Cetn3 (centrin 3) - Rat Genome Database

Name: Cetn3
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Cetn3 (centrin 3) Rattus norvegicus

Analyze

Symbol:

Cetn3

Name:

centrin 3

RGD ID:

620249

Description:

Predicted to enable G-protein beta/gamma-subunit complex binding activity; calcium ion binding activity; and microtubule binding activity. Predicted to be located in microtubule organizing center and photoreceptor connecting cilium. Predicted to be part of nuclear pore nuclear basket and transcription export complex 2. Predicted to be active in microtubule organizing center. Orthologous to human CETN3 (centrin 3); INTERACTS WITH 17beta-estradiol; 2,4-dinitrotoluene; 2,6-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

centrin, EF-hand protein, 3; centrin, EF-hand protein, 3 (CDC31 homolog, yeast); centrin-3; centrin-3-like; LOC100912538

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CETN3 (centrin 3)	HGNC	Ensembl, Inparanoid, OMA, OrthoDB, Panther
Mus musculus (house mouse):	Cetn3 (centrin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Cetn3 (centrin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CETN3 (centrin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CETN3 (centrin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Cetn3 (centrin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CETN3 (centrin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	CETN3 (centrin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Cetn3 (centrin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	FAM124A (family with sequence similarity 124 member A)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	CETN3 (centrin 3)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Cetn3 (centrin 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	cetn3 (centrin 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	CDC31	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	cetn3	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	13,817,760 - 13,837,502 (+)	NCBI		GRCr8
mRatBN7.2	2	12,089,025 - 12,101,828 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	12,089,226 - 12,101,828 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	19,202,033 - 19,214,399 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	17,301,555 - 17,313,921 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	11,958,922 - 11,971,333 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	12,101,473 - 12,115,009 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	12,102,487 - 12,115,009 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0 Ensembl	2	9,683,570 - 9,696,050 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	11,965,387 - 11,977,798 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	9,909,950 - 9,922,361 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	9,835,782 - 9,846,214 (+)	NCBI
Celera	2	8,442,073 - 8,454,484 (+)	NCBI		Celera
Cytogenetic Map	2	q11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

familial adenomatous polyposis 1 (ISO)

genetic disease (ISO)

Hereditary Neoplastic Syndromes (ISO)

Neurodevelopmental Disorders (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

(S)-nicotine (ISO)

1,2-dimethylhydrazine (ISO)

1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4-dinitrotoluene (EXP)

2,6-dinitrotoluene (EXP)

2-methylcholine (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

5-aza-2'-deoxycytidine (ISO)

acrolein (ISO)

aflatoxin B1 (ISO)

aflatoxin M1 (ISO)

alpha-pinene (ISO)

ammonium chloride (EXP)

antimycin A (ISO)

arsenite(3-) (ISO)

azoxystrobin (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP)

caffeine (ISO)

CGP 52608 (ISO)

choline (ISO)

chromium(6+) (ISO)

cisplatin (ISO)

cobalt dichloride (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

deguelin (ISO)

dexamethasone (ISO)

dibutyl phthalate (ISO)

dicrotophos (ISO)

epoxiconazole (ISO)

ethanol (ISO)

folic acid (ISO)

folpet (ISO)

indometacin (ISO)

L-methionine (ISO)

methylmercury chloride (ISO)

methylparaben (ISO)

nicotine (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

paraquat (ISO)

perfluorooctane-1-sulfonic acid (ISO)

potassium chromate (ISO)

testosterone (EXP)

tungsten (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

microtubule cytoskeleton organization (IBA)

Cellular Component

centriole (ISO)

centrosome (IEA,ISO)

ciliary basal body (ISO)

ciliary transition zone (ISO)

microtubule organizing center (IBA)

nuclear pore nuclear basket (ISO)

photoreceptor connecting cilium (ISO)

transcription export complex 2 (ISO)

Molecular Function

calcium ion binding (IBA)

G-protein beta/gamma-subunit complex binding (ISO)

microtubule binding (IBA,ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	A role for centrin 3 in centrosome reproduction.	Middendorp S, etal., J Cell Biol 2000 Feb 7;148(3):405-16.
5.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
6.	GOA pipeline	RGD automated data pipeline
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12802058	PMID:15347651	PMID:18269917	PMID:18762898	PMID:21399614	PMID:22031837	PMID:23591820	PMID:24833722	PMID:26337392

