Bmp1 (bone morphogenetic protein 1)

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Gene: Bmp1 (bone morphogenetic protein 1) Rattus norvegicus

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Symbol:

Bmp1

Name:

bone morphogenetic protein 1

RGD ID:

620739

Description:

Predicted to enable identical protein binding activity and metalloendopeptidase activity. Predicted to be involved in dorsal/ventral pattern formation and protein processing. Predicted to act upstream of or within positive regulation of cartilage development. Located in extracellular space and vesicle. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 13. Orthologous to human BMP1 (bone morphogenetic protein 1); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

bone morphogenetic protein 1 (procollagen C-proteinase); procollagen C-proteinase

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	BMP1 (bone morphogenetic protein 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Bmp1 (bone morphogenetic protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Bmp1 (bone morphogenetic protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	BMP1 (bone morphogenetic protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	BMP1 (bone morphogenetic protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Bmp1 (bone morphogenetic protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	BMP1 (bone morphogenetic protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	BMP1 (bone morphogenetic protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Bmp1 (bone morphogenetic protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Bmp1 (bone morphogenetic protein 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	BMP1 (bone morphogenetic protein 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	bmp1a (bone morphogenetic protein 1a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	bmp1b (bone morphogenetic protein 1b)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	nas-39	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	tld	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	tok	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	bmp1	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	51,961,310 - 52,005,597 (-)	NCBI		GRCr8
mRatBN7.2	15	45,551,603 - 45,595,862 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	45,551,603 - 45,595,776 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	15	49,669,483 - 49,713,645 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	50,780,998 - 50,825,151 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	47,640,279 - 47,684,442 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	52,166,401 - 52,210,786 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	52,166,401 - 52,210,746 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	15	55,889,918 - 55,934,263 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	15	50,878,144 - 50,922,313 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	15	50,910,779 - 50,923,437 (-)	NCBI
Celera	15	45,230,611 - 45,274,179 (-)	NCBI		Celera
Cytogenetic Map	15	p11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Acute Otitis Media (ISO)

Conotruncal Cardiac Defects (ISO)

genetic disease (ISO)

idiopathic pulmonary fibrosis (ISO)

interstitial lung disease 2 (ISO)

osteogenesis imperfecta (ISO)

osteogenesis imperfecta type 13 (ISO)

osteogenesis imperfecta type 3 (ISO)

Pulmonary Surfactant Metabolism Dysfunction 2 (ISO)

Surfactant Dysfunction (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,1-dichloroethene (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO)

3,4-methylenedioxymethamphetamine (ISO)

4-(ethoxymethylene)-2-phenyloxazol-5-one (ISO)

4-hydroxynon-2-enal (ISO)

4-hydroxyphenyl retinamide (ISO)

5-aza-2'-deoxycytidine (ISO)

6-propyl-2-thiouracil (EXP)

acrolein (ISO)

all-trans-retinoic acid (ISO)

alpha-pinene (ISO)

aluminium oxide (ISO)

ammonium chloride (EXP)

arsenite(3-) (ISO)

astemizole (EXP)

bacitracin (EXP)

benzo[a]pyrene (ISO)

beta-lapachone (ISO)

bis(2-chloroethyl) sulfide (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

butanal (ISO)

calciol (ISO)

carbon nanotube (ISO)

chlordecone (ISO)

chloroprene (EXP)

chromium(6+) (ISO)

cisplatin (EXP)

clofibric acid (EXP)

cobalt dichloride (ISO)

copper atom (ISO)

copper(0) (ISO)

corn oil (EXP)

cyclosporin A (ISO)

DDE (ISO)

decabromodiphenyl ether (EXP)

dextran sulfate (ISO)

dibenzo[a,l]pyrene (ISO)

dibutyl phthalate (ISO)

dimethylarsinic acid (ISO)

doxorubicin (ISO)

endosulfan (EXP)

fipronil (EXP)

flutamide (EXP)

gentamycin (EXP)

glycerol 2-phosphate (EXP)

graphene oxide (ISO)

L-ascorbic acid (EXP)

lead diacetate (ISO)

methotrexate (ISO)

N-nitrosodiethylamine (EXP)

nefazodone (EXP)

nickel atom (ISO)

nimesulide (EXP)

nitric oxide (ISO)

ozone (ISO)

paracetamol (ISO)

paraquat (EXP)

PCB138 (EXP)

perfluorooctane-1-sulfonic acid (ISO)

phenytoin (ISO)

pirinixic acid (ISO)

potassium chromate (ISO)

propiconazole (ISO)

quercetin (ISO)

rotenone (EXP)

S-butyl-DL-homocysteine (S,R)-sulfoximine (ISO)

simvastatin (EXP)

sodium arsenite (ISO)

Soman (EXP)

sunitinib (ISO)

tert-butyl hydroperoxide (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

triclosan (ISO)

tunicamycin (ISO)

valdecoxib (EXP)

valproic acid (ISO)

vancomycin (EXP)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

dorsal/ventral pattern formation (IBA)

positive regulation of cartilage development (ISO)

protein processing (IBA)

proteolysis (ISO)

