(-)-epigallocatechin 3-gallate increases expression ISO APAF1 (Homo sapiens) 6480464 epigallocatechin gallate results in increased expression of APAF1 protein CTD PMID:15657356 (S)-naringenin increases expression ISO APAF1 (Homo sapiens) 6480464 naringenin metabolite results in increased expression of APAF1 mRNA and naringenin results in increased expression of APAF1 protein CTD PMID:27838343 and PMID:36235125 (S)-naringenin multiple interactions ISO APAF1 (Homo sapiens) 6480464 [naringenin co-treated with bisphenol A] results in increased expression of APAF1 mRNA and [naringenin metabolite co-treated with bisphenol A] results in increased expression of APAF1 mRNA CTD PMID:36235125 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane decreases expression EXP 6480464 o and p'-DDT analog results in decreased expression of APAF1 mRNA CTD PMID:22937105 1,1-dichloroethene increases expression ISO Apaf1 (Mus musculus) 6480464 vinylidene chloride results in increased expression of APAF1 mRNA CTD PMID:26682919 1,2-dimethylhydrazine decreases expression ISO Apaf1 (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in decreased expression of APAF1 mRNA CTD PMID:22206623 1,3-dinitrobenzene increases expression EXP 6480464 3-dinitrobenzene results in increased expression of APAF1 mRNA CTD PMID:24140754 17beta-estradiol affects expression ISO APAF1 (Homo sapiens) 6480464 Estradiol affects the expression of APAF1 mRNA CTD PMID:21826169 17beta-estradiol increases expression ISO APAF1 (Homo sapiens) 6480464 Estradiol analog results in increased expression of APAF1 mRNA and Estradiol analog results in increased expression of APAF1 protein CTD PMID:36460128 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of APAF1 mRNA CTD PMID:32145629 17beta-estradiol decreases expression ISO APAF1 (Homo sapiens) 6480464 Estradiol results in decreased expression of APAF1 mRNA CTD PMID:23373633 and PMID:31614463 17beta-estradiol multiple interactions ISO APAF1 (Homo sapiens) 6480464 [Estradiol co-treated with EGF protein] results in decreased expression of APAF1 mRNA CTD PMID:24758408 2,2',4,4'-Tetrabromodiphenyl ether affects expression ISO APAF1 (Homo sapiens) 6480464 2 more ... CTD PMID:27589474 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Apaf1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of APAF1 mRNA CTD PMID:23864506 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Apaf1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of APAF1 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of APAF1 mRNA CTD PMID:19520675 and PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO APAF1 (Homo sapiens) 6480464 [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in decreased expression of APAF1 mRNA CTD PMID:19684285 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO APAF1 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in decreased expression of APAF1 mRNA CTD PMID:19684285 2,4,6-tribromophenol increases expression ISO APAF1 (Homo sapiens) 6480464 2 more ... CTD PMID:31675489 2,4-D multiple interactions ISO Apaf1 (Mus musculus) 6480464 [Lipopolysaccharides co-treated with 2 more ... CTD PMID:33865415 2,4-D decreases expression ISO Apaf1 (Mus musculus) 6480464 2 more ... CTD PMID:33865415 2,4-dinitrophenol increases expression ISO APAF1 (Homo sapiens) 6480464 2 and 4-Dinitrophenol results in increased expression of APAF1 mRNA alternative form CTD PMID:17064354 2,6-dinitrotoluene affects expression EXP 6480464 2 and 6-dinitrotoluene affects the expression of APAF1 mRNA CTD PMID:21346803 2-methylcholine affects expression ISO APAF1 (Homo sapiens) 6480464 beta-methylcholine affects the expression of APAF1 mRNA CTD PMID:21179406 3,3',5,5'-tetrabromobisphenol A decreases expression ISO APAF1 (Homo sapiens) 6480464 tetrabromobisphenol A results in decreased expression of APAF1 protein CTD PMID:31675489 3-chloropropane-1,2-diol multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of APAF1 protein] and Apigenin inhibits the reaction [alpha-Chlorohydrin results in increased expression of APAF1 mRNA] CTD PMID:30107153 and PMID:33651226 3-chloropropane-1,2-diol multiple interactions ISO APAF1 (Homo sapiens) 6480464 3-methyladenine inhibits the reaction [Diosgenin inhibits the reaction [alpha-Chlorohydrin results in increased expression of APAF1 protein]] and Diosgenin inhibits the reaction [alpha-Chlorohydrin results in increased expression of APAF1 protein] CTD PMID:35149085 3-chloropropane-1,2-diol increases expression ISO APAF1 (Homo sapiens) 6480464 alpha-Chlorohydrin results in increased expression of APAF1 protein CTD PMID:35149085 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin results in increased expression of APAF1 mRNA and alpha-Chlorohydrin results in increased expression of APAF1 protein CTD PMID:30107153 and PMID:33651226 3-methyladenine multiple interactions ISO APAF1 (Homo sapiens) 6480464 3-methyladenine inhibits the reaction [Diosgenin inhibits the reaction [alpha-Chlorohydrin results in increased expression of APAF1 protein]] CTD PMID:35149085 3-methylcholanthrene increases expression EXP 6480464 Methylcholanthrene results in increased expression of APAF1 mRNA CTD PMID:23273579 4,4'-diaminodiphenylmethane increases expression EXP 6480464 4 and 4'-diaminodiphenylmethane results in increased expression of APAF1 mRNA CTD PMID:25380136 4-hydroxyphenyl retinamide increases expression ISO Apaf1 (Mus musculus) 6480464 Fenretinide results in increased expression of APAF1 mRNA CTD PMID:28973697 4-nitrophenol increases expression ISO Apaf1 (Mus musculus) 6480464 4-nitrophenol results in increased expression of APAF1 mRNA CTD PMID:34673133 4-nonylphenol affects expression EXP 6480464 4-nonylphenol affects the expression of APAF1 mRNA CTD PMID:27109770 4-nonylphenol increases expression EXP 6480464 4-nonylphenol results in increased expression of APAF1 protein CTD PMID:26804764 and PMID:27109770 4-phenylbutyric acid multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of APAF1 protein] CTD PMID:33651226 4-phenylbutyric acid decreases expression EXP 6480464 4-phenylbutyric acid results in decreased expression of APAF1 protein CTD PMID:33651226 5-aza-2'-deoxycytidine increases expression ISO Apaf1 (Mus musculus) 6480464 Decitabine results in increased expression of APAF1 mRNA CTD PMID:27915011 5-aza-2'-deoxycytidine increases expression ISO APAF1 (Homo sapiens) 6480464 Decitabine results in increased expression of APAF1 mRNA and Decitabine results in increased expression of APAF1 protein CTD PMID:15972851 and PMID:19662370 5-aza-2'-deoxycytidine multiple interactions ISO APAF1 (Homo sapiens) 6480464 TP53 protein affects the reaction [Decitabine affects the expression of APAF1 mRNA] CTD PMID:17133271 5-aza-2'-deoxycytidine affects