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Gene: Abtb2 (ankyrin repeat and BTB domain containing 2) Rattus norvegicus

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Symbol:

Abtb2

Name:

ankyrin repeat and BTB domain containing 2

RGD ID:

620724

Description:

Predicted to enable protein heterodimerization activity. Predicted to act upstream of or within cellular response to toxic substance. Orthologous to human ABTB2 (ankyrin repeat and BTB domain containing 2); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

ankyrin repeat and BTB (POZ) domain containing 2; ankyrin repeat and BTB/POZ domain-containing protein 2; Cca3; confluent 3Y1 cell-associated protein

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	110,409,672 - 110,563,488 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	110,409,627 - 110,563,487 (+)	Ensembl				GRCr8
mRatBN7.2	3	89,954,726 - 90,108,549 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	89,954,713 - 90,108,548 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	93,448,249 - 93,601,949 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	102,047,320 - 102,201,032 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	99,878,295 - 100,032,334 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	93,494,706 - 93,648,750 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	93,495,106 - 93,647,721 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	100,136,224 - 100,290,000 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	88,858,336 - 89,012,166 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	89,022,954 - 89,176,876 (+)	NCBI		Celera
RGSC_v3.1	3	88,754,763 - 88,908,594 (+)	NCBI
Cytogenetic Map	3	q32	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-demecolcine (ISO)

(1->4)-beta-D-glucan (ISO)

1-naphthyl isothiocyanate (EXP)

17beta-estradiol (ISO)

2,3',4,4',5-Pentachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

alpha-Zearalanol (EXP)

ammonium chloride (EXP)

antirheumatic drug (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bis(2-ethylhexyl) phthalate (EXP,ISO)

bisphenol A (EXP,ISO)

cadmium atom (ISO)

cadmium dichloride (EXP,ISO)

caffeine (ISO)

carbon nanotube (ISO)

cisplatin (ISO)

copper(II) sulfate (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

cylindrospermopsin (ISO)

dibutyl phthalate (EXP)

dicrotophos (ISO)

dinophysistoxin 1 (ISO)

dioxygen (ISO)

diuron (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

ethanol (ISO)

fluoranthene (ISO)

flutamide (EXP)

formaldehyde (ISO)

gentamycin (EXP)

glafenine (EXP)

glyphosate (ISO)

graphite (EXP)

hydrogen peroxide (ISO)

lipopolysaccharide (ISO)

methylmercury chloride (ISO)

mono(2-ethylhexyl) phthalate (ISO)

N-nitrosodiethylamine (ISO)

okadaic acid (ISO)

paracetamol (EXP,ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (EXP)

phenobarbital (ISO)

phenylmercury acetate (ISO)

pregnenolone 16alpha-carbonitrile (EXP,ISO)

resveratrol (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

senecionine (ISO)

silicon dioxide (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

succimer (ISO)

tetrachloromethane (ISO)

thiram (ISO)

titanium dioxide (ISO)

trichloroethene (EXP)

triclosan (ISO)

triphenyl phosphate (ISO)

Triptolide (ISO)

triptonide (ISO)

undecane (EXP)

urethane (ISO)

valproic acid (ISO)

vincristine (ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to toxic substance (ISO)

Cellular Component

nucleoplasm (IEA,ISO)

Molecular Function

protein binding (ISO)

protein heterodimerization activity (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
2.	Cca3, the mRNA level of which transiently decreases before initiation of DNA synthesis in regenerating rat liver cells.	Hayashi Y, etal., FEBS Lett 1997 Apr 7;406(1-2):147-50.
3.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
4.	GOA pipeline	RGD automated data pipeline
5.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8889548	PMID:24076025

