Phkb (phosphorylase kinase regulatory subunit beta) - Rat Genome Database

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Gene: Phkb (phosphorylase kinase regulatory subunit beta) Rattus norvegicus
Analyze
Symbol: Phkb
Name: phosphorylase kinase regulatory subunit beta
RGD ID: 620186
Description: Predicted to enable calmodulin binding activity. Involved in protein phosphorylation. Part of phosphorylase kinase complex. Human ortholog(s) of this gene implicated in glycogen storage disease IXb. Orthologous to human PHKB (phosphorylase kinase regulatory subunit beta); PARTICIPATES IN glycogen degradation pathway; calcium/calcium-mediated signaling pathway; insulin signaling pathway; INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC361377; phosphorylase b kinase regulatory subunit beta; phosphorylase kinase beta subunit; phosphorylase kinase, beta; similar to phosphorylase kinase (EC 2.7.1.38) beta chain, non-muscle - rabbit
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81937,179,937 - 37,383,979 (-)NCBIGRCr8
mRatBN7.21921,013,719 - 21,210,671 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1921,025,733 - 21,210,633 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1922,713,124 - 22,893,420 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01927,907,652 - 28,087,942 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01930,870,462 - 31,050,747 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01922,031,684 - 22,281,788 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1922,033,228 - 22,281,778 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01933,031,043 - 33,289,256 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41922,373,355 - 22,561,509 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11922,378,643 - 22,380,741 (-)NCBI
Celera1920,893,425 - 21,075,361 (-)NCBICelera
Cytogenetic Map19p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
alpha-Zearalanol  (EXP)
amitrole  (EXP)
antimycin A  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
bisphenol A  (EXP)
bisphenol F  (ISO)
bortezomib  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
CGP 52608  (ISO)
cisplatin  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
dextran sulfate  (ISO)
dioxygen  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
formaldehyde  (ISO)
gentamycin  (EXP)
inulin  (ISO)
ivermectin  (ISO)
lead diacetate  (EXP)
lead(0)  (ISO)
methimazole  (EXP)
methotrexate  (ISO)
methylmercury chloride  (ISO)
monosodium L-glutamate  (ISO)
N-Acetyl-S-(1,2-dichlorovinyl)-cysteine  (ISO)
nickel atom  (ISO)
ozone  (EXP,ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (ISO)
picoxystrobin  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
quercetin  (ISO)
rotenone  (ISO)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
tebufenpyrad  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP,ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
trovafloxacin  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phosphorylase kinase: the complexity of its regulation is reflected in the complexity of its structure. Brushia RJ and Walsh DA, Front Biosci. 1999 Sep 15;4:D618-41.
2. Coordinated expression of phosphorylase kinase subunits in regenerating skeletal muscle. Cawley KC, etal., J Biol Chem 1992 Aug 25;267(24):17287-95.
3. Purification of rat liver phosphorylase kinase. Chrisman TD, etal., J Biol Chem. 1982 Sep 25;257(18):10798-804.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. The alpha and beta subunits of phosphorylase kinase are homologous: cDNA cloning and primary structure of the beta subunit. Kilimann MW, etal., Proc Natl Acad Sci U S A 1988 Dec;85(24):9381-5.
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. GOA pipeline RGD automated data pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Rat skeletal muscle phosphorylase kinase: turnover and control of isozyme levels in culture. Salsgiver WJ and Lawrence JC Jr, Am J Physiol. 1986 Mar;250(3 Pt 1):C365-73.
