Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Mmp23 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Mmp23 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of MMP23 mRNA | CTD | PMID:36331819 | Mmp23 | Rat | 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane | increases expression | ISO | Mmp23 (Mus musculus) | 6480464 | o,p'-DDT results in increased expression of MMP23 mRNA | CTD | PMID:24096037 | Mmp23 | Rat | 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane | increases expression | EXP | | 6480464 | o,p'-DDT results in increased expression of MMP23 mRNA | CTD | PMID:24096037 | Mmp23 | Rat | 1,2-dimethylhydrazine | increases expression | ISO | Mmp23 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in increased expression of MMP23 mRNA | CTD | PMID:22206623 | Mmp23 | Rat | 17alpha-ethynylestradiol | increases expression | ISO | Mmp23 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of MMP23 mRNA | CTD | PMID:17942748 | Mmp23 | Rat | 17alpha-ethynylestradiol | multiple interactions | ISO | Mmp23 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MMP23 mRNA | CTD | PMID:17942748 | Mmp23 | Rat | 17beta-estradiol | increases expression | EXP | | 6480464 | Estradiol results in increased expression of MMP23 mRNA | CTD | PMID:32145629 | Mmp23 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Mmp23 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MMP23 mRNA | CTD | PMID:17942748 | Mmp23 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of MMP23 mRNA | CTD | PMID:34747641 | Mmp23 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Mmp23 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of MMP23 mRNA | CTD | PMID:15328365|PMID:23994337 | Mmp23 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Mmp23 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of MMP23 mRNA | CTD | PMID:21570461 | Mmp23 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of MMP23 mRNA | CTD | PMID:16960034 | Mmp23 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Mmp23 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of MMP23 mRNA | CTD | PMID:16960034 | Mmp23 | Rat | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | affects expression | ISO | Mmp23 (Mus musculus) | 6480464 | 2,2',4,4',5-brominated diphenyl ether affects the expression of MMP23 mRNA | CTD | PMID:38648751 | Mmp23 | Rat | 3,3',4,4',5-pentachlorobiphenyl | decreases expression | ISO | Mmp23 (Mus musculus) | 6480464 | 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MMP23 mRNA | CTD | PMID:23994337 | Mmp23 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | MMP23B (Homo sapiens) | 6480464 | bisphenol S results in increased expression of MMP23B mRNA | CTD | PMID:25912373 | Mmp23 | Rat | 4,4'-sulfonyldiphenol | affects methylation | ISO | Mmp23 (Mus musculus) | 6480464 | bisphenol S affects the methylation of MMP23 gene | CTD | PMID:31683443 | Mmp23 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | Mmp23 (Mus musculus) | 6480464 | bisphenol S results in increased expression of MMP23 mRNA | CTD | PMID:30951980 | Mmp23 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of MMP23 mRNA | CTD | PMID:24780913 | Mmp23 | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of MMP23 mRNA | CTD | PMID:30047161 | Mmp23 | Rat | all-trans-retinoic acid | multiple interactions | ISO | Mmp23 (Mus musculus) | 6480464 | [bisphenol A co-treated with Tretinoin] results in decreased expression of MMP23 mRNA; [bisphenol F co-treated more ... | CTD | PMID:30951980 | Mmp23 | Rat | alpha-Zearalanol | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of MMP23 mRNA | CTD | PMID:35163327 | Mmp23 | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of MMP23 mRNA | CTD | PMID:16483693 | Mmp23 | Rat | Azoxymethane | multiple interactions | ISO | Mmp23 (Mus musculus) | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of MMP23 more ... | CTD | PMID:29950665 | Mmp23 | Rat | benzo[a]pyrene | increases expression | ISO | Mmp23 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of MMP23 mRNA | CTD | PMID:22228805 | Mmp23 | Rat | benzo[a]pyrene | decreases methylation | ISO | MMP23B (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of MMP23B promoter | CTD | PMID:27901495 | Mmp23 | Rat | benzo[a]pyrene | increases expression | ISO | MMP23B (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of MMP23B mRNA | CTD | PMID:22316170 | Mmp23 | Rat | benzo[b]fluoranthene | decreases expression | ISO | Mmp23 (Mus musculus) | 6480464 | benzo(b)fluoranthene results in decreased expression of MMP23 mRNA | CTD | PMID:26377693 | Mmp23 | Rat | beta-naphthoflavone | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MMP23 mRNA | CTD | PMID:18164116 | Mmp23 | Rat | beta-naphthoflavone | decreases expression | ISO | Mmp23 (Mus musculus) | 6480464 | beta-Naphthoflavone results in decreased expression of MMP23 mRNA | CTD | PMID:23994337 | Mmp23 | Rat | bis(2-ethylhexyl) phthalate | increases expression | ISO | Mmp23 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in increased expression of MMP23 mRNA | CTD | PMID:33754040 | Mmp23 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of MMP23B mRNA | CTD | PMID:25181051 | Mmp23 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of MMP23 mRNA | CTD | PMID:32145629 | Mmp23 | Rat | bisphenol A | multiple interactions | ISO | Mmp23 (Mus musculus) | 6480464 | [bisphenol A co-treated with Tretinoin] results in decreased expression of MMP23 mRNA | CTD | PMID:30951980 | Mmp23 | Rat | bisphenol A | increases expression | ISO | Mmp23 (Mus musculus) | 6480464 | bisphenol A results in increased expression of MMP23 mRNA | CTD | PMID:30951980 | Mmp23 | Rat | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of MMP23 gene | CTD | PMID:28505145 | Mmp23 | Rat | bisphenol AF | increases expression | ISO | MMP23B (Homo sapiens) | 6480464 | bisphenol AF results in increased expression of MMP23B mRNA | CTD | PMID:25912373 | Mmp23 | Rat | bisphenol F | increases expression | ISO | Mmp23 (Mus musculus) | 6480464 | bisphenol F results in increased expression of MMP23 mRNA | CTD | PMID:30951980 | Mmp23 | Rat | bisphenol F | decreases expression | ISO | Mmp23 (Mus musculus) | 6480464 | bisphenol F results in decreased expression of MMP23 mRNA | CTD | PMID:38685157 | Mmp23 | Rat | bisphenol F | multiple interactions | ISO | Mmp23 (Mus musculus) | 6480464 | [bisphenol F co-treated with Tretinoin] results in decreased expression of MMP23 mRNA | CTD | PMID:30951980 | Mmp23 | Rat | bleomycin A2 | increases expression | ISO | Mmp23 (Mus musculus) | 6480464 | Bleomycin results in increased expression of MMP23 mRNA | CTD | PMID:36087614 | Mmp23 | Rat | Butylbenzyl phthalate | increases expression | EXP | | 6480464 | butylbenzyl phthalate results in increased expression of MMP23 mRNA | CTD | PMID:21241498 | Mmp23 | Rat | cannabidiol | increases expression | ISO | Mmp23 (Mus musculus) | 6480464 | Cannabidiol results in increased expression of MMP23 mRNA | CTD | PMID:21542829|PMID:22178458 | Mmp23 | Rat | choline | multiple interactions | ISO | Mmp23 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression more ... | CTD | PMID:20938992 | Mmp23 | Rat | cocaine | affects expression | EXP | | 6480464 | Cocaine affects the expression of MMP23 mRNA | CTD | PMID:20187946 | Mmp23 | Rat | cocaine | increases expression | EXP | | 6480464 | Cocaine results in increased expression of MMP23 mRNA | CTD | PMID:17898221 | Mmp23 | Rat | cytarabine | decreases expression | ISO | MMP23B (Homo sapiens) | 6480464 | Cytarabine results in decreased expression of MMP23B mRNA | CTD | PMID:21198554 | Mmp23 | Rat | dextran sulfate | multiple interactions | ISO | Mmp23 (Mus musculus) | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of MMP23 more ... | CTD | PMID:29950665 | Mmp23 | Rat | Dibutyl phosphate | affects expression | ISO | MMP23B (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of MMP23B mRNA | CTD | PMID:37042841 | Mmp23 | Rat | dibutyl phthalate | increases expression | ISO | Mmp23 (Mus musculus) | 6480464 | Dibutyl Phthalate results in increased expression of MMP23 mRNA | CTD | PMID:21266533 | Mmp23 | Rat | diethylstilbestrol | increases expression | EXP | | 6480464 | Diethylstilbestrol results in increased expression of MMP23 mRNA | CTD | PMID:21658437 | Mmp23 | Rat | dimethylarsinic acid | increases methylation | EXP | | 6480464 | Cacodylic Acid results in increased methylation of MMP23 gene | CTD | PMID:37958445 | Mmp23 | Rat | doxorubicin | decreases expression | ISO | MMP23B (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of MMP23B mRNA | CTD | PMID:29803840 | Mmp23 | Rat | ethanol | decreases expression | EXP | | 6480464 | Ethanol results in decreased expression of MMP23 mRNA | CTD | PMID:17920746 | Mmp23 | Rat | ferric oxide | multiple interactions | ISO | Mmp23 (Mus musculus) | 6480464 | [Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of MMP23 mRNA | CTD | PMID:20540983 | Mmp23 | Rat | folic acid | multiple interactions | ISO | Mmp23 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression more ... | CTD | PMID:20938992 | Mmp23 | Rat | furan | increases methylation | EXP | | 6480464 | furan results in increased methylation of MMP23 gene | CTD | PMID:22079235 | Mmp23 | Rat | furan | increases expression | EXP | | 6480464 | furan results in increased expression of MMP23 mRNA | CTD | PMID:27387713 | Mmp23 | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of MMP23 mRNA | CTD | PMID:22061828 | Mmp23 | Rat | isotretinoin | increases expression | ISO | MMP23B (Homo sapiens) | 6480464 | Isotretinoin results in increased expression of MMP23B mRNA | CTD | PMID:20436886 | Mmp23 | Rat | ivermectin | decreases expression | ISO | MMP23B (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of MMP23B protein | CTD | PMID:32959892 | Mmp23 | Rat | L-methionine | multiple interactions | ISO | Mmp23 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression more ... | CTD | PMID:20938992 | Mmp23 | Rat | losartan | decreases expression | EXP | | 6480464 | Losartan results in decreased expression of MMP23 mRNA | CTD | PMID:15100363 | Mmp23 | Rat | methimazole | increases expression | EXP | | 6480464 | Methimazole results in increased expression of MMP23 mRNA | CTD | PMID:30047161 | Mmp23 | Rat | mono(2-ethylhexyl) phthalate | decreases expression | ISO | MMP23B (Homo sapiens) | 6480464 | mono-(2-ethylhexyl)phthalate results in decreased expression of MMP23B mRNA | CTD | PMID:36695872 | Mmp23 | Rat | N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal | multiple interactions | ISO | Mmp23 (Mus musculus) | 6480464 | [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of MMP23 more ... | CTD | PMID:25566086 | Mmp23 | Rat | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MMP23 mRNA | CTD | PMID:18164116 | Mmp23 | Rat | naphthalene | increases expression | ISO | Mmp23 (Mus musculus) | 6480464 | naphthalene results in increased expression of MMP23 mRNA | CTD | PMID:18978301 | Mmp23 | Rat | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in increased expression of MMP23 mRNA | CTD | PMID:25729387 | Mmp23 | Rat | oxaliplatin | increases expression | EXP | | 6480464 | oxaliplatin results in increased expression of MMP23 mRNA | CTD | PMID:25729387 | Mmp23 | Rat | paracetamol | affects expression | ISO | Mmp23 (Mus musculus) | 6480464 | Acetaminophen affects the expression of MMP23 mRNA | CTD | PMID:17562736 | Mmp23 | Rat | paracetamol | increases expression | ISO | Mmp23 (Mus musculus) | 6480464 | Acetaminophen results in increased expression of MMP23 mRNA | CTD | PMID:34724096 | Mmp23 | Rat | perfluorohexanesulfonic acid | increases expression | ISO | Mmp23 (Mus musculus) | 6480464 | perfluorohexanesulfonic acid results in increased expression of MMP23 mRNA | CTD | PMID:37995155 | Mmp23 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Mmp23 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of MMP23 mRNA | CTD | PMID:36331819 | Mmp23 | Rat | perfluorooctanoic acid | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of MMP23 mRNA | CTD | PMID:35163327 | Mmp23 | Rat | pyrogallol | increases expression | ISO | Mmp23 (Mus musculus) | 6480464 | Pyrogallol results in increased expression of MMP23 mRNA | CTD | PMID:20362636 | Mmp23 | Rat | resveratrol | multiple interactions | ISO | MMP23B (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of MMP23B mRNA | CTD | PMID:23557933 | Mmp23 | Rat | rotenone | increases expression | ISO | MMP23B (Homo sapiens) | 6480464 | Rotenone results in increased expression of MMP23B mRNA | CTD | PMID:29955902 | Mmp23 | Rat | sunitinib | decreases expression | ISO | MMP23B (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of MMP23B mRNA | CTD | PMID:31533062 | Mmp23 | Rat | tetrachloromethane | affects expression | ISO | Mmp23 (Mus musculus) | 6480464 | Carbon Tetrachloride affects the expression of MMP23 mRNA | CTD | PMID:17484886 | Mmp23 | Rat | titanium dioxide | decreases expression | ISO | Mmp23 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of MMP23 mRNA | CTD | PMID:23557971 | Mmp23 | Rat | titanium dioxide | affects methylation | ISO | Mmp23 (Mus musculus) | 6480464 | titanium dioxide affects the methylation of MMP23 gene | CTD | PMID:35295148 | Mmp23 | Rat | titanium dioxide | multiple interactions | ISO | Mmp23 (Mus musculus) | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of MMP23 more ... | CTD | PMID:29950665 | Mmp23 | Rat | topotecan | increases expression | EXP | | 6480464 | Topotecan results in increased expression of MMP23 mRNA | CTD | PMID:25729387 | Mmp23 | Rat | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in increased expression of MMP23 mRNA | CTD | PMID:25729387 | Mmp23 | Rat | valproic acid | increases methylation | ISO | MMP23B (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of MMP23B gene | CTD | PMID:29154799 | Mmp23 | Rat | zoledronic acid | increases expression | ISO | MMP23B (Homo sapiens) | 6480464 | zoledronic acid results in increased expression of MMP23B mRNA | CTD | PMID:24714768 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||





