Genomics

Comparative Map Data

Abtb2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	110,409,672 - 110,563,488 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	110,409,627 - 110,563,487 (+)	Ensembl				GRCr8
mRatBN7.2	3	89,954,726 - 90,108,549 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	89,954,713 - 90,108,548 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	93,448,249 - 93,601,949 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	102,047,320 - 102,201,032 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	99,878,295 - 100,032,334 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	93,494,706 - 93,648,750 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	93,495,106 - 93,647,721 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	100,136,224 - 100,290,000 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	88,858,336 - 89,012,166 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	89,022,954 - 89,176,876 (+)	NCBI		Celera
RGSC_v3.1	3	88,754,763 - 88,908,594 (+)	NCBI
Cytogenetic Map	3	q32	NCBI

ABTB2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	34,150,987 - 34,358,010 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	34,150,987 - 34,358,010 (-)	Ensembl			hg38	GRCh38
GRCh37	11	34,172,534 - 34,379,557 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	34,129,111 - 34,335,378 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	11	34,129,110 - 34,335,378	NCBI
Celera	11	34,320,078 - 34,526,769 (-)	NCBI		Celera
Cytogenetic Map	11	p13	NCBI
HuRef	11	33,869,169 - 34,076,838 (-)	NCBI		HuRef
CHM1_1	11	34,171,903 - 34,378,573 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	11	34,287,990 - 34,494,746 (-)	NCBI		T2T-CHM13v2.0

Abtb2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	103,396,655 - 103,548,768 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	103,396,655 - 103,548,768 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	2	103,566,310 - 103,718,423 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	103,566,310 - 103,718,423 (+)	Ensembl			mm10	GRCm38
MGSCv37	2	103,406,467 - 103,558,580 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	2	103,367,149 - 103,519,262 (+)	NCBI		MGSCv36	mm8
Celera	2	104,814,461 - 104,967,567 (+)	NCBI		Celera
Cytogenetic Map	2	E2	NCBI
cM Map	2	54.43	NCBI

Abtb2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955422	11,913,334 - 12,081,323 (+)	Ensembl
ChiLan1.0	NW_004955422	11,913,334 - 12,082,421 (+)	NCBI	ChiLan1.0	ChiLan1.0

ABTB2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	36,375,204 - 36,583,194 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	36,380,013 - 36,588,023 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	34,127,668 - 34,335,680 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	34,006,139 - 34,212,042 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	34,015,276 - 34,211,591 (-)	Ensembl			panPan2	panpan1.1