Additional References at PubMed
PMID:12477932  


Genomics

Comparative Map Data
Phkb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81937,179,937 - 37,383,979 (-)NCBIGRCr8
mRatBN7.21921,013,719 - 21,210,671 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1921,025,733 - 21,210,633 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1922,713,124 - 22,893,420 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01927,907,652 - 28,087,942 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01930,870,462 - 31,050,747 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01922,031,684 - 22,281,788 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1922,033,228 - 22,281,778 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01933,031,043 - 33,289,256 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41922,373,355 - 22,561,509 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11922,378,643 - 22,380,741 (-)NCBI
Celera1920,893,425 - 21,075,361 (-)NCBICelera
Cytogenetic Map19p11NCBI
PHKB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381647,461,299 - 47,701,523 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1647,461,123 - 47,701,523 (+)EnsemblGRCh38hg38GRCh38
GRCh371647,495,210 - 47,735,434 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361646,052,739 - 46,291,755 (+)NCBINCBI36Build 36hg18NCBI36
Build 341646,052,738 - 46,291,755NCBI
Celera1632,003,151 - 32,243,373 (+)NCBICelera
Cytogenetic Map16q12.1NCBI
HuRef1633,385,772 - 33,625,996 (+)NCBIHuRef
CHM1_11648,902,240 - 49,142,934 (+)NCBICHM1_1
T2T-CHM13v2.01653,258,117 - 53,498,326 (+)NCBIT2T-CHM13v2.0
Phkb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39886,567,489 - 86,790,883 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl886,567,588 - 86,788,005 (+)EnsemblGRCm39 Ensembl
GRCm38885,840,853 - 86,064,251 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl885,840,959 - 86,061,376 (+)EnsemblGRCm38mm10GRCm38
MGSCv37888,364,901 - 88,584,541 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36888,731,107 - 88,950,747 (+)NCBIMGSCv36mm8
Celera890,138,260 - 90,352,039 (+)NCBICelera
Cytogenetic Map8C3NCBI
cM Map841.61NCBI
Phkb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554747,598,463 - 7,801,083 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554747,599,657 - 7,801,083 (-)NCBIChiLan1.0ChiLan1.0
PHKB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21856,914,379 - 57,154,821 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11662,819,336 - 63,059,963 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01627,720,300 - 27,960,740 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11646,612,062 - 46,853,157 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1646,612,053 - 46,853,157 (+)Ensemblpanpan1.1panPan2
PHKB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1267,260,532 - 67,476,596 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl267,254,542 - 67,476,532 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha263,836,201 - 64,052,047 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0267,818,656 - 68,034,694 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl267,818,659 - 68,034,650 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1264,631,779 - 64,847,974 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0265,655,460 - 65,871,221 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0266,543,573 - 66,759,826 (-)NCBIUU_Cfam_GSD_1.0
Phkb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934958,586,224 - 58,809,915 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936475779,302 - 1,003,262 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936475779,238 - 1,002,851 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PHKB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl636,991,274 - 37,193,593 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1636,994,424 - 37,193,631 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2632,141,368 - 32,246,744 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PHKB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1533,288,396 - 33,512,445 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl533,291,009 - 33,513,244 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604743,031,736 - 43,259,030 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Phkb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249141,013,145 - 1,234,610 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249141,013,828 - 1,235,023 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Phkb
