Smu1 (SMU1, DNA replication regulator and spliceosomal factor) - Rat Genome Database

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Gene: Smu1 (SMU1, DNA replication regulator and spliceosomal factor) Rattus norvegicus
Analyze
Symbol: Smu1
Name: SMU1, DNA replication regulator and spliceosomal factor
RGD ID: 620694
Description: Predicted to be involved in mRNA splicing, via spliceosome and regulation of alternative mRNA splicing, via spliceosome. Predicted to be located in nuclear speck. Predicted to be part of U2-type precatalytic spliceosome. Orthologous to human SMU1 (SMU1 DNA replication regulator and spliceosomal factor); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: brain-enriched WD repeat-containing protein; brain-enriched WD-repeat protein; Bwd; DNA replication regulator and spliceosomal factor; homolog of C. elegans smu-1; Smu-1; smu-1 suppressor of mec-8 and unc-52 homolog; smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans); smu-1 suppressor of mec-8 and unc-52 protein homolog; suppressor of Mec and Unc defects 1 homolog; suppressor of Mec and Unc defects 1 homolog (C. elegans); WD40 repeat-containing protein SMU1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8560,652,680 - 60,671,251 (-)NCBIGRCr8
mRatBN7.2555,856,691 - 55,875,262 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl555,856,246 - 55,875,300 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx557,822,380 - 57,840,946 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0559,641,542 - 59,660,108 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0559,635,611 - 59,654,276 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0557,042,301 - 57,061,379 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl557,042,705 - 57,061,365 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0561,576,122 - 61,595,202 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4558,115,070 - 58,133,640 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1558,115,248 - 58,133,819 (-)NCBI
Celera554,468,882 - 54,487,453 (-)NCBICelera
Cytogenetic Map5q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Cloning and molecular characterization of a novel gene encoding a WD-repeat protein expressed in restricted areas of adult rat brain. Di Benedetto AJ, etal., Gene 2001 Jun 13;271(1):21-31.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:28781166  


Genomics

Comparative Map Data
Smu1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8560,652,680 - 60,671,251 (-)NCBIGRCr8
mRatBN7.2555,856,691 - 55,875,262 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl555,856,246 - 55,875,300 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx557,822,380 - 57,840,946 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0559,641,542 - 59,660,108 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0559,635,611 - 59,654,276 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0557,042,301 - 57,061,379 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl557,042,705 - 57,061,365 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0561,576,122 - 61,595,202 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4558,115,070 - 58,133,640 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1558,115,248 - 58,133,819 (-)NCBI
Celera554,468,882 - 54,487,453 (-)NCBICelera
Cytogenetic Map5q22NCBI
SMU1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38933,041,765 - 33,076,674 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl933,041,765 - 33,076,674 (-)EnsemblGRCh38hg38GRCh38
GRCh37933,041,763 - 33,076,672 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36933,031,850 - 33,066,714 (-)NCBINCBI36Build 36hg18NCBI36
Build 34933,037,168 - 33,066,644NCBI
Celera932,973,152 - 33,007,723 (-)NCBICelera
Cytogenetic Map9p21.1NCBI
HuRef933,000,244 - 33,034,724 (-)NCBIHuRef
CHM1_1933,041,616 - 33,076,467 (-)NCBICHM1_1
T2T-CHM13v2.0933,058,326 - 33,097,983 (-)NCBIT2T-CHM13v2.0
Smu1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39440,735,649 - 40,757,885 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl440,736,542 - 40,757,923 (-)EnsemblGRCm39 Ensembl
GRCm38440,735,649 - 40,757,885 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl440,736,542 - 40,757,923 (-)EnsemblGRCm38mm10GRCm38
MGSCv37440,682,682 - 40,704,918 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36440,925,789 - 40,946,542 (-)NCBIMGSCv36mm8
Celera440,395,909 - 40,418,582 (-)NCBICelera
Cytogenetic Map4A5NCBI
cM Map420.46NCBI
Smu1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554722,570,340 - 2,600,146 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554722,570,248 - 2,600,551 (+)NCBIChiLan1.0ChiLan1.0
SMU1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21191,529,456 - 91,560,515 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1991,535,344 - 91,566,456 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0932,819,539 - 32,851,273 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1933,627,765 - 33,659,530 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl933,628,027 - 33,659,539 (-)Ensemblpanpan1.1panPan2
