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Gene: Pax3 (paired box 3) Rattus norvegicus

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Symbol:

Pax3

Name:

paired box 3

RGD ID:

620431

Description:

Predicted to enable several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and transcription coregulator binding activity. Predicted to be involved in nervous system development and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including nervous system development; regulation of somitogenesis; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in Waardenburg syndrome; Waardenburg syndrome type 1; Waardenburg syndrome type 3; alveolar rhabdomyosarcoma; and craniofacial-deafness-hand syndrome. Orthologous to human PAX3 (paired box 3); INTERACTS WITH (S)-nicotine; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

homeodomain protein PAX3; paired box gene 3; paired box protein Pax-3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PAX3 (paired box 3)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Pax3 (paired box 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Pax3 (paired box 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PAX3 (paired box 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PAX3 (paired box 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Pax3 (paired box 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PAX3 (paired box 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PAX3 (paired box 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Pax3 (paired box 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Pax3 (paired box 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	PAX7 (paired box 7)	HGNC	OrthoDB
Homo sapiens (human):	FBXW4 (F-box and WD repeat domain containing 4)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	PAX3 (paired box 3)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Pax3 (paired box 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	pax3a (paired box 3a)	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	pax3a (paired box 3a)	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	pax3b (paired box 3b)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	pax-3	Alliance	DIOPT (OrthoFinder\|PANTHER)
Caenorhabditis elegans (roundworm):	pax-3	Alliance	DIOPT (OrthoFinder\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	gsb	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	gsb	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	gsb-n	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	gsb-n	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	prd	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	pax3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	87,015,960 - 87,112,531 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	9	87,016,999 - 87,124,141 (-)	Ensembl				GRCr8
mRatBN7.2	9	79,567,455 - 79,664,042 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	79,568,634 - 79,664,042 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	9	87,998,443 - 88,093,830 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	93,111,318 - 93,206,669 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	91,509,872 - 91,605,274 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	84,004,004 - 84,101,226 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	84,005,183 - 84,101,172 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	9	83,765,158 - 83,871,411 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	9	77,477,813 - 77,576,632 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	9	77,080,699 - 77,176,237 (-)	NCBI		Celera
RGSC_v3.1	9	77,692,768 - 77,692,881 (-)	NCBI
Cytogenetic Map	9	q33	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

alveolar rhabdomyosarcoma (ISO)

brain stem glioma (ISO)

congenital diaphragmatic hernia (ISO)

Congenital Hand Deformities (ISO)

Craniofacial Abnormalities (ISO)

craniofacial-deafness-hand syndrome (ISO)

Deafness (ISO)

Desbuquois dysplasia (ISO)

Diaphragmatic Hernia (IEP)

genetic disease (ISO)

Hearing Loss (ISO)

intellectual disability (ISO)

Nervous System Malformations (ISO)

neural tube defect (ISO,ISS)

Neurodevelopmental Disorders (ISO)

sarcoma (ISO)

sinonasal undifferentiated carcinoma (ISO)

spina bifida (ISO)

Usher syndrome (ISO)

Waardenburg syndrome (ISO)

Waardenburg syndrome type 1 (ISO,ISS)

Waardenburg syndrome type 3 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(R,R,R)-alpha-tocopherol (ISO)

(S)-nicotine (EXP)

1,2-dichloroethane (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-di-tert-butylphenol (ISO)

4,4'-sulfonyldiphenol (ISO)

5-bromo-2'-deoxyuridine (ISO)

5-fluorouracil (ISO)

6-propyl-2-thiouracil (EXP)

abacavir (ISO)

aflatoxin B1 (ISO)

aldehydo-D-glucose (EXP,ISO)

all-trans-retinoic acid (ISO)

all-trans-retinol (EXP)

amiodarone (ISO)

amitrole (EXP)

ammonium chloride (EXP)

ANTIMYCIN (ISO)

arsenite(3-) (ISO)

arsenous acid (ISO)

belinostat (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

bromobenzene (EXP)

Butylbenzyl phthalate (ISO)

cadmium atom (ISO)

cadmium sulfate (ISO)

caffeine (ISO)

CGP 52608 (ISO)

CHIR 99021 (ISO)

choline (ISO)

copper(II) sulfate (ISO)

cycloheximide (ISO)

D-glucose (EXP,ISO)

dabigatran (ISO)

dexamethasone (ISO)

diarsenic trioxide (ISO)

dimethylarsinic acid (EXP)

dorsomorphin (ISO)

endosulfan (EXP)

entinostat (ISO)

ethylene glycol (ISO)

fluoxetine (ISO)

folic acid (ISO)

FR900359 (ISO)

furan (EXP)

gentamycin (EXP)

glucose (EXP,ISO)

Glutathione ethyl ester (ISO)

glycolic acid (ISO)

glyphosate (ISO)

L-methionine (ISO)

lipopolysaccharide (ISO)

lithium chloride (ISO)

methimazole (EXP)

methylmercury chloride (ISO)

methylparaben (ISO)

mono(2-ethylhexyl) phthalate (ISO)

N,N-diethyl-m-toluamide (EXP)

N-ethyl-N-nitrosourea (ISO)

nicotine (EXP)

nilotinib (ISO)

nitrofen (EXP)

panobinostat (ISO)

permethrin (EXP)

phenylmercury acetate (ISO)

phenytoin (ISO)

propanal (ISO)

propiconazole (EXP)

Ptaquiloside (ISO)

resveratrol (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

stilbenoid (ISO)

streptomycin (ISO)

sunitinib (ISO)

thalidomide (ISO)

Theaflavin 3,3'-digallate (ISO)

titanium dioxide (ISO)

trichostatin A (ISO)

valproic acid (ISO)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

anatomical structure morphogenesis (IEA)

animal organ development (IEA)

cell migration (ISO)

cell population proliferation (ISO)

developmental pigmentation (ISO)

gliogenesis (NAS)

heart development (ISO)

mammary gland specification (ISO)

muscle organ development (IEA,ISO)

negative regulation of transcription by RNA polymerase II (ISO)

nervous system development (IBA,IEA)

neural crest cell migration (ISO)

neural tube closure (ISO)

neural tube development (IEA,ISO)

neuron fate commitment (IEA,ISO)

positive regulation of cell population proliferation (IEA,ISO)

positive regulation of DNA-templated transcription (ISO)

positive regulation of transcription by RNA polymerase II (ISO)

regulation of DNA-templated transcription (IEA)

regulation of somitogenesis (ISO)

regulation of transcription by RNA polymerase II (IBA,IEA)

skeletal muscle organ development (IEA,ISO)

spinal cord association neuron differentiation (IEA,ISO)

tissue morphogenesis (IEA)

Cellular Component

nucleoplasm (ISO)

nucleus (IEA,ISO)

Molecular Function

chromatin binding (ISO)

DNA binding (IEA)

DNA-binding transcription factor activity (NAS)

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA,IEA,ISO)

HMG box domain binding (IPI)

protein binding (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IBA)

sequence-specific DNA binding (ISO)

sequence-specific double-stranded DNA binding (ISO)

transcription coregulator binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Pax3 mRNA is decreased in the hearts of rats with experimental diaphragmatic hernia.	Gonzalez-Reyes S, etal., Pediatr Surg Int. 2005 Mar;21(3):203-7. Epub 2004 Dec 23.
3.	Sox10, a novel transcriptional modulator in glial cells.	Kuhlbrodt K, etal., J Neurosci 1998 Jan 1;18(1):237-50.
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	Pax3 expression enhances PDGF-B-induced brainstem gliomagenesis and characterizes a subset of brainstem glioma.	Misuraca KL, etal., Acta Neuropathol Commun. 2014 Oct 21;2:134. doi: 10.1186/s40478-014-0134-6.
6.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
7.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
8.	GOA pipeline	RGD automated data pipeline
9.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
11.	The mutational spectrum in Waardenburg syndrome.	Tassabehji M, etal., Hum Mol Genet. 1995 Nov;4(11):2131-7.
12.	Gene expression signatures identify rhabdomyosarcoma subtypes and detect a novel t(2;2)(q35;p23) translocation fusing PAX3 to NCOA1.	Wachtel M, etal., Cancer Res. 2004 Aug 15;64(16):5539-45.
13.	The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors.	Wissmuller S, etal., Nucleic Acids Res. 2006 Mar 31;34(6):1735-44. Print 2006.
14.	Homozygous and heterozygous inheritance of PAX3 mutations causes different types of Waardenburg syndrome.	Wollnik B, etal., Am J Med Genet A. 2003 Sep 15;122(1):42-5.

Additional References at PubMed

PMID:9858722	PMID:10231856	PMID:10419687	PMID:10946068	PMID:11863357	PMID:15132998	PMID:15322542	PMID:15384171	PMID:15729346	PMID:16300735	PMID:16720875	PMID:17974128
PMID:18508329	PMID:19101644	PMID:21177767	PMID:21371476	PMID:22532290	PMID:22703771	PMID:24443808	PMID:28223217	PMID:29134414

Genomics

Comparative Map Data

Pax3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	87,015,960 - 87,112,531 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	9	87,016,999 - 87,124,141 (-)	Ensembl				GRCr8
mRatBN7.2	9	79,567,455 - 79,664,042 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	79,568,634 - 79,664,042 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	9	87,998,443 - 88,093,830 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	93,111,318 - 93,206,669 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	91,509,872 - 91,605,274 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	84,004,004 - 84,101,226 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	84,005,183 - 84,101,172 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	9	83,765,158 - 83,871,411 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	9	77,477,813 - 77,576,632 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	9	77,080,699 - 77,176,237 (-)	NCBI		Celera
RGSC_v3.1	9	77,692,768 - 77,692,881 (-)	NCBI
Cytogenetic Map	9	q33	NCBI

PAX3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	222,199,887 - 222,298,998 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	222,199,887 - 222,298,998 (-)	Ensembl			hg38	GRCh38
GRCh37	2	223,064,606 - 223,163,717 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	222,772,851 - 222,871,944 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	2	222,891,555 - 222,989,205	NCBI
Celera	2	216,832,726 - 216,931,738 (-)	NCBI		Celera
Cytogenetic Map	2	q36.1	NCBI
HuRef	2	214,918,697 - 215,017,780 (-)	NCBI		HuRef
CHM1_1	2	223,071,095 - 223,170,215 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	2	222,684,993 - 222,784,124 (-)	NCBI		T2T-CHM13v2.0

Pax3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	78,077,904 - 78,173,773 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	78,077,904 - 78,173,771 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	1	78,101,267 - 78,197,136 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	78,101,267 - 78,197,134 (-)	Ensembl			mm10	GRCm38
MGSCv37	1	78,097,842 - 78,193,711 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	1	77,985,839 - 78,080,283 (-)	NCBI		MGSCv36	mm8
Celera	1	78,585,057 - 78,620,745 (-)	NCBI		Celera
Cytogenetic Map	1	C4	NCBI
cM Map	1	39.79	NCBI

Pax3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955453	11,463,379 - 11,558,006 (+)	Ensembl
ChiLan1.0	NW_004955453	11,463,407 - 11,558,001 (+)	NCBI	ChiLan1.0	ChiLan1.0

PAX3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	13	124,814,872 - 124,914,320 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2B	124,829,836 - 124,951,447 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2B	109,441,938 - 109,541,449 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2B	228,022,453 - 228,121,850 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	228,022,453 - 228,121,874 (-)	Ensembl			panPan2	panpan1.1

PAX3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	37	28,346,476 - 28,443,648 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	37	28,346,563 - 28,444,561 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	37	29,183,832 - 29,282,546 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	37	28,371,451 - 28,469,641 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	37	28,371,535 - 28,469,658 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	37	28,283,899 - 28,382,350 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	37	28,214,748 - 28,313,220 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	37	28,233,000 - 28,331,742 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0
Dog Cytomap	37	q16-q17	NCBI

Pax3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	177,872,678 - 177,964,983 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936569	4,216,900 - 4,307,815 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936569	4,215,513 - 4,307,815 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PAX3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	124,094,295 - 124,193,011 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	15	124,093,803 - 124,193,041 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

PAX3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	108,125,198 - 108,225,217 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	10	108,125,747 - 108,224,478 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666040	91,149,850 - 91,250,433 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Pax3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624823	2,871,162 - 2,961,944 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624823	2,870,762 - 2,963,134 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Pax3
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	4	151,317,944 - 151,412,926 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Pax3
755 total Variants

miRNA Target Status (No longer updated)

Confirmed Target Of

miRNA Gene	Mature miRNA	Method Name	Result Type	Data Type	Support Type	PMID
Mir1	rno-miR-1-3p	Mirtarbase	external_info	Luciferase reporter assay	Functional MTI	21730146
Mir206	rno-miR-206-3p	Mirtarbase	external_info	Luciferase reporter assay	Functional MTI	21730146

Predicted Target Of

	Summary Value
Count of predictions:	78
Count of miRNA genes:	60
Interacting mature miRNAs:	75
Transcripts:	ENSRNOT00000018652
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631656	Bp108	Blood pressure QTL 108	5.97	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	56047863	101047863	Rat
1582203	Gluco19	Glucose level QTL 19	3.3	0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	9	63376862	108376862	Rat
8662828	Vetf6	Vascular elastic tissue fragility QTL 6	3.9		artery integrity trait (VT:0010639)	patent ductus arteriosus score (CMO:0002566)	9	44458256	99506504	Rat
724515	Uae16	Urinary albumin excretion QTL 16	8		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	65657365	108376720	Rat
724547	Cm21	Cardiac mass QTL 21	2.7		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	9	86720043	110356905	Rat
2303178	Bp334	Blood pressure QTL 334	3.7	0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	86720043	121768150	Rat
724544	Uae9	Urinary albumin excretion QTL 9	4.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	9	64220169	109220169	Rat
6903941	Pur31	Proteinuria QTL 31		0.036	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	9	86722132	92642305	Rat
2290450	Scl57	Serum cholesterol level QTL 57	4.15		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	9	44458256	121768150	Rat
1578760	Cm53	Cardiac mass QTL 53	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	9	64220169	109220169	Rat
1581580	Uae34	Urinary albumin excretion QTL 34			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	64220169	109220169	Rat
1300134	Bp185	Blood pressure QTL 185	3.73		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	9	68875497	121768150	Rat
1354626	Bvd1	Brain ventricular dilatation QTL 1	3.73	0.001	brain ventricle morphology trait (VT:0000822)	hydrocephalus severity score (CMO:0001881)	9	83161999	118999486	Rat
4889852	Pur26	Proteinuria QTL 26	15	0.001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	9	85262459	109044727	Rat
7794784	Mcs31	Mammary carcinoma susceptibility QTL 31	2.98		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	9	85262459	118999486	Rat
731164	Uae25	Urinary albumin excretion QTL 25	3.5	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	48718864	108376862	Rat
4889943	Bss90	Bone structure and strength QTL 90	4.1		tibia area (VT:1000281)	tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)	9	54506504	99506504	Rat
1578757	Pur6	Proteinuria QTL 6	3.3	0.005	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	9	64220169	109220169	Rat

Markers in Region

X59358

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	79,569,298 - 79,569,447 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	84,005,848 - 84,005,996	NCBI	Rnor6.0
Rnor_5.0	9	83,767,002 - 83,767,150	UniSTS	Rnor5.0
RGSC_v3.4	9	77,478,478 - 77,478,626	UniSTS	RGSC3.4
Celera	9	77,081,364 - 77,081,512	UniSTS
Cytogenetic Map	9	q33	UniSTS

RH142754

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	79,647,711 - 79,647,865 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	84,084,433 - 84,084,586	NCBI	Rnor6.0
Rnor_5.0	9	83,845,657 - 83,845,810	UniSTS	Rnor5.0
RGSC_v3.4	9	77,559,803 - 77,559,956	UniSTS	RGSC3.4
Celera	9	77,160,102 - 77,160,255	UniSTS
RH 3.4 Map	9	734.1	UniSTS
Cytogenetic Map	9	q33	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
6	11	11	104	37	36	13	14	13	6	82	49	5	90	6	62	23	1	1

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_053710	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006245131	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008767181	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF390074	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY169320	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000018652 ⟹ ENSRNOP00000018652

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	9	87,017,137 - 87,112,531 (-)	Ensembl
mRatBN7.2 Ensembl	9	79,568,634 - 79,664,042 (-)	Ensembl
Rnor_6.0 Ensembl	9	84,005,183 - 84,101,172 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000102177 ⟹ ENSRNOP00000095553

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	9	87,016,999 - 87,112,531 (-)	Ensembl
mRatBN7.2 Ensembl	9	79,569,121 - 79,664,042 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000138693 ⟹ ENSRNOP00000111896

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	9	87,017,137 - 87,124,141 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000169996 ⟹ ENSRNOP00000109155

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	9	87,016,999 - 87,112,531 (-)	Ensembl

RefSeq Acc Id:

NM_053710 ⟹ NP_446162

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	87,017,137 - 87,112,531 (-)	NCBI
mRatBN7.2	9	79,568,634 - 79,664,042 (-)	NCBI
Rnor_6.0	9	84,005,183 - 84,101,172 (-)	NCBI
Rnor_5.0	9	83,765,158 - 83,871,411 (-)	NCBI
RGSC_v3.4	9	77,477,813 - 77,576,632 (-)	RGD
Celera	9	77,080,699 - 77,176,237 (-)	RGD

Sequence:

show sequence

TCCCTCGTCGGGATCCCTGCACTCCGTGTCAAGGCGGGAGGAGACTTGGGACGTACTCCTGCCT
CGTCACCACCCTCCCTCCCCCGATCTTCGCGGTGCCTTGAGCACCTTTGCCAGTGGCCCCAGCT
GAGGGGCCGATCTGCTAGACTCGCACCAAACTTGTCCGCCCTGGGCTTGGGATCCTGCACTCAA
GGGACTCCTCTGGAGCCAGTGGACTTGGAGCTATTAGCGCCCCCTCCCCGCGCCCCGCCTCCCT
CTCCTGCCTTTTTTTGGGGAGGAGCTCTCCGCGATCCGGAGAGTTCCCGAGGGTCACCCGCCGC
ACTGTGCTCGCTTTTCCGTCTCGCCTTCACCTGGATATAATTTGCCAGCGAAGCTGCCCCCAGG
ATGACCACGCTGGCCGGCGCTGTGCCCAGGATGATGCGGCCCGGCCCGGGGCAGAATTACCCAC
GCAGCGGCTTCCCACTGGAAGTGTCTACACCCCTCGGCCAGGGCCGAGTCAATCAGCTCGGAGG
AGTATTTATCAACGGCAGGCCTCTGCCCAACCACATCCGCCACAAGATCGTGGAGATGGCCCAC
CACGGCATTCGGCCTTGCGTCATCTCTCGCCAACTTCGCGTGTCCCACGGCTGTGTCTCTAAGA
TCTTATGCAGGTACCAGGAGACAGGCTCCATCCGACCTGGCGCCATTGGCGGCAGCAAGCCCAA
GCAGGTGACAACGCCTGACGTGGAGAAGAAAATTGAGGAATACAAAAGAGAGAACCCAGGCATG
TTTAGCTGGGAAATCAGAGACAAATTACTCAAGGACGCTGTCTGTGATCGGAACACTGTGCCCT
CAGTGAGTTCCATCAGTCGCATCCTGAGGAGTAAATTTGGAAAAGGAGAAGAGGAGGAGGCGGA
TTTAGAAAGGAAAGAAGCCGAGGAAAGCGAGAAAAAGGCTAAACACAGCATCGATGGCATCCTA
AGTGAGCGAGCCTCCGCACCTCAATCAGATGAAGGCTCGGACATTGACTCAGAACCTGATTTAC
CGCTGAAGAGGAAGCAGCGCAGGAGTAGAACCACCTTCACCGCAGAGCAGCTGGAGGAACTGGA
GCGCGCTTTCGAGAGAACCCACTATCCAGACATTTACACCAGGGAGGAGCTGGCCCAGAGGGCG
AAGCTTACTGAGGCCCGAGTGCAGGTCTGGTTTAGCAACCGCCGTGCAAGATGGAGGAAGCAAG
CTGGAGCCAATCAACTGATGGCTTTCAACCATCTCATTCCGGGGGGATTCCCTCCCACCGCCAT
GCCGACCCTGCCAACATACCAGCTGTCGGAGACCTCTTACCAGCCCACGTCTATTCCACAAGCC
GTATCAGATCCCAGTAGTACTGTTCACAGACCTCAGCCGCTTCCTCCGAGCACTGTCCACCAAA
GCACCATTCCTTCGAATGCAGACAGCAGCTCTGCCTACTGCCTTCCCAGCACCAGGCATGGATT
TTCAAGCTACACCGACAGCTTCGTGCCTCCATCGGGGCCCTCCAACCCCATGAACCCCGCCATT
GGCAATGGCCTTTCACCTCAGGTAATGGGACTTCTGACCAACCACGGTGGGGTACCGCACCAGC
CTCAGACCGACTATGCTCTCTCCCCTCTCACTGGGGGCCTGGAACCCACGACCACGGTGTCAGC
CAGCTGCAGTCAGAGATTGGAGCACATGAAGAATGTGGACAGTCTGCCCACATCTCAGCCCTAC
TGTCCCCCCACCTATAGTACCACAGGCTACAGCATGGACCCTGTCACGGGCTACCAGTATGGGC
AGTATGGACAAAGTGCCTTTCATTATCTCAAGCCAGATATTGCATAAGTGAACTGTCCACATGG
AGCCCTGTTTCCGGCCTCCACAGACTAGACATGAAGAATCTTCTCAGAAACAAAACATAACAAA
ACAATAATAATAAAAAAATAATAAATTTTAAAAAAATCAGCTTTTGGGGGAGGTGGAGACGAAA
GAAAGCGATTGATTTTCTTTCTCCAGTAGTTGCTTTCAGACTCTTTGAACAAAAAACAGGGGAG
GCAAGGAAGACCCAGAGCTATAAAACGCACCATTTTAAGACAGTGACGTAACCTGGCTACATAT
CAAAAATGTCCCCAACTCTTTGTTGCTGATCAAGAAGCTAAAACATTCCATGTGTGTGTGTGTG
TGTGTGTGTGTGTGTGTGTGA

hide sequence

RefSeq Acc Id:

XM_006245131 ⟹ XP_006245193

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	87,015,960 - 87,112,506 (-)	NCBI
mRatBN7.2	9	79,567,455 - 79,664,002 (-)	NCBI
Rnor_6.0	9	84,004,004 - 84,101,226 (-)	NCBI
Rnor_5.0	9	83,765,158 - 83,871,411 (-)	NCBI

Sequence:

show sequence

CAATCGCAGCTCAGGGCTCCTGATCTAGCTTTGGGTGAAAGAACTAATAAATGCTCCCTCGTCG
GGATCCCTGCACTCCGTGTCAAGGCGGGAGGAGACTTGGGACGTACTCCTGCCTCGTCACCACC
CTCCCTCCCCCGATCTTCGCGGTGCCTTGAGCACCTTTGCCAGTGGCCCCAGCTGAGGGGCCGA
TCTGCTAGACTCGCACCAAACTTGTCCGCCCTGGGCTTGGGATCCTGCACTCAAGGGACTCCTC
TGGAGCCAGTGGACTTGGAGCTATTAGCGCCCCCTCCCCGCGCCCCGCCTCCCTCTCCTGCCTT
TTTTTGGGGAGGAGCTCTCCGCGATCCGGAGAGTTCCCGAGGGTCACCCGCCGCACTGTGCTCG
CTTTTCCGTCTCGCCTTCACCTGGATATAATTTGCCAGCGAAGCTGCCCCCAGGATGACCACGC
TGGCCGGCGCTGTGCCCAGGATGATGCGGCCCGGCCCGGGGCAGAATTACCCACGCAGCGGCTT
CCCACTGGAAGTGTCTACACCCCTCGGCCAGGGCCGAGTCAATCAGCTCGGAGGAGTATTTATC
AACGGCAGGCCTCTGCCCAACCACATCCGCCACAAGATCGTGGAGATGGCCCACCACGGCATTC
GGCCTTGCGTCATCTCTCGCCAACTTCGCGTGTCCCACGGCTGTGTCTCTAAGATCTTATGCAG
GTACCAGGAGACAGGCTCCATCCGACCTGGCGCCATTGGCGGCAGCAAGCCCAAGGTGACAACG
CCTGACGTGGAGAAGAAAATTGAGGAATACAAAAGAGAGAACCCAGGCATGTTTAGCTGGGAAA
TCAGAGACAAATTACTCAAGGACGCTGTCTGTGATCGGAACACTGTGCCCTCAGTGAGTTCCAT
CAGTCGCATCCTGAGGAGTAAATTTGGAAAAGGAGAAGAGGAGGAGGCGGATTTAGAAAGGAAA
GAAGCCGAGGAAAGCGAGAAAAAGGCTAAACACAGCATCGATGGCATCCTAAGTGAGCGAGCCT
CCGCACCTCAATCAGATGAAGGCTCGGACATTGACTCAGAACCTGATTTACCGCTGAAGAGGAA
GCAGCGCAGGAGTAGAACCACCTTCACCGCAGAGCAGCTGGAGGAACTGGAGCGCGCTTTCGAG
AGAACCCACTATCCAGACATTTACACCAGGGAGGAGCTGGCCCAGAGGGCGAAGCTTACTGAGG
CCCGAGTGCAGGTCTGGTTTAGCAACCGCCGTGCAAGATGGAGGAAGCAAGCTGGAGCCAATCA
ACTGATGGCTTTCAACCATCTCATTCCGGGGGGATTCCCTCCCACCGCCATGCCGACCCTGCCA
ACATACCAGCTGTCGGAGACCTCTTACCAGCCCACGTCTATTCCACAAGCCGTATCAGATCCCA
GTAGTACTGTTCACAGACCTCAGCCGCTTCCTCCGAGCACTGTCCACCAAAGCACCATTCCTTC
GAATGCAGACAGCAGCTCTGCCTACTGCCTTCCCAGCACCAGGCATGGATTTTCAAGCTACACC
GACAGCTTCGTGCCTCCATCGGGGCCCTCCAACCCCATGAACCCCGCCATTGGCAATGGCCTTT
CACCTCAGGTAATGGGACTTCTGACCAACCACGGTGGGGTACCGCACCAGCCTCAGACCGACTA
TGCTCTCTCCCCTCTCACTGGGGGCCTGGAACCCACGACCACGGTGTCAGCCAGCTGCAGTCAG
AGATTGGAGCACATGAAGAATGTGGACAGTCTGCCCACATCTCAGCCCTACTGTCCCCCCACCT
ATAGTACCACAGGCTACAGCATGGACCCTGTCACGGGCTACCAGTATGGGCAGTATGGACAAAG
TGCCTTTCATTATCTCAAGCCAGATATTGCATAAGTGAACTGTCCACATGGAGCCCTGTTTCCG
GCCTCCACAGACTAGACATGAAGAATCTTCTCAGAAACAAAACATAACAAAACAATAATAATAA
AAAAATAATAAATTTTAAAAAAATCAGCTTTTGGGGGAGGTGGAGACGAAAGAAAGCGATTGAT
TTTCTTTCTCCAGTAGTTGCTTTCAGACTCTTTGAACAAAAAACAGGGGAGGCAAGGAAGACCC
AGAGCTATAAAACGCACCATTTTAAGACAGTGACGTAACCTGGCTACATATCAAAAATGTCCCC
AACTCTTTGTTGCTGATCAAGAAGCTAAAACATTCCATGTGTGTGTGTGTGTGTGTGTGTGTGT
GTGTGTGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGTTTCATA
GGCTGGTTTGAATAAGCATAATGTTCCCATATATTGTAATTGAATTCTTGAAAGTTAACAGGTT
TGATGTCTAAGGCTGACCAAGTTTGTGACATTCACACTGCTTACATAATGAATTGGAAGTGGAG
GAATCCTTGACTTTGACACACTGGAAACTGATCTGAAAACCAACACCACCATTTTACAGGATGC
TAGACTAGACGTGAAGGATCTCCCCAATAAATAATTGTCATACCTTCATTCATAACCTAGTTGC
CAACCGATGTCCCTGACATGTCTTGTAAAAAGATAGTGAGAAAAAGTGTGTTATCTGCTGTGGG
GATAGATGGATGTCATCCACTTCCCAAGTCACATTGATTTGGAAGCCAGCCTGGGTGGGGGGAA
GGGCATGACCGAGAGGAAGTGACACCCATCACATAATCTGCTTTTCAGCGTGCAATACTGTGTA
CCTCACAGATGCTTTGGCCATGGCCAAGGCGATAGAAATGGAATCAGAACTATATTTTTGCAGG
TGTTTTTATTTTTGCAGCCCATAACCCATCGTTGTAGAATGCAGTGATGTTTTCGAGTTACTAA
ACAACCCACATCCTGCTTGCTCTTTTTGCTCAGAGACTCTGTCTGAGAATGAAGCTTTCTACAG
CAGTGACGTTTACATTCTCGTCTCTTTTCTACGAAAGGCAGGGCTTGAGCAGAAATGTCCACGT
GGCTCTCGTGTACTTTTAAATTATACAGTGATACCCAATATTAAAGGATGGTAGGGAACAGAGG
TTTACATGCATTTATGCGGTGACATTTAGGATGTCAATAAATCTGTGTTTTGAAATGTTAAGAG
GAAGATGAAGGTGGGCGGTGCTGTTATTTATTTCTTTCTATTCTTGGAACCATGAATGAGGTAG
ACACAAATACATTCCCTTTAGATGTAAGAACAATGAGGTAGTGTGTTAGCAGGACTAGACATAG
AACTGAGTTATTTTATACGTTGGACAAGGGTGATGAAACAGGAGACATAGTATCTCTGTGTTGC
AGCCTCAACCAACAATGATGTGTTGTAAAAATGTCTTTCATGTAAAAAGTGCAGTAAATATTTA
CTATTTATAATGAATAAACAGTTAATGAAAACGTG

hide sequence

Protein Sequences


Protein RefSeqs	NP_446162	(Get FASTA)	NCBI Sequence Viewer
	XP_006245193	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAK70501	(Get FASTA)	NCBI Sequence Viewer
	AAO17711	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000018652
	ENSRNOP00000018652.5
	ENSRNOP00000095553.1
	ENSRNOP00000109155.1
	ENSRNOP00000111896.1

RefSeq Acc Id:

NP_446162 ⟸ NM_053710

- UniProtKB:

F1LMV3 (UniProtKB/TrEMBL), A0A8I6ATQ4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAH
HGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGM
FSWEIRDKLLKDAVCDRNTVPSVSSISRILRSKFGKGEEEEADLERKEAEESEKKAKHSIDGIL
SERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRA
KLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTSIPQA
VSDPSSTVHRPQPLPPSTVHQSTIPSNADSSSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNPAI
GNGLSPQVMGLLTNHGGVPHQPQTDYALSPLTGGLEPTTTVSASCSQRLEHMKNVDSLPTSQPY
CPPTYSTTGYSMDPVTGYQYGQYGQSAFHYLKPDIA

hide sequence

RefSeq Acc Id:	XP_006245193 ⟸ XM_006245131
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6ATQ4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAH HGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKVTTPDVEKKIEEYKRENPGMF SWEIRDKLLKDAVCDRNTVPSVSSISRILRSKFGKGEEEEADLERKEAEESEKKAKHSIDGILS ERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAK LTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTSIPQAV SDPSSTVHRPQPLPPSTVHQSTIPSNADSSSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNPAIG NGLSPQVMGLLTNHGGVPHQPQTDYALSPLTGGLEPTTTVSASCSQRLEHMKNVDSLPTSQPYC PPTYSTTGYSMDPVTGYQYGQYGQSAFHYLKPDIA hide sequence

Ensembl Acc Id:

ENSRNOP00000018652 ⟸ ENSRNOT00000018652

Ensembl Acc Id:

ENSRNOP00000095553 ⟸ ENSRNOT00000102177

Ensembl Acc Id:

ENSRNOP00000109155 ⟸ ENSRNOT00000169996

Ensembl Acc Id:

ENSRNOP00000111896 ⟸ ENSRNOT00000138693

Protein Domains

Homeobox Paired

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1LMV3-F1-model_v2	AlphaFold	F1LMV3	1-484	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620431	AgrOrtholog
BioCyc Gene	G2FUF-27029	BioCyc
Ensembl Genes	ENSRNOG00000013670	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000018652	ENTREZGENE
	ENSRNOT00000018652.7	UniProtKB/TrEMBL
	ENSRNOT00000102177.2	UniProtKB/TrEMBL
	ENSRNOT00000138693.1	UniProtKB/TrEMBL
	ENSRNOT00000169996.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.10.10	UniProtKB/TrEMBL
	Homeodomain-like	UniProtKB/TrEMBL
InterPro	Homeobox_CS	UniProtKB/TrEMBL
	Homeodomain	UniProtKB/TrEMBL
	Homeodomain-like	UniProtKB/TrEMBL
	PAIRED_DNA_bd_dom	UniProtKB/TrEMBL
	Paired_dom	UniProtKB/TrEMBL
	Paired_Homeobox_TFs	UniProtKB/TrEMBL
	Pax7	UniProtKB/TrEMBL
	PAX_fam	UniProtKB/TrEMBL
	WH-like_DNA-bd_sf	UniProtKB/TrEMBL
KEGG Report	rno:114502	UniProtKB/TrEMBL
NCBI Gene	114502	ENTREZGENE
PANTHER	DORSAL ROOT GANGLIA HOMEOBOX, ISOFORM E-RELATED	UniProtKB/TrEMBL
	HOMEOBOX PROTEIN ARISTALESS	UniProtKB/TrEMBL
	PAIRED BOX PROTEIN PAX-3	UniProtKB/TrEMBL
	PTHR45636	UniProtKB/TrEMBL
Pfam	Homeobox	UniProtKB/TrEMBL
	PAX	UniProtKB/TrEMBL
	Pax7	UniProtKB/TrEMBL
PhenoGen	Pax3	PhenoGen
PRINTS	PAIREDBOX	UniProtKB/TrEMBL
PROSITE	HOMEOBOX_1	UniProtKB/TrEMBL
	HOMEOBOX_2	UniProtKB/TrEMBL
	PAIRED_1	UniProtKB/TrEMBL
	PAIRED_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000013670	RatGTEx
SMART	HOX	UniProtKB/TrEMBL
	PAX	UniProtKB/TrEMBL
Superfamily-SCOP	Homeodomain_like	UniProtKB/TrEMBL
UniProt	A0A8I6ATQ4	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0LZH1_RAT	UniProtKB/TrEMBL
	A0ABK0M232_RAT	UniProtKB/TrEMBL
	F1LMV3	ENTREZGENE, UniProtKB/TrEMBL
	Q91XM5_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-10-30	Pax3	paired box 3	Pax3	paired box gene 3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-20	Pax3	paired box gene 3			Symbol and Name status set to approved	1299863	APPROVED
2002-08-07	Pax3	paired box gene 3			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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