Csrp1 (cysteine and glycine-rich protein 1) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Csrp1 (cysteine and glycine-rich protein 1) Rattus norvegicus
Analyze
Symbol: Csrp1
Name: cysteine and glycine-rich protein 1
RGD ID: 62053
Description: Predicted to enable actinin binding activity. Predicted to be a structural constituent of muscle. Predicted to be involved in muscle tissue development and sarcomere organization. Predicted to be active in Z disc and nucleus. Orthologous to human CSRP1 (cysteine and glycine rich protein 1); INTERACTS WITH 1,2,4-trimethylbenzene; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: CRP; CRP1; Csrp; Csrp 1; cysteine rich protein; cysteine rich protein 1; cysteine-rich protein 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81349,709,928 - 49,731,141 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1349,709,914 - 49,731,139 (+)EnsemblGRCr8
mRatBN7.21347,158,171 - 47,179,388 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1347,167,789 - 47,179,384 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1349,767,088 - 49,788,318 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01351,055,154 - 51,076,383 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01348,318,235 - 48,339,461 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01352,553,843 - 52,575,054 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1352,553,775 - 52,575,051 (+)Ensemblrn6Rnor6.0
Rnor_5.01357,601,914 - 57,623,354 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41348,750,202 - 48,775,815 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1347,476,683 - 47,496,851 (+)NCBICelera
RGSC_v3.11348,764,244 - 48,789,856 (+)NCBI
RH 3.4 Map13149.8RGD
Cytogenetic Map13q13NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2,4-trimethylbenzene  (EXP)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4,4'-trichlorobiphenyl  (ISO)
2,4,6-tribromophenol  (ISO)
2,6-dimethoxyphenol  (ISO)
2-butoxyethanol  (ISO)
2-methylcholine  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (ISO)
5-fluorouracil  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
acrolein  (ISO)
actinomycin D  (ISO)
aflatoxin B1  (EXP)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
amiodarone  (EXP)
amitrole  (EXP)
ammonium chloride  (EXP)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzbromarone  (EXP)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (EXP,ISO)
bleomycin A2  (EXP)
Brodifacoum  (EXP)
buspirone  (EXP)
butan-1-ol  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
cadmium sulfate  (ISO)
captan  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (EXP)
choline  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
clobetasol  (ISO)
clofibrate  (EXP)
cobalt dichloride  (EXP,ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumarin  (EXP)
Cuprizon  (EXP)
cyclosporin A  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP,ISO)
dicyclanil  (ISO)
diethyl maleate  (EXP)
dihydroartemisinin  (ISO)
diquat  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
ethanol  (ISO)
fenamidone  (ISO)
fenthion  (ISO)
flutamide  (EXP)
folic acid  (ISO)
folpet  (ISO)
FR900359  (ISO)
furfural  (ISO)
genistein  (ISO)
gentamycin  (EXP)
graphite  (ISO)
indole-3-methanol  (EXP)
inulin  (ISO)
isoflavones  (EXP)
ivermectin  (ISO)
L-ascorbic acid  (EXP)
L-ethionine  (EXP)
L-methionine  (ISO)
lead diacetate  (ISO)
leflunomide  (EXP,ISO)
mercury dibromide  (ISO)
methidathion  (ISO)
methylseleninic acid  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
nefazodone  (EXP)
nimesulide  (EXP)
nitrates  (ISO)
Nutlin-3  (ISO)
okadaic acid  (ISO)
omeprazole  (EXP)
oxycodone  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
PCB138  (ISO)
pentanal  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenformin  (EXP)
phenylmercury acetate  (ISO)
pirinixic acid  (EXP,ISO)
propanal  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
tamibarotene  (ISO)
temozolomide  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (EXP)
tunicamycin  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)
vitamin E  (ISO)
vorinostat  (ISO)
XL147  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA)
nucleus  (IBA,IEA,ISO)
Z disc  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence. Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
4. Isolation and developmental expression of a rat cDNA encoding a cysteine-rich zinc finger protein. McLaughlin CR, etal., Nucleic Acids Res 1994 Dec 11;22(24):5477-83.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
10. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
11. Analysis of the human cysteine-rich protein gene (CSRP), assignment to chromosome 1q24-1q32, and identification of an associated MspI polymorphism. Wang X, etal., Genomics 1992 Oct;14(2):391-7.