Cellular Component

extracellular space (IBA,IDA)

vesicle (IDA)

Molecular Function

calcium ion binding (IEA)

identical protein binding (ISO)

metalloendopeptidase activity (IBA,ISO)

peptidase activity (ISO)

protein binding (ISO)

zinc ion binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	Matrix vesicles are carriers of bone morphogenetic proteins (BMPs), vascular endothelial growth factor (VEGF), and noncollagenous matrix proteins.	Nahar NN, etal., J Bone Miner Metab. 2008;26(5):514-9. Epub 2008 Aug 30.
5.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
6.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
7.	GOA pipeline	RGD automated data pipeline
8.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
10.	Tissue remodeling in the acute otitis media mouse model.	Sautter NB, etal., Int J Pediatr Otorhinolaryngol. 2011 Nov;75(11):1368-71. doi: 10.1016/j.ijporl.2011.07.026. Epub 2011 Sep 1.

Additional References at PubMed

PMID:3201241	PMID:12393877	PMID:16824737	PMID:17071617	PMID:19079247	PMID:19429706	PMID:21415150	PMID:24006456	PMID:28684382

Genomics

Comparative Map Data

Bmp1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	51,961,310 - 52,005,597 (-)	NCBI		GRCr8
mRatBN7.2	15	45,551,603 - 45,595,862 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	45,551,603 - 45,595,776 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	15	49,669,483 - 49,713,645 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	50,780,998 - 50,825,151 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	47,640,279 - 47,684,442 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	52,166,401 - 52,210,786 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	52,166,401 - 52,210,746 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	15	55,889,918 - 55,934,263 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	15	50,878,144 - 50,922,313 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	15	50,910,779 - 50,923,437 (-)	NCBI
Celera	15	45,230,611 - 45,274,179 (-)	NCBI		Celera
Cytogenetic Map	15	p11	NCBI

BMP1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	22,165,372 - 22,212,326 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	22,165,140 - 22,212,326 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	22,022,885 - 22,069,839 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	22,078,835 - 22,125,782 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	8	20,984,783 - 21,032,542 (+)	NCBI		Celera
Cytogenetic Map	8	p21.3	NCBI
HuRef	8	20,564,967 - 20,612,031 (+)	NCBI		HuRef
CHM1_1	8	22,224,312 - 22,271,500 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	8	22,439,316 - 22,486,280 (+)	NCBI		T2T-CHM13v2.0

Bmp1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	70,711,998 - 70,758,280 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	70,711,998 - 70,757,674 (-)	Ensembl		GRCm39 Ensembl
GRCm38	14	70,474,555 - 70,520,716 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	70,474,558 - 70,520,234 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	14	70,874,362 - 70,920,067 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	14	69,209,638 - 69,255,268 (-)	NCBI		MGSCv36	mm8
Celera	14	68,015,981 - 68,061,716 (-)	NCBI		Celera
Cytogenetic Map	14	D2	NCBI
cM Map	14	36.32	NCBI

Bmp1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955403	45,660,588 - 45,693,724 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955403	45,660,591 - 45,693,724 (+)	NCBI	ChiLan1.0	ChiLan1.0

BMP1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	40,666,831 - 40,714,042 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	16,392,228 - 16,439,248 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	21,410,139 - 21,457,144 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	18,349,836 - 18,396,796 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	18,349,836 - 18,396,796 (+)	Ensembl	panpan1.1		panPan2

BMP1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	25	35,043,594 - 35,087,282 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	25	35,020,751 - 35,087,545 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	25	35,633,298 - 35,676,927 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	25	35,255,039 - 35,298,679 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	25	35,255,044 - 35,298,662 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	25	35,200,533 - 35,244,157 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	25	35,055,062 - 35,098,676 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	25	35,210,570 - 35,254,197 (-)	NCBI		UU_Cfam_GSD_1.0

Bmp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404943	12,546,649 - 12,579,706 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936555	5,990,836 - 6,023,878 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936555	5,990,822 - 6,023,864 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

BMP1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	6,443,912 - 6,489,063 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	6,443,773 - 6,489,066 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	6,881,220 - 6,923,093 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

