PMID:38825487 | Fxyd3 | Rat | silicon dioxide | increases expression | EXP | | 6480464 | Silicon Dioxide results in increased expression of FXYD3 mRNA | CTD | PMID:22431001 | Fxyd3 | Rat | sodium arsenite | decreases expression | ISO | FXYD3 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of FXYD3 mRNA | CTD | PMID:38568856 | Fxyd3 | Rat | sulfadimethoxine | decreases expression | EXP | | 6480464 | Sulfadimethoxine results in decreased expression of FXYD3 mRNA | CTD | PMID:30047161 | Fxyd3 | Rat | testosterone | multiple interactions | ISO | FXYD3 (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in increased expression of FXYD3 mRNA | CTD | PMID:21592394 | Fxyd3 | Rat | testosterone | multiple interactions | EXP | | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of FXYD3 mRNA | CTD | PMID:32741896 | Fxyd3 | Rat | testosterone | increases expression | ISO | FXYD3 (Homo sapiens) | 6480464 | Testosterone results in increased expression of FXYD3 mRNA | CTD | PMID:21592394 | Fxyd3 | Rat | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of FXYD3 mRNA | CTD | PMID:33387578 | Fxyd3 | Rat | thioacetamide | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of FXYD3 mRNA | CTD | PMID:28943392 | Fxyd3 | Rat | titanium dioxide | multiple interactions | ISO | Fxyd3 (Mus musculus) | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of FXYD3 more ... | CTD | PMID:29950665 | Fxyd3 | Rat | titanium dioxide | decreases expression | ISO | Fxyd3 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of FXYD3 mRNA | CTD | PMID:35295148 | Fxyd3 | Rat | toluene | decreases expression | EXP | | 6480464 | Toluene results in decreased expression of FXYD3 mRNA | CTD | PMID:22967744 | Fxyd3 | Rat | trichostatin A | multiple interactions | ISO | FXYD3 (Homo sapiens) | 6480464 | trichostatin A inhibits the reaction [Nickel affects the expression of FXYD3 mRNA] | CTD | PMID:14575637 | Fxyd3 | Rat | trichostatin A | increases expression | ISO | FXYD3 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of FXYD3 mRNA | CTD | PMID:24935251 | Fxyd3 | Rat | valproic acid | increases expression | ISO | FXYD3 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of FXYD3 mRNA | CTD | PMID:24935251 | Fxyd3 | Rat | valproic acid | increases expression | EXP | | 6480464 | Valproic Acid results in increased expression of FXYD3 mRNA | CTD | PMID:29427782 | Fxyd3 | Rat | vinclozolin | affects expression | EXP | | 6480464 | vinclozolin affects the expression of FXYD3 mRNA | CTD | PMID:19015723 | |






















