Advanced Search (OLGA)

Gene: Tesk1 (testis associated actin remodelling kinase 1) Rattus norvegicus

Analyze

Symbol:

Tesk1

Name:

testis associated actin remodelling kinase 1

RGD ID:

62059

Description:

Enables protein kinase binding activity; protein serine/threonine kinase activity; and protein serine/threonine kinase inhibitor activity. Involved in positive regulation of stress fiber assembly; regulation of protein localization; and spermatogenesis. Located in perinuclear region of cytoplasm. Colocalizes with cytoplasmic vesicle. Orthologous to human TESK1 (testis associated actin remodelling kinase 1); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

dual specificity testis-specific protein kinase 1; testicular protein kinase 1; testis specific protein kinase 1; testis-specific kinase 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TESK1 (testis associated actin remodelling kinase 1)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, Panther, PhylomeDB
Mus musculus (house mouse):	Tesk1 (testis specific protein kinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Tesk1 (testis associated actin remodelling kinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TESK1 (testis associated actin remodelling kinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TESK1 (testis associated actin remodelling kinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Tesk1 (testis associated actin remodelling kinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TESK1 (testis associated actin remodelling kinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TESK1 (testis associated actin remodelling kinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tesk1 (testis associated actin remodelling kinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Tesk1 (testis associated actin remodelling kinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Tesk1 (testis specific protein kinase 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	TESK1 (testis associated actin remodelling kinase 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	si:dkeyp-75h12.2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	si:dkeyp-75h12.2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-113e8.3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-113e8.3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	cdi	Alliance	DIOPT (Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	cdi	Alliance	DIOPT (OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	LOC101730247	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	62,487,763 - 62,493,492 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	62,487,763 - 62,493,492 (+)	Ensembl				GRCr8
mRatBN7.2	5	57,691,922 - 57,697,698 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	57,691,969 - 57,697,698 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	59,671,582 - 59,677,308 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	61,490,395 - 61,496,121 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	61,467,194 - 61,472,918 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	58,937,615 - 58,943,358 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	58,937,615 - 58,943,358 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	63,463,575 - 63,469,304 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	59,913,793 - 59,918,422 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	56,273,675 - 56,279,404 (+)	NCBI		Celera
RGSC_v3.1	5	59,913,971 - 59,918,601 (+)	NCBI
Cytogenetic Map	5	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4-dinitrotoluene (EXP)

2,6-dinitrotoluene (EXP)

2-hydroxypropanoic acid (ISO)

2-methylcholine (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-sulfonyldiphenol (ISO)

8-Br-cAMP (ISO)

acrylamide (ISO)

benzene (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

Bufotalin (ISO)

cadmium dichloride (EXP)

chlorpyrifos (ISO)

cobalt dichloride (ISO)

cocaine (EXP)

cyclosporin A (ISO)

DDE (ISO)

dexamethasone (ISO)

diazinon (ISO)

Dibutyl phosphate (ISO)

doxorubicin (ISO)

erythrosin B (EXP)

fenthion (ISO)

folic acid (ISO)

folpet (ISO)

FR900359 (ISO)

indometacin (ISO)

menadione (ISO)

methidathion (ISO)

methotrexate (ISO)

methoxyacetic acid (EXP)

okadaic acid (ISO)

paracetamol (ISO)

perfluorooctane-1-sulfonic acid (EXP)

phenobarbital (ISO)

plumbagin (EXP)

rac-lactic acid (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

Tanshinone I (ISO)

tartrazine (EXP)

testosterone (ISO)

theophylline (ISO)

thiram (ISO)

titanium dioxide (ISO)

Trapidil (EXP)

urethane (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

actin cytoskeleton organization (IBA)

establishment of vesicle localization (IEA,ISO,ISS)

negative regulation of cilium assembly (IEA,ISO,ISS)

nuclear-transcribed mRNA catabolic process, no-go decay (IEA,ISO,ISS)

podocyte cell migration (IEA,ISO,ISS)

positive regulation of protein localization to nucleus (IEA,ISO,ISS)

positive regulation of stress fiber assembly (IBA,IDA)

positive regulation of substrate adhesion-dependent cell spreading (IEA,ISO,ISS)

regulation of actin cytoskeleton organization (IEA,ISO)

regulation of protein localization (IDA)

spermatogenesis (IEP)

