Opcml (opioid binding protein/cell adhesion molecule-like) - Rat Genome Database

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Pathways
Gene: Opcml (opioid binding protein/cell adhesion molecule-like) Rattus norvegicus
Analyze
Symbol: Opcml
Name: opioid binding protein/cell adhesion molecule-like
RGD ID: 620635
Description: Involved in negative regulation of glial cell proliferation; positive regulation of cell size; and positive regulation of synapse assembly. Located in apical dendrite; dendritic spine; and neuronal cell body. Is active in postsynaptic density. Human ortholog(s) of this gene implicated in ovarian cancer. Orthologous to human OPCML (opioid binding protein/cell adhesion molecule like); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: OBCAM; opioid-binding cell adhesion molecule; opioid-binding protein/cell adhesion molecule; opioid-binding protein/cell adhesion molecule-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8834,451,629 - 35,562,897 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl834,451,500 - 35,558,966 (+)EnsemblGRCr8
mRatBN7.2826,788,988 - 27,304,551 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl826,192,841 - 27,300,620 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx830,831,472 - 31,354,741 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0829,125,801 - 29,649,064 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0827,009,961 - 27,528,810 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0828,842,202 - 29,967,300 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl829,453,643 - 29,962,825 (+)Ensemblrn6Rnor6.0
Rnor_5.0828,857,932 - 29,978,200 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4827,996,301 - 28,509,065 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera828,273,156 - 28,783,272 (+)NCBICelera
RGSC_v3.1827,996,397 - 28,509,162 (+)NCBI
Cytogenetic Map8q13NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dichloroethane  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4,4'-trichlorobiphenyl  (ISO)
2-palmitoylglycerol  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
barium sulfate  (EXP)
benzo[a]pyrene  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
Butylbenzyl phthalate  (ISO)
C60 fullerene  (EXP)
ceric oxide  (EXP)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
diclofenac  (ISO)
dimethylarsinic acid  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
ethanol  (EXP,ISO)
fenvalerate  (EXP)
flavonoids  (EXP)
folic acid  (ISO)
fulvestrant  (ISO)
glyphosate  (EXP)
indometacin  (EXP)
ivermectin  (ISO)
lead(0)  (ISO)
methoxychlor  (EXP)
mono(2-ethylhexyl) phthalate  (ISO)
niclosamide  (ISO)
panobinostat  (ISO)
PCB138  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenformin  (EXP)
pioglitazone  (ISO)
rotenone  (EXP,ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
testosterone  (EXP)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)
XL147  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
2. IgLON cell adhesion molecules regulate synaptogenesis in hippocampal neurons. Hashimoto T, etal., Cell Biochem Funct. 2009 Oct;27(7):496-8. doi: 10.1002/cbf.1600.
3. Opioid-binding cell adhesion molecule (OBCAM)-related clones from a rat brain cDNA library. Lippman DA, etal., Gene 1992 Aug 15;117(2):249-54.
4. Biochemical and ultrastructural analyses of IgLON cell adhesion molecules, Kilon and OBCAM in the rat brain. Miyata S, etal., Neuroscience. 2003;117(3):645-58. doi: 10.1016/s0306-4522(02)00873-4.
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Overexpression of IgLON cell adhesion molecules changes proliferation and cell size of cortical astrocytes. Sugimoto C, etal., Cell Biochem Funct. 2012 Jul;30(5):400-5. doi: 10.1002/cbf.2813. Epub 2012 Feb 28.
