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Gene: Sh3bp5 (SH3-domain binding protein 5) Rattus norvegicus

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Symbol:

Sh3bp5 (Ensembl: Mettl6)

Name:

SH3-domain binding protein 5 (Ensembl:methyltransferase 6, tRNA N3-cytidine)

RGD ID:

620220

Description:

Predicted to enable guanyl-nucleotide exchange factor activity and protein kinase inhibitor activity. Predicted to be involved in intracellular signal transduction. Located in mitochondrion. Orthologous to human SH3BP5 (SH3 domain binding protein 5); INTERACTS WITH (+)-schisandrin B; 1,3,5-trinitro-1,3,5-triazinane; 17alpha-ethynylestradiol.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

Sab; SH3 domain-binding protein 5; SH3-domain binding protein 5 (BTK-associated); SH3BP-5; vascular endothelial cell-specific protein 18; Vesp18

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SH3BP5 (SH3 domain binding protein 5)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, Panther, PhylomeDB
Mus musculus (house mouse):	Sh3bp5 (SH3-domain binding protein 5 (BTK-associated))	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Sh3bp5 (SH3 domain binding protein 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SH3BP5 (SH3 domain binding protein 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SH3BP5 (SH3 domain binding protein 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Sh3bp5 (SH3 domain binding protein 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SH3BP5 (SH3 domain binding protein 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SH3BP5 (SH3 domain binding protein 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Sh3bp5 (SH3 domain binding protein 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Sh3bp5 (SH3 domain binding protein 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	METTL6 (methyltransferase 6, tRNA N3-cytidine)	HGNC	Inparanoid, PhylomeDB
Alliance orthologs ³
Homo sapiens (human):	SH3BP5 (SH3 domain binding protein 5)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	SH3BP5 (SH3 domain binding protein 5)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Sh3bp5 (SH3-domain binding protein 5 (BTK-associated))	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	sh3bp5b (SH3-domain binding protein 5b (BTK-associated))	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	rei-1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Caenorhabditis elegans (roundworm):	rei-2	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	rei-2	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	pcs	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	pcs	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	sh3bp5	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	sh3bp5	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	6,589,877 - 6,676,524 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	16	6,589,877 - 6,655,211 (-)	Ensembl				GRCr8
mRatBN7.2	16	6,583,462 - 6,678,344 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	6,583,465 - 6,698,975 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	16	6,595,768 - 6,660,252 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	7,740,664 - 7,805,146 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	6,602,675 - 6,667,565 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	7,473,367 - 7,559,976 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	7,473,370 - 7,538,201 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	16	7,408,996 - 7,472,907 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	16	6,822,512 - 6,888,922 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	16	8,541,799 - 8,606,037 (+)	NCBI		Celera
RGSC_v3.1	16	6,822,512 - 6,888,920 (-)	NCBI
Cytogenetic Map	16	p16	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,2-dichloroethane (ISO)

1,3,5-trinitro-1,3,5-triazinane (EXP)

17alpha-ethynylestradiol (EXP,ISO)

17beta-estradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

2-palmitoylglycerol (ISO)

3,3',4,4',5-pentachlorobiphenyl (EXP)

3,4-methylenedioxymethamphetamine (EXP)

3-chloropropane-1,2-diol (EXP)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-diaminodiphenylmethane (ISO)

4-hydroxyphenyl retinamide (ISO)

8-Br-cAMP (ISO)

acrylamide (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

Ampullosporin (EXP)

Aroclor 1254 (ISO)

arotinoid acid (ISO)

Bardoxolone methyl (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

benzo[e]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

buspirone (EXP)

buta-1,3-diene (ISO)

butanal (ISO)

Butylbenzyl phthalate (ISO)

cadmium dichloride (EXP,ISO)

capsaicin (EXP)

carbamazepine (ISO)

carbon nanotube (ISO)

