Kremen1 (kringle containing transmembrane protein 1) - Rat Genome Database

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Gene: Kremen1 (kringle containing transmembrane protein 1) Rattus norvegicus
Analyze
Symbol: Kremen1
Name: kringle containing transmembrane protein 1
RGD ID: 620789
Description: Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in several processes, including negative regulation of axon regeneration; negative regulation of canonical Wnt signaling pathway; and negative regulation of ossification. Predicted to be located in neuronal cell body. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in ectodermal dysplasia 13. Orthologous to human KREMEN1 (kringle containing transmembrane protein 1); PARTICIPATES IN Wnt signaling, canonical pathway; INTERACTS WITH 6-propyl-2-thiouracil; amitrole; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: dickkopf receptor; Kremen; kremen protein 1; kringle containing transmembrane protein; kringle domain-containing transmembrane protein 1; kringle-coding gene marking the eye and the nose; kringle-containing protein marking the eye and the nose
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81484,295,931 - 84,361,534 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1484,297,700 - 84,361,614 (-)EnsemblGRCr8
mRatBN7.21480,081,870 - 80,147,489 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1480,084,403 - 80,147,516 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1484,486,512 - 84,548,999 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01485,726,601 - 85,789,092 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01482,175,948 - 82,238,427 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01485,441,209 - 85,503,661 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1485,438,707 - 85,484,275 (-)Ensemblrn6Rnor6.0
Rnor_5.01486,114,543 - 86,175,894 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41485,845,443 - 85,909,575 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1478,972,429 - 79,034,890 (-)NCBICelera
RGSC_v3.11485,864,587 - 85,928,720 (-)NCBI
Cytogenetic Map14q21NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IEA)
neuronal cell body  (IEA,ISO)
plasma membrane  (IBA,IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Molecular cloning and characterization of Kremen, a novel kringle-containing transmembrane protein. Nakamura T, etal., Biochim Biophys Acta 2001 Mar 19;1518(1-2):63-72.
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. Function and biological roles of the Dickkopf family of Wnt modulators. Niehrs C Oncogene. 2006 Dec 4;25(57):7469-81.
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:18505822   PMID:24167472   PMID:26206087  


