Pim3 (Pim-3 proto-oncogene, serine/threonine kinase) - Rat Genome Database

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Gene: Pim3 (Pim-3 proto-oncogene, serine/threonine kinase) Rattus norvegicus
Analyze
Symbol: Pim3
Name: Pim-3 proto-oncogene, serine/threonine kinase
RGD ID: 620462
Description: Enables protein serine/threonine kinase activity. Involved in cellular response to forskolin. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Orthologous to human PIM3 (Pim-3 proto-oncogene, serine/threonine kinase); INTERACTS WITH 1,2,4-trimethylbenzene; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: kinase induced by depolarization; LOC100364466; pim-3 oncogene; protein kinase Kid-1; proviral integration site 3; serine threonine kinase pim3; serine threonine kinase-like; serine/threonine protein kinase pim-3; serine/threonine-protein kinase pim-3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87121,822,076 - 121,836,257 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7121,832,742 - 121,836,259 (+)EnsemblGRCr8
mRatBN7.27119,953,377 - 119,956,587 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7119,953,175 - 119,956,587 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx7121,704,664 - 121,707,874 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07123,930,846 - 123,934,056 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07123,894,096 - 123,897,306 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.07129,856,467 - 129,863,441 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7129,860,114 - 129,863,441 (+)Ensemblrn6Rnor6.0
Rnor_5.07129,544,588 - 129,547,908 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47127,167,984 - 127,172,018 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7116,427,171 - 116,430,499 (+)NCBICelera
RGSC_v3.17127,202,213 - 127,206,248 (+)NCBI
Cytogenetic Map7q34NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2,4-trimethylbenzene  (EXP)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,6-dinitrotoluene  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
all-trans-retinoic acid  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
bromobenzene  (EXP)
buspirone  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
ciguatoxin CTX1B  (ISO)
clobetasol  (ISO)
cobalt dichloride  (EXP)
cocaine  (EXP)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
corticosterone  (EXP)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
dexamethasone  (EXP)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
diquat  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
fluoranthene  (ISO)
folic acid  (ISO)
genistein  (EXP)
gentamycin  (EXP)
GSK-J4  (ISO)
hydrogen cyanide  (ISO)
hydrogen peroxide  (ISO)
isoprenaline  (ISO)
leflunomide  (ISO)
lipopolysaccharide  (ISO)
methamphetamine  (ISO)
methylmercury chloride  (ISO)
naphthalenes  (EXP)
nefazodone  (EXP)
nevirapine  (ISO)
nickel atom  (ISO)
nimesulide  (EXP)
ochratoxin A  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
parathion  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
potassium cyanide  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (EXP)
resveratrol  (ISO)
rotenone  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
testosterone  (EXP)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (EXP,ISO)
triphenyl phosphate  (ISO)
tungsten  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
venlafaxine hydrochloride  (EXP)
zinc atom  (EXP,ISO)
zinc sulfate  (EXP)
zinc(0)  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IEA)
cytosol  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. KID-1, a protein kinase induced by depolarization in brain. Feldman JD, etal., J Biol Chem 1998 Jun 26;273(26):16535-43.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:17270021   PMID:18593906   PMID:19229879   PMID:19505587   PMID:21099329   PMID:21181358   PMID:26269675   PMID:28214201   PMID:38148455  


Genomics

Comparative Map Data
Pim3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87121,822,076 - 121,836,257 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7121,832,742 - 121,836,259 (+)EnsemblGRCr8
mRatBN7.27119,953,377 - 119,956,587 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7119,953,175 - 119,956,587 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx7121,704,664 - 121,707,874 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07123,930,846 - 123,934,056 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07123,894,096 - 123,897,306 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.07129,856,467 - 129,863,441 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7129,860,114 - 129,863,441 (+)Ensemblrn6Rnor6.0
Rnor_5.07129,544,588 - 129,547,908 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47127,167,984 - 127,172,018 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7116,427,171 - 116,430,499 (+)NCBICelera
RGSC_v3.17127,202,213 - 127,206,248 (+)NCBI
Cytogenetic Map7q34NCBI
PIM3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382249,960,772 - 49,964,072 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2249,960,463 - 49,964,075 (+)Ensemblhg38GRCh38