ABTB2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	33,483,925 - 33,651,165 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	18	33,483,862 - 33,650,327 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	33,090,280 - 33,257,034 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	34,095,625 - 34,262,444 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	18	34,095,148 - 34,262,442 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	18	33,654,976 - 33,821,572 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	33,247,108 - 33,414,047 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	33,882,624 - 34,049,579 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Abtb2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	30,581,110 - 30,742,203 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936533	3,705,873 - 3,867,106 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936533	3,705,902 - 3,866,998 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ABTB2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	26,548,852 - 26,782,172 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	2	26,579,526 - 26,782,180 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	28,946,563 - 29,149,547 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ABTB2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	30,906,832 - 31,120,948 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	30,907,236 - 31,119,590 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666038	128,016,431 - 128,224,522 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Abtb2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624767	12,794,431 - 12,962,770 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624767	12,793,687 - 12,963,836 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Abtb2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	5	81,397,623 - 81,549,722 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Abtb2
1084 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	412
Count of miRNA genes:	228
Interacting mature miRNAs:	276
Transcripts:	ENSRNOT00000029922
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300178	Hrtrt4	Heart rate QTL 4	3.74		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	3	51490129	111359995	Rat
1358293	Bw38	Body weight QTL 38	6	0.0000031	body mass (VT:0001259)	body weight (CMO:0000012)	3	74364268	119364268	Rat
2301414	Kidm37	Kidney mass QTL 37		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	96509147	141509147	Rat
1582238	Bw68	Body weight QTL 68	3.2	0.0064	body mass (VT:0001259)	body weight (CMO:0000012)	3	73592512	136118980	Rat
1582239	Epfw1	Epididymal fat weight QTL 1	4.5	0.0006	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	3	73592512	136118980	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	51581665	184004958	Rat
2292591	Esta4	Estrogen-induced thymic atrophy QTL 4			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	3	67641776	167835660	Rat
1358362	Srcrt2	Stress Responsive Cort QTL 2	2.78		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	58601291	153936591	Rat
737818	Hcar12	Hepatocarcinoma resistance QTL 12	2.6		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	3	49872657	138829559	Rat
1582218	Bw74	Body weight QTL 74	3.9	0.0021	body mass (VT:0001259)	body weight (CMO:0000012)	3	73592512	136118980	Rat
1582221	Kidm30	Kidney mass QTL 30	3.5	0.0008	kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	3	85062224	136118980	Rat
1582210	Bw71	Body weight QTL 71	3.3	0.0012	body mass (VT:0001259)	body weight (CMO:0000012)	3	85062224	136118980	Rat
7387306	Bw124	Body weight QTL 124	3.2	0.0003	body mass (VT:0001259)	body weight (CMO:0000012)	3	104545086	149545086	Rat
1300111	Rf12	Renal function QTL 12	3.78		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	3	81425008	141509147	Rat
724523	Tsu1	Thymus enlargement suppressive QTL 1	3.84		thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	3	70845569	136091483	Rat
1600376	Arunc5	Aerobic running capacity QTL 5		0.21	exercise endurance trait (VT:0002332)	longest distance run on treadmill (CMO:0001406)	3	93829559	138829559	Rat
2302273	Gluco35	Glucose level QTL 35	5.3	0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	101255536	134750886	Rat
8662816	Vetf4	Vascular elastic tissue fragility QTL 4	4		renal artery integrity trait (VT:0010642)	number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)	3	79649560	177741895	Rat
1581503	Cm58	Cardiac mass QTL 58	2.7	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	96509147	141509147	Rat
2292613	Ept16	Estrogen-induced pituitary tumorigenesis QTL 16	8.3		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	67641995	130815812	Rat
631649	Bp123	Blood pressure QTL 123	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	110225882	155225882	Rat
631841	Niddm39	Non-insulin dependent diabetes mellitus QTL 39	3.36		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	70311536	115311536	Rat
631200	Cm25	Cardiac mass QTL 25	4.8	0.0001	heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	3	81541464	126563126	Rat
12879848	Bw181	Body weght QTL 181		0.015	body mass (VT:0001259)	body weight (CMO:0000012)	3	90755164	141509147	Rat
1354597	Kidm13	Kidney mass QTL 13	2.9		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	3	42158111	124558371	Rat
1358885	Bp251	Blood pressure QTL 251	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	1	141509147	Rat
1581546	Pur13	Proteinuria QTL 13	2.93	0.0335	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	3	98651826	167012663	Rat
1354604	Bw36	Body weight QTL 36	2.9		body mass (VT:0001259)	body weight (CMO:0000012)	3	42158111	124558371	Rat
1358888	Bp264	Blood pressure QTL 264	4.43		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	5675975	141509147	Rat
1358186	Ept2	Estrogen-induced pituitary tumorigenesis QTL 2	8.3		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	67641995	130815812	Rat

Markers in Region

D3Got47

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	3	110,532,240 - 110,532,449 (+)	Marker Load Pipeline
mRatBN7.2	3	90,077,299 - 90,077,508 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	93,617,497 - 93,617,705	NCBI	Rnor6.0
Rnor_5.0	3	100,259,015 - 100,259,223	UniSTS	Rnor5.0
RGSC_v3.4	3	88,980,919 - 88,981,128	RGD	RGSC3.4
RGSC_v3.4	3	88,980,920 - 88,981,128	UniSTS	RGSC3.4
Celera	3	89,145,464 - 89,145,672	UniSTS
RGSC_v3.1	3	88,877,347 - 88,877,556	RGD
Cytogenetic Map	3	q32	UniSTS