12. cDNA cloning of the basement membrane chondroitin sulfate proteoglycan core protein, bamacan: a five domain structure including coiled-coil motifs. Wu RR and Couchman JR, J Cell Biol 1997 Jan 27;136(2):433-44.
Additional References at PubMed
PMID:15489334   PMID:19056867   PMID:21423176   PMID:22658674   PMID:23376485   PMID:23382103   PMID:26924529  


Genomics

Comparative Map Data
Csrp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81349,709,928 - 49,731,141 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1349,709,914 - 49,731,139 (+)EnsemblGRCr8
mRatBN7.21347,158,171 - 47,179,388 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1347,167,789 - 47,179,384 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1349,767,088 - 49,788,318 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01351,055,154 - 51,076,383 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01348,318,235 - 48,339,461 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01352,553,843 - 52,575,054 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1352,553,775 - 52,575,051 (+)Ensemblrn6Rnor6.0
Rnor_5.01357,601,914 - 57,623,354 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41348,750,202 - 48,775,815 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1347,476,683 - 47,496,851 (+)NCBICelera
RGSC_v3.11348,764,244 - 48,789,856 (+)NCBI
RH 3.4 Map13149.8RGD
Cytogenetic Map13q13NCBI
CSRP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381201,483,530 - 201,507,123 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1201,483,530 - 201,513,100 (-)Ensemblhg38GRCh38
GRCh371201,452,658 - 201,476,251 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361199,719,283 - 199,742,873 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341198,184,316 - 198,207,907NCBI
Celera1174,576,528 - 174,600,256 (-)NCBICelera
Cytogenetic Map1q32.1NCBI
HuRef1172,618,670 - 172,642,392 (-)NCBIHuRef
CHM1_11202,874,808 - 202,898,528 (-)NCBICHM1_1
T2T-CHM13v2.01200,741,308 - 200,764,907 (-)NCBIT2T-CHM13v2.0
Csrp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391135,614,650 - 135,679,970 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1135,647,799 - 135,679,970 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381135,720,063 - 135,752,229 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1135,720,061 - 135,752,232 (+)Ensemblmm10GRCm38
MGSCv371137,625,774 - 137,648,806 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361137,545,608 - 137,568,640 (+)NCBIMGSCv36mm8
Celera1138,360,910 - 138,386,389 (+)NCBICelera
Cytogenetic Map1E4NCBI
cM Map159.23NCBI
Csrp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540637,595,420 - 37,615,612 (-)Ensembl
ChiLan1.0NW_00495540637,595,481 - 37,615,384 (-)NCBIChiLan1.0ChiLan1.0
CSRP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2147,874,304 - 47,898,181 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1147,839,016 - 47,862,864 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01177,081,772 - 177,105,448 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11181,382,994 - 181,406,863 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1181,382,994 - 181,406,863 (-)EnsemblpanPan2panpan1.1
CSRP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.171,400,650 - 1,421,918 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl71,397,912 - 1,421,007 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha71,450,814 - 1,472,009 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.071,407,306 - 1,428,562 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl71,404,765 - 1,428,562 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.171,394,963 - 1,416,145 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.071,503,000 - 1,524,132 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.071,527,323 - 1,548,513 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Csrp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934473,712,015 - 73,733,312 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365672,946,565 - 2,968,010 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365672,946,721 - 2,967,988 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CSRP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1023,843,134 - 23,864,016 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11023,843,130 - 23,864,020 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21028,377,362 - 28,398,060 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CSRP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12527,908,426 - 27,932,107 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2527,908,554 - 27,933,275 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605528,704,392 - 28,728,088 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Csrp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248079,235,783 - 9,247,615 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248079,226,747 - 9,247,004 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Csrp1