expression ISO APAF1 (Homo sapiens) 6480464 Decitabine affects the expression of APAF1 mRNA CTD PMID:17133271 5-fluorouracil increases expression ISO APAF1 (Homo sapiens) 6480464 Fluorouracil results in increased expression of APAF1 mRNA CTD PMID:16557594 5-fluorouracil affects expression ISO APAF1 (Homo sapiens) 6480464 Fluorouracil affects the expression of APAF1 mRNA CTD PMID:34151400 6-O-methylguanine multiple interactions ISO APAF1 (Homo sapiens) 6480464 [O(6)-benzylguanine co-treated with O-(6)-methylguanine] results in decreased expression of APAF1 mRNA CTD PMID:29666243 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of APAF1 mRNA CTD PMID:24780913 7,12-dimethyltetraphene multiple interactions ISO Apaf1 (Mus musculus) 6480464 [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9 more ... CTD PMID:25478867 7,12-dimethyltetraphene decreases expression ISO Apaf1 (Mus musculus) 6480464 9 more ... CTD PMID:25478867 8-Br-cAMP decreases expression ISO APAF1 (Homo sapiens) 6480464 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of APAF1 mRNA CTD PMID:22079614 acetamide increases expression EXP 6480464 acetamide results in increased expression of APAF1 mRNA CTD PMID:31881176 acetylsalicylic acid increases response to substance ISO Apaf1 (Mus musculus) 6480464 APAF1 results in increased susceptibility to Aspirin CTD PMID:11228543 acetylsalicylic acid increases expression ISO APAF1 (Homo sapiens) 6480464 Aspirin results in increased expression of APAF1 mRNA CTD PMID:20457246 acrylamide decreases expression EXP 6480464 Acrylamide results in decreased expression of APAF1 mRNA CTD PMID:28959563 acrylamide increases expression ISO Apaf1 (Mus musculus) 6480464 Acrylamide results in increased expression of APAF1 mRNA CTD PMID:21319176 aflatoxin B1 increases expression ISO Apaf1 (Mus musculus) 6480464 Aflatoxin B1 results in increased expression of APAF1 mRNA CTD PMID:19770486 aflatoxin B1 increases expression ISO APAF1 (Homo sapiens) 6480464 Aflatoxin B1 results in increased expression of APAF1 mRNA CTD PMID:22100608 and PMID:29445054 aldehydo-D-glucose multiple interactions ISO APAF1 (Homo sapiens) 6480464 [Glucose co-treated with Deferoxamine] results in increased expression of APAF1 mRNA and Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of APAF1 mRNA] CTD PMID:33962019 all-trans-retinoic acid increases expression ISO APAF1 (Homo sapiens) 6480464 Tretinoin results in increased expression of APAF1 mRNA CTD PMID:33167477 and PMID:34742744 alloxan decreases expression EXP 6480464 Alloxan results in decreased expression of APAF1 protein CTD PMID:21982801 alloxan multiple interactions EXP 6480464 Taurine inhibits the reaction [Alloxan results in increased expression of APAF1 protein] CTD PMID:23092809 alloxan increases expression EXP 6480464 Alloxan results in increased expression of APAF1 protein CTD PMID:23092809 apigenin multiple interactions ISO APAF1 (Homo sapiens) 6480464 [polylactic acid-polyglycolic acid copolymer co-treated with Apigenin] results in increased expression of APAF1 protein CTD PMID:24070738 apigenin multiple interactions EXP 6480464 Apigenin inhibits the reaction [alpha-Chlorohydrin results in increased expression of APAF1 mRNA] CTD PMID:30107153 aristolochic acid A decreases expression ISO APAF1 (Homo sapiens) 6480464 aristolochic acid I results in decreased expression of APAF1 mRNA CTD PMID:33212167 Aroclor 1254 increases expression ISO Apaf1 (Mus musculus) 6480464 Chlorodiphenyl (54% Chlorine) results in increased expression of APAF1 protein CTD PMID:22406624 arsane increases expression ISO APAF1 (Homo sapiens) 6480464 Arsenic results in increased expression of APAF1 mRNA CTD PMID:19945496 arsane multiple interactions ISO APAF1 (Homo sapiens) 6480464 Arsenic affects the reaction [GSTO1 gene alternative form results in increased expression of APAF1 mRNA] CTD PMID:22293942 arsenic atom increases expression ISO APAF1 (Homo sapiens) 6480464 Arsenic results in increased expression of APAF1 mRNA CTD PMID:19945496 arsenic atom multiple interactions ISO APAF1 (Homo sapiens) 6480464 Arsenic affects the reaction [GSTO1 gene alternative form results in increased expression of APAF1 mRNA] CTD PMID:22293942 arsenous acid increases expression ISO APAF1 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of APAF1 protein CTD PMID:25258189 arsenous acid multiple interactions ISO APAF1 (Homo sapiens) 6480464 [Erlotinib Hydrochloride co-treated with Arsenic Trioxide] results in increased expression of APAF1 mRNA and [ruxolitinib co-treated with Arsenic Trioxide] results in increased expression of APAF1 mRNA CTD PMID:29274334 and PMID:30012499 arsenous acid increases expression EXP 6480464 Arsenic Trioxide results in increased expression of APAF1 mRNA CTD PMID:19730151 atrazine decreases expression ISO APAF1 (Homo sapiens) 6480464 Atrazine results in decreased expression of APAF1 mRNA CTD PMID:34146662 azadirachtin A increases expression ISO APAF1 (Homo sapiens) 6480464 azadirachtin results in increased expression of APAF1 protein CTD PMID:20429769 bafilomycin A1 increases expression ISO APAF1 (Homo sapiens) 6480464 bafilomycin A1 results in increased expression of APAF1 protein CTD PMID:28483490 benzene increases expression EXP 6480464 Benzene results in increased expression of APAF1 protein CTD PMID:17171516 benzo[a]pyrene decreases expression ISO APAF1 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of APAF1 mRNA CTD PMID:20064835 benzo[a]pyrene multiple interactions ISO Apaf1 (Mus musculus) 6480464 [Benzo(a)pyrene co-treated with sodium bichromate] results in increased expression of APAF1 mRNA CTD PMID:22613061 benzo[a]pyrene increases expression ISO Apaf1 (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of APAF1 mRNA CTD PMID:19770486 and PMID:21964900 benzo[a]pyrene increases expression ISO APAF1 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of APAF1 mRNA and Benzo(a)pyrene results in increased expression of APAF1 protein CTD PMID:21393351 more ... benzo[a]pyrene diol epoxide I increases expression ISO APAF1 (Homo sapiens) 6480464 7 more ... CTD PMID:28593498 bifenthrin increases expression ISO Apaf1 (Mus musculus) 6480464 bifenthrin results in increased expression of APAF1 mRNA CTD PMID:26071804 and PMID:32408700 bis(2-chloroethyl) sulfide increases expression ISO Apaf1 (Mus musculus) 6480464 Mustard Gas results in increased expression of APAF1 mRNA CTD PMID:15674843 and PMID:18955075 bis(2-ethylhexyl) phthalate multiple interactions ISO Apaf1 (Mus musculus) 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of APAF1 mRNA CTD PMID:37364641 bisphenol A decreases expression ISO APAF1 (Homo sapiens) 6480464 bisphenol A results in decreased expression of APAF1 mRNA and bisphenol A results in decreased expression of