(S)-amphetamine increases expression ISO Pax8 (Mus musculus) 6480464 Dextroamphetamine results in increased expression of PAX8 mRNA CTD PMID:12558987 (S)-nicotine increases expression ISO PAX8 (Homo sapiens) 6480464 Nicotine results in increased expression of PAX8 mRNA CTD PMID:23825647 (S)-nicotine decreases expression EXP 6480464 Nicotine results in decreased expression of PAX8 mRNA CTD PMID:26776438 1,2-dichloroethane increases expression ISO Pax8 (Mus musculus) 6480464 ethylene dichloride results in increased expression of PAX8 mRNA CTD PMID:28960355 2,2',5,5'-tetrachlorobiphenyl increases expression ISO PAX8 (Homo sapiens) 6480464 2 more ... CTD PMID:36804509 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Pax8 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of PAX8 mRNA CTD PMID:24058054 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Pax8 (Mus musculus) 6480464 Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to PAX8 promoter] CTD PMID:19654925 4,4'-sulfonyldiphenol multiple interactions ISO Pax8 (Mus musculus) 6480464 [bisphenol S co-treated with Tretinoin] results in decreased expression of PAX8 mRNA CTD PMID:30951980 5-aza-2'-deoxycytidine multiple interactions ISO PAX8 (Homo sapiens) 6480464 [Decitabine co-treated with Tretinoin] results in increased expression of PAX8 mRNA CTD PMID:19524134 acetamide increases expression EXP 6480464 acetamide results in increased expression of PAX8 mRNA CTD PMID:31881176 all-trans-retinoic acid multiple interactions ISO PAX8 (Homo sapiens) 6480464 [decitabine co-treated with Tretinoin] results in increased expression of PAX8 mRNA CTD PMID:19524134 all-trans-retinoic acid multiple interactions ISO Pax8 (Mus musculus) 6480464 [bisphenol F co-treated with Tretinoin] results in decreased expression of PAX8 mRNA and [bisphenol S co-treated with Tretinoin] results in decreased expression of PAX8 mRNA CTD PMID:30951980 all-trans-retinoic acid decreases expression ISO PAX8 (Homo sapiens) 6480464 Tretinoin results in decreased expression of PAX8 mRNA CTD PMID:21924320 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of PAX8 mRNA CTD PMID:16483693 antirheumatic drug decreases expression ISO PAX8 (Homo sapiens) 6480464 Antirheumatic Agents results in decreased expression of PAX8 mRNA CTD PMID:24449571 aristolochic acid A decreases expression ISO PAX8 (Homo sapiens) 6480464 aristolochic acid I results in decreased expression of PAX8 mRNA CTD PMID:33212167 bathocuproine disulfonic acid multiple interactions EXP 6480464 bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid results in decreased expression of PAX8 mRNA] CTD PMID:11108245 benzo[a]pyrene multiple interactions ISO Pax8 (Mus musculus) 6480464 Benzo(a)pyrene promotes the reaction [AHR protein binds to PAX8 promoter] CTD PMID:19654925 bis(2-ethylhexyl) phthalate increases expression EXP 6480464 Diethylhexyl Phthalate results in increased expression of PAX8 protein CTD PMID:30543897 bis(2-ethylhexyl) phthalate decreases expression ISO Pax8 (Mus musculus) 6480464 Diethylhexyl Phthalate results in decreased expression of PAX8 mRNA CTD PMID:32303808 bis(2-ethylhexyl) phthalate multiple interactions ISO Pax8 (Mus musculus) 6480464 Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of PAX8 mRNA] CTD PMID:32303808 bis(2-ethylhexyl) phthalate multiple interactions ISO PAX8 (Homo sapiens) 6480464 [Diethylhexyl Phthalate results in increased abundance of mono(2-ethyl-5-hydroxyhexyl) phthalate] which results in increased expression of PAX8 mRNA and TSHR protein affects the reaction [Diethylhexyl Phthalate results in