Cellular Component

centrosome (IEA,ISO,ISS)

cytoplasm (IBA,IDA,IEA,ISO)

cytoplasmic vesicle (IDA)

lamellipodium (IEA)

nucleus (IBA)

perinuclear region of cytoplasm (IDA,IEA)

Molecular Function

ATP binding (IEA)

kinase activity (IEA)

metal ion binding (IEA)

nucleotide binding (IEA)

protein binding (IPI,ISO)

protein kinase activity (IDA,IEA,ISO,ISS)

protein kinase binding (IPI)

protein serine kinase activity (IEA)

protein serine/threonine kinase activity (IBA,IEA,IMP)

protein serine/threonine kinase inhibitor activity (IDA)

protein serine/threonine/tyrosine kinase activity (IEA)

protein tyrosine kinase activity (IEA)

transferase activity (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Tesk1 interacts with Spry2 to abrogate its inhibition of ERK phosphorylation downstream of receptor tyrosine kinase signaling.	Chandramouli S, etal., J Biol Chem. 2008 Jan 18;283(3):1679-91. doi: 10.1074/jbc.M705457200. Epub 2007 Nov 1.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
4.	Spred1 and TESK1--two new interaction partners of the kinase MARKK/TAO1 that link the microtubule and actin cytoskeleton.	Johne C, etal., Mol Biol Cell. 2008 Apr;19(4):1391-403. doi: 10.1091/mbc.E07-07-0730. Epub 2008 Jan 23.
5.	KEGG: Kyoto Encyclopedia of Genes and Genomes	KEGG
6.	Actopaxin interacts with TESK1 to regulate cell spreading on fibronectin.	LaLonde DP, etal., J Biol Chem. 2005 Jun 3;280(22):21680-8. doi: 10.1074/jbc.M500752200. Epub 2005 Apr 6.
7.	Spatiotemporal expression of testicular protein kinase 1 after rat sciatic nerve injury.	Lou D, etal., J Mol Neurosci. 2012 May;47(1):180-91. doi: 10.1007/s12031-012-9712-x.
8.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
9.	GOA pipeline	RGD automated data pipeline
10.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
12.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
13.	Tentative Sequence Identification Numbers	Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
14.	Identification and characterization of a novel protein kinase, TESK1, specifically expressed in testicular germ cells.	Toshima J, etal., J Biol Chem 1995 Dec 29;270(52):31331-7.
15.	Binding of 14-3-3beta regulates the kinase activity and subcellular localization of testicular protein kinase 1.	Toshima JY, etal., J Biol Chem 2001 Nov 16;276(46):43471-81.

Additional References at PubMed

PMID:10207045	PMID:15489334

Genomics

Comparative Map Data

Tesk1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	62,487,763 - 62,493,492 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	62,487,763 - 62,493,492 (+)	Ensembl				GRCr8
mRatBN7.2	5	57,691,922 - 57,697,698 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	57,691,969 - 57,697,698 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	59,671,582 - 59,677,308 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	61,490,395 - 61,496,121 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	61,467,194 - 61,472,918 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	58,937,615 - 58,943,358 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	58,937,615 - 58,943,358 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	63,463,575 - 63,469,304 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	59,913,793 - 59,918,422 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	56,273,675 - 56,279,404 (+)	NCBI		Celera
RGSC_v3.1	5	59,913,971 - 59,918,601 (+)	NCBI
Cytogenetic Map	5	q22	NCBI

TESK1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	35,605,262 - 35,610,033 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	35,605,262 - 35,610,041 (+)	Ensembl			hg38	GRCh38
GRCh37	9	35,605,259 - 35,610,030 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	35,595,281 - 35,600,038 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	9	35,595,366 - 35,600,029	NCBI
Celera	9	35,538,842 - 35,543,599 (+)	NCBI		Celera
Cytogenetic Map	9	p13.3	NCBI
HuRef	9	35,561,511 - 35,565,732 (+)	NCBI		HuRef
CHM1_1	9	35,605,086 - 35,609,864 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	9	35,625,926 - 35,630,697 (+)	NCBI		T2T-CHM13v2.0

Tesk1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	43,442,277 - 43,448,075 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	43,441,939 - 43,448,064 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	4	43,442,277 - 43,448,075 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	43,441,939 - 43,448,064 (+)	Ensembl			mm10	GRCm38
MGSCv37	4	43,455,149 - 43,460,947 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	4	43,463,039 - 43,469,161 (+)	NCBI		MGSCv36	mm8
Celera	4	43,475,911 - 43,481,710 (+)	NCBI		Celera
Cytogenetic Map	4	A5	NCBI
cM Map	4	23.04	NCBI

