Bmp1 (bone morphogenetic protein 1) - Rat Genome Database

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Gene: Bmp1 (bone morphogenetic protein 1) Rattus norvegicus
Analyze
Symbol: Bmp1
Name: bone morphogenetic protein 1
RGD ID: 620739
Description: Predicted to enable identical protein binding activity and metalloendopeptidase activity. Predicted to be involved in dorsal/ventral pattern formation and protein processing. Predicted to act upstream of or within positive regulation of cartilage development. Located in extracellular space and vesicle. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 13. Orthologous to human BMP1 (bone morphogenetic protein 1); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: bone morphogenetic protein 1 (procollagen C-proteinase); procollagen C-proteinase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81551,961,310 - 52,005,597 (-)NCBIGRCr8
mRatBN7.21545,551,603 - 45,595,862 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1545,551,603 - 45,595,776 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1549,669,483 - 49,713,645 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01550,780,998 - 50,825,151 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01547,640,279 - 47,684,442 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01552,166,401 - 52,210,786 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1552,166,401 - 52,210,746 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01555,889,918 - 55,934,263 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41550,878,144 - 50,922,313 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11550,910,779 - 50,923,437 (-)NCBI
Celera1545,230,611 - 45,274,179 (-)NCBICelera
Cytogenetic Map15p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bmp1RatAcute Otitis Media  ISOBmp1 (Mus musculus)127284853mRNA:increased expression:middle ear (mouse)RGD 
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Object Symbol
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Term
Qualifier
Evidence
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Reference
Notes
Source
Original Reference(s)
Bmp1RatConotruncal Cardiac Defects  ISOBMP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Conotruncal heart malformationsClinVarPMID:28492532
Bmp1Ratgenetic disease  ISOBMP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:25741868 and PMID:28492532
Bmp1Ratidiopathic pulmonary fibrosis  ISOBMP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Fibrocystic pulmonary dysplasiaClinVarPMID:24033266 more ...
Bmp1Ratinterstitial lung disease 2  ISOBMP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Interstitial lung disease 2ClinVarPMID:24033266 more ...
Bmp1Ratosteogenesis imperfecta  ISOBMP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Osteogenesis Imperfecta and RecessiveClinVarPMID:24033266 and PMID:25741868
Bmp1Ratosteogenesis imperfecta  ISOBMP1 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:22482805 more ...
Bmp1Ratosteogenesis imperfecta  ISOBMP1 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:22482805 more ...
Bmp1Ratosteogenesis imperfecta type 13  ISOBMP1 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:15542026 more ...
Bmp1Ratosteogenesis imperfecta type 3  ISOBMP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Osteogenesis imperfecta type IIIClinVarPMID:25741868
Bmp1RatPulmonary Surfactant Metabolism Dysfunction 2  ISOBMP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Surfactant metabolism dysfunction more ...ClinVarPMID:24033266 more ...
Bmp1RatSurfactant Dysfunction  ISOBMP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Pulmonary surfactant metabolism dysfunctionClinVarPMID:24033266 more ...
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Object Symbol
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Source
Original Reference(s)
Bmp1Ratosteogenesis imperfecta type 13  ISOBMP1 (Homo sapiens)7240710 OMIM 

