Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Dcbld2 | Rat | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of DCBLD2 mRNA] | CTD | PMID:31150632 | Dcbld2 | Rat | 1,1-dichloroethene | decreases expression | ISO | Dcbld2 (Mus musculus) | 6480464 | vinylidene chloride results in decreased expression of DCBLD2 mRNA | CTD | PMID:26682919 | Dcbld2 | Rat | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of DCBLD2 mRNA | CTD | PMID:29097150 | Dcbld2 | Rat | 17beta-estradiol | multiple interactions | ISO | DCBLD2 (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in increased expression of DCBLD2 mRNA | CTD | PMID:30165855 | Dcbld2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Dcbld2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of DCBLD2 mRNA | CTD | PMID:19770486 | Dcbld2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of DCBLD2 mRNA | CTD | PMID:32109520 | Dcbld2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Dcbld2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of DCBLD2 mRNA | CTD | PMID:21570461 | Dcbld2 | Rat | 2-butoxyethanol | increases expression | ISO | Dcbld2 (Mus musculus) | 6480464 | n-butoxyethanol results in increased expression of DCBLD2 mRNA | CTD | PMID:19812364 | Dcbld2 | Rat | 3,3',4,4',5-pentachlorobiphenyl | decreases expression | EXP | | 6480464 | 3 more ... | CTD | PMID:23196670 | Dcbld2 | Rat | 4,4'-sulfonyldiphenol | decreases methylation | ISO | Dcbld2 (Mus musculus) | 6480464 | bisphenol S results in decreased methylation of DCBLD2 exon | CTD | PMID:33297965 | Dcbld2 | Rat | 4-hydroxyphenyl retinamide | decreases expression | ISO | Dcbld2 (Mus musculus) | 6480464 | Fenretinide results in decreased expression of DCBLD2 mRNA | CTD | PMID:28973697 | Dcbld2 | Rat | 5-aza-2'-deoxycytidine | multiple interactions | ISO | DCBLD2 (Homo sapiens) | 6480464 | [[Decitabine co-treated with trichostatin A] affects the methylation of DCBLD2 promoter] which affects the expression of DCBLD2 mRNA more ... | CTD | PMID:18314483 | Dcbld2 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of DCBLD2 mRNA | CTD | PMID:24780913 | Dcbld2 | Rat | 8-Br-cAMP | increases expression | ISO | DCBLD2 (Homo sapiens) | 6480464 | 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of DCBLD2 mRNA | CTD | PMID:22079614 | Dcbld2 | Rat | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of DCBLD2 mRNA | CTD | PMID:31881176 | Dcbld2 | Rat | aflatoxin B1 | increases expression | ISO | DCBLD2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of DCBLD2 mRNA | CTD | PMID:21641981 and PMID:22100608 | Dcbld2 | Rat | aflatoxin M1 | decreases expression | ISO | DCBLD2 (Homo sapiens) | 6480464 | Aflatoxin M1 results in decreased expression of DCBLD2 mRNA | CTD | PMID:30928695 | Dcbld2 | Rat | all-trans-retinoic acid | decreases expression | ISO | DCBLD2 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of DCBLD2 mRNA | CTD | PMID:33167477 | Dcbld2 | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of DCBLD2 mRNA | CTD | PMID:16483693 | Dcbld2 | Rat | antirheumatic drug | increases expression | ISO | DCBLD2 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of DCBLD2 mRNA | CTD | PMID:24449571 | Dcbld2 | Rat | aristolochic acid A | decreases expression | ISO | DCBLD2 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of DCBLD2 mRNA | CTD | PMID:33212167 | Dcbld2 | Rat | arsane | multiple interactions | ISO | DCBLD2 (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of DCBLD2 mRNA | CTD | PMID:32525701 | Dcbld2 | Rat | arsenic atom | multiple interactions | ISO | DCBLD2 (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of DCBLD2 mRNA | CTD | PMID:32525701 | Dcbld2 | Rat | arsenous acid | increases expression | ISO | DCBLD2 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of DCBLD2 mRNA | CTD | PMID:26705709 | Dcbld2 | Rat | avobenzone | increases expression | ISO | DCBLD2 (Homo sapiens) | 6480464 | avobenzone results in increased expression of DCBLD2 mRNA | CTD | PMID:31016361 | Dcbld2 | Rat | benzo[a]pyrene | increases expression | ISO | DCBLD2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of DCBLD2 mRNA | CTD | PMID:21871943 | Dcbld2 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of DCBLD2 mRNA | CTD | PMID:29097150 | Dcbld2 | Rat | bisphenol A | multiple interactions | ISO | DCBLD2 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of DCBLD2 gene | CTD | PMID:31601247 | Dcbld2 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of DCBLD2 mRNA | CTD | PMID:30816183 | Dcbld2 | Rat | bisphenol A | affects response to substance | ISO | Dcbld2 (Mus musculus) | 6480464 | DCBLD2 mRNA alternative form affects the susceptibility to bisphenol A | CTD | PMID:31020848 | Dcbld2 | Rat | bisphenol A | increases expression | ISO | Dcbld2 (Mus musculus) | 6480464 | bisphenol A results in increased expression of DCBLD2 mRNA alternative form | CTD | PMID:31020848 | Dcbld2 | Rat | butan-1-ol | multiple interactions | ISO | DCBLD2 (Homo sapiens) | 6480464 | [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of DCBLD2 mRNA | CTD | PMID:29432896 | Dcbld2 | Rat | cadmium atom | multiple interactions | ISO | DCBLD2 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of DCBLD2 mRNA | CTD | PMID:35301059 | Dcbld2 | Rat | cadmium dichloride | affects expression | EXP | | 6480464 | Cadmium Chloride affects the expression of DCBLD2 mRNA | CTD | PMID:22110744 | Dcbld2 | Rat | cadmium dichloride | multiple interactions | ISO | DCBLD2 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of DCBLD2 mRNA | CTD | PMID:35301059 | Dcbld2 | Rat | caffeine | affects phosphorylation | ISO | DCBLD2 (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of DCBLD2 protein | CTD | PMID:35688186 | Dcbld2 | Rat | calcitriol | increases expression | ISO | DCBLD2 (Homo sapiens) | 6480464 | Calcitriol results in increased expression of DCBLD2 mRNA | CTD | PMID:16002434 | Dcbld2 | Rat | chloropicrin | decreases expression | ISO | DCBLD2 (Homo sapiens) | 6480464 | chloropicrin results in decreased expression of DCBLD2 mRNA | CTD | PMID:26352163 | Dcbld2 | Rat | cisplatin | decreases expression | ISO | DCBLD2 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of DCBLD2 mRNA | CTD | PMID:19561079 | Dcbld2 | Rat | cisplatin | multiple interactions | ISO | DCBLD2 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of DCBLD2 mRNA | CTD | PMID:27392435 | Dcbld2 | Rat | cobalt dichloride | decreases expression | ISO | DCBLD2 (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of DCBLD2 mRNA | CTD | PMID:19320972 | Dcbld2 | Rat | copper(II) sulfate | increases expression | ISO | DCBLD2 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of DCBLD2 mRNA | CTD | PMID:19549813 | Dcbld2 | Rat | coumarin | increases phosphorylation | ISO | DCBLD2 (Homo sapiens) | 6480464 | coumarin results in increased phosphorylation of DCBLD2 protein | CTD | PMID:35688186 | Dcbld2 | Rat | cyclosporin A | increases expression | ISO | Dcbld2 (Mus musculus) | 6480464 | Cyclosporine results in increased expression of DCBLD2 mRNA | CTD | PMID:19770486 | Dcbld2 | Rat | cyclosporin A | increases expression | ISO | DCBLD2 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of DCBLD2 mRNA | CTD | PMID:25562108 | Dcbld2 | Rat | dexamethasone | increases expression | ISO | Dcbld2 (Mus musculus) | 6480464 | Dexamethasone results in increased expression of DCBLD2 mRNA | CTD | PMID:22733784 | Dcbld2 | Rat | diarsenic trioxide | increases expression | ISO | DCBLD2 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of DCBLD2 mRNA | CTD | PMID:26705709 | Dcbld2 | Rat | dibutyl phthalate | increases expression | ISO | Dcbld2 (Mus musculus) | 6480464 | Dibutyl Phthalate results in increased expression of DCBLD2 mRNA | CTD | PMID:21266533 | Dcbld2 | Rat | dorsomorphin | multiple interactions | ISO | DCBLD2 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of DCBLD2 mRNA | CTD | PMID:27188386 | Dcbld2 | Rat | doxorubicin | decreases expression | ISO | DCBLD2 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of DCBLD2 mRNA | CTD | PMID:29803840 | Dcbld2 | Rat | ethanol | multiple interactions | ISO | DCBLD2 (Homo sapiens) | 6480464 | [[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of DCBLD2 mRNA | CTD | PMID:29432896 | Dcbld2 | Rat | FR900359 | decreases