136 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:113
Count of miRNA genes:92
Interacting mature miRNAs:102
Transcripts:ENSRNOT00000011991
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134863963493639634Rat
10755495Bp387Blood pressure QTL 3873.78arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133721624190057603Rat
9589141Insul28Insulin level QTL 2810.820.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)131186625456866254Rat
6893344Cm79Cardiac mass QTL 791.50.04heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)134627292251216694Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1338975045103588154Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133992469384924693Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134874981487285480Rat
61391Bp5Blood pressure QTL 55.6arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)132485392569853925Rat
4889861Pur29Proteinuria QTL 2913.80.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133996821183286298Rat
2317040Aia21Adjuvant induced arthritis QTL 212.75joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)131238432057384320Rat
631645Bp121Blood pressure QTL 1213.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131746828262468282Rat
2317046Aia8Adjuvant induced arthritis QTL 83.9700000286102295joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)131238432057384320Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13742179187286911Rat
1331784Bp222Blood pressure QTL 2222.944arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)132433543255601132Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133708798382087983Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)134098358585983585Rat
724564Uae11Urinary albumin excretion QTL 115.7urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)134735425894285672Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1321120177109350286Rat
4145117Mcs27Mammary carcinoma susceptibility QTL 270.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)134599007750392939Rat
1558644Cm45Cardiac mass QTL 453.60.002heart mass (VT:0007028)heart wet weight (CMO:0000069)132624480871244808Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133379409678794096Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133992469384924693Rat
2303563Bw89Body weight QTL 896body mass (VT:0001259)body weight (CMO:0000012)133483494779834947Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1311081740103588154Rat
2301962Cm72Cardiac mass QTL 724.12heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)133379409660914504Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
12879477Bp401Blood pressure QTL 401arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133981472684814726Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133996821184968211Rat
6893338Cm76Cardiac mass QTL 7600.99heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)132624480871244808Rat
12879472Bp399Blood pressure QTL 399arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134778041850392939Rat
11530006Niddm72Non-insulin dependent diabetes mellitus QTL 720.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)133828629883286298Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131103588154Rat
9589164Gluco66Glucose level QTL 666.670.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)131771133662711336Rat
7411662Foco29Food consumption QTL 2920.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)131186625456866254Rat

Markers in Region
RH127850  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21347,178,985 - 47,179,201 (+)MAPPERmRatBN7.2
Rnor_6.01352,574,652 - 52,574,867NCBIRnor6.0
Rnor_5.01357,622,952 - 57,623,167UniSTSRnor5.0
RGSC_v3.41348,775,413 - 48,775,628UniSTSRGSC3.4
Celera1347,496,449 - 47,496,664UniSTS