753 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:132
Count of miRNA genes:105
Interacting mature miRNAs:117
Transcripts:ENSRNOT00000049624
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1549847Bss8Bone structure and strength QTL 84lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)19131963836Rat
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)19231612147316121Rat
631681Cm12Cardiac mass QTL 123.330.00053heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)19128982497Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19136824771Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19409615555283277Rat
2298478Eau8Experimental allergic uveoretinitis QTL 80.0163uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)191715443357337602Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)191563020157337602Rat
1558656Prcs1Prostate cancer susceptibility QTL 15prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)191511459834521833Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19136824771Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)191560502346559041Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19218792756457239Rat
724565Tcas5Tongue tumor susceptibility QTL 510.04tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)19997775339654489Rat
61407Scl12Serum cholesterol level QTL 120.001blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)191392640130303727Rat
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19136824771Rat
61350Bp32Blood pressure QTL 320.012arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192048357557337602Rat
631840Niddm38Non-insulin dependent diabetes mellitus QTL 383.86blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)191032318023069265Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)191545586057337602Rat
10054132Srcrt9Stress Responsive Cort QTL 92.870.0017blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19127355345Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19745724942983518Rat
8694186Bw152Body weight QTL 1523.340.001body mass (VT:0001259)body weight gain (CMO:0000420)1956937445569374Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191082797043544039Rat
7411590Foco7Food consumption QTL 76.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)19124688055Rat
631678Cm9Cardiac mass QTL 94.270.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)19128982497Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19136824771Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)19320477748204777Rat
9589102Slep13Serum leptin concentration QTL 134.630.001blood leptin amount (VT:0005667)plasma leptin level (CMO:0000781)1956937445569374Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19218792746708701Rat

Markers in Region
RH144404  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21921,036,159 - 21,036,375 (+)MAPPERmRatBN7.2
Rnor_6.01922,042,117 - 22,042,332NCBIRnor6.0
Rnor_5.01933,053,642 - 33,053,857UniSTSRnor5.0
RGSC_v3.41922,381,924 - 22,382,139UniSTSRGSC3.4
Celera1920,901,792 - 20,902,007UniSTS
Cytogenetic Map19q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000049624   ⟹   ENSRNOP00000039778
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1921,027,165 - 21,210,605 (-)Ensembl
Rnor_6.0 Ensembl1922,033,730 - 22,281,778 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000086187   ⟹   ENSRNOP00000074948
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1921,027,165 - 21,210,633 (-)Ensembl
Rnor_6.0 Ensembl1922,033,228 - 22,194,740 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000109870   ⟹   ENSRNOP00000076912
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1921,027,165 - 21,175,679 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000110468   ⟹   ENSRNOP00000083595
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1921,025,733 - 21,210,592 (-)Ensembl
RefSeq Acc Id: NM_001014152   ⟹   NP_001014174
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81937,201,005 - 37,383,854 (-)NCBI
mRatBN7.21921,027,764 - 21,210,605 (-)NCBI
Rnor_6.01922,033,722 - 22,281,778 (-)NCBI
Rnor_5.01933,031,043 - 33,289,256 (-)NCBI
RGSC_v3.41922,373,355 - 22,561,509 (-)RGD
Celera1920,893,425 - 21,075,361 (-)RGD
Sequence:
RefSeq Acc Id: NM_001414932   ⟹   NP_001401861
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81937,195,425 - 37,383,877 (-)NCBI
mRatBN7.21921,022,184 - 21,210,628 (-)NCBI
RefSeq Acc Id: NM_001414933   ⟹   NP_001401862