RH131288

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	90,108,535 - 90,108,753 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	93,648,737 - 93,648,954	NCBI	Rnor6.0
Rnor_5.0	3	100,289,987 - 100,290,204	UniSTS	Rnor5.0
RGSC_v3.4	3	89,012,152 - 89,012,369	UniSTS	RGSC3.4
Celera	3	89,176,863 - 89,177,080	UniSTS
RH 3.4 Map	3	721.19	UniSTS
Cytogenetic Map	3	q32	UniSTS

RH134100

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	90,108,245 - 90,108,432 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	93,648,447 - 93,648,633	NCBI	Rnor6.0
Rnor_5.0	3	100,289,697 - 100,289,883	UniSTS	Rnor5.0
RGSC_v3.4	3	89,011,862 - 89,012,048	UniSTS	RGSC3.4
Celera	3	89,176,573 - 89,176,759	UniSTS
RH 3.4 Map	3	719.41	UniSTS
Cytogenetic Map	3	q32	UniSTS

AW539457

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	90,108,264 - 90,108,375 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	93,648,466 - 93,648,576	NCBI	Rnor6.0
Rnor_5.0	3	100,289,716 - 100,289,826	UniSTS	Rnor5.0
RGSC_v3.4	3	89,011,881 - 89,011,991	UniSTS	RGSC3.4
Celera	3	89,176,592 - 89,176,702	UniSTS
Cytogenetic Map	3	q32	UniSTS

BM384314

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	89,953,725 - 89,953,937 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	97,029,851 - 97,030,062	NCBI	Rnor6.0
Rnor_6.0	3	93,493,706 - 93,493,917	NCBI	Rnor6.0
Rnor_5.0	3	103,650,167 - 103,650,378	UniSTS	Rnor5.0
Rnor_5.0	3	100,135,224 - 100,135,435	UniSTS	Rnor5.0
RGSC_v3.4	3	88,857,349 - 88,857,560	UniSTS	RGSC3.4
Celera	3	89,021,954 - 89,022,165	UniSTS
RH 3.4 Map	3	717.61	UniSTS
Cytogenetic Map	3	q32	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	161	91	90	59	92	59	6	356	192	11	140	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_134403	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB000216	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BQ203018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CB609664	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CB714885	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473949	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CV110237	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DY545654	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ233420	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000029922 ⟹ ENSRNOP00000038218

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	110,409,627 - 110,562,418 (+)	Ensembl
mRatBN7.2 Ensembl	3	89,954,713 - 90,107,479 (+)	Ensembl
Rnor_6.0 Ensembl	3	93,495,106 - 93,647,680 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000085760 ⟹ ENSRNOP00000069124

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	110,409,627 - 110,563,487 (+)	Ensembl
mRatBN7.2 Ensembl	3	89,954,713 - 90,108,548 (+)	Ensembl
Rnor_6.0 Ensembl	3	93,495,106 - 93,647,721 (+)	Ensembl

RefSeq Acc Id:

NM_134403 ⟹ NP_599230

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	110,409,672 - 110,563,488 (+)	NCBI
mRatBN7.2	3	89,954,726 - 90,108,549 (+)	NCBI
Rnor_6.0	3	93,494,706 - 93,648,750 (+)	NCBI
Rnor_5.0	3	100,136,224 - 100,290,000 (+)	NCBI
RGSC_v3.4	3	88,858,336 - 89,012,166 (+)	RGD
Celera	3	89,022,954 - 89,176,876 (+)	NCBI

Sequence:

show sequence

CGCTTTCTCACCGGCTGGTCCGGGACGGATAGCCGGCGCCTCGCTCTTCGGTGACCGCCCCATT
CTCTCGGGATTCCTTCTCTGTGGTGACGGACGCTCTAGACGCTCGGTAAGGGAAGCTGAGGCTG
GCGGCGGGAGTTCAGAGGAGGAGCGCGGAGAGGTTGCTCGCTGACAGCGGCGCGGCTGGACGCG
GACGGCGTCGGGCTCTGGCCGGCTGAGAGCTTCGCCCACCTTCCCCGCGGCCTGTGCGCAGGCG
ATGCTGCGGCCCCGAGGCGCGGCGCGGCGAGCAGGGAGGGCGCCTCCGAGAGCCTAGAGCTGGT
TTCCGTCCTCTTCCCCGGGGCAAGTGGGCATGGAACAGTGAGAGCCCCTCGCTCGGCGAGGCCG
CGCGCGGAGGCTCCCCATGGCCGGGACGTACAGCTCCACATTGAAGACTCTGGAGGACTTGACC
TTGGACTCCGGGTATGGGGCCGGCGACTCCTGCCGCTCGCTCAGCCTTTCGTCTTCCAAGTCCA
ACTCGCAGGCGCTCAACTCTTCGGCGCCGCAGCACCGCGGGGCGGCCTGGTGGTGCTACTCCGG
CTCCATGAACAGCCGCCACAACAGCTGGGACACCGTGAACACAGTGCTGCCCGAGGATCCCGAA
GTGGCCGACCTCTTCTCGCGCTGCCCGCGGCTCCCGGAGCTAGAGGAGTTCCCTTGGACCGAGG
GAGACGTGGCTCGGGTGCTCCGCAAAAGCGTCGGCGGCCGGAGGCTGCCCTCATTCTCCGCCGA
GGCTGTGAGGCGCTTGGCCGGACTCCTCCGCCGGGCGCTCATCCGCGTGGCCCGGGAGGCGCAG
CGCCTAAGCGTGCTGCACGCCAAGTGTACCCGCTTCGAGGTGCAGAGTGCGGTGCGCCTGGTGC
ACAGCTGGGCGCTGGCCGAGAGCTGCGCGCTGGCAGCGGTCAAGGCGTTGTCCCTCTATAGCAT
GAGCGCTGGCGATGGGCTGCGCCGCGGCAAGTCGGCACGCTGCGGCCTCACTTTCTCCGTGGGC
CGTTTCTTCCGTTGGATGGTGGACACTCGCATCTCCGTGCGCATCCATGAGTATGCGGCCATCT
CGCTTACGGCTTGCATGGAGAACTTGGTGGAGGAGATCCGGGCTAGGGTCCTGGCGAGTCAGAG
CCCTGATGGCGGAGGGGCAGGAGGCGGAGAGGTATCCGCTGAGGCCTTGGAGATGGTCATCAAC
AACGATGCCGAGCTCTGGGGAGTCCTGCAACCCTATGAGCATCTCATCTGCGGCAAGAACGCCA
ATGGTGTCCTCTCCCTCCCTGCCTACTTCAGTCCCTACAATGGTGGGTCCCTGGGCCATGATGA
GCGAGCAGATGCCTATGCTCAGCTGGAGCTTCGGACACTGGAGCAGTCACTCCTGGCTACCTGT
GTGGGCAGCATCTCCGAGCTGAGTGATCTGGTCTCTCGAGCCATGCACCACATGCAGGGGCGCC
ACCCTCTGTGCCCAGGCACCAGCCCTGCTCGCCAGGCCCGCCAGCCACCACAGCCCATCACATG
GTCCCCCGATGCTCTCCATACACTCTACTACTTCCTGAGATGTCCACAGATGGAGTCCATGGAG
AACCCCAACCTGGATCCCCCAAGAATGACCCTGAATAATGAACGGCCCTTCATGCTGCTGCCAC
CACTGATGGAGTGGATGCGGGTGGCAATCACCTATGCAGAACACCGTCGCAGCCTCACTGTGGA
CAGTGGCGATATCCGGCAGGCAGCCCGGCTGCTGCTACCAGGCCTGGACTGCGAGCCCCGCCAG
CTCAAACCCGAGTGCTGCTTCAGTTCCTTCCGGAGGCTGGACGCTCGAGCTGCTACTGAACGCT
TCAACCAGGACCTGGGCTTCCGCATGCTCAACTGTGGGAGAACAGACCTCATCAGCCAGGCCAT
CGAGGCCCTGGGCCCAGACGGGGTGAACACAATGGATGACCAGGGTCTGACACCGCTAATGTAC
GCCTGTGCTACTGGGGATGAAGCCATGGTCCAGATGCTCATCGATGCTGGAGCAAACTTGGATA
TCCAGGTCCCAAGCAACTCTCCCAGGCATCCTTCTGTCCATCCAGACAGCAGGCACTGGACCTC
CCTGACATTCGCGGTGCTGCACGGACACATCTCTGTAGTGCAGCTGCTACTTGATGCTGGTGCC
CATGTGGAGGGCTCGGCCGTGAACAGTGGGGAGGACAGCTATGCCGAGACACCCCTTCAGCTGG
CCTCTGCAGCCGGGAACTATGAGCTGGTGAGCTTGCTACTGAGCCGAGGTGCCGACCCCCTCCT
CAGCATGCTGGAAGCCAATGGCATGGCTTCTTCCCTCCATGAGGATATGAACTGCTTCAGCCAC
TCAGCTGCCCATGGCCACAGGAATGTCTTGAGGAAGCTCCTGACTCAGCCACAGCAGGCTAAAG