Additional References at PubMed
PMID:7891157   PMID:14596858   PMID:19943852   PMID:23376485  


Genomics

Comparative Map Data
Opcml
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8834,451,629 - 35,562,897 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl834,451,500 - 35,558,966 (+)EnsemblGRCr8
mRatBN7.2826,788,988 - 27,304,551 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl826,192,841 - 27,300,620 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx830,831,472 - 31,354,741 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0829,125,801 - 29,649,064 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0827,009,961 - 27,528,810 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0828,842,202 - 29,967,300 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl829,453,643 - 29,962,825 (+)Ensemblrn6Rnor6.0
Rnor_5.0828,857,932 - 29,978,200 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4827,996,301 - 28,509,065 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera828,273,156 - 28,783,272 (+)NCBICelera
RGSC_v3.1827,996,397 - 28,509,162 (+)NCBI
Cytogenetic Map8q13NCBI
OPCML
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811132,414,981 - 133,532,501 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11132,414,977 - 133,532,501 (-)Ensemblhg38GRCh38
GRCh3711132,284,875 - 133,402,396 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611131,790,085 - 132,907,613 (-)NCBIBuild 36Build 36hg18NCBI36
Build 3411131,790,086 - 132,318,247NCBI
Celera11129,456,242 - 130,574,897 (-)NCBICelera
Cytogenetic Map11q25NCBI
HuRef11128,240,684 - 128,768,428 (-)NCBIHuRef
CHM1_111132,172,051 - 133,290,318 (-)NCBICHM1_1
T2T-CHM13v2.011132,453,523 - 133,574,050 (-)NCBIT2T-CHM13v2.0
Opcml
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39927,702,050 - 28,836,706 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl927,702,071 - 28,836,706 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38927,790,716 - 28,925,410 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl927,790,775 - 28,925,410 (+)Ensemblmm10GRCm38
MGSCv37927,598,854 - 28,732,643 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36927,540,715 - 28,674,504 (+)NCBIMGSCv36mm8
Celera925,048,809 - 26,182,472 (+)NCBICelera
Cytogenetic Map9A4NCBI
cM Map913.73NCBI
Opcml
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541233,256,352 - 34,383,243 (-)Ensembl
ChiLan1.0NW_00495541233,256,013 - 34,385,603 (-)NCBIChiLan1.0ChiLan1.0
OPCML
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29133,101,081 - 134,246,526 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111134,212,702 - 135,352,710 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011127,233,465 - 128,377,367 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111131,117,659 - 132,246,315 (-)NCBIPanPan1.1PanPan1.1panPan2
OPCML
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.152,175,002 - 2,725,878 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl52,175,075 - 2,655,602 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha51,762,971 - 2,781,251 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.051,600,357 - 2,620,428 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl51,600,450 - 2,620,421 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.151,632,492 - 2,657,700 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.051,633,356 - 2,646,280 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.051,670,829 - 2,685,911 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
LOC101971822
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947114,350,370 - 114,372,667 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493657277,755 - 100,166 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OPCML
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl959,037,714 - 60,140,839 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1959,037,711 - 60,141,162 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2965,485,634 - 65,514,812 (-)NCBISscrofa10.2Sscrofa10.2susScr3
OPCML
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11123,446,497 - 124,617,242 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1123,451,729 - 123,698,280 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660431,419,513 - 2,579,683 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Opcml
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248126,875,314 - 8,042,482 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248126,852,568 - 8,042,583 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Opcml