Genomics

Comparative Map Data
Kremen1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81484,295,931 - 84,361,534 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1484,297,700 - 84,361,614 (-)EnsemblGRCr8
mRatBN7.21480,081,870 - 80,147,489 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1480,084,403 - 80,147,516 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1484,486,512 - 84,548,999 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01485,726,601 - 85,789,092 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01482,175,948 - 82,238,427 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01485,441,209 - 85,503,661 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1485,438,707 - 85,484,275 (-)Ensemblrn6Rnor6.0
Rnor_5.01486,114,543 - 86,175,894 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41485,845,443 - 85,909,575 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1478,972,429 - 79,034,890 (-)NCBICelera
RGSC_v3.11485,864,587 - 85,928,720 (-)NCBI
Cytogenetic Map14q21NCBI
KREMEN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382229,073,035 - 29,168,333 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2229,072,950 - 29,168,333 (+)Ensemblhg38GRCh38
GRCh372229,469,023 - 29,564,321 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362227,799,106 - 27,872,808 (+)NCBIBuild 36Build 36hg18NCBI36
Build 342227,793,659 - 27,863,040NCBI
Celera2213,268,961 - 13,364,205 (+)NCBICelera
Cytogenetic Map22q12.1NCBI
HuRef2212,431,878 - 12,528,398 (+)NCBIHuRef
CHM1_12229,428,225 - 29,523,454 (+)NCBICHM1_1
T2T-CHM13v2.02229,534,263 - 29,631,831 (+)NCBIT2T-CHM13v2.0
Kremen1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39115,141,551 - 5,212,220 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl115,141,552 - 5,211,558 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38115,191,551 - 5,261,713 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl115,191,552 - 5,261,558 (-)Ensemblmm10GRCm38
MGSCv37115,091,555 - 5,161,613 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36115,091,555 - 5,161,613 (-)NCBIMGSCv36mm8
Celera115,691,158 - 5,761,052 (-)NCBICelera
Cytogenetic Map11A1NCBI
cM Map113.36NCBI
Kremen1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554553,320,346 - 3,368,690 (+)Ensembl
ChiLan1.0NW_0049554553,308,740 - 3,368,690 (+)NCBIChiLan1.0ChiLan1.0
KREMEN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22339,057,120 - 39,131,287 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12241,756,654 - 41,835,774 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02210,128,326 - 10,202,548 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12227,828,014 - 28,007,213 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2227,828,011 - 28,031,917 (+)EnsemblpanPan2panpan1.1
KREMEN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12622,408,397 - 22,481,646 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2622,407,506 - 22,480,384 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2622,280,486 - 22,353,730 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02622,783,070 - 22,856,290 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2622,782,815 - 22,851,716 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12622,492,122 - 22,565,437 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02622,756,210 - 22,829,458 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02622,819,719 - 22,893,111 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Kremen1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118112,667,995 - 112,715,143 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366573,155,958 - 3,202,658 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366573,155,564 - 3,206,385 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KREMEN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1446,254,326 - 46,323,354 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11446,254,248 - 46,323,355 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21449,218,268 - 49,287,935 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KREMEN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11911,943,787 - 12,056,706 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1911,943,835 - 12,014,759 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666045114,122,710 - 114,206,650 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kremen1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247475,377,996 - 5,445,504 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247475,377,996 - 5,449,203 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Kremen1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11174,164,607 - 74,227,098 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Kremen1
651 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:63
Count of miRNA genes:54
Interacting mature miRNAs:57
Transcripts:ENSRNOT00000013543
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631213Bw60Body weight QTL604.51retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)1484164970100078267Rat
1582236Gluco22Glucose level QTL 223.30.0164blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147764007196755654Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1459848686104848686Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1477914838104348525Rat
70153Bp59Blood pressure QTL 593.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)147297021087582095Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143067446985041098Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1433424686102238540Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1474255551109089856Rat
1582197Gluco27Glucose level QTL 273.40.0006blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)147764007196755654Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1462398852107398852Rat
1582250Gluco26Glucose level QTL 263.30.0009blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1477640071100078267Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1460854936105854936Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1474255551109089856Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1411334716100078267Rat
1582255Gluco29Glucose level QTL 293.10.0025blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)147764007196755654Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1459848686104848686Rat
1582209Gluco20Glucose level QTL 203.80.0005blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147764007196755654Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144261625899224555Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)146592028399224555Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)143941117087582095Rat

Markers in Region
D14Got71  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81484,353,866 - 84,354,170 (+)Marker Load Pipeline
Rnor_6.01485,496,178 - 85,496,475NCBIRnor6.0
Rnor_5.01486,168,411 - 86,168,708UniSTSRnor5.0
RGSC_v3.41485,902,091 - 85,902,388RGDRGSC3.4
RGSC_v3.41485,902,092 - 85,902,389UniSTSRGSC3.4
Celera1479,027,332 - 79,027,629UniSTS
RGSC_v3.11485,921,236 - 85,921,533RGD
RH 3.4 Map14566.7UniSTS
RH 3.4 Map14566.7RGD
RH 2.0 Map14703.4RGD
Cytogenetic Map14q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000083770   ⟹   ENSRNOP00000074509
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1480,084,403 - 80,127,920 (-)Ensembl
Rnor_6.0 Ensembl1485,438,707 - 85,484,275 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000110021   ⟹   ENSRNOP00000080592
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1484,297,700 - 84,361,614 (-)Ensembl
mRatBN7.2 Ensembl1480,084,403 - 80,147,516 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000120167   ⟹   ENSRNOP00000085129
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1484,298,464 - 84,341,867 (-)Ensembl
mRatBN7.2 Ensembl1480,084,403 - 80,127,821 (-)Ensembl
RefSeq Acc Id: NM_053649   ⟹   NP_446101
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81484,298,464 - 84,361,431 (-)NCBI
mRatBN7.21480,084,403 - 80,147,387 (-)NCBI
Rnor_6.01485,441,209 - 85,503,661 (-)NCBI
Rnor_5.01486,114,543 - 86,175,894 (-)NCBI
RGSC_v3.41485,845,443 - 85,909,575 (-)RGD
Celera1478,972,429 - 79,034,890 (-)RGD
Sequence:
RefSeq Acc Id: XM_039091556   ⟹   XP_038947484
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81484,295,931 - 84,361,534 (-)NCBI
mRatBN7.21480,081,870 - 80,147,489 (-)NCBI
RefSeq Acc Id: XM_063272802   ⟹   XP_063128872
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81484,295,931 - 84,307,365 (-)NCBI
RefSeq Acc Id: XM_063272803   ⟹   XP_063128873
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81484,295,931 - 84,307,364 (-)NCBI
RefSeq Acc Id: NP_446101   ⟸   NM_053649
- Peptide Label: precursor
- UniProtKB: Q924S4 (UniProtKB/Swiss-Prot),   A0A8I6G4R3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000074509   ⟸   ENSRNOT00000083770
RefSeq Acc Id: XP_038947484   ⟸   XM_039091556
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000080592   ⟸   ENSRNOT00000110021
Ensembl Acc Id: ENSRNOP00000085129   ⟸   ENSRNOT00000120167
RefSeq Acc Id: XP_063128872   ⟸   XM_063272802
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063128873   ⟸   XM_063272803
- Peptide Label: isoform X3
Protein Domains
CUB   Kringle   WSC