CHIR 99021 (ISO)

chloroprene (ISO)

cisplatin (ISO)

clofibrate (ISO)

cobalt dichloride (EXP,ISO)

cortisol (ISO)

cyclosporin A (ISO)

dexamethasone (ISO)

dibutyl phthalate (ISO)

diethyl maleate (ISO)

diethyl phthalate (ISO)

diisobutyl phthalate (ISO)

diisononyl phthalate (ISO)

dioxygen (EXP,ISO)

disodium selenite (ISO)

diuron (EXP)

dorsomorphin (ISO)

epoxiconazole (ISO)

ethanol (ISO)

fipronil (EXP)

flutamide (EXP)

furan (EXP)

glafenine (EXP)

indometacin (ISO)

ketamine (EXP)

L-ascorbic acid (ISO)

L-ascorbic acid 2-phosphate (ISO)

leflunomide (EXP)

levofloxacin (EXP)

metformin (EXP)

methapyrilene (EXP,ISO)

methylseleninic acid (ISO)

mitomycin C (ISO)

mono(2-ethylhexyl) phthalate (ISO)

monobenzyl phthalate (ISO)

Monobutylphthalate (ISO)

monoethyl phthalate (ISO)

N-Nitrosopyrrolidine (ISO)

nitrates (ISO)

okadaic acid (ISO)

oxaliplatin (EXP)

ozone (ISO)

paracetamol (EXP,ISO)

perfluorohexanesulfonic acid (ISO)

perfluorononanoic acid (ISO)

phenobarbital (ISO)

phenylmercury acetate (ISO)

propiconazole (ISO)

resveratrol (ISO)

rotenone (EXP)

SB 431542 (ISO)

senecionine (ISO)

silicon dioxide (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

tauroursodeoxycholic acid (EXP)

Tesaglitazar (EXP)

tetrachloromethane (EXP,ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

topotecan (EXP)

triphenyl phosphate (ISO)

triptonide (ISO)

troglitazone (ISO)

trovafloxacin (EXP)

urethane (ISO)

valproic acid (ISO)

XAV939 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

intracellular signal transduction (IBA,IEA,ISO)

JNK cascade (NAS)

negative regulation of protein kinase activity (ISO)

Cellular Component

cytoplasm (IBA,IEA)

cytoplasmic vesicle (IEA)

cytoplasmic vesicle membrane (IEA,ISO)

mitochondrion (IDA,IEA)

nuclear body (IEA,ISO)

nucleoplasm (IEA,ISO)

Molecular Function

guanyl-nucleotide exchange factor activity (IEA,ISO,ISS)

protein binding (IPI,ISO)

protein kinase inhibitor activity (IBA,IEA,ISO)

SH3 domain binding (IEA,TAS)

References

References - curated

#	Reference Title	Reference Citation
1.	Phosphorylation of the mitochondrial protein Sab by stress-activated protein kinase 3.	Court NW, etal., Biochem Biophys Res Commun. 2004 Jun 18;319(1):130-7.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
7.	A new c-Jun N-terminal kinase (JNK)-interacting protein, Sab (SH3BP5), associates with mitochondria.	Wiltshire C, etal., Biochem J 2002 Nov 1;367(Pt 3):577-85.

Additional References at PubMed

PMID:10339589	PMID:30217979

Genomics

Comparative Map Data

Sh3bp5
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	6,589,877 - 6,676,524 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	16	6,589,877 - 6,655,211 (-)	Ensembl				GRCr8
mRatBN7.2	16	6,583,462 - 6,678,344 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	6,583,465 - 6,698,975 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	16	6,595,768 - 6,660,252 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	7,740,664 - 7,805,146 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	6,602,675 - 6,667,565 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	7,473,367 - 7,559,976 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	7,473,370 - 7,538,201 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	16	7,408,996 - 7,472,907 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	16	6,822,512 - 6,888,922 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	16	8,541,799 - 8,606,037 (+)	NCBI		Celera
RGSC_v3.1	16	6,822,512 - 6,888,920 (-)	NCBI
Cytogenetic Map	16	p16	NCBI

SH3BP5
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	15,254,353 - 15,341,380 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	15,254,353 - 15,341,368 (-)	Ensembl			hg38	GRCh38
GRCh37	3	15,295,860 - 15,382,887 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	15,271,361 - 15,357,905 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	3	15,271,367 - 15,348,892	NCBI
Celera	3	15,234,616 - 15,321,139 (-)	NCBI		Celera
Cytogenetic Map	3	p25.1	NCBI
HuRef	3	15,231,318 - 15,318,336 (-)	NCBI		HuRef
CHM1_1	3	15,246,746 - 15,333,790 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	3	15,256,759 - 15,343,784 (-)	NCBI		T2T-CHM13v2.0