Genomics

Comparative Map Data

Cetn3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	13,817,760 - 13,837,502 (+)	NCBI		GRCr8
mRatBN7.2	2	12,089,025 - 12,101,828 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	12,089,226 - 12,101,828 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	19,202,033 - 19,214,399 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	17,301,555 - 17,313,921 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	11,958,922 - 11,971,333 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	12,101,473 - 12,115,009 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	12,102,487 - 12,115,009 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0 Ensembl	2	9,683,570 - 9,696,050 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	11,965,387 - 11,977,798 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	9,909,950 - 9,922,361 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	9,835,782 - 9,846,214 (+)	NCBI
Celera	2	8,442,073 - 8,454,484 (+)	NCBI		Celera
Cytogenetic Map	2	q11	NCBI

CETN3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	90,392,257 - 90,409,756 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	90,392,257 - 90,409,766 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	89,688,074 - 89,705,573 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	89,725,284 - 89,741,359 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	5	89,725,286 - 89,741,359	NCBI
Celera	5	85,591,376 - 85,607,451 (-)	NCBI		Celera
Cytogenetic Map	5	q14.3	NCBI
HuRef	5	84,900,167 - 84,916,242 (-)	NCBI		HuRef
CHM1_1	5	89,122,207 - 89,138,285 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	5	90,878,812 - 90,896,306 (-)	NCBI		T2T-CHM13v2.0

Cetn3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	81,928,201 - 81,945,274 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	81,931,196 - 81,945,274 (+)	Ensembl		GRCm39 Ensembl
GRCm38	13	81,780,636 - 81,797,155 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	81,783,077 - 81,797,155 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	13	81,922,291 - 81,936,156 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	13	82,260,629 - 82,274,494 (+)	NCBI		MGSCv36	mm8
Celera	13	84,040,605 - 84,054,471 (+)	NCBI		Celera
Cytogenetic Map	13	C3	NCBI
cM Map	13	43.68	NCBI

Cetn3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955418	21,206,387 - 21,222,456 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955418	21,206,387 - 21,220,984 (+)	NCBI	ChiLan1.0	ChiLan1.0

CETN3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	24,989,521 - 25,005,413 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	23,143,141 - 23,159,033 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	24,965,172 - 24,981,259 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	25,098,973 - 25,114,676 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	25,098,973 - 25,114,676 (+)	Ensembl	panpan1.1		panPan2

CETN3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	3	18,529,198 - 18,547,195 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	3	18,529,240 - 18,547,069 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	3	19,896,446 - 19,915,446 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	3	18,433,800 - 18,452,784 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	3	18,433,834 - 18,453,058 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	3	18,408,918 - 18,427,898 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	3	18,374,708 - 18,393,706 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	3	18,663,156 - 18,682,119 (+)	NCBI		UU_Cfam_GSD_1.0

Cetn3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	174,109,017 - 174,124,187 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936469	8,501,552 - 8,516,927 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936469	8,501,572 - 8,516,722 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CETN3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	97,572,449 - 97,593,291 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	97,574,003 - 97,593,320 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	100,651,981 - 100,671,290 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CETN3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	4	84,334,503 - 84,350,269 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	4	84,334,533 - 84,350,276 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666049	33,392,231 - 33,407,996 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cetn3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624743	9,661,857 - 9,677,599 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624743	9,663,281 - 9,677,626 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Cetn3
63 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	478
Count of miRNA genes:	159
Interacting mature miRNAs:	181
Transcripts:	ENSRNOT00000072155, ENSRNOT00000074157
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631682	Bp115	Blood pressure QTL 115	4.3	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	1	37410502	Rat
738010	Lnnr3	Liver neoplastic nodule remodeling QTL 3	2.94		liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number (CMO:0001461)	2	1	41244106	Rat
61355	Bp36	Blood pressure QTL 36	2.9		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	2	5873687	102844969	Rat
731166	Mamtr2	Mammary tumor resistance QTL 2		0.0001	mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	2	7887772	12654247	Rat
61368	Mcs1	Mammary carcinoma susceptibility QTL 1	4.4		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	2	7887772	23319447	Rat
1600379	Mcs18	Mammary carcinoma susceptibility QTL 18	2.6		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	2	7887772	42804738	Rat
738012	Anxrr3	Anxiety related response QTL 3	3.8		exploratory behavior trait (VT:0010471)	percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)	2	9023519	54023519	Rat
10755430	Coatc6	Coat color QTL 6		0.02576	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	2	11591100	56591100	Rat
1578664	Bmd9	Bone mineral QTL density 9	5		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	2	11852062	49003364	Rat