APAF1 protein CTD PMID:21277958 more ... bisphenol A multiple interactions ISO Apaf1 (Mus musculus) 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of APAF1 mRNA CTD PMID:37364641 bisphenol A multiple interactions ISO APAF1 (Homo sapiens) 6480464 [naringenin co-treated with bisphenol A] results in increased expression of APAF1 mRNA and [naringenin metabolite co-treated with bisphenol A] results in increased expression of APAF1 mRNA CTD PMID:36235125 bisphenol A increases expression ISO Apaf1 (Mus musculus) 6480464 bisphenol A results in increased expression of APAF1 mRNA CTD PMID:35598803 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of APAF1 mRNA CTD PMID:32145629 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of APAF1 mRNA CTD PMID:30816183 more ... bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of APAF1 gene CTD PMID:28505145 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of APAF1 mRNA and bisphenol A results in increased expression of APAF1 protein CTD PMID:23328667 more ... bufalin increases expression ISO APAF1 (Homo sapiens) 6480464 bufalin results in increased expression of APAF1 protein CTD PMID:27444971 butachlor decreases expression ISO Apaf1 (Mus musculus) 6480464 butachlor results in decreased expression of APAF1 mRNA CTD PMID:34351278 Butylbenzyl phthalate multiple interactions ISO Apaf1 (Mus musculus) 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of APAF1 mRNA CTD PMID:37364641 butyric acid multiple interactions ISO Apaf1 (Mus musculus) 6480464 [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9 more ... CTD PMID:25478867 cadmium dichloride increases expression ISO APAF1 (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of APAF1 protein CTD PMID:24291162 cadmium sulfide increases expression ISO APAF1 (Homo sapiens) 6480464 cadmium sulfide results in increased expression of APAF1 mRNA CTD PMID:27866839 cannabidiol increases expression ISO APAF1 (Homo sapiens) 6480464 Cannabidiol results in increased expression of APAF1 protein CTD PMID:31349651 cannabidiol multiple interactions ISO APAF1 (Homo sapiens) 6480464 [Cannabidiol co-treated with moringin] results in decreased expression of APAF1 mRNA CTD PMID:30096889 cannabidiol decreases expression ISO APAF1 (Homo sapiens) 6480464 Cannabidiol results in decreased expression of APAF1 mRNA CTD PMID:27932991 capsaicin increases expression ISO APAF1 (Homo sapiens) 6480464 Capsaicin results in increased expression of APAF1 mRNA CTD PMID:19502594 carbamazepine affects expression ISO APAF1 (Homo sapiens) 6480464 Carbamazepine affects the expression of APAF1 mRNA CTD PMID:24752500 carbon nanotube increases expression ISO APAF1 (Homo sapiens) 6480464 Nanotubes and Carbon results in increased expression of APAF1 mRNA CTD PMID:15585362 carnosic acid multiple interactions ISO Apaf1 (Mus musculus) 6480464 salvin inhibits the reaction [sodium arsenite results in increased expression of APAF1 protein] CTD PMID:29854073 casticin increases expression ISO APAF1 (Homo sapiens) 6480464 casticin results in increased expression of APAF1 protein CTD PMID:27862857 ceric oxide increases expression ISO APAF1 (Homo sapiens) 6480464 ceric oxide results in increased expression of APAF1 protein CTD PMID:24987704 chlorpyrifos decreases expression ISO Apaf1 (Mus musculus) 6480464 Chlorpyrifos results in decreased expression of APAF1 mRNA and Chlorpyrifos results in decreased expression of APAF1 protein CTD PMID:20350560 and PMID:34559034 chlorpyrifos multiple interactions ISO Apaf1 (Mus musculus) 6480464 [Chlorpyrifos co-treated with cypermethrin] results in decreased expression of APAF1 protein more ... CTD PMID:34559034 chlorpyrifos increases expression ISO Apaf1 (Mus musculus) 6480464 Chlorpyrifos results in increased expression of APAF1 mRNA CTD PMID:27737797 chlorpyrifos multiple interactions ISO APAF1 (Homo sapiens) 6480464 MitoTEMPO inhibits the reaction [Chlorpyrifos results in increased expression of APAF1 protein] CTD PMID:26435000 chlorpyrifos increases expression ISO APAF1 (Homo sapiens) 6480464 Chlorpyrifos results in increased expression of APAF1 protein CTD PMID:26435000 cholesterol multiple interactions EXP 6480464 6-hydroxy-2 more ... CTD PMID:19477266 cholesterol increases expression EXP 6480464 Cholesterol analog results in increased expression of APAF1 mRNA CTD PMID:19477266 choline multiple interactions ISO Apaf1 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of APAF1 mRNA and [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of APAF1 gene CTD PMID:20938992 cimetidine increases activity ISO APAF1 (Homo sapiens) 6480464 Cimetidine results in increased activity of APAF1 protein CTD PMID:17273750 cisplatin multiple interactions ISO APAF1 (Homo sapiens) 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of APAF1 mRNA and [trichostatin A results in increased activity of APAF1 protein] which results in increased susceptibility to Cisplatin CTD PMID:20925046 and PMID:27392435 cisplatin increases expression ISO APAF1 (Homo sapiens) 6480464 Cisplatin results in increased expression of APAF1 mRNA CTD PMID:27392435 cisplatin increases expression ISO Apaf1 (Mus musculus) 6480464 Cisplatin results in increased expression of APAF1 mRNA CTD PMID:20883750 and PMID:25270620 cobalt dichloride increases expression ISO Apaf1 (Mus musculus) 6480464 cobaltous chloride results in increased expression of APAF1 mRNA CTD PMID:24265542 cobalt dichloride multiple interactions ISO Apaf1 (Mus musculus) 6480464 [cobaltous chloride co-treated with 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole] results in increased expression of APAF1 mRNA CTD PMID:24265542 coenzyme Q10 multiple interactions ISO Apaf1 (Mus musculus) 6480464 [coenzyme Q10 co-treated with TNFSF11 protein] results in increased expression of APAF1 mRNA and [coenzyme Q10 co-treated with TNFSF11 protein] results in increased expression of APAF1 protein CTD PMID:33754447 colistin increases expression ISO Apaf1 (Mus musculus) 6480464 Colistin results in increased expression of APAF1 mRNA and Colistin results in increased expression of APAF1 protein CTD PMID:34560125 copper atom increases expression ISO Apaf1 (Mus musculus) 6480464 Copper analog results in increased expression of APAF1 protein CTD PMID:22000994 copper atom increases expression EXP 6480464 Copper results in increased expression of APAF1 protein CTD PMID:30556269 copper atom decreases expression ISO Apaf1 (Mus musculus) 6480464 Copper analog results in decreased expression of APAF1 protein CTD PMID:21319953 copper atom multiple interactions ISO APAF1 (Homo sapiens) 6480464 [[Ditiocarb binds to Copper] which affects the localization of CYCS protein] promotes the reaction [[[CYCS protein binds to APAF1 protein binds to CASP9 protein] which results