Sh3bp5
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	31,094,571 - 31,158,056 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	31,081,837 - 31,158,035 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	14	31,372,614 - 31,436,100 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	31,359,880 - 31,436,078 (-)	Ensembl			mm10	GRCm38
MGSCv37	14	32,187,141 - 32,249,219 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	14	30,203,993 - 30,264,870 (-)	NCBI		MGSCv36	mm8
Celera	14	27,632,639 - 27,694,829 (-)	NCBI		Celera
Cytogenetic Map	14	B	NCBI
cM Map	14	19.11	NCBI

Sh3bp5
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955430	2,196,967 - 2,264,953 (+)	Ensembl
ChiLan1.0	NW_004955430	2,251,544 - 2,266,166 (+)	NCBI	ChiLan1.0	ChiLan1.0

SH3BP5
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	15,239,521 - 15,317,375 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	15,244,282 - 15,321,989 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	15,180,369 - 15,257,951 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	15,517,447 - 15,594,971 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	15,517,447 - 15,594,971 (-)	Ensembl			panPan2	panpan1.1

SH3BP5
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	23	27,258,502 - 27,335,175 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	23	27,202,875 - 27,334,010 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	23	27,232,632 - 27,309,150 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	23	27,770,472 - 27,847,079 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	23	27,715,728 - 27,847,075 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	23	27,460,017 - 27,536,480 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	23	27,521,691 - 27,598,215 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	23	27,770,953 - 27,847,541 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Sh3bp5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	169,965,168 - 169,971,857 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936473	3,038,963 - 3,109,174 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936473	3,103,878 - 3,110,435 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SH3BP5
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	2,506,156 - 2,585,526 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	13	2,504,282 - 2,585,601 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	2,433,078 - 2,512,617 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SH3BP5
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	15	60,098,901 - 60,175,421 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	15	60,100,132 - 60,175,349 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666041	33,128,495 - 33,204,981 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Sh3bp5
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624822	4,950,735 - 5,021,337 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624822	4,950,735 - 5,021,233 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Sh3bp5
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	13	7,092,509 - 7,158,211 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Sh3bp5
822 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	495
Count of miRNA genes:	254
Interacting mature miRNAs:	314
Transcripts:	ENSRNOT00000026389
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1582235	Insul8	Insulin level QTL 8	3.3	0.0063	blood insulin amount (VT:0001560)	calculated serum insulin level (CMO:0000359)	16	4234212	16278352	Rat
1549842	Bp248	Blood pressure QTL 248		0.01	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	16	387123	45387123	Rat
2307172	Activ4	Activity QTL 4	3.71	0.00023	locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	16	1	33425095	Rat
1354584	Despr6	Despair related QTL 6	3.1	0.0067	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	16	1	39568015	Rat
737819	Hcas4	Hepatocarcinoma susceptibility QTL 4	4.43		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	16	4234212	53708481	Rat
1354625	Despr7	Despair related QTL 7	3.16	0.016	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	16	4744222	49744222	Rat
61338	Bp23	Blood pressure QTL 23	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	16	4234212	16278352	Rat
61405	Niddm6	Non-insulin dependent diabetes mellitus QTL 6	3.66	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	16	1	26734272	Rat
631830	Alc7	Alcohol consumption QTL 7	2.9		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	16	1	26734272	Rat
7411664	Foco30	Food consumption QTL 30	11	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	16	4354822	49354822	Rat
1600378	Arunc4	Aerobic running capacity QTL 4		0.03	exercise endurance trait (VT:0002332)	longest distance run on treadmill (CMO:0001406)	16	387123	45387123	Rat
70183	BpQTLcluster13	Blood pressure QTL cluster 13	3.654		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	16	4234212	49757901	Rat
737826	Alc11	Alcohol consumption QTL 11	3.2		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	16	4234212	66955197	Rat
737825	Alc13	Alcohol consumption QTL 13	4.5		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	16	4234212	16061395	Rat
2303566	Bw90	Body weight QTL 90	2		body mass (VT:0001259)	body weight (CMO:0000012)	16	1	39568015	Rat
631524	Bp75	Blood pressure QTL 75		0.05	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	16	117710	8157035	Rat
2312663	Slep9	Serum leptin concentration QTL 9		0.001	blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	16	839086	66195506	Rat
2306902	Bp339	Blood pressure QTL 339		0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	16	3386790	49757901	Rat
1300133	Rf24	Renal function QTL 24	3.64		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	16	3386790	26128267	Rat
2312660	Bw95	Body weight QTL 95		0.05	inguinal fat pad mass (VT:0010424)	inguinal fat pad weight to body weight ratio (CMO:0001253)	16	839086	66195506	Rat
2312666	Insul16	Insulin level QTL 16		0.01	blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	16	839086	66195506	Rat
634355	Rends4	Renal damage susceptibility QTL 4		0.05	kidney blood vessel morphology trait (VT:0000530)	organ lesion measurement (CMO:0000677)	16	1	26734272	Rat
61372	Bp40	Blood pressure QTL 40	2.2		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	16	4234333	17730812	Rat
2293343	Glom16	Glomerulus QTL 16	7.4		kidney glomerulus integrity trait (VT:0010546)	kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)	16	839086	52786090	Rat
2312669	Stl23	Serum triglyceride level QTL 23		0.01	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	16	839086	66195506	Rat
6903319	Bw114	Body weight QTL 114	2.7	0.0037	body mass (VT:0001259)	body weight (CMO:0000012)	16	3301683	48301683	Rat