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Object Symbol
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Term
Qualifier
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Original Reference(s)
Bmp1Rat(1->4)-beta-D-glucan multiple interactionsISOBmp1 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of BMP1 mRNACTDPMID:36331819
Bmp1Rat1,1-dichloroethene increases expressionISOBmp1 (Mus musculus)6480464vinylidene chloride results in increased expression of BMP1 mRNACTDPMID:26682919
Bmp1Rat1,2-dimethylhydrazine increases expressionISOBmp1 (Mus musculus)64804641 and 2-Dimethylhydrazine results in increased expression of BMP1 mRNACTDPMID:22206623
Bmp1Rat17alpha-ethynylestradiol increases expressionISOBmp1 (Mus musculus)6480464Ethinyl Estradiol results in increased expression of BMP1 mRNACTDPMID:17942748
Bmp1Rat17alpha-ethynylestradiol multiple interactionsISOBmp1 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of BMP1 mRNACTDPMID:17942748
Bmp1Rat17beta-estradiol increases expressionISOBmp1 (Mus musculus)6480464Estradiol results in increased expression of BMP1 mRNACTDPMID:19484750 and PMID:39298647
Bmp1Rat17beta-estradiol multiple interactionsISOBMP1 (Homo sapiens)6480464[Estradiol co-treated with TGFB1 protein] results in increased expression of BMP1 mRNACTDPMID:30165855
Bmp1Rat2,2',4,4',5,5'-hexachlorobiphenyl affects expressionISOBMP1 (Homo sapiens)64804642 more ...CTDPMID:20638727
Bmp1Rat2,2',4,4'-Tetrabromodiphenyl ether increases expressionEXP 64804642 more ...CTDPMID:27291303
Bmp1Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOBmp1 (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of BMP1 mRNACTDPMID:17942748
Bmp1Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of BMP1 mRNACTDPMID:34747641
Bmp1Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOBmp1 (Mus musculus)6480464Tetrachlorodibenzodioxin results in decreased expression of BMP1 mRNACTDPMID:26290441
Bmp1Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOBmp1 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of BMP1 mRNACTDPMID:21570461
Bmp1Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOBmp1 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of BMP1 mRNACTDPMID:17942748
Bmp1Rat2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expressionISOBmp1 (Mus musculus)64804642 more ...CTDPMID:38648751
Bmp1Rat3,4-methylenedioxymethamphetamine increases expressionISOBmp1 (Mus musculus)6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of BMP1 mRNACTDPMID:20188158
Bmp1Rat4,4'-sulfonyldiphenol increases expressionISOBmp1 (Mus musculus)6480464bisphenol S results in increased expression of BMP1 mRNACTDPMID:39298647
Bmp1Rat4-(ethoxymethylene)-2-phenyloxazol-5-one increases expressionISOBmp1 (Mus musculus)6480464Oxazolone results in increased expression of BMP1 mRNACTDPMID:11379042
Bmp1Rat4-hydroxynon-2-enal decreases expressionISOBMP1 (Homo sapiens)64804644-hydroxy-2-nonenal results in decreased expression of BMP1 mRNACTDPMID:12419474
Bmp1Rat4-hydroxyphenyl retinamide decreases expressionISOBmp1 (Mus musculus)6480464Fenretinide results in decreased expression of BMP1 mRNACTDPMID:28973697

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Biological Process
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Object Symbol
Species
Term
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Reference
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Original Reference(s)
Bmp1Ratdorsal/ventral pattern formation involved_inIBAFB:FBgn0003719 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Bmp1Ratpositive regulation of cartilage development acts_upstream_of_or_withinISOBMP1 (Homo sapiens)1624291 PMID:3201241RGDPMID:3201241
Bmp1Ratpositive regulation of cartilage development acts_upstream_of_or_withinIEAUniProtKB:P13497 and ensembl:ENSP000003057141600115GO_REF:0000107EnsemblGO_REF:0000107
Bmp1Ratprotein processing involved_inIBAFB:FBgn0003719 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Bmp1Ratproteolysis involved_inISOBMP1 (Homo sapiens)1624291 PMID:16824737RGDPMID:16824737
Bmp1Ratproteolysis involved_inIEAUniProtKB-KW:KW-06451600115GO_REF:0000043UniProtGO_REF:0000043
Bmp1Ratproteolysis involved_inIEAInterPro:IPR001506 and InterPro:IPR0060261600115GO_REF:0000002InterProGO_REF:0000002
Bmp1Ratproteolysis involved_inIEAInterPro:IPR0015061600115GO_REF:0000002InterProGO_REF:0000002
Bmp1Ratproteolysis involved_inIEAUniProtKB:P13497 and ensembl:ENSP000003057141600115GO_REF:0000107EnsemblGO_REF:0000107
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Cellular Component