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q924S4-F1-model_v2 AlphaFold Q924S4 1-473 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620789 AgrOrtholog
BioCyc Gene G2FUF-15146 BioCyc
Ensembl Genes ENSRNOG00000051487 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000120167 ENTREZGENE
Gene3D-CATH 2.40.20.10 UniProtKB/Swiss-Prot
  2.60.120.290 UniProtKB/Swiss-Prot
InterPro CUB_dom UniProtKB/Swiss-Prot
  Kremen UniProtKB/Swiss-Prot
  Kremen_rcpt UniProtKB/Swiss-Prot
  Kringle UniProtKB/Swiss-Prot
  Kringle-like UniProtKB/Swiss-Prot
  Kringle_CS UniProtKB/Swiss-Prot
  Kringle_sf UniProtKB/Swiss-Prot
  Sperma_CUB_dom_sf UniProtKB/Swiss-Prot
  WSC_carb-bd UniProtKB/Swiss-Prot
KEGG Report rno:114107 UniProtKB/Swiss-Prot
NCBI Gene 114107 ENTREZGENE
PANTHER KREMEN PROTEIN UniProtKB/Swiss-Prot
  KREMEN PROTEIN 1 UniProtKB/Swiss-Prot
Pfam CUB UniProtKB/Swiss-Prot
  Kringle UniProtKB/Swiss-Prot
  WSC UniProtKB/Swiss-Prot
PhenoGen Kremen1 PhenoGen
PIRSF Kremen UniProtKB/Swiss-Prot
PRINTS KRINGLE UniProtKB/Swiss-Prot
PROSITE CUB UniProtKB/Swiss-Prot
  KRINGLE_1 UniProtKB/Swiss-Prot
  KRINGLE_2 UniProtKB/Swiss-Prot
  WSC UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000051487 RatGTEx
SMART CUB UniProtKB/Swiss-Prot
  SM00130 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF49854 UniProtKB/Swiss-Prot
  SSF57440 UniProtKB/Swiss-Prot
UniProt A0A8I6A3B6_RAT UniProtKB/TrEMBL
  A0A8I6G4R3 ENTREZGENE, UniProtKB/TrEMBL
  A6IKL4_RAT UniProtKB/TrEMBL
  A6IKL5_RAT UniProtKB/TrEMBL
  KREM1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Kremen1  kringle containing transmembrane protein 1  Kremen  kringle containing transmembrane protein  Symbol and Name updated 1299863 APPROVED
2004-12-14 Kremen  kringle containing transmembrane protein    kringle-coding gene marking the eye and the nose  Name updated 1299863 APPROVED
2002-08-07 Kremen  kringle-coding gene marking the eye and the nose      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_domains contains a kringle domain, a WSC domain, and CUB domains 633127
gene_protein 473 amino acid residues 633127