Markers in Region

D16Rat124

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	16	6,610,899 - 6,611,026 (+)	Marker Load Pipeline
mRatBN7.2	16	6,604,487 - 6,604,614 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	7,494,390 - 7,494,516	NCBI	Rnor6.0
Rnor_5.0	16	7,429,574 - 7,429,700	UniSTS	Rnor5.0
RGSC_v3.4	16	6,844,488 - 6,844,614	RGD	RGSC3.4
RGSC_v3.4	16	6,844,489 - 6,844,615	UniSTS	RGSC3.4
Celera	16	8,584,954 - 8,585,080	UniSTS
RGSC_v3.1	16	6,844,486 - 6,844,612	RGD
RH 3.4 Map	16	54.4	UniSTS
RH 3.4 Map	16	54.4	RGD
RH 2.0 Map	16	0.0	RGD
Cytogenetic Map	16	p16	UniSTS

BE107294

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	6,583,462 - 6,583,641 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	7,473,365 - 7,473,543	NCBI	Rnor6.0
Rnor_5.0	16	7,408,994 - 7,409,172	UniSTS	Rnor5.0
RGSC_v3.4	16	6,822,510 - 6,822,688	UniSTS	RGSC3.4
Celera	16	8,605,861 - 8,606,039	UniSTS
RH 3.4 Map	16	50.4	UniSTS
Cytogenetic Map	16	p16	UniSTS

SH3BP5

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	6,588,163 - 6,588,259 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	7,478,066 - 7,478,161	NCBI	Rnor6.0
Rnor_5.0	16	7,413,694 - 7,413,789	UniSTS	Rnor5.0
RGSC_v3.4	16	6,828,023 - 6,828,118	UniSTS	RGSC3.4
Celera	16	8,601,243 - 8,601,338	UniSTS
Cytogenetic Map	16	p16	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_054011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017599980	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017599981	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039094171	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039094172	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039094174	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063275045	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063275046	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB027562	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC099108	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474046	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ210473	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000082172 ⟹ ENSRNOP00000071111

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	16	6,589,877 - 6,655,211 (-)	Ensembl
mRatBN7.2 Ensembl	16	6,583,465 - 6,648,399 (-)	Ensembl
Rnor_6.0 Ensembl	16	7,473,370 - 7,538,201 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000084645 ⟹ ENSRNOP00000074466

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	16	6,682,837 - 6,698,975 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000098759 ⟹ ENSRNOP00000088603

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	16	6,583,465 - 6,652,738 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000103715 ⟹ ENSRNOP00000081006

