Mmp24 (matrix metallopeptidase 24) - Rat Genome Database

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Gene: Mmp24 (matrix metallopeptidase 24) Rattus norvegicus
Analyze
Symbol: Mmp24
Name: matrix metallopeptidase 24
RGD ID: 620202
Description: Predicted to enable cadherin binding activity and metalloendopeptidase activity. Predicted to be involved in several processes, including cell-cell adhesion mediated by cadherin; collagen catabolic process; and detection of temperature stimulus involved in sensory perception of pain. Predicted to be located in trans-Golgi network membrane. Predicted to be active in extracellular space and plasma membrane. Orthologous to human MMP24 (matrix metallopeptidase 24); INTERACTS WITH (+)-schisandrin B; 1,3,5-trinitro-1,3,5-triazinane; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: matrix metalloproteinase 24 (membrane-inserted); matrix metalloproteinase-24; membrane-type matrix metalloproteinase 5; membrane-type-5 matrix metalloproteinase; MMP-24; MT-MMP 5; Mt5-mmp; MT5MMP; MTMMP5
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83164,739,226 - 164,783,696 (+)NCBIGRCr8
mRatBN7.23144,279,096 - 144,323,572 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3144,279,096 - 144,323,572 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3148,145,188 - 148,188,968 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03156,762,468 - 156,806,235 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03154,501,979 - 154,545,755 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03151,307,309 - 151,355,401 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3151,310,598 - 151,355,401 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03157,676,152 - 157,720,612 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera3143,019,816 - 143,047,813 (+)NCBICelera
Cytogenetic Map3q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mmp24Ratglutathione synthetase deficiency  ISOMMP24 (Homo sapiens)8554872ClinVar Annotator: match by term: PYROGLUTAMIC ACIDURIAClinVarPMID:12638941 more ...
Mmp24Ratglutatione synthetase deficiency with 5-oxoprolinuria  ISOMMP24 (Homo sapiens)8554872ClinVar Annotator: match by term: 5-OXOPROLINURIA DUE TO GLUTATHIONE SYNTHETASE DEFICIENCYClinVarPMID:12638941 more ...
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mmp24RatNeoplasm Metastasis  ISOMMP24 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:27869830

1 to 20 of 52 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mmp24Rat(+)-schisandrin B multiple interactionsEXP 6480464schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of MMP24 mRNA]CTDPMID:31150632
Mmp24Rat1,2-dichloroethane affects expressionISOMmp24 (Mus musculus)6480464ethylene dichloride affects the expression of MMP24 mRNACTDPMID:28960355
Mmp24Rat1,3,5-trinitro-1,3,5-triazinane decreases expressionEXP 6480464cyclonite results in decreased expression of MMP24 mRNACTDPMID:25559034
Mmp24Rat2,2',4,4'-Tetrabromodiphenyl ether increases expressionEXP 64804642 more ...CTDPMID:27291303
Mmp24Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOMmp24 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of MMP24 mRNACTDPMID:21570461
Mmp24Rat2,4-dinitrotoluene affects expressionEXP 64804642 and 4-dinitrotoluene affects the expression of MMP24 mRNACTDPMID:21346803
Mmp24Rat4,4'-sulfonyldiphenol multiple interactionsEXP 6480464[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of MMP24 mRNACTDPMID:36041667
Mmp24Ratamphetamine increases expressionEXP 6480464Amphetamine results in increased expression of MMP24 mRNACTDPMID:30779732
Mmp24Ratbenzene increases expressionISOMMP24 (Homo sapiens)6480464Benzene results in increased expression of MMP24 mRNACTDPMID:19162166
Mmp24Ratbenzo[a]pyrene affects methylationISOMMP24 (Homo sapiens)6480464Benzo(a)pyrene affects the methylation of MMP24 polyA tailCTDPMID:30157460