  
Object Symbol
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Reference
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Original Reference(s)
Bmp1Ratextracellular region located_inIEAUniProtKB-SubCell:SL-02431600115GO_REF:0000044UniProtGO_REF:0000044
Bmp1Ratextracellular region located_inIEAUniProtKB-KW:KW-09641600115GO_REF:0000043UniProtGO_REF:0000043
Bmp1Ratextracellular space is_active_inIBAFB:FBgn0003719 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Bmp1Ratextracellular space  IDA 2301841matrix vesicles - cell derived and extracellular vesicles that are initiation sites of mineralizationRGD 
Bmp1Ratvesicle  IDA 2301841matrix vesicles - cell derived and extracellular vesicles that are initiation sites of mineralizationRGD 

Molecular Function
1 to 20 of 22 rows

  
Object Symbol
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Term
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Reference
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Source
Original Reference(s)
Bmp1Ratcalcium ion binding enablesIEAInterPro:IPR001881 and InterPro:IPR0180971600115GO_REF:0000002InterProGO_REF:0000002
Bmp1Rathydrolase activity enablesIEAUniProtKB-KW:KW-03781600115GO_REF:0000043UniProtGO_REF:0000043
Bmp1Ratidentical protein binding enablesISOBMP1 (Homo sapiens)1624291UniProtKB:P13497 and PMID:19429706RGDPMID:19429706
Bmp1Ratidentical protein binding enablesIEAUniProtKB:P13497 and ensembl:ENSP000003057141600115GO_REF:0000107EnsemblGO_REF:0000107
Bmp1Ratmetal ion binding enablesIEAUniProtKB-KW:KW-04791600115GO_REF:0000043UniProtGO_REF:0000043
Bmp1Ratmetalloendopeptidase activity enablesIBAFB:FBgn0003719 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Bmp1Ratmetalloendopeptidase activity enablesIEAInterPro:IPR0015061600115GO_REF:0000002InterProGO_REF:0000002
Bmp1Ratmetalloendopeptidase activity enablesISOBmp1 (Mus musculus)1624291 PMID:19079247RGDPMID:19079247
Bmp1Ratmetalloendopeptidase activity enablesIEAUniRule:UR000120488 and UniRule:UR0009190201600115GO_REF:0000104UniProtGO_REF:0000104
Bmp1Ratmetalloendopeptidase activity enablesIEAUniProtKB:P98063 and ensembl:ENSMUSP000000226931600115GO_REF:0000107EnsemblGO_REF:0000107
Bmp1Ratmetalloendopeptidase activity enablesIEAInterPro:IPR001506 and InterPro:IPR0154461600115GO_REF:0000002InterProGO_REF:0000002
Bmp1Ratmetallopeptidase activity enablesIEAUniProtKB-KW:KW-04821600115GO_REF:0000043UniProtGO_REF:0000043
Bmp1Ratmetallopeptidase activity enablesIEAInterPro:IPR0240791600115GO_REF:0000002InterProGO_REF:0000002
Bmp1Ratmetallopeptidase activity enablesIEAInterPro:IPR006026 and InterPro:IPR0240791600115GO_REF:0000002InterProGO_REF:0000002
Bmp1Ratpeptidase activity enablesISOBMP1 (Homo sapiens)1624291 PMID:12393877 and PMID:16824737RGDPMID:12393877 and PMID:16824737
Bmp1Ratpeptidase activity enablesIEAUniProtKB-KW:KW-06451600115GO_REF:0000043UniProtGO_REF:0000043
Bmp1Ratpeptidase activity enablesIEAUniProtKB:P13497 and ensembl:ENSP000003057141600115GO_REF:0000107EnsemblGO_REF:0000107
Bmp1Ratprotein binding enablesISOBMP1 (Homo sapiens)1624291UniProtKB:O14793 more ...RGDPMID:19429706 more ...
Bmp1Ratprotein binding enablesISOBmp1 (Mus musculus)1624291PR:P97299 PMID:19079247RGDPMID:19079247
Bmp1Ratprotein binding enablesISOBMP1 (Homo sapiens) and UniProtKB:P13497-21624291UniProtKB:P07585 more ...RGDPMID:20026052 and PMID:21078975
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#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Matrix vesicles are carriers of bone morphogenetic proteins (BMPs), vascular endothelial growth factor (VEGF), and noncollagenous matrix proteins. Nahar NN, etal., J Bone Miner Metab. 2008;26(5):514-9. Epub 2008 Aug 30.
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Tissue remodeling in the acute otitis media mouse model. Sautter NB, etal., Int J Pediatr Otorhinolaryngol. 2011 Nov;75(11):1368-71. doi: 10.1016/j.ijporl.2011.07.026. Epub 2011 Sep 1.
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PMID:3201241   PMID:12393877   PMID:16824737   PMID:17071617   PMID:19079247   PMID:19429706   PMID:21415150   PMID:24006456   PMID:28684382  