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	16	6,589,877 - 6,635,808 (-)	Ensembl
mRatBN7.2 Ensembl	16	6,583,465 - 6,629,398 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000104042 ⟹ ENSRNOP00000086596

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	16	6,682,834 - 6,697,749 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000110815 ⟹ ENSRNOP00000078582

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	16	6,589,877 - 6,655,211 (-)	Ensembl
mRatBN7.2 Ensembl	16	6,583,465 - 6,698,975 (-)	Ensembl

RefSeq Acc Id:

NM_054011 ⟹ NP_446463

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	6,589,877 - 6,654,711 (-)	NCBI
mRatBN7.2	16	6,583,465 - 6,648,301 (-)	NCBI
Rnor_6.0	16	7,473,367 - 7,538,201 (-)	NCBI
Rnor_5.0	16	7,408,996 - 7,472,907 (-)	NCBI
RGSC_v3.4	16	6,822,512 - 6,888,922 (-)	RGD
Celera	16	8,541,799 - 8,606,037 (+)	RGD

Sequence:

show sequence

GCATGGACACGGCGCTGAAACGGAGCCGCTCTGAGGAGCCGGTGGAGCTCCCGCCGCCCGCCCG
GGAGGCGGAGGAGAAAGAGGAGGAGGAAGAGAGGATGGAACAGGGCCTGGAGGAGGAGGAAGAG
GTGGACCCCCGGATCCAGGGAGAACTGGAGAAGTTAAATCAATCCACCGATGACATCAACAGAC
GGGAGACTGAACTTGAGGATGCACGCCAGAAATTCCGGTCTGTCCTGGTTGAGGCGACGGTGAA
ACTTGACGAGCTGGCGAAGAAAATCGGCAAGGCTGTAGAGGACTCGAAGCCCTACTGGGAGGCC
CGCAGGGTGGCAAGGCAGGCTCAGCTAGAAGCGCAGAAAGCCACACAGGACTTCCAGAGGGCTA
CTGAGGTGCTCCGTGCAGCCAAGGAGACAATCTCCCTGGCCGAGCAGCGGCTGCTGGAGGATGA
CAAGCGCCAGTTTGACTCTGCTTGGCAGGAAATGCTGAATCACGCTACTCAGAGGGTCATGGAG
GCTGAGCAGACCAAGACACGGAGCGAGCTGGTGCACAAGGAGACAGCGGCCAGGTACAATGCCG
CCATGGGCCGCATGCGGCAGCTGGAGAAGAAACTCAAGCGAGCCATCAACAAGTCCAAGCCTTA
TTTTGAGCTAAAGGCCAAGTACTACGTGCAGCTCGAGCAACTGAAGAAGACAGTGGATGACCTT
CAGGCCAAGCTGGCCCTGGCGAAAGGCGAGTATAAGGCAGCCCTGAAGAGCCTGGAGAGGATCT
CGGATGAGATACACGAGCGGCGGCGCTCCAATGCCATGGGGCCTCGGGGCTGTGGCGTGGGGGC
AGAGGGCAGCATCACCTCAGTGGAGAACCTGCCTGCAAGCAAGCCTGAGCCTGATGCCATTTCC
GTGGCTTCAGAAGCCTTTGAAGATGACAACTGCGGCAACTTGGTGTCTGAAGATGACTCAGAAA
CCCAGTCTGTGTCCAGCTTTAGTTCAGGACCAACAAGTCCATCTGAAATGCCTGACCAGTTCCC
TGCAGTGGCAAGGCCCGGCAGCCTGGATCTGCCCAGCCCTGTGTCCCTGTCAGAATTTGGGATG
ATGTTCCCAATACTGGGTCCTCGAAGTGAATGCAGCGGGGCCTCCTCCCCTGAATGTGAGGTGG
AACGAGGAGACAGAGCAGAAGGGGCCGAGAATAAAATGAGTGACAAAGCCAACAACAACCGCGT
TCTCAGCAGCACCAGCGCTGGCGGTGGCAGGAGCAGGAGCCAAAGCAGCACATCCCTCGAGGGT
CAGGCCTTGGAAACCCGTATGAAGCAGCTCTCCCTACAGTGCTCAAAAGGAAGAGAAGGAATAA
TTGCTGACATAAAAACGGTGCAGATTGGCTGATCCACCCGGGGCTGTGGCCCATGTGCAGCTCG
TATTTATACACGAAATCCAAGAACATTGTGCCAATAATCATTTAACATAAGCCAAATAGTACGC
ACTTACTCTAGACCACACTAACAAGTTTCAGTGACCTTGAGGGCCAAGCAATGTCCCCCTGGTA
AGAGCTCTTGGGCTGGTGCGTTTTTCAGAGCAGAGCCACTGCAGGTAAACTGTGCCCAGGGCCA
CGGCCTTGGCAGAGCCTTCCCTGTGGAAGCAATAACTAGTTTCTGTGAGAGAACCTGAGCCGGG
AGAGCCGGGCACGTAGCCAGACTGGGTCACAGCCTGCATCTCTATCCCTGTGTCCCCTCCACCT
GGGGAAACTGAGATGATTTTGACATCACATCACAGGGCACCAAAATAATTTAAAAACTTACATA
AACAAAAACTCAAGTGTTCCGAACACATTGTAACAACAATGCCAGGGACACAGTTCACTATCAT
CGCCTCTGGTGCTCAGAGGGGTTAAGGAGCATGTCTTCTGGGAAACCGTTGAACCATTTCCTAG
GGAAGCCACCATGAACTGCACTTTTTGGGGTGGGAACAGTGAATGCCAATGTGGGGATGGGGAA
TGAAGTAGCGGGGACGTAGATAGCATAGACAGGATCTGCGGCTGGGGACGGTTTTATAGCCTGC
CCGCCAAGGGGCTTTATTCTAAGAGACGTGCATGTGAGGAATGATTACCACGGCTCTATCTAGA
TTGACAAGGAGTTCATTTCTCTGTAGACTGTAATTTCTACAATAACAGATTATTTAAGGTTTAT
GCTGCACCTAGAATTCCTTAGAGGAAACTGTCCTTGAAGCTAGGAAAGGGAGTGGGCATGGTTG
GTAAATAGAAGCAATGGATCTGTTATGCTAATAGTAGTGTCTAGACTTAGTGTTTCTGGTTATG
CATATTTAGAGCACTGTATTTTATGTGTCTTGTTTTATTAATCTACCGTTTCTGGAAAAAAAAA
AAACCAACCCGTTTCAAACTGCCTGTTAATGTTAGCCATGTATGTATACCTCTCTCTTCATACA
CGAGTGTTTCTCTTTTTTATTGATGGACACAGTATCCTTATTACAAGGTTATTTTGTACTTGTT
TTATTACCTGGAGTGTAATAAAAACTAAGAAGACTTTGTGACTTCCGATGAGAAAAAAAAAAAA
AAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039094171 ⟹ XP_038950099