Mmp24Ratbisphenol A decreases expressionEXP 6480464bisphenol A results in decreased expression of MMP24 mRNACTDPMID:25181051 and PMID:36779543
Mmp24Ratbisphenol A multiple interactionsEXP 6480464[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of MMP24 mRNACTDPMID:36041667
Mmp24Ratbisphenol F decreases expressionISOMmp24 (Mus musculus)6480464bisphenol F results in decreased expression of MMP24 mRNACTDPMID:38685157
Mmp24Ratbisphenol F multiple interactionsEXP 6480464[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of MMP24 mRNACTDPMID:36041667
Mmp24RatC60 fullerene decreases expressionEXP 6480464fullerene C60 results in decreased expression of MMP24 mRNACTDPMID:19167457
Mmp24Ratcadmium dichloride increases expressionEXP 6480464Cadmium Chloride results in increased expression of MMP24 mRNACTDPMID:33453195
Mmp24Ratcadmium dichloride increases expressionISOMMP24 (Homo sapiens)6480464Cadmium Chloride results in increased expression of MMP24 mRNACTDPMID:38382870
Mmp24Ratcholine multiple interactionsISOMmp24 (Mus musculus)6480464[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of MMP24 mRNACTDPMID:20938992
Mmp24Ratcisplatin decreases expressionISOMMP24 (Homo sapiens)6480464Cisplatin results in decreased expression of MMP24 mRNACTDPMID:27392435 and PMID:27594783
Mmp24Ratcisplatin multiple interactionsISOMMP24 (Homo sapiens)6480464[Cisplatin co-treated with jinfukang] results in decreased expression of MMP24 mRNACTDPMID:27392435

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Biological Process
1 to 20 of 23 rows

  
Object Symbol
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Term
Qualifier
Evidence
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Reference
Notes
Source
Original Reference(s)
Mmp24Ratcell adhesion involved_inIEAUniProtKB-KW:KW-01301600115GO_REF:0000043UniProtGO_REF:0000043
Mmp24Ratcell-cell adhesion mediated by cadherin involved_inIEAUniProtKB:Q9R0S2 and ensembl:ENSMUSP000000291411600115GO_REF:0000107EnsemblGO_REF:0000107
Mmp24Ratcell-cell adhesion mediated by cadherin involved_inISOMmp24 (Mus musculus)1624291 PMID:24952463RGDPMID:24952463
Mmp24Ratcell-cell adhesion mediated by cadherin involved_inISSUniProtKB:Q9R0S21600115GO_REF:0000024UniProtGO_REF:0000024
Mmp24Ratcell-cell adhesion via plasma-membrane adhesion molecules involved_inISSUniProtKB:Q9R0S21600115GO_REF:0000024UniProtGO_REF:0000024
Mmp24Ratcell-cell adhesion via plasma-membrane adhesion molecules involved_inISOMmp24 (Mus musculus)1624291 PMID:19805319RGDPMID:19805319
Mmp24Ratcell-cell adhesion via plasma-membrane adhesion molecules involved_inIEAUniProtKB:Q9R0S2 and ensembl:ENSMUSP000000291411600115GO_REF:0000107EnsemblGO_REF:0000107
Mmp24Ratcollagen catabolic process involved_inIBAMGI:101900 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Mmp24Ratdetection of temperature stimulus involved in sensory perception of pain involved_inISSUniProtKB:Q9R0S21600115GO_REF:0000024UniProtGO_REF:0000024
Mmp24Ratdetection of temperature stimulus involved in sensory perception of pain involved_inISOMmp24 (Mus musculus)1624291 PMID:19805319RGDPMID:19805319
Mmp24Ratdetection of temperature stimulus involved in sensory perception of pain involved_inIEAUniProtKB:Q9R0S2 and ensembl:ENSMUSP000000291411600115GO_REF:0000107EnsemblGO_REF:0000107
Mmp24Ratextracellular matrix organization involved_inIBAFB:FBgn0033438 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Mmp24Ratglial cell differentiation involved_inIEAUniProtKB:Q9R0S2 and ensembl:ENSMUSP000000291411600115GO_REF:0000107EnsemblGO_REF:0000107
Mmp24Ratglial cell differentiation involved_inISOMmp24 (Mus musculus)1624291 PMID:24952463RGDPMID:24952463
Mmp24Ratglial cell differentiation involved_inISSUniProtKB:Q9R0S21600115GO_REF:0000024UniProtGO_REF:0000024