BMP1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	20,234,242 - 20,281,768 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	20,234,184 - 20,283,467 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666052	21,954,309 - 22,001,797 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Bmp1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624758	17,744,821 - 17,788,510 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624758	17,745,344 - 17,788,183 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Bmp1
105 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	195
Count of miRNA genes:	122
Interacting mature miRNAs:	141
Transcripts:	ENSRNOT00000046054
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331729	Rf42	Renal function QTL 42	3.071		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	15	17362897	73690657	Rat
1582227	Gluco30	Glucose level QTL 30	3.6	0.0003	blood glucose amount (VT:0000188)	absolute change in blood glucose level area under curve (CMO:0002034)	15	28030665	82262678	Rat
1582228	Epfw3	Epididymal fat weight QTL 3	4.1	0.0002	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	15	28030665	82262678	Rat
1578646	Bmd18	Bone mineral density QTL 18	5.2		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	15	22806240	98288169	Rat
1578647	Bmd17	Bone mineral density QTL 17	4		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	15	22806240	98288169	Rat
2293686	Bmd36	Bone mineral density QTL 36	7.4	0.0001	femur strength trait (VT:0010010)	femoral neck ultimate force (CMO:0001703)	15	33611058	71477291	Rat
2317750	Glom26	Glomerulus QTL 26	4.3		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	15	12496141	65205939	Rat
2298549	Neuinf12	Neuroinflammation QTL 12	3.5		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	15	1	55302115	Rat
2293691	Bmd37	Bone mineral density QTL 37	6.6	0.0001	femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	15	33611058	71477291	Rat
2293688	Bss29	Bone structure and strength QTL 29	5.31	0.0001	femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	15	11111142	56111142	Rat
1582214	Stl21	Serum triglyceride level QTL 21	3.1	0.022	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	15	28030665	82262678	Rat
631273	Lecl2	Lens clarity QTL 2		0.001	lens clarity trait (VT:0001304)	age of onset/diagnosis of cataract (CMO:0001584)	15	10596089	55596089	Rat
1300144	Rf23	Renal function QTL 23	3.61		renal blood flow trait (VT:2000006)	absolute change in renal vascular resistance (CMO:0001900)	15	40631268	98288169	Rat
2300167	Bmd63	Bone mineral density QTL 63	5.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	15	11111142	56111142	Rat
738017	Hcas7	Hepatocarcinoma susceptibility QTL 7	2.91		liver integrity trait (VT:0010547)	liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)	15	2266368	46921453	Rat
152025253	Hrtrt24	Heart rate QTL 24	3.82		heart pumping trait (VT:2000009)		15	27885774	86257085	Rat
10054130	Srcrt8	Stress Responsive Cort QTL 8	2.18	0.0085	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	15	22117933	67117933	Rat
2300173	Bmd62	Bone mineral density QTL 62	12.8	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	15	11111142	56111142	Rat
2324620	Coatc3	Coat color QTL 3			coat/hair pigmentation trait (VT:0010463)	pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)	15	19856566	46187442	Rat
61424	Scl1	Serum cholesterol level QTL 1	7.7	0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	15	16725528	80672115	Rat
1582251	Gluco24	Glucose level QTL 24	3.2	0.0008	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	15	5530756	50530756	Rat
1598828	Glom14	Glomerulus QTL 14	2.5		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	15	34054139	79054139	Rat
1582242	Gluco28	Glucose level QTL 28	3.3	0.0008	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	15	28030665	82262678	Rat
2306968	Anxrr23	Anxiety related response QTL 23	4.83		reflex trait (VT:0001961)	amplitude of the acoustic startle response (CMO:0001520)	15	40631268	46187442	Rat
1578660	Bss19	Bone structure and strength QTL 19	4.3		femur morphology trait (VT:0000559)	bone trabecular cross-sectional area (CMO:0002311)	15	22806240	98288169	Rat
1582244	Bw79	Body weight QTL 79	4	0.0002	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	15	28030665	82262678	Rat
7411725	Strs7	Sensitivity to stroke QTL 7	3.8		cerebrum integrity trait (VT:0010549)	percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)	15	40289901	49308583	Rat

Markers in Region

BI278614

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	45,551,817 - 45,551,986 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	52,166,616 - 52,166,784	NCBI	Rnor6.0
Rnor_5.0	15	55,890,133 - 55,890,301	UniSTS	Rnor5.0
RGSC_v3.4	15	50,878,359 - 50,878,527	UniSTS	RGSC3.4
Celera	15	45,230,826 - 45,230,994	UniSTS
Cytogenetic Map	15	p11	UniSTS

RH94751

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	45,596,780 - 45,596,906 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	52,211,751 - 52,211,876	NCBI	Rnor6.0
Rnor_5.0	15	55,935,268 - 55,935,393	UniSTS	Rnor5.0
RGSC_v3.4	15	50,923,318 - 50,923,443	UniSTS	RGSC3.4
Celera	15	45,275,184 - 45,275,309	UniSTS
Cytogenetic Map	15	p11	UniSTS

RH143871

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	45,556,132 - 45,556,291 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	52,170,931 - 52,171,089	NCBI	Rnor6.0
Rnor_5.0	15	55,894,448 - 55,894,606	UniSTS	Rnor5.0
RGSC_v3.4	15	50,882,674 - 50,882,832	UniSTS	RGSC3.4
Celera	15	45,235,136 - 45,235,294	UniSTS
Cytogenetic Map	15	p11	UniSTS

RH136856

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	45,596,682 - 45,596,873 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	52,211,653 - 52,211,843	NCBI	Rnor6.0
Rnor_5.0	15	55,935,170 - 55,935,360	UniSTS	Rnor5.0
RGSC_v3.4	15	50,923,220 - 50,923,410	UniSTS	RGSC3.4
Celera	15	45,275,086 - 45,275,276	UniSTS
Cytogenetic Map	15	p11	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_031323	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006252285	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008770834	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039093689	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039093690	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063274694	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063274695	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB012139	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB073100	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473951	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ220891	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000046054 ⟹ ENSRNOP00000040287