Bmp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81551,961,310 - 52,005,597 (-)NCBIGRCr8
mRatBN7.21545,551,603 - 45,595,862 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1545,551,603 - 45,595,776 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1549,669,483 - 49,713,645 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01550,780,998 - 50,825,151 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01547,640,279 - 47,684,442 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01552,166,401 - 52,210,786 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1552,166,401 - 52,210,746 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01555,889,918 - 55,934,263 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41550,878,144 - 50,922,313 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11550,910,779 - 50,923,437 (-)NCBI
Celera1545,230,611 - 45,274,179 (-)NCBICelera
Cytogenetic Map15p11NCBI
BMP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38822,165,372 - 22,212,326 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl822,165,140 - 22,212,326 (+)EnsemblGRCh38hg38GRCh38
GRCh37822,022,885 - 22,069,839 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36822,078,835 - 22,125,782 (+)NCBINCBI36Build 36hg18NCBI36
Celera820,984,783 - 21,032,542 (+)NCBICelera
Cytogenetic Map8p21.3NCBI
HuRef820,564,967 - 20,612,031 (+)NCBIHuRef
CHM1_1822,224,312 - 22,271,500 (+)NCBICHM1_1
T2T-CHM13v2.0822,439,316 - 22,486,280 (+)NCBIT2T-CHM13v2.0
Bmp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391470,711,998 - 70,758,280 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1470,711,998 - 70,757,674 (-)EnsemblGRCm39 Ensembl
GRCm381470,474,555 - 70,520,716 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1470,474,558 - 70,520,234 (-)EnsemblGRCm38mm10GRCm38
MGSCv371470,874,362 - 70,920,067 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361469,209,638 - 69,255,268 (-)NCBIMGSCv36mm8
Celera1468,015,981 - 68,061,716 (-)NCBICelera
Cytogenetic Map14D2NCBI
cM Map1436.32NCBI
Bmp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540345,660,588 - 45,693,724 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540345,660,591 - 45,693,724 (+)NCBIChiLan1.0ChiLan1.0
BMP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2740,666,831 - 40,714,042 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1816,392,228 - 16,439,248 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0821,410,139 - 21,457,144 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1818,349,836 - 18,396,796 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl818,349,836 - 18,396,796 (+)Ensemblpanpan1.1panPan2
BMP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12535,043,594 - 35,087,282 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2535,020,751 - 35,087,545 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2535,633,298 - 35,676,927 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02535,255,039 - 35,298,679 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2535,255,044 - 35,298,662 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12535,200,533 - 35,244,157 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02535,055,062 - 35,098,676 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02535,210,570 - 35,254,197 (-)NCBIUU_Cfam_GSD_1.0
Bmp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494312,546,649 - 12,579,706 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365555,990,836 - 6,023,878 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365555,990,822 - 6,023,864 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BMP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl146,443,912 - 6,489,063 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1146,443,773 - 6,489,066 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2146,881,220 - 6,923,093 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BMP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1820,234,242 - 20,281,768 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl820,234,184 - 20,283,467 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605221,954,309 - 22,001,797 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bmp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475817,744,821 - 17,788,510 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475817,745,344 - 17,788,183 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Bmp1
105 total Variants