Mmp24Ratneuronal stem cell population maintenance involved_inIEAUniProtKB:Q9R0S2 and ensembl:ENSMUSP000000291411600115GO_REF:0000107EnsemblGO_REF:0000107
Mmp24Ratneuronal stem cell population maintenance involved_inISOMmp24 (Mus musculus)1624291 PMID:24952463RGDPMID:24952463
Mmp24Ratneuronal stem cell population maintenance involved_inISSUniProtKB:Q9R0S21600115GO_REF:0000024UniProtGO_REF:0000024
Mmp24Ratproteolysis involved_inIEAUniProtKB:Q9R0S2 and ensembl:ENSMUSP000000291411600115GO_REF:0000107EnsemblGO_REF:0000107
Mmp24Ratproteolysis involved_inIEAInterPro:IPR001818 more ...1600115GO_REF:0000002InterProGO_REF:0000002
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Cellular Component
1 to 16 of 16 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mmp24Ratextracellular matrix located_inIEAInterPro:IPR0018181600115GO_REF:0000002InterProGO_REF:0000002
Mmp24Ratextracellular region located_inIEAUniProtKB-KW:KW-09641600115GO_REF:0000043UniProtGO_REF:0000043
Mmp24Ratextracellular space is_active_inIBAPANTHER:PTN002565758 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Mmp24RatGolgi apparatus located_inIEAUniProtKB-SubCell:SL-01321600115GO_REF:0000044UniProtGO_REF:0000044
Mmp24RatGolgi apparatus located_inIEAUniProtKB-KW:KW-03331600115GO_REF:0000043UniProtGO_REF:0000043
Mmp24Ratmembrane located_inIEAUniProtKB-SubCell:SL-01621600115GO_REF:0000044UniProtGO_REF:0000044
Mmp24Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Mmp24Ratplasma membrane located_inIEAUniProtKB:Q9R0S2 and ensembl:ENSMUSP000000291411600115GO_REF:0000107EnsemblGO_REF:0000107
Mmp24Ratplasma membrane located_inIEAUniProtKB-KW:KW-10031600115GO_REF:0000043UniProtGO_REF:0000043
Mmp24Ratplasma membrane located_inIEAUniProtKB-SubCell:SL-00391600115GO_REF:0000044UniProtGO_REF:0000044
Mmp24Ratplasma membrane located_inISOMmp24 (Mus musculus)1624291 PMID:14990567RGDPMID:14990567
Mmp24Ratplasma membrane is_active_inIBAMGI:1341867 and PANTHER:PTN0083027881600115GO_REF:0000033GO_CentralGO_REF:0000033
Mmp24Ratplasma membrane located_inISSUniProtKB:Q9R0S21600115GO_REF:0000024UniProtGO_REF:0000024
Mmp24Rattrans-Golgi network membrane located_inIEAUniProtKB:Q9R0S2 and ensembl:ENSMUSP000000291411600115GO_REF:0000107EnsemblGO_REF:0000107
Mmp24Rattrans-Golgi network membrane located_inISOMmp24 (Mus musculus)1624291 PMID:14990567RGDPMID:14990567
Mmp24Rattrans-Golgi network membrane located_inISSUniProtKB:Q9R0S21600115GO_REF:0000024UniProtGO_REF:0000024
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Molecular Function
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Object Symbol
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Term
Qualifier
Evidence
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Reference
Notes
Source
Original Reference(s)
Mmp24Ratcadherin binding enablesIEAUniProtKB:Q9R0S2 and ensembl:ENSMUSP000000291411600115GO_REF:0000107EnsemblGO_REF:0000107
Mmp24Ratcadherin binding enablesISOMmp24 (Mus musculus)1624291UniProtKB:P15116 and PMID:24952463RGDPMID:24952463
Mmp24Rathydrolase activity enablesIEAUniProtKB-KW:KW-03781600115GO_REF:0000043UniProtGO_REF:0000043
Mmp24Ratmetal ion binding enablesIEAUniProtKB-KW:KW-04791600115GO_REF:0000043UniProtGO_REF:0000043
Mmp24Ratmetalloendopeptidase activity enablesISSUniProtKB:Q9R0S21600115GO_REF:0000024UniProtGO_REF:0000024
Mmp24Ratmetalloendopeptidase activity enablesIEAInterPro:IPR001818 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Mmp24Ratmetalloendopeptidase activity enablesIEAUniProtKB:Q9R0S2 and ensembl:ENSMUSP000000291411600115GO_REF:0000107EnsemblGO_REF:0000107
Mmp24Ratmetalloendopeptidase activity enablesIBAFB:FBgn0033438 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Mmp24Ratmetalloendopeptidase activity enablesISOMmp24 (Mus musculus)1624291 PMID:24952463RGDPMID:24952463
