Gtf2a2 (general transcription factor 2A subunit 2) - Rat Genome Database

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Gene: Gtf2a2 (general transcription factor 2A subunit 2) Rattus norvegicus
Analyze
Symbol: Gtf2a2
Name: general transcription factor 2A subunit 2
RGD ID: 620720
Description: Predicted to enable several functions, including RNA polymerase II general transcription initiation factor activity; general transcription initiation factor binding activity; and protein dimerization activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIIA complex and transcription factor TFIID complex. Orthologous to human GTF2A2 (general transcription factor IIA subunit 2); PARTICIPATES IN RNA polymerase II transcription initiation pathway; INTERACTS WITH 4-tert-Octylphenol; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: general transcription factor IIa 2; general transcription factor IIA subunit 2; general transcription factor IIA, 2; general transcription factor IIa, 2 (12kD subunit); general transcription factor2A subunit 2; MGC188808; TFIIA-gamma; transcription initiation factor IIA gamma chain; transcription initiation factor IIA subunit 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8879,542,682 - 79,556,484 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl879,547,307 - 79,565,408 (+)EnsemblGRCr8
mRatBN7.2870,662,447 - 70,675,576 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl870,662,428 - 70,675,569 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1067,628,292 - 67,628,621 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01067,133,660 - 67,133,989 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0872,311,551 - 72,320,417 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0876,422,341 - 76,435,587 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl876,422,359 - 76,435,473 (+)Ensemblrn6Rnor6.0
Rnor_5.0876,640,681 - 76,653,942 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4874,447,866 - 74,456,735 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera871,051,449 - 71,060,316 (-)NCBICelera
RGSC_v3.1874,466,919 - 74,475,789 (+)NCBI
Cytogenetic Map8q24NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Structural insights into transcription initiation by RNA polymerase II. Grunberg S and Hahn S, Trends Biochem Sci. 2013 Dec;38(12):603-11. doi: 10.1016/j.tibs.2013.09.002. Epub 2013 Oct 11.
4. TFIIAalpha/beta-like factor is encoded by a germ cell-specific gene whose expression is up-regulated with other general transcription factors during spermatogenesis in the mouse. Han SY, etal., Biol Reprod 2001 Feb;64(2):507-17.
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
9. General transcription factor IIA-gamma increases osteoblast-specific osteocalcin gene expression via activating transcription factor 4 and runt-related transcription factor 2. Yu S, etal., J Biol Chem. 2008 Feb 29;283(9):5542-53. doi: 10.1074/jbc.M705653200. Epub 2008 Jan 2.
Additional References at PubMed
PMID:1302244   PMID:7724559   PMID:7958899   PMID:7958900   PMID:8626665   PMID:12477932   PMID:19235719   PMID:27193682  


Genomics

Comparative Map Data
Gtf2a2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8879,542,682 - 79,556,484 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl879,547,307 - 79,565,408 (+)EnsemblGRCr8
mRatBN7.2870,662,447 - 70,675,576 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl870,662,428 - 70,675,569 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1067,628,292 - 67,628,621 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01067,133,660 - 67,133,989 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0872,311,551 - 72,320,417 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0876,422,341 - 76,435,587 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl876,422,359 - 76,435,473 (+)Ensemblrn6Rnor6.0
Rnor_5.0876,640,681 - 76,653,942 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4874,447,866 - 74,456,735 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera871,051,449 - 71,060,316 (-)NCBICelera
RGSC_v3.1874,466,919 - 74,475,789 (+)NCBI
Cytogenetic Map8q24NCBI
GTF2A2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381559,638,062 - 59,657,515 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1559,638,058 - 59,657,541 (-)Ensemblhg38GRCh38
GRCh371559,930,261 - 59,949,714 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361557,718,358 - 57,736,987 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341557,718,357 - 57,736,985NCBI
Celera1536,818,236 - 36,837,689 (-)NCBICelera
Cytogenetic Map15q22.2NCBI
HuRef1536,752,262 - 36,771,682 (-)NCBIHuRef
CHM1_11560,048,219 - 60,067,695 (-)NCBICHM1_1
T2T-CHM13v2.01557,439,769 - 57,459,225 (-)NCBIT2T-CHM13v2.0
Gtf2a2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39969,919,830 - 69,930,148 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl969,919,832 - 69,930,148 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38970,012,548 - 70,022,866 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl970,012,550 - 70,022,866 (+)Ensemblmm10GRCm38
MGSCv37969,860,357 - 69,870,654 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36969,811,714 - 69,822,011 (+)NCBIMGSCv36mm8
Celera967,229,001 - 67,239,301 (+)NCBICelera
Cytogenetic Map9DNCBI
cM Map939.18NCBI