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	15	45,551,603 - 45,595,776 (-)	Ensembl
Rnor_6.0 Ensembl	15	52,166,401 - 52,210,746 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000099340 ⟹ ENSRNOP00000083692

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	15	45,583,813 - 45,595,776 (-)	Ensembl

RefSeq Acc Id:

NM_031323 ⟹ NP_112613

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	51,961,310 - 52,005,485 (-)	NCBI
mRatBN7.2	15	45,551,603 - 45,595,776 (-)	NCBI
Rnor_6.0	15	52,166,401 - 52,210,746 (-)	NCBI
Rnor_5.0	15	55,889,918 - 55,934,263 (-)	NCBI
RGSC_v3.4	15	50,878,144 - 50,922,313 (-)	RGD
Celera	15	45,230,611 - 45,274,179 (-)	RGD

Sequence:

show sequence

GGAAACGGGACGGGAAGAGGTGGCCTCGGGGGGAGAGCGCCTCCCCTTCGCCTTCAGCGCTCCC
TTCCCGGTCGCCCCGCTCCCGCGTCCGGGCGCGACCGCCACCGCTGCCCGCCAGCATGCCCGGC
GTGGCCCGCCCGCCGCTGCCGCTGCTGTCGCTGCCACTGCTGCTACTGCTGCTGCTCCCGCGCG
CCGGCCGGCCGCTGGACTTGGCCGACTACACCTACGACCTGGGCGAGGAGGACGCCCCGGAGCT
CCTCAACTACAAAGACCCCTGCAAGGCGGCTGCCTTTCTTGGGGACATTGCCCTGGATGAGGAG
GACTTGAGGGCCTTCCGGGTGCAGCAGGCTGCAGTTCTCAGACAACAAACAGCCCAGAGGTCGT
CCATCAAAGCTGCAGGGAACTCTTCTGCCCTGGGTAGACAGAGCACGAGTGGGCAGCCGCAGAG
GGGAAGCAGAGGCAGATGGAGAAGCAGGCCTCGGAGCAGGCGGGCAGCGACATCCAGACCAGAG
CGAGTGTGGCCCGATGGGGTCATCCCATTTGTCATCGGAGGGAATTTCACTGGCAGCCAGAGGG
CAGTCTTCCGGCAGGCCATGAGACACTGGGAGAAGCATACCTGTGTCACCTTCTTGGAGCGCAC
AGATGAGGACAGCTATATTGTATTCACCTACCGACCCTGCGGGTGCTGCTCCTACGTGGGTCGC
CGAGGTGGGGGCCCCCAGGCCATCTCCATCGGCAAGAACTGTGACAAGTTTGGCATCGTGGTCC
ATGAGCTGGGCCATGTCATTGGCTTCTGGCACGAGCACACGCGGCCCGACCGGGACCGCCATGT
CTCTATTGTACGGGAGAACATACAGCCAGGGCAGGAGTATAACTTCTTGAAGATGGAAGTTCAG
GAAGTCGAGTCCTTGGGAGAGACCTATGACTTTGACAGTATCATGCACTATGCCCGGAACACGT
TCTCCAGGGGCATCTTCCTGGACACCATTGTTCCCAAGTATGAGGTGAATGGGGTGAAGCCTTC
CATTGGCCAAAGGACCCGACTCAGCAAGGGGGACATCGCTCAGGCCCGGAAGCTCTACAAATGC
CCAGCCTGTGGTGAGACCCTCCAAGACAGCACTGGCAACTTCTCCTCCCCTGAGTATCCCAATG
GCTACTCTGCCCACATGCACTGTGTATGGCGTATCTCTGTCACACCGGGGGAGAAGATTATTCT
GAACTTCACATCTATGGACCTGTACCGTAGCCGCCTGTGCTGGTATGACTATGTGGAGGTGCGG
GATGGCTTCTGGAGAAAGGCGCCCCTCCGAGGCCGGTTCTGTGGGGGGAAACTCCCCGAGCCCA
TTGTCTCCACCGACAGCCGCCTCTGGGTGGAATTCCGAAGCAGCAGCAATTGGGTTGGAAAGGG
CTTCTTTGCTGTCTACGAAGCCATTTGCGGTGGTGACGTGAAAAAGGATAACGGTCACATCCAG
TCACCCAATTACCCCGACGATTACCGGCCCAGCAAAGTCTGCATCTGGCGGATCCAGGTGTCTG
AGGGTTTCCACGTGGGCCTCACGTTCCAGTCCTTTGAGATCGAGCGTCACGACAGTTGTGCCTA