SMU1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11150,172,679 - 50,195,719 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1150,174,153 - 50,195,644 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1148,802,624 - 48,824,195 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01151,114,748 - 51,136,321 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1151,113,275 - 51,136,290 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11149,777,760 - 49,799,378 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01149,644,471 - 49,666,053 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01150,409,655 - 50,431,231 (-)NCBIUU_Cfam_GSD_1.0
Smu1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947165,067,775 - 165,091,578 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365241,615,129 - 1,639,193 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365241,615,299 - 1,639,133 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SMU1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1033,399,383 - 33,430,971 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11033,399,383 - 33,426,313 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21037,653,407 - 37,680,329 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SMU1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11247,188,919 - 47,214,320 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603844,084,954 - 44,118,204 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Smu1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473637,798,167 - 37,826,935 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473637,797,710 - 37,826,939 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Smu1
100 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:34
Count of miRNA genes:33
Interacting mature miRNAs:34
Transcripts:ENSRNOT00000010464
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)5190450412Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)572947086724018Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5228222669540447Rat
7394712Emca13Estrogen-induced mammary cancer QTL 13mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)5982326699753708Rat
1641903Alcrsp3Alcohol response QTL 3response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)51268928557689285Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)512789751113558310Rat
1600358Mamtr5Mammary tumor resistance QTL 5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51887394763873947Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)51887394774251464Rat
8552954Pigfal14Plasma insulin-like growth factor 1 level QTL 149blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)52122674466226744Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)52795544072955440Rat
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)52795544072955440Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)52851548973515489Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)52851548973515489Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)531663789131345958Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53321566578215665Rat
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53321566578215665Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53321566578215665Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)534730116104251008Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)534944474113558310Rat
1641922Alcrsp8Alcohol response QTL 8alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)53518915368564008Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)535189153141643988Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
1331773Scl26Serum cholesterol level QTL 263.065blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)54372665686724018Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)543726656129132602Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
1300115Hrtrt7Heart rate QTL 72.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)54786906290099692Rat
9589025Epfw7Epididymal fat weight QTL 720.660.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)54946360094463600Rat
7411561Bw134Body weight QTL 134240.001body mass (VT:0001259)body weight gain (CMO:0000420)54946360094463600Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)550328551141643988Rat
2303615Vencon7Ventilatory control QTL 70.001respiration trait (VT:0001943)respiration rate (CMO:0000289)55098389595983895Rat
2303574Gluco42Glucose level QTL 422blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)55349671998496719Rat
61359EaexExperimental allergic encephalomyelitis QTL x3nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)555715622100715622Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555805606132207589Rat

Markers in Region
AW556129  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2555,856,380 - 55,856,456 (+)MAPPERmRatBN7.2
Rnor_6.0557,042,433 - 57,042,508NCBIRnor6.0
