Msmo1 (methylsterol monooxygenase 1) - Rat Genome Database

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Gene: Msmo1 (methylsterol monooxygenase 1) Rattus norvegicus
Analyze
Symbol: Msmo1
Name: methylsterol monooxygenase 1
RGD ID: 620281
Description: Predicted to enable C-4 methylsterol oxidase activity. Predicted to be involved in sterol biosynthetic process. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human MSMO1 (methylsterol monooxygenase 1); PARTICIPATES IN alendronate pharmacodynamics pathway; cholesterol biosynthetic pathway; cholesterol ester storage disease pathway; INTERACTS WITH 1-(3-(trifluoromethyl)phenyl)piperazine; 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine; 1-benzylpiperazine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: C-4 methylsterol oxidase; methylsterol monooxygenase; neuropep 1; neurorep 1; RANP-1; Sc4mol; sterol-C4-methyl oxidase; sterol-C4-methyl oxidase-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81629,747,113 - 29,764,360 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1629,747,137 - 29,764,445 (+)EnsemblGRCr8
mRatBN7.21624,980,680 - 24,997,927 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1624,980,697 - 24,998,016 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1628,345,719 - 28,362,941 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01631,780,075 - 31,797,297 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01627,735,138 - 27,752,360 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01626,859,441 - 26,875,880 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1626,859,397 - 26,875,973 (+)Ensemblrn6Rnor6.0
Rnor_5.01626,738,367 - 26,754,806 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41626,698,324 - 26,716,247 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1625,065,073 - 25,082,320 (+)NCBICelera
RGSC_v3.11626,698,321 - 26,716,245 (+)NCBI
Cytogenetic Map16p13NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(S)-nicotine  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-(3-(trifluoromethyl)phenyl)piperazine  (EXP)
1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine  (EXP)
1-benzylpiperazine  (EXP)
1-naphthyl isothiocyanate  (EXP)
14-demethyllanosterol  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,6-dimethyl-4-tridecylmorpholine  (ISO)
2-hydroxypropanoic acid  (ISO)
2-methoxyethanol  (EXP)
2-methylcholine  (ISO)
22-Hydroxycholesterol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-bromo-2'-deoxyuridine  (ISO)
5alpha-cholest-7-en-3beta-ol  (ISO)
6-propyl-2-thiouracil  (EXP)
8-Br-cAMP  (ISO)
acetamide  (EXP)
Acetyl tributyl citrate  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
aluminium atom  (ISO)
aluminium(0)  (ISO)
amiodarone  (EXP)
amitriptyline  (EXP)
Archazolid B  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
azathioprine  (ISO)
benzalkonium chloride  (ISO)
benzo[a]pyrene  (ISO)
beta-naphthoflavone  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
bromobenzene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (EXP)
calcitriol  (ISO)
capsaicin  (ISO)
carbon nanotube  (ISO)
celastrol  (ISO)
cetrorelix  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (ISO)
clobetasol  (ISO)
clomipramine  (EXP)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
corn oil  (EXP)
corosolic acid  (ISO)
coumarin  (EXP)
Cuprizon  (EXP)
curcumin  (EXP,ISO)
cyclosporin A  (ISO)
cylindrospermopsin  (ISO)
cyproconazole  (EXP,ISO)
DDE  (EXP,ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP,ISO)
dicrotophos  (ISO)
difenoconazole  (EXP)
dioxygen  (ISO)
diuron  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
epoxiconazole  (EXP,ISO)
erlotinib hydrochloride  (ISO)
ethanol  (EXP,ISO)
ethyl methanesulfonate  (ISO)
fenarimol  (EXP)
fenfluramine  (ISO)
fenofibrate  (EXP)
fenpropidin  (ISO)
flavonoids  (EXP)
fluoranthene  (ISO)
fluoxetine  (ISO)
flusilazole  (EXP,ISO)
folic acid  (ISO)
formaldehyde  (ISO)
fumonisin B1  (ISO)
furan  (EXP)
Ganoderic acid A  (ISO)
gedunin  (ISO)
genistein  (ISO)
Heptachlor epoxide  (ISO)
hexaconazole  (ISO)
hydrogen peroxide  (ISO)
imipramine  (EXP)
indometacin  (ISO)
iron dichloride  (ISO)
isoflurane  (ISO)
isotretinoin  (ISO)
kainic acid  (ISO)
ketamine  (EXP)
ketoconazole  (EXP,ISO)
L-methionine  (ISO)
lead diacetate  (ISO)
lead(0)  (ISO)
leflunomide  (ISO)
lucanthone  (ISO)
LY294002  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
metformin  (EXP)
methapyrilene  (EXP)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
methylparaben  (ISO)
mevastatin  (ISO)
miconazole  (ISO)
N(4)-hydroxycytidine  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
N-nitrosodiethylamine  (EXP)
naled  (ISO)
nickel dichloride  (ISO)
nicotine  (ISO)
nitrofen  (EXP)
O-methyleugenol  (ISO)
obeticholic acid  (ISO)
ochratoxin A  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
paclitaxel  (ISO)
pamidronate  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
phenobarbital  (EXP,ISO)
phenylephrine  (EXP)
phenylpropanolamine  (ISO)
picoxystrobin  (ISO)
pirinixic acid  (ISO)
piroxicam  (ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
prochloraz  (EXP)
progesterone  (ISO)
propiconazole  (EXP,ISO)
quercetin  (ISO)
quinolin-8-ol  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
ritodrine  (ISO)
rotenone  (EXP,ISO)
senecionine  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
spiroxamine  (ISO)
sulindac sulfide  (ISO)
sunitinib  (ISO)
T-2 toxin  (ISO)
tamoxifen  (ISO)
tebuconazole  (EXP,ISO)
temozolomide  (ISO)
testosterone  (ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (ISO)
triadimefon  (ISO)
trichloroethene  (ISO)
triphenyl phosphate  (EXP,ISO)
Triptolide  (ISO)
triptonide  (ISO)
tunicamycin  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)
xylitol  (ISO)
Yessotoxin  (ISO)
zoledronic acid  (ISO)
zymosterol  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
10. Identification and characterization of a novel gene (neurorep 1) expressed in nerve cells and up-regulated after axotomy. Uwabe K, etal., Neuroscience 1997 Sep;80(2):501-9.
Additional References at PubMed
PMID:15489334   PMID:28970091  


Genomics

Comparative Map Data
Msmo1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81629,747,113 - 29,764,360 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1629,747,137 - 29,764,445 (+)EnsemblGRCr8
mRatBN7.21624,980,680 - 24,997,927 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1624,980,697 - 24,998,016 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1628,345,719 - 28,362,941 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01631,780,075 - 31,797,297 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01627,735,138 - 27,752,360 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01626,859,441 - 26,875,880 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1626,859,397 - 26,875,973 (+)Ensemblrn6Rnor6.0
Rnor_5.01626,738,367 - 26,754,806 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41626,698,324 - 26,716,247 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1625,065,073 - 25,082,320 (+)NCBICelera
RGSC_v3.11626,698,321 - 26,716,245 (+)NCBI
Cytogenetic Map16p13NCBI
MSMO1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384165,327,669 - 165,343,164 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4165,327,667 - 165,343,180 (+)Ensemblhg38GRCh38
GRCh374166,248,821 - 166,264,316 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364166,468,268 - 166,483,675 (+)NCBIBuild 36Build 36hg18NCBI36
Build 344166,606,462 - 166,621,472NCBI
Celera4163,584,245 - 163,599,652 (+)NCBICelera
Cytogenetic Map4q32.3NCBI
HuRef4162,000,630 - 162,016,125 (+)NCBIHuRef
CHM1_14166,225,277 - 166,240,769 (+)NCBICHM1_1
T2T-CHM13v2.04168,673,661 - 168,689,162 (+)NCBIT2T-CHM13v2.0
Msmo1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39865,171,157 - 65,186,822 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl865,171,173 - 65,186,826 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38864,718,123 - 64,733,578 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl864,718,139 - 64,733,792 (-)Ensemblmm10GRCm38
MGSCv37867,196,942 - 67,212,375 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36867,610,337 - 67,625,770 (-)NCBIMGSCv36mm8
Celera867,282,044 - 67,297,655 (-)NCBICelera
Cytogenetic Map8B3.1NCBI
cM Map832.3NCBI
Msmo1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540339,989,409 - 40,009,890 (-)Ensembl
ChiLan1.0NW_00495540339,991,528 - 40,009,047 (-)NCBIChiLan1.0ChiLan1.0
MSMO1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23163,072,271 - 163,092,185 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14163,430,124 - 163,450,181 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04157,523,099 - 157,538,508 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14169,606,760 - 169,622,218 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4169,606,809 - 169,622,212 (+)EnsemblpanPan2panpan1.1
MSMO1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11561,293,769 - 61,307,285 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX8,144,335 - 8,145,216 (+)EnsemblcanFam3CanFam3.1
CanFam3.1 Ensembl1561,293,769 - 61,307,285 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1561,603,112 - 61,616,553 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01562,155,920 - 62,169,411 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1562,155,920 - 62,169,411 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11561,337,450 - 61,350,976 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01561,380,852 - 61,394,331 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01561,774,960 - 61,788,473 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Msmo1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494317,892,375 - 17,906,243 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936555664,158 - 678,208 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936555664,171 - 678,082 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MSMO1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl843,726,858 - 43,744,713 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1843,726,834 - 43,745,784 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2845,557,631 - 45,618,277 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MSMO1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.17111,688,591 - 111,704,765 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl7111,688,604 - 111,704,849 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603791,538,871 - 91,557,835 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Msmo1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475811,629,007 - 11,644,263 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475811,629,824 - 11,644,071 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Msmo1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11324,392,064 - 24,401,655 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Msmo1
120 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:430
Count of miRNA genes:235
Interacting mature miRNAs:280
Transcripts:ENSRNOT00000044171
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411664Foco30Food consumption QTL 30110.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)16435482249354822Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)1638712345387123Rat
1549842Bp248Blood pressure QTL 2480.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1638712345387123Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)16423421249757901Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16133425095Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16423421266955197Rat
2302057Pia29Pristane induced arthritis QTL 293.60.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)162846870173468701Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16139568015Rat
2303566Bw90Body weight QTL 902body mass (VT:0001259)body weight (CMO:0000012)16139568015Rat
737819Hcas4Hepatocarcinoma susceptibility QTL 44.43liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)16423421253708481Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1683908666195506Rat
2306902Bp339Blood pressure QTL 3390.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16338679049757901Rat
1354625Despr7Despair related QTL 73.160.016locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16474422249744222Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)1683908666195506Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1683908666195506Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161773081872536785Rat
2293343Glom16Glomerulus QTL 167.4kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1683908652786090Rat
2301406Kidm39Kidney mass QTL 390.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)161590580260905802Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1683908666195506Rat
6903319Bw114Body weight QTL 1142.70.0037body mass (VT:0001259)body weight (CMO:0000012)16330168348301683Rat

Markers in Region
RH126400  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21624,997,739 - 24,997,977 (+)MAPPERmRatBN7.2
Rnor_6.01626,875,693 - 26,875,930NCBIRnor6.0
Rnor_5.01626,754,619 - 26,754,856UniSTSRnor5.0
RGSC_v3.41626,716,060 - 26,716,297UniSTSRGSC3.4
Celera1625,082,133 - 25,082,370UniSTS
Cytogenetic Map16p13UniSTS
RH128075  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21624,997,552 - 24,997,755 (+)MAPPERmRatBN7.2
Rnor_6.01626,875,506 - 26,875,708NCBIRnor6.0
Rnor_5.01626,754,432 - 26,754,634UniSTSRnor5.0
RGSC_v3.41626,715,873 - 26,716,075UniSTSRGSC3.4
Celera1625,081,946 - 25,082,148UniSTS
RH 3.4 Map16314.4UniSTS
Cytogenetic Map16p13UniSTS
RH136901  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21624,997,658 - 24,997,857 (+)MAPPERmRatBN7.2
Rnor_6.01626,875,612 - 26,875,810NCBIRnor6.0
Rnor_5.01626,754,538 - 26,754,736UniSTSRnor5.0
RGSC_v3.41626,715,979 - 26,716,177UniSTSRGSC3.4
Celera1625,082,052 - 25,082,250UniSTS
RH 3.4 Map16311.6UniSTS
Cytogenetic Map16p13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000044171   ⟹   ENSRNOP00000043782
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1629,747,137 - 29,764,445 (+)Ensembl
mRatBN7.2 Ensembl1624,980,697 - 24,998,016 (+)Ensembl
Rnor_6.0 Ensembl1626,859,397 - 26,875,973 (+)Ensembl
RefSeq Acc Id: NM_080886   ⟹   NP_543162
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81629,747,113 - 29,764,360 (+)NCBI
mRatBN7.21624,980,680 - 24,997,927 (+)NCBI
Rnor_6.01626,859,441 - 26,875,880 (+)NCBI
Rnor_5.01626,738,367 - 26,754,806 (+)NCBI
RGSC_v3.41626,698,324 - 26,716,247 (+)RGD
Celera1625,065,073 - 25,082,320 (+)RGD
Sequence:
RefSeq Acc Id: NP_543162   ⟸   NM_080886
- UniProtKB: O35532 (UniProtKB/Swiss-Prot),   A6KFP1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000043782   ⟸   ENSRNOT00000044171
Protein Domains
Fatty acid hydroxylase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O35532-F1-model_v2 AlphaFold O35532 1-293 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700067
Promoter ID:EPDNEW_R10589
Type:initiation region
Name:Msmo1_1
Description:methylsterol monooxygenase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01626,859,461 - 26,859,521EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620281 AgrOrtholog
BioCyc Gene G2FUF-11629 BioCyc
Ensembl Genes ENSRNOG00000032297 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000044171 ENTREZGENE
  ENSRNOT00000044171.3 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:6918081 IMAGE-MGC_LOAD
InterPro Fatty_acid_hydroxylase UniProtKB/Swiss-Prot
  Sterol_Desaturase_Related UniProtKB/Swiss-Prot
KEGG Report rno:140910 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72715 IMAGE-MGC_LOAD
NCBI Gene 140910 ENTREZGENE
PANTHER STEROL DESATURASE UniProtKB/Swiss-Prot
Pfam FA_hydroxylase UniProtKB/Swiss-Prot
PhenoGen Msmo1 PhenoGen
RatGTEx ENSRNOG00000032297 RatGTEx
UniProt A6KFP1 ENTREZGENE, UniProtKB/TrEMBL
  MSMO1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-09-29 Msmo1  methylsterol monooxygenase 1  Sc4mol  sterol-C4-methyl oxidase-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-02-26 Sc4mol  sterol-C4-methyl oxidase-like      Symbol and Name status set to approved 625702 APPROVED
2002-08-07 Sc4mol  sterol-C4-methyl oxidase-like      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_domains contains an ecto-5'-nucleotidase consensus sequence 633977