Tesk1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955472	668,352 - 699,620 (-)	Ensembl
ChiLan1.0	NW_004955472	670,847 - 676,060 (-)	NCBI	ChiLan1.0	ChiLan1.0

TESK1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	88,977,614 - 88,982,391 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	88,983,553 - 88,988,330 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	35,456,965 - 35,461,736 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	36,260,165 - 36,264,545 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	36,258,902 - 36,264,545 (+)	Ensembl			panPan2	panpan1.1

TESK1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	11	52,166,049 - 52,170,611 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	11	52,166,276 - 52,170,309 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	11	50,734,356 - 50,738,706 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	11	53,231,692 - 53,236,046 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	11	53,231,707 - 53,235,744 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	11	51,776,354 - 51,780,701 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	11	51,759,750 - 51,764,109 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	11	52,461,910 - 52,466,261 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Tesk1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	167,068,349 - 167,072,817 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936524	3,615,927 - 3,621,474 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936524	3,615,933 - 3,620,384 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TESK1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	236,341,261 - 236,345,962 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	1	236,341,160 - 236,345,964 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	264,064,388 - 264,070,983 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TESK1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	44,985,770 - 44,990,520 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	12	44,984,687 - 44,990,183 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666038	42,094,178 - 42,100,748 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tesk1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624868	5,198,984 - 5,204,019 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624868	5,198,276 - 5,203,376 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Tesk1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	1	3,050,260 - 3,056,241 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Tesk1
24 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	195
Count of miRNA genes:	136
Interacting mature miRNAs:	150
Transcripts:	ENSRNOT00000023695
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1578776	Stresp18	Stress response QTL 18	2.9		thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	5	32751649	77751649	Rat
1298067	Scl15	Serum cholesterol level QTL 15	4.8	0.001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	38011670	83011670	Rat
1300115	Hrtrt7	Heart rate QTL 7	2.76		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	5	52665372	94894052	Rat
6907115	Mcs29	Mammary carcinoma susceptibility QTL 29			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	38004331	83004331	Rat
1549845	Scl44	Serum cholesterol level QTL 44	6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	44924861	153890773	Rat
1358353	Srcrtb2	Stress Responsive Cort Basal QTL 2	3.48	0.003	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	5	23671493	79046465	Rat
70212	Niddm25	Non-insulin dependent diabetes mellitus QTL 25	3.54		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	38207390	136631402	Rat
634305	Mamtr1	Mammary tumor resistance QTL 1		0.0001	mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	17576633	62576633	Rat
1331801	Rf33	Renal function QTL 33	4.149		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	5	48523123	134369373	Rat
1598807	Glom12	Glomerulus QTL 12	2.7		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	5	38011670	83011670	Rat
1302786	Kidm8	Kidney mass QTL 8	28.15		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	5	38011670	83011670	Rat
1331782	Rf36	Renal function QTL 36	3.296		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	39019942	102105896	Rat
6903292	Stl28	Serum triglyceride level QTL 28	2.6	0.0073	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	5	33311673	78311673	Rat
1578766	Tcas11	Tongue tumor susceptibility QTL 11	4.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	5	51657967	166600247	Rat
1578767	Stresp17	Stress response QTL 17	4.3	0.01	blood aldosterone amount (VT:0005346)	plasma aldosterone level (CMO:0000551)	5	32751649	77751649	Rat
1576312	Emca8	Estrogen-induced mammary cancer QTL 8	4.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	55124766	172190305	Rat
1641912	Alcrsp18	Alcohol response QTL 18			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	5	39985948	84985948	Rat
1576314	Eutr1	Estrogen induced uterine response QTL 1			uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	6922282	81330203	Rat
6903306	Scl35	Serum cholesterol QTL 35	2.6	0.0073	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	33311673	78311673	Rat
1576317	Eutr2	Estrogen induced uterine response QTL 2		0.01	uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	39526924	84526924	Rat
1331773	Scl26	Serum cholesterol level QTL 26	3.065		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	48523123	91770353	Rat
70189	Mcs5	Mammary carcinoma susceptibility QTL 5	10.51		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	60601597	137492949	Rat
1331771	Rf35	Renal function QTL 35	4.36965		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	10019064	91770353	Rat
61359	Eaex	Experimental allergic encephalomyelitis QTL x	3		nervous system integrity trait (VT:0010566)	post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)	5	60511627	105511627	Rat
8662454	Vetf3	Vascular elastic tissue fragility QTL 3	27.4		artery integrity trait (VT:0010639)	number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)	5	7065535	74335773	Rat
2290448	Scl54	Serum cholesterol level QTL 54	2.93		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	36460764	136631402	Rat
1331756	Rf34	Renal function QTL 34	4.16275		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	10019064	87027358	Rat
8552954	Pigfal14	Plasma insulin-like growth factor 1 level QTL 14	9		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	26023211	71023211	Rat
2316959	Gluco59	Glucose level QTL 59	4.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	56546393	101546393	Rat
1600358	Mamtr5	Mammary tumor resistance QTL 5			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	23671493	68671493	Rat