Mmp24Ratmetallopeptidase activity enablesIEAInterPro:IPR006026 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Mmp24Ratmetallopeptidase activity enablesIEAUniProtKB-KW:KW-04821600115GO_REF:0000043UniProtGO_REF:0000043
Mmp24Ratpeptidase activity enablesIEAUniProtKB-KW:KW-06451600115GO_REF:0000043UniProtGO_REF:0000043
Mmp24Ratpeptidase activity  TAS 1304227 RGD 
Mmp24Ratzinc ion binding enablesIEAInterPro:IPR001818 more ...1600115GO_REF:0000002InterProGO_REF:0000002
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#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Matrix metalloproteinase (MMP) system in brain: identification and characterization of brain-specific MMP highly expressed in cerebellum. Sekine-Aizawa Y, etal., Eur J Neurosci 2001 Mar;13(5):935-48.
PMID:14990567   PMID:16495457   PMID:19056867   PMID:19805319   PMID:22489706   PMID:24952463  



Mmp24
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83164,739,226 - 164,783,696 (+)NCBIGRCr8
mRatBN7.23144,279,096 - 144,323,572 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3144,279,096 - 144,323,572 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3148,145,188 - 148,188,968 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03156,762,468 - 156,806,235 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03154,501,979 - 154,545,755 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03151,307,309 - 151,355,401 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3151,310,598 - 151,355,401 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03157,676,152 - 157,720,612 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera3143,019,816 - 143,047,813 (+)NCBICelera
Cytogenetic Map3q42NCBI
MMP24
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382035,226,690 - 35,276,998 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2035,226,690 - 35,276,998 (+)EnsemblGRCh38hg38GRCh38
GRCh372033,814,493 - 33,864,801 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362033,278,106 - 33,328,218 (+)NCBINCBI36Build 36hg18NCBI36
Build 342033,278,107 - 33,326,511NCBI
Celera2030,583,249 - 30,613,409 (+)NCBICelera
Cytogenetic Map20q11.22NCBI
HuRef2030,592,010 - 30,642,227 (+)NCBIHuRef
CHM1_12033,715,680 - 33,765,882 (+)NCBICHM1_1
T2T-CHM13v2.02036,947,464 - 36,997,860 (+)NCBIT2T-CHM13v2.0
Mmp24
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392155,617,262 - 155,660,286 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2155,617,262 - 155,660,286 (+)EnsemblGRCm39 Ensembl
GRCm382155,775,342 - 155,818,367 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2155,775,342 - 155,818,366 (+)EnsemblGRCm38mm10GRCm38
MGSCv372155,601,080 - 155,644,102 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362155,466,840 - 155,509,807 (+)NCBIMGSCv36mm8
Celera2161,724,940 - 161,750,893 (+)NCBICelera
Cytogenetic Map2H1NCBI
cM Map277.26NCBI
Mmp24
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542226,126,929 - 26,154,285 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542226,128,403 - 26,154,285 (-)NCBIChiLan1.0ChiLan1.0
MMP24
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22140,959,852 - 41,010,276 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12040,952,956 - 41,004,532 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02031,554,770 - 31,606,348 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12032,686,887 - 32,729,403 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2032,686,887 - 32,729,403 (+)Ensemblpanpan1.1panPan2
MMP24