Gtf2a2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495545015,181,824 - 15,195,594 (+)NCBIChiLan1.0ChiLan1.0
GTF2A2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21648,902,349 - 48,922,048 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11553,085,842 - 53,104,641 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01538,608,360 - 38,627,156 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11556,913,452 - 56,932,051 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1556,913,452 - 56,932,052 (-)EnsemblpanPan2panpan1.1
GTF2A2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13024,502,825 - 24,522,248 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3024,484,701 - 24,522,207 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3024,476,918 - 24,496,309 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03024,671,512 - 24,691,163 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3024,671,512 - 24,691,398 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13024,597,440 - 24,616,848 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03024,679,848 - 24,699,256 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03024,867,205 - 24,886,587 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Gtf2a2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640102,788,934 - 102,803,926 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647120,636,202 - 20,652,013 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647120,636,997 - 20,651,986 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GTF2A2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1112,390,594 - 112,402,265 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11112,371,276 - 112,399,541 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21124,288,264 - 124,316,522 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GTF2A2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12623,850,483 - 23,868,477 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666048117,459,828 - 117,477,971 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gtf2a2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478112,498,702 - 12,512,810 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462478112,498,057 - 12,510,701 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Gtf2a2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1864,355,473 - 64,368,417 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Gtf2a2
267 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:170
Count of miRNA genes:124
Interacting mature miRNAs:134
Transcripts:ENSRNOT00000014706
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298065Scl16Serum cholesterol level QTL 163.8blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)83975280384752803Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)849849908118871671Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)839106363103375781Rat
1298079Activ2Activity QTL 29.50.000001voluntary movement trait (VT:0003491)rearing measurement (CMO:0001515)85076395195763951Rat
11556286Cm81Cardiac mass QTL 810.01heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)83910625884106258Rat
70161Bp62Blood pressure QTL 622.90.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)85158969999045312Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)839106363103375781Rat
61464Niddm11Non-insulin dependent diabetes mellitus QTL 113.10.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)84447792689477926Rat
4889938Bss89Bone structure and strength QTL 893.8tibia size trait (VT:0100001)tibia cortical bone volume (CMO:0001725)85899169791341052Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)839106258103375958Rat
2313088Bss75Bone structure and strength QTL 753.10.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)83910625891341052Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)861019838121662124Rat
8662823Vetf5Vascular elastic tissue fragility QTL 51.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)863404444108404444Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)835464071107982864Rat
731182Uae24Urinary albumin excretion QTL 246.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)84754141992541419Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)83910625884106258Rat
1359033Bp273Blood pressure QTL 273arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83910625884106258Rat
1331769Rf39Renal function QTL 393.871urine output (VT:0003620)timed urine volume (CMO:0000260)850763951107970527Rat
61358Bp39Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)84444783789447837Rat
1358906Bp253Blood pressure QTL 25340.0004arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)84961020494610204Rat
1358907Cm40Cardiac mass QTL 401.89heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)835464071107982864Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)855428333127966348Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)839106363114525825Rat
1582254Kidm31Kidney mass QTL 313kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)84924517894245178Rat
724540Uae8Urinary albumin excretion QTL 85urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)839106258103375958Rat
10402857Bp380Blood pressure QTL 3800.95arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)862848139107848139Rat