Markers in Region

RH134422

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	5	62,492,969 - 62,493,363 (+)	Marker Load Pipeline
mRatBN7.2	5	57,697,175 - 57,697,569 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	58,942,836 - 58,943,229	NCBI	Rnor6.0
Rnor_5.0	5	63,468,782 - 63,469,175	UniSTS	Rnor5.0
RGSC_v3.4	5	59,917,900 - 59,918,293	UniSTS	RGSC3.4
Celera	5	56,278,882 - 56,279,275	UniSTS
RH 3.4 Map	5	396.21	UniSTS
Cytogenetic Map	5	q22	UniSTS

RH140696

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	5	62,493,384 - 62,493,771 (+)	Marker Load Pipeline
mRatBN7.2	5	57,697,590 - 57,697,977 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	58,943,251 - 58,943,637	NCBI	Rnor6.0
Rnor_5.0	5	63,469,197 - 63,469,583	UniSTS	Rnor5.0
RGSC_v3.4	5	59,918,315 - 59,918,701	UniSTS	RGSC3.4
Celera	5	56,279,297 - 56,279,683	UniSTS
Cytogenetic Map	5	q22	UniSTS

RH141088

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	57,697,435 - 57,697,616 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	58,943,096 - 58,943,276	NCBI	Rnor6.0
Rnor_5.0	5	63,469,042 - 63,469,222	UniSTS	Rnor5.0
RGSC_v3.4	5	59,918,160 - 59,918,340	UniSTS	RGSC3.4
Celera	5	56,279,142 - 56,279,322	UniSTS
Cytogenetic Map	5	q22	UniSTS

TESK1-1

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	57,695,416 - 57,696,422 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	58,941,077 - 58,942,082	NCBI	Rnor6.0
Rnor_5.0	5	63,467,023 - 63,468,028	UniSTS	Rnor5.0
RGSC_v3.4	5	59,916,141 - 59,917,146	UniSTS	RGSC3.4
Celera	5	56,277,123 - 56,278,128	UniSTS
Cytogenetic Map	5	q22	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	163	91	90	59	92	59	6	356	192	11	142	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_031578	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC121204	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC081773	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473962	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	D50864	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000080909 ⟹ ENSRNOP00000071965

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	62,487,763 - 62,493,492 (+)	Ensembl
mRatBN7.2 Ensembl	5	57,691,969 - 57,697,698 (+)	Ensembl
Rnor_6.0 Ensembl	5	58,937,615 - 58,943,358 (+)	Ensembl

RefSeq Acc Id:

NM_031578 ⟹ NP_113766

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	62,487,763 - 62,493,492 (+)	NCBI
mRatBN7.2	5	57,691,969 - 57,697,698 (+)	NCBI
Rnor_6.0	5	58,937,615 - 58,943,358 (+)	NCBI
Rnor_5.0	5	63,463,575 - 63,469,304 (+)	NCBI
RGSC_v3.4	5	59,913,793 - 59,918,422 (+)	RGD
Celera	5	56,273,675 - 56,279,404 (+)	RGD