CAGATGTGCTGTCCCTAGAAGAGATCTTGGCTGAGGGCGTGGAGGAAAGCGACACATCGAGCCA
GGGCAGTAGCGAGGGGCCTGTGAGGTTAAGCCGGACCCGAACGAAGGCCCTGCAGGAAGCCATG
TACTACAGTGCTGAACACGGCTACGTGGACATCACGATGGAGCTGAGGGCACTAGGTGTCCCCT
GGAAGCTGCACATCTGGATAGAGTCTCTGCGGACCTCTTTCTCACAGTCACGGTACTCGGTGGT
GCAGGGCCTCCTGAGAGATTTCAGCTCCATCAAGGAGGAGGAGTACAATGAGGAGCTGGTGACA
GAAGGCTTGCAGCTCATGTTTGACATCCTCAAGACCAGCAAAAATGACTCCGTCCTCCAGCAGC
TGGCCACCATCTTCACTCACTGCTATGGCACCAGCCCCATCCCCAGCATCCCGGAGATCCGGAA
GACCCTGCCAGCCAGGCTAGATCCTCACTTTCTGAACAACAAGGAGATGTCTGATGTAACCTTC
CTCGTGGAAGGAAAGCTGTTTTATGCACACAAAGTCCTTTTGGTGACAGCATCTAACAGGTTCA
AAACCTTAATGACCAATAAGTCAGAGCAAGATGGGGACAACAGCAAAACCATTGAGATCAGCGA
CATCAAGTACCACATCTTTCAGATGCTGATGCAGTACCTGTACTATGGAGGAACAGAGTCCATG
GAGATCCCCACGGCTGACATCCTGCAGCTCCTGTCAGCTGCCAACCTGTTCCAGCTAGATGCCC
TGCAGAGACACTGTGAGATCCTGTGCTCCCAGACCCTTAGTGTGGAGAGTGCTGTCAACACCTA
CAAATACGCCAAGATCCACAACGCCCCAGAGCTGGCCCTCTTCTGTGAAGGCTTCTTCCTCAAG
CACATGAAGGCCCTGCTGGAGCAGGATGCCTTCCGGCAGCTCATCTATGGCCGAAGCAGCAAAG
TCCAGGGCCTGGACCCACTGCAGGATCTGCAGAGCACCCTAGCTGAGCGAGTACATTCTGTCTA
CGTCACCTCCCGGGTGTGAGCCAGGGTGGATGGTGACTGCTATCTGAGGGTGTACAAAGGTCTG
TTAAAGCCAGAAACCACCAGCGACACCCCCAGTGGAGGGAGGCTTGTAGGCCTTCTGGGGTAGG
CTCTCGGGGGGTACGTCCTGCTCTTCCCCTAGATTACCCTCTGTGGTGTTGACTGATCCTGAGG
TGGAAGGAGAGTCCACTTCACTGTTGCTCGGCCAGTAACTGGCCAGGGGTGTGACGTAATTGCA
CCCTGAGGGCTACCCTGTGCCCTCTCCCCTCCAGTGGCTCAGCGTCGAGCCGATCCACCTCAGC
ACCAGCCATCCTGGCTGGGGATGTTAGGATCACAGGCATTCTTATGAATGTAGAAAGTGTCCGA
GCCCAGGCCACTGGGTGCAGGAGCCGCTATGTTTGGTTTCCTAACAGAGAGAGGCTAAGTCCTG
CCCTCCAAGCTGTGCCTTTGAAAGGGCTGGGCCCTGTTGGTGAAAACCAGACCTCCAGTGCCCT
CCCTACAAGACTACTAACGAGAGTCTGAACTGGGAATCCCTGAGCACCGGGTATGCTGGGCTAC
AGGAGCTGGCAGCCACAGGAGGCCCAGCCCCATCATGTCTGTAGGCTGAGGCAGCAGGGCTTCA
ATGGCCTCAAGTGCAGGGCGCCTTCCACTCAGGGCTGGGGTGCAAGAGCACACTTCTCACCTGG
GTTCCGTGACTCTGGGGCATGAAGGACAGGGCCTTGGTGGAAGAGAAGCTGTGTCCTCTCCCCT
CCTGTCCTCAGTCTTGGCTCCCCATCCTCTGACCTGTTTGTGGACAGACGCTGGGACAGCATCA
AGAACAGCTACCTTAGAAACTATTTATTCATCAGAAGCCCCCAGGGCTTGCAATCCTGGAACAA
TATTTTCAACTTGCTGCTTGTGCTGGATGTACAAAAGAATGAATGGTATTTTATTGCTGTAATA
TTGTATGATACTGTAACTATACCTTAATGTTGTTACTTACTGTAAATGTACTATGGTTTTATCA
ACAATAAACACTCATTAACATTGAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_599230	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	BAA19969	(Get FASTA)	NCBI Sequence Viewer
	EDL79669	(Get FASTA)	NCBI Sequence Viewer
	EDL79670	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000069124
GenBank Protein	O08764	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_599230 ⟸ NM_134403