RH 3.4 Map13147.9UniSTS
Cytogenetic Map13q13UniSTS
RH129346  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21347,179,080 - 47,179,308 (+)MAPPERmRatBN7.2
Rnor_6.01352,574,747 - 52,574,974NCBIRnor6.0
Rnor_5.01357,623,047 - 57,623,274UniSTSRnor5.0
RGSC_v3.41348,775,508 - 48,775,735UniSTSRGSC3.4
Celera1347,496,544 - 47,496,771UniSTS
Cytogenetic Map13q13UniSTS
RH94660  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81349,730,392 - 49,730,528 (+)Marker Load Pipeline
mRatBN7.21347,178,639 - 47,178,775 (+)MAPPERmRatBN7.2
Rnor_6.01352,574,306 - 52,574,441NCBIRnor6.0
Rnor_5.01357,622,606 - 57,622,741UniSTSRnor5.0
RGSC_v3.41348,775,067 - 48,775,202UniSTSRGSC3.4
Celera1347,496,103 - 47,496,238UniSTS
RH 3.4 Map13149.8UniSTS
Cytogenetic Map13q13UniSTS
PMC130177P2  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21347,178,957 - 47,179,359 (+)MAPPERmRatBN7.2
Rnor_6.01352,574,624 - 52,575,025NCBIRnor6.0
Rnor_5.01357,622,924 - 57,623,325UniSTSRnor5.0
RGSC_v3.41348,775,385 - 48,775,786UniSTSRGSC3.4
Celera1347,496,421 - 47,496,822UniSTS
Cytogenetic Map13q13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 161 91 90 59 92 59 6 356 192 11 140 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000011991   ⟹   ENSRNOP00000011991
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1349,709,914 - 49,731,139 (+)Ensembl
mRatBN7.2 Ensembl1347,167,789 - 47,179,384 (+)Ensembl
Rnor_6.0 Ensembl1352,553,775 - 52,575,051 (+)Ensembl
RefSeq Acc Id: NM_017148   ⟹   NP_058844
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81349,709,928 - 49,731,141 (+)NCBI
mRatBN7.21347,158,171 - 47,179,388 (+)NCBI
Rnor_6.01352,553,843 - 52,575,054 (+)NCBI
Rnor_5.01357,601,914 - 57,623,354 (+)NCBI
RGSC_v3.41348,750,202 - 48,775,815 (+)RGD
Celera1347,476,683 - 47,496,851 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_058844 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC52157 (Get FASTA)   NCBI Sequence Viewer  
  AAH62407 (Get FASTA)   NCBI Sequence Viewer  
  EDM09685 (Get FASTA)   NCBI Sequence Viewer  
  EDM09686 (Get FASTA)   NCBI Sequence Viewer  
  EDM09687 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000011991
GenBank Protein P47875 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_058844   ⟸   NM_017148
- UniProtKB: P47875 (UniProtKB/Swiss-Prot),   A0A8L2Q5C4 (UniProtKB/TrEMBL),   A6ICG1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000011991   ⟸   ENSRNOT00000011991
Protein Domains
LIM zinc-binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P47875-F1-model_v2 AlphaFold P47875 1-193 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698845
Promoter ID:EPDNEW_R9370
Type:multiple initiation site
Name:Csrp1_1
Description:cysteine and glycine-rich protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01352,553,833 - 52,553,893EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:62053 AgrOrtholog
BioCyc Gene G2FUF-18194 BioCyc
Ensembl Genes ENSRNOG00000008937 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000011991 ENTREZGENE
Gene3D-CATH Cysteine Rich Protein UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:5623423 IMAGE-MGC_LOAD
InterPro Znf_LIM UniProtKB/Swiss-Prot
KEGG Report rno:29276 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72506 IMAGE-MGC_LOAD
NCBI Gene Csrp1 ENTREZGENE
PANTHER CYSTEINE AND GLYCINE-RICH PROTEIN 1 UniProtKB/Swiss-Prot
  RHO-GTPASE-ACTIVATING PROTEIN LRG1 UniProtKB/Swiss-Prot
Pfam LIM UniProtKB/Swiss-Prot
PhenoGen Csrp1 PhenoGen
PROSITE LIM_DOMAIN_1 UniProtKB/Swiss-Prot
  LIM_DOMAIN_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000008937 RatGTEx
SMART LIM UniProtKB/Swiss-Prot
Superfamily-SCOP Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/Swiss-Prot
TIGR TC228642
UniProt A0A8L2Q5C4 ENTREZGENE, UniProtKB/TrEMBL
  A6ICG0_RAT UniProtKB/TrEMBL
  A6ICG1 ENTREZGENE, UniProtKB/TrEMBL
  A6ICG2_RAT UniProtKB/TrEMBL
  CSRP1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2003-04-09 Csrp1  cysteine and glycine-rich protein 1    cysteine rich protein 1  Name updated 629478 APPROVED
2002-06-10 Csrp1  cysteine rich protein 1      Name updated 70584 APPROVED
2001-12-06 Csrp 1  cysteine and glycine-rich protein 1      Symbol and Name updated to reflect Human and Mouse nomenclature 69665 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_domains contains four potential zinc fingers, two of the C4 class and two of the C2H2 class 61564