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1823,654,966 - 24,759,599 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Opcml
2686 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:117
Count of miRNA genes:96
Interacting mature miRNAs:103
Transcripts:ENSRNOT00000042890
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357398Slep3Serum leptin concentration QTL 33.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)81799410550763951Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)835464071107982864Rat
2317030Wbc5White blood cell count QTL 53.210.005leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)81699464261994642Rat
12880044Am9Aortic mass QTL 90.007aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)81038254055382540Rat
631648Stl5Serum triglyceride level QTL 540.0003blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)83546407171842899Rat
2317032Ginf2Gastrointestinal inflammation QTL 23.210.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)81296416557964165Rat
2301416Bp315Blood pressure QTL 3150.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)81595227960952279Rat
631842Inf1Infertility severity QTL 14.10.001seminal gland mass (VT:0010524)seminal vesicle wet weight (CMO:0001603)83154366176543661Rat
2317036Livw3Liver weight QTL 32.430.01liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)81296416557964165Rat
1358907Cm40Cardiac mass QTL 401.89heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)835464071107982864Rat
1598824Memor4Memory QTL 42.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)81799386262252873Rat
12880023Bw184Body weight QTL 1840.001body mass (VT:0001259)body weight (CMO:0000012)81038254055382540Rat
12880028Cm103Cardiac mass QTL 1030.02heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)81038254055382540Rat
2317051Aia18Adjuvant induced arthritis QTL 182.42joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)81699464261994642Rat
1358892Kidm26Kidney mass QTL 263.69kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)835464071107982864Rat
1359021Bp271Blood pressure QTL 2711.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)83412590255607752Rat
2317048Ginf1Gastrointestinal inflammation QTL 13.520.005cecum mucosa thickness (VT:0010234)enterocolitis severity score (CMO:0002138)81296416557964165Rat
2302367Slep5Serum leptin concentration QTL 53.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)81799410550763951Rat
12880025Cm102Cardiac mass QTL 1020.044heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)81038254055382540Rat

Markers in Region
D8Rat190  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2826,916,854 - 26,916,981 (+)MAPPERmRatBN7.2
Rnor_6.0829,580,453 - 29,580,579NCBIRnor6.0
Rnor_5.0829,591,143 - 29,591,269UniSTSRnor5.0
RGSC_v3.4828,124,112 - 28,124,238UniSTSRGSC3.4
RGSC_v3.4828,124,042 - 28,124,422RGDRGSC3.4
Celera828,400,137 - 28,400,263UniSTS
RGSC_v3.1828,124,209 - 28,124,335RGD
RH 3.4 Map8228.1RGD
RH 3.4 Map8228.1UniSTS
RH 2.0 Map8195.5RGD
SHRSP x BN Map818.55RGD
Cytogenetic Map8q13UniSTS
D8Rat164  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8835,464,071 - 35,464,259 (+)Marker Load Pipeline
mRatBN7.2827,205,715 - 27,205,905 (+)MAPPERmRatBN7.2
Rnor_6.0829,867,983 - 29,868,170NCBIRnor6.0
Rnor_5.0829,878,681 - 29,878,868UniSTSRnor5.0
RGSC_v3.4828,414,004 - 28,414,191RGDRGSC3.4
RGSC_v3.4828,414,005 - 28,414,192UniSTSRGSC3.4
Celera828,688,571 - 28,688,755UniSTS
RGSC_v3.1828,414,101 - 28,414,288RGD
RH 3.4 Map8229.3UniSTS
RH 3.4 Map8229.3RGD
RH 2.0 Map8186.1RGD
SHRSP x BN Map818.55RGD
Cytogenetic Map8q13UniSTS
D8Got30  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8835,423,214 - 35,423,454 (+)Marker Load Pipeline
mRatBN7.2827,164,859 - 27,165,099 (+)MAPPERmRatBN7.2
Rnor_6.0829,826,894 - 29,827,133NCBIRnor6.0
Rnor_5.0829,837,592 - 29,837,831UniSTSRnor5.0
RGSC_v3.4828,372,864 - 28,373,104RGDRGSC3.4
RGSC_v3.4828,372,865 - 28,373,104UniSTSRGSC3.4
Celera828,647,744 - 28,647,983UniSTS
RGSC_v3.1828,372,962 - 28,373,201RGD
RH 3.4 Map8229.3UniSTS
RH 3.4 Map8229.3RGD
RH 2.0 Map8224.1RGD
Cytogenetic Map8q13UniSTS
D8Got361  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2827,260,504 - 27,260,693 (+)MAPPERmRatBN7.2
Rnor_6.0829,923,260 - 29,923,446NCBIRnor6.0
Rnor_5.0829,934,125 - 29,934,311UniSTSRnor5.0
RGSC_v3.4828,469,432 - 28,469,618UniSTSRGSC3.4