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	6,589,877 - 6,654,820 (-)	NCBI
mRatBN7.2	16	6,583,462 - 6,648,528 (-)	NCBI

RefSeq Acc Id:

XM_039094172 ⟹ XP_038950100

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	6,589,877 - 6,604,090 (-)	NCBI
mRatBN7.2	16	6,583,462 - 6,597,714 (-)	NCBI

RefSeq Acc Id:

XM_039094174 ⟹ XP_038950102

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	6,589,877 - 6,676,524 (-)	NCBI
mRatBN7.2	16	6,583,462 - 6,670,101 (-)	NCBI

RefSeq Acc Id:

XM_063275045 ⟹ XP_063131115

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	6,589,877 - 6,629,492 (-)	NCBI

RefSeq Acc Id:

XM_063275046 ⟹ XP_063131116

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	6,589,877 - 6,651,760 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_446463	(Get FASTA)	NCBI Sequence Viewer
	XP_038950099	(Get FASTA)	NCBI Sequence Viewer
	XP_038950100	(Get FASTA)	NCBI Sequence Viewer
	XP_038950102	(Get FASTA)	NCBI Sequence Viewer
	XP_063131115	(Get FASTA)	NCBI Sequence Viewer
	XP_063131116	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	BAB47152	(Get FASTA)	NCBI Sequence Viewer
	EDL88950	(Get FASTA)	NCBI Sequence Viewer
	EDL88951	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000071111
	ENSRNOP00000078582
GenBank Protein	Q91Y80	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_446463 ⟸ NM_054011