in increased metabolism of and results in increased activity of CASP9 protein] which results in increased activity of CASP3 protein] and [Chelating Agents binds to Copper] which results in increased expression of APAF1 mRNA CTD PMID:22951949 and PMID:30911355 copper(0) increases expression ISO Apaf1 (Mus musculus) 6480464 Copper analog results in increased expression of APAF1 protein CTD PMID:22000994 copper(0) increases expression EXP 6480464 Copper results in increased expression of APAF1 protein CTD PMID:30556269 copper(0) decreases expression ISO Apaf1 (Mus musculus) 6480464 Copper analog results in decreased expression of APAF1 protein CTD PMID:21319953 copper(0) multiple interactions ISO APAF1 (Homo sapiens) 6480464 [[Ditiocarb binds to Copper] which affects the localization of CYCS protein] promotes the reaction [[[CYCS protein binds to APAF1 protein binds to CASP9 protein] which results in increased metabolism of and results in increased activity of CASP9 protein] which results in increased activity of CASP3 protein] and [Chelating Agents binds to Copper] which results in increased expression of APAF1 mRNA CTD PMID:22951949 and PMID:30911355 curcumin increases expression ISO Apaf1 (Mus musculus) 6480464 Curcumin results in increased expression of APAF1 protein CTD PMID:17277231 curcumin multiple interactions EXP 6480464 Curcumin inhibits the reaction [Peroxynitrous Acid results in increased expression of APAF1 mRNA] CTD PMID:20869986 cycloheximide decreases expression ISO APAF1 (Homo sapiens) 6480464 Cycloheximide results in decreased expression of APAF1 mRNA CTD PMID:19684285 cycloheximide multiple interactions ISO APAF1 (Homo sapiens) 6480464 [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in decreased expression of APAF1 mRNA CTD PMID:19684285 cyclophosphamide decreases expression ISO APAF1 (Homo sapiens) 6480464 Cyclophosphamide results in decreased expression of APAF1 mRNA CTD PMID:29445054 cyfluthrin increases expression ISO APAF1 (Homo sapiens) 6480464 cyfluthrin results in increased expression of APAF1 mRNA CTD PMID:31330490 cylindrospermopsin decreases expression ISO APAF1 (Homo sapiens) 6480464 cylindrospermopsin results in decreased expression of APAF1 mRNA CTD PMID:23726867 cypermethrin increases expression ISO APAF1 (Homo sapiens) 6480464 cypermethrin results in increased expression of APAF1 mRNA and cypermethrin results in increased expression of APAF1 protein CTD PMID:27704156 and PMID:36063984 cypermethrin multiple interactions ISO Apaf1 (Mus musculus) 6480464 [Chlorpyrifos co-treated with cypermethrin] results in decreased expression of APAF1 protein more ... CTD PMID:34559034 cypermethrin decreases expression ISO Apaf1 (Mus musculus) 6480464 cypermethrin results in decreased expression of APAF1 mRNA and cypermethrin results in decreased expression of APAF1 protein CTD PMID:34559034 D-glucose multiple interactions ISO APAF1 (Homo sapiens) 6480464 [Glucose co-treated with Deferoxamine] results in increased expression of APAF1 mRNA and Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of APAF1 mRNA] CTD PMID:33962019 DDE increases expression EXP 6480464 Dichlorodiphenyl Dichloroethylene results in increased expression of APAF1 mRNA CTD PMID:25410718 decabromodiphenyl ether decreases expression ISO APAF1 (Homo sapiens) 6480464 decabromobiphenyl ether results in decreased expression of APAF1 protein CTD PMID:31675489 desferrioxamine B multiple interactions ISO APAF1 (Homo sapiens) 6480464 [Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of APAF1 mRNA more ... CTD PMID:33962019 and PMID:35690295 Di-n-octyl phthalate multiple interactions ISO Apaf1 (Mus musculus) 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of APAF1 mRNA CTD PMID:37364641 diarsenic trioxide increases expression ISO APAF1 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of APAF1 protein CTD PMID:25258189 diarsenic trioxide increases expression EXP 6480464 Arsenic Trioxide results in increased expression of APAF1 mRNA CTD PMID:19730151 diarsenic trioxide multiple interactions ISO APAF1 (Homo sapiens) 6480464 [Erlotinib Hydrochloride co-treated with Arsenic Trioxide] results in increased expression of APAF1 mRNA and [ruxolitinib co-treated with Arsenic Trioxide] results in increased expression of APAF1 mRNA CTD PMID:29274334 and PMID:30012499 diazinon affects expression EXP 6480464 Diazinon affects the expression of APAF1 mRNA CTD PMID:22546817 dibutyl phthalate increases expression ISO Apaf1 (Mus musculus) 6480464 Dibutyl Phthalate results in increased expression of APAF1 protein CTD PMID:34864091 dibutyl phthalate multiple interactions ISO Apaf1 (Mus musculus) 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of APAF1 mRNA CTD PMID:37364641 diclofenac affects expression ISO APAF1 (Homo sapiens) 6480464 Diclofenac affects the expression of APAF1 mRNA CTD PMID:24752500 Didecyldimethylammonium increases expression ISO APAF1 (Homo sapiens) 6480464 didecyldimethylammonium results in increased expression of APAF1 protein CTD PMID:32763356 dieldrin affects expression EXP 6480464 Dieldrin affects the expression of APAF1 mRNA CTD PMID:22546817 diepoxybutane increases expression ISO APAF1 (Homo sapiens) 6480464 diepoxybutane results in increased expression of APAF1 mRNA CTD PMID:29792945 diethyl maleate increases expression ISO APAF1 (Homo sapiens) 6480464 diethyl maleate results in increased expression of APAF1 mRNA CTD PMID:11875189 diethyl phthalate increases expression ISO Apaf1 (Mus musculus) 6480464 diethyl phthalate results in increased expression of APAF1 protein CTD PMID:37942807 diethyl phthalate multiple interactions ISO Apaf1 (Mus musculus) 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of APAF1 mRNA CTD PMID:37364641 diethyldithiocarbamic acid multiple interactions ISO APAF1 (Homo sapiens) 6480464 [[Ditiocarb binds to Copper] which affects the localization of CYCS protein] promotes the reaction [[[CYCS protein binds to APAF1 protein binds to CASP9 protein] which results in increased metabolism of and results in increased activity of CASP9 protein] which results in increased activity of CASP3 protein] CTD PMID:22951949 diethylstilbestrol decreases expression EXP 6480464 Diethylstilbestrol results in decreased expression of APAF1 mRNA CTD PMID:37077353 Diisodecyl phthalate multiple interactions ISO Apaf1 (Mus musculus) 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of APAF1 mRNA CTD PMID:37364641 diisononyl phthalate multiple interactions ISO Apaf1 (Mus musculus) 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of APAF1 mRNA CTD PMID:37364641 dioscin decreases expression ISO APAF1 (Homo sapiens) 6480464 dioscin results in decreased expression of APAF1 mRNA CTD PMID:33359023 diosgenin multiple interactions ISO APAF1 (Homo sapiens) 6480464 3-methyladenine inhibits the reaction [Diosgenin inhibits the reaction [alpha-Chlorohydrin results in increased expression of APAF1 protein]] and Diosgenin inhibits the reaction [alpha-Chlorohydrin results in increased expression of APAF1 protein] CTD PMID:35149085 dioxygen increases expression EXP 6480464 Oxygen deficiency results in increased expression of APAF1 protein CTD PMID:21468576 disulfiram increases expression ISO APAF1 (Homo sapiens) 6480464 Disulfiram results in increased expression of APAF1 mRNA CTD PMID:34182011 doxorubicin multiple interactions ISO APAF1 (Homo sapiens) 6480464 ginsenoside Rg1 promotes the reaction [Doxorubicin results in increased expression of APAF1 mRNA] more ... CTD PMID:15939500 more ... doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of APAF1 protein CTD PMID:22015447 and PMID:25169008 doxorubicin multiple interactions EXP 6480464 Propofol inhibits the reaction [Doxorubicin results in increased expression of APAF1 protein] CTD PMID:22015447 doxorubicin increases expression ISO APAF1 (Homo sapiens) 6480464 Doxorubicin results in increased expression of APAF1 mRNA and Doxorubicin results in increased expression of APAF1 protein CTD PMID:15939500 more ... ellagic acid decreases expression ISO APAF1 (Homo sapiens) 6480464 Ellagic Acid results in decreased expression of APAF1 mRNA CTD PMID:12002526 ellagic acid increases expression ISO APAF1 (Homo sapiens) 6480464 Ellagic Acid results in increased expression of APAF1 mRNA CTD PMID:35179410 endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of APAF1 mRNA CTD PMID:29391264 endosulfan increases expression ISO APAF1 (Homo sapiens) 6480464 Endosulfan results in increased expression of APAF1 protein CTD PMID:36513242 endosulfan decreases expression ISO APAF1 (Homo sapiens) 6480464 Endosulfan results in decreased expression of APAF1 mRNA CTD PMID:30090376 epichlorohydrin increases expression ISO APAF1 (Homo sapiens) 6480464 Epichlorohydrin results in increased expression of APAF1 mRNA CTD PMID:29792945 erlotinib hydrochloride multiple interactions ISO APAF1 (Homo sapiens) 6480464 [Erlotinib Hydrochloride co-treated with Arsenic Trioxide] results in increased expression of APAF1 mRNA CTD PMID:29274334 ethanol increases expression EXP 6480464 Ethanol results in increased expression of APAF1 mRNA CTD PMID:23273579 ethyl methanesulfonate increases expression ISO APAF1 (Homo sapiens) 6480464 Ethyl Methanesulfonate results in increased expression of APAF1 mRNA CTD PMID:23649840 etoposide increases expression ISO Apaf1 (Mus musculus) 6480464 Etoposide results in increased expression of APAF1 mRNA CTD PMID:25270620 eugenol multiple interactions ISO Apaf1 (Mus musculus) 6480464 Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of APAF1 protein] CTD PMID:20434464 flavone increases expression ISO APAF1 (Homo sapiens) 6480464 flavone results in increased expression of APAF1 protein CTD PMID:14750173 flavonoids increases expression EXP 6480464 Flavonoids results in increased expression of APAF1 mRNA CTD PMID:18035473 flutamide decreases expression EXP 6480464 Flutamide results in decreased expression of APAF1 mRNA CTD PMID:24793618 folic acid multiple interactions ISO Apaf1 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of APAF1 mRNA and [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of APAF1 gene CTD PMID:20938992 formaldehyde increases expression ISO APAF1 (Homo sapiens) 6480464 Formaldehyde results in increased expression of APAF1 mRNA CTD PMID:23649840 fructose multiple interactions ISO Apaf1 (Mus musculus) 6480464 [Fructose co-treated with Dietary Fats] results in increased expression of APAF1 mRNA and troxerutin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of APAF1 mRNA] CTD PMID:28916335 fumonisin B1 multiple interactions ISO Apaf1 (Mus musculus) 6480464 [fumonisin B1 co-treated with ochratoxin A] results in increased expression of APAF1 protein and fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of APAF1 mRNA] CTD PMID:36397609 furan increases expression EXP 6480464 furan results in increased expression of APAF1 mRNA CTD PMID:22079235 furosemide affects expression EXP 6480464 Furosemide affects the expression of APAF1 mRNA CTD PMID:17497460 genistein increases expression ISO APAF1 (Homo sapiens) 6480464 Genistein results in increased expression of APAF1 mRNA CTD PMID:15256057 genistein increases expression ISO Apaf1 (Mus musculus) 6480464 Genistein results in increased expression of APAF1 mRNA CTD PMID:24967385 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of APAF1 mRNA CTD PMID:22061828 gingerol increases expression ISO APAF1 (Homo sapiens) 6480464 gingerol results in increased expression of APAF1 mRNA and gingerol results in increased expression of APAF1 protein CTD PMID:19481070 ginsenoside Rg1 multiple interactions ISO APAF1 (Homo sapiens) 6480464 ginsenoside Rg1 promotes the reaction [Doxorubicin results in increased expression of APAF1 mRNA] CTD PMID:34783124 glucaric acid multiple interactions ISO Apaf1 (Mus musculus) 6480464 [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9 more ... CTD PMID:25478867 glucose multiple interactions ISO APAF1 (Homo sapiens) 6480464 [Glucose co-treated with Deferoxamine] results in increased expression of APAF1 mRNA and Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of APAF1 mRNA] CTD PMID:33962019 glyphosate affects methylation EXP 6480464 Glyphosate affects the methylation of APAF1 gene CTD PMID:35440735 glyphosate increases expression ISO APAF1 (Homo sapiens) 6480464 Glyphosate results in increased expression of APAF1 mRNA CTD PMID:31874349 glyphosate decreases expression ISO APAF1 (Homo sapiens) 6480464 Glyphosate results in decreased expression of APAF1 mRNA and Glyphosate results in decreased expression of APAF1 protein CTD PMID:24073338 and PMID:31295307 gold atom multiple interactions ISO APAF1 (Homo sapiens) 6480464 [Polyethyleneimine binds to Gold] which results in decreased expression of APAF1 mRNA and [Quercetin analog co-treated with Gold analog] results in increased expression of APAF1 protein CTD PMID:27470402 and PMID:28433809 gold atom decreases expression ISO APAF1 (Homo sapiens) 6480464 Gold analog results in decreased expression of APAF1 mRNA CTD PMID:36057382 gold(0) multiple interactions ISO APAF1 (Homo sapiens) 6480464 [Polyethyleneimine binds to Gold] which results in decreased expression of APAF1 mRNA and [Quercetin analog co-treated with Gold analog] results in increased expression of APAF1 protein CTD PMID:27470402 and PMID:28433809 gold(0) decreases expression ISO APAF1 (Homo sapiens) 6480464 Gold analog results in decreased expression of APAF1 mRNA CTD PMID:36057382 hydroxyurea increases expression ISO Apaf1 (Mus musculus) 6480464 