Sequence:

show sequence

GGGCTGTAGAGGCCTCTGCACCTCCTCCTCTGGCCTGAGGGGGGCATACCCGCGTCTACAGACG
CGGGGCGCAACCTGCCGAAAGGGGTCACACCGCTGGGCGAGAGCTAGGGGAGGAGTCACCTTGA
GAGGAGGGGTCACAATGATTAGCCGAGTCACTCTGAAAGGTCTCTTTTAGTGAAAGGAACACAA
AGAGGAGGGGGTGCAGCACTAAGGGGCTCTGGATACACACTGATGTGCCAGTGTCATCCCAAGG
AAAGGTCCCCCTGAAGGAGAGCGGGCTCCGAGGGGCAGCGGCCTTTGAGGGGGCGGGATCCTGT
CGAGGGGTGGGCTGTGACGGAGGGCGGGGCTTTCTTGCAGGTGCAGGCTTCCCCTAAGAGGGTT
ATTAGGACAAAGAAGTAGGAGGGTGGTCACCGGGCGGAGCGCAGGAATCTCAACTTTACTCAGG
GGAATGGAGATGGAGTGAGGAGGGGTCGGGCCAGGTCAGGGATGCGGAGGCCAGAGGCTCCCTA
CAGCCCTGGGTACCACGACCGGAGAAAACAGGTGTTAGCGAGCCCCGAGATTTAGGGTGTCGGG
GTCAGAAGCCCCTTGAAATGGGCAGTCGGAGTGGGGCGCAGACTGGGCAGGCAGCGGGCTTGAT
CCGTGGAGCCCAGGGCGCAGGAGAATTCGCGCCTGCAGTCAACCCTTAAGTCGTCCTGTTATTC
ACGCCCCGGCCTACGCGCCGGGACGCACCTGAGGGGGCGTGGCCGGGCCACAGCTCGGGCTCCA
AGGAGTTAACCGCAGACCCGGCCGGCCACGCCCCGGGCAGGCCGCGCAGCCTGAGCCCGGCGGC
GAAGCGGAGCAGCAGCCGCCCGCGGGGAGCCCGCCGCCGGCGCCCGGGAGCGCCGCCGCCGCCC
GGCCCAGGCCCAGGCCCAGGCCCCGCGCAGAGCGGAGAGCCGCGGCGTTCCACCAGGCCCAACT
CGCCGGCGCGGCGGGGGCGGGCCCAGGACCTTCGGCAGGTCCTCCCGGAGTCCGCCGGGCGGGA
GTCCCGGCACCCGGGATCAGGTTGGGCCGGCGCCCATGGCGAGCGCGGCCTGCCCGGGTCCCGG
GGATCCGGCCATGTGAAGCAGGCCGGGGCTGGGGGCCCGGCCATGGCCGGGGAACGGCCACCGC
TGCGGGGCCCCGGGCCCGGAGAGACTCCGGTGGAGGGGCCGGGGGGCGCAGGCGGAGGCCCGGG
CCGGGGCCGGCCCTCCTCCTACCGGGCCCTCCGCAGCGCCGTGTCCAGCCTGGCGCGCGTGGAC
GATTTCGACTGCGCAGAGAAGATCGGGGCTGGTTTCTTCTCTGAGGTCTATAAGGTTCGGCACC
GACAGTCGGGACAAGTCATGGTGCTGAAGATGAACAAGCTCCCCAGTAACCGGAGCAACACTCT
AAGGGAGGTGCAGCTGATGAACCGGCTCCGGCATCCTAACATCCTCAGGTTCATGGGGGTCTGT
GTGCACCAAGGGCAGCTGCACGCGCTTACAGAGTATATGAATGGGGGTACCCTGGAACAGCTGC
TGAGCTCCCCAGAACCCCTCTCCTGGCCAGTCAGGCTCCACCTAGCACTGGACATTGCACAAGG
CCTACGGTACCTACACGCCAAAGGTGTGTTTCACCGAGACCTCACATCCAAGAACTGTCTGGTC
CGACGGGAAGACGGAGGCTTCACAGCTGTTGTGGGTGACTTCGGACTGGCTGAAAAGATCCCTG
TGTATAGGGAAGGGGCAAGGAAGGAGCCATTGGCTGTGGTGGGCTCCCCATACTGGATGGCCCC