Predicted Target Of
Summary Value
Count of predictions:195
Count of miRNA genes:122
Interacting mature miRNAs:141
Transcripts:ENSRNOT00000046054
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


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The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1331729Rf42Renal function QTL 423.071kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)151736289773690657Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)152803066582262678Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
2293686Bmd36Bone mineral density QTL 367.40.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)153361105871477291Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151249614165205939Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15155302115Rat
2293691Bmd37Bone mineral density QTL 376.60.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)153361105871477291Rat
2293688Bss29Bone structure and strength QTL 295.310.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)151111114256111142Rat

1 to 10 of 27 rows
BI278614  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21545,551,817 - 45,551,986 (+)MAPPERmRatBN7.2
Rnor_6.01552,166,616 - 52,166,784NCBIRnor6.0
Rnor_5.01555,890,133 - 55,890,301UniSTSRnor5.0
RGSC_v3.41550,878,359 - 50,878,527UniSTSRGSC3.4
Celera1545,230,826 - 45,230,994UniSTS
Cytogenetic Map15p11UniSTS
RH94751  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81552,006,489 - 52,006,615 (+)Marker Load Pipeline
mRatBN7.21545,596,780 - 45,596,906 (+)MAPPERmRatBN7.2
Rnor_6.01552,211,751 - 52,211,876NCBIRnor6.0
Rnor_5.01555,935,268 - 55,935,393UniSTSRnor5.0
RGSC_v3.41550,923,318 - 50,923,443UniSTSRGSC3.4
Celera1545,275,184 - 45,275,309UniSTS
Cytogenetic Map15p11UniSTS
RH143871  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21545,556,132 - 45,556,291 (+)MAPPERmRatBN7.2
Rnor_6.01552,170,931 - 52,171,089NCBIRnor6.0
Rnor_5.01555,894,448 - 55,894,606UniSTSRnor5.0
RGSC_v3.41550,882,674 - 50,882,832UniSTSRGSC3.4
Celera1545,235,136 - 45,235,294UniSTS
Cytogenetic Map15p11UniSTS
RH136856  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21545,596,682 - 45,596,873 (+)MAPPERmRatBN7.2
Rnor_6.01552,211,653 - 52,211,843NCBIRnor6.0
Rnor_5.01555,935,170 - 55,935,360UniSTSRnor5.0
RGSC_v3.41550,923,220 - 50,923,410UniSTSRGSC3.4
Celera1545,275,086 - 45,275,276UniSTS
Cytogenetic Map15p11UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000046054   ⟹   ENSRNOP00000040287
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1545,551,603 - 45,595,776 (-)Ensembl
Rnor_6.0 Ensembl1552,166,401 - 52,210,746 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000099340   ⟹   ENSRNOP00000083692
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1545,583,813 - 45,595,776 (-)Ensembl
RefSeq Acc Id: NM_031323   ⟹   NP_112613
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81551,961,310 - 52,005,485 (-)NCBI
mRatBN7.21545,551,603 - 45,595,776 (-)NCBI
Rnor_6.01552,166,401 - 52,210,746 (-)NCBI
Rnor_5.01555,889,918 - 55,934,263 (-)NCBI
RGSC_v3.41550,878,144 - 50,922,313 (-)RGD
Celera1545,230,611 - 45,274,179 (-)RGD
Sequence:
RefSeq Acc Id: XM_006252285   ⟹   XP_006252347
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81551,961,312 - 51,994,213 (-)NCBI
mRatBN7.21545,551,605 - 45,584,510 (-)NCBI
Rnor_6.01552,166,403 - 52,199,169 (-)NCBI
Rnor_5.01555,889,918 - 55,934,263 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039093689   ⟹   XP_038949617
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81551,964,467 - 52,005,596 (-)NCBI
mRatBN7.21545,554,765 - 45,595,861 (-)NCBI
RefSeq Acc Id: XM_039093690   ⟹   XP_038949618
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81551,961,312 - 51,994,213 (-)NCBI
mRatBN7.21545,551,605 - 45,584,510 (-)NCBI
RefSeq Acc Id: XM_063274694   ⟹   XP_063130764
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81551,972,855 - 52,005,597 (-)NCBI
RefSeq Acc Id: XM_063274695   ⟹   XP_063130765
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81551,974,490 - 52,005,596 (-)NCBI
RefSeq Acc Id: NP_112613   ⟸   NM_031323
- Peptide Label: precursor
- UniProtKB: F1M798 (UniProtKB/TrEMBL),   A6HTK6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006252347   ⟸   XM_006252285
- Peptide Label: isoform X2
- UniProtKB: A6HTK7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000040287   ⟸   ENSRNOT00000046054
RefSeq Acc Id: XP_038949618   ⟸   XM_039093690
- Peptide Label: isoform X3
- UniProtKB: A6HTK7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038949617   ⟸   XM_039093689
- Peptide Label: isoform X1
CUB   EGF-like   Peptidase M12A