- UniProtKB:

Q91Y80 (UniProtKB/Swiss-Prot), A6KFZ4 (UniProtKB/TrEMBL), A6KFZ3 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MDTALKRSRSEEPVELPPPAREAEEKEEEEERMEQGLEEEEEVDPRIQGELEKLNQSTDDINRR
ETELEDARQKFRSVLVEATVKLDELAKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDFQRAT
EVLRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHKETAARYNAA
MGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQAKLALAKGEYKAALKSLERIS
DEIHERRRSNAMGPRGCGVGAEGSITSVENLPASKPEPDAISVASEAFEDDNCGNLVSEDDSET
QSVSSFSSGPTSPSEMPDQFPAVARPGSLDLPSPVSLSEFGMMFPILGPRSECSGASSPECEVE
RGDRAEGAENKMSDKANNNRVLSSTSAGGGRSRSQSSTSLEGQALETRMKQLSLQCSKGREGII
ADIKTVQIG

hide sequence

Ensembl Acc Id:

ENSRNOP00000071111 ⟸ ENSRNOT00000082172

RefSeq Acc Id:	XP_038950102 ⟸ XM_039094174
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038950099 ⟸ XM_039094171
- Peptide Label:	isoform X1
- UniProtKB:	A0A8L2UQ41 (UniProtKB/TrEMBL), A6KFZ3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038950100 ⟸ XM_039094172
- Peptide Label:	isoform X2

Ensembl Acc Id:

ENSRNOP00000086596 ⟸ ENSRNOT00000104042

Ensembl Acc Id:

ENSRNOP00000074466 ⟸ ENSRNOT00000084645

Ensembl Acc Id:

ENSRNOP00000088603 ⟸ ENSRNOT00000098759

Ensembl Acc Id:

ENSRNOP00000078582 ⟸ ENSRNOT00000110815

Ensembl Acc Id:

ENSRNOP00000081006 ⟸ ENSRNOT00000103715

RefSeq Acc Id:	XP_063131116 ⟸ XM_063275046
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_063131115 ⟸ XM_063275045
- Peptide Label:	isoform X2

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q91Y80-F1-model_v2	AlphaFold	Q91Y80	1-457	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13699933

Promoter ID:

EPDNEW_R10456

Type:

initiation region

Name:

Sh3bp5_1

Description:

SH3-domain binding protein 5

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	16	7,538,277 - 7,538,337	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620220	AgrOrtholog
BioCyc Gene	G2FUF-12147	BioCyc
Ensembl Genes	ENSRNOG00000052391	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000082172	ENTREZGENE
	ENSRNOT00000110815	ENTREZGENE
InterPro	SH3BP5	UniProtKB/Swiss-Prot
KEGG Report	rno:117186	UniProtKB/Swiss-Prot
NCBI Gene	117186	ENTREZGENE
PANTHER	PTHR19423	UniProtKB/Swiss-Prot
	SH3 DOMAIN-BINDING PROTEIN 5	UniProtKB/Swiss-Prot
Pfam	SH3BP5	UniProtKB/Swiss-Prot
PhenoGen	Sh3bp5	PhenoGen
RatGTEx	ENSRNOG00000052391	RatGTEx
UniProt	3BP5_RAT	UniProtKB/Swiss-Prot
	A0A8I5ZL43_RAT	UniProtKB/TrEMBL
	A0A8I5ZS33_RAT	UniProtKB/TrEMBL
	A0A8L2UQ41	ENTREZGENE, UniProtKB/TrEMBL
	A6KFZ3	ENTREZGENE, UniProtKB/TrEMBL
	A6KFZ4	ENTREZGENE, UniProtKB/TrEMBL
	Q91Y80	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-03-16	Sh3bp5	SH3-domain binding protein 5	Sh3bp5	SH3-domain binding protein 5 (BTK-associated)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-09-10	Sh3bp5	SH3-domain binding protein 5 (BTK-associated)			Symbol and Name status set to approved	1299863	APPROVED
2002-08-07	Sh3bp5	SH3-domain binding protein 5 (BTK-associated)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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