CGACTACCTGGAGGTCCGAGATGGGCACAGTGAGAGCAGCAACCTCATTGGGCGATATTGTGGG
TATGAGAAGCCTGATGACATCAAAAGCACATCTAGTCGGCTCTGGCTCAAGTTCGTCTCCGATG
GGTCCATTAACAAAGCTGGCTTTGCAGTCAACTTTTTCAAAGAGGTAGATGAGTGTTCAAGGCC
CAACCGCGGGGGCTGTGAGCAGCGGTGCCTAAACACCCTGGGCAGCTACAAGTGCAGCTGTGAC
CCCGGCTATGAGCTGGCCCCAGACAAGCGTCGGTGTGAAGCTGCCTGCGGTGGATTCCTCACCA
AGCTCAATGGCTCCATCACCAGCCCCGGTTGGCCCAAAGAGTACCCTCCCAACAAAAACTGCAT
CTGGCAGTTGGTGGCCCCCACCCAGTACCGTATCTCCCTGCAATTTGACTTCTTCGAGACTGAG
GGCAATGATGTGTGCAAGTATGATTTCGTGGAGGTGCGCAGCGGACTCACAGCCGACTCTAAAC
TACATGGCAAGTTCTGTGGCTCCGAGAAACCAGAGGTCATCACTTCCCAGTACAACAACATGCG
TGTGGAGTTCAAGTCTGACAATACTGTGTCCAAAAAGGGCTTCAAGGCCCACTTCTTCTCAGAC
AAGGATGAATGTTCCAAGGACAATGGTGGCTGCCAGCAAGACTGCGTGAACACATTTGGCAGCT
ACGAGTGTCAGTGTCGCAGCGGCTTTGTCCTTCACGACAACAAACATGACTGTAAGGAAGCCGG
CTGTGAGCACAAAGTGACATCCACCAGTGGCACCATCACCAGCCCCAACTGGCCTGACAAGTAC
CCCAGCAAGAAGGAGTGTACGTGGGCTATCTCCAGCACCCCTGGGCACCGGGTGAAGCTGACTT
TTGTGGAGATGGATATTGAGTCTCAGCCTGAATGCGCTTATGACCACCTGGAGGTGTTTGATGG
GCGTGATGCCAAGGCGCCAGTCCTTGGCCGATTCTGTGGCAGTAAGAAGCCTGAGCCAGTCCTG
GCTACCGGCAACCGCATGTTCTTGCGCTTCTACTCAGACAACTCAGTACAGAGGAAAGGTTTCC
AGGCCTCCCACTCCACAGAGTGTGGGGGCCAAGTGCGGGCAGATGTGAAGACCAAAGACCTTTA
TTCCCATGCCCAGTTTGGTGATAACAACTACCCCGGAGGGGTGGACTGCGAGTGGGTGATTGTG
GCAGAGGAAGGCTATGGCGTGGAGTTGGTGTTCCAGACCTTCGAGGTAGAGGAGGAGACCGACT
GTGGCTATGACTACATGGAGCTCTTCGACGGCTACGACAGCACAGCTCCTAGACTGGGGCGCTA
CTGTGGCTCTGGGCCTCCTGAGGAAGTGTACTCGGCCGGAGACTCTGTCCTGGTGAAGTTCCAC
TCTGATGACACCATCTCCAAGAAAGGCTTTCACCTGCGGTACACAAGCACCAAGTTCCAGGACA
CACTCCACAGCAGGAAGTGACCATGGCTCCCGCTCAGTAGTGGGAACTGGAGTCCTGCTTCCCT
AGATCACCCAGACTGGACAACGGGGGACGGGGGGTGACAGGCAGATGGTGATGCATTGTCCCTC
ACCCCCAGGCACCAGGACCTACTGGGCCAGTGGGCCAGGCGTCGTCAGGAGGTAGGAGACTTGG
ACTCCTTAAGCCAGTCTCCCACTGCCTCCTGTCAGTGGGCCAGGGAACCAGAGCTTCCACCAAG
ACACTTGAAGTGACCATTCCTCCTTGGGGCCCTGCCTGGGGTAAGACAGTCTCTATGCAGGACC
CTGCGGCCTTCCCTACACGCTGTATTGTGTAGAGCCGGTGGCCCTAATCTTCATTGTAATGTAC
ATTTCCTGCCCCTTCTCCAGCCTTGATTTGATTTTATTTTGACCCACCGCTTCCATGCTTTCTG
GGTACCCCTCAGAGCTGTGGTGGGGAGTTGGAGAAGAGGGAGTGGATAAGTAAGACAGGGCTTC
TCTTAGGCTCACTGGCCACACCAGGGCACCCCAACCAATAAACAGAAAGTGTTACAGCCAATA

hide sequence

RefSeq Acc Id:

XM_006252285 ⟹ XP_006252347

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	51,961,312 - 51,994,213 (-)	NCBI
mRatBN7.2	15	45,551,605 - 45,584,510 (-)	NCBI
Rnor_6.0	15	52,166,403 - 52,199,169 (-)	NCBI
Rnor_5.0	15	55,889,918 - 55,934,263 (-)	NCBI