Hydroxyurea results in increased expression of APAF1 mRNA CTD PMID:27208086 indole-3-methanol increases expression ISO Apaf1 (Mus musculus) 6480464 indole-3-carbinol results in increased expression of APAF1 protein CTD PMID:29775573 isoflurane decreases expression EXP 6480464 Isoflurane results in decreased expression of APAF1 mRNA CTD PMID:16978161 isoprenaline increases expression ISO APAF1 (Homo sapiens) 6480464 Isoproterenol results in increased expression of APAF1 mRNA CTD PMID:24286936 ivermectin decreases expression ISO APAF1 (Homo sapiens) 6480464 Ivermectin results in decreased expression of APAF1 protein CTD PMID:32959892 kainic acid increases expression ISO Apaf1 (Mus musculus) 6480464 Kainic Acid results in increased expression of APAF1 mRNA CTD PMID:17997037 ketoconazole decreases expression EXP 6480464 Ketoconazole results in decreased expression of APAF1 mRNA CTD PMID:37077353 L-methionine multiple interactions ISO Apaf1 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of APAF1 mRNA and [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of APAF1 gene CTD PMID:20938992 lead diacetate increases expression ISO Apaf1 (Mus musculus) 6480464 lead acetate results in increased expression of APAF1 mRNA CTD PMID:20542052 lead diacetate multiple interactions EXP 6480464 sinapinic acid inhibits the reaction [lead acetate results in increased expression of APAF1 mRNA] CTD PMID:37471654 lead diacetate increases expression EXP 6480464 lead acetate results in increased expression of APAF1 mRNA CTD PMID:37471654 lead nitrate multiple interactions ISO Apaf1 (Mus musculus) 6480464 mangiferin inhibits the reaction [lead nitrate results in decreased expression of APAF1 protein] CTD PMID:23451106 lead nitrate decreases expression ISO Apaf1 (Mus musculus) 6480464 lead nitrate results in decreased expression of APAF1 protein CTD PMID:23451106 leptomycin B multiple interactions ISO APAF1 (Homo sapiens) 6480464 [leptomycin B co-treated with TP53 gene mutant form] results in increased expression of APAF1 mRNA CTD PMID:20803015 linuron increases expression EXP 6480464 Linuron results in increased expression of APAF1 mRNA CTD PMID:28705778 lipopolysaccharide decreases expression ISO Apaf1 (Mus musculus) 6480464 Lipopolysaccharides results in decreased expression of APAF1 mRNA and Lipopolysaccharides results in decreased expression of APAF1 protein CTD PMID:33865415 lipopolysaccharide multiple interactions ISO Apaf1 (Mus musculus) 6480464 [Lipopolysaccharides co-treated with 2 more ... CTD PMID:33865415 mangiferin multiple interactions ISO Apaf1 (Mus musculus) 6480464 mangiferin inhibits the reaction [lead nitrate results in decreased expression of APAF1 protein] CTD PMID:23451106 MeIQx increases expression ISO APAF1 (Homo sapiens) 6480464 2-amino-3 more ... CTD PMID:20816883 melatonin multiple interactions ISO APAF1 (Homo sapiens) 6480464 Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of APAF1 mRNA] CTD PMID:33962019 melittin multiple interactions EXP 6480464 Melitten inhibits the reaction [[IL6 protein co-treated with IL6R protein] results in increased expression of APAF1 protein] CTD PMID:21354845 melittin multiple interactions ISO Apaf1 (Mus musculus) 6480464 Melitten affects the reaction [TGFB1 protein affects the localization of APAF1 protein] CTD PMID:21871910 metformin multiple interactions ISO APAF1 (Homo sapiens) 6480464 [Paclitaxel co-treated with Metformin] results in increased expression of APAF1 mRNA CTD PMID:29309887 methotrexate increases expression ISO APAF1 (Homo sapiens) 6480464 Methotrexate results in increased expression of APAF1 mRNA CTD PMID:21678067 and PMID:24449571 methyl methanesulfonate affects response to substance ISO Apaf1 (Mus musculus) 6480464 APAF1 protein affects the susceptibility to Methyl Methanesulfonate CTD PMID:16019050 methyl methanesulfonate increases expression ISO APAF1 (Homo sapiens) 6480464 Methyl Methanesulfonate results in increased expression of APAF1 mRNA CTD PMID:23649840 methylisothiazolinone increases expression ISO APAF1 (Homo sapiens) 6480464 2-methyl-4-isothiazolin-3-one results in increased expression of APAF1 protein CTD PMID:29110394 and PMID:31629900 methylmercury chloride increases expression ISO APAF1 (Homo sapiens) 6480464 methylmercuric chloride results in increased expression of APAF1 mRNA CTD PMID:28001369 mitomycin C increases expression ISO Apaf1 (Mus musculus) 6480464 Mitomycin results in increased expression of APAF1 mRNA CTD PMID:25270620 morin increases expression ISO APAF1 (Homo sapiens) 6480464 morin results in increased expression of APAF1 mRNA CTD PMID:28689916 Muraglitazar decreases expression EXP 6480464 muraglitazar results in decreased expression of APAF1 mRNA CTD PMID:21515302 N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Cholesterol analog results in increased expression of APAF1 mRNA] and Acetylcysteine inhibits the reaction [tert-Butylhydroperoxide results in increased expression of APAF1 protein] CTD PMID:15877105 and PMID:19477266 N-acetyl-L-cysteine multiple interactions ISO APAF1 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [Methylmercury Compounds results in increased expression of APAF1 protein] CTD PMID:35396826 N-methyl-N'-nitro-N-nitrosoguanidine affects response to substance ISO Apaf1 (Mus musculus) 6480464 APAF1 protein affects the susceptibility to Methylnitronitrosoguanidine CTD PMID:16019050 N-methyl-N'-nitro-N-nitrosoguanidine decreases expression ISO Apaf1 (Mus musculus) 6480464 Methylnitronitrosoguanidine results in decreased expression of APAF1 protein CTD PMID:20434464 N-methyl-N'-nitro-N-nitrosoguanidine multiple interactions ISO Apaf1 (Mus musculus) 6480464 Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of APAF1 protein] CTD PMID:20434464 N-methyl-N-nitrosourea increases expression ISO Apaf1 (Mus musculus) 6480464 Methylnitrosourea results in increased expression of APAF1 mRNA CTD PMID:25270620 N-nitrosodiethylamine multiple interactions ISO Apaf1 (Mus musculus) 6480464 AHR protein affects the reaction [Diethylnitrosamine affects the expression of APAF1 mRNA] and AHR protein inhibits the reaction [Diethylnitrosamine results in decreased expression of APAF1 mRNA] CTD PMID:19996281 N-nitrosodiethylamine multiple interactions EXP 6480464 [3 more ... CTD PMID:27048571 N-nitrosodiethylamine affects expression ISO Apaf1 (Mus musculus) 6480464 Diethylnitrosamine affects the expression of APAF1 mRNA CTD PMID:19996281 and PMID:21159647 N-nitrosodimethylamine increases expression EXP 6480464 Dimethylnitrosamine results in increased expression of APAF1 mRNA CTD PMID:25380136 neomycin increases expression ISO Apaf1 (Mus musculus) 6480464 Neomycin results in increased expression of APAF1 mRNA CTD PMID:29292089 neomycin multiple interactions