increased expression of PAX8 protein] CTD PMID:30543897 and PMID:34708313 bis(2-ethylhexyl) phthalate increases expression ISO PAX8 (Homo sapiens) 6480464 Diethylhexyl Phthalate results in increased expression of PAX8 mRNA and Diethylhexyl Phthalate results in increased expression of PAX8 protein CTD PMID:30543897 bisphenol A increases expression ISO PAX8 (Homo sapiens) 6480464 bisphenol A results in increased expression of PAX8 mRNA CTD PMID:23238275 bisphenol A increases expression ISO Pax8 (Mus musculus) 6480464 bisphenol A results in increased expression of PAX8 mRNA CTD PMID:32156529 bisphenol A increases methylation ISO PAX8 (Homo sapiens) 6480464 bisphenol A results in increased methylation of PAX8 gene CTD PMID:31601247 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of PAX8 mRNA CTD PMID:25181051 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of PAX8 mRNA and bisphenol A results in increased expression of PAX8 protein CTD PMID:23238275 and PMID:26827900 bisphenol F multiple interactions ISO Pax8 (Mus musculus) 6480464 [bisphenol F co-treated with Tretinoin] results in decreased expression of PAX8 mRNA CTD PMID:30951980 bisphenol F decreases expression ISO Pax8 (Mus musculus) 6480464 bisphenol F results in decreased expression of PAX8 mRNA CTD PMID:30951980 bromobenzene increases expression EXP 6480464 bromobenzene results in increased expression of PAX8 mRNA CTD PMID:32479839 cadmium dichloride increases methylation EXP 6480464 Cadmium Chloride results in increased methylation of PAX8 promoter CTD PMID:22457795 calcium atom affects expression EXP 6480464 Calcium affects the expression of PAX8 mRNA CTD PMID:15913539 calcium(0) affects expression EXP 6480464 Calcium affects the expression of PAX8 mRNA CTD PMID:15913539 cannabidiol affects methylation EXP 6480464 Cannabidiol affects the methylation of PAX8 gene CTD PMID:30521419 carmustine decreases expression ISO PAX8 (Homo sapiens) 6480464 Carmustine results in decreased expression of PAX8 mRNA CTD PMID:15980968 CGP 52608 multiple interactions ISO PAX8 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to PAX8 gene] CTD PMID:28238834 cisplatin affects response to substance ISO PAX8 (Homo sapiens) 6480464 PAX8 protein affects the susceptibility to Cisplatin CTD PMID:16217747 cocaine increases expression ISO PAX8 (Homo sapiens) 6480464 Cocaine results in increased expression of PAX8 mRNA CTD PMID:12629581 colforsin daropate hydrochloride increases expression ISO PAX8 (Homo sapiens) 6480464 Colforsin results in increased expression of PAX8 mRNA and Colforsin results in increased expression of PAX8 protein CTD PMID:15961562 corn oil affects expression EXP 6480464 Corn Oil affects the expression of PAX8 mRNA CTD PMID:16360708 decabromodiphenyl ether increases expression EXP 6480464 decabromobiphenyl ether results in increased expression of PAX8 mRNA CTD PMID:23914054 decabromodiphenyl ether decreases expression EXP 6480464 decabromobiphenyl ether results in decreased expression of PAX8 mRNA CTD PMID:30844666 endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of PAX8 mRNA CTD PMID:29391264 ethylparaben increases expression ISO PAX8 (Homo sapiens) 6480464 ethyl-p-hydroxybenzoate results in increased expression of PAX8 mRNA CTD PMID:37690743 flavonoids decreases expression EXP 6480464 Flavonoids results in decreased expression of PAX8 mRNA CTD PMID:18035473 folic acid decreases expression ISO Pax8 (Mus musculus) 6480464 Folic Acid results in decreased expression of PAX8 mRNA CTD PMID:25629700 folic acid affects methylation ISO PAX8 (Homo sapiens) 6480464 Folic