Sequence:

show sequence

GCAGCCAGAGGGCAGTCTTCCGGCAGGCCATGAGACACTGGGAGAAGCATACCTGTGTCACCTT
CTTGGAGCGCACAGATGAGGACAGCTATATTGTATTCACCTACCGACCCTGCGGCTCGGGACCA
CCCCCCTGAGCTGGCCCCGCCCTCCAGGTGCTGCTCCTACGTGGGTCGCCGAGGTGGGGGCCCC
CAGGCCATCTCCATCGGCAAGAACTGTGACAAGTTTGGCATCGTGGTCCATGAGCTGGGCCATG
TCATTGGCTTCTGGCACGAGCACACGCGGCCCGACCGGGACCGCCATGTCTCTATTGTACGGGA
GAACATACAGCCAGGGCAGGAGTATAACTTCTTGAAGATGGAAGTTCAGGAAGTCGAGTCCTTG
GGAGAGACCTATGACTTTGACAGTATCATGCACTATGCCCGGAACACGTTCTCCAGGGGCATCT
TCCTGGACACCATTGTTCCCAAGTATGAGGTGAATGGGGTGAAGCCTTCCATTGGCCAAAGGAC
CCGACTCAGCAAGGGGGACATCGCTCAGGCCCGGAAGCTCTACAAATGCCCAGCCTGTGGTGAG
ACCCTCCAAGACAGCACTGGCAACTTCTCCTCCCCTGAGTATCCCAATGGCTACTCTGCCCACA
TGCACTGTGTATGGCGTATCTCTGTCACACCGGGGGAGAAGATTATTCTGAACTTCACATCTAT
GGACCTGTACCGTAGCCGCCTGTGCTGGTATGACTATGTGGAGGTGCGGGATGGCTTCTGGAGA
AAGGCGCCCCTCCGAGGCCGGTTCTGTGGGGGGAAACTCCCCGAGCCCATTGTCTCCACCGACA
GCCGCCTCTGGGTGGAATTCCGAAGCAGCAGCAATTGGGTTGGAAAGGGCTTCTTTGCTGTCTA
CGAAGCCATTTGCGGTGGTGACGTGAAAAAGGATAACGGTCACATCCAGTCACCCAATTACCCC
GACGATTACCGGCCCAGCAAAGTCTGCATCTGGCGGATCCAGGTGTCTGAGGGTTTCCACGTGG
GCCTCACGTTCCAGTCCTTTGAGATCGAGCGTCACGACAGTTGTGCCTACGACTACCTGGAGGT
CCGAGATGGGCACAGTGAGAGCAGCAACCTCATTGGGCGATATTGTGGGTATGAGAAGCCTGAT
GACATCAAAAGCACATCTAGTCGGCTCTGGCTCAAGTTCGTCTCCGATGGGTCCATTAACAAAG
CTGGCTTTGCAGTCAACTTTTTCAAAGAGGTAGATGAGTGTTCAAGGCCCAACCGCGGGGGCTG
TGAGCAGCGGTGCCTAAACACCCTGGGCAGCTACAAGTGCAGCTGTGACCCCGGCTATGAGCTG
GCCCCAGACAAGCGTCGGTGTGAAGCTGCCTGCGGTGGATTCCTCACCAAGCTCAATGGCTCCA
TCACCAGCCCCGGTTGGCCCAAAGAGTACCCTCCCAACAAAAACTGCATCTGGCAGTTGGTGGC
CCCCACCCAGTACCGTATCTCCCTGCAATTTGACTTCTTCGAGACTGAGGGCAATGATGTGTGC
AAGTATGATTTCGTGGAGGTGCGCAGCGGACTCACAGCCGACTCTAAACTACATGGCAAGTTCT
GTGGCTCCGAGAAACCAGAGGTCATCACTTCCCAGTACAACAACATGCGTGTGGAGTTCAAGTC
TGACAATACTGTGTCCAAAAAGGGCTTCAAGGCCCACTTCTTCTCAGACAAGGATGAATGTTCC
AAGGACAATGGTGGCTGCCAGCAAGACTGCGTGAACACATTTGGCAGCTACGAGTGTCAGTGTC
GCAGCGGCTTTGTCCTTCACGACAACAAACATGACTGTAAGGAAGCCGGCTGTGAGCACAAAGT
GACATCCACCAGTGGCACCATCACCAGCCCCAACTGGCCTGACAAGTACCCCAGCAAGAAGGAG
TGTACGTGGGCTATCTCCAGCACCCCTGGGCACCGGGTGAAGCTGACTTTTGTGGAGATGGATA
TTGAGTCTCAGCCTGAATGCGCTTATGACCACCTGGAGGTGTTTGATGGGCGTGATGCCAAGGC
GCCAGTCCTTGGCCGATTCTGTGGCAGTAAGAAGCCTGAGCCAGTCCTGGCTACCGGCAACCGC
ATGTTCTTGCGCTTCTACTCAGACAACTCAGTACAGAGGAAAGGTTTCCAGGCCTCCCACTCCA
CAGAGTGTGGGGGCCAAGTGCGGGCAGATGTGAAGACCAAAGACCTTTATTCCCATGCCCAGTT
TGGTGATAACAACTACCCCGGAGGGGTGGACTGCGAGTGGGTGATTGTGGCAGAGGAAGGCTAT
GGCGTGGAGTTGGTGTTCCAGACCTTCGAGGTAGAGGAGGAGACCGACTGTGGCTATGACTACA
TGGAGCTCTTCGACGGCTACGACAGCACAGCTCCTAGACTGGGGCGCTACTGTGGCTCTGGGCC
TCCTGAGGAAGTGTACTCGGCCGGAGACTCTGTCCTGGTGAAGTTCCACTCTGATGACACCATC
TCCAAGAAAGGCTTTCACCTGCGGTACACAAGCACCAAGTTCCAGGACACACTCCACAGCAGGA
AGTGACCATGGCTCCCGCTCAGTAGTGGGAACTGGAGTCCTGCTTCCCTAGATCACCCAGACTG
GACAACGGGGGACGGGGGGTGACAGGCAGATGGTGATGCATTGTCCCTCACCCCCAGGCACCAG
GACCTACTGGGCCAGTGGGCCAGGCGTCGTCAGGAGGTAGGAGACTTGGACTCCTTAAGCCAGT
CTCCCACTGCCTCCTGTCAGTGGGCCAGGGAACCAGAGCTTCCACCAAGACACTTGAAGTGACC
ATTCCTCCTTGGGGCCCTGCCTGGGGTAAGACAGTCTCTATGCAGGACCCTGCGGCCTTCCCTA
CACGCTGTATTGTGTAGAGCCGGTGGCCCTAATCTTCATTGTAATGTACATTTCCTGCCCCTTC
TCCAGCCTTGATTTGATTTTATTTTGACCCACCGCTTCCATGCTTTCTGGGTACCCCTCAGAGC
TGTGGTGGGGAGTTGGAGAAGAGGGAGTGGATAAGTAAGACAGGGCTTCTCTTAGGCTCACTGG
CCACACCAGGGCACCCCAACCAATAAACAGAAAGTGTTACAGCCAA