phosphorylation | ISO | DCBLD2 (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of DCBLD2 protein | CTD | PMID:37730182 | Dcbld2 | Rat | fulvestrant | multiple interactions | ISO | DCBLD2 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of DCBLD2 gene | CTD | PMID:31601247 | Dcbld2 | Rat | graphite | affects expression | EXP | | 6480464 | Graphite affects the expression of DCBLD2 mRNA | CTD | PMID:29933104 | Dcbld2 | Rat | isobutanol | multiple interactions | ISO | DCBLD2 (Homo sapiens) | 6480464 | [[Gasoline co-treated with isobutyl alcohol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of DCBLD2 mRNA | CTD | PMID:29432896 | Dcbld2 | Rat | ivermectin | decreases expression | ISO | DCBLD2 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of DCBLD2 protein | CTD | PMID:32959892 | Dcbld2 | Rat | lipopolysaccharide | increases expression | ISO | Dcbld2 (Mus musculus) | 6480464 | Lipopolysaccharides results in increased expression of DCBLD2 mRNA | CTD | PMID:25890327 | Dcbld2 | Rat | lipopolysaccharide | multiple interactions | ISO | DCBLD2 (Homo sapiens) | 6480464 | [NAT10 protein affects the susceptibility to Lipopolysaccharides] which affects the expression of DCBLD2 mRNA | CTD | PMID:35877022 | Dcbld2 | Rat | methylparaben | decreases expression | ISO | DCBLD2 (Homo sapiens) | 6480464 | methylparaben results in decreased expression of DCBLD2 mRNA | CTD | PMID:31745603 | Dcbld2 | Rat | N-ethyl-N-nitrosourea | increases mutagenesis | EXP | | 6480464 | Ethylnitrosourea results in increased mutagenesis of DCBLD2 gene | CTD | PMID:16495775 | Dcbld2 | Rat | N-methyl-4-phenylpyridinium | decreases expression | ISO | DCBLD2 (Homo sapiens) | 6480464 | 1-Methyl-4-phenylpyridinium results in decreased expression of DCBLD2 mRNA | CTD | PMID:24810058 | Dcbld2 | Rat | nickel atom | decreases expression | ISO | DCBLD2 (Homo sapiens) | 6480464 | Nickel results in decreased expression of DCBLD2 mRNA | CTD | PMID:25583101 | Dcbld2 | Rat | nickel sulfate | decreases expression | ISO | DCBLD2 (Homo sapiens) | 6480464 | nickel sulfate results in decreased expression of DCBLD2 mRNA | CTD | PMID:22714537 | Dcbld2 | Rat | ozone | multiple interactions | ISO | Dcbld2 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of DCBLD2 mRNA and [Air Pollutants results in increased abundance of Ozone] which results in increased expression of DCBLD2 mRNA | CTD | PMID:34911549 | Dcbld2 | Rat | paracetamol | increases expression | ISO | DCBLD2 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of DCBLD2 mRNA | CTD | PMID:22230336 and PMID:29067470 | Dcbld2 | Rat | paracetamol | affects expression | ISO | DCBLD2 (Homo sapiens) | 6480464 | Acetaminophen affects the expression of DCBLD2 mRNA | CTD | PMID:25458485 | Dcbld2 | Rat | PD 0325901 | decreases expression | ISO | DCBLD2 (Homo sapiens) | 6480464 | mirdametinib results in decreased expression of DCBLD2 mRNA | CTD | PMID:25119042 | Dcbld2 | Rat | pirinixic acid | increases expression | ISO | Dcbld2 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of DCBLD2 mRNA | CTD | PMID:18301758 | Dcbld2 | Rat | progesterone | decreases expression | ISO | DCBLD2 (Homo sapiens) | 6480464 | Progesterone results in decreased expression of DCBLD2 mRNA | CTD | PMID:21795739 | Dcbld2 | Rat | propanal | increases expression | ISO | DCBLD2 (Homo sapiens) | 6480464 | propionaldehyde results in increased expression of DCBLD2 mRNA | CTD | PMID:26079696 | Dcbld2 | Rat | pyrogallol | decreases expression | ISO | Dcbld2 (Mus musculus) | 6480464 | Pyrogallol results in decreased expression of DCBLD2 mRNA | CTD | PMID:20362636 | Dcbld2 | Rat | pyrogallol | multiple interactions | ISO | Dcbld2 (Mus musculus) | 6480464 | Silymarin inhibits the reaction [Pyrogallol results in decreased expression of DCBLD2 mRNA] | CTD | PMID:20362636 | Dcbld2 | Rat | quercetin | increases expression | ISO | DCBLD2 (Homo sapiens) | 6480464 | Quercetin results in increased expression of DCBLD2 mRNA | CTD | PMID:21632981 | Dcbld2 | Rat | raloxifene | multiple interactions | ISO | DCBLD2 (Homo sapiens) | 6480464 | [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of DCBLD2 