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12424,223,049 - 24,258,082 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2424,232,833 - 24,255,725 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2423,861,305 - 23,903,980 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02424,907,564 - 24,950,248 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2424,907,564 - 24,949,757 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12424,194,434 - 24,237,113 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02424,276,885 - 24,332,128 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02424,728,551 - 24,771,226 (+)NCBIUU_Cfam_GSD_1.0
Mmp24
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640173,248,000 - 173,270,439 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365615,478,145 - 5,502,529 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365615,479,107 - 5,501,559 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MMP24
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1738,588,081 - 38,636,627 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11738,587,230 - 38,636,628 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
MMP24
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1256,153,277 - 56,183,026 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl256,152,944 - 56,184,605 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660872,304,079 - 2,334,298 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mmp24
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248424,131,523 - 4,160,134 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248424,133,323 - 4,159,501 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Mmp24
472 total Variants

Predicted Target Of
Summary Value
Count of predictions:323
Count of miRNA genes:170
Interacting mature miRNAs:229
Transcripts:ENSRNOT00000073642
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 33 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
1598877Bp285Blood pressure QTL 2851.50.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3120538241165538241Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3130656562169034231Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
1298068Bp167Blood pressure QTL 1670.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3141074471169034231Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
2298477Eau4Experimental allergic uveoretinitis QTL 40.0011uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)3137398739169034231Rat
61335Bp20Blood pressure QTL 203arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3141339236155617360Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat

1 to 10 of 33 rows
D3Got110  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23144,294,166 - 144,294,324 (+)MAPPERmRatBN7.2
Rnor_6.03151,325,473 - 151,325,630NCBIRnor6.0
Rnor_5.03157,691,028 - 157,691,185UniSTSRnor5.0
RGSC_v3.43146,313,319 - 146,313,477RGDRGSC3.4
RGSC_v3.43146,313,320 - 146,313,477UniSTSRGSC3.4
RGSC_v3.13146,218,942 - 146,219,099RGD
Celera3143,018,692 - 143,018,849UniSTS
RH 3.4 Map31317.3UniSTS
RH 3.4 Map31317.3RGD
RH 2.0 Map3888.2RGD
RH128047  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24141,096,667 - 141,096,848 (+)MAPPERmRatBN7.2
mRatBN7.23144,323,037 - 144,323,218 (+)MAPPERmRatBN7.2
Rnor_6.03151,354,867 - 151,355,047NCBIRnor6.0
Rnor_6.04140,156,713 - 140,156,893NCBIRnor6.0
Rnor_5.04204,624,591 - 204,624,771UniSTSRnor5.0
Rnor_5.03157,720,078 - 157,720,258UniSTSRnor5.0
RGSC_v3.44143,614,485 - 143,614,665UniSTSRGSC3.4
Celera4129,748,880 - 129,749,060UniSTS
Celera3143,047,279 - 143,047,459UniSTS
RH 3.4 Map4875.22UniSTS
Cytogenetic Map4q41UniSTS
RH135119  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23144,323,641 - 144,323,849 (+)MAPPERmRatBN7.2
Rnor_6.03151,355,471 - 151,355,678NCBIRnor6.0
Rnor_5.03157,720,682 - 157,720,889UniSTSRnor5.0
Celera3143,047,883 - 143,048,090UniSTS
RH 3.4 Map31308.1UniSTS
RH135475  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23144,319,172 - 144,319,347 (+)MAPPERmRatBN7.2
Rnor_6.03151,351,002 - 151,351,176NCBIRnor6.0