- UniProtKB:

A0A0G2JUJ7 (UniProtKB/TrEMBL), A6HNR8 (UniProtKB/TrEMBL), A6HNR9 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAGTYSSTLKTLEDLTLDSGYGAGDSCRSLSLSSSKSNSQALNSSAPQHRGAAWWCYSGSMNSR
HNSWDTVNTVLPEDPEVADLFSRCPRLPELEEFPWTEGDVARVLRKSVGGRRLPSFSAEAVRRL
AGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAAVKALSLYSMSAGDG
LRRGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIRARVLASQSPDGGG
AGGGEVSAEALEMVINNDAELWGVLQPYEHLICGKNANGVLSLPAYFSPYNGGSLGHDERADAY
AQLELRTLEQSLLATCVGSISELSDLVSRAMHHMQGRHPLCPGTSPARQARQPPQPITWSPDAL
HTLYYFLRCPQMESMENPNLDPPRMTLNNERPFMLLPPLMEWMRVAITYAEHRRSLTVDSGDIR
QAARLLLPGLDCEPRQLKPECCFSSFRRLDARAATERFNQDLGFRMLNCGRTDLISQAIEALGP
DGVNTMDDQGLTPLMYACATGDEAMVQMLIDAGANLDIQVPSNSPRHPSVHPDSRHWTSLTFAV
LHGHISVVQLLLDAGAHVEGSAVNSGEDSYAETPLQLASAAGNYELVSLLLSRGADPLLSMLEA
NGMASSLHEDMNCFSHSAAHGHRNVLRKLLTQPQQAKADVLSLEEILAEGVEESDTSSQGSSEG
PVRLSRTRTKALQEAMYYSAEHGYVDITMELRALGVPWKLHIWIESLRTSFSQSRYSVVQGLLR
DFSSIKEEEYNEELVTEGLQLMFDILKTSKNDSVLQQLATIFTHCYGTSPIPSIPEIRKTLPAR
LDPHFLNNKEMSDVTFLVEGKLFYAHKVLLVTASNRFKTLMTNKSEQDGDNSKTIEISDIKYHI
FQMLMQYLYYGGTESMEIPTADILQLLSAANLFQLDALQRHCEILCSQTLSVESAVNTYKYAKI
HNAPELALFCEGFFLKHMKALLEQDAFRQLIYGRSSKVQGLDPLQDLQSTLAERVHSVYVTSRV