ISO Apaf1 (Mus musculus) 6480464 peoniflorin inhibits the reaction [Neomycin results in increased expression of APAF1 mRNA] CTD PMID:29292089 nickel atom decreases expression ISO APAF1 (Homo sapiens) 6480464 Nickel results in decreased expression of APAF1 mRNA CTD PMID:23195993 nicotinamide multiple interactions ISO Apaf1 (Mus musculus) 6480464 [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9 more ... CTD PMID:25478867 ochratoxin A increases expression EXP 6480464 ochratoxin A results in increased expression of APAF1 mRNA CTD PMID:19562491 ochratoxin A increases expression ISO Apaf1 (Mus musculus) 6480464 ochratoxin A results in increased expression of APAF1 mRNA CTD PMID:36397609 ochratoxin A multiple interactions ISO Apaf1 (Mus musculus) 6480464 [fumonisin B1 co-treated with ochratoxin A] results in increased expression of APAF1 protein and fumonisin B1 promotes the reaction [ochratoxin A results in increased expression of APAF1 mRNA] CTD PMID:36397609 ochratoxin A decreases expression ISO APAF1 (Homo sapiens) 6480464 ochratoxin A results in decreased expression of APAF1 mRNA CTD PMID:17316727 okadaic acid increases expression ISO APAF1 (Homo sapiens) 6480464 Okadaic Acid results in increased expression of APAF1 mRNA CTD PMID:31926150 ouabain increases expression ISO APAF1 (Homo sapiens) 6480464 Ouabain results in increased expression of APAF1 protein CTD PMID:31436044 ozone multiple interactions ISO Apaf1 (Mus musculus) 6480464 [Vehicle Emissions results in increased abundance of Ozone] which results in increased expression of APAF1 protein CTD PMID:21355040 p-menthan-3-ol increases expression ISO APAF1 (Homo sapiens) 6480464 Menthol results in increased expression of APAF1 mRNA CTD PMID:26760959 paclitaxel increases expression ISO APAF1 (Homo sapiens) 6480464 Paclitaxel results in increased expression of APAF1 protein CTD PMID:14749477 paclitaxel multiple interactions ISO APAF1 (Homo sapiens) 6480464 [Paclitaxel co-treated with Metformin] results in increased expression of APAF1 mRNA CTD PMID:29309887 paclitaxel multiple interactions ISO Apaf1 (Mus musculus) 6480464 APAF1 protein affects the reaction [Paclitaxel results in increased activity of and results in increased cleavage of CASP3 protein] CTD PMID:17652622 paeoniflorin multiple interactions ISO Apaf1 (Mus musculus) 6480464 peoniflorin inhibits the reaction [Neomycin results in increased expression of APAF1 mRNA] CTD PMID:29292089 paracetamol affects expression ISO Apaf1 (Mus musculus) 6480464 Acetaminophen affects the expression of APAF1 mRNA CTD PMID:17562736 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of APAF1 mRNA CTD PMID:33387578 paracetamol increases expression ISO APAF1 (Homo sapiens) 6480464 Acetaminophen results in increased expression of APAF1 mRNA CTD PMID:22230336 paracetamol increases expression ISO Apaf1 (Mus musculus) 6480464 Acetaminophen results in increased expression of APAF1 mRNA CTD PMID:11752693 paraquat decreases expression ISO APAF1 (Homo sapiens) 6480464 Paraquat results in decreased expression of APAF1 mRNA CTD PMID:17064354 paraquat affects splicing ISO Apaf1 (Mus musculus) 6480464 Paraquat affects the splicing of APAF1 exon CTD PMID:27111068 paraquat affects splicing ISO APAF1 (Homo sapiens) 6480464 Paraquat affects the splicing of APAF1 mRNA CTD PMID:23613995 paraquat increases expression ISO APAF1 (Homo sapiens) 6480464 Paraquat results in increased expression of APAF1 mRNA alternative form CTD PMID:17064354 pentobarbital decreases expression EXP 6480464 Pentobarbital results in decreased expression of APAF1 mRNA CTD PMID:16978161 perfluorononanoic acid decreases expression ISO APAF1 (Homo sapiens) 6480464 perfluoro-n-nonanoic acid results in decreased expression of APAF1 mRNA CTD PMID:32588087 peroxynitrous acid multiple interactions EXP 6480464 Curcumin inhibits the reaction [Peroxynitrous Acid results in increased expression of APAF1 mRNA] CTD PMID:20869986 peroxynitrous acid increases expression EXP 6480464 Peroxynitrous Acid results in increased expression of APAF1 mRNA CTD PMID:20869986 phenethyl isothiocyanate increases expression ISO APAF1 (Homo sapiens) 6480464 phenethyl isothiocyanate results in increased expression of APAF1 protein CTD PMID:16054126 phenobarbital affects expression ISO Apaf1 (Mus musculus) 6480464 Phenobarbital affects the expression of APAF1 mRNA CTD PMID:23091169 phenobarbital multiple interactions EXP 6480464 [3 more ... CTD PMID:27048571 phenobarbital increases expression EXP 6480464 Phenobarbital results in increased expression of APAF1 mRNA CTD PMID:23273579 PhIP decreases expression ISO APAF1 (Homo sapiens) 6480464 2-amino-1-methyl-6-phenylimidazo(4 and 5-b)pyridine results in decreased expression of APAF1 mRNA CTD PMID:20816883 phorbol 13-acetate 12-myristate affects expression ISO APAF1 (Homo sapiens) 6480464 Tetradecanoylphorbol Acetate affects the expression of APAF1 protein CTD PMID:11139146 pifithrin-? increases expression ISO APAF1 (Homo sapiens) 6480464 pifithrin results in increased expression of APAF1 protein CTD PMID:28483490 pirinixic acid decreases expression ISO Apaf1 (Mus musculus) 6480464 pirinixic acid results in decreased expression of APAF1 mRNA CTD PMID:17426115 propofol decreases expression EXP 6480464 Propofol results in decreased expression of APAF1 protein CTD PMID:21468576 propofol multiple interactions EXP 6480464 Propofol inhibits the reaction [Doxorubicin results in increased expression of APAF1 protein] CTD PMID:22015447 propylparaben increases expression ISO APAF1 (Homo sapiens) 6480464 propylparaben results in increased expression of APAF1 mRNA CTD PMID:24481588 pyrethrins decreases expression ISO APAF1 (Homo sapiens) 6480464 Pyrethrins results in decreased expression of APAF1 mRNA CTD PMID:35321623 quercetin decreases expression ISO APAF1 (Homo sapiens) 6480464 Quercetin results in decreased expression of APAF1 mRNA CTD PMID:15309432 quercetin multiple interactions ISO APAF1 (Homo sapiens) 6480464 [Quercetin analog co-treated with Gold analog] results in increased expression of APAF1 protein CTD PMID:27470402 quercetin increases expression ISO APAF1 (Homo sapiens) 6480464 Quercetin results in increased expression of APAF1 mRNA and Quercetin results in increased expression of APAF1 protein CTD PMID:14750173 more ... resveratrol decreases expression ISO APAF1 (Homo sapiens) 6480464 resveratrol results in decreased expression of APAF1 mRNA and resveratrol results in decreased expression of APAF1 protein CTD PMID:12002526 and PMID:14749477 resveratrol increases expression ISO APAF1 (Homo sapiens) 6480464 resveratrol results in increased expression of APAF1 mRNA CTD PMID:12569576 rotenone increases expression ISO APAF1 (Homo sapiens) 6480464 Rotenone results in increased expression