AGAGGTGTTGCGGGGAGAGCTGTATGATGAGAAGGCCGACGTCTTCGCCTTTGGGATTGTCCTC
TGTGAGCTCATCGCCCGAGTACCTGCAGACCCTGACTACCTACCCCGTACTGAGGACTTTGGTC
TGGATGTGCCTGCTTTTCGAACTCTGGTGGGAAATGACTGTCCGCTACCTTTCCTGCTTCTGGC
CATCCACTGCTGCAGCATGGAACCCAGCGCCCGTGCCCCTTTTACTGAAATTACCCAGCACCTG
GAACAAATCCTGGAGCAGCTGCCTGAGCCCACGCCCCTCGCCAAGATGCCCCTTGCCAAGGCTC
CCTTGACATACAATCAGGGGTCTGTTCCAAGAGGAGGTCCCTCTGCCACGCTTCCCAGGTCAGA
CCCCCGGCTCTCCCGAAGCCGGTCAGACCTCTTCCTGCCACCTTCACCAGAATCACCCCCCAGT
TGGGGGGACAATCTAACACGAGTCAACCCCTTCTCACTGCGGGAAGACCTCAGGGGTGGCAAGA
TCAAACTTCTGGACACACCCTGCAAGCCGGCCACTCCACTGCCCCTGGTGCCACCATCACCACT
GACCTCTACCCAGCTGCCCTTGGTGGCCTCTCCAGAGTCCCTGGTCCAGCCTGAGACTCCCGTC
CGCCGCTGTCGTTCACTCCCTTCATCCCCTGAGCTCCCCCGACGGATGGAAACTGCACTGCCAG
GTCCTGGCCCGTCCCCCGTGGGCCCCTCGACTGAGGAAAGGATGGACTGTGAGGGCAGCAGCCC
TGAGCCAGAGCCCCCAGGGCCGGCTCCCCAGCTGCCTCTGGCTGTGGCCACTGACAACTTCATC
AGTACGTGTTCCTCAGCCTCTCAGCCCTGGTCTGCTAGACCAGGACCTTCCCTCAATAATAACC
CCCCTGCTGTGGTGGTGAATTCCCCACAAGGATGGGCGAGGGAGCCCTGGAACCGGGCACAGCA
TAGCCTTCCCCGGGCAGCAGCCCTGGAGCGGACAGAACCCTCACCACCCCCATCAGCTCCCCGG
GAGCAGGAGGAGGGGCTGCCCTGCCCTGGCTGCTGCCTCAGCCCCTTCAGCTTTGGCTTCCTAT
CCATGTGCCCCCGCCCTACCCCAGCTGTTGCCCGCTACCGCAACTTGAACTGTGAGGCGGGCAG
TCTTCTCTGCCACCGAGGGCATCATGCCAAGCCACCCACACCCAGCCTGCAGCTGCCTGGGGCA
CGCTCTTAGCACTGAGGCCTGTGATCTCAGGCTTCCAACCTTGGCCTTCGGGATACCCTGTAAG
GACAGAGTGCACTTGCTGGACAATGCCAGCCCCAGATGGGCTGACTGGCTCTTCTCCCCGTATA
GGGGAGCCTCAGCATGGTCTCAATGGACAGAGCACTTCCTGTCCAACCCCTGGGATCACTGGAC
TAGACACAGCATTGCTGACACACAAGACTAACACGTGCAAAATATTTAAAAATATTTCAATAAA
ACTGCCTGGCTGGCTCCGGGCCATCCATCCACTCAGCGGAGCGCCCTCCCCTGACCCATCTCTA
GTTCGGGAAGTTCTTAAGGAAGGTCAAAGTCTTTTCTGGAGGCTTCTTTACTCTTCCCAAGAAT
AGTTTCTGGAGCAGCTTTCAAGCAAGCAGCAGGTCGCCAGACCAGAATCAGCCCTTAGCTGGGC
GTGCCCAAGAGTGAGGGAGTGCTGGAGGAATAGCAGTCTTGAGAATTGGCAGGCCATAGGTTAA
GGATGTAGGTCACAAGGTCTTGTTCAAGTGTCTGGAAAAATAAAGCACCAGTGAGCTCCCC