1358892Kidm26Kidney mass QTL 263.69kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)835464071107982864Rat
1582243Bw66Body weight QTL 663.40.0048body mass (VT:0001259)body weight (CMO:0000012)84924517894245178Rat
5684973Bss100Bone structure and strength QTL 1004.7tibia area (VT:1000281)tibia area measurement (CMO:0001382)85899169791341052Rat
61373Mcs4Mammary carcinoma susceptibility QTL 41.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)84447504389475043Rat
2313057Bss76Bone structure and strength QTL 7630.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)83910625891341052Rat
12879878Bw183Body weight QTL 1830.001body mass (VT:0001259)body weight (CMO:0000012)862848139107848139Rat
1300177Cm2Cardiac mass QTL 23.65heart mass (VT:0007028)heart weight (CMO:0000017)863141536109261840Rat
1549908Neudeg1Neurodegradation QTL 15.50nervous system integrity trait (VT:0010566)logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986)858337123103337123Rat
12879879Cm99Cardiac mass QTL 990.001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)862848139107848139Rat
2313067Bss77Bone structure and strength QTL 773.10.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)83910625891341052Rat
1331804Cm30Cardiac mass QTL 303.77443heart mass (VT:0007028)heart wet weight (CMO:0000069)862970527107970527Rat
12879880Cm100Cardiac mass QTL 1000.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)862848139107848139Rat
12879881Cm101Cardiac mass QTL 1010.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)862848139107848139Rat
12879882Am8Aortic mass QTL 80.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)862848139107848139Rat
12879883Kidm65Kidney mass QTL 650.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)862848139107848139Rat
71120Niddm21Non-insulin dependent diabetes mellitus QTL 213.73blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)866992095111992095Rat
1358912Bw51Body weight QTL 512.95body mass (VT:0001259)body weight (CMO:0000012)860248093105248093Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)879394435132782436Rat
2313086Bss60Bone structure and strength QTL 604.10.0001tibia length (VT:0004357)tibia length (CMO:0000450)85899169791341052Rat
2293697Bmd39Bone mineral density QTL 39femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)862848139107848139Rat
1331837Bw23Body weight QTL 234.190.00007body mass (VT:0001259)body weight (CMO:0000012)855428416107963099Rat
1331838Niddm61Non-insulin dependent diabetes mellitus QTL 613.530.0004blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)862963099107963099Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)870041301121080908Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)868690349119799881Rat
2313046Bss78Bone structure and strength QTL 783.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)83910625891341052Rat
2301402Bp316Blood pressure QTL 3160.005arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)862848139107848139Rat
631664Hcar3Hepatocarcinoma resistance QTL 32.90.0005liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)862982864107982864Rat

Markers in Region
RH128620  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2870,675,419 - 70,675,611 (+)MAPPERmRatBN7.2
Rnor_6.0876,435,325 - 76,435,516NCBIRnor6.0
Rnor_5.0876,640,752 - 76,640,943UniSTSRnor5.0
RGSC_v3.4874,456,857 - 74,457,048UniSTSRGSC3.4
Celera871,051,136 - 71,051,327UniSTS
Cytogenetic Map8q24UniSTS
BF390041  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2870,671,233 - 70,671,355 (+)MAPPERmRatBN7.2
Rnor_6.0876,431,139 - 76,431,260NCBIRnor6.0
Rnor_5.0876,645,008 - 76,645,129UniSTSRnor5.0
RGSC_v3.4874,452,671 - 74,452,792UniSTSRGSC3.4
Celera871,055,392 - 71,055,513UniSTS
Cytogenetic Map8q24UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
10 12 61 134 57 60 41 86 41 298 168 11 125 71 73 19 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001412186 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_053345 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_178067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082206 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266220 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266222 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF000944 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC168727 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209546 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228685 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000084148   ⟹   ENSRNOP00000071778
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl879,547,307 - 79,556,484 (+)Ensembl
mRatBN7.2 Ensembl870,662,456 - 70,675,569 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000085496   ⟹   ENSRNOP00000068825
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl879,547,307 - 79,556,484 (+)Ensembl
mRatBN7.2 Ensembl870,662,428 - 70,675,568 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000090951   ⟹   ENSRNOP00000080940
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl879,547,307 - 79,565,408 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000112984   ⟹   ENSRNOP00000077033
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl879,547,307 - 79,556,210 (+)Ensembl
mRatBN7.2 Ensembl870,662,428 - 70,675,302 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000115150   ⟹   ENSRNOP00000091233