mRNA | CTD | PMID:19059307 | Dcbld2 | Rat | rotenone | decreases expression | EXP | | 6480464 | Rotenone results in decreased expression of DCBLD2 mRNA | CTD | PMID:28374803 | Dcbld2 | Rat | rotenone | increases expression | ISO | Dcbld2 (Mus musculus) | 6480464 | Rotenone results in increased expression of DCBLD2 mRNA | CTD | PMID:32937126 | Dcbld2 | Rat | SB 431542 | multiple interactions | ISO | DCBLD2 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of DCBLD2 mRNA | CTD | PMID:27188386 | Dcbld2 | Rat | sodium arsenate | multiple interactions | ISO | DCBLD2 (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of DCBLD2 mRNA | CTD | PMID:32525701 | Dcbld2 | Rat | sodium arsenite | decreases expression | ISO | DCBLD2 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of DCBLD2 mRNA | CTD | PMID:34032870 | Dcbld2 | Rat | succimer | multiple interactions | ISO | Dcbld2 (Mus musculus) | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in increased expression of DCBLD2 mRNA | CTD | PMID:21641980 | Dcbld2 | Rat | sulindac sulfide | increases expression | ISO | DCBLD2 (Homo sapiens) | 6480464 | sulindac sulfide results in increased expression of DCBLD2 mRNA | CTD | PMID:12734198 | Dcbld2 | Rat | sunitinib | decreases expression | ISO | DCBLD2 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of DCBLD2 mRNA | CTD | PMID:31533062 | Dcbld2 | Rat | tamoxifen | multiple interactions | ISO | DCBLD2 (Homo sapiens) | 6480464 | [Tamoxifen co-treated with ESR2 protein] results in increased expression of DCBLD2 mRNA | CTD | PMID:19059307 | Dcbld2 | Rat | temozolomide | decreases expression | ISO | DCBLD2 (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of DCBLD2 mRNA | CTD | PMID:31758290 | Dcbld2 | Rat | tetrachloromethane | increases expression | ISO | Dcbld2 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of DCBLD2 mRNA | CTD | PMID:17484886 | Dcbld2 | Rat | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of DCBLD2 mRNA | CTD | PMID:31150632 | Dcbld2 | Rat | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of DCBLD2 mRNA] | CTD | PMID:31150632 | Dcbld2 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of DCBLD2 mRNA | CTD | PMID:23411599 | Dcbld2 | Rat | thiram | increases expression | ISO | DCBLD2 (Homo sapiens) | 6480464 | Thiram results in increased expression of DCBLD2 mRNA | CTD | PMID:38568856 | Dcbld2 | Rat | titanium dioxide | decreases methylation | ISO | Dcbld2 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of DCBLD2 promoter | CTD | PMID:35295148 | Dcbld2 | Rat | titanium dioxide | increases methylation | ISO | Dcbld2 (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of DCBLD2 promoter | CTD | PMID:35295148 | Dcbld2 | Rat | trichostatin A | multiple interactions | ISO | DCBLD2 (Homo sapiens) | 6480464 | [[Decitabine co-treated with trichostatin A] affects the methylation of DCBLD2 promoter] which affects the expression of DCBLD2 mRNA more ... | CTD | PMID:18314483 and PMID:27188386 | Dcbld2 | Rat | tris(2-butoxyethyl) phosphate | affects expression | ISO | DCBLD2 (Homo sapiens) | 6480464 | tris(2-butoxyethyl) phosphate affects the expression of DCBLD2 mRNA | CTD | PMID:29024780 | Dcbld2 | Rat | valproic acid | decreases methylation | ISO | DCBLD2 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of DCBLD2 gene | CTD | PMID:29154799 | Dcbld2 | Rat | valproic acid | affects splicing | EXP | | 6480464 | Valproic Acid affects the splicing of DCBLD2 mRNA | CTD | PMID:29427782 | Dcbld2 | Rat | valproic acid | decreases expression | ISO | DCBLD2 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of DCBLD2 mRNA | CTD | PMID:23179753 | Dcbld2 | Rat | vorinostat | decreases expression | ISO | DCBLD2 (Homo sapiens) | 6480464 | vorinostat results in decreased expression of DCBLD2 mRNA | CTD | PMID:27188386 | Dcbld2 | Rat | zinc atom | increases expression | ISO | DCBLD2 (Homo sapiens) | 6480464 | Zinc results in increased expression of DCBLD2 mRNA | CTD | PMID:15984569 | Dcbld2 | Rat | zinc(0) | increases expression | ISO | DCBLD2 (Homo sapiens) | 6480464 | Zinc results in increased expression of DCBLD2 mRNA | CTD | PMID:15984569 | |