Markers in Region

AI030566

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	12,101,526 - 12,101,616 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	12,114,708 - 12,114,797	NCBI	Rnor6.0
Rnor_6.0	2	9,695,791 - 9,695,880	NCBI	Rnor6.0
Rnor_5.0	2	11,977,497 - 11,977,586	UniSTS	Rnor5.0
Rnor_5.0	2	9,574,021 - 9,574,110	UniSTS	Rnor5.0
RGSC_v3.4	2	9,922,060 - 9,922,149	UniSTS	RGSC3.4
Celera	2	8,454,183 - 8,454,272	UniSTS
Cytogenetic Map	2	q11	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium
Low	1	22	12	6	10	6			59	27	40	10
Below cutoff	2	19	40	30	9	30	6	7	15	8	1	1	6

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001191842	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101606	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281214	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281215	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_590796	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF335277	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473955	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ234873	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000072155 ⟹ ENSRNOP00000067453

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	12,089,427 - 12,101,718 (+)	Ensembl
Rnor_6.0 Ensembl	2	12,102,598 - 12,115,009 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000074157 ⟹ ENSRNOP00000064372

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	12,089,226 - 12,101,828 (+)	Ensembl
Rnor_6.0 Ensembl	2	9,683,570 - 9,696,050 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000089209 ⟹ ENSRNOP00000068650

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	2	12,102,487 - 12,112,917 (+)	Ensembl

RefSeq Acc Id:

NM_001191842 ⟹ NP_001178771

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	13,825,091 - 13,837,502 (+)	NCBI
mRatBN7.2	2	12,089,417 - 12,101,828 (+)	NCBI
Rnor_6.0	2	12,102,598 - 12,115,009 (+)	NCBI
Rnor_5.0	2	11,965,387 - 11,977,798 (+)	NCBI
Celera	2	8,442,073 - 8,454,484 (+)	NCBI

Sequence:

show sequence

GGTGGTCCCCGAGGCCGTGGAGGTTGGTGGCTGTTGAGCGGTTCTCGTGGTAAAGTCCTTGAGC
GGAACACCTCTGTCGGAAGAGAAAATGAGTTTAGCTCTGAGAGGTGAGCTTGTAGTAGACAAAA
CAAAAAGGAAAAAACGAAGAGAACTCTCTGAAGAACAGAAGCAAGAAATTAAAGATGCTTTTGA
ACTGTTTGATACCGACAAAGACCAAGCCATAGATTATCATGAATTAAAGGTGGCAATGAGAGCC
TTGGGTTTTGATGTGAAAAAGGCGGATGTATTGAAGATTCTTAAAGATTATGACAGAGAAGCCA
CAGGCAAGATCACATTTGAAGATTTTAATGAAGTTGTGACAGACTGGATACTAGAAAGAGATCC
ACACGAGGAGATCCTGAAAGCATTTAAACTATTTGATGATGATGATTCAGGAAAGATAAGCTTG
AGGAACTTGCGCCGTGTTGCCCGAGAGCTGGGTGAGAATATGAGCGATGAGGAGCTCCGGGCCA
TGATCGAGGAGTTTGATAAGGACGGCGATGGGGAGATAAATCAAGAGGAATTCATTGCTATTAT
GACTGGTGACATATAAAGAATTACAAGACTGAACACCAAAATGTTGTGGTTACCATCTCTCTTC
TCTTTGTGTGCCTGGAGCCCTGTTTAAGAAAACAAAACAAAACAATCCAACCTAGTTCTTTTTC
TGAAAGGAACAAACCAAGCATCCTTTGTATGTATATTTCAATACTGTTAAGTTTATGTCATCAA
TGTAGTAGTTGACTTCACATTTATAATACATGTTTATATAAAGCTTTAAAACATCAAATCATGT
GGTGTATATTATTTGGAGGCTTCTAAATTTATCATTAGTTAATTGCTTTTATTTTCATGCACAG
TTTTTAGATATTTATTAATAAAATACTTATTTTATTAGTA

hide sequence

RefSeq Acc Id:

XM_039101606 ⟹ XP_038957534

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	13,817,760 - 13,837,392 (+)	NCBI
mRatBN7.2	2	12,089,058 - 12,101,828 (+)	NCBI

RefSeq Acc Id:

XM_063281214 ⟹ XP_063137284

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	13,817,760 - 13,835,398 (+)	NCBI

RefSeq Acc Id:

XM_063281215 ⟹ XP_063137285

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	13,825,066 - 13,835,366 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001178771	(Get FASTA)	NCBI Sequence Viewer
	XP_038957534	(Get FASTA)	NCBI Sequence Viewer
	XP_063137284	(Get FASTA)	NCBI Sequence Viewer
	XP_063137285	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAK83217	(Get FASTA)	NCBI Sequence Viewer
	EDM09950	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000064372
	ENSRNOP00000064372.2
	ENSRNOP00000067453
	ENSRNOP00000067453.2

RefSeq Acc Id:	NP_001178771 ⟸ NM_001191842
- UniProtKB:	A6I4J2 (UniProtKB/TrEMBL), Q91ZZ8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSLALRGELVVDKTKRKKRRELSEEQKQEIKDAFELFDTDKDQAIDYHELKVAMRALGFDVKKA DVLKILKDYDREATGKITFEDFNEVVTDWILERDPHEEILKAFKLFDDDDSGKISLRNLRRVAR ELGENMSDEELRAMIEEFDKDGDGEINQEEFIAIMTGDI hide sequence

RefSeq Acc Id:

ENSRNOP00000068650 ⟸ ENSRNOT00000089209

RefSeq Acc Id:

ENSRNOP00000067453 ⟸ ENSRNOT00000072155

RefSeq Acc Id:	XP_038957534 ⟸ XM_039101606
- Peptide Label:	isoform X2
- UniProtKB:	G3V821 (UniProtKB/TrEMBL), Q91ZZ8 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSRNOP00000064372 ⟸ ENSRNOT00000074157

RefSeq Acc Id:	XP_063137284 ⟸ XM_063281214
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_063137285 ⟸ XM_063281215
- Peptide Label:	isoform X3

Protein Domains

EF-hand

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A0G2JTC2-F1-model_v2	AlphaFold	A0A0G2JTC2	1-177	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13691048

Promoter ID:

EPDNEW_R1573

Type:

initiation region

Name:

Cetn3_1

Description:

centrin 3

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	2	12,102,590 - 12,102,650	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620249	AgrOrtholog
BioCyc Gene	G2FUF-55012	BioCyc
Ensembl Genes	ENSRNOG00000048563	Ensembl
	ENSRNOG00000050877	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000072155	ENTREZGENE
	ENSRNOT00000072155.2	UniProtKB/TrEMBL
	ENSRNOT00000074157.3	UniProtKB/TrEMBL
Gene3D-CATH	EF-hand	UniProtKB/TrEMBL
InterPro	EF-hand-like_dom	UniProtKB/TrEMBL
	EF_Hand_1_Ca_BS	UniProtKB/TrEMBL
	EF_hand_Ca-bd	UniProtKB/TrEMBL
KEGG Report	rno:170895	UniProtKB/TrEMBL
NCBI Gene	170895	ENTREZGENE
PANTHER	CALCIUM BINDING PROTEIN	UniProtKB/TrEMBL
	CENTRIN-3	UniProtKB/TrEMBL
Pfam	EF_hand_5	UniProtKB/TrEMBL
PhenoGen	Cetn3	PhenoGen
PROSITE	EF_HAND_1	UniProtKB/TrEMBL
	EF_HAND_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000048563	RatGTEx
	ENSRNOG00000050877	RatGTEx
SMART	EFh	UniProtKB/TrEMBL
Superfamily-SCOP	SSF47473	UniProtKB/TrEMBL
UniProt	A6I4J2	ENTREZGENE, UniProtKB/TrEMBL
	G3V821	ENTREZGENE, UniProtKB/TrEMBL
	M0RCW6_RAT	UniProtKB/TrEMBL
	Q91ZZ8	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Cetn3	centrin 3	LOC100912538	centrin-3-like	Data merged from RGD:6486167	737654	PROVISIONAL
2015-12-09	Cetn3	centrin 3	Cetn3	centrin, EF-hand protein, 3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2012-07-05	LOC100912538	centrin-3-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2011-08-01	Cetn3	centrin, EF-hand protein, 3	Cetn3	centrin, EF-hand protein, 3 (CDC31 homolog, yeast)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2010-02-04	Cetn3	centrin, EF-hand protein, 3 (CDC31 homolog, yeast)	Cetn3	centrin 3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-20	Cetn3	centrin 3		centrin, EF-hand protein, 3 (CDC31 homolog, yeast)	Name updated	1299863	APPROVED
2002-08-07	Cetn3	centrin, EF-hand protein, 3 (CDC31 homolog, yeast)			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_homology	human homolog has similarity to S. cerevisiae CDC31, which is involved in spinal pole body duplication	635268

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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