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81937,195,425 - 37,383,877 (-)NCBI
mRatBN7.21921,022,184 - 21,210,628 (-)NCBI
RefSeq Acc Id: NM_001414934   ⟹   NP_001401863
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81937,195,425 - 37,383,877 (-)NCBI
mRatBN7.21921,022,184 - 21,210,628 (-)NCBI
RefSeq Acc Id: XM_063278110   ⟹   XP_063134180
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81937,200,993 - 37,383,885 (-)NCBI
RefSeq Acc Id: XM_063278111   ⟹   XP_063134181
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81937,179,937 - 37,383,973 (-)NCBI
RefSeq Acc Id: XM_063278112   ⟹   XP_063134182
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81937,228,815 - 37,383,978 (-)NCBI
RefSeq Acc Id: XR_010060011
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81937,228,803 - 37,383,979 (-)NCBI
RefSeq Acc Id: NP_001014174   ⟸   NM_001014152
- Peptide Label: isoform 4
- UniProtKB: A0A8I5Y5Q0 (UniProtKB/TrEMBL),   F1LNP9 (UniProtKB/TrEMBL),   Q5RKH5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000039778   ⟸   ENSRNOT00000049624
Ensembl Acc Id: ENSRNOP00000074948   ⟸   ENSRNOT00000086187
Ensembl Acc Id: ENSRNOP00000083595   ⟸   ENSRNOT00000110468
Ensembl Acc Id: ENSRNOP00000076912   ⟸   ENSRNOT00000109870
RefSeq Acc Id: NP_001401862   ⟸   NM_001414933
- Peptide Label: isoform 2
RefSeq Acc Id: NP_001401861   ⟸   NM_001414932
- Peptide Label: isoform 1
- UniProtKB: A0A8J8YFM3 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001401863   ⟸   NM_001414934
- Peptide Label: isoform 3
- UniProtKB: A6KDC6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063134181   ⟸   XM_063278111
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063134180   ⟸   XM_063278110
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063134182   ⟸   XM_063278112
- Peptide Label: isoform X3
Protein Domains
GH15-like   Phosphorylase b kinase regulatory subunit alpha/beta

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5RKH5-F1-model_v2 AlphaFold Q5RKH5 1-1100 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700988
Promoter ID:EPDNEW_R11511
Type:initiation region
Name:Phkb_1
Description:phosphorylase kinase regulatory subunit beta
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01922,281,769 - 22,281,829EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620186 AgrOrtholog
BioCyc Gene G2FUF-6220 BioCyc
Ensembl Genes ENSRNOG00000024101 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000049624.5 UniProtKB/TrEMBL
  ENSRNOT00000086187.2 UniProtKB/TrEMBL
  ENSRNOT00000109870.1 UniProtKB/TrEMBL
  ENSRNOT00000110468.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7096506 IMAGE-MGC_LOAD
InterPro 6-hairpin_glycosidase-like UniProtKB/TrEMBL
  Glyco_hydro_15 UniProtKB/TrEMBL
  KPBA/B_C UniProtKB/TrEMBL
  PHK_AB UniProtKB/TrEMBL
MGC_CLONE MGC:94757 IMAGE-MGC_LOAD
NCBI Gene Phkb ENTREZGENE
PANTHER PHK_AB UniProtKB/TrEMBL
  PHOSPHORYLASE B KINASE REGULATORY SUBUNIT BETA UniProtKB/TrEMBL
Pfam Glyco_hydro_15 UniProtKB/TrEMBL
  KPBB_C UniProtKB/TrEMBL
PhenoGen Phkb PhenoGen
RatGTEx ENSRNOG00000024101 RatGTEx
Superfamily-SCOP Glyco_trans_6hp UniProtKB/TrEMBL
UniProt A0A0G2K9C8_RAT UniProtKB/TrEMBL
  A0A8I5Y5Q0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZXC2_RAT UniProtKB/TrEMBL
  A0A8J8YFM3 ENTREZGENE, UniProtKB/TrEMBL
  A6KDC6 ENTREZGENE, UniProtKB/TrEMBL
  F1LNP9 ENTREZGENE
  Q5RKH5 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary F1LNP9 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-05-20 Phkb  phosphorylase kinase regulatory subunit beta  Phkb  phosphorylase kinase beta subunit  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-04-27 Phkb  phosphorylase kinase beta subunit  Phkb  phosphorylase kinase, beta  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-01-20 Phkb  phosphorylase kinase, beta  Phkb  phosphorylase kinase beta  Data merged from RGD:1583833 737654 APPROVED
2007-09-11 Phkb  phosphorylase kinase beta  LOC361377  similar to phosphorylase kinase (EC 2.7.1.38) beta chain, non-muscle - rabbit  Symbol and Name updated to reflect Human and Mouse nomenclature 1299863 APPROVED
2006-11-19 LOC361377  similar to phosphorylase kinase (EC 2.7.1.38) beta chain, non-muscle - rabbit      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-01-20 Phkb  phosphorylase kinase, beta      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Phkb  phosphorylase kinase, beta      Symbol and Name status set to provisional 70820 PROVISIONAL