Celera828,743,760 - 28,743,918UniSTS
Cytogenetic Map8q13UniSTS
RH69042  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2827,299,142 - 27,299,264 (+)MAPPERmRatBN7.2
Rnor_6.0829,961,892 - 29,962,013NCBIRnor6.0
Rnor_5.0829,972,796 - 29,972,917UniSTSRnor5.0
RGSC_v3.4828,508,143 - 28,508,264UniSTSRGSC3.4
Celera828,782,350 - 28,782,471UniSTS
Cytogenetic Map8q13UniSTS
BF410517  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2827,151,462 - 27,151,673 (+)MAPPERmRatBN7.2
Rnor_6.0829,813,625 - 29,813,835NCBIRnor6.0
Rnor_5.0829,824,121 - 29,824,331UniSTSRnor5.0
RGSC_v3.4828,358,971 - 28,359,181UniSTSRGSC3.4
Celera828,634,473 - 28,634,683UniSTS
RH 3.4 Map8230.6UniSTS
Cytogenetic Map8q13UniSTS
BF405647  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2827,121,042 - 27,121,147 (+)MAPPERmRatBN7.2
Rnor_6.0829,783,313 - 29,783,417NCBIRnor6.0
Rnor_5.0829,793,809 - 29,793,913UniSTSRnor5.0
RGSC_v3.4828,328,619 - 28,328,723UniSTSRGSC3.4
Celera828,604,030 - 28,604,134UniSTS
RH 3.4 Map8228.0UniSTS
Cytogenetic Map8q13UniSTS
G45150  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2827,121,214 - 27,121,456 (+)MAPPERmRatBN7.2
Rnor_6.0829,783,485 - 29,783,726NCBIRnor6.0
Rnor_5.0829,793,981 - 29,794,222UniSTSRnor5.0
RGSC_v3.4828,328,791 - 28,329,032UniSTSRGSC3.4
Celera828,604,202 - 28,604,443UniSTS
Cytogenetic Map8q13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
11 12 67 159 89 88 57 33 57 6 282 133 11 138 73 90 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001440069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001440070 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_053848 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595412 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595413 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595414 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595415 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595416 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595417 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595418 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264778 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264779 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264780 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC110642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M88709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M88710 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M88711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000042890   ⟹   ENSRNOP00000044106
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl827,050,696 - 27,300,620 (+)Ensembl
Rnor_6.0 Ensembl829,714,285 - 29,962,825 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000090643   ⟹   ENSRNOP00000073684
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl834,451,500 - 35,558,966 (+)Ensembl
mRatBN7.2 Ensembl826,192,841 - 27,300,620 (+)Ensembl
Rnor_6.0 Ensembl829,453,643 - 29,961,975 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000094289   ⟹   ENSRNOP00000085431
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl835,309,056 - 35,558,966 (+)Ensembl
mRatBN7.2 Ensembl826,789,434 - 27,300,620 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000137975   ⟹   ENSRNOP00000103226
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl835,048,306 - 35,558,966 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000157922   ⟹   ENSRNOP00000110858
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl835,048,306 - 35,558,576 (+)Ensembl
RefSeq Acc Id: NM_053848   ⟹   NP_446300
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8835,048,040 - 35,558,411 (+)NCBI
mRatBN7.2826,789,668 - 27,300,065 (+)NCBI
Rnor_6.0829,453,178 - 29,962,814 (+)NCBI
Rnor_5.0828,857,932 - 29,978,200 (+)NCBI
RGSC_v3.4827,996,301 - 28,509,065 (+)RGD
Celera828,273,156 - 28,783,272 (+)RGD
Sequence:
RefSeq Acc Id: XM_017595412   ⟹   XP_017450901
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8835,047,359 - 35,562,897 (+)NCBI
mRatBN7.2826,788,988 - 27,304,551 (+)NCBI
Rnor_6.0829,452,497 - 29,967,300 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017595413   ⟹   XP_017450902
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8835,047,359 - 35,562,897 (+)NCBI
mRatBN7.2826,788,988 - 27,304,551 (+)NCBI
Rnor_6.0829,452,497 - 29,967,300 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017595415   ⟹   XP_017450904
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8835,047,359 - 35,562,897 (+)NCBI