Name Modeler Protein Id AA Range Protein Structure
AF-F1M798-F1-model_v2 AlphaFold F1M798 1-990 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13699810
Promoter ID:EPDNEW_R10333
Type:initiation region
Name:Bmp1_1
Description:bone morphogenetic protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01552,210,683 - 52,210,743EPDNEW


1 to 40 of 53 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-13214 BioCyc
Ensembl Genes ENSRNOG00000010890 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000046054 ENTREZGENE
  ENSRNOT00000046054.5 UniProtKB/TrEMBL
  ENSRNOT00000099340.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.290 UniProtKB/TrEMBL
  3.40.390.10 UniProtKB/TrEMBL
  Laminin UniProtKB/TrEMBL
InterPro BMP_1/tolloid-like UniProtKB/TrEMBL
  CUB_dom UniProtKB/TrEMBL
  EG-like_dom UniProtKB/TrEMBL
  EGF-like_Ca-bd UniProtKB/TrEMBL
  EGF-type_Asp/Asn_hydroxyl_site UniProtKB/TrEMBL
  EGF_Ca-bd_CS UniProtKB/TrEMBL
  MetalloPept_cat_dom UniProtKB/TrEMBL
  NOTCH1_EGF-like UniProtKB/TrEMBL
  Peptidase_M12A UniProtKB/TrEMBL
  Peptidase_Metallo UniProtKB/TrEMBL
  sperma_CUB_dom UniProtKB/TrEMBL
  ZnMP_TLD/BMP1 UniProtKB/TrEMBL
KEGG Report rno:83470 UniProtKB/TrEMBL
NCBI Gene 83470 ENTREZGENE
PANTHER BONE MORPHOGENETIC PROTEIN 1 UniProtKB/TrEMBL
  BONE MORPHOGENETIC PROTEIN 1 UniProtKB/TrEMBL
  DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING UniProtKB/TrEMBL
  OVOCHYMASE-RELATED UniProtKB/TrEMBL
Pfam Astacin UniProtKB/TrEMBL
  CUB UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  FXa_inhibition UniProtKB/TrEMBL
PharmGKB BMP1 RGD
PhenoGen Bmp1 PhenoGen
PIRSF BMP_1/tolloid-like UniProtKB/TrEMBL
PRINTS ASTACIN UniProtKB/TrEMBL
PROSITE ASTACIN UniProtKB/TrEMBL
  ASX_HYDROXYL UniProtKB/TrEMBL
  CUB UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
1 to 40 of 53 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-11-17 Bmp1  bone morphogenetic protein 1    bone morphogenetic protein 1 (procollagen C-proetinase)  Name updated 1299863 APPROVED
2002-08-07 Bmp1  bone morphogenetic protein 1 (procollagen C-proetinase)      Symbol and Name status set to provisional 70820 PROVISIONAL

Note Type Note Reference
gene_product member of the TGF-beta superfamily 634636