GRCh372250,354,420 - 50,357,720 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362248,740,165 - 48,743,724 (+)NCBIBuild 36Build 36hg18NCBI36
Build 342248,675,021 - 48,677,378NCBI
Celera2234,275,438 - 34,279,529 (+)NCBICelera
Cytogenetic Map22q13.33NCBI
HuRef2233,300,609 - 33,304,139 (+)NCBIHuRef
CHM1_12250,312,881 - 50,316,458 (+)NCBICHM1_1
T2T-CHM13v2.02250,465,433 - 50,468,733 (+)NCBIT2T-CHM13v2.0
Pim3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391588,746,397 - 88,749,929 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1588,746,389 - 88,749,929 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381588,862,194 - 88,865,726 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1588,862,186 - 88,865,726 (+)Ensemblmm10GRCm38
MGSCv371588,692,624 - 88,696,156 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361588,689,960 - 88,693,492 (+)NCBIMGSCv36mm8
Celera1590,988,435 - 90,991,967 (+)NCBICelera
Cytogenetic Map15E3NCBI
cM Map1544.36NCBI
Pim3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495541333,068,033 - 33,071,344 (+)NCBIChiLan1.0ChiLan1.0
PIM3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22359,863,528 - 59,867,077 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12262,550,188 - 62,553,498 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02230,186,716 - 30,190,270 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12249,190,473 - 49,192,975 (+)NCBIPanPan1.1PanPan1.1panPan2
PIM3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11017,260,590 - 17,262,175 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1017,239,225 - 17,242,064 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01017,988,548 - 17,991,389 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1017,988,907 - 17,991,842 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11017,711,939 - 17,714,778 (-)NCBIUMICH_Zoey_3.1
UU_Cfam_GSD_1.01018,167,193 - 18,170,033 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Pim3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945805,347 - 808,028 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936629805,338 - 808,028 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936629805,343 - 808,028 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PIM3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl5677,705 - 680,695 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.15677,705 - 680,690 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.25111,022,429 - 111,032,418 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PIM3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11932,466,432 - 32,470,001 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1932,466,771 - 32,470,006 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604592,928,922 - 92,932,464 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pim3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624752710,960 - 715,342 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624752710,959 - 715,035 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Pim3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11258,185,532 - 258,189,294 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Pim3
155 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:156
Count of miRNA genes:107
Interacting mature miRNAs:130
Transcripts:ENSRNOT00000043461
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354582Stl11Serum triglyceride level QTL 113.42blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7121393075137014596Rat
1300112Bp183Blood pressure QTL 1833.51arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)7119280025135560836Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)782111245123048330Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7104186212135371468Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)793302009131686183Rat
61397Bw17Body weight QTL 176.3body mass (VT:0001259)body weight (CMO:0000012)795485047137014596Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7115313999136544683Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)746307490127866166Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)785043242130043242Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)785497398130497398Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)792362341137014596Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)783626689128626689Rat
631529Tls2T-lymphoma susceptibility QTL 200.001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)782111382132099989Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)798549867137014596Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)777807807122807807Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)782111245123048330Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)740540077123682549Rat
1331748Bp215Blood pressure QTL 2154.043arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7110725024135371468Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)7100548246137014596Rat