of APAF1 mRNA alternative form CTD PMID:17064354 ruxolitinib multiple interactions ISO APAF1 (Homo sapiens) 6480464 [ruxolitinib co-treated with Arsenic Trioxide] results in increased expression of APAF1 mRNA CTD PMID:30012499 S-(1,2-dichlorovinyl)-L-cysteine increases expression ISO APAF1 (Homo sapiens) 6480464 S-(1 and 2-dichlorovinyl)cysteine results in increased expression of APAF1 protein CTD PMID:15967204 safrole increases expression ISO APAF1 (Homo sapiens) 6480464 Safrole results in increased expression of APAF1 protein CTD PMID:21591240 Se-methyl-L-selenocysteine increases expression ISO APAF1 (Homo sapiens) 6480464 selenomethylselenocysteine metabolite results in increased expression of APAF1 mRNA CTD PMID:25321483 Se-methylselenocysteine increases expression ISO APAF1 (Homo sapiens) 6480464 selenomethylselenocysteine metabolite results in increased expression of APAF1 mRNA CTD PMID:25321483 sinapic acid multiple interactions EXP 6480464 sinapinic acid inhibits the reaction [lead acetate results in increased expression of APAF1 mRNA] CTD PMID:37471654 sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of APAF1 protein CTD PMID:20830294 sodium arsenite increases expression ISO Apaf1 (Mus musculus) 6480464 sodium arsenite results in increased expression of APAF1 protein CTD PMID:29854073 sodium arsenite multiple interactions ISO Apaf1 (Mus musculus) 6480464 salvin inhibits the reaction [sodium arsenite results in increased expression of APAF1 protein] CTD PMID:29854073 sodium arsenite multiple interactions EXP 6480464 Taurine inhibits the reaction [sodium arsenite results in increased expression of APAF1 protein] CTD PMID:20830294 sodium dichromate multiple interactions ISO Apaf1 (Mus musculus) 6480464 [Benzo(a)pyrene co-treated with sodium bichromate] results in increased expression of APAF1 mRNA CTD PMID:22613061 sodium fluoride increases expression ISO Apaf1 (Mus musculus) 6480464 Sodium Fluoride results in increased expression of APAF1 mRNA CTD PMID:30225638 tanespimycin multiple interactions ISO APAF1 (Homo sapiens) 6480464 Scorpion Venoms results in increased susceptibility to [tanespimycin results in increased expression of APAF1 protein] CTD PMID:19913524 tanespimycin increases expression ISO APAF1 (Homo sapiens) 6480464 tanespimycin results in increased expression of APAF1 protein CTD PMID:19913524 taurine multiple interactions EXP 6480464 Taurine inhibits the reaction [Alloxan results in increased expression of APAF1 protein] and Taurine inhibits the reaction [sodium arsenite results in increased expression of APAF1 protein] CTD PMID:20830294 and PMID:23092809 tauroursodeoxycholic acid affects expression EXP 6480464 ursodoxicoltaurine affects the expression of APAF1 mRNA and ursodoxicoltaurine affects the expression of APAF1 protein CTD PMID:15885361 tauroursodeoxycholic acid decreases expression EXP 6480464 ursodoxicoltaurine results in decreased expression of APAF1 mRNA CTD PMID:15885361 tert-butyl hydroperoxide increases expression ISO APAF1 (Homo sapiens) 6480464 tert-Butylhydroperoxide results in increased expression of APAF1 protein CTD PMID:17419000 tert-butyl hydroperoxide multiple interactions ISO APAF1 (Homo sapiens) 6480464 [Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of APAF1 mRNA more ... CTD PMID:35690295 tert-butyl hydroperoxide increases expression EXP 6480464 tert-Butylhydroperoxide results in increased expression of APAF1 protein CTD PMID:15877105 tert-butyl hydroperoxide multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [tert-Butylhydroperoxide results in increased expression of APAF1 protein] CTD PMID:15877105 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of APAF1 mRNA CTD PMID:34492290 topotecan multiple interactions ISO Apaf1 (Mus musculus) 6480464 APAF1 promotes the reaction [Topotecan results in increased cleavage of BID protein] more ... CTD PMID:19812371 Tributyltin oxide increases expression ISO Apaf1 (Mus musculus) 6480464 bis(tri-n-butyltin)oxide results in increased expression of APAF1 mRNA CTD PMID:22434021 trichloroethene increases methylation EXP 6480464 Trichloroethylene results in increased methylation of APAF1 gene CTD PMID:27618143 trichostatin A multiple interactions ISO APAF1 (Homo sapiens) 6480464 [trichostatin A results in increased activity of APAF1 protein] which results in increased susceptibility to Cisplatin CTD PMID:20925046 trichostatin A increases activity ISO APAF1 (Homo sapiens) 6480464 trichostatin A results in increased activity of APAF1 protein CTD PMID:20925046 Triptolide increases expression ISO Apaf1 (Mus musculus) 6480464 triptolide results in increased expression of APAF1 protein CTD PMID:25169008 and PMID:26990902 Triptolide multiple interactions EXP 6480464 NFE2L2 protein inhibits the reaction [triptolide results in increased expression of APAF1 protein] CTD PMID:25169008 Triptolide increases expression EXP 6480464 triptolide results in increased expression of APAF1 protein CTD PMID:25169008 troglitazone decreases expression EXP 6480464 troglitazone results in decreased expression of APAF1 mRNA CTD PMID:21515302 urethane increases expression ISO APAF1 (Homo sapiens) 6480464 Urethane results in increased expression of APAF1 mRNA CTD PMID:28818685 ursodeoxycholic acid decreases expression EXP 6480464 Ursodeoxycholic Acid results in decreased expression of APAF1 mRNA and Ursodeoxycholic Acid results in decreased expression of APAF1 protein CTD PMID:15885361 valproic acid increases expression ISO APAF1 (Homo sapiens) 6480464 Valproic Acid results in increased expression of APAF1 mRNA CTD PMID:24935251 vemurafenib multiple interactions ISO APAF1 (Homo sapiens) 6480464 [(+)-JQ1 compound co-treated with vemurafenib] results in decreased expression of APAF1 mRNA CTD PMID:27169980 vinclozolin decreases expression EXP 6480464 vinclozolin results in decreased expression of APAF1 mRNA CTD PMID:23869203 WIN 55212-2 decreases expression ISO APAF1 (Homo sapiens) 6480464 (3R)-((2 more ... CTD PMID:30776504 zearalenone increases expression ISO Apaf1 (Mus musculus) 6480464 Zearalenone results in increased expression of APAF1 mRNA CTD PMID:34537261 zebularine affects expression ISO APAF1 (Homo sapiens) 6480464 pyrimidin-2-one beta-ribofuranoside affects the expression of APAF1 mRNA CTD PMID:17133271 zinc oxide multiple interactions ISO Apaf1 (Mus musculus) 6480464 Zinc Oxide affects the splicing of and results in increased expression of APAF1 mRNA CTD PMID:30500950 zoledronic acid increases expression ISO APAF1 (Homo sapiens) 6480464 zoledronic acid results in increased expression of APAF1 mRNA CTD PMID:28871336 zoledronic acid increases expression ISO Apaf1 (Mus musculus) 6480464 zoledronic acid results in increased expression of APAF1 mRNA CTD PMID:28871336