Acid affects the methylation of PAX8 gene CTD PMID:29546377 furan increases expression EXP 6480464 furan results in increased expression of PAX8 mRNA CTD PMID:25539665 glyphosate increases expression EXP 6480464 Glyphosate results in increased expression of PAX8 mRNA CTD PMID:36462676 lead(0) decreases expression ISO PAX8 (Homo sapiens) 6480464 Lead results in decreased expression of PAX8 mRNA CTD PMID:19921347 lipopolysaccharide increases expression ISO Pax8 (Mus musculus) 6480464 Lipopolysaccharides results in increased expression of PAX8 mRNA CTD PMID:12057914 mono(2-ethyl-5-hydroxyhexyl) phthalate multiple interactions ISO PAX8 (Homo sapiens) 6480464 [Diethylhexyl Phthalate results in increased abundance of mono(2-ethyl-5-hydroxyhexyl) phthalate] which results in increased expression of PAX8 mRNA CTD PMID:34708313 mono(2-ethylhexyl) phthalate decreases expression ISO PAX8 (Homo sapiens) 6480464 mono-(2-ethylhexyl)phthalate results in decreased expression of PAX8 protein CTD PMID:36005737 nicotine increases expression ISO PAX8 (Homo sapiens) 6480464 Nicotine results in increased expression of PAX8 mRNA CTD PMID:23825647 nicotine decreases expression EXP 6480464 Nicotine results in decreased expression of PAX8 mRNA CTD PMID:26776438 paracetamol decreases expression ISO PAX8 (Homo sapiens) 6480464 Acetaminophen results in decreased expression of PAX8 mRNA CTD PMID:26690555 paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of PAX8 mRNA CTD PMID:33387578 paracetamol increases expression ISO PAX8 (Homo sapiens) 6480464 Acetaminophen results in increased expression of PAX8 mRNA CTD PMID:29067470 perchlorate decreases expression EXP 6480464 perchlorate results in decreased expression of PAX8 mRNA CTD PMID:35385113 perfluorobutanesulfonic acid affects expression EXP 6480464 perfluorobutanesulfonic acid affects the expression of PAX8 mRNA CTD PMID:22071372 perfluorobutyric acid increases expression EXP 6480464 perfluorobutyric acid results in increased expression of PAX8 mRNA CTD PMID:22071372 perfluorododecanoic acid increases expression EXP 6480464 perfluorododecanoic acid results in increased expression of PAX8 mRNA CTD PMID:22071372 perfluorohexanesulfonic acid increases expression EXP 6480464 perfluorohexanesulfonic acid results in increased expression of PAX8 mRNA CTD PMID:22071372 perfluorohexanesulfonic acid decreases expression ISO PAX8 (Homo sapiens) 6480464 perfluorohexanesulfonic acid results in decreased expression of PAX8 mRNA CTD PMID:25812627 perfluorohexanoic acid increases expression EXP 6480464 perfluorohexanoic acid results in increased expression of PAX8 mRNA CTD PMID:22071372 perfluorononanoic acid increases expression EXP 6480464 perfluoro-n-nonanoic acid results in increased expression of PAX8 mRNA CTD PMID:22071372 perfluorononanoic acid decreases expression ISO PAX8 (Homo sapiens) 6480464 perfluoro-n-nonanoic acid results in decreased expression of PAX8 mRNA CTD PMID:25812627 perfluorooctane-1-sulfonic acid affects expression EXP 6480464 perfluorooctane sulfonic acid affects the expression of PAX8 mRNA CTD PMID:22071372 perfluorooctane-1-sulfonic acid decreases expression ISO PAX8 (Homo sapiens) 6480464 perfluorooctane sulfonic acid results in decreased expression of PAX8 mRNA CTD PMID:25812627 perfluorooctanoic acid increases expression EXP 6480464 perfluorooctanoic acid results in increased expression of PAX8 mRNA and perfluorooctanoic acid results in increased expression of PAX8 protein CTD PMID:22071372 and PMID:34246126 perfluorooctanoic acid decreases expression ISO PAX8 (Homo sapiens) 6480464 perfluorooctanoic acid results in decreased expression of PAX8 mRNA CTD PMID:25812627 perfluorooctanoic acid increases expression ISO PAX8 (Homo sapiens) 6480464 perfluorooctanoic acid results in increased expression of PAX8 mRNA and perfluorooctanoic acid results in increased expression of PAX8 protein CTD PMID:34246126 perfluoroundecanoic acid increases expression EXP 6480464 perfluoroundecanoic acid results in increased expression of PAX8 mRNA CTD PMID:22071372 potassium iodide multiple interactions EXP 6480464 Potassium Iodide inhibits the reaction [TSHB protein promotes the reaction [PAX8 protein binds to SLC5A5 enhancer]] more ... CTD PMID:27568464 pyrrolidine dithiocarbamate multiple interactions EXP 6480464 bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid results in decreased expression of PAX8 mRNA] and PAX8 protein inhibits the reaction [pyrrolidine dithiocarbamic acid results in decreased activity of TPO promoter] CTD PMID:11108245 pyrrolidine dithiocarbamate decreases expression EXP 6480464 pyrrolidine dithiocarbamic acid results in decreased expression of PAX8 mRNA CTD PMID:11108245 pyrrolidine dithiocarbamate decreases chemical synthesis EXP 6480464 pyrrolidine dithiocarbamic acid results in decreased chemical synthesis of PAX8 protein CTD PMID:11108245 quercetin decreases expression ISO PAX8 (Homo sapiens) 6480464 Quercetin results in decreased expression of PAX8 mRNA CTD PMID:15309432 resveratrol multiple interactions ISO PAX8 (Homo sapiens) 6480464 [Plant Extracts co-treated with Resveratrol] results in decreased expression of PAX8 mRNA and NOTCH1 mutant form inhibits the reaction [Resveratrol results in increased expression of PAX8 mRNA] CTD PMID:23557933 and PMID:23594881 resveratrol decreases expression EXP 6480464 resveratrol results in decreased expression of PAX8 mRNA CTD PMID:28668442 resveratrol increases expression ISO PAX8 (Homo sapiens) 6480464 resveratrol results in increased expression of PAX8 mRNA and resveratrol results in increased expression of PAX8 protein CTD PMID:23594881 silicon dioxide increases expression EXP 6480464 Silicon Dioxide results in increased expression of PAX8 mRNA CTD PMID:32721576 silicon dioxide decreases methylation ISO PAX8 (Homo sapiens) 6480464 Silicon Dioxide results in decreased methylation of PAX8 gene CTD PMID:34973136 sirolimus multiple interactions ISO PAX8 (Homo sapiens) 6480464 Sirolimus promotes the reaction [TP73 protein affects the activity of PAX8 protein] CTD PMID:21245298 sodium dichromate decreases expression ISO Pax8 (Mus musculus) 6480464 sodium bichromate results in decreased expression of PAX8 mRNA CTD PMID:31558096 sodium perchlorate increases expression EXP 6480464 sodium perchlorate results in increased expression of PAX8 protein CTD PMID:29139221 streptozocin multiple interactions ISO Pax8 (Mus musculus) 6480464 [Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of PAX8 mRNA and Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of PAX8 mRNA] CTD PMID:32303808 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of PAX8 mRNA CTD PMID:34492290 trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of PAX8 mRNA CTD PMID:33387578 triptonide increases expression ISO Pax8 (Mus musculus) 6480464 triptonide results in increased expression of PAX8 mRNA CTD PMID:33045310 urethane decreases expression ISO PAX8 (Homo sapiens) 6480464 Urethane results in decreased expression of PAX8 mRNA CTD PMID:28818685 valproic acid increases methylation ISO PAX8 (Homo sapiens) 6480464 Valproic Acid results in increased methylation of PAX8 gene CTD PMID:29154799