hide sequence

RefSeq Acc Id:

XM_039093689 ⟹ XP_038949617

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	51,964,467 - 52,005,596 (-)	NCBI
mRatBN7.2	15	45,554,765 - 45,595,861 (-)	NCBI

RefSeq Acc Id:

XM_039093690 ⟹ XP_038949618

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	51,961,312 - 51,994,213 (-)	NCBI
mRatBN7.2	15	45,551,605 - 45,584,510 (-)	NCBI

RefSeq Acc Id:

XM_063274694 ⟹ XP_063130764

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	51,972,855 - 52,005,597 (-)	NCBI

RefSeq Acc Id:

XM_063274695 ⟹ XP_063130765

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	51,974,490 - 52,005,596 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_112613	(Get FASTA)	NCBI Sequence Viewer
	XP_006252347	(Get FASTA)	NCBI Sequence Viewer
	XP_038949617	(Get FASTA)	NCBI Sequence Viewer
	XP_038949618	(Get FASTA)	NCBI Sequence Viewer
	XP_063130764	(Get FASTA)	NCBI Sequence Viewer
	XP_063130765	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	BAA75639	(Get FASTA)	NCBI Sequence Viewer
	BAB69961	(Get FASTA)	NCBI Sequence Viewer
	EDM02219	(Get FASTA)	NCBI Sequence Viewer
	EDM02220	(Get FASTA)	NCBI Sequence Viewer
	EDM02221	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000040287.4
	ENSRNOP00000083692.1

RefSeq Acc Id:	NP_112613 ⟸ NM_031323
- Peptide Label:	precursor
- UniProtKB:	F1M798 (UniProtKB/TrEMBL), A6HTK6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPGVARPPLPLLSLPLLLLLLLPRAGRPLDLADYTYDLGEEDAPELLNYKDPCKAAAFLGDIAL DEEDLRAFRVQQAAVLRQQTAQRSSIKAAGNSSALGRQSTSGQPQRGSRGRWRSRPRSRRAATS RPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSY VGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKM EVQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPSIGQRTRLSKGDIAQARKL YKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSMDLYRSRLCWYDYV EVRDGFWRKAPLRGRFCGGKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKKDNG HIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSNLIGR YCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKC SCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFF ETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF FSDKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCEHKVTSTSGTITSPNWP DKYPSKKECTWAISSTPGHRVKLTFVEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPE PVLATGNRMFLRFYSDNSVQRKGFQASHSTECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEW VIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLV KFHSDDTISKKGFHLRYTSTKFQDTLHSRK hide sequence

RefSeq Acc Id:	XP_006252347 ⟸ XM_006252285
- Peptide Label:	isoform X2
- UniProtKB:	A6HTK7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MRTAILYSPTDPAARDHPPELAPPSRCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFW HEHTRPDRDRHVSIVRENIQPGQEYNFLKMEVQEVESLGETYDFDSIMHYARNTFSRGIFLDTI VPKYEVNGVKPSIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVW RISVTPGEKIILNFTSMDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGGKLPEPIVSTDSRLWV EFRSSSNWVGKGFFAVYEAICGGDVKKDNGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQ SFEIERHDSCAYDYLEVRDGHSESSNLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAV NFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPG WPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEK PEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVNTFGSYECQCRSGFV LHDNKHDCKEAGCEHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFVEMDIESQP ECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGNRMFLRFYSDNSVQRKGFQASHSTECGG QVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFD GYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTISKKGFHLRYTSTKFQDTLHSRK hide sequence