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl879,547,307 - 79,556,476 (+)Ensembl
RefSeq Acc Id: NM_001412186   ⟹   NP_001399115
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8879,543,355 - 79,556,484 (+)NCBI
mRatBN7.2870,662,447 - 70,675,576 (+)NCBI
RefSeq Acc Id: NM_053345   ⟹   NP_445797
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8879,543,355 - 79,556,484 (+)NCBI
mRatBN7.2870,662,447 - 70,675,576 (+)NCBI
Rnor_6.0876,426,335 - 76,435,203 (+)NCBI
Rnor_5.0876,640,681 - 76,653,942 (-)NCBI
RGSC_v3.4874,447,866 - 74,456,735 (+)RGD
Celera871,051,449 - 71,060,316 (-)RGD
Sequence:
RefSeq Acc Id: NR_178067
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8879,543,355 - 79,556,484 (+)NCBI
mRatBN7.2870,662,447 - 70,675,576 (+)NCBI
RefSeq Acc Id: XM_039082206   ⟹   XP_038938134
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8879,543,499 - 79,556,484 (+)NCBI
mRatBN7.2870,665,433 - 70,675,576 (+)NCBI
RefSeq Acc Id: XM_063266219   ⟹   XP_063122289
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8879,542,682 - 79,556,484 (+)NCBI
RefSeq Acc Id: XM_063266220   ⟹   XP_063122290
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8879,543,479 - 79,556,484 (+)NCBI
RefSeq Acc Id: XM_063266221   ⟹   XP_063122291
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8879,542,682 - 79,553,345 (+)NCBI
RefSeq Acc Id: XM_063266222   ⟹   XP_063122292
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8879,542,682 - 79,552,438 (+)NCBI
RefSeq Acc Id: NP_445797   ⟸   NM_053345
- UniProtKB: O08950 (UniProtKB/Swiss-Prot),   A6KEU8 (UniProtKB/TrEMBL),   A6KEU9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038938134   ⟸   XM_039082206
- Peptide Label: isoform X2
- UniProtKB: O08950 (UniProtKB/Swiss-Prot),   A6KEU8 (UniProtKB/TrEMBL),   A6KEU9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000071778   ⟸   ENSRNOT00000084148
Ensembl Acc Id: ENSRNOP00000068825   ⟸   ENSRNOT00000085496
Ensembl Acc Id: ENSRNOP00000077033   ⟸   ENSRNOT00000112984
RefSeq Acc Id: NP_001399115   ⟸   NM_001412186
- UniProtKB: O08950 (UniProtKB/Swiss-Prot),   A6KEU9 (UniProtKB/TrEMBL),   A6KEU8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122289   ⟸   XM_063266219
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063122291   ⟸   XM_063266221
- Peptide Label: isoform X3
- UniProtKB: A6KEV1 (UniProtKB/TrEMBL),   B5DEM4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122292   ⟸   XM_063266222
- Peptide Label: isoform X3
- UniProtKB: A6KEV1 (UniProtKB/TrEMBL),   B5DEM4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122290   ⟸   XM_063266220
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000091233   ⟸   ENSRNOT00000115150
Ensembl Acc Id: ENSRNOP00000080940   ⟸   ENSRNOT00000090951
Protein Domains
Transcription initiation factor IIA gamma subunit C-   Transcription initiation factor IIA gamma subunit N-

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O08950-F1-model_v2 AlphaFold O08950 1-109 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696105
Promoter ID:EPDNEW_R6627
Type:multiple initiation site
Name:LOC103695118_1
Description:transcription initiation factor IIA subunit 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0876,422,353 - 76,422,413EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620720 AgrOrtholog
BioCyc Gene G2FUF-29946 BioCyc
Ensembl Genes ENSRNOG00000056701 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000085496 ENTREZGENE
  ENSRNOT00000085496.2 UniProtKB/Swiss-Prot
  ENSRNOT00000115150 ENTREZGENE
Gene3D-CATH 1.10.287.190 UniProtKB/Swiss-Prot
  2.30.18.10 UniProtKB/Swiss-Prot
InterPro TFIIA_a-hlx UniProtKB/Swiss-Prot
  TFIIA_b-brl UniProtKB/Swiss-Prot
  TFIIA_gsu UniProtKB/Swiss-Prot
  TFIIA_gsu_C UniProtKB/Swiss-Prot
  TFIIA_gsu_N UniProtKB/Swiss-Prot
KEGG Report rno:83828 UniProtKB/Swiss-Prot
NCBI Gene 83828 ENTREZGENE
PANTHER PTHR10966 UniProtKB/Swiss-Prot
Pfam TFIIA_gamma_C UniProtKB/Swiss-Prot
  TFIIA_gamma_N UniProtKB/Swiss-Prot
PhenoGen Gtf2a2 PhenoGen
PIRSF Hum_TFIIA_gamma UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000056701 RatGTEx
Superfamily-SCOP SSF50784 UniProtKB/Swiss-Prot
  Transcription factor IIA (TFIIA), alpha-helical domain UniProtKB/Swiss-Prot
UniProt A0A0G2K1B8_RAT UniProtKB/TrEMBL
  A0A8I5ZJD1_RAT UniProtKB/TrEMBL
  A0A8I5ZRD7_RAT UniProtKB/TrEMBL
  A0A8I6AF75_RAT UniProtKB/TrEMBL
  A6KEU4_RAT UniProtKB/TrEMBL
  A6KEU5_RAT UniProtKB/TrEMBL
  A6KEU8 ENTREZGENE, UniProtKB/TrEMBL
  A6KEU9 ENTREZGENE, UniProtKB/TrEMBL
  A6KEV1 ENTREZGENE, UniProtKB/TrEMBL
  B5DEM4 ENTREZGENE, UniProtKB/TrEMBL
  O08950 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-05-18 Gtf2a2  general transcription factor 2A subunit 2  Gtf2a2  general transcription factor2A subunit 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-05-04 Gtf2a2  general transcription factor2A subunit 2  Gtf2a2  general transcription factor IIA, 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-30 Gtf2a2  general transcription factor IIA, 2  Gtf2a2  general transcription factor IIa 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-12-14 Gtf2a2  general transcription factor Iia 2    general transcription factor IIa, 2 (12kD subunit)  Name updated 1299863 APPROVED
2002-08-07 Gtf2a2  general transcription factor IIa, 2 (12kD subunit)      Symbol and Name status set to provisional 70820 PROVISIONAL