hide sequence

Protein Sequences


Protein RefSeqs	NP_113766	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH81773	(Get FASTA)	NCBI Sequence Viewer
	BAA09460	(Get FASTA)	NCBI Sequence Viewer
	EDL98735	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000071965
	ENSRNOP00000071965.1
GenBank Protein	Q63572	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_113766 ⟸ NM_031578

- UniProtKB:

Q63572 (UniProtKB/Swiss-Prot), A6IJ14 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAGERPPLRGPGPGETPVEGPGGAGGGPGRGRPSSYRALRSAVSSLARVDDFDCAEKIGAGFFS
EVYKVRHRQSGQVMVLKMNKLPSNRSNTLREVQLMNRLRHPNILRFMGVCVHQGQLHALTEYMN
GGTLEQLLSSPEPLSWPVRLHLALDIAQGLRYLHAKGVFHRDLTSKNCLVRREDGGFTAVVGDF
GLAEKIPVYREGARKEPLAVVGSPYWMAPEVLRGELYDEKADVFAFGIVLCELIARVPADPDYL
PRTEDFGLDVPAFRTLVGNDCPLPFLLLAIHCCSMEPSARAPFTEITQHLEQILEQLPEPTPLA
KMPLAKAPLTYNQGSVPRGGPSATLPRSDPRLSRSRSDLFLPPSPESPPSWGDNLTRVNPFSLR
EDLRGGKIKLLDTPCKPATPLPLVPPSPLTSTQLPLVASPESLVQPETPVRRCRSLPSSPELPR
RMETALPGPGPSPVGPSTEERMDCEGSSPEPEPPGPAPQLPLAVATDNFISTCSSASQPWSARP
GPSLNNNPPAVVVNSPQGWAREPWNRAQHSLPRAAALERTEPSPPPSAPREQEEGLPCPGCCLS
PFSFGFLSMCPRPTPAVARYRNLNCEAGSLLCHRGHHAKPPTPSLQLPGARS

hide sequence

Ensembl Acc Id:

ENSRNOP00000071965 ⟸ ENSRNOT00000080909

Protein Domains

Protein kinase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q63572-F1-model_v2	AlphaFold	Q63572	1-628	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13693672

Promoter ID:

EPDNEW_R4197

Type:

initiation region

Name:

Tesk1_2

Description:

testis-specific kinase 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R4198

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	58,937,595 - 58,937,655	EPDNEW

RGD ID:

13693673

Promoter ID:

EPDNEW_R4198

Type:

single initiation site

Name:

Tesk1_1

Description:

testis-specific kinase 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R4197

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	58,938,445 - 58,938,505	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:62059	AgrOrtholog
BioCyc Gene	G2FUF-41512	BioCyc
Ensembl Genes	ENSRNOG00000053729	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000080909	ENTREZGENE
	ENSRNOT00000080909.2	UniProtKB/Swiss-Prot
Gene3D-CATH	Phosphorylase Kinase, domain 1	UniProtKB/Swiss-Prot
	Transferase(Phosphotransferase) domain 1	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7131899	IMAGE-MGC_LOAD
InterPro	Actin_reg-Ser/Thr_kinase	UniProtKB/Swiss-Prot
	Kinase-like_dom_sf	UniProtKB/Swiss-Prot
	Prot_kinase_dom	UniProtKB/Swiss-Prot
	Protein_kinase_ATP_BS	UniProtKB/Swiss-Prot
	Ser-Thr/Tyr_kinase_cat_dom	UniProtKB/Swiss-Prot
	Tyr_kinase_AS	UniProtKB/Swiss-Prot
KEGG Report	rno:29460	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:93358	IMAGE-MGC_LOAD
NCBI Gene	29460	ENTREZGENE
PANTHER	LIM DOMAIN KINASE 1	UniProtKB/Swiss-Prot
	PTHR46485:SF3	UniProtKB/Swiss-Prot
Pfam	Pkinase_Tyr	UniProtKB/Swiss-Prot
PharmGKB	TESK1	RGD
PhenoGen	Tesk1	PhenoGen
PRINTS	TYRKINASE	UniProtKB/Swiss-Prot
PROSITE	PROTEIN_KINASE_ATP	UniProtKB/Swiss-Prot
	PROTEIN_KINASE_DOM	UniProtKB/Swiss-Prot
	PROTEIN_KINASE_TYR	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000053729	RatGTEx
Superfamily-SCOP	SSF56112	UniProtKB/Swiss-Prot
TIGR	TC218388
UniProt	A6IJ14	ENTREZGENE, UniProtKB/TrEMBL
	Q63572	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2018-03-16	Tesk1	testis associated actin remodelling kinase 1	Tesk1	testis-specific kinase 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-09-24	Tesk1	testis-specific kinase 1	Tesk1	testis specific protein kinase 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2002-06-10	Tesk1	testis specific protein kinase 1			Name updated	70584	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_expression	mRNA expressed specifically in testicular germ cells	61764
gene_homology	aa sequence shares 92% identity with human TESK1	61764
gene_process	may play a central role in spermatogenesis	61764
gene_protein	predicted protein contains 628 aa residues	61764

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message