Hmgn2 (high mobility group nucleosomal binding domain 2) - Rat Genome Database

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Gene: Hmgn2 (high mobility group nucleosomal binding domain 2) Rattus norvegicus
Analyze
Symbol: Hmgn2 (Ensembl: Hmgn2-ps4)
Name: high mobility group nucleosomal binding domain 2 (Ensembl:high mobility group nucleosomal binding domain 2, pseudogene 4)
RGD ID: 620649
Description: Predicted to enable chromatin binding activity. Predicted to be involved in antimicrobial humoral immune response mediated by antimicrobial peptide and chromatin organization. Predicted to act upstream of or within negative regulation of transcription by RNA polymerase II and regulation of development, heterochronic. Predicted to be located in cytoplasm; extracellular space; and female germ cell nucleus. Predicted to be active in nucleus. Orthologous to human HMGN2 (high mobility group nucleosomal binding domain 2); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: high mobility group nucleosome binding domain 2; high mobility group nucleosome-binding domain-containing protein 2; high mobility group protein 17; high-mobility group nucleosome-binding domain-containing protein 2; Hmg17; MGC116347; MGC124667; non-histone chromosomal protein HMG-17
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Hmgn2-ps3   Hmgn2-ps4  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85151,475,907 - 151,479,361 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5151,475,909 - 151,479,397 (-)EnsemblGRCr8
mRatBN7.25146,192,126 - 146,195,580 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5146,192,126 - 146,195,521 (-)EnsemblmRatBN7.2
mRatBN7.2 Ensembl1630,622,845 - 30,634,512 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5148,895,254 - 148,898,709 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05150,664,873 - 150,668,328 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05150,651,441 - 150,654,896 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05152,195,359 - 152,198,813 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5152,195,361 - 152,198,813 (-)Ensemblrn6Rnor6.0
Rnor_5.05155,878,876 - 155,881,362 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45152,712,158 - 152,715,493 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5144,612,205 - 144,615,712 (-)NCBICelera
RGSC_v3.15152,722,662 - 152,722,956 (-)NCBI
Cytogenetic Map5q36NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3-dimethoxynaphthalene-1,4-dione  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (EXP,ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
beta-lapachone  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
Brodifacoum  (EXP)
buspirone  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
carmustine  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (EXP,ISO)
choline  (ISO)
chromium atom  (ISO)
chromium(6+)  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (ISO)
copper(II) sulfate  (ISO)
corticosterone  (EXP)
Cuprizon  (EXP)
DDE  (ISO)
dexamethasone  (ISO)
diallyl trisulfide  (ISO)
diarsenic trioxide  (ISO)
diazinon  (ISO)
dibenz[a,h]anthracene  (ISO)
diuron  (EXP)
doxorubicin  (ISO)
enzyme inhibitor  (ISO)
ethanol  (ISO)
fipronil  (EXP)
flutamide  (EXP)
folic acid  (ISO)
genistein  (ISO)
indometacin  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
leflunomide  (EXP,ISO)
levofloxacin  (EXP)
lipopolysaccharide  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
methidathion  (ISO)
N-nitrosodiethylamine  (ISO)
ozone  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
PhIP  (EXP)
pirinixic acid  (ISO)
potassium dichromate  (ISO)
propanal  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
sodium arsenite  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
tetrachloromethane  (ISO)
tetraphene  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
trimellitic anhydride  (ISO)
triptonide  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
tungsten  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
zearalenone  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromatin  (IEA)
chromosome  (TAS)
cytoplasm  (IEA,ISO)
extracellular space  (ISO)
nucleolus  (ISO)
nucleoplasm  (ISO)
nucleus  (IBA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Cytokine-induced down-regulation of zfm1/splicing factor-1 promotes smooth muscle cell proliferation. Cattaruzza M, etal., J Biol Chem 2002 Feb 22;277(8):6582-9.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Differential expression of the chromosomal high mobility group proteins 14 and 17 during the onset of differentiation in mammalian osteoblasts and promyelocytic leukemia cells. Shakoori AR, etal., J Cell Biochem 1993 Apr;51(4):479-87.