mRatBN7.2826,788,988 - 27,304,551 (+)NCBI
Rnor_6.0829,452,497 - 29,967,300 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063264778   ⟹   XP_063120848
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8834,451,629 - 35,562,897 (+)NCBI
RefSeq Acc Id: XM_063264779   ⟹   XP_063120849
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8834,451,629 - 35,562,897 (+)NCBI
RefSeq Acc Id: XM_063264780   ⟹   XP_063120850
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8834,451,629 - 35,562,897 (+)NCBI
RefSeq Acc Id: NP_446300   ⟸   NM_053848
- Peptide Label: precursor
- UniProtKB: Q01654 (UniProtKB/Swiss-Prot),   Q01653 (UniProtKB/Swiss-Prot),   P32736 (UniProtKB/Swiss-Prot),   P32735 (UniProtKB/Swiss-Prot),   A0A8I6A2A2 (UniProtKB/TrEMBL),   A6JYE6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017450901   ⟸   XM_017595412
- Peptide Label: isoform X1
- UniProtKB: Q01654 (UniProtKB/Swiss-Prot),   Q01653 (UniProtKB/Swiss-Prot),   P32736 (UniProtKB/Swiss-Prot),   P32735 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017450902   ⟸   XM_017595413
- Peptide Label: isoform X2
- UniProtKB: Q01654 (UniProtKB/Swiss-Prot),   Q01653 (UniProtKB/Swiss-Prot),   P32736 (UniProtKB/Swiss-Prot),   P32735 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017450904   ⟸   XM_017595415
- Peptide Label: isoform X4
- UniProtKB: Q01654 (UniProtKB/Swiss-Prot),   Q01653 (UniProtKB/Swiss-Prot),   P32736 (UniProtKB/Swiss-Prot),   P32735 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSRNOP00000073684   ⟸   ENSRNOT00000090643
Ensembl Acc Id: ENSRNOP00000044106   ⟸   ENSRNOT00000042890
Ensembl Acc Id: ENSRNOP00000085431   ⟸   ENSRNOT00000094289
RefSeq Acc Id: XP_063120848   ⟸   XM_063264778
- Peptide Label: isoform X3
- UniProtKB: Q01654 (UniProtKB/Swiss-Prot),   Q01653 (UniProtKB/Swiss-Prot),   P32736 (UniProtKB/Swiss-Prot),   P32735 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063120849   ⟸   XM_063264779
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063120850   ⟸   XM_063264780
- Peptide Label: isoform X6
Ensembl Acc Id: ENSRNOP00000110858   ⟸   ENSRNOT00000157922
Ensembl Acc Id: ENSRNOP00000103226   ⟸   ENSRNOT00000137975
Protein Domains
Ig-like   Ig-like C2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P32736-F1-model_v2 AlphaFold P32736 1-345 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620635 AgrOrtholog
BioCyc Gene G2FUF-31295 BioCyc
Ensembl Genes ENSRNOG00000023809 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000090643 ENTREZGENE
  ENSRNOT00000137975 ENTREZGENE
  ENSRNOT00000157922 ENTREZGENE
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot
InterPro Ig-like_dom UniProtKB/Swiss-Prot
  Ig-like_dom_sf UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Ig_I-set UniProtKB/Swiss-Prot
  Ig_sub UniProtKB/Swiss-Prot
  Ig_sub2 UniProtKB/Swiss-Prot
  IgLON_domain UniProtKB/Swiss-Prot
  Immunoglobulin UniProtKB/Swiss-Prot
KEGG Report rno:116597 UniProtKB/Swiss-Prot
NCBI Gene 116597 ENTREZGENE
PANTHER IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED UniProtKB/Swiss-Prot
  OPIOID-BINDING PROTEIN_CELL ADHESION MOLECULE UniProtKB/Swiss-Prot
Pfam I-set UniProtKB/Swiss-Prot
  Ig_3 UniProtKB/Swiss-Prot
  PF00047 UniProtKB/Swiss-Prot
PhenoGen Opcml PhenoGen
PROSITE IG_LIKE UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000023809 RatGTEx
SMART IGc2 UniProtKB/Swiss-Prot
  SM00409 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot
UniProt A0A0G2K657 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A2A2 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LIX4_RAT UniProtKB/TrEMBL
  A0ABK0LNB0_RAT UniProtKB/TrEMBL
  A6JYE4 ENTREZGENE, UniProtKB/TrEMBL
  A6JYE6 ENTREZGENE, UniProtKB/TrEMBL
  OPCM_RAT UniProtKB/Swiss-Prot
  P32735 ENTREZGENE
  P32736 ENTREZGENE
  Q01653 ENTREZGENE
  Q01654 ENTREZGENE
UniProt Secondary P32735 UniProtKB/Swiss-Prot
  Q01653 UniProtKB/Swiss-Prot
  Q01654 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Opcml  opioid binding protein/cell adhesion molecule-like    opioid-binding protein/cell adhesion molecule-like  Name updated 1299863 APPROVED
2005-01-20 Opcml  opioid-binding protein/cell adhesion molecule-like      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Opcml  opioid-binding protein/cell adhesion molecule-like      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_homology identical to OBCAM in its C-terminal 318 amino acids 727538