hide sequence

Ensembl Acc Id:

ENSRNOP00000069124 ⟸ ENSRNOT00000085760

Ensembl Acc Id:

ENSRNOP00000038218 ⟸ ENSRNOT00000029922

Protein Domains

BTB

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-O08764-F1-model_v2	AlphaFold	O08764	1-1009	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620724	AgrOrtholog
BioCyc Gene	G2FUF-48571	BioCyc
Ensembl Genes	ENSRNOG00000008510	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000085760	ENTREZGENE
Gene3D-CATH	1.10.20.10	UniProtKB/Swiss-Prot
	1.25.40.20	UniProtKB/Swiss-Prot
	Potassium Channel Kv1.1, Chain A	UniProtKB/Swiss-Prot
InterPro	ABTB2_BTB_POZ	UniProtKB/Swiss-Prot
	Ankyrin-BTB/POZ_domain	UniProtKB/Swiss-Prot
	Ankyrin_rpt	UniProtKB/Swiss-Prot
	Ankyrin_rpt-contain_sf	UniProtKB/Swiss-Prot
	BTB/POZ_dom	UniProtKB/Swiss-Prot
	Histone-fold	UniProtKB/Swiss-Prot
	SKP1/BTB/POZ_sf	UniProtKB/Swiss-Prot
KEGG Report	rno:171440	UniProtKB/Swiss-Prot
NCBI Gene	171440	ENTREZGENE
PANTHER	ANKYRIN REPEAT AND BTB/POZ DOMAIN-CONTAINING	UniProtKB/Swiss-Prot
	ANKYRIN REPEAT AND BTB/POZ DOMAIN-CONTAINING PROTEIN 2	UniProtKB/Swiss-Prot
Pfam	Ank	UniProtKB/Swiss-Prot
	Ank_2	UniProtKB/Swiss-Prot
	BTB	UniProtKB/Swiss-Prot
PhenoGen	Abtb2	PhenoGen
PROSITE	ANK_REP_REGION	UniProtKB/Swiss-Prot
	ANK_REPEAT	UniProtKB/Swiss-Prot
	BTB	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000008510	RatGTEx
SMART	ANK	UniProtKB/Swiss-Prot
	BTB	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF47113	UniProtKB/Swiss-Prot
	SSF48403	UniProtKB/Swiss-Prot
	SSF54695	UniProtKB/Swiss-Prot
UniProt	A0A0G2JUJ7	ENTREZGENE, UniProtKB/TrEMBL
	A6HNR8	ENTREZGENE, UniProtKB/TrEMBL
	A6HNR9	ENTREZGENE, UniProtKB/TrEMBL
	ABTB2_RAT	UniProtKB/Swiss-Prot
	F1M979_RAT	UniProtKB/TrEMBL
	O08764	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-02-17	Abtb2	ankyrin repeat and BTB domain containing 2	Abtb2	ankyrin repeat and BTB (POZ) domain containing 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-09-10	Abtb2	ankyrin repeat and BTB (POZ) domain containing 2	Cca3	Cca3 protein	Symbol and Name updated	1299863	APPROVED
2002-08-07	Cca3	Cca3 protein			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_protein	protein sequence contains 1009 amino acid residues	632483

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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