1331746Kidm9Kidney mass QTL 93.934kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)782111245134948181Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)777807807122807807Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)7116269196132020414Rat
1582240Sffal1Serum free fatty acids level QTL 13.40.0021blood free fatty acid amount (VT:0001553)serum free fatty acids level (CMO:0000547)7118556868125929417Rat
10402855Bp379Blood pressure QTL 3790.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)778682549123682549Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)771827901136544683Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 161 91 90 59 92 59 6 356 192 11 140 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000043461   ⟹   ENSRNOP00000045396
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7121,832,742 - 121,836,259 (+)Ensembl
mRatBN7.2 Ensembl7119,953,175 - 119,956,587 (+)Ensembl
Rnor_6.0 Ensembl7129,860,327 - 129,863,441 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000085835   ⟹   ENSRNOP00000072553
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7121,832,742 - 121,836,259 (+)Ensembl
mRatBN7.2 Ensembl7119,953,175 - 119,956,587 (+)Ensembl
Rnor_6.0 Ensembl7129,860,114 - 129,862,474 (+)Ensembl
RefSeq Acc Id: NM_022602   ⟹   NP_072124
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87121,833,045 - 121,836,255 (+)NCBI
mRatBN7.27119,953,377 - 119,956,587 (+)NCBI
Rnor_6.07129,856,467 - 129,863,441 (+)NCBI
Rnor_5.07129,544,588 - 129,547,908 (+)NCBI
RGSC_v3.47127,167,984 - 127,172,018 (+)RGD
Celera7116,427,171 - 116,430,499 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063264213   ⟹   XP_063120283
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87121,822,076 - 121,836,257 (+)NCBI
Protein Sequences
Protein RefSeqs NP_072124 (Get FASTA)   NCBI Sequence Viewer  
  XP_063120283 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC36065 (Get FASTA)   NCBI Sequence Viewer  
  AAC68900 (Get FASTA)   NCBI Sequence Viewer  
  AAH97317 (Get FASTA)   NCBI Sequence Viewer  
  EDL76522 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000045396.5
  ENSRNOP00000072553
GenBank Protein O70444 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_072124   ⟸   NM_022602
- UniProtKB: O70444 (UniProtKB/Swiss-Prot),   Q4V8M2 (UniProtKB/TrEMBL),   A0A0G2K399 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000045396   ⟸   ENSRNOT00000043461
Ensembl Acc Id: ENSRNOP00000072553   ⟸   ENSRNOT00000085835
RefSeq Acc Id: XP_063120283   ⟸   XM_063264213
- Peptide Label: isoform X1
- UniProtKB: O70444 (UniProtKB/Swiss-Prot),   A0A0G2K399 (UniProtKB/TrEMBL),   Q4V8M2 (UniProtKB/TrEMBL)
Protein Domains
Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O70444-F1-model_v2 AlphaFold O70444 1-326 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620462 AgrOrtholog
BioCyc Gene G2FUF-32484 BioCyc
Ensembl Genes ENSRNOG00000029698 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000043461.5 UniProtKB/Swiss-Prot
  ENSRNOT00000085835 ENTREZGENE
Gene3D-CATH Phosphorylase Kinase, domain 1 UniProtKB/Swiss-Prot
  Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7446368 IMAGE-MGC_LOAD
InterPro Kinase-like_dom_sf UniProtKB/Swiss-Prot
  PIM1/2/3 UniProtKB/Swiss-Prot
  PIM_Ser/Thr_kinase UniProtKB/Swiss-Prot
  Prot_kinase_dom UniProtKB/Swiss-Prot
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot
  Ser/Thr_kinase_AS UniProtKB/Swiss-Prot
KEGG Report rno:64534 UniProtKB/Swiss-Prot
MGC_CLONE MGC:114318 IMAGE-MGC_LOAD
NCBI Gene 64534 ENTREZGENE
PANTHER SERINE/THREONINE-PROTEIN KINASE PIM UniProtKB/Swiss-Prot
  SERINE/THREONINE-PROTEIN KINASE PIM-3 UniProtKB/Swiss-Prot
Pfam Pkinase UniProtKB/Swiss-Prot
PhenoGen Pim3 PhenoGen
PIRSF STPK_Pim-1 UniProtKB/Swiss-Prot
PROSITE PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot
  PROTEIN_KINASE_ST UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000029698 RatGTEx
SMART S_TKc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF56112 UniProtKB/Swiss-Prot
UniProt A0A0G2K399 ENTREZGENE, UniProtKB/TrEMBL
  A6K7H9_RAT UniProtKB/TrEMBL
  F1M9R1_RAT UniProtKB/TrEMBL
  O70444 ENTREZGENE, UniProtKB/Swiss-Prot
  Q4V8M2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-07-10 Pim3  Pim-3 proto-oncogene, serine/threonine kinase  Pim3  pim-3 oncogene  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-04-17 Pim3  pim-3 oncogene  LOC100364466  serine threonine kinase-like  Data merged from RGD:2320994 737654 PROVISIONAL
2010-05-05 LOC100364466  serine threonine kinase-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-09-09 Pim3  pim-3 oncogene  Pim3  proviral integration site 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-25 Pim3  proviral integration site 3  Pim3  serine/threonine-protein kinase pim-3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Pim3  serine/threonine-protein kinase pim-3    serine threonine kinase pim3  Name updated 1299863 APPROVED
2002-08-07 Pim3  serine threonine kinase pim3      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_protein 326 amino acids 633695
gene_regulation induced by membrane depolarization in neurons 633695