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Gene: Pafah1b2 (platelet-activating factor acetylhydrolase 1b, catalytic subunit 2) Rattus norvegicus

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Symbol:

Pafah1b2

Name:

platelet-activating factor acetylhydrolase 1b, catalytic subunit 2

RGD ID:

620332

Description:

Enables 1-alkyl-2-acetylglycerophosphocholine esterase activity; identical protein binding activity; and platelet-activating factor acetyltransferase activity. Predicted to be involved in positive regulation of macroautophagy and spermatogenesis. Part of 1-alkyl-2-acetylglycerophosphocholine esterase complex. Biomarker of status epilepticus. Human ortholog(s) of this gene implicated in lymphoma. Orthologous to human PAFAH1B2 (platelet activating factor acetylhydrolase 1b catalytic subunit 2); PARTICIPATES IN altered Reelin signaling pathway; Reelin signaling pathway; ether lipid metabolic pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

MGC93124; PAF acetylhydrolase 30 kDa subunit; PAF-AH 30 kDa subunit; PAF-AH alpha 2; PAF-AH subunit beta; PAFAH subunit beta; platelet-activating factor acetylhydrolase alpha 2 subunit (PAF-AH alpha 2); platelet-activating factor acetylhydrolase IB subunit alpha2; platelet-activating factor acetylhydrolase IB subunit beta; platelet-activating factor acetylhydrolase, isoform 1b, alpha2 subunit; platelet-activating factor acetylhydrolase, isoform 1b, subunit 2; platelet-activating factor acetylhydrolase, isoform Ib, beta subunit; platelet-activating factor acetylhydrolase, isoform Ib, subunit 2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	55,156,778 - 55,208,800 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	8	55,156,779 - 55,176,836 (-)	Ensembl				GRCr8
mRatBN7.2	8	46,260,069 - 46,312,073 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	46,261,064 - 46,279,833 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	8	51,761,686 - 51,780,128 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	50,040,454 - 50,058,896 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	47,904,724 - 47,923,167 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	50,256,969 - 50,310,043 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	50,259,248 - 50,277,797 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	8	48,883,712 - 48,934,692 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	8	48,938,556 - 48,957,109 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	8	45,843,851 - 45,862,380 (-)	NCBI		Celera
RGSC_v3.1	8	48,947,322 - 48,965,875 (-)	NCBI
Cytogenetic Map	8	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

lymphoma (ISO)

status epilepticus (IEP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,6-dinitrotoluene (EXP)

4,4'-sulfonyldiphenol (EXP,ISO)

6-propyl-2-thiouracil (EXP)

acrolein (ISO)

actinomycin D (ISO)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

alpha-pinene (ISO)

amitrole (EXP)

ammonium chloride (EXP)

Aroclor 1254 (ISO)

arsenite(3-) (ISO)

bisphenol A (EXP,ISO)

Bisphenol B (ISO)

bisphenol F (EXP)

cadmium atom (ISO)

cadmium dichloride (EXP,ISO)

carbon nanotube (ISO)

cisplatin (ISO)

copper(II) sulfate (ISO)

coumarin (ISO)

cypermethrin (EXP)

dioxygen (ISO)

doxorubicin (ISO)

enzyme inhibitor (ISO)

ethanol (ISO)

fipronil (EXP)

flutamide (EXP)

folic acid (ISO)

formaldehyde (ISO)

FR900359 (ISO)

hypochlorous acid (ISO)

ivermectin (ISO)

methimazole (EXP)

methylazoxymethanol (ISO)

minocycline (EXP)

Nutlin-3 (ISO)

ozone (ISO)

paracetamol (ISO)

PCB138 (EXP)

perfluorooctanoic acid (ISO)

phenobarbital (EXP)

phenytoin (ISO)

pirinixic acid (ISO)

SB 431542 (ISO)

sodium arsenate (ISO)

sodium arsenite (EXP,ISO)

sulfadimethoxine (EXP)

T-2 toxin (ISO)

tamoxifen (ISO)

tetrachloromethane (EXP)

thiram (ISO)

titanium dioxide (ISO)

triphenyl phosphate (ISO)

triptonide (ISO)

valproic acid (ISO)

zearalenone (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

lipid catabolic process (IEA)

lipid metabolic process (IEA)

positive regulation of macroautophagy (IEA,ISO)

spermatogenesis (IBA,ISO,ISS)

Cellular Component

1-alkyl-2-acetylglycerophosphocholine esterase complex (IBA,IDA,IEA,ISO,ISS)

cytoplasm (IBA,IEA,ISO)

cytosol (IEA,ISO)

Molecular Function

1-alkyl-2-acetylglycerophosphocholine esterase activity (IBA,IDA,IEA,ISS)

hydrolase activity (IEA)

identical protein binding (IPI)

platelet-activating factor acetyltransferase activity (IBA,IDA,IEA,TAS)

protein binding (IPI,ISO)

protein heterodimerization activity (ISS)

protein homodimerization activity (ISS)

protein-containing complex binding (IPI)

Molecular Pathway Annotations Click to see Annotation Detail View

altered Reelin signaling pathway (ISO)

ether lipid metabolic pathway (IEA)

Reelin signaling pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Platelet-activating factor acetylhydrolase (PAF-AH).	Arai H, etal., J Biochem. 2002 May;131(5):635-40.
2.	Anti-apoptotic actions of the platelet-activating factor acetylhydrolase I alpha2 catalytic subunit.	Bonin F, etal., J Biol Chem 2004 Dec 10;279(50):52425-36. Epub 2004 Sep 28.
3.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	Direct association of LIS1, the lissencephaly gene product, with a mammalian homologue of a fungal nuclear distribution protein, rNUDE.	Kitagawa M, etal., FEBS Lett 2000 Aug 11;479(1-2):57-62.
5.	Switching of platelet-activating factor acetylhydrolase catalytic subunits in developing rat brain.	Manya H, etal., J Biol Chem. 1998 Jul 17;273(29):18567-72.
6.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
7.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
8.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
9.	GOA pipeline	RGD automated data pipeline
10.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
12.	Platelet-activating factor (PAF) acetylhydrolase activity, LIS1 expression, and seizures.	Shmueli O, etal., J Neurosci Res. 1999 Jul 15;57(2):176-84.
13.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
14.	Molecular cloning of cDNAs encoding alpha1, alpha2, and beta subunits of rat brain platelet-activating factor acetylhydrolase.	Watanabe M, etal., Biochim Biophys Acta 1998 Jan 2;1401(1):73-9.
15.	The Pafah1b complex interacts with the reelin receptor VLDLR.	Zhang G, etal., PLoS One. 2007 Feb 28;2(2):e252.

Additional References at PubMed

PMID:12551946	PMID:15489334	PMID:19056867	PMID:22354037	PMID:23376485	PMID:33760887

Genomics

Comparative Map Data

Pafah1b2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	55,156,778 - 55,208,800 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	8	55,156,779 - 55,176,836 (-)	Ensembl				GRCr8
mRatBN7.2	8	46,260,069 - 46,312,073 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	46,261,064 - 46,279,833 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	8	51,761,686 - 51,780,128 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	50,040,454 - 50,058,896 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	47,904,724 - 47,923,167 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	50,256,969 - 50,310,043 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	50,259,248 - 50,277,797 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	8	48,883,712 - 48,934,692 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	8	48,938,556 - 48,957,109 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	8	45,843,851 - 45,862,380 (-)	NCBI		Celera
RGSC_v3.1	8	48,947,322 - 48,965,875 (-)	NCBI
Cytogenetic Map	8	q22	NCBI

PAFAH1B2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	117,144,287 - 117,178,173 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	117,144,284 - 117,176,894 (+)	Ensembl			hg38	GRCh38
GRCh37	11	117,015,003 - 117,048,889 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	116,520,250 - 116,544,024 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	11	116,520,249 - 116,544,024	NCBI
Celera	11	114,172,757 - 114,205,230 (+)	NCBI		Celera
Cytogenetic Map	11	q23.3	NCBI
HuRef	11	112,947,322 - 112,980,405 (+)	NCBI		HuRef
CHM1_1	11	116,899,903 - 116,932,472 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	117,159,595 - 117,193,468 (+)	NCBI		T2T-CHM13v2.0

Pafah1b2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	45,876,609 - 45,923,988 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	45,874,157 - 45,923,988 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	9	45,965,311 - 46,012,690 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	45,962,859 - 46,012,690 (-)	Ensembl			mm10	GRCm38
MGSCv37	9	45,773,394 - 45,792,954 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	9	45,716,306 - 45,735,866 (-)	NCBI		MGSCv36	mm8
Celera	9	43,249,530 - 43,269,004 (-)	NCBI		Celera
Cytogenetic Map	9	A5.2	NCBI

Pafah1b2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955412	18,474,199 - 18,494,082 (+)	Ensembl
ChiLan1.0	NW_004955412	18,471,621 - 18,494,082 (+)	NCBI	ChiLan1.0	ChiLan1.0

PAFAH1B2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	117,844,005 - 117,870,689 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	118,950,015 - 118,976,715 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	111,978,368 - 112,005,064 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	115,911,803 - 115,944,358 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	115,911,803 - 115,944,351 (+)	Ensembl			panPan2	panpan1.1

PAFAH1B2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ROS_Cfam_1.0	5	16,361,852 - 16,392,824 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	16,358,906 - 16,392,810 (-)	Ensembl				ROS_Cfam_1.0 Ensembl

Pafah1b2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	99,469,237 - 99,496,440 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936542	2,390,513 - 2,414,882 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936542	2,390,904 - 2,417,596 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PAFAH1B2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	44,513,461 - 44,536,432 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	9	44,513,114 - 44,534,312 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	49,590,686 - 49,603,905 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PAFAH1B2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	108,514,443 - 108,542,495 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	108,514,172 - 108,544,049 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666043	17,512,255 - 17,540,709 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Pafah1b2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624784	12,583,430 - 12,619,816 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Pafah1b2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	8	40,484,253 - 40,505,591 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Pafah1b2
492 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	89
Count of miRNA genes:	76
Interacting mature miRNAs:	86
Transcripts:	ENSRNOT00000024828
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2313057	Bss76	Bone structure and strength QTL 76	3	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	8	39106258	91341052	Rat
1298065	Scl16	Serum cholesterol level QTL 16	3.8		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	8	39752803	84752803	Rat
2317030	Wbc5	White blood cell count QTL 5	3.21	0.005	leukocyte quantity (VT:0000217)	white blood cell count (CMO:0000027)	8	16994642	61994642	Rat
1554321	Bmd3	Bone mineral density QTL 3	7.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	49849908	118871671	Rat
2313067	Bss77	Bone structure and strength QTL 77	3.1	0.0001	tibia size trait (VT:0100001)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	8	39106258	91341052	Rat
1578769	Uae31	Urinary albumin excretion QTL 31	3.3	0.001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	8	39106363	103375781	Rat
2317032	Ginf2	Gastrointestinal inflammation QTL 2	3.21	0.005	liver integrity trait (VT:0010547)	liver granuloma severity score (CMO:0002157)	8	12964165	57964165	Rat
2301416	Bp315	Blood pressure QTL 315		0.008	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	15952279	60952279	Rat
1298079	Activ2	Activity QTL 2	9.5	0.000001	voluntary movement trait (VT:0003491)	rearing measurement (CMO:0001515)	8	50763951	95763951	Rat
11556286	Cm81	Cardiac mass QTL 81		0.01	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	8	39106258	84106258	Rat
2317036	Livw3	Liver weight QTL 3	2.43	0.01	liver mass (VT:0003402)	liver weight to body weight ratio (CMO:0000633)	8	12964165	57964165	Rat
70161	Bp62	Blood pressure QTL 62	2.9	0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	51589699	99045312	Rat
12880023	Bw184	Body weight QTL 184		0.001	body mass (VT:0001259)	body weight (CMO:0000012)	8	10382540	55382540	Rat
1578765	Klgr1	Kidney lesion grade QTL 1	3.3	0.0001	kidney morphology trait (VT:0002135)	organ lesion measurement (CMO:0000677)	8	39106363	103375781	Rat
5684993	Bmd84	Bone mineral density QTL 84	4.1		tibia mineral mass (VT:1000283)	bone mineral content (CMO:0001554)	8	51589699	58991895	Rat
12880028	Cm103	Cardiac mass QTL 103		0.02	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	8	10382540	55382540	Rat
2317051	Aia18	Adjuvant induced arthritis QTL 18	2.42		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	8	16994642	61994642	Rat
61464	Niddm11	Non-insulin dependent diabetes mellitus QTL 11	3.1	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	8	44477926	89477926	Rat
2317048	Ginf1	Gastrointestinal inflammation QTL 1	3.52	0.005	cecum mucosa thickness (VT:0010234)	enterocolitis severity score (CMO:0002138)	8	12964165	57964165	Rat
1578755	Pur5	Proteinuria QTL 5	3.3	0.0001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	8	39106258	103375958	Rat
12880025	Cm102	Cardiac mass QTL 102		0.044	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	8	10382540	55382540	Rat
2313088	Bss75	Bone structure and strength QTL 75	3.1	0.0001	body length (VT:0001256)	body length, nose to rump (CMO:0000079)	8	39106258	91341052	Rat
1358896	Bp262	Blood pressure QTL 262	2.89		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	35464071	107982864	Rat
2302278	Gluco36	Glucose level QTL 36	4.2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	8	37760859	58991895	Rat
731182	Uae24	Urinary albumin excretion QTL 24	6.4		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	8	47541419	92541419	Rat
12880044	Am9	Aortic mass QTL 9		0.007	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	8	10382540	55382540	Rat
631648	Stl5	Serum triglyceride level QTL 5	4	0.0003	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	8	35464071	71842899	Rat
724514	Uae15	Urinary albumin excretion QTL 15	2.9		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	8	37760859	61459705	Rat
61353	Bp35	Blood pressure QTL 35		0.001	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	8	39106258	84106258	Rat
631842	Inf1	Infertility severity QTL 1	4.1	0.001	seminal gland mass (VT:0010524)	seminal vesicle wet weight (CMO:0001603)	8	31543661	76543661	Rat
737824	Hcar10	Hepatocarcinoma resistance QTL 10	2.9		liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	8	49610204	68373388	Rat
1359033	Bp273	Blood pressure QTL 273			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	39106258	84106258	Rat
1331769	Rf39	Renal function QTL 39	3.871		urine output (VT:0003620)	timed urine volume (CMO:0000260)	8	50763951	107970527	Rat
61358	Bp39	Blood pressure QTL 39	2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	44447837	89447837	Rat
1358906	Bp253	Blood pressure QTL 253	4	0.0004	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	49610204	94610204	Rat
1358907	Cm40	Cardiac mass QTL 40	1.89		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	8	35464071	107982864	Rat
1598824	Memor4	Memory QTL 4	2.5		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	8	17993862	62252873	Rat
1331744	Bp217	Blood pressure QTL 217	3.398		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	39106258	67378345	Rat
2313046	Bss78	Bone structure and strength QTL 78	3.5	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	8	39106258	91341052	Rat
2316950	Scl66	Serum cholesterol level QTL 66	4.1		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	8	39106363	114525825	Rat
1582254	Kidm31	Kidney mass QTL 31	3		kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	8	49245178	94245178	Rat
724540	Uae8	Urinary albumin excretion QTL 8	5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	8	39106258	103375958	Rat
1358892	Kidm26	Kidney mass QTL 26	3.69		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	8	35464071	107982864	Rat
1359021	Bp271	Blood pressure QTL 271	1.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	34125902	55607752	Rat
631216	Stl9	Serum triglyceride level QTL 9	4.71	0.0001	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	8	50763951	67219641	Rat
1582243	Bw66	Body weight QTL 66	3.4	0.0048	body mass (VT:0001259)	body weight (CMO:0000012)	8	49245178	94245178	Rat
61373	Mcs4	Mammary carcinoma susceptibility QTL 4	1.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	8	44475043	89475043	Rat

Markers in Region

D8Got71

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	46,272,970 - 46,273,149 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	50,270,925 - 50,271,103	NCBI	Rnor6.0
Rnor_5.0	8	48,895,573 - 48,895,751	UniSTS	Rnor5.0
RGSC_v3.4	8	48,950,236 - 48,950,415	RGD	RGSC3.4
RGSC_v3.4	8	48,950,237 - 48,950,415	UniSTS	RGSC3.4
Celera	8	45,855,508 - 45,855,686	UniSTS
RGSC_v3.1	8	48,959,002 - 48,959,181	RGD
RH 3.4 Map	8	473.2	UniSTS
RH 3.4 Map	8	473.2	RGD
RH 2.0 Map	8	366.4	RGD
Cytogenetic Map	8	q22	UniSTS

AI747451

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	46,262,304 - 46,262,434 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	50,260,261 - 50,260,390	NCBI	Rnor6.0
Rnor_5.0	8	48,884,909 - 48,885,038	UniSTS	Rnor5.0
RGSC_v3.4	8	48,939,573 - 48,939,702	UniSTS	RGSC3.4
Celera	8	45,844,868 - 45,844,997	UniSTS
Cytogenetic Map	8	q22	UniSTS

Pafah1b2

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	46,262,314 - 46,262,438 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	50,260,271 - 50,260,394	NCBI	Rnor6.0
Rnor_5.0	8	48,884,919 - 48,885,042	UniSTS	Rnor5.0
RGSC_v3.4	8	48,939,583 - 48,939,706	UniSTS	RGSC3.4
Celera	8	45,844,878 - 45,845,001	UniSTS
Cytogenetic Map	8	q22	UniSTS

RH128517

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	46,260,110 - 46,260,316 (+)	MAPPER	mRatBN7.2
mRatBN7.2	8	84,125,219 - 84,125,411 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	90,729,494 - 90,729,685	NCBI	Rnor6.0
Rnor_6.0	8	50,258,067 - 50,258,272	NCBI	Rnor6.0
Rnor_5.0	8	90,252,738 - 90,252,929	UniSTS	Rnor5.0
Rnor_5.0	8	48,882,535 - 48,882,740	UniSTS	Rnor5.0
RGSC_v3.4	8	48,937,379 - 48,937,584	UniSTS	RGSC3.4
RGSC_v3.4	8	88,271,539 - 88,271,730	UniSTS	RGSC3.4
Celera	8	83,781,455 - 83,781,646	UniSTS
Celera	8	45,842,674 - 45,842,879	UniSTS
Cytogenetic Map	8	q22	UniSTS

RH143765

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	46,275,231 - 46,275,474 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	50,273,200 - 50,273,442	NCBI	Rnor6.0
Rnor_5.0	8	48,897,848 - 48,898,090	UniSTS	Rnor5.0
RGSC_v3.4	8	48,952,512 - 48,952,754	UniSTS	RGSC3.4
Celera	8	45,857,783 - 45,858,025	UniSTS
RH 3.4 Map	8	476.2	UniSTS
Cytogenetic Map	8	q22	UniSTS

RH141413

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	84,123,804 - 84,124,002 (+)	MAPPER	mRatBN7.2
mRatBN7.2	8	46,261,553 - 46,261,751 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	50,259,510 - 50,259,707	NCBI	Rnor6.0
Rnor_6.0	8	90,728,079 - 90,728,276	NCBI	Rnor6.0
Rnor_5.0	8	90,251,323 - 90,251,520	UniSTS	Rnor5.0
Rnor_5.0	8	48,883,978 - 48,884,175	UniSTS	Rnor5.0
RGSC_v3.4	8	48,938,822 - 48,939,019	UniSTS	RGSC3.4
RGSC_v3.4	8	88,270,124 - 88,270,321	UniSTS	RGSC3.4
Celera	8	83,780,040 - 83,780,237	UniSTS
Celera	8	45,844,117 - 45,844,314	UniSTS
Cytogenetic Map	8	q22	UniSTS

AI228182

Rat Assembly	Chr	Position (strand)	Source	JBrowse
RH 3.4 Map	8	896.49	UniSTS
Cytogenetic Map	8	q22	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_022387	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006242958	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039082081	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039082082	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063266074	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063266075	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC094040	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC096909	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF016048	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC081714	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473975	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ212439	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000082508 ⟹ ENSRNOP00000068672

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	55,156,779 - 55,176,836 (-)	Ensembl
mRatBN7.2 Ensembl	8	46,261,064 - 46,279,833 (-)	Ensembl
Rnor_6.0 Ensembl	8	50,259,248 - 50,277,797 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000111151 ⟹ ENSRNOP00000091075

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	46,261,954 - 46,279,806 (-)	Ensembl

RefSeq Acc Id:

NM_022387 ⟹ NP_071782

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	55,157,995 - 55,176,548 (-)	NCBI
mRatBN7.2	8	46,261,288 - 46,279,829 (-)	NCBI
Rnor_6.0	8	50,259,244 - 50,277,797 (-)	NCBI
Rnor_5.0	8	48,883,712 - 48,934,692 (-)	NCBI
RGSC_v3.4	8	48,938,556 - 48,957,109 (-)	RGD
Celera	8	45,843,851 - 45,862,380 (-)	RGD

Sequence:

show sequence

TGCTGGGGCCCGAGGAGGGGACGCGCGCCGGAACGCGGCCGTCGGGATCAAGCGAGCGACTGAA
GCGTAACCAGCCGACGCCGCACCCGCTGAGGGCCCGTACGGACCCTCTGCCTCTGTGTAGAATG
AGCCAAGGAGACTCAAACCCAGCAGCTATTCCACATGCAGCAGAAGATATTCAAGGAGATGACA
GGTGGATGTCTCAGCACAATAGGTTTGTTCTGGACTGCAAAGACAAAGAGCCGGACGTGCTGTT
TGTGGGAGACTCCATGGTACAGTTGATGCAGCAGTACGAGATATGGCGGGAGCTGTTTTCCCCA
CTTCATGCTCTTAATTTTGGAATTGGGGGAGACACAACACGACATGTTTTATGGAGACTAAAGA
ACGGAGAGCTGGAGAACATTAAGCCTAAGGTCATTGTTGTCTGGGTAGGAACAAACAACCATGA
AAATACAGCAGAAGAAGTAGCAGGTGGAATTGAGGCTATCGTACAGCTTATAAACACGAGGCAG
CCACAGGCCAAGATCATTGTACTGGGTCTGTTACCTCGAGGTGAGAAGCCCAACCCTTTAAGAC
AAAAGAATGCCAAGGTGAACCAGCTTCTCAAGGTTTCCCTGCCGAAGCTTGCCAATGTGCAGCT
CCTGGATATAGATGGGGGCTTCGTGCACTCGGACGGTGCCATCTCCTGCCACGACATGTTTGAT
TTTCTTCATCTCACAGGAGGGGGCTATGCAAAGATCTGCAAACCCCTCCATGAACTGATCATGC
AGTTGCTGGAGGAAACACCAGAGGAGAAGCAGACCACCATTGCTTGACTGGCCCATCAGTGTTA
ACAGCATCCCAGCTTCCTCAGATCAGTTAGACCACTGGCACTACAGAATCCTTTCTTAAGGCAC
TTTGCATTGTACAATGTTCCTGGATGCTTGTATGTTTGAAGGGGAGGAGGGATTTAAATTGGTC
CTGTATATAAAGGTTTGTTTGAAGAGAGGAGAAAAATTAGCCAAGGAAGATTCATTTGAAACCA
GAAGGGGACTTTTTAGTTGTTTATGTCACACTTGTAGAATTATCACTGTTTTTCCTAGGACAAC
ATCAAGCAAGAGTACAATATGAAGATTCTTTTCTTGGCCCTTTTTTCTATGGATTATGTCATGT
GTGATAATTATCACAGCTACTTGGCTTTAAACTTATTTTTGGTCCAGTTTTAAGGTTCATGAGT
TAGTATGTTGTGTTGTGTTGTTTGATTCATGTATGCTCGGTATTTTTATTAACATATAGCATCA
GATTAAACATGCTTGTCACTCCAGTATGCGAGATGCTATAGTTACAAGTGAGTTTGTTCCTCTC
AGTCTTAAGCAGTGGGAACAAGGTCTGGGGACTGGGATAGAGTTCTTACTGCTGCTGAATATCA
TGTCTGTAATAGACCCGTGCATGCAGCCTTTCCGCTTCCCCTTCATCTCTTCACAGGTGGGTTA
TTTACACCGCAAACTTTTAACTCATTTTTGATCTAGGACTTGCACTGCCGTCAGGACGATCTTA
CTAATGTATAACTCACTCTGTGGTGTTCTGTGATGTAGGGTCTGTGTAATGTTAATCATCCAGA
GTTCTGCTTGTCATCATACCCCCAACCTGTTGTTTTCCTTTGTTTTGTAGGAGGTGGGGGTGGT
GTCAAAATTGTTTCCCATTCCATAATGCCTGATGTTATTTCAAGTTTTATATTATTTTAAGGTG
TATATGTTTGTTTTCGTTTTATATATATTATATATAAATAGATATATTTTACAGTACTGGAATC
AAACCCGGGGCTTAGCACATACTAAGCAAGTGCTCTGCCGCTGAGGTAATCCCTAGACATGCTT
GTTTATTTGCTTGTTTGTTTGGTTGGTTTTTTTATTGGTTTAATTCTTAAATTCTATCAGTAAA
AAAATGTTTTTCCACGGGAAACAGTGAAACTGCTCTCACAATAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006242958 ⟹ XP_006243020

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	55,156,778 - 55,208,800 (-)	NCBI
mRatBN7.2	8	46,260,069 - 46,312,073 (-)	NCBI
Rnor_6.0	8	50,256,969 - 50,310,043 (-)	NCBI
Rnor_5.0	8	48,883,712 - 48,934,692 (-)	NCBI

Sequence:

show sequence

CCCGCGTGGGTCCCTGTTCCTGAGGCGCCGGCTCCCTAGTGCCCCCCTCTGGGGAACAGGCAGT
GAAAACGTCGAGGGTCAGCAGCAACTTCTAAGCTTCCGCCGTGCCTAGCGAGGTGTAGAATGAG
CCAAGGAGACTCAAACCCAGCAGCTATTCCACATGCAGCAGAAGATATTCAAGGAGATGACAGG
TGGATGTCTCAGCACAATAGGTTTGTTCTGGACTGCAAAGACAAAGAGCCGGACGTGCTGTTTG
TGGGAGACTCCATGGTACAGTTGATGCAGCAGTACGAGATATGGCGGGAGCTGTTTTCCCCACT
TCATGCTCTTAATTTTGGAATTGGGGGAGACACAACACGACATGTTTTATGGAGACTAAAGAAC
GGAGAGCTGGAGAACATTAAGCCTAAGGTCATTGTTGTCTGGGTAGGAACAAACAACCATGAAA
ATACAGCAGAAGAAGTAGCAGGTGGAATTGAGGCTATCGTACAGCTTATAAACACGAGGCAGCC
ACAGGCCAAGATCATTGTACTGGGTCTGTTACCTCGAGGTGAGAAGCCCAACCCTTTAAGACAA
AAGAATGCCAAGGTGAACCAGCTTCTCAAGGTTTCCCTGCCGAAGCTTGCCAATGTGCAGCTCC
TGGATATAGATGGGGGCTTCGTGCACTCGGACGGTGCCATCTCCTGCCACGACATGTTTGATTT
TCTTCATCTCACAGGAGGGGGCTATGCAAAGATCTGCAAACCCCTCCATGAACTGATCATGCAG
TTGCTGGAGGAAACACCAGAGGAGAAGCAGACCACCATTGCTTGACTGGCCCATCAGTGTTAAC
AGCATCCCAGCTTCCTCAGATCAGTTAGACCACTGGCACTACAGAATCCTTTCTTAAGGCACTT
TGCATTGTACAATGTTCCTGGATGCTTGTATGTTTGAAGGGGAGGAGGGATTTAAATTGGTCCT
GTATATAAAGGTTTGTTTGAAGAGAGGAGAAAAATTAGCCAAGGAAGATTCATTTGAAACCAGA
AGGGGACTTTTTAGTTGTTTATGTCACACTTGTAGAATTATCACTGTTTTTCCTAGGACAACAT
CAAGCAAGAGTACAATATGAAGATTCTTTTCTTGGCCCTTTTTTCTATGGATTATGTCATGTGT
GATAATTATCACAGCTACTTGGCTTTAAACTTATTTTTGGTCCAGTTTTAAGGTTCATGAGTTA
GTATGTTGTGTTGTGTTGTTTGATTCATGTATGCTCGGTATTTTTATTAACATATAGCATCAGA
TTAAACATGCTTGTCACTCCAGTATGCGAGATGCTATAGTTACAAGTGAGTTTGTTCCTCTCAG
TCTTAAGCAGTGGGAACAAGGTCTGGGGACTGGGATAGAGTTCTTACTGCTGCTGAATATCATG
TCTGTAATAGACCCGTGCATGCAGCCTTTCCGCTTCCCCTTCATCTCTTCACAGGTGGGTTATT
TACACCGCAAACTTTTAACTCATTTTTGATCTAGGACTTGCACTGCCGTCAGGACGATCTTACT
AATGTATAACTCACTCTGTGGTGTTCTGTGATGTAGGGTCTGTGTAATGTTAATCATCCAGAGT
TCTGCTTGTCATCATACCCCCAACCTGTTGTTTTCCTTTGTTTTGTAGGAGGTGGGGGTGGTGT
CAAAATTGTTTCCCATTCCATAATGCCTGATGTTATTTCAAGTTTTATATTATTTTAAGGTGTA
TATGTTTGTTTTCGTTTTATATATATTATATATAAATAGATATATTTTACAGTACTGGAATCAA
ACCCGGGGCTTAGCACATACTAAGCAAGTGCTCTGCCGCTGAGGTAATCCCTAGACATGCTTGT
TTATTTGCTTGTTTGTTTGGTTGGTTTTTTTATTGGTTTAATTCTTAAATTCTATCAGTAAAAA
AATGTTTTTCCACGGGAAACAGTGAAACTGCTCTCACAATAGATGTGCTCTCTATGTCTTTTTT
TTCCCCCCCTTTTGTTTTTCTTTTTTGAGGCAGGGTTTCTCTGTATAGTCCTGGCTATCCTGAA
GCTCTGTAGGCCAGGCTGGCCTTGAACTCAGAGATCAATTGCCTCTGCTTCCCAAGCGCTGAAA
TTAAAGGCGTGTTCCCACCACACCTGGCTTTAGATGTGCTATCTTTAGTCTACTATTTTAGTAA
AGATTAAACTAGGTTCCTTTTGTTGGTCTATGAGTCTCACAGTATAGCTCTGCCTGGCCTGGAG
TTTGCTTGTAGACCAGGTTAGTGTTGAACTCACAGAGACCTGCCTGCCTCTGCCTCCTGAGGAC
TGAGAGTAAAGGCGGGCACCACCATGGAGATGGCTCACTGATCATTTAAGGTTCCTTATATAAT
TTAGTGTCTTGGTCGAGATTTCAAGAGAGCTCCTTACATTCCGTCTGGTTTGCTTGAGCTATGC
AAACTGCCACTTGAGAAAATAATACATTATTGGTTGTCCATAAACGATCTACAAACATTTTAAA
CTGGACCAGGTTGGGGACTGAGGTAACTCATTGAATGTGCTCTACAATGCTTTTGCTCAATGGT
CACATTCAGTAGCTCTGTGATCTAGGCTTTCTGTTCCTCTTCCAGAGCAGCCGACAGGGCTGTT
AGAGGAACTCTTGGTTTGTGCTGAGACCCACCTGACGGAGAAAGATAGAAGTTGAAGTGTTTTT
TCCCTGGTGAGCATCTGTGTAGAATTTAACACATATCGTCATGAATGTATCATGTCTTCATTAG
CAACAGGAAAATACACATGGTCTTTACTAATATTGTCTACCACAGTGAAATTCCCTTTTATTTT
TTTAGTAGCCTAAGTTCTTGAGTTTTTCAAGACATTGTTTTCTGAACTGAGTATAATTTTAGGA
AGGGAGAGTTAATTAAGCCAGAATTTTGGGTGTAAAAAGAACATTTTGACCCAGGTGTTCCTGT
GATCCTCAGAGAGTAGGAATATGGTCCAAATGAGTCCATTAGGTCACTCCTGCAGCATGCGCTT
GTAGTTTCTCTTGACCAAGGATGAACTAGTCCTGTGATCTGGCCTTCAGCTCCTGCACATGTGG
TTAAACCTCAGATGTTACTACGTTTTATACCTGCCAGAGCTCCTCAAGCAATAGCATTTGAGCC
ACTAGCCTTTTAAATAAAACTCTGTCCTATTGCTGACATGCAGATTCCGAGTCCACTGTCATTT
CTTGCCAGGTTCATTTGTGCTGTTTTCGGGGGACAATGGTTGATCATTCTTTCTTTGGTTGACA
TCCCTGATTGCTTCAGTGACAGAACTGGTTAGTCTATGTGGTTTTTTAAGATGTGACGAGATCT
ACTTTGCTTTGGTTATGGGGCCAGGCAGTCAGCACAGGTGCTGCTTTGTTCCCTTTTTTTTTTT
TTTTTTTTTTTTTTTTGTAGGTGGGTGGTTTTCTTAGCAGAGTCTATATGTGTGTACCCTGACT
GCCTTTGAACTCCTGGTGATCCTCCTGTTTTGTCTCCCCAGTAGTGGAGATACCGGCCCATTCC
ACTATGCTTGACTTGTTAGGCTCCTTTCCCGACATTTTTCTTTTGAGACAGGGTCTCAGTGTAG
TACAGTCTGGCTTAGCATGTGGCCGAGGGTGACCTTGAACTCAGTCCTGCTGCTGCTACCTTCC
GAGTTCAGTACTAGAGCCATGTCTCTACTGTGGCGGGTTGGAGACGCCCTGCCAAATGGATGGT
GTGTTGCAGGTGGCTTGGGTGCCCTGGCACTTTAGATTACCATTGGCAGCGCACTGCCACCATG
TCAGGTCTGCTAGGACTGTTGAGGACTTCTGTCCAATCCTGATGTTTCTGTCCAAACCTTCTCC
CAGTAAGTAAGTCTTGGCAGCTCATGCCTTGTTCTTCAGAATTCTAACTCACTGTTAAAAAAAG
TCCCAATTTCTGTTTGCATTTTCAACCCGACCACTTAACTCTGCCTGAAACCTGTCTGTGCTAA
GGTGTGTGAATATTGCCAGTTTTATATTTATTACAGTGATGAAGAAACGAGAAGTAGGAAAGGG
AGCATGGCCAGCTCCTGACTCTGAGCAGTTTGTATGGGAACAGTGAGTGGGGGCTTGCCTGTGG
TCTTCCCCTCCAGGACCACTGTAGCAGGCTGACTGCACCTCCCCAGGGGAGCTTGTTACCATGC
TTTGGCAAAGGCTTCTTGACTAGAATCCATTCTGTTCAGTGCTCATTTAATATAAAAGTCAACA
TTTCACTGCAAA

hide sequence

RefSeq Acc Id:

XM_039082081 ⟹ XP_038938009

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	55,156,778 - 55,175,722 (-)	NCBI
mRatBN7.2	8	46,260,069 - 46,279,862 (-)	NCBI

RefSeq Acc Id:

XM_039082082 ⟹ XP_038938010

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	55,156,778 - 55,176,302 (-)	NCBI
mRatBN7.2	8	46,260,069 - 46,279,529 (-)	NCBI

RefSeq Acc Id:

XM_063266074 ⟹ XP_063122144

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	55,156,778 - 55,172,984 (-)	NCBI

RefSeq Acc Id:

XM_063266075 ⟹ XP_063122145

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	55,156,778 - 55,176,267 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_071782	(Get FASTA)	NCBI Sequence Viewer
	XP_006243020	(Get FASTA)	NCBI Sequence Viewer
	XP_038938009	(Get FASTA)	NCBI Sequence Viewer
	XP_038938010	(Get FASTA)	NCBI Sequence Viewer
	XP_063122144	(Get FASTA)	NCBI Sequence Viewer
	XP_063122145	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAC27974	(Get FASTA)	NCBI Sequence Viewer
	AAH81714	(Get FASTA)	NCBI Sequence Viewer
	EDL95390	(Get FASTA)	NCBI Sequence Viewer
	EDL95391	(Get FASTA)	NCBI Sequence Viewer
	EDL95392	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000068672
	ENSRNOP00000091075.1
GenBank Protein	O35264	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_071782 ⟸ NM_022387

- UniProtKB:

O35264 (UniProtKB/Swiss-Prot), A6J468 (UniProtKB/TrEMBL), A0A8L2R003 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSQGDSNPAAIPHAAEDIQGDDRWMSQHNRFVLDCKDKEPDVLFVGDSMVQLMQQYEIWRELFS
PLHALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNHENTAEEVAGGIEAIVQLINTR
QPQAKIIVLGLLPRGEKPNPLRQKNAKVNQLLKVSLPKLANVQLLDIDGGFVHSDGAISCHDMF
DFLHLTGGGYAKICKPLHELIMQLLEETPEEKQTTIA

hide sequence

RefSeq Acc Id:	XP_006243020 ⟸ XM_006242958
- Peptide Label:	isoform X1
- UniProtKB:	O35264 (UniProtKB/Swiss-Prot), A6J468 (UniProtKB/TrEMBL), A0A8L2R003 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSQGDSNPAAIPHAAEDIQGDDRWMSQHNRFVLDCKDKEPDVLFVGDSMVQLMQQYEIWRELFS PLHALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNHENTAEEVAGGIEAIVQLINTR QPQAKIIVLGLLPRGEKPNPLRQKNAKVNQLLKVSLPKLANVQLLDIDGGFVHSDGAISCHDMF DFLHLTGGGYAKICKPLHELIMQLLEETPEEKQTTIA hide sequence

Ensembl Acc Id:

ENSRNOP00000068672 ⟸ ENSRNOT00000082508

RefSeq Acc Id:	XP_038938009 ⟸ XM_039082081
- Peptide Label:	isoform X1
- UniProtKB:	O35264 (UniProtKB/Swiss-Prot), A6J468 (UniProtKB/TrEMBL), A0A8L2R003 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038938010 ⟸ XM_039082082
- Peptide Label:	isoform X1
- UniProtKB:	O35264 (UniProtKB/Swiss-Prot), A6J468 (UniProtKB/TrEMBL), A0A8L2R003 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000091075 ⟸ ENSRNOT00000111151

RefSeq Acc Id:	XP_063122145 ⟸ XM_063266075
- Peptide Label:	isoform X1
- UniProtKB:	O35264 (UniProtKB/Swiss-Prot), A6J468 (UniProtKB/TrEMBL), A0A8L2R003 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063122144 ⟸ XM_063266074
- Peptide Label:	isoform X1
- UniProtKB:	O35264 (UniProtKB/Swiss-Prot), A6J468 (UniProtKB/TrEMBL), A0A8L2R003 (UniProtKB/TrEMBL)

Protein Domains

SGNH hydrolase-type esterase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-O35264-F1-model_v2	AlphaFold	O35264	1-229	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13695924

Promoter ID:

EPDNEW_R6449

Type:

multiple initiation site

Name:

Pafah1b2_1

Description:

platelet-activating factor acetylhydrolase 1b, catalytic subunit2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	8	50,277,802 - 50,277,862	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620332	AgrOrtholog
BioCyc Gene	G2FUF-30658	BioCyc
Ensembl Genes	ENSRNOG00000057102	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000082508	ENTREZGENE
	ENSRNOT00000111151.1	UniProtKB/Swiss-Prot
Gene3D-CATH	3.40.50.1110	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7108923	IMAGE-MGC_LOAD
InterPro	SGNH_hydro	UniProtKB/Swiss-Prot
	SGNH_hydro_sf	UniProtKB/Swiss-Prot
KEGG Report	rno:64189	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:93124	IMAGE-MGC_LOAD
NCBI Gene	64189	ENTREZGENE
PANTHER	PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE	UniProtKB/Swiss-Prot
	PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB SUBUNIT ALPHA2	UniProtKB/Swiss-Prot
Pfam	Lipase_GDSL_2	UniProtKB/Swiss-Prot
PhenoGen	Pafah1b2	PhenoGen
RatGTEx	ENSRNOG00000057102	RatGTEx
Superfamily-SCOP	SGNH hydrolase	UniProtKB/Swiss-Prot
UniProt	A0A8L2R003	ENTREZGENE, UniProtKB/TrEMBL
	A6J468	ENTREZGENE, UniProtKB/TrEMBL
	O35264	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2012-05-03	Pafah1b2	platelet-activating factor acetylhydrolase 1b, catalytic subunit 2	Pafah1b2	platelet-activating factor acetylhydrolase, isoform 1b, subunit 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2009-04-21	Pafah1b2	platelet-activating factor acetylhydrolase, isoform 1b, subunit 2	Pafah1b2	platelet-activating factor acetylhydrolase, isoform Ib, beta subunit	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-11-06	Pafah1b2	platelet-activating factor acetylhydrolase, isoform Ib, beta subunit	Pafah1b2	platelet-activating factor acetylhydrolase, isoform 1b, alpha2 subunit	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-20	Pafah1b2	platelet-activating factor acetylhydrolase, isoform 1b, alpha2 subunit		platelet-activating factor acetylhydrolase alpha 2 subunit (PAF-AH alpha 2)	Name updated	1299863	APPROVED
2002-08-07	Pafah1b2	platelet-activating factor acetylhydrolase alpha 2 subunit (PAF-AH alpha 2)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Annotations - KEGG (archival)

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RGD Manual Annotations

Imported Annotations - KEGG (archival)