Ensembl Acc Id:

ENSRNOP00000040287 ⟸ ENSRNOT00000046054

RefSeq Acc Id:	XP_038949618 ⟸ XM_039093690
- Peptide Label:	isoform X3
- UniProtKB:	A6HTK7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038949617 ⟸ XM_039093689
- Peptide Label:	isoform X1

Ensembl Acc Id:

ENSRNOP00000083692 ⟸ ENSRNOT00000099340

RefSeq Acc Id:	XP_063130764 ⟸ XM_063274694
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_063130765 ⟸ XM_063274695
- Peptide Label:	isoform X5

Protein Domains

CUB EGF-like Peptidase M12A

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1M798-F1-model_v2	AlphaFold	F1M798	1-990	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13699810

Promoter ID:

EPDNEW_R10333

Type:

initiation region

Name:

Bmp1_1

Description:

bone morphogenetic protein 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	15	52,210,683 - 52,210,743	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620739	AgrOrtholog
BioCyc Gene	G2FUF-13214	BioCyc
Ensembl Genes	ENSRNOG00000010890	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000046054.5	UniProtKB/TrEMBL
	ENSRNOT00000099340.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.120.290	UniProtKB/TrEMBL
	3.40.390.10	UniProtKB/TrEMBL
	Laminin	UniProtKB/TrEMBL
InterPro	BMP_1/tolloid-like	UniProtKB/TrEMBL
	CUB_dom	UniProtKB/TrEMBL
	Dev_metalloprotease_endo_rcpt	UniProtKB/TrEMBL
	EG-like_dom	UniProtKB/TrEMBL
	EGF-like_Ca-bd	UniProtKB/TrEMBL
	EGF-type_Asp/Asn_hydroxyl_site	UniProtKB/TrEMBL
	EGF_Ca-bd_CS	UniProtKB/TrEMBL
	MetalloPept_cat_dom	UniProtKB/TrEMBL
	NOTCH1_EGF-like	UniProtKB/TrEMBL
	Peptidase_M12A	UniProtKB/TrEMBL
	Peptidase_Metallo	UniProtKB/TrEMBL
	sperma_CUB_dom	UniProtKB/TrEMBL
	ZnMP_TLD/BMP1	UniProtKB/TrEMBL
KEGG Report	rno:83470	UniProtKB/TrEMBL
NCBI Gene	83470	ENTREZGENE
PANTHER	BONE MORPHOGENETIC PROTEIN 1	UniProtKB/TrEMBL
	BONE MORPHOGENETIC PROTEIN 1	UniProtKB/TrEMBL
	DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING	UniProtKB/TrEMBL
	OVOCHYMASE-RELATED	UniProtKB/TrEMBL
Pfam	Astacin	UniProtKB/TrEMBL
	CUB	UniProtKB/TrEMBL
	EGF_CA	UniProtKB/TrEMBL
	FXa_inhibition	UniProtKB/TrEMBL
PharmGKB	BMP1	RGD
PhenoGen	Bmp1	PhenoGen
PIRSF	BMP_1/tolloid-like	UniProtKB/TrEMBL
PRINTS	ASTACIN	UniProtKB/TrEMBL
PROSITE	ASTACIN	UniProtKB/TrEMBL
	ASX_HYDROXYL	UniProtKB/TrEMBL
	CUB	UniProtKB/TrEMBL
	EGF_2	UniProtKB/TrEMBL
	EGF_3	UniProtKB/TrEMBL
	EGF_CA	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000010890	RatGTEx
SMART	CUB	UniProtKB/TrEMBL
	EGF	UniProtKB/TrEMBL
	EGF_CA	UniProtKB/TrEMBL
	ZnMc	UniProtKB/TrEMBL
Superfamily-SCOP	CUB	UniProtKB/TrEMBL
	EGF/Laminin	UniProtKB/TrEMBL
	Metalloproteases ('zincins'), catalytic domain	UniProtKB/TrEMBL
UniProt	A0A8I6A0H3_RAT	UniProtKB/TrEMBL
	A6HTK6	ENTREZGENE, UniProtKB/TrEMBL
	A6HTK7	ENTREZGENE, UniProtKB/TrEMBL
	A6HTK8_RAT	UniProtKB/TrEMBL
	F1M798	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-11-17	Bmp1	bone morphogenetic protein 1		bone morphogenetic protein 1 (procollagen C-proetinase)	Name updated	1299863	APPROVED
2002-08-07	Bmp1	bone morphogenetic protein 1 (procollagen C-proetinase)			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_product	member of the TGF-beta superfamily	634636

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM