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Gene: Sert1 (Sertoli cell protein 1) Rattus norvegicus

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Symbol:

Sert1

Name:

Sertoli cell protein 1

RGD ID:

620279

Description:

INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 6-propyl-2-thiouracil; amitrole

Type:

ncrna

RefSeq Status:

VALIDATED

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	156,568,048 - 156,572,028 (-)	NCBI	GRCr8	GRCr8		GRCr8
mRatBN7.2	3	136,114,902 - 136,118,882 (-)	NCBI	mRatBN7.2	mRatBN7.2
UTH_Rnor_SHR_Utx	3	140,066,999 - 140,070,999 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	148,651,147 - 148,655,147 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	146,340,513 - 146,344,493 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	142,999,585 - 143,003,565 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	3	149,410,143 - 149,414,233 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Celera	3	134,957,960 - 134,961,940 (-)	NCBI		Celera
RGSC_v3.1	3	137,316,458 - 137,320,437 (-)	NCBI
Cytogenetic Map	3	q41	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

2,2',4,4'-Tetrabromodiphenyl ether (EXP)

6-propyl-2-thiouracil (EXP)

amitrole (EXP)

ammonium chloride (EXP)

cisplatin (EXP)

flavonoids (EXP)

methimazole (EXP)

References

References - curated

#	Reference Title	Reference Citation
1.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
3.	Information Derived from GenBank Report	RGD, Sept. 2003

Additional References at PubMed

PMID:8889548	PMID:14693373

Genomics

Variants

Variants in Sert1
28 total Variants

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
12879876	Bw182	Body weight QTL 182		0.003	body mass (VT:0001259)	body weight (CMO:0000012)	3	141555229	186555229	Rat
2301411	Bp320	Blood pressure QTL 320		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	141555229	186555229	Rat
1582233	Insul10	Insulin level QTL 10	5.4	0.0015	blood insulin amount (VT:0001560)	serum insulin level times blood glucose level (CMO:0002040)	3	133259579	178259579	Rat
12879872	Cm97	Cardiac mass QTL 97		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	141555229	186555229	Rat
12879873	Cm96	Cardiac mass QTL 96		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	3	141555229	186555229	Rat
1578653	Vnigr3	Vascular neointimal growth QTL 3	3.1		artery morphology trait (VT:0002191)	artery neointimal hyperplastic lesion area (CMO:0001414)	3	151075912	189428310	Rat
2302373	Gluco39	Glucose level QTL 39	5.01		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	3	129154923	182114333	Rat
12879874	Cm98	Cardiac mass QTL 98		0.005	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	3	141555229	186555229	Rat
12879875	Kidm64	Kidney mass QTL 64		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	141555229	186555229	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	51581665	184004958	Rat
2292591	Esta4	Estrogen-induced thymic atrophy QTL 4			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	3	67641776	167835660	Rat
1578754	Stresp16	Stress response QTL 16	4	0.001	blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	3	133134628	178134628	Rat
1582213	Insul6	Insulin level QTL 6	3.7	0.0009	blood insulin amount (VT:0001560)	calculated serum insulin level (CMO:0000359)	3	155759447	189428310	Rat
1300173	Rf11	Renal function QTL 11	3.38		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	3	141508991	166376254	Rat
9589106	Insul23	Insulin level QTL 23	13.86	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	3	152055202	189428310	Rat
8694437	Bw167	Body weight QTL 167	22.46	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	3	112250810	157250810	Rat
10755461	Coatc16	Coat color QTL 16			coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	3	142898802	187898802	Rat
8662816	Vetf4	Vascular elastic tissue fragility QTL 4	4		renal artery integrity trait (VT:0010642)	number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)	3	79649560	177741895	Rat
1559282	Emca5	Estrogen-induced mammary cancer QTL 5	3.9		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	3	145335553	189428310	Rat
1354611	Despr2	Despair related QTL 2	3.03	0.0028	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	3	117537367	162537367	Rat
2303620	Vencon4	Ventilatory control QTL 4	3.9		respiration trait (VT:0001943)	tidal volume (CMO:0000222)	3	125116475	170116475	Rat
1582256	Insul9	Insulin level QTL 9	4.4	0.0016	blood insulin amount (VT:0001560)	absolute change in serum insulin level (CMO:0002038)	3	155759447	189428310	Rat
1576306	Schws3	Schwannoma susceptibility QTL 3		0.001	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	3	139299381	184299381	Rat
5686842	Rf59	Renal function QTL 59			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	3	122395989	167395989	Rat
1300159	Kidm4	Kidney mass QTL 4	3.83		kidney mass (VT:0002707)	right kidney wet weight to body weight ratio (CMO:0001953)	3	141508991	177728348	Rat
2301971	Cm71	Cardiac mass QTL 71	4.63		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	3	131036586	176036586	Rat
631673	Iddm13	Insulin dependent diabetes mellitus QTL 13	1.3	0.663	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	3	137114333	182114333	Rat
1582248	Insul7	Insulin level QTL 7	3.9	0.0041	blood insulin amount (VT:0001560)	calculated serum insulin level (CMO:0000359)	3	155759447	189428310	Rat
2301970	Bw81	Body weight QTL 81	5.19		body mass (VT:0001259)	body weight (CMO:0000012)	3	131036586	176036586	Rat
1581546	Pur13	Proteinuria QTL 13	2.93	0.0335	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	3	98651826	167012663	Rat
1578666	Vnigr1	Vascular neointimal growth QTL 1	4.6		artery morphology trait (VT:0002191)	artery lumen area (CMO:0001409)	3	151075912	189428310	Rat
1578656	Vnigr2	Vascular neointimal growth QTL 2	4.2		artery morphology trait (VT:0002191)	lesioned artery residual lumen area (CMO:0001417)	3	151075912	189428310	Rat
12879871	Am7	Aortic mass QTL 7		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	3	141555229	186555229	Rat
631541	Bp81	Blood pressure QTL 81	4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	144575244	189428310	Rat
724532	Cm17	Cardiac mass QTL 17	2		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	3	116188400	161188400	Rat

Markers in Region

RH143747

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	136,115,199 - 136,115,364 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	142,999,883 - 143,000,047	NCBI	Rnor6.0
Rnor_5.0	3	149,410,443 - 149,410,607	UniSTS	Rnor5.0
RGSC_v3.4	3	137,411,182 - 137,411,346	UniSTS	RGSC3.4
Celera	3	134,958,258 - 134,958,422	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	hemolymphoid system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	sensory system	visual system
7	1	15	52	65	131	90	11	51	34	32	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NR_130708	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AA901007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC110699	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF077195	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

NR_130708

RefSeq Status:

VALIDATED

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	156,568,048 - 156,572,028 (-)	NCBI
mRatBN7.2	3	136,114,902 - 136,118,882 (-)	NCBI
Rnor_6.0	3	142,999,585 - 143,003,565 (-)	NCBI
Celera	3	134,957,960 - 134,961,940 (-)	NCBI

Sequence:

show sequence

CCCGGATTTACCACCCGTGGCTATCCAAGGCCGCGCCTGCGCAGAAGACAGCAATGGTTGGGGA
CAGGTTTATTTAGCGGAGTTTTGGTCTTCAGGTTGCTGGAAGCTGAATTTTCGAGCACTCCCGG
GTGCTGCGTTTGGCCAAGTCTTGGCTTAGGGCACGGCCAAGGTGGGACGGGAAGGCTGGCGCTG
CTTCGTATTGAATCCTTCCGCTCTAAATCCCACTGTTGATCTTAATTAAAGCCTGTTCATTTGA
AAATCCTGCTCTGACACTTCCAGTTCCTGCTCCTGCTGCAAAGAGGCGATGTTAAGCCAATTAC
ATGAAATACAAGTTCACTTCAATTTCAAGATCATCTGGATTTCAGAACTACAGATCTGACCCAT
ACATATCCTTGTGCCAAGGGACTGGTAAGATAACAAGGCAGACGCCAAAGAACCTCTTCAAATC
AACAAGAAATCACCAGCCGATAAAGAATGCTACAGGACAATTCTCATTTGTATATGAGTAGGGT
CCAATTCTGGAACACACAACAAACTGGGCCACACCCTCCATTGCGCGCAGCCAGTTGATTGGTA
TAGCCTCCCAGGCCAGGCAGCGCTTTGTCCCTCACACTAGGAGACTCAGGCAGCAGCTGGGGAC
CAGGTCACTCTGCTTGCCGTTGAGTTTCTCGGGGAACCCTCTTGTAATTGGTTCTTGGTGGTCG
CGAGGTGATGACGTTGACACCCCCATGTCCTAAAATGTGGCGCTGTGGTAGTCTTACAGAAGTG
AGAGGCTCTGCGGTCCTGTGACATCCCCTCCAAGCCGAGCAGCCATCTCTACCACGCGGCCGCG
CTGGAGCCTCCCGGCGGCCCAGAGAGAGAGCAAGTCGTGCGTTGGTGTGGACGGAGGAACCACG
CGGTGTTGTCATGGGCCACTTTTCTTGTACGGTTCCCAGGCCCCAAAATCCAGCCAGTGAGATT
ACTTTCCAGTGCATCAATTATGGGTCAGCTCAAAAGTTGAATTTTAACAGACCACAAAAGTCTT
CACCTGCTTTAAATCTGGGCACATTGTTACTTAACTGCTCCCCTCCCCCATATACACTCTATCT
TTAGCCATTTCTCACAAGTGCATTTGGTAATGACCGGGGGAGGGGGGAATGAATGCGCTTTTGT
AAAGCTATTTCCATACCTACGTTGGAATATTCTTGTAGATTCCAAAACCCAAACGCTTCATCTC
TCTTTAAATACATTAGAGGAGTCTCTTTTTTCTTTTTTTTTTTTCTTTAATTACGTCGGGAGGG
GATCATATGTTGGCAAGATCAGAGGACAACTTGTAGGAGTCAGTTCTCTCCTTTCCACTAAGTT
GACCCTGGTAACGACACATTAAAATTCTAGAAGCT

hide sequence

Protein Sequences


GenBank Protein	AAC27528	(Get FASTA)	NCBI Sequence Viewer

Additional Information

External Database Links

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-47498	BioCyc
NCBI Gene	246151	ENTREZGENE
PhenoGen	Sert1	PhenoGen
RNAcentral	URS00007E4320	RNACentral

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2002-08-07	Sert1	Sertoli cell protein 1			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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