Rnor_5.03157,716,213 - 157,716,387UniSTSRnor5.0
Celera3143,043,415 - 143,043,589UniSTS
REN57077  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23144,321,665 - 144,321,910 (+)MAPPERmRatBN7.2
Rnor_6.03151,353,495 - 151,353,739NCBIRnor6.0
Rnor_5.03157,718,706 - 157,718,950UniSTSRnor5.0
Celera3143,045,907 - 143,046,151UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000073642   ⟹   ENSRNOP00000067398
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3144,295,007 - 144,323,572 (+)Ensembl
Rnor_6.0 Ensembl3151,335,292 - 151,355,401 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000092194   ⟹   ENSRNOP00000075211
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3144,279,096 - 144,323,572 (+)Ensembl
Rnor_6.0 Ensembl3151,310,598 - 151,353,117 (+)Ensembl
RefSeq Acc Id: NM_031757   ⟹   NP_113945
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83164,739,226 - 164,783,696 (+)NCBI
mRatBN7.23144,279,096 - 144,323,572 (+)NCBI
Rnor_6.03151,307,309 - 151,355,401 (+)NCBI
Rnor_5.03157,676,152 - 157,720,612 (+)NCBI
Celera3143,019,816 - 143,047,813 (+)RGD
Sequence:
Protein RefSeqs NP_113945 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAB32589 (Get FASTA)   NCBI Sequence Viewer  
  EDL85896 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000075211
  ENSRNOP00000075211.2
GenBank Protein Q99PW6 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_113945   ⟸   NM_031757
- Peptide Label: precursor
- UniProtKB: Q99PW6 (UniProtKB/Swiss-Prot),   A0A0G2KA10 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000075211   ⟸   ENSRNOT00000092194
Ensembl Acc Id: ENSRNOP00000067398   ⟸   ENSRNOT00000073642
Peptidase metallopeptidase

Name Modeler Protein Id AA Range Protein Structure
AF-Q99PW6-F1-model_v2 AlphaFold Q99PW6 1-618 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 40 of 42 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-47118 BioCyc
Ensembl Genes ENSRNOG00000047028 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000092194 ENTREZGENE
  ENSRNOT00000092194.2 UniProtKB/Swiss-Prot
Gene3D-CATH 2.110.10.10 UniProtKB/Swiss-Prot
  3.40.390.10 UniProtKB/Swiss-Prot
InterPro Hemopexin-like_dom UniProtKB/Swiss-Prot
  Hemopexin-like_dom_sf UniProtKB/Swiss-Prot
  Hemopexin-like_repeat UniProtKB/Swiss-Prot
  Hemopexin_CS UniProtKB/Swiss-Prot
  M10A_MMP UniProtKB/Swiss-Prot
  MetalloPept_cat_dom_sf UniProtKB/Swiss-Prot
  Pept_M10_metallopeptidase UniProtKB/Swiss-Prot
  Pept_M10A UniProtKB/Swiss-Prot
  Pept_M10A_metallopeptidase_C UniProtKB/Swiss-Prot
  Peptidase_Metallo UniProtKB/Swiss-Prot
  Peptidoglycan-bd-like UniProtKB/Swiss-Prot
  PGBD-like_sf UniProtKB/Swiss-Prot
KEGG Report rno:83513 UniProtKB/Swiss-Prot
NCBI Gene 83513 ENTREZGENE
PANTHER MATRIX METALLOPROTEINASE UniProtKB/Swiss-Prot
  PTHR10201:SF138 UniProtKB/Swiss-Prot
Pfam DUF3377 UniProtKB/Swiss-Prot
  Hemopexin UniProtKB/Swiss-Prot
  Peptidase_M10 UniProtKB/Swiss-Prot
  PG_binding_1 UniProtKB/Swiss-Prot
PhenoGen Mmp24 PhenoGen
PIRSF Peptidase_M10A_matrix UniProtKB/Swiss-Prot
PRINTS MATRIXIN UniProtKB/Swiss-Prot
PROSITE HEMOPEXIN UniProtKB/Swiss-Prot
  HEMOPEXIN_2 UniProtKB/Swiss-Prot
  ZINC_PROTEASE UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000047028 RatGTEx
SMART SM00120 UniProtKB/Swiss-Prot
  ZnMc UniProtKB/Swiss-Prot
Superfamily-SCOP Metalloproteases ('zincins'), catalytic domain UniProtKB/Swiss-Prot
  SSF47090 UniProtKB/Swiss-Prot
  SSF50923 UniProtKB/Swiss-Prot
UniProt A0A0G2KA10 ENTREZGENE, UniProtKB/TrEMBL
  A6KI59_RAT UniProtKB/TrEMBL
1 to 40 of 42 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-01-20 Mmp24  matrix metallopeptidase 24    matrix metalloproteinase 24 (membrane-inserted)  Name updated 1299863 APPROVED
2002-08-07 Mmp24  matrix metalloproteinase 24 (membrane-inserted)      Symbol and Name status set to provisional 70820 PROVISIONAL