Rnor_5.0561,576,254 - 61,576,329UniSTSRnor5.0
RGSC_v3.4558,114,760 - 58,114,835UniSTSRGSC3.4
Celera554,468,572 - 54,468,647UniSTS
Cytogenetic Map5q22UniSTS
RH130392  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2555,856,759 - 55,857,658 (+)MAPPERmRatBN7.2
Rnor_6.0557,042,812 - 57,043,710NCBIRnor6.0
Rnor_5.0561,576,633 - 61,577,531UniSTSRnor5.0
RGSC_v3.4558,115,139 - 58,116,037UniSTSRGSC3.4
Celera554,468,951 - 54,469,849UniSTS
Cytogenetic Map5q22UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000010464   ⟹   ENSRNOP00000010463
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl555,856,246 - 55,875,300 (-)Ensembl
Rnor_6.0 Ensembl557,042,705 - 57,061,365 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000105273   ⟹   ENSRNOP00000094346
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl555,856,379 - 55,875,293 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000115984   ⟹   ENSRNOP00000078195
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl555,856,246 - 55,874,066 (-)Ensembl
RefSeq Acc Id: NM_057195   ⟹   NP_476543
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8560,652,680 - 60,671,251 (-)NCBI
mRatBN7.2555,856,691 - 55,875,262 (-)NCBI
Rnor_6.0557,042,743 - 57,061,313 (-)NCBI
Rnor_5.0561,576,122 - 61,595,202 (-)NCBI
RGSC_v3.4558,115,070 - 58,133,640 (-)RGD
Celera554,468,882 - 54,487,453 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_476543 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAK33013 (Get FASTA)   NCBI Sequence Viewer  
  EDL98642 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000010463
  ENSRNOP00000010463.3
  ENSRNOP00000078195.1
  ENSRNOP00000094346.1
GenBank Protein Q99M63 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_476543   ⟸   NM_057195
- UniProtKB: Q99M63 (UniProtKB/Swiss-Prot),   A0A8I5YCN7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000010463   ⟸   ENSRNOT00000010464
RefSeq Acc Id: ENSRNOP00000094346   ⟸   ENSRNOT00000105273
RefSeq Acc Id: ENSRNOP00000078195   ⟸   ENSRNOT00000115984
Protein Domains
CTLH   LisH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q99M63-F1-model_v2 AlphaFold Q99M63 1-513 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693636
Promoter ID:EPDNEW_R4160
Type:initiation region
Name:Smu1_1
Description:SMU1, DNA replication regulator and spliceosomal factor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0557,061,344 - 57,061,404EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620694 AgrOrtholog
BioCyc Gene G2FUF-41587 BioCyc
Ensembl Genes ENSRNOG00000007671 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000010464 ENTREZGENE
  ENSRNOT00000010464.5 UniProtKB/TrEMBL
  ENSRNOT00000105273.1 UniProtKB/TrEMBL
  ENSRNOT00000115984.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro CTLH_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G-protein_beta_WD-40_rep UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LisH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SMU1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:117541 UniProtKB/Swiss-Prot
NCBI Gene 117541 ENTREZGENE
PANTHER PTHR22848 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40 REPEAT-CONTAINING PROTEIN SMU1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam LisH_TPL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Smu1 PhenoGen
PRINTS GPROTEINBRPT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE CTLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LISH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD_REPEATS_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000007671 RatGTEx
SMART CTLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LisH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5YCN7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AJD8_RAT UniProtKB/TrEMBL
  A6IIS2_RAT UniProtKB/TrEMBL
  G3V702_RAT UniProtKB/TrEMBL
  Q99M63 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-09-15 Smu1  SMU1, DNA replication regulator and spliceosomal factor  Smu1  DNA replication regulator and spliceosomal factor  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-06-03 Smu1  DNA replication regulator and spliceosomal factor  Smu1  smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Smu1  smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)    suppressor of Mec and Unc defects 1 homolog (C. elegans)  Name updated 1299863 APPROVED
2004-02-11 Smu1  suppressor of Mec and Unc defects 1 homolog (C. elegans)  Smu-1  homolog of C. elegans smu-1  Symbol and Name updated to reflect Human and Mouse nomenclature 625702 APPROVED
2002-08-07 Smu-1  homolog of C. elegans smu-1      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_domains contains four WD amino acid motifs 724659
gene_expression highly expressed in the Purkinje and granule neurons of the cerebellum, the pyramidal cells of the hippocampus, and the dentate gyrus 724659
gene_transcript mRNA 1.8 and 2.2 kb in size; longer one has two RNA instability signals (AUUUA) 724659