Additional References at PubMed
PMID:1302218   PMID:2169420   PMID:11133167   PMID:12477932   PMID:16204630   PMID:21278158   PMID:22681889   PMID:23975681   PMID:25002582  


Genomics

Comparative Map Data
Hmgn2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85151,475,907 - 151,479,361 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5151,475,909 - 151,479,397 (-)EnsemblGRCr8
mRatBN7.25146,192,126 - 146,195,580 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5146,192,126 - 146,195,521 (-)EnsemblmRatBN7.2
mRatBN7.2 Ensembl1630,622,845 - 30,634,512 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5148,895,254 - 148,898,709 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05150,664,873 - 150,668,328 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05150,651,441 - 150,654,896 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05152,195,359 - 152,198,813 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5152,195,361 - 152,198,813 (-)Ensemblrn6Rnor6.0
Rnor_5.05155,878,876 - 155,881,362 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45152,712,158 - 152,715,493 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5144,612,205 - 144,615,712 (-)NCBICelera
RGSC_v3.15152,722,662 - 152,722,956 (-)NCBI
Cytogenetic Map5q36NCBI
HMGN2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38126,472,440 - 26,476,642 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl126,472,013 - 26,478,209 (+)Ensemblhg38GRCh38
GRCh37126,798,931 - 26,803,133 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36126,671,489 - 26,675,720 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34126,483,055 - 26,486,603NCBI
Celera125,196,117 - 25,200,344 (+)NCBICelera
Cytogenetic Map1p36.11NCBI
HuRef125,053,209 - 25,057,410 (+)NCBIHuRef
CHM1_1126,911,906 - 26,916,138 (+)NCBICHM1_1
T2T-CHM13v2.0126,310,460 - 26,314,663 (+)NCBIT2T-CHM13v2.0
Hmgn2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394133,692,050 - 133,695,302 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4133,692,049 - 133,695,961 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm384133,964,739 - 133,967,991 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4133,964,738 - 133,968,650 (-)Ensemblmm10GRCm38
MGSCv374133,520,654 - 133,523,906 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv364133,236,815 - 133,240,067 (-)NCBIMGSCv36mm8
Celera4132,142,295 - 132,145,551 (-)NCBICelera
Cytogenetic Map4D2.3NCBI
cM Map466.47NCBI
Hmgn2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554525,846,085 - 5,849,996 (+)Ensembl
ChiLan1.0NW_0049554525,846,085 - 5,849,996 (+)NCBIChiLan1.0ChiLan1.0
HMGN2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21200,392,724 - 200,396,405 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11199,493,472 - 199,497,145 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0125,736,429 - 25,739,987 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1126,801,607 - 26,804,333 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl126,801,607 - 26,804,333 (+)EnsemblpanPan2panpan1.1
HMGN2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1273,579,042 - 73,582,786 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl273,579,042 - 73,610,696 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha270,155,762 - 70,159,506 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0274,142,182 - 74,145,929 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl274,139,249 - 74,174,423 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1270,967,003 - 70,970,745 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0271,972,747 - 71,976,493 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0272,976,197 - 72,979,941 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
HMGN2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl683,858,177 - 83,861,905 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1683,857,114 - 83,861,907 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2677,401,654 - 77,406,199 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HMGN2
(Chlorocebus sabaeus - green monkey)		 No map positions available.
Hmgn2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476410,477,276 - 10,480,980 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Hmgn2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1124,270,168 - 24,273,432 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Hmgn2
14 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:73
Count of miRNA genes:66
Interacting mature miRNAs:68
Transcripts:ENSRNOT00000067624
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)5102105698152749382Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5130249266172190305Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)544924861153890773Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5116702075161702075Rat
1354583Despr3Despair related QTL34.980.0002locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)5132930505172190305Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5141212838172190305Rat
1300119Bp180Blood pressure QTL 1803.82arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5149642129171146538Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)599905133172190305Rat
70156Niddm30Non-insulin dependent diabetes mellitus QTL 303.98blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)5134369218156289444Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5133789363172190305Rat
1331803Rf32Renal function QTL 322.798kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)5134369199172190305Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)565089051166764498Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5136631198172190305Rat
7207486Bss109Bone structure and strength QTL 109femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)5112142946157142946Rat
7207481Bss106Bone structure and strength QTL 1067.9femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5112142946157142946Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5110770739155770739Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5133081618172190305Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
631263Cm24Cardiac mass QTL 243.5heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)5149805999162987697Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5138002522170842766Rat
1549838Bss4Bone structure and strength QTL 49.2femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)5112142946157142946Rat
1581505Rf54Renal function QTL 54kidney physiology trait (VT:0002136)kidney 20-HETE level (CMO:0001854)5133270647172190305Rat
2317753Glom24Glomerulus QTL 243.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)5141764300172190305Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5133789363172190305Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5148093485172129029Rat
1581510Cm54Cardiac mass QTL 543.40.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)5125969677172190305Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
2317056Wbc3White blood cell count QTL 32.510.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)5111236572156236572Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5131708216172190305Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5114131300159131300Rat
2293642Bss37Bone structure and strength QTL 374.640.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5125969677156302135Rat
2313096Bmd78Bone mineral density QTL 783.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)5149661912166600247Rat
7207488Bss110Bone structure and strength QTL 18.4femur strength trait (VT:0010010)femur stiffness (CMO:0001674)5112142946157142946Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5116702075161702075Rat
7207491Bss112Bone structure and strength QTL 1127femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)5112142946157142946Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5116702075161702075Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)574335621156302135Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5116702075161702075Rat
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5114131300159131300Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5133081618172190305Rat
1358187Emca1Estrogen-induced mammary cancer QTL 14.4mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)5104262817153890625Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001025624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC120071 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF329828 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC099178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC099815 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB614313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473968 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213300 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213727 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214394 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215102 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216489 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217912 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219745 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219836 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221300 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223249 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229179 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229184 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: NM_001025624   ⟹   NP_001020795
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85151,475,907 - 151,479,361 (-)NCBI
mRatBN7.25146,192,126 - 146,195,580 (-)NCBI
Rnor_6.05152,195,359 - 152,198,813 (-)NCBI
Rnor_5.05155,878,876 - 155,881,362 (-)NCBI
RGSC_v3.45152,712,158 - 152,715,493 (-)RGD
Celera5144,612,205 - 144,615,712 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001020795 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH99178 (Get FASTA)   NCBI Sequence Viewer  
  AAH99815 (Get FASTA)   NCBI Sequence Viewer  
  EDL80692 (Get FASTA)   NCBI Sequence Viewer  
  EDL80693 (Get FASTA)   NCBI Sequence Viewer  
  EDL80694 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000082813
GenBank Protein P18437 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001020795   ⟸   NM_001025624
- UniProtKB: P18437 (UniProtKB/Swiss-Prot),   Q4KLJ0 (UniProtKB/TrEMBL),   A6ISZ2 (UniProtKB/TrEMBL),   A6ISZ1 (UniProtKB/TrEMBL)
- Sequence:

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P18437-F1-model_v2 AlphaFold P18437 1-90 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694123
Promoter ID:EPDNEW_R4648
Type:multiple initiation site
Name:LOC100360316_1
Description:hypothetical protein LOC100360316
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05152,198,754 - 152,198,814EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620649 AgrOrtholog
BioCyc Gene G2FUF-39605 BioCyc
Ensembl Genes ENSRNOG00000051615 Ensembl, ENTREZGENE
  ENSRNOG00000066721 Ensembl
Ensembl Transcript ENSRNOT00000095450 ENTREZGENE
IMAGE_CLONE IMAGE:7383003 IMAGE-MGC_LOAD
  IMAGE:7929654 IMAGE-MGC_LOAD
InterPro HMGN_fam UniProtKB/Swiss-Prot
MGC_CLONE MGC:116347 IMAGE-MGC_LOAD
  MGC:124667 IMAGE-MGC_LOAD
NCBI Gene 114637 ENTREZGENE
PANTHER NON-HISTONE CHROMOSOMAL PROTEIN HMG-17 UniProtKB/Swiss-Prot
  NONHISTONE CHROMOSOMAL PROTEIN HMG UniProtKB/Swiss-Prot
Pfam HMG14_17 UniProtKB/Swiss-Prot
PhenoGen Hmgn2 PhenoGen
PRINTS NONHISHMG17 UniProtKB/Swiss-Prot
PROSITE HMG14_17 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000051615 RatGTEx
  ENSRNOG00000066721 RatGTEx
SMART HMG17 UniProtKB/Swiss-Prot
UniProt A0A0G2K9F6_RAT UniProtKB/TrEMBL
  A0A8I6AC51_RAT UniProtKB/TrEMBL
  A6ISZ1 ENTREZGENE, UniProtKB/TrEMBL
  A6ISZ2 ENTREZGENE
  A6ISZ3_RAT UniProtKB/TrEMBL
  HMGN2_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q4KLJ0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-08-04 Hmgn2  high mobility group nucleosomal binding domain 2  Hmgn2  high mobility group nucleosome binding domain 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-03-12 Hmgn2  high mobility group nucleosome binding domain 2  Hmgn2  high mobility group nucleosomal binding domain 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-11-17 Hmgn2  high mobility group nucleosomal binding domain 2    high mobility group protein 17  Name updated 1299863 APPROVED
2002-08-07 Hmgn